Helen Vander Wende, PhD
Postdoctoral Scholar
Cell and Tissue Biology
School of Dentistry

Education & Training

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• PhD Molecular and Cell Biology University of California 08/2022
• BS Molecular, Cellular, and Developmental Biology University of Washington 12/2012

Publications (7)

Top publication keywords:
LongevityOxygenasesCaenorhabditis elegansBasic-Leucine Zipper Transcription FactorsProtein AggregatesNuclear Pore Complex ProteinsUnfolded Protein ResponseSaccharomyces cerevisiae ProteinsSuperoxide Dismutase-1TransaldolaseAlcohol DehydrogenaseChromosomal Proteins, Non-HistoneDrosophila melanogasterDrosophila ProteinsMeiosis

• Meiotic resetting of the cellular Sod1 pool is driven by protein aggregation, degradation, and transient LUTI-mediated repression.
  The Journal of cell biology 2023 Vander Wende HM, Gopi M, Onyundo M, Medrano C, Adanlawo T, Brar GA
• Tunable Transcriptional Interference at the Endogenous Alcohol Dehydrogenase Gene Locus in Drosophila melanogaster.
  G3 (Bethesda, Md.) 2020 Jorgensen V, Chen J, Vander Wende H, Harris DE, McCarthy A, Breznak S, Wong-Deyrup SW, Chen Y, Rangan P, Brar GA, Sawyer EM, Chan LY, Ünal E
• Transaldolase inhibition impairs mitochondrial respiration and induces a starvation-like longevity response in Caenorhabditis elegans.
  PLoS genetics 2017 Bennett CF, Kwon JJ, Chen C, Russell J, Acosta K, Burnaevskiy N, Crane MM, Bitto A, Vander Wende H, Simko M, Pineda V, Rossner R, Wasko BM, Choi H, Chen S, Park S, Jafari G, Sands B, Perez Olsen C, …
• Recurrent Gene Duplication Diversifies Genome Defense Repertoire in Drosophila.
  Molecular biology and evolution 2016 Levine MT, Vander Wende HM, Hsieh E, Baker EP, Malik HS
• A Comprehensive Analysis of Replicative Lifespan in 4,698 Single-Gene Deletion Strains Uncovers Conserved Mechanisms of Aging.
  Cell metabolism 2015 McCormick MA, Delaney JR, Tsuchiya M, Tsuchiyama S, Shemorry A, Sim S, Chou AC, Ahmed U, Carr D, Murakami CJ, Schleit J, Sutphin GL, Wasko BM, Bennett CF, Wang AM, Olsen B, Beyer RP, Bammler TK, …
• Mitotic fidelity requires transgenerational action of a testis-restricted HP1.
  eLife 2015 Levine MT, Vander Wende HM, Malik HS
• Activation of the mitochondrial unfolded protein response does not predict longevity in Caenorhabditis elegans.
  Nature communications 2014 Bennett CF, Vander Wende H, Simko M, Klum S, Barfield S, Choi H, Pineda VV, Kaeberlein M