Georgios Batsios, PhD
Associate Specialist
Radiology
School of Medicine

Awards

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• ISMRM Junior Fellow, International Society for Magnetic Resonance in Medicine (ISMRM), 2022
• Hasegawa award, UCSF Radiology and Biomedical Imaging department, 2022
• Sholarship, Bodossaki Foundation, 2008-2010
• Sholarship, Greek National Scholarship Foundation, 2006

Education & Training

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• Postdoctoral Fellowship Biomedical Imaging University of California, San Francisco 2021
• Ph.D. Biomedical Engineering ETH Zurich 2016
• Master in Biomedical Engineering Biomedical Engineering (Bioimaging) ETH Zurich 2010
• Diploma Electrical and Computer Engineering National Technical University of Athens (NTUA) 2008

Interests

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• Hyperpolarized 13C imaging
• Metabolic diseases
• Kinetic modeling
• Cancer
• MR biomarkers
• Brain tumors
• Magnetic resonance spectroscopy and imaging
• Metabolism
• Deuterium (2H) metabolic imaging
• Molecular imaging

Publications (19)

Top publication keywords:
TelomeraseGliomaGlioblastomaPyruvic AcidDeuteriumMolecular ImagingBrain NeoplasmsPhosphatidylinositol 3-Kinasesgamma-GlutamyltransferaseTOR Serine-Threonine KinasesNeoplasm ProteinsXenograft Model Antitumor AssaysCarbon IsotopesIsocitrate DehydrogenaseGlutarates

• GABA production induced by imipridones is a targetable and imageable metabolic alteration in diffuse midline gliomas.
  bioRxiv : the preprint server for biology 2024 Batsios G, Udutha S, Taglang C, Gillespie AM, Lau B, Ji S, Phoenix T, Mueller S, Venneti S, Koschmann C, Viswanath P
• Telomerase reverse transcriptase induces targetable alterations in glutathione and nucleotide biosynthesis in glioblastomas.
  bioRxiv : the preprint server for biology 2023 Udutha S, Taglang C, Batsios G, Gillespie AM, Tran M, Ronen SM, Ten Hoeve J, Graeber TG, Viswanath P
• Imaging telomerase reverse transcriptase expression in oligodendrogliomas using hyperpolarized δ-[1-13C]-gluconolactone.
  Neuro-oncology advances 2023 Batsios G, Taglang C, Gillespie AM, Viswanath P
• Hyperpolarized δ-[1- 13C]gluconolactone imaging visualizes response to TERT or GABPB1 targeting therapy for glioblastoma.
  Scientific reports 2023 Minami N, Hong D, Taglang C, Batsios G, Gillespie AM, Viswanath P, Stevers N, Barger CJ, Costello JF, Ronen SM
• Imaging biomarkers of TERT or GABPB1 silencing in TERT-positive glioblastoma.
  Neuro-oncology 2022 Minami N, Hong D, Stevers N, Barger CJ, Radoul M, Hong C, Chen L, Kim Y, Batsios G, Gillespie AM, Pieper RO, Costello JF, Viswanath P, Ronen SM

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• A 13C/31P surface coil to visualize metabolism and energetics in the rodent brain at 3 Tesla.
  Journal of magnetic resonance (San Diego, Calif. : 1997) 2022 Vaidya MV, Zhang B, Hong D, Brown R, Batsios G, Viswanath P, Paska J, Wulf G, Grant AK, Ronen SM, Larson PEZ
• Deuterium Metabolic Imaging Reports on TERT Expression and Early Response to Therapy in Cancer.
  Clinical cancer research : an official journal of the American Association for Cancer Research 2022 Batsios G, Taglang C, Tran M, Stevers N, Barger C, Gillespie AM, Ronen SM, Costello JF, Viswanath P
• Deuterium magnetic resonance spectroscopy enables noninvasive metabolic imaging of tumor burden and response to therapy in low-grade gliomas.
  Neuro-oncology 2022 Taglang C, Batsios G, Mukherjee J, Tran M, Gillespie AM, Hong D, Ronen SM, Artee Luchman H, Pieper RO, Viswanath P
• Acquisition and quantification pipeline for in vivo hyperpolarized 13 C MR spectroscopy.
  Magnetic resonance in medicine 2021 Hong D, Batsios G, Viswanath P, Gillespie AM, Vaidya M, Larson PEZ, Ronen SM
• Pan-cancer imaging of TERT expression using deuterium magnetic resonance spectroscopy-based assessment of pyruvate metabolism
  bioRxiv 2021 Batsios G, Taglang C, Tran M, Stevers N, Barger C, Gillespie AM, Ronen S, Costello J, Viswanath P
• Metabolic imaging detects elevated glucose flux through the pentose phosphate pathway associated with TERT expression in low-grade gliomas.
  Neuro-oncology 2021 Viswanath P, Batsios G, Ayyappan V, Taglang C, Gillespie AM, Larson PEZ, Luchman HA, Costello JF, Pieper RO, Ronen SM
• Imaging 6-Phosphogluconolactonase Activity in Brain Tumors In Vivo Using Hyperpolarized δ-[1-13C]gluconolactone.
  Frontiers in oncology 2021 Batsios G, Taglang C, Cao P, Gillespie AM, Najac C, Subramani E, Wilson DM, Flavell RR, Larson PEZ, Ronen SM, Viswanath P
• Non-invasive assessment of telomere maintenance mechanisms in brain tumors.
  Nature communications 2021 Viswanath P, Batsios G, Mukherjee J, Gillespie AM, Larson PEZ, Luchman HA, Phillips JJ, Costello JF, Pieper RO, Ronen SM
• Glutamate Is a Noninvasive Metabolic Biomarker of IDH1-Mutant Glioma Response to Temozolomide Treatment.
  Cancer research 2020 Subramani E, Radoul M, Najac C, Batsios G, Molloy AR, Hong D, Gillespie AM, Santos RD, Viswanath P, Costello JF, Pieper RO, Ronen SM
• MR-detectable metabolic biomarkers of response to mutant IDH inhibition in low-grade glioma.
  Theranostics 2020 Molloy AR, Najac C, Viswanath P, Lakhani A, Subramani E, Batsios G, Radoul M, Gillespie AM, Pieper RO, Ronen SM
• In vivo detection of γ-glutamyl-transferase up-regulation in glioma using hyperpolarized γ-glutamyl-[1-13C]glycine.
  Scientific reports 2020 Batsios G, Najac C, Cao P, Viswanath P, Subramani E, Saito Y, Gillespie AM, Yoshihara HAI, Larson P, Sando S, Ronen SM
• PI3K/mTOR inhibition of IDH1 mutant glioma leads to reduced 2HG production that is associated with increased survival.
  Scientific reports 2019 Batsios G, Viswanath P, Subramani E, Najac C, Gillespie AM, Santos RD, Molloy AR, Pieper RO, Ronen SM
• In vivo investigation of hyperpolarized [1,3-13C2]acetoacetate as a metabolic probe in normal brain and in glioma.
  Scientific reports 2019 Najac C, Radoul M, Le Page LM, Batsios G, Subramani E, Viswanath P, Gillespie AM, Ronen SM
• Hybrid multiband excitation multiecho acquisition for hyperpolarized (13) C spectroscopic imaging.
  Magnetic resonance in medicine 2014 Sigfridsson A, Weiss K, Wissmann L, Busch J, Krajewski M, Batel M, Batsios G, Ernst M, Kozerke S