Geoffrey Manley, MD, PhD
Professor
Neurological Surgery
School of Medicine

This work spans from the laboratory to the bedside in an effort to develop translational models and data repositories to improve the diagnosis, prognosis and treatment of mild to severe brain injuries. He is the Contact Principal Investigator for both the Transforming Research and Clinical Knowledge in Traumatic Brain Injury (TRACK-TBI) U01 research project funded by the National Institute of Neurological Disorders and Strokee and the Department of Defense TBI Endpoints Development (TED) Initiative. Dr. Manley is also the contact PI of the recently awarded TRACK-TBI Network that will soon be launching innovative phase 2 clinical TBI trials.

• Clinical Outcomes After Traumatic Brain Injury and Exposure to Extracranial Surgery: A TRACK-TBI Study.
  JAMA surgery 2024 Roberts CJ, Barber J, Temkin NR, Dong A, Robertson CS, Valadka AB, Yue JK, Markowitz AJ, Manley GT, Nelson LD, Transforming Clinical Research and Knowledge in TBI (TRACK-TBI) Investigators, Badjatia N…
• Medicaid Insurance is a Predictor of Prolonged Hospital Length of Stay After Traumatic Brain Injury: A Stratified National Trauma Data Bank Cohort Analysis of 552 949 Patients.
  Neurosurgery 2024 Yue JK, Ramesh R, Krishnan N, Chyall L, Halabi C, Huang MC, Manley GT, Tarapore PE, DiGiorgio AM
• Network analysis and relationship of symptom factors to functional outcomes and quality of life following mild traumatic brain injury: a TRACK-TBI study.
  Frontiers in neurology 2023 Eagle SR, Jain S, Sun X, Preszler J, McCrea MA, Giacino JT, Manley GT, Okonkwo DO, Nelson LD, TRACK-TBI Investigators
• Data-driven distillation and precision prognosis in traumatic brain injury with interpretable machine learning.
  Scientific reports 2023 Tritt A, Yue JK, Ferguson AR, Torres Espin A, Nelson LD, Yuh EL, Markowitz AJ, Manley GT, Bouchard KE, TRACK-TBI Investigators
• Profiles of Cognitive Functioning at 6 Months After Traumatic Brain Injury Among Patients in Level I Trauma Centers: A TRACK-TBI Study.
  JAMA network open 2023 Bryant AM, Rose NB, Temkin NR, Barber JK, Manley GT, McCrea MA, Nelson LD, TRACK-TBI Investigators, Badjatia N, Gopinath S, Keene CD, Madden C, Ngwenya LB, Puccio A, Robertson C, Schnyer D, Taylor SR,…
• Association Between Insomnia and Mental Health and Neurocognitive Outcomes Following Traumatic Brain Injury.
  Journal of neurotrauma 2023 Wickwire EM, Albrecht JS, Capaldi VF, Jain S, Gardner RC, Smith MT, Williams SG, Collen J, Schnyer DM, Giacino JT, Nelson LD, Mukherjee P, Sun X, Werner JK, Mosti CB, Markowitz AJ, Manley GT, Krystal …
• Predicting Functional Dependency in Patients with Disorders of Consciousness: A TBI-Model Systems and TRACK-TBI Study.
  Annals of neurology 2023 Snider SB, Temkin NR, Barber J, Edlow BL, Giacino JT, Hammond FM, Izzy S, Kowalski RG, Markowitz AJ, Rovito CA, Shih SL, Zafonte RD, Manley GT, Bodien YG, TRACK-TBI investigators
• Safety and comparative efficacy of initiating low-molecular-weight heparin within 24 hours of injury or surgery for venous thromboembolism prophylaxis in patients with spinal cord injury: a prospective TRACK-SCI registry study.
  Neurosurgical focus 2023 Lui A, Park C, Chryssikos T, Radabaugh H, Patel A, Aabedi AA, Ferguson AR, Torres Espin A, Mummaneni PV, Dhall SS, Duong-Fernandez X, Saigal R, Chou A, Pan J, Singh V, Hemmerle DD, Kyritsis N, Talbott…
• Longitudinal Recovery Following Repetitive Traumatic Brain Injury.
  JAMA network open 2023 Etemad LL, Yue JK, Barber J, Nelson LD, Bodien YG, Satris GG, Belton PJ, Madhok DY, Huie JR, Hamidi S, Tracey JX, Coskun BC, Wong JC, Yuh EL, Mukherjee P, Markowitz AJ, Huang MC, Tarapore PE, …
• Integrating, Harmonizing, and Curating Studies With High-Frequency and Hourly Physiological Data: Proof of Concept from Seven Traumatic Brain Injury Data Sets.
  Journal of neurotrauma 2023 Yaseen A, Robertson C, Cruz Navarro J, Chen J, Heckler B, DeSantis SM, Temkin N, Barber J, Foreman B, Diaz-Arrastia R, Chesnut R, Manley GT, Wright DW, Vassar M, Ferguson AR, Markowitz AJ, Yamal JM
• Comparative effectiveness of decompressive craniectomy versus craniotomy for traumatic acute subdural hematoma (CENTER-TBI): an observational cohort study.
  EClinicalMedicine 2023 van Essen TA, van Erp IAM, Lingsma HF, Pisica D, Yue JK, Singh RD, van Dijck JTJM, Volovici V, Younsi A, Kolias A, Peppel LD, Heijenbrok-Kal M, Ribbers GM, Menon DK, Hutchinson PJA, Manley GT, …
• Prevalence of and Risk Factors for Post-traumatic Headache in Civilian Patients After Mild Traumatic Brain Injury: A TRACK-TBI Study.
  Mayo Clinic proceedings 2023 Ashina H, Dodick DW, Barber J, Temkin NR, Chong CD, Adler JS, Stein KS, Schwedt TJ, Manley GT, TRACK-TBI Investigators
• Long-term Multidomain Patterns of Change After Traumatic Brain Injury: A TRACK-TBI LONG Study.
  Neurology 2023 Brett BL, Temkin N, Barber JK, Okonkwo DO, Stein M, Bodien YG, Corrigan J, Diaz-Arrastia R, Giacino JT, McCrea MA, Manley GT, Nelson LD, for TRACK-TBI Investigators
• Effect of propranolol and clonidine after severe traumatic brain injury: a pilot randomized clinical trial.
  Critical care (London, England) 2023 Nordness MF, Maiga AW, Wilson LD, Koyama T, Rivera EL, Rakhit S, de Riesthal M, Motuzas CL, Cook MR, Gupta DK, Jackson JC, Williams Roberson S, Meurer WJ, Lewis RJ, Manley GT, Pandharipande PP, Patel …
• Examining later-in-life health risks associated with sport-related concussion and repetitive head impacts: a systematic review of case-control and cohort studies.
  British journal of sports medicine 2023 Iverson GL, Castellani RJ, Cassidy JD, Schneider GM, Schneider KJ, Echemendia RJ, Bailes JE, Hayden KA, Koerte IK, Manley GT, McNamee M, Patricios JS, Tator CH, Cantu RC, Dvorak J
• Socioeconomic and clinical factors associated with prolonged hospital length of stay after traumatic brain injury.
  Injury 2023 Yue JK, Krishnan N, Chyall L, Vega P, Hamidi S, Etemad LL, Tracey JX, Tarapore PE, Huang MC, Manley GT, DiGiorgio AM
• The American Congress of Rehabilitation Medicine Diagnostic Criteria for Mild Traumatic Brain Injury.
  Archives of physical medicine and rehabilitation 2023 Silverberg ND, Iverson GL, ACRM Brain Injury Special Interest Group Mild TBI Task Force members:, Cogan A, Dams-O-Connor K, Delmonico R, Graf MJP, Iaccarino MA, Kajankova M, Kamins J, McCulloch KL, …
• Associations of Microvascular Injury-Related Biomarkers With Traumatic Brain Injury Severity and Outcomes: A Transforming Research and Clinical Knowledge in Traumatic Brain Injury (TRACK-TBI) Pilot Study.
  Journal of neurotrauma 2023 Schneider ALC, Huie JR, Jain S, Sun X, Ferguson AR, Lynch C, Yue JK, Manley GT, Wang KKW, Sandsmark DK, Campbell C, Diaz-Arrastia R
• Managing outcome expectations after Traumatic Brain Injury.
  Injury 2023 Maas AIR, Hemphill JC, Wilson L, Manley GT
• Prognostication and Goals of Care Decisions in Severe Traumatic Brain Injury: A Survey of The Seattle International Severe Traumatic Brain Injury Consensus Conference Working Group.
  Journal of neurotrauma 2023 Sarigul B, Bell RS, Chesnut R, Aguilera S, Buki A, Citerio G, Cooper DJ, Diaz-Arrastia R, Diringer M, Figaji A, Gao G, Geocadin RG, Ghajar J, Harris O, Hoffer A, Hutchinson P, Joseph M, Kitagawa R, …
• Decompressive Craniectomy versus Craniotomy for Acute Subdural Hematoma.
  The New England journal of medicine 2023 Hutchinson PJ, Adams H, Mohan M, Devi BI, Uff C, Hasan S, Mee H, Wilson MH, Gupta DK, Bulters D, Zolnourian A, McMahon CJ, Stovell MG, Al-Tamimi YZ, Tewari MK, Tripathi M, Thomson S, Viaroli E, Belli …
• Response to Hutchinson M. "The Concept of Mild Traumatic Brain Injury: Response to Palacios et al." (doi: 10.1089/neu.2023.0011).
  Journal of neurotrauma 2023 Mukherjee P, Palacios EM, Manley GT
• Neuroinflammatory Biomarkers for Traumatic Brain Injury Diagnosis and Prognosis: A TRACK-TBI Pilot Study.
  Neurotrauma reports 2023 Yue JK, Kobeissy FH, Jain S, Sun X, Phelps RRL, Korley FK, Gardner RC, Ferguson AR, Huie JR, Schneider ALC, Yang Z, Xu H, Lynch CE, Deng H, Rabinowitz M, Vassar MJ, Taylor SR, Mukherjee P, Yuh EL, …
• A standardized postoperative bowel regimen protocol after spine surgery.
  Frontiers in surgery 2023 Yue JK, Krishnan N, Wang AS, Chung JE, Etemad LL, Manley GT, Tarapore PE
• Hypotension requiring vasopressor treatment and increased cardiac complications in elderly spinal cord injury patients: a prospective TRACK-SCI registry study.
  Journal of neurosurgery. Spine 2023 Agarwal N, Blitstein J, Lui A, Torres-Espin A, Vasnarungruengkul C, Burke J, Mummaneni PV, Dhall SS, Weinstein PR, Duong-Fernandez X, Chou A, Pan J, Singh V, Ferguson AR, Hemmerle DD, Kyritsis N, …
• Predicting Functional Dependency in Patients with Disorders of Consciousness: A TBI-Model Systems and TRACK-TBI Study.
  medRxiv : the preprint server for health sciences 2023 Snider SB, Temkin NR, Barber J, Edlow BL, Giacino JT, Hammond FM, Izzy S, Kowalski RG, Markowitz AJ, Rovito CA, Shih SL, Zafonte RD, Manley GT, Bodien YG, TRACK-TBI Investigators
• Neuroworsening in the Emergency Department Is a Predictor of Traumatic Brain Injury Intervention and Outcome: A TRACK-TBI Pilot Study.
  Journal of clinical medicine 2023 Yue JK, Krishnan N, Kanter JH, Deng H, Okonkwo DO, Puccio AM, Madhok DY, Belton PJ, Lindquist BE, Satris GG, Lee YM, Umbach G, Duhaime AC, Mukherjee P, Yuh EL, Valadka AB, DiGiorgio AM, Tarapore PE, …
• Functional Recovery, Symptoms, and Quality of Life 1 to 5 Years After Traumatic Brain Injury.
  JAMA network open 2023 Nelson LD, Temkin NR, Barber J, Brett BL, Okonkwo DO, McCrea MA, Giacino JT, Bodien YG, Robertson C, Corrigan JD, Diaz-Arrastia R, Markowitz AJ, Manley GT, TRACK-TBI Investigators
• Towards further progress in traumatic brain injury - Authors' reply.
  The Lancet. Neurology 2023 Maas AIR, Menon DK, Manley GT
• Polygenic risk for mental disorders as predictors of posttraumatic stress disorder after mild traumatic brain injury.
  Translational psychiatry 2023 Stein MB, Jain S, Parodi L, Choi KW, Maihofer AX, Nelson LD, Mukherjee P, Sun X, He F, Okonkwo DO, Giacino JT, Korley FK, Vassar MJ, Robertson CS, McCrea MA, Temkin N, Markowitz AJ, Diaz-Arrastia R, …
• On-Call Junior Neurosurgery Residents Spend 9 hours of Their On-Call Shift Actively Using the Electronic Health Record.
