Guohua Yuan, PhD
Postdoctoral Scholar
Neurological Surgery
School of Medicine

Awards

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• Award for Outstanding Research Achievement, THU-IDG/McGovern Institute of Tsinghua University, 2022
• Comprehensive Prize for Graduate Students, Tsinghua University, 2021
• The Agilent Scholarship, Tsinghua University, 2020
• The Future Scholar Fellowship, Tsinghua University, 2016-2020
• The Excellent Graduates Award, Xiamen University, 2016
• National Scholarship for Graduate Students, Xiamen University, 2015
• First prize of the ninth Challenge Cup National College Students’ Extracurricular Science, Henan Province, 2011

Education & Training

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• Ph.D. Biology Tsinghua University 01/2022
• Master Physics Xiamen University 06/2016
• B. Eng. Materials Science and Engineering Zhengzhou University 06/2013

Publications (6)

Top publication keywords:
ConnectinT-Lymphocytes, RegulatoryModels, ChemicalBacterial ProteinsProtein DomainsElasticityMagneticsCalciumProtein StabilityImmunoglobulin DomainsChromatinThermodynamicsForkhead Transcription FactorsProtein FoldingMicroscopy, Atomic Force

• Sustained store-operated calcium entry utilizing activated chromatin state leads to instability in iTregs.
  eLife 2023 Lyu H, Yuan G, Liu X, Wang X, Geng S, Xia T, Zhou X, Li Y, Hu X, Shi Y
• Hidden Intermediate State and Second Pathway Determining Folding and Unfolding Dynamics of GB1 Protein at Low Forces.
  Physical review letters 2020 Guo Z, Hong H, Yuan G, Qian H, Li B, Cao Y, Wang W, Wu CX, Chen H
• Improved data analysis method of single-molecule experiments based on probability optimization
  Chinese Physics B 2018 Weili Zhai, Guohua Yuan, Chao Liu, Hu Chen.
• Elasticity of the Transition State Leading to an Unexpected Mechanical Stabilization of Titin Immunoglobulin Domains.
  Angewandte Chemie (International ed. in English) 2017 Yuan G, Le S, Yao M, Qian H, Zhou X, Yan J, Chen H
• The kinetics of forcedependent hybridization and strand-peeling of short DNA fragments
  Science China Physics, Mechanics & Astronomy 2016 Zhoujie Yang, Guohua Yuan, Weili Zhai, Jie Yan, Hu Chen.
• Dynamics of equilibrium folding and unfolding transitions of titin immunoglobulin domain under constant force
  J Am Chem Soc 2015 Hu Chen, Guohua Yuan (co-first author), Ricksen S. Winardhi, Mingxi Yao, Ionel Popa, Julio M. Fernandez, and Jie Yan