Guofei Cui, PhD
Postdoctoral Scholar
Dermatology
School of Medicine

Interests

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• liver cancer
• signal pathway
• epigenetics
• transcription regulation
• cancer therapy

Publications (10)

Top publication keywords:
CholangiocarcinomaNeurosporaCatalaseProto-Oncogene Proteins c-aktMechanistic Target of Rapamycin Complex 1Neurospora crassaCarcinogenesisPhosphoproteinsLiver NeoplasmsT-Box Domain ProteinsMechanistic Target of Rapamycin Complex 2Carcinoma, HepatocellularBile Duct NeoplasmsTranscription, GeneticTranscription Factors

• TSC/mTORC1 mediates mTORC2/AKT1 signaling in c-MYC-induced murine hepatocarcinogenesis via centromere protein M.
  The Journal of clinical investigation 2024 Zhou Y, Zhang S, Qiu G, Wang X, Yonemura A, Xu H, Cui G, Deng S, Chun J, Chen N, Xu M, Song X, Wang J, Xu Z, Deng Y, Evert M, Calvisi DF, Lin S, Wang H, Chen X
• Overexpression of TBX3 suppresses tumorigenesis in experimental and human cholangiocarcinoma.
  Cell death & disease 2024 Deng S, Lu X, Wang X, Liang B, Xu H, Yang D, Cui G, Yonemura A, Paine H, Zhou Y, Zhang Y, Simile MM, Urigo F, Evert M, Calvisi DF, Green BL, Chen X
• Sensing of H2O2-induced oxidative stress by the UPF factor complex is crucial for activation of catalase-3 expression in Neurospora.
  PLoS genetics 2023 Shen S, Zhang C, Meng Y, Cui G, Wang Y, Liu X, He Q
• Loss of TP53 cooperates with c-MET overexpression to drive hepatocarcinogenesis.
  Cell death & disease 2023 Zhou Y, Cui G, Xu H, Chun J, Yang D, Zhang Z, Yang L, Wang J, Wan M, Calvisi DF, Lin S, Chen X, Wang H
• Combination of AFP vaccine and immune checkpoint inhibitors slows hepatocellular carcinoma progression in preclinical models.
  The Journal of clinical investigation 2023 Lu X, Deng S, Xu J, Green BL, Zhang H, Cui G, Zhou Y, Zhang Y, Xu H, Zhang F, Mao R, Zhong S, Cramer T, Evert M, Calvisi DF, He Y, Liu C, Chen X

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• β-Catenin Sustains and Is Required for YES-associated Protein Oncogenic Activity in Cholangiocarcinoma.
  Gastroenterology 2022 Zhang Y, Xu H, Cui G, Liang B, Chen X, Ko S, Affo S, Song X, Liao Y, Feng J, Wang P, Wang H, Xu M, Wang J, Pes GM, Ribback S, Zeng Y, Singhi A, Schwabe RF, Monga SP, Evert M, Tang L, Calvisi DF, Chen …
• RASSF1A independence and early galectin-1 upregulation in PIK3CA-induced hepatocarcinogenesis: new therapeutic venues.
  Molecular oncology 2021 Scheiter A, Evert K, Reibenspies L, Cigliano A, Annweiler K, Müller K, Pöhmerer LM, Xu H, Cui G, Itzel T, Materna-Reichelt S, Coluccio A, Honarnejad K, Teufel A, Brochhausen C, Dombrowski F, Chen X, …
• NC2 complex is a key factor for the activation of catalase-3 transcription by regulating H2A.Z deposition.
  Nucleic acids research 2020 Cui G, Dong Q, Duan J, Zhang C, Liu X, He Q
• Author Correction: FRQ-CK1 interaction determines the period of circadian rhythms in Neurospora.
  Nature communications 2020 Liu X, Chen A, Caicedo-Casso A, Cui G, Du M, He Q, Lim S, Kim HJ, Hong CI, Liu Y
• FRQ-CK1 interaction determines the period of circadian rhythms in Neurospora.
  Nature communications 2019 Liu X, Chen A, Caicedo-Casso A, Cui G, Du M, He Q, Lim S, Kim HJ, Hong CI, Liu Y