  Neurosurgery 2022 Patel A, Mummaneni PV, Zheng J, Rosner BI, Thombley R, Sorour O, Theodosopoulos PV, Aghi MK, Berger MS, Chang EF, Chou D, Manley GT, DiGiorgio AM
• Correction to: Association of day-of-injury plasma glial fibrillary acidic protein concentration and six-month posttraumatic stress disorder in patients with mild traumatic brain injury.
  Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2022 Kulbe JR, Jain S, Nelson LD, Korley FK, Mukherjee P, Sun X, Okonkwo DO, Giacino JT, Vassar MJ, Robertson CS, McCrea MA, Wang KKW, Temkin N, Mac Donald CL, Taylor SR, Ferguson AR, Markowitz AJ, Diaz-…
• Effects of age and time since injury on traumatic brain injury blood biomarkers: a TRACK-TBI study.
  Brain communications 2022 Gardner RC, Puccio AM, Korley FK, Wang KKW, Diaz-Arrastia R, Okonkwo DO, Puffer RC, Yuh EL, Yue JK, Sun X, Taylor SR, Mukherjee P, Jain S, Manley GT, TRACK-TBI Investigators
• Feasibility and Utility of a Flexible Outcome Assessment Battery for Longitudinal Traumatic Brain Injury Research: A TRACK-TBI Study.
  Journal of neurotrauma 2022 Bodien YG, Barber J, Taylor SR, Boase K, Corrigan JD, Dikmen S, Gardner RC, Kramer JH, Levin H, Machamer J, McAllister T, Nelson LD, Ngwenya LB, Sherer M, Stein MB, Vassar M, Whyte J, Yue JK, …
• Traumatic brain injury: progress and challenges in prevention, clinical care, and research.
  The Lancet. Neurology 2022 Maas AIR, Menon DK, Manley GT, Abrams M, Åkerlund C, Andelic N, Aries M, Bashford T, Bell MJ, Bodien YG, Brett BL, Büki A, Chesnut RM, Citerio G, Clark D, Clasby B, Cooper DJ, Czeiter E, Czosnyka M, …
• Emotional Resilience Predicts Preserved White Matter Microstructure Following Mild Traumatic Brain Injury.
  Biological psychiatry. Cognitive neuroscience and neuroimaging 2022 Cai LT, Brett BL, Palacios EM, Yuh EL, Bourla I, Wren-Jarvis J, Wang Y, Mac Donald C, Diaz-Arrastia R, Giacino JT, Okonkwo DO, Levin HS, Robertson CS, Temkin N, Markowitz AJ, Manley GT, Stein MB, …
• Predictors of Extreme Hospital Length of Stay After Traumatic Brain Injury.
  World neurosurgery 2022 Yue JK, Krishnan N, Chyall L, Haddad AF, Vega P, Caldwell DJ, Umbach G, Tantry E, Tarapore PE, Huang MC, Manley GT, DiGiorgio AM
• Prognostic value of day-of-injury plasma GFAP and UCH-L1 concentrations for predicting functional recovery after traumatic brain injury in patients from the US TRACK-TBI cohort: an observational cohort study.
  The Lancet. Neurology 2022 Korley FK, Jain S, Sun X, Puccio AM, Yue JK, Gardner RC, Wang KKW, Okonkwo DO, Yuh EL, Mukherjee P, Nelson LD, Taylor SR, Markowitz AJ, Diaz-Arrastia R, Manley GT, TRACK-TBI Study Investigators
• Traumatic brain injury over the past 20 years: research and clinical progress.
  The Lancet. Neurology 2022 Maas AIR, Fitzgerald M, Gao G, Gupta D, Hutchinson P, Manley GT, Menon DK
• Developing a National Trauma Research Action Plan: Results from the long-term outcomes research gap Delphi survey.
  The journal of trauma and acute care surgery 2022 Herrera-Escobar JP, Reidy E, Phuong J, Brasel KJ, Cuschieri J, Fallat M, Potter BK, Price MA, Bulger EM, Haider AH, Bonne S, Brasel KJ, Cuschieri J, de Roon-Cassini T, Dicker RA, Fallat M, Ficke JR, …
• Outcomes in Patients With Mild Traumatic Brain Injury Without Acute Intracranial Traumatic Injury.
  JAMA network open 2022 Madhok DY, Rodriguez RM, Barber J, Temkin NR, Markowitz AJ, Kreitzer N, Manley GT, TRACK-TBI Investigators
• Risk Factors for High Symptom Burden Three Months after Traumatic Brain Injury and Implications for Clinical Trial Design: A Transforming Research and Clinical Knowledge in Traumatic Brain Injury Study.
  Journal of neurotrauma 2022 Temkin N, Machamer J, Dikmen S, Nelson LD, Barber J, Hwang PH, Boase K, Stein MB, Sun X, Giacino J, McCrea MA, Taylor SR, Jain S, Manley G, TRACK-TBI Investigators
• Diffusion Tensor Imaging Reveals Elevated Diffusivity of White Matter Microstructure that Is Independently Associated with Long-Term Outcome after Mild Traumatic Brain Injury: A TRACK-TBI Study.
  Journal of neurotrauma 2022 Palacios EM, Yuh EL, Mac Donald CL, Bourla I, Wren-Jarvis J, Sun X, Vassar MJ, Diaz-Arrastia R, Giacino JT, Okonkwo DO, Robertson CS, Stein MB, Temkin N, McCrea MA, Levin HS, Markowitz AJ, Jain S, …
• Evacuation of a multi-loculated acute-on-chronic subdural hematoma using tandem bedside subdural evacuation port systems.
  Trauma case reports 2022 Yue JK, Haddad AF, Wang AS, Caldwell DJ, Umbach G, Digiorgio AM, Tarapore PE, Huang MC, Manley GT
• Association of day-of-injury plasma glial fibrillary acidic protein concentration and six-month posttraumatic stress disorder in patients with mild traumatic brain injury.
  Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2022 Kulbe JR, Jain S, Nelson LD, Korley FK, Mukherjee P, Sun X, Okonkwo DO, Giacino JT, Vassar MJ, Robertson CS, McCrea MA, Wang KKW, Temkin N, Mac Donald CL, Taylor SR, Ferguson AR, Markowitz AJ, Diaz-…
• Employment and Economic Outcomes of Participants With Mild Traumatic Brain Injury in the TRACK-TBI Study.
  JAMA network open 2022 Gaudette É, Seabury SA, Temkin N, Barber J, DiGiorgio AM, Markowitz AJ, Manley GT, TRACK-TBI Investigators
• Improving the Precision of the Glasgow Outcome Scale-Extended Using Item Response Theory: A TRACK-TBI Study.
  Journal of neurotrauma 2022 Magnus BE, Balsis S, Giacino JT, McCrea MA, Temkin NR, Whyte J, Manley GT, Nelson LD, TRACK-TBI Investigators
• Is the Centers for Medicare and Medicaid Services Hierarchical Condition Category Risk Adjustment Model Satisfactory for Quantifying Risk After Spine Surgery?
  Neurosurgery 2022 Chan AK, Shahrestani S, Ballatori AM, Orrico KO, Manley GT, Tarapore PE, Huang M, Dhall SS, Chou D, Mummaneni PV, DiGiorgio AM
• The Case for Optimized Edge-Centric Tractography at Scale.
  Frontiers in neuroinformatics 2022 Moon JY, Mukherjee P, Madduri RK, Markowitz AJ, Cai LT, Palacios EM, Manley GT, Bremer PT
• Expert-augmented automated machine learning optimizes hemodynamic predictors of spinal cord injury outcome.
  PloS one 2022 Chou A, Torres-Espin A, Kyritsis N, Huie JR, Khatry S, Funk J, Hay J, Lofgreen A, Shah R, McCann C, Pascual LU, Amorim E, Weinstein PR, Manley GT, Dhall SS, Pan JZ, Bresnahan JC, Beattie MS, Whetstone…
• Empowering Data Sharing and Analytics through the Open Data Commons for Traumatic Brain Injury Research.
  Neurotrauma reports 2022 Chou A, Torres-Espín A, Huie JR, Krukowski K, Lee S, Nolan A, Guglielmetti C, Hawkins BE, Chaumeil MM, Manley GT, Beattie MS, Bresnahan JC, Martone ME, Grethe JS, Rosi S, Ferguson AR
• Decision tree-based machine learning analysis of intraoperative vasopressor use to optimize neurological improvement in acute spinal cord injury.
  Neurosurgical focus 2022 Agarwal N, Aabedi AA, Torres-Espin A, Chou A, Wozny TA, Mummaneni PV, Burke JF, Ferguson AR, Kyritsis N, Dhall SS, Weinstein PR, Duong-Fernandez X, Pan J, Singh V, Hemmerle DD, Talbott JF, Whetstone …
• Incidence and Clinical Impact of Myocardial Injury Following Traumatic Brain Injury: A Pilot TRACK-TBI Study.
  Journal of neurosurgical anesthesiology 2022 Krishnamoorthy V, Manley GT, Jain S, Sun S, Foreman B, Komisarow J, Laskowitz DT, Mathew JP, Hernandez A, James ML, Vavilala MS, Markowitz AJ, Korley FK, TRACK-TBI Investigators
• A genome-wide association study of outcome from traumatic brain injury.
  EBioMedicine 2022 Kals M, Kunzmann K, Parodi L, Radmanesh F, Wilson L, Izzy S, Anderson CD, Puccio AM, Okonkwo DO, Temkin N, Steyerberg EW, Stein MB, Manley GT, Maas AIR, Richardson S, Diaz-Arrastia R, Palotie A, …
• Mixture Model Framework for Traumatic Brain Injury Prognosis Using Heterogeneous Clinical and Outcome Data.
  IEEE journal of biomedical and health informatics 2022 Kaplan AD, Cheng Q, Mohan KA, Nelson LD, Jain S, Levin H, Torres-Espin A, Chou A, Huie JR, Ferguson AR, McCrea M, Giacino J, Sundaram S, Markowitz AJ, Manley GT
• How Do Scores on the Functional Status Examination (FSE) Correspond to Scores on the Glasgow Outcome Scale-Extended (GOSE)?
  Neurotrauma reports 2022 Nelson LD, Magnus BE, Temkin NR, Dikmen S, Manley GT, Balsis S
• ADAPTing to a New Era of Comparative Effectiveness Research in Traumatic Brain Injury-Generating Evidence From Observational Data.
  JAMA network open 2022 Manley GT, Lingsma HF, Maas AIR
• Cognitive Outcome 1 Year After Mild Traumatic Brain Injury: Results From the TRACK-TBI Study.
  Neurology 2022 Schneider ALC, Huie JR, Boscardin WJ, Nelson L, Barber JK, Yaffe K, Diaz-Arrastia R, Ferguson AR, Kramer J, Jain S, Temkin N, Yuh E, Manley GT, Gardner RC, TRACK-TBI Investigators
• Blood GFAP as an emerging biomarker in brain and spinal cord disorders.
  Nature reviews. Neurology 2022 Abdelhak A, Foschi M, Abu-Rumeileh S, Yue JK, D'Anna L, Huss A, Oeckl P, Ludolph AC, Kuhle J, Petzold A, Manley GT, Green AJ, Otto M, Tumani H
• Effect of frailty on 6-month outcome after traumatic brain injury: a multicentre cohort study with external validation.
  The Lancet. Neurology 2022 Galimberti S, Graziano F, Maas AIR, Isernia G, Lecky F, Jain S, Sun X, Gardner RC, Taylor SR, Markowitz AJ, Manley GT, Valsecchi MG, Bellelli G, Citerio G, CENTER-TBI and TRACK-TBI participants and …
• Do social determinants of health impact access to neurosurgical care in the United States? A workforce perspective.
  Journal of neurosurgery 2022 Perera S, Hervey-Jumper SL, Mummaneni PV, Barthélemy EJ, Haddad AF, Marotta DA, Burke JF, Chan AK, Manley GT, Tarapore PE, Huang MC, Dhall SS, Chou D, Orrico KO, DiGiorgio AM
• Developing a National Trauma Research Action Plan: Results from the Neurotrauma Research Panel Delphi Survey.
  The journal of trauma and acute care surgery 2022 Stein DM, Braverman MA, Phuong J, Shipper E, Price MA, Bixby PJ, Adelson PD, Ansel BM, Cifu DX, DeVine JG, Galvagno SM, Gelb DE, Harris O, Kang CS, Kitagawa RS, McQuillan KA, Patel MB, Robertson CS, …
• Trajectories of Insomnia in Adults After Traumatic Brain Injury.
  JAMA network open 2022 Wickwire EM, Albrecht JS, Capaldi VF, Jain SO, Gardner RC, Werner JK, Mukherjee P, McKeon AB, Smith MT, Giacino JT, Nelson LD, Williams SG, Collen J, Sun X, Schnyer DM, Markowitz AJ, Manley GT, …
• Association of Posttraumatic Epilepsy With 1-Year Outcomes After Traumatic Brain Injury.
  JAMA network open 2021 Burke J, Gugger J, Ding K, Kim JA, Foreman B, Yue JK, Puccio AM, Yuh EL, Sun X, Rabinowitz M, Vassar MJ, Taylor SR, Winkler EA, Deng H, McCrea M, Stein MB, Robertson CS, Levin HS, Dikmen S, Temkin NR,…
• Correction to: Prognostic Value of Hemorrhagic Brainstem Injury on Early Computed Tomography: A TRACK-TBI Study.
  Neurocritical care 2021 Williams JR, Nieblas-Bedolla E, Feroze A, Young C, Temkin NR, Giacino JT, Okonkwo DO, Manley GT, Barber J, Durfy S, Markowitz AJ, Yuh EL, Mukherjee P, Mac Donald CL, Transforming Research and Clinical…
• Diagnosing Level of Consciousness: The Limits of the Glasgow Coma Scale Total Score.
  Journal of neurotrauma 2021 Bodien YG, Barra A, Temkin NR, Barber J, Foreman B, Vassar M, Robertson C, Taylor SR, Markowitz AJ, Manley GT, Giacino JT, Edlow BL, TRACK-TBI Investigators
• The Morbidity and Mortality of Surgery for Traumatic Brain Injury in Geriatric Patients: A Study of Over 100 000 Patient Cases.
  Neurosurgery 2021 Haddad AF, DiGiorgio AM, Lee YM, Lee AT, Burke JF, Huang MC, Dhall SS, Manley GT, Tarapore PE
• Topological network analysis of patient similarity for precision management of acute blood pressure in spinal cord injury.
  eLife 2021 Torres-Espín A, Haefeli J, Ehsanian R, Torres D, Almeida CA, Huie JR, Chou A, Morozov D, Sanderson N, Dirlikov B, Suen CG, Nielson JL, Kyritsis N, Hemmerle DD, Talbott JF, Manley GT, Dhall SS, …
• FAIR Data Reuse in Traumatic Brain Injury: Exploring Inflammation and Age as Moderators of Recovery in the TRACK-TBI Pilot.
  Frontiers in neurology 2021 Huie JR, Chou A, Torres-Espin A, Nielson JL, Yuh EL, Gardner RC, Diaz-Arrastia R, Manley GT, Ferguson AR, TRACK-TBI Investigators
• Association Between TBI-Related Hearing Impairment and Cognition: A TRACK-TBI Study.
  The Journal of head trauma rehabilitation 2021 Hwang PH, Nelson LD, Sharon JD, McCrea MA, Dikmen SS, Markowitz AJ, Manley GT, Temkin NR, TRACK-TBI Investigators
• Characterization and standardization of multiassay platforms for four commonly studied traumatic brain injury protein biomarkers: a TBI Endpoints Development Study.
  Biomarkers in medicine 2021 Sarkis GA, Zhu T, Yang Z, Li X, Shi Y, Rubenstein R, Yost RA, Manley GT, Wang KK
• Comparing the Quality of Life after Brain Injury-Overall Scale and Satisfaction with Life Scale as Outcome Measures for Traumatic Brain Injury Research.
  Journal of neurotrauma 2021 Kreitzer N, Jain S, Young JS, Sun X, Stein MB, McCrea MA, Levin HS, Giacino JT, Markowitz AJ, Manley GT, Nelson LD, Transforming Research and Clinical Knowledge in Traumatic Brain Injury (TRACK-TBI) …
• Interrater Reliability of National Institutes of Health Traumatic Brain Injury Imaging Common Data Elements for Brain Magnetic Resonance Imaging in Mild Traumatic Brain Injury.
  Journal of neurotrauma 2021 Rincon SP, Mukherjee P, Levin HS, Temkin NR, Mac Donald CL, Krainak DM, Sun X, Jain S, Taylor SR, Markowitz AJ, Kumar A, Manley GT, Yuh EL, TRACK-TBI Investigators
• Depression in Older Adults 12 Months After Traumatic Brain Injury: A TRACK-TBI Study.
  Archives of physical medicine and rehabilitation 2021 Passler JS, Sander AM, Temkin NR, Barber J, Gardner RC, Manley GT, TRACK-TBI Investigators
• Pathological Computed Tomography Features Associated With Adverse Outcomes After Mild Traumatic Brain Injury: A TRACK-TBI Study With External Validation in CENTER-TBI.
  JAMA neurology 2021 Yuh EL, Jain S, Sun X, Pisica D, Harris MH, Taylor SR, Markowitz AJ, Mukherjee P, Verheyden J, Giacino JT, Levin HS, McCrea M, Stein MB, Temkin NR, Diaz-Arrastia R, Robertson CS, Lingsma HF, Okonkwo …
• Functional Outcomes Over the First Year After Moderate to Severe Traumatic Brain Injury in the Prospective, Longitudinal TRACK-TBI Study.
  JAMA neurology 2021 McCrea MA, Giacino JT, Barber J, Temkin NR, Nelson LD, Levin HS, Dikmen S, Stein M, Bodien YG, Boase K, Taylor SR, Vassar M, Mukherjee P, Robertson C, Diaz-Arrastia R, Okonkwo DO, Markowitz AJ, Manley…
• Prognostic Value of Hemorrhagic Brainstem Injury on Early Computed Tomography: A TRACK-TBI Study.
  Neurocritical care 2021 Williams JR, Nieblas-Bedolla E, Feroze A, Young C, Temkin NR, Giacino JT, Okonkwo DO, Manley GT, Barber J, Durfy S, Markowitz AJ, Yuh EL, Mukherjee P, Mac Donald CL, and The Transforming Research and …
• Relationship between transdiagnostic dimensions of psychopathology and traumatic brain injury (TBI): A TRACK-TBI study.
  Journal of abnormal psychology 2021 Nelson LD, Kramer MD, Joyner KJ, Patrick CJ, Stein MB, Temkin N, Levin HS, Whyte J, Markowitz AJ, Giacino J, Manley GT, TRACK-TBI Investigators
• Central Curation of Glasgow Outcome Scale-Extended Data: Lessons Learned from TRACK-TBI.
  Journal of neurotrauma 2021 Boase K, Machamer J, Temkin NR, Dikmen S, Wilson L, Nelson LD, Barber J, Bodien YG, Giacino JT, Markowitz AJ, McCrea MA, Satris G, Stein MB, Taylor SR, Manley GT, TRACK-TBI Investigators
• Aquaporin-4 Reduces Post-Traumatic Seizure Susceptibility by Promoting Astrocytic Glial Scar Formation in Mice.
  Journal of neurotrauma 2021 Lu DC, Zador Z, Yao J, Fazlollahi F, Manley GT
• Comparison of GFAP and UCH-L1 Measurements from Two Prototype Assays: The Abbott i-STAT and ARCHITECT Assays.
  Neurotrauma reports 2021 Korley FK, Datwyler SA, Jain S, Sun X, Beligere G, Chandran R, Marino JA, McQuiston B, Zhang H, Caudle KL, Wang KKW, Puccio AM, Okonkwo DO, Yue JK, Taylor SR, Markowitz A, Manley GT, Diaz-Arrastia R
• A Manual for the Glasgow Outcome Scale-Extended Interview.
  Journal of neurotrauma 2021 Wilson L, Boase K, Nelson LD, Temkin NR, Giacino JT, Markowitz AJ, Maas A, Menon DK, Teasdale G, Manley GT
• Predictors of six-month inability to return to work in previously employed subjects after mild traumatic brain injury: A TRACK-TBI pilot study.
  Journal of concussion 2021 Yue JK, Phelps RR, Hemmerle DD, Upadhyayula PS, Winkler EA, Deng H, Chang D, Vassar MJ, Taylor SR, Schnyer DM, Lingsma HF, Puccio AM, Yuh EL, Mukherjee P, Huang MC, Ngwenya LB, Valadka AB, Markowitz …
• Association of Sex and Age With Mild Traumatic Brain Injury-Related Symptoms: A TRACK-TBI Study.
  JAMA network open 2021 Levin HS, Temkin NR, Barber J, Nelson LD, Robertson C, Brennan J, Stein MB, Yue JK, Giacino JT, McCrea MA, Diaz-Arrastia R, Mukherjee P, Okonkwo DO, Boase K, Markowitz AJ, Bodien Y, Taylor S, Vassar …
• Letter to the Editor. Discrepancies in national databases for TBI estimates.
  Journal of neurosurgery 2021 Madhok DY, Hsia RY, Manley GT
• Diagnostic blood RNA profiles for human acute spinal cord injury.
  The Journal of experimental medicine 2021 Kyritsis N, Torres-Espín A, Schupp PG, Huie JR, Chou A, Duong-Fernandez X, Thomas LH, Tsolinas RE, Hemmerle DD, Pascual LU, Singh V, Pan JZ, Talbott JF, Whetstone WD, Burke JF, DiGiorgio AM, Weinstein…
• Latent Profile Analysis of Neuropsychiatric Symptoms and Cognitive Function of Adults 2 Weeks After Traumatic Brain Injury: Findings From the TRACK-TBI Study.
  JAMA network open 2021 Brett BL, Kramer MD, Whyte J, McCrea MA, Stein MB, Giacino JT, Sherer M, Markowitz AJ, Manley GT, Nelson LD, TRACK-TBI Investigators, Adeoye O, Badjatia N, Boase K, Barber J, Bodien Y, Bullock MR, …
• Tractography-Pathology Correlations in Traumatic Brain Injury: A TRACK-TBI Study.
  Journal of neurotrauma 2021 Nolan AL, Petersen C, Iacono D, Mac Donald CL, Mukherjee P, van der Kouwe A, Jain S, Stevens A, Diamond BR, Wang R, Markowitz AJ, Fischl B, Perl DP, Manley GT, Keene CD, Diaz-Arrastia R, Edlow BL, …
• Risk Factors for Suicidal Ideation Following Mild Traumatic Brain Injury: A TRACK-TBI Study.
  The Journal of head trauma rehabilitation 2021 Campbell-Sills L, Jain S, Sun X, Fisher LB, Agtarap SD, Dikmen S, Nelson LD, Temkin N, McCrea M, Yuh E, Giacino JT, Manley GT, TRACK-TBI Investigators
• High-Sensitivity C-Reactive Protein is a Prognostic Biomarker of Six-Month Disability after Traumatic Brain Injury: Results from the TRACK-TBI Study.
  Journal of neurotrauma 2020 Xu LB, Yue JK, Korley F, Puccio AM, Yuh EL, Sun X, Rabinowitz M, Vassar MJ, Taylor SR, Winkler EA, Puffer RC, Deng H, McCrea M, Stein MB, Robertson CS, Levin HS, Dikmen S, Temkin NR, Giacino JT, …
• An evidence-based methodology for systematic evaluation of clinical outcome assessment measures for traumatic brain injury.
  PloS one 2020 Christoforou AN, Armstrong MJ, Bergin MJG, Robbins A, Merillat SA, Erwin P, Getchius TSD, McCrea M, Markowitz AJ, Manley GT, Giacino JT
• Satisfaction with Life after Mild Traumatic Brain Injury: A TRACK-TBI Study.
  Journal of neurotrauma 2020 Agtarap SD, Campbell-Sills L, Jain S, Sun X, Dikmen S, Levin H, McCrea MA, Mukherjee P, Nelson LD, Temkin N, Yuh EL, Giacino JT, Manley GT, Stein MB, TRACK-TBI Investigators
• Validity of the Brief Test of Adult Cognition by Telephone in Level 1 Trauma Center Patients Six Months Post-Traumatic Brain Injury: A TRACK-TBI Study.
  Journal of neurotrauma 2020 Nelson LD, Barber JK, Temkin NR, Dams-O'Connor K, Dikmen S, Giacino JT, Kramer MD, Levin HS, McCrea MA, Whyte J, Bodien YG, Yue JK, Manley GT, British Neurosurgical Trainee Research Collaborative (…
• Injury volume extracted from MRI predicts neurologic outcome in acute spinal cord injury: A prospective TRACK-SCI pilot study.
  Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 2020 Mummaneni N, Burke JF, DiGiorgio AM, Thomas LH, Duong-Fernandez X, Harris M, Pascual LU, Ferguson AR, Russell Huie J, Pan JZ, Hemmerle DD, Singh V, Torres-Espin A, Omondi C, Kyritsis N, Weinstein PR, …
• Does state malpractice environment affect outcomes following spinal fusions? A robust statistical and machine learning analysis of 549,775 discharges following spinal fusion surgery in the United States.
  Neurosurgical focus 2020 Chan AK, Santacatterina M, Pennicooke B, Shahrestani S, Ballatori AM, Orrico KO, Burke JF, Manley GT, Tarapore PE, Huang MC, Dhall SS, Chou D, Mummaneni PV, DiGiorgio AM
• Smaller Regional Brain Volumes Predict Posttraumatic Stress Disorder at 3 Months After Mild Traumatic Brain Injury.
  Biological psychiatry. Cognitive neuroscience and neuroimaging 2020 Stein MB, Yuh E, Jain S, Okonkwo DO, Mac Donald CL, Levin H, Giacino JT, Dikmen S, Vassar MJ, Diaz-Arrastia R, Robertson CS, Nelson LD, McCrea M, Sun X, Temkin N, Taylor SR, Markowitz AJ, Manley GT, …
• Point-of-Care Platform Blood Biomarker Testing of Glial Fibrillary Acidic Protein versus S100 Calcium-Binding Protein B for Prediction of Traumatic Brain Injuries: A Transforming Research and Clinical Knowledge in Traumatic Brain Injury Study.
  Journal of neurotrauma 2020 Okonkwo DO, Puffer RC, Puccio AM, Yuh EL, Yue JK, Diaz-Arrastia R, Korley FK, Wang KKW, Sun X, Taylor SR, Mukherjee P, Markowitz AJ, Jain S, Manley GT, Transforming Research and Clinical Knowledge in …
• Analysis of Normal High-Frequency Intracranial Pressure Values and Treatment Threshold in Neurocritical Care Patients: Insights into Normal Values and a Potential Treatment Threshold.
  JAMA neurology 2020 Hawryluk GWJ, Nielson JL, Huie JR, Zimmermann L, Saigal R, Ding Q, Hirschi R, Zeiler FA, Ferguson AR, Manley GT
• Sideline Concussion Assessment: The Current State of the Art.
  Neurosurgery 2020 Yue JK, Phelps RRL, Chandra A, Winkler EA, Manley GT, Berger MS
• The evolution of white matter microstructural changes after mild traumatic brain injury: A longitudinal DTI and NODDI study.
  Science advances 2020 Palacios EM, Owen JP, Yuh EL, Wang MB, Vassar MJ, Ferguson AR, Diaz-Arrastia R, Giacino JT, Okonkwo DO, Robertson CS, Stein MB, Temkin N, Jain S, McCrea M, MacDonald CL, Levin HS, Manley GT, Mukherjee…
• Polytrauma Is Associated with Increased Three- and Six-Month Disability after Traumatic Brain Injury: A TRACK-TBI Pilot Study.
  Neurotrauma reports 2020 Yue JK, Satris GG, Dalle Ore CL, Huie JR, Deng H, Winkler EA, Lee YM, Vassar MJ, Taylor SR, Schnyer DM, Lingsma HF, Puccio AM, Yuh EL, Mukherjee P, Valadka AB, Ferguson AR, Markowitz AJ, Okonkwo DO, …
• Clinical Predictors of 3- and 6-Month Outcome for Mild Traumatic Brain Injury Patients with a Negative Head CT Scan in the Emergency Department: A TRACK-TBI Pilot Study.
  Brain sciences 2020 Madhok DY, Yue JK, Sun X, Suen CG, Coss NA, Jain S, Manley GT
• Transforming Research and Clinical Knowledge in Spinal Cord Injury (TRACK-SCI): an overview of initial enrollment and demographics.
  Neurosurgical focus 2020 Tsolinas RE, Burke JF, DiGiorgio AM, Thomas LH, Duong-Fernandez X, Harris MH, Yue JK, Winkler EA, Suen CG, Pascual LU, Ferguson AR, Huie JR, Pan JZ, Hemmerle DD, Singh V, Torres-Espin A, Omondi C, …
• Invariance of the Bifactor Structure of Mild Traumatic Brain Injury (mTBI) Symptoms on the Rivermead Postconcussion Symptoms Questionnaire Across Time, Demographic Characteristics, and Clinical Groups: A TRACK-TBI Study.
  Assessment 2020 Agtarap S, Kramer MD, Campbell-Sills L, Yuh E, Mukherjee P, Manley GT, McCrea MA, Dikmen S, Giacino JT, Stein MB, Nelson LD, TRACK-TBI Investigators <xref ref-type="aff" rid="aff7-1073191120913941"…
• Substance use on admission toxicology screen is associated with peri-injury factors and six-month outcome after traumatic brain injury: A TRACK-TBI Pilot study.
  Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 2020 Yue JK, Phelps RRL, Winkler EA, Deng H, Upadhyayula PS, Vassar MJ, Madhok DY, Schnyer DM, Puccio AM, Lingsma HF, Yuh EL, Mukherjee P, Valadka AB, Okonkwo DO, Manley GT, TRACK-TBI Investigators
• Common Data Elements: Critical Assessment of Harmonization between Current Multi-Center Traumatic Brain Injury Studies.
  Journal of neurotrauma 2020 Meeuws S, Yue JK, Huijben JA, Nair N, Lingsma HF, Bell MJ, Manley GT, Maas AIR
• Revisits, readmissions, and outcomes for pediatric traumatic brain injury in California, 2005-2014.
  PloS one 2020 Hsia RY, Mannix RC, Guo J, Kornblith AE, Lin F, Sokolove PE, Manley GT
• Modeling the characteristics of spontaneous otoacoustic emissions in lizards.
  Hearing research 2019 Wit HP, Manley GA, van Dijk P
• Functional Status Examination Yields Higher Measurement Precision of Functional Limitations after Traumatic Injury than the Glasgow Outcome Scale-Extended: A Preliminary Study.
  Journal of neurotrauma 2019 Nelson LD, Brett BL, Magnus BE, Balsis S, McCrea MA, Manley GT, Temkin N, Dikmen S
• Suppression tuning of spontaneous otoacoustic emissions in the barn owl (Tyto alba).
  Hearing research 2019 Engler S, Köppl C, Manley GA, de Kleine E, van Dijk P
• The Functional Status Examination in Mild Traumatic Brain Injury: A TRACK-TBI Sub-Study.
  Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists 2019 Zahniser E, Temkin NR, Machamer J, Barber J, Manley GT, Markowitz AJ, Dikmen SS, TRACK-TBI Investigators
• Clinical Implementation of Novel Spinal Cord Perfusion Pressure Protocol in Acute Traumatic Spinal Cord Injury at U.S. Level I Trauma Center: TRACK-SCI Study.
  World neurosurgery 2019 Yue JK, Hemmerle DD, Winkler EA, Thomas LH, Fernandez XD, Kyritsis N, Pan JZ, Pascual LU, Singh V, Weinstein PR, Talbott JF, Huie JR, Ferguson AR, Whetstone WD, Manley GT, Beattie MS, Bresnahan JC, …
• Pediatric firearm-related traumatic brain injury in United States trauma centers.
  Journal of neurosurgery. Pediatrics 2019 Deng H, Yue JK, Winkler EA, Dhall SS, Manley GT, Tarapore PE
• Recovery After Mild Traumatic Brain Injury in Patients Presenting to US Level I Trauma Centers: A Transforming Research and Clinical Knowledge in Traumatic Brain Injury (TRACK-TBI) Study.
  JAMA neurology 2019 Nelson LD, Temkin NR, Dikmen S, Barber J, Giacino JT, Yuh E, Levin HS, McCrea MA, Stein MB, Mukherjee P, Okonkwo DO, Robertson CS, Diaz-Arrastia R, Manley GT, and the TRACK-TBI Investigators, Adeoye O…
• The LONI QC System: A Semi-Automated, Web-Based and Freely-Available Environment for the Comprehensive Quality Control of Neuroimaging Data.
  Frontiers in neuroinformatics 2019 Kim H, Irimia A, Hobel SM, Pogosyan M, Tang H, Petrosyan P, Blanco REC, Duffy BA, Zhao L, Crawford KL, Liew SL, Clark K, Law M, Mukherjee P, Manley GT, Van Horn JD, Toga AW
• Association between plasma GFAP concentrations and MRI abnormalities in patients with CT-negative traumatic brain injury in the TRACK-TBI cohort: a prospective multicentre study.
  The Lancet. Neurology 2019 Yue JK, Yuh EL, Korley FK, Winkler EA, Sun X, Puffer RC, Deng H, Choy W, Chandra A, Taylor SR, Ferguson AR, Huie JR, Rabinowitz M, Puccio AM, Mukherjee P, Vassar MJ, Wang KKW, Diaz-Arrastia R, Okonkwo…
• In Reply: Ultra-Early (<12 Hours) Surgery Correlates With Higher Rate of American Spinal Injury Association Impairment Scale Conversion After Cervical Spinal Cord Injury.
  Neurosurgery 2019 Burke JF, Yue JK, Ngwenya LB, Winkler EA, Talbott JF, Pan JZ, Ferguson AR, Beattie MS, Bresnahan JC, Haefeli J, Whetstone WD, Suen CG, Huang MC, Manley GT, Tarapore PE, Dhall SS
• Ultra-Early (<12 Hours) Surgery Correlates With Higher Rate of American Spinal Injury Association Impairment Scale Conversion After Cervical Spinal Cord Injury.
  Neurosurgery 2019 Burke JF, Yue JK, Ngwenya LB, Winkler EA, Talbott JF, Pan JZ, Ferguson AR, Beattie MS, Bresnahan JC, Haefeli J, Whetstone WD, Suen CG, Huang MC, Manley GT, Tarapore PE, Dhall SS
• Sleep disturbances precede depressive symptomatology following traumatic brain injury.
  Current neurobiology 2019 Wickwire EM, Albrecht JS, Griffin NR, Schnyer DM, Yue JK, Markowitz AJ, Okonkwo DO, Valadka AB, Badjatia N, Manley GT, TRACK-TBI Investigators
• Consensus statement from the International Consensus Meeting on the Role of Decompressive Craniectomy in the Management of Traumatic Brain Injury : Consensus statement.
  Acta neurochirurgica 2019 Hutchinson PJ, Kolias AG, Tajsic T, Adeleye A, Aklilu AT, Apriawan T, Bajamal AH, Barthélemy EJ, Devi BI, Bhat D, Bulters D, Chesnut R, Citerio G, Cooper DJ, Czosnyka M, Edem I, El-Ghandour NMF, …
• Divergent Six Month Functional Recovery Trajectories and Predictors after Traumatic Brain Injury: Novel Insights from the Citicoline Brain Injury Treatment Trial Study.
  Journal of neurotrauma 2019 Gardner RC, Cheng J, Ferguson AR, Boylan R, Boscardin J, Zafonte RD, Manley GT, Citicoline Brain Injury Treatment Trial Investigators
• Diagnosing the GOSE: Structural and Psychometric Properties Using Item Response Theory, a TRACK-TBI Pilot Study.
  Journal of neurotrauma 2019 Ranson J, Magnus BE, Temkin N, Dikmen S, Giacino JT, Okonkwo DO, Valadka AB, Manley GT, Nelson LD, TRACK-TBI Investigators
• Functional Status Examination versus Glasgow Outcome Scale Extended as Outcome Measures in Traumatic Brain Injuries: How Do They Compare?
  Journal of neurotrauma 2019 Dikmen S, Machamer J, Manley GT, Yuh EL, Nelson LD, Temkin NR, TRACK-TBI Investigators
• A Comparison of Satisfaction With Life and the Glasgow Outcome Scale-Extended After Traumatic Brain Injury: An Analysis of the TRACK-TBI Pilot Study.
  The Journal of head trauma rehabilitation 2019 Kreitzer NP, Hart K, Lindsell CJ, Manley GT, Dikmen SS, Ratcliff JJ, Yue JK, Adeoye OM
• The Effect of Goal-Directed Therapy on Patient Morbidity and Mortality After Traumatic Brain Injury: Results From the Progesterone for the Treatment of Traumatic Brain Injury III Clinical Trial.
  Critical care medicine 2019 Merck LH, Yeatts SD, Silbergleit R, Manley GT, Pauls Q, Palesch Y, Conwit R, Le Roux P, Miller J, Frankel M, Wright DW
• Age and sex-mediated differences in six-month outcomes after mild traumatic brain injury in young adults: a TRACK-TBI study.
  Neurological research 2019 Yue JK, Levin HS, Suen CG, Morrissey MR, Runyon SJ, Winkler EA, Puffer RC, Deng H, Robinson CK, Rick JW, Phelps RRL, Sharma S, Taylor SR, Vassar MJ, Cnossen MC, Lingsma HF, Gardner RC, Temkin NR, …
• Pre-injury Comorbidities Are Associated With Functional Impairment and Post-concussive Symptoms at 3- and 6-Months After Mild Traumatic Brain Injury: A TRACK-TBI Study.
  Frontiers in neurology 2019 Yue JK, Cnossen MC, Winkler EA, Deng H, Phelps RRL, Coss NA, Sharma S, Robinson CK, Suen CG, Vassar MJ, Schnyer DM, Puccio AM, Gardner RC, Yuh EL, Mukherjee P, Valadka AB, Okonkwo DO, Lingsma HF, …
• Characterizing the Response to Cerebrospinal Fluid Drainage in Patients with an External Ventricular Drain: The Pressure Equalization Ratio.
  Neurocritical care 2019 Candanedo C, Doron O, Hemphill JC, Ramirez de Noriega F, Manley GT, Patal R, Rosenthal G
• Risk of Posttraumatic Stress Disorder and Major Depression in Civilian Patients After Mild Traumatic Brain Injury: A TRACK-TBI Study.
  JAMA psychiatry 2019 Stein MB, Jain S, Giacino JT, Levin H, Dikmen S, Nelson LD, Vassar MJ, Okonkwo DO, Diaz-Arrastia R, Robertson CS, Mukherjee P, McCrea M, Mac Donald CL, Yue JK, Yuh E, Sun X, Campbell-Sills L, Temkin N…
• The Temporal Relationship of Mental Health Problems and Functional Limitations following mTBI: A TRACK-TBI and TED Study.
  Journal of neurotrauma 2019 Zahniser E, Nelson LD, Dikmen SS, Machamer JE, Stein MB, Yuh E, Manley GT, Temkin NR, TRACK-TBI Investigators
• Rehabilitation Trajectories and Outcomes in Individuals With Mild Traumatic Brain Injury and Psychiatric Histories: A TRACK-TBI Pilot Study.
  The Journal of head trauma rehabilitation 2019 Bertisch H, Satris G, Temkin N, Barber J, Manley GT, Transforming Research and Clinical Knowledge in TBI (TRACK-TBI) Investigators
• Ten-year trends in traumatic brain injury: a retrospective cohort study of California emergency department and hospital revisits and readmissions.
  BMJ open 2018 Hsia RY, Markowitz AJ, Lin F, Guo J, Madhok DY, Manley GT
• A swine model of intracellular cerebral edema - Cerebral physiology and intracranial compliance.
  Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 2018 Ramirez de Noriega F, Manley GT, Moscovici S, Itshayek E, Tamir I, Fellig Y, Shkara RA, Rosenthal G
• Testing a Multivariate Proteomic Panel for Traumatic Brain Injury Biomarker Discovery: A TRACK-TBI Pilot Study.
  Journal of neurotrauma 2018 Huie JR, Diaz-Arrastia R, Yue JK, Sorani MD, Puccio AM, Okonkwo DO, Manley GT, Ferguson AR, TRACK-TBI Investigators
• Temporal lobe contusions on computed tomography are associated with impaired 6-month functional recovery after mild traumatic brain injury: a TRACK-TBI study.
  Neurological research 2018 Yue JK, Winkler EA, Puffer RC, Deng H, Phelps RRL, Wagle S, Morrissey MR, Rivera EJ, Runyon SJ, Vassar MJ, Taylor SR, Cnossen MC, Lingsma HF, Yuh EL, Mukherjee P, Schnyer DM, Puccio AM, Valadka AB, …
• Adult Firearm-Related Traumatic Brain Injury in United States Trauma Centers.
  Journal of neurotrauma 2018 Deng H, Yue JK, Winkler EA, Dhall SS, Manley GT, Tarapore PE
• Sleep, Sleep Disorders, and Circadian Health following Mild Traumatic Brain Injury in Adults: Review and Research Agenda.
  Journal of neurotrauma 2018 Wickwire EM, Schnyer DM, Germain A, Williams SG, Lettieri CJ, McKeon AB, Scharf SM, Stocker R, Albrecht J, Badjatia N, Markowitz AJ, Manley GT
• Travelling waves and tonotopicity in the inner ear: a historical and comparative perspective.
  Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology 2018 Manley GA
• Performance Evaluation of a Multiplex Assay for Simultaneous Detection of Four Clinically Relevant Traumatic Brain Injury Biomarkers.
  Journal of neurotrauma 2018 Korley FK, Yue JK, Wilson DH, Hrusovsky K, Diaz-Arrastia R, Ferguson AR, Yuh EL, Mukherjee P, Wang KKW, Valadka AB, Puccio AM, Okonkwo DO, Manley GT
• Prediction of Persistent Post-Concussion Symptoms after Mild Traumatic Brain Injury.
  Journal of neurotrauma 2018 Cnossen MC, van der Naalt J, Spikman JM, Nieboer D, Yue JK, Winkler EA, Manley GT, von Steinbuechel N, Polinder S, Steyerberg EW, Lingsma HF
• Sub-classifying patients with mild traumatic brain injury: A clustering approach based on baseline clinical characteristics and 90-day and 180-day outcomes.
  PloS one 2018 Si B, Dumkrieger G, Wu T, Zafonte R, Valadka AB, Okonkwo DO, Manley GT, Wang L, Dodick DW, Schwedt TJ, Li J
• Age-Related Differences in Diagnostic Accuracy of Plasma Glial Fibrillary Acidic Protein and Tau for Identifying Acute Intracranial Trauma on Computed Tomography: A TRACK-TBI Study.
  Journal of neurotrauma 2018 Gardner RC, Rubenstein R, Wang KKW, Korley FK, Yue JK, Yuh EL, Mukherje P, Valadka AB, Okonkwo DO, Diaz-Arrastia R, Manley GT
• Predictors of 30-Day Outcomes in Octogenarians with Traumatic C2 Fractures Undergoing Surgery.
  World neurosurgery 2018 Yue JK, Ordaz A, Winkler EA, Deng H, Suen CG, Burke JF, Chan AK, Manley GT, Dhall SS, Tarapore PE
• Concordance of common data elements for assessment of subjective cognitive complaints after mild-traumatic brain injury: a TRACK-TBI Pilot Study.
  Brain injury 2018 Ngwenya LB, Gardner RC, Yue JK, Burke JF, Ferguson AR, Huang MC, Winkler EA, Pirracchio R, Satris GG, Yuh EL, Mukherjee P, Valadka AB, Okonkwo DO, Manley GT
• Motor Evoked Potentials Correlate With Magnetic Resonance Imaging and Early Recovery After Acute Spinal Cord Injury.
  Neurosurgery 2018 Dhall SS, Haefeli J, Talbott JF, Ferguson AR, Readdy WJ, Bresnahan JC, Beattie MS, Pan JZ, Manley GT, Whetstone WD
• Assessment of Follow-up Care After Emergency Department Presentation for Mild Traumatic Brain Injury and Concussion: Results From the TRACK-TBI Study.
  JAMA network open 2018 Seabury SA, Gaudette É, Goldman DP, Markowitz AJ, Brooks J, McCrea MA, Okonkwo DO, Manley GT, TRACK-TBI Investigators, Adeoye O, Badjatia N, Boase K, Bodien Y, Bullock MR, Chesnut R, Corrigan JD, …
• Optimizing Outcome Assessment in Multicenter TBI Trials: Perspectives From TRACK-TBI and the TBI Endpoints Development Initiative.
  The Journal of head trauma rehabilitation 2018 Bodien YG, McCrea M, Dikmen S, Temkin N, Boase K, Machamer J, Taylor SR, Sherer M, Levin H, Kramer JH, Corrigan JD, McAllister TW, Whyte J, Manley GT, Giacino JT, TRACK-TBI Investigators
• Functional Status Examination in Patients with Moderate-to-Severe Traumatic Brain Injuries.
  Journal of neurotrauma 2018 Machamer J, Temkin NR, Manley GT, Dikmen S
• Spontaneous otoacoustic emissions in teiid lizards.
  Hearing research 2018 Manley GA, Wartini A, Schwabedissen G, Siegl E
• Cerebral blood vessel damage in traumatic brain injury.
  Clinical biomechanics (Bristol, Avon) 2018 Monson KL, Converse MI, Manley GT
• Geriatric Traumatic Brain Injury: Epidemiology, Outcomes, Knowledge Gaps, and Future Directions.
  Journal of neurotrauma 2018 Gardner RC, Dams-O'Connor K, Morrissey MR, Manley GT
• The Berlin International Consensus Meeting on Concussion in Sport.
  Neurosurgery 2018 Davis GA, Ellenbogen RG, Bailes J, Cantu RC, Johnston KM, Manley GT, Nagahiro S, Sills A, Tator CH, McCrory P
• An update on diagnostic and prognostic biomarkers for traumatic brain injury.
  Expert review of molecular diagnostics 2018 Wang KK, Yang Z, Zhu T, Shi Y, Rubenstein R, Tyndall JA, Manley GT
• Preinjury employment status as a risk factor for symptomatology and disability in mild traumatic brain injury: A TRACK-TBI analysis.
  NeuroRehabilitation 2018 Yue JK, Rick JW, Morrissey MR, Taylor SR, Deng H, Suen CG, Vassar MJ, Cnossen MC, Lingsma HF, Yuh EL, Mukherjee P, Gardner RC, Valadka AB, Okonkwo DO, Cage TA, Manley GT, TRACK-TBI Investigators
• Safety and effectiveness of early chemical deep venous thrombosis prophylaxis after spinal cord injury: pilot prospective data.
  Neurosurgical focus 2017 DiGiorgio AM, Tsolinas R, Alazzeh M, Haefeli J, Talbott JF, Ferguson AR, Bresnahan JC, Beattie MS, Manley GT, Whetstone WD, Mummaneni PV, Dhall SS
• The diagnostic values of UCH-L1 in traumatic brain injury: A meta-analysis.
  Brain injury 2017 Shahjouei S, Sadeghi-Naini M, Yang Z, Kobeissy F, Rathore D, Shokraneh F, Blackburn S, Manley GT, Wang KKW
• Comparing Plasma Phospho Tau, Total Tau, and Phospho Tau-Total Tau Ratio as Acute and Chronic Traumatic Brain Injury Biomarkers.
  JAMA neurology 2017 Rubenstein R, Chang B, Yue JK, Chiu A, Winkler EA, Puccio AM, Diaz-Arrastia R, Yuh EL, Mukherjee P, Valadka AB, Gordon WA, Okonkwo DO, Davies P, Agarwal S, Lin F, Sarkis G, Yadikar H, Yang Z, Manley …
• Apolipoprotein E epsilon 4 (APOE-ε4) genotype is associated with decreased 6-month verbal memory performance after mild traumatic brain injury.
  Brain and behavior 2017 Yue JK, Robinson CK, Burke JF, Winkler EA, Deng H, Cnossen MC, Lingsma HF, Ferguson AR, McAllister TW, Rosand J, Burchard EG, Sorani MD, Sharma S, Nielson JL, Satris GG, Talbott JF, Tarapore PE, …
• Emergency department blood alcohol level associates with injury factors and six-month outcome after uncomplicated mild traumatic brain injury.
  Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 2017 Yue JK, Ngwenya LB, Upadhyayula PS, Deng H, Winkler EA, Burke JF, Lee YM, Robinson CK, Ferguson AR, Lingsma HF, Cnossen MC, Pirracchio R, Korley FK, Vassar MJ, Yuh EL, Mukherjee P, Gordon WA, Valadka …
• Selective Serotonin Reuptake Inhibitors for Treating Neurocognitive and Neuropsychiatric Disorders Following Traumatic Brain Injury: An Evaluation of Current Evidence.
  Brain sciences 2017 Yue JK, Burke JF, Upadhyayula PS, Winkler EA, Deng H, Robinson CK, Pirracchio R, Suen CG, Sharma S, Ferguson AR, Ngwenya LB, Stein MB, Manley GT, Tarapore PE
• The Traumatic Brain Injury Endpoints Development (TED) Initiative: Progress on a Public-Private Regulatory Collaboration To Accelerate Diagnosis and Treatment of Traumatic Brain Injury.
  Journal of neurotrauma 2017 Manley GT, Mac Donald CL, Markowitz AJ, Stephenson D, Robbins A, Gardner RC, Winkler E, Bodien YG, Taylor SR, Yue JK, Kannan L, Kumar A, McCrea MA, Wang KK, TED Investigators
• Safety and cost efficiency of a restrictive transfusion protocol in patients with traumatic brain injury.
  Journal of neurosurgery 2017 Ngwenya LB, Suen CG, Tarapore PE, Manley GT, Huang MC
• Development of a Prediction Model for Post-Concussive Symptoms following Mild Traumatic Brain Injury: A TRACK-TBI Pilot Study.
  Journal of neurotrauma 2017 Cnossen MC, Winkler EA, Yue JK, Okonkwo DO, Valadka AB, Steyerberg EW, Lingsma HF, Manley GT, TRACK-TBI Investigators
• Morbidity and Mortality Associated with Surgery of Traumatic C2 Fractures in Octogenarians.
  Neurosurgery 2017 Dhall SS, Yue JK, Winkler EA, Mummaneni PV, Manley GT, Tarapore PE
• Prehospital Intubation is Associated with Favorable Outcomes and Lower Mortality in ProTECT III.
  Prehospital emergency care 2017 Denninghoff KR, Nuño T, Pauls Q, Yeatts SD, Silbergleit R, Palesch YY, Merck LH, Manley GT, Wright DW
• Consensus statement on concussion in sport-the 5th international conference on concussion in sport held in Berlin, October 2016.
  British journal of sports medicine 2017 McCrory P, Meeuwisse W, Dvorák J, Aubry M, Bailes J, Broglio S, Cantu RC, Cassidy D, Echemendia RJ, Castellani RJ, Davis GA, Ellenbogen R, Emery C, Engebretsen L, Feddermann-Demont N, Giza CC, …
• Uncovering precision phenotype-biomarker associations in traumatic brain injury using topological data analysis.
  PloS one 2017 Nielson JL, Cooper SR, Yue JK, Sorani MD, Inoue T, Yuh EL, Mukherjee P, Petrossian TC, Paquette J, Lum PY, Carlsson GE, Vassar MJ, Lingsma HF, Gordon WA, Valadka AB, Okonkwo DO, Manley GT, Ferguson AR…
• Resting-State Functional Connectivity Alterations Associated with Six-Month Outcomes in Mild Traumatic Brain Injury.
  Journal of neurotrauma 2017 Palacios EM, Yuh EL, Chang YS, Yue JK, Schnyer DM, Okonkwo DO, Valadka AB, Gordon WA, Maas AIR, Vassar M, Manley GT, Mukherjee P
• Temporal profile of care following mild traumatic brain injury: predictors of hospital admission, follow-up referral and six-month outcome.
  Brain injury 2017 Yue JK, Winkler EA, Sharma S, Vassar MJ, Ratcliff JJ, Korley FK, Seabury SA, Ferguson AR, Lingsma HF, Deng H, Meeuws S, Adeoye OM, Rick JW, Robinson CK, Duarte SM, Yuh EL, Mukherjee P, Dikmen SS, …
• Multivariate Analysis of MRI Biomarkers for Predicting Neurologic Impairment in Cervical Spinal Cord Injury.
  AJNR. American journal of neuroradiology 2016 Haefeli J, Mabray MC, Whetstone WD, Dhall SS, Pan JZ, Upadhyayula P, Manley GT, Bresnahan JC, Beattie MS, Ferguson AR, Talbott JF
• The mammalian Cretaceous cochlear revolution.
  Hearing research 2016 Manley GA
• DRD2 C957T polymorphism is associated with improved 6-month verbal learning following traumatic brain injury.
  Neurogenetics 2016 Yue JK, Winkler EA, Rick JW, Burke JF, McAllister TW, Oh SS, Burchard EG, Hu D, Rosand J, Temkin NR, Korley FK, Sorani MD, Ferguson AR, Lingsma HF, Sharma S, Robinson CK, Yuh EL, Tarapore PE, Wang KK,…
• Failure of Mean Arterial Pressure Goals to Improve Outcomes Following Penetrating Spinal Cord Injury.
  Neurosurgery 2016 Readdy WJ, Saigal R, Whetstone WD, Mefford AN, Ferguson AR, Talbott JF, Inoue T, Bresnahan JC, Beattie MS, Pan J, Manley GT, Dhall SS
• COMT Val158Met polymorphism is associated with post-traumatic stress disorder and functional outcome following mild traumatic brain injury.
  Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 2016 Winkler EA, Yue JK, Ferguson AR, Temkin NR, Stein MB, Barber J, Yuh EL, Sharma S, Satris GG, McAllister TW, Rosand J, Sorani MD, Lingsma HF, Tarapore PE, Burchard EG, Hu D, Eng C, Wang KK, Mukherjee P…
• Circadian variability of the initial Glasgow Coma Scale score in traumatic brain injury patients.
  Neurobiology of sleep and circadian rhythms 2016 Yue JK, Robinson CK, Winkler EA, Upadhyayula PS, Burke JF, Pirracchio R, Suen CG, Deng H, Ngwenya LB, Dhall SS, Manley GT, Tarapore PE
• Advances in Neurotrauma Research.
  Neurosurgery clinics of North America 2016 Vespa PM, Hirt D, Manley GT
• Cerebral Edema in Traumatic Brain Injury: Pathophysiology and Prospective Therapeutic Targets.
  Neurosurgery clinics of North America 2016 Winkler EA, Minter D, Yue JK, Manley GT
• Comparative Auditory Neuroscience: Understanding the Evolution and Function of Ears.
  Journal of the Association for Research in Otolaryngology : JARO 2016 Manley GA
• Brain Tissue Oxygen Monitoring and the Intersection of Brain and Lung: A Comprehensive Review.
  Respiratory care 2016 Ngwenya LB, Burke JF, Manley GT
• Collaborative targeted maximum likelihood estimation for variable importance measure: Illustration for functional outcome prediction in mild traumatic brain injuries.
  Statistical methods in medical research 2016 Pirracchio R, Yue JK, Manley GT, van der Laan MJ, Hubbard AE, TRACK-TBI Investigators including Wayne A Gordon, Hester F Lingsma, Andrew IR Maas, Pratik Mukherjee
• Developing a Cognition Endpoint for Traumatic Brain Injury Clinical Trials.
  Journal of neurotrauma 2016 Silverberg ND, Crane PK, Dams-O'Connor K, Holdnack J, Ivins BJ, Lange RT, Manley GT, McCrea M, Iverson GL
• Screening for Post-Traumatic Stress Disorder in a Civilian Emergency Department Population with Traumatic Brain Injury.
  Journal of neurotrauma 2016 Haarbauer-Krupa J, Taylor CA, Yue JK, Winkler EA, Pirracchio R, Cooper SR, Burke JF, Stein MB, Manley GT
• The acute respiratory distress syndrome following isolated severe traumatic brain injury.
  The journal of trauma and acute care surgery 2016 Hendrickson CM, Howard BM, Kornblith LZ, Conroy AS, Nelson MF, Zhuo H, Liu KD, Manley GT, Matthay MA, Calfee CS, Cohen MJ
• Establishing a Traumatic Brain Injury Program of Care: Benchmarking Outcomes after Institutional Adoption of Evidence-Based Guidelines.
  Journal of neurotrauma 2016 Tarapore PE, Vassar MJ, Cooper S, Lay T, Galletly J, Manley GT, Huang MC
• Frequency selectivity of the human cochlea: Suppression tuning of spontaneous otoacoustic emissions.
  Hearing research 2016 Manley GA, van Dijk P
• A novel antagonist of p75NTR reduces peripheral expansion and CNS trafficking of pro-inflammatory monocytes and spares function after traumatic brain injury.
  Journal of neuroinflammation 2016 Lee S, Mattingly A, Lin A, Sacramento J, Mannent L, Castel MN, Canolle B, Delbary-Gossart S, Ferzaz B, Morganti JM, Rosi S, Ferguson AR, Manley GT, Bresnahan JC, Beattie MS
• A novel inhibitor of p75-neurotrophin receptor improves functional outcomes in two models of traumatic brain injury.
  Brain : a journal of neurology 2016 Delbary-Gossart S, Lee S, Baroni M, Lamarche I, Arnone M, Canolle B, Lin A, Sacramento J, Salegio EA, Castel MN, Delesque-Touchard N, Alam A, Laboudie P, Ferzaz B, Savi P, Herbert JM, Manley GT, …
• Adult sports-related traumatic brain injury in United States trauma centers.
  Neurosurgical focus 2016 Winkler EA, Yue JK, Burke JF, Chan AK, Dhall SS, Berger MS, Manley GT, Tarapore PE
• Pediatric sports-related traumatic brain injury in United States trauma centers.
  Neurosurgical focus 2016 Yue JK, Winkler EA, Burke JF, Chan AK, Dhall SS, Berger MS, Manley GT, Tarapore PE
• Multidimensional Analysis of Magnetic Resonance Imaging Predicts Early Impairment in Thoracic and Thoracolumbar Spinal Cord Injury.
  Journal of neurotrauma 2016 Mabray MC, Talbott JF, Whetstone WD, Dhall SS, Phillips DB, Pan JZ, Manley GT, Bresnahan JC, Beattie MS, Haefeli J, Ferguson AR
• Plasma Anti-Glial Fibrillary Acidic Protein Autoantibody Levels during the Acute and Chronic Phases of Traumatic Brain Injury: A Transforming Research and Clinical Knowledge in Traumatic Brain Injury Pilot Study.
  Journal of neurotrauma 2016 Wang KK, Yang Z, Yue JK, Zhang Z, Winkler EA, Puccio AM, Diaz-Arrastia R, Lingsma HF, Yuh EL, Mukherjee P, Valadka AB, Gordon WA, Okonkwo DO, Manley GT, Cooper SR, Dams-O'Connor K, Hricik AJ, Inoue T,…
• COMT Val 158 Met polymorphism is associated with nonverbal cognition following mild traumatic brain injury.
  Neurogenetics 2015 Winkler EA, Yue JK, McAllister TW, Temkin NR, Oh SS, Burchard EG, Hu D, Ferguson AR, Lingsma HF, Burke JF, Sorani MD, Rosand J, Yuh EL, Barber J, Tarapore PE, Gardner RC, Sharma S, Satris GG, Eng C, …
• Topological data analysis for discovery in preclinical spinal cord injury and traumatic brain injury.
  Nature communications 2015 Nielson JL, Paquette J, Liu AW, Guandique CF, Tovar CA, Inoue T, Irvine KA, Gensel JC, Kloke J, Petrossian TC, Lum PY, Carlsson GE, Manley GT, Young W, Beattie MS, Bresnahan JC, Ferguson AR
• Perioperative morbidity and mortality after lumbar trauma in the elderly.
  Neurosurgical focus 2015 Winkler EA, Yue JK, Birk H, Robinson CK, Manley GT, Dhall SS, Tarapore PE
• A Review of the Effectiveness of Neuroimaging Modalities for the Detection of Traumatic Brain Injury.
  Journal of neurotrauma 2015 Amyot F, Arciniegas DB, Brazaitis MP, Curley KC, Diaz-Arrastia R, Gandjbakhche A, Herscovitch P, Hinds SR, Manley GT, Pacifico A, Razumovsky A, Riley J, Salzer W, Shih R, Smirniotopoulos JG, Stocker D
• Circulating Brain-Derived Neurotrophic Factor Has Diagnostic and Prognostic Value in Traumatic Brain Injury.
  Journal of neurotrauma 2015 Korley FK, Diaz-Arrastia R, Wu AH, Yue JK, Manley GT, Sair HI, Van Eyk J, Everett AD, TRACK-TBI investigators, Okonkwo DO, Valadka AB, Gordon WA, Maas AI, Mukherjee P, Yuh EL, Lingsma HF, Puccio AM, …
• Complications and outcomes of vasopressor usage in acute traumatic central cord syndrome.
  Journal of neurosurgery. Spine 2015 Readdy WJ, Whetstone WD, Ferguson AR, Talbott JF, Inoue T, Saigal R, Bresnahan JC, Beattie MS, Pan JZ, Manley GT, Dhall SS
• The Brain and Spinal Injury Center score: a novel, simple, and reproducible method for assessing the severity of acute cervical spinal cord injury with axial T2-weighted MRI findings.
  Journal of neurosurgery. Spine 2015 Talbott JF, Whetstone WD, Readdy WJ, Ferguson AR, Bresnahan JC, Saigal R, Hawryluk GW, Beattie MS, Mabray MC, Pan JZ, Manley GT, Dhall SS
• Mildly Reduced Brain Swelling and Improved Neurological Outcome in Aquaporin-4 Knockout Mice following Controlled Cortical Impact Brain Injury.
  Journal of neurotrauma 2015 Yao X, Uchida K, Papadopoulos MC, Zador Z, Manley GT, Verkman AS
• Aquaporin-4 regulates the velocity and frequency of cortical spreading depression in mice.
  Glia 2015 Yao X, Smith AJ, Jin BJ, Zador Z, Manley GT, Verkman AS
• Association of a common genetic variant within ANKK1 with six-month cognitive performance after traumatic brain injury.
  Neurogenetics 2015 Yue JK, Pronger AM, Ferguson AR, Temkin NR, Sharma S, Rosand J, Sorani MD, McAllister TW, Barber J, Winkler EA, Burchard EG, Hu D, Lingsma HF, Cooper SR, Puccio AM, Okonkwo DO, Diaz-Arrastia R, Manley…
• Measurement of the glial fibrillary acidic protein and its breakdown products GFAP-BDP biomarker for the detection of traumatic brain injury compared to computed tomography and magnetic resonance imaging.
  Journal of neurotrauma 2015 McMahon PJ, Panczykowski DM, Yue JK, Puccio AM, Inoue T, Sorani MD, Lingsma HF, Maas AI, Valadka AB, Yuh EL, Mukherjee P, Manley GT, Okonkwo DO, TRACK-TBI Investigators
• Classification of traumatic brain injury: past, present, and future.
  Handbook of clinical neurology 2015 Hawryluk GW, Manley GT
• Collaborative European NeuroTrauma Effectiveness Research in Traumatic Brain Injury (CENTER-TBI): a prospective longitudinal observational study.
  Neurosurgery 2015 Maas AI, Menon DK, Steyerberg EW, Citerio G, Lecky F, Manley GT, Hill S, Legrand V, Sorgner A, CENTER-TBI Participants and Investigators
• Genetic data sharing and privacy.
  Neuroinformatics 2015 Sorani MD, Yue JK, Sharma S, Manley GT, Ferguson AR, TRACK TBI Investigators
• Very early administration of progesterone for acute traumatic brain injury.
  The New England journal of medicine 2014 Wright DW, Yeatts SD, Silbergleit R, Palesch YY, Hertzberg VS, Frankel M, Goldstein FC, Caveney AF, Howlett-Smith H, Bengelink EM, Manley GT, Merck LH, Janis LS, Barsan WG, NETT Investigators
• Outcome prediction after mild and complicated mild traumatic brain injury: external validation of existing models and identification of new predictors using the TRACK-TBI pilot study.
  Journal of neurotrauma 2014 Lingsma HF, Yue JK, Maas AI, Steyerberg EW, Manley GT, TRACK-TBI Investigators
• Polyetheretherketone implants for the repair of large cranial defects: a 3-center experience.
  Neurosurgery 2014 Rosenthal G, Ng I, Moscovici S, Lee KK, Lay T, Martin C, Manley GT
• Reduced brain edema and infarct volume in aquaporin-4 deficient mice after transient focal cerebral ischemia.
  Neuroscience letters 2014 Yao X, Derugin N, Manley GT, Verkman AS
• Imaging concussion: a review.
  Neurosurgery 2014 Yuh EL, Hawryluk GW, Manley GT
• Diffusion tensor imaging for outcome prediction in mild traumatic brain injury: a TRACK-TBI study.
  Journal of neurotrauma 2014 Yuh EL, Cooper SR, Mukherjee P, Yue JK, Lingsma HF, Gordon WA, Valadka AB, Okonkwo DO, Schnyer DM, Vassar MJ, Maas AI, Manley GT, TRACK-TBI INVESTIGATORS
• ED disposition of the Glasgow Coma Scale 13 to 15 traumatic brain injury patient: analysis of the Transforming Research and Clinical Knowledge in TBI study.
  The American journal of emergency medicine 2014 Ratcliff JJ, Adeoye O, Lindsell CJ, Hart KW, Pancioli A, McMullan JT, Yue JK, Nishijima DK, Gordon WA, Valadka AB, Okonkwo DO, Lingsma HF, Maas AI, Manley GT, TRACK-TBI investigators
• The emergency department social work intervention for mild traumatic brain injury (SWIFT-Acute): a pilot study.
  Brain injury 2014 Moore M, Winkelman A, Kwong S, Segal SP, Manley GT, Shumway M
• Decompressive craniectomy for acute subdural hematomas.
  Journal of neurosurgery 2014 Kolias AG, Hutchinson PJ, Menon DK, Manley GT, Gallagher CN, Servadei F
• Informatics for neurocritical care: challenges and opportunities.
  Neurocritical care 2014 Sivaganesan A, Manley GT, Huang MC
• Medical and surgical management after spinal cord injury: vasopressor usage, early surgerys, and complications.
  Journal of neurotrauma 2013 Inoue T, Manley GT, Patel N, Whetstone WD
• Symptomatology and functional outcome in mild traumatic brain injury: results from the prospective TRACK-TBI study.
  Journal of neurotrauma 2013 McMahon P, Hricik A, Yue JK, Puccio AM, Inoue T, Lingsma HF, Beers SR, Gordon WA, Valadka AB, Manley GT, Okonkwo DO, TRACK-TBI Investigators
• The impact of previous traumatic brain injury on health and functioning: a TRACK-TBI study.
  Journal of neurotrauma 2013 Dams-O'Connor K, Spielman L, Singh A, Gordon WA, Lingsma HF, Maas AI, Manley GT, Mukherjee P, Okonkwo DO, Puccio AM, Schnyer DM, Valadka AB, Yue JK, Yuh EL, TRACK-TBI Investigators
• Acute biomarkers of traumatic brain injury: relationship between plasma levels of ubiquitin C-terminal hydrolase-L1 and glial fibrillary acidic protein.
  Journal of neurotrauma 2013 Diaz-Arrastia R, Wang KK, Papa L, Sorani MD, Yue JK, Puccio AM, McMahon PJ, Inoue T, Yuh EL, Lingsma HF, Maas AI, Valadka AB, Okonkwo DO, Manley GT, TRACK-TBI Investigators
• Transforming research and clinical knowledge in traumatic brain injury pilot: multicenter implementation of the common data elements for traumatic brain injury.
  Journal of neurotrauma 2013 Yue JK, Vassar MJ, Lingsma HF, Cooper SR, Okonkwo DO, Valadka AB, Gordon WA, Maas AI, Mukherjee P, Yuh EL, Puccio AM, Schnyer DM, Manley GT, TRACK-TBI Investigators
• Traumatic brain injury: an international knowledge-based approach.
  JAMA 2013 Manley GT, Maas AI
• GFAP-BDP as an acute diagnostic marker in traumatic brain injury: results from the prospective transforming research and clinical knowledge in traumatic brain injury study.
  Journal of neurotrauma 2013 Okonkwo DO, Yue JK, Puccio AM, Panczykowski DM, Inoue T, McMahon PJ, Sorani MD, Yuh EL, Lingsma HF, Maas AI, Valadka AB, Manley GT, Transforming Research and Clinical Knowledge in Traumatic Brain …
• Military risk factors for Alzheimer's disease.
  Alzheimer's & dementia : the journal of the Alzheimer's Association 2013 Weiner MW, Friedl KE, Pacifico A, Chapman JC, Jaffee MS, Little DM, Manley GT, McKee A, Petersen RC, Pitman RK, Yaffe K, Zetterberg H, Obana R, Bain LJ, Carrillo MC
• Combined SCI and TBI: recovery of forelimb function after unilateral cervical spinal cord injury (SCI) is retarded by contralateral traumatic brain injury (TBI), and ipsilateral TBI balances the effects of SCI on paw placement.
  Experimental neurology 2013 Inoue T, Lin A, Ma X, McKenna SL, Creasey GH, Manley GT, Ferguson AR, Bresnahan JC, Beattie MS
• Altering physiological networks using drugs: steps towards personalized physiology.
  BMC medical genomics 2013 Grossman AD, Cohen MJ, Manley GT, Butte AJ
• Resting state magnetoencephalography functional connectivity in traumatic brain injury.
  Journal of neurosurgery 2013 Tarapore PE, Findlay AM, Lahue SC, Lee H, Honma SM, Mizuiri D, Luks TL, Manley GT, Nagarajan SS, Mukherjee P
• Mosaic evolution of the mammalian auditory periphery.
  Advances in experimental medicine and biology 2013 Manley GA
• Magnetic resonance imaging improves 3-month outcome prediction in mild traumatic brain injury.
  Annals of neurology 2012 Yuh EL, Mukherjee P, Lingsma HF, Yue JK, Ferguson AR, Gordon WA, Valadka AB, Schnyer DM, Okonkwo DO, Maas AI, Manley GT, TRACK-TBI Investigators
• Early management of severe traumatic brain injury.
  Lancet (London, England) 2012 Rosenfeld JV, Maas AI, Bragge P, Morganti-Kossmann MC, Manley GT, Gruen RL
• A longitudinal MRI study of traumatic axonal injury in patients with moderate and severe traumatic brain injury.
  Journal of neurology, neurosurgery, and psychiatry 2012 Moen KG, Skandsen T, Folvik M, Brezova V, Kvistad KA, Rydland J, Manley GT, Vik A
• Coagulopathy after traumatic brain injury.
  Neurosurgery 2012 Laroche M, Kutcher ME, Huang MC, Cohen MJ, Manley GT
• Quantitative CT improves outcome prediction in acute traumatic brain injury.
  Journal of neurotrauma 2011 Yuh EL, Cooper SR, Ferguson AR, Manley GT
• Re-orientation of clinical research in traumatic brain injury: report of an international workshop on comparative effectiveness research.
  Journal of neurotrauma 2011 Maas AI, Menon DK, Lingsma HF, Pineda JA, Sandel ME, Manley GT
• The effect of decompressive hemicraniectomy on brain temperature after severe brain injury.
  Neurocritical care 2011 Nakagawa K, Hills NK, Kamel H, Patel PV, Manley GT, Hemphill JC
• Marked reduction in wound complication rates following decompressive hemicraniectomy with an improved operative closure technique.
  Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 2011 Sughrue ME, Bloch OG, Manley GT, Stiver SI
• Temporizing treatment of hyperacute subdural hemorrhage by subdural evacuation port system placement.
  Journal of neurosurgery 2011 Flint AC, Gean AD, Manley GT, Rao VA, Sheridan WF, von Koch CS
• Mechanisms of primary blast-induced traumatic brain injury: insights from shock-wave research.
  Journal of neurotrauma 2011 Nakagawa A, Manley GT, Gean AD, Ohtani K, Armonda R, Tsukamoto A, Yamamoto H, Takayama K, Tominaga T
• Tight squeeze, slow burn: inflammation and the aetiology of cervical myelopathy.
  Brain : a journal of neurology 2011 Beattie MS, Manley GT
• Dynamic, multi-level network models of clinical trials.
  Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing 2011 Sorani MD, Manley GT, Claude Hemphill J, Baranzini SE
• Common data elements for research on traumatic brain injury and psychological health: current status and future development.
  Archives of physical medicine and rehabilitation 2010 Whyte J, Vasterling J, Manley GT
• Common data elements for traumatic brain injury: recommendations from the biospecimens and biomarkers working group.
  Archives of physical medicine and rehabilitation 2010 Manley GT, Diaz-Arrastia R, Brophy M, Engel D, Goodman C, Gwinn K, Veenstra TD, Ling G, Ottens AK, Tortella F, Hayes RL
• Hemicraniectomy: a new model for human electrophysiology with high spatio-temporal resolution.
  Journal of cognitive neuroscience 2010 Voytek B, Secundo L, Bidet-Caulet A, Scabini D, Stiver SI, Gean AD, Manley GT, Knight RT
• Abrupt increase in rat carotid blood flow induces rapid alteration of artery mechanical properties.
  Journal of the mechanical behavior of biomedical materials 2010 Monson KL, Matsumoto MM, Young WL, Manley GT, Hashimoto T
• Benign anterior temporal epidural hematoma: indolent lesion with a characteristic CT imaging appearance after blunt head trauma.
  Radiology 2010 Gean AD, Fischbein NJ, Purcell DD, Aiken AH, Manley GT, Stiver SI
• Incorporating a parenchymal thermal diffusion cerebral blood flow probe in bedside assessment of cerebral autoregulation and vasoreactivity in patients with severe traumatic brain injury.
  Journal of neurosurgery 2010 Rosenthal G, Sanchez-Mejia RO, Phan N, Hemphill JC, Martin C, Manley GT
• Identification of complex metabolic states in critically injured patients using bioinformatic cluster analysis.
  Critical care (London, England) 2010 Cohen MJ, Grossman AD, Morabito D, Knudson MM, Butte AJ, Manley GT
• Interobserver variability in the assessment of CT imaging features of traumatic brain injury.
  Journal of neurotrauma 2010 Chun KA, Manley GT, Stiver SI, Aiken AH, Phan N, Wang V, Meeker M, Cheng SC, Gean AD, Wintermark M
• Clinical trials in traumatic brain injury: past experience and current developments.
  Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 2010 Maas AI, Roozenbeek B, Manley GT
• Infection in the intensive care unit alters physiological networks.
  BMC bioinformatics 2009 Grossman AD, Cohen MJ, Manley GT, Butte AJ
• Race\ethnicity and outcome after traumatic brain injury at a single, diverse center.
  The Journal of trauma 2009 Sorani MD, Lee M, Kim H, Meeker M, Manley GT
• Introduction: decompressive craniectomy for trauma and cerebrovascular disease.
  Neurosurgical focus 2009 Manley GT
• Survival with good outcome after cerebral herniation and Duret hemorrhage caused by traumatic brain injury.
  Journal of neurosurgery 2009 Stiver SI, Gean AD, Manley GT
• Effects of white, grey, and pia mater properties on tissue level stresses and strains in the compressed spinal cord.
  Journal of neurotrauma 2009 Sparrey CJ, Manley GT, Keaveny TM
• Refining resuscitation strategies using tissue oxygen and perfusion monitoring in critical organ beds.
  The Journal of trauma 2009 Wan JJ, Cohen MJ, Rosenthal G, Haitsma IK, Morabito DJ, Derugin N, Knudson MM, Manley GT
• Role of aquaporin-4 in cerebral edema and stroke.
  Handbook of experimental pharmacology 2009 Zador Z, Stiver S, Wang V, Manley GT
• The new Licox combined brain tissue oxygen and brain temperature monitor: assessment of in vitro accuracy and clinical experience in severe traumatic brain injury.
  Neurosurgery 2008 Stewart C, Haitsma I, Zador Z, Hemphill JC, Morabito D, Manley G, Rosenthal G
• Structural dissociation of attentional control and memory in adults with and without mild traumatic brain injury.
  Brain : a journal of neurology 2008 Niogi SN, Mukherjee P, Ghajar J, Johnson CE, Kolster R, Lee H, Suh M, Zimmerman RD, Manley GT, McCandliss BD
• Biaxial response of passive human cerebral arteries.
  Annals of biomedical engineering 2008 Monson KL, Barbaro NM, Manley GT
• Computer-aided assessment of head computed tomography (CT) studies in patients with suspected traumatic brain injury.
  Journal of neurotrauma 2008 Yuh EL, Gean AD, Manley GT, Callen AL, Wintermark M
• Prehospital management of traumatic brain injury.
  Neurosurgical focus 2008 Stiver SI, Manley GT
• Relationship of "dose" of intracranial hypertension to outcome in severe traumatic brain injury.
  Journal of neurosurgery 2008 Vik A, Nag T, Fredriksli OA, Skandsen T, Moen KG, Schirmer-Mikalsen K, Manley GT
• Focal lesions in acute mild traumatic brain injury and neurocognitive outcome: CT versus 3T MRI.
  Journal of neurotrauma 2008 Lee H, Wintermark M, Gean AD, Ghajar J, Manley GT, Mukherjee P
• Genetic variation in human aquaporins and effects on phenotypes of water homeostasis.
  Human mutation 2008 Sorani MD, Manley GT, Giacomini KM
• Reversible monoparesis following decompressive hemicraniectomy for traumatic brain injury.
  Journal of neurosurgery 2008 Stiver SI, Wintermark M, Manley GT
• Classification of traumatic brain injury for targeted therapies.
  Journal of neurotrauma 2008 Saatman KE, Duhaime AC, Bullock R, Maas AI, Valadka A, Manley GT, Workshop Scientific Team and Advisory Panel Members
• Brain tissue oxygen tension is more indicative of oxygen diffusion than oxygen delivery and metabolism in patients with traumatic brain injury.
  Critical care medicine 2008 Rosenthal G, Hemphill JC, Sorani M, Martin C, Morabito D, Obrist WD, Manley GT
• Novel variants in human Aquaporin-4 reduce cellular water permeability.
  Human molecular genetics 2008 Sorani MD, Zador Z, Hurowitz E, Yan D, Giacomini KM, Manley GT
• Aquaporin-4-deficient mice have increased extracellular space without tortuosity change.
  The Journal of neuroscience : the official journal of the Society for Neuroscience 2008 Yao X, Hrabetová S, Nicholson C, Manley GT
• Post-operative expansion of hemorrhagic contusions after unilateral decompressive hemicraniectomy in severe traumatic brain injury.
  Journal of neurotrauma 2008 Flint AC, Manley GT, Gean AD, Hemphill JC, Rosenthal G
• Characterizing the dose-response relationship between mannitol and intracranial pressure in traumatic brain injury patients using a high-frequency physiological data collection system.
  Journal of neurotrauma 2008 Sorani MD, Morabito D, Rosenthal G, Giacomini KM, Manley GT
• Cerebral salt wasting and elevated brain natriuretic peptide levels after traumatic brain injury: 2 case reports.
  Surgical neurology 2008 Lu DC, Binder DK, Chien B, Maisel A, Manley GT
• Use of hemoglobin-based oxygen-carrying solution-201 to improve resuscitation parameters and prevent secondary brain injury in a swine model of traumatic brain injury and hemorrhage: laboratory investigation.
  Journal of neurosurgery 2008 Rosenthal G, Morabito D, Cohen M, Roeytenberg A, Derugin N, Panter SS, Knudson MM, Manley G
• Extent of microstructural white matter injury in postconcussive syndrome correlates with impaired cognitive reaction time: a 3T diffusion tensor imaging study of mild traumatic brain injury.
  AJNR. American journal of neuroradiology 2008 Niogi SN, Mukherjee P, Ghajar J, Johnson C, Kolster RA, Sarkar R, Lee H, Meeker M, Zimmerman RD, Manley GT, McCandliss BD
• Recognition of paroxysmal autonomic instability with dystonia (PAID) in a patient with traumatic brain injury.
  The Journal of trauma 2008 Wang VY, Manley G
• Dose-response relationship of mannitol and intracranial pressure: a metaanalysis.
  Journal of neurosurgery 2008 Sorani MD, Manley GT
• In vitro comparison of two generations of Licox and Neurotrend catheters.
  Acta neurochirurgica. Supplement 2008 Haitsma I, Rosenthal G, Morabito D, Rollins M, Maas AI, Manley GT
• Motor trephine syndrome: a mechanistic hypothesis.
  Acta neurochirurgica. Supplement 2008 Stiver SI, Wintermark M, Manley GT
• Predictive values of age and the Glasgow Coma Scale in traumatic brain injury patients treated with decompressive craniectomy.
  Acta neurochirurgica. Supplement 2008 Potts MB, Chi JH, Meeker M, Holland MC, Claude HJ, Manley GT
• The role of lung function in brain tissue oxygenation following traumatic brain injury.
  Journal of neurosurgery 2008 Rosenthal G, Hemphill JC, Sorani M, Martin C, Morabito D, Meeker M, Wang V, Manley GT
• Early coagulopathy after traumatic brain injury: the role of hypoperfusion and the protein C pathway.
  The Journal of trauma 2007 Cohen MJ, Brohi K, Ganter MT, Manley GT, Mackersie RC, Pittet JF
• Microfiberoptic fluorescence photobleaching reveals size-dependent macromolecule diffusion in extracellular space deep in brain.
  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2007 Zador Z, Magzoub M, Jin S, Manley GT, Papadopoulos MC, Verkman AS
• The role of early follow-up computed tomography imaging in the management of traumatic brain injury patients with intracranial hemorrhage.
  The Journal of trauma 2007 Smith JS, Chang EF, Rosenthal G, Meeker M, von Koch C, Manley GT, Holland MC
• Emergent placement of halo orthosis after a traumatic cervical injury leading to a cerebral abscess.
  The Journal of trauma 2007 Quiñones-Hinojosa A, Chi JH, Manley GT
• The role of aquaporin-4 in cerebral water transport and edema.
  Neurosurgical focus 2007 Bloch O, Manley GT
• Aquaporins: role in cerebral edema and brain water balance.
  Progress in brain research 2007 Zador Z, Bloch O, Yao X, Manley GT
• Guidelines for the management of severe traumatic brain injury. I. Blood pressure and oxygenation.
  Journal of neurotrauma 2007 Brain Trauma Foundation, American Association of Neurological Surgeons, Congress of Neurological Surgeons, Joint Section on Neurotrauma and Critical Care, AANS/CNS, Bratton SL, Chestnut RM, Ghajar J, …
• Guidelines for the management of severe traumatic brain injury. II. Hyperosmolar therapy.
  Journal of neurotrauma 2007 Brain Trauma Foundation, American Association of Neurological Surgeons, Congress of Neurological Surgeons, Joint Section on Neurotrauma and Critical Care, AANS/CNS, Bratton SL, Chestnut RM, Ghajar J, …
• Guidelines for the management of severe traumatic brain injury. III. Prophylactic hypothermia.
  Journal of neurotrauma 2007 Brain Trauma Foundation, American Association of Neurological Surgeons, Congress of Neurological Surgeons, Joint Section on Neurotrauma and Critical Care, AANS/CNS, Bratton SL, Chestnut RM, Ghajar J, …
• Guidelines for the management of severe traumatic brain injury. IV. Infection prophylaxis.
  Journal of neurotrauma 2007 Brain Trauma Foundation, American Association of Neurological Surgeons, Congress of Neurological Surgeons, Joint Section on Neurotrauma and Critical Care, AANS/CNS, Bratton SL, Chestnut RM, Ghajar J, …
• Guidelines for the management of severe traumatic brain injury. IX. Cerebral perfusion thresholds.
  Journal of neurotrauma 2007 Brain Trauma Foundation, American Association of Neurological Surgeons, Congress of Neurological Surgeons, Joint Section on Neurotrauma and Critical Care, AANS/CNS, Bratton SL, Chestnut RM, Ghajar J, …
• Guidelines for the management of severe traumatic brain injury. V. Deep vein thrombosis prophylaxis.
  Journal of neurotrauma 2007 Brain Trauma Foundation, American Association of Neurological Surgeons, Congress of Neurological Surgeons, Joint Section on Neurotrauma and Critical Care, AANS/CNS, Bratton SL, Chestnut RM, Ghajar J, …
• Guidelines for the management of severe traumatic brain injury. VI. Indications for intracranial pressure monitoring.
  Journal of neurotrauma 2007 Brain Trauma Foundation, American Association of Neurological Surgeons, Congress of Neurological Surgeons, Joint Section on Neurotrauma and Critical Care, AANS/CNS, Bratton SL, Chestnut RM, Ghajar J, …
• Guidelines for the management of severe traumatic brain injury. VII. Intracranial pressure monitoring technology.
  Journal of neurotrauma 2007 Brain Trauma Foundation, American Association of Neurological Surgeons, Congress of Neurological Surgeons, Joint Section on Neurotrauma and Critical Care, AANS/CNS, Bratton SL, Chestnut RM, Ghajar J, …
• Guidelines for the management of severe traumatic brain injury. VIII. Intracranial pressure thresholds.
  Journal of neurotrauma 2007 Brain Trauma Foundation, American Association of Neurological Surgeons, Congress of Neurological Surgeons, Joint Section on Neurotrauma and Critical Care, AANS/CNS, Bratton SL, Chestnut RM, Ghajar J, …
• Guidelines for the management of severe traumatic brain injury. X. Brain oxygen monitoring and thresholds.
  Journal of neurotrauma 2007 Brain Trauma Foundation, American Association of Neurological Surgeons, Congress of Neurological Surgeons, Joint Section on Neurotrauma and Critical Care, AANS/CNS, Bratton SL, Chestnut RM, Ghajar J, …
• Guidelines for the management of severe traumatic brain injury. XI. Anesthetics, analgesics, and sedatives.
  Journal of neurotrauma 2007 Brain Trauma Foundation, American Association of Neurological Surgeons, Congress of Neurological Surgeons, Joint Section on Neurotrauma and Critical Care, AANS/CNS, Bratton SL, Chestnut RM, Ghajar J, …
• Guidelines for the management of severe traumatic brain injury. XII. Nutrition.
  Journal of neurotrauma 2007 Brain Trauma Foundation, American Association of Neurological Surgeons, Congress of Neurological Surgeons, Joint Section on Neurotrauma and Critical Care, AANS/CNS, Bratton SL, Chestnut RM, Ghajar J, …
• Guidelines for the management of severe traumatic brain injury. XIII. Antiseizure prophylaxis.
  Journal of neurotrauma 2007 Brain Trauma Foundation, American Association of Neurological Surgeons, Congress of Neurological Surgeons, Joint Section on Neurotrauma and Critical Care, AANS/CNS, Bratton SL, Chestnut RM, Ghajar J, …
• Guidelines for the management of severe traumatic brain injury. XIV. Hyperventilation.
  Journal of neurotrauma 2007 Brain Trauma Foundation, American Association of Neurological Surgeons, Congress of Neurological Surgeons, Joint Section on Neurotrauma and Critical Care, AANS/CNS, Bratton SL, Chestnut RM, Ghajar J, …
• Guidelines for the management of severe traumatic brain injury. XV. Steroids.
  Journal of neurotrauma 2007 Brain Trauma Foundation, American Association of Neurological Surgeons, Congress of Neurological Surgeons, Joint Section on Neurotrauma and Critical Care, AANS/CNS, Bratton SL, Chestnut RM, Ghajar J, …
• New approaches to physiological informatics in neurocritical care.
  Neurocritical care 2007 Sorani MD, Hemphill JC, Morabito D, Rosenthal G, Manley GT
• Greatly impaired migration of implanted aquaporin-4-deficient astroglial cells in mouse brain toward a site of injury.
  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2006 Auguste KI, Jin S, Uchida K, Yan D, Manley GT, Papadopoulos MC, Verkman AS
• Prehospital hypoxia affects outcome in patients with traumatic brain injury: a prospective multicenter study.
  The Journal of trauma 2006 Chi JH, Knudson MM, Vassar MJ, McCarthy MC, Shapiro MB, Mallet S, Holcroft JJ, Moncrief H, Noble J, Wisner D, Kaups KL, Bennick LD, Manley GT
• Continuous muscle tissue oxygenation in critically injured patients: a prospective observational study.
  The Journal of trauma 2006 Ikossi DG, Knudson MM, Morabito DJ, Cohen MJ, Wan JJ, Khaw L, Stewart CJ, Hemphill C, Manley GT
• Increased seizure duration and slowed potassium kinetics in mice lacking aquaporin-4 water channels.
  Glia 2006 Binder DK, Yao X, Zador Z, Sick TJ, Verkman AS, Manley GT
• Accelerated progression of kaolin-induced hydrocephalus in aquaporin-4-deficient mice.
  Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2006 Bloch O, Auguste KI, Manley GT, Verkman AS
• Controlled cortical impact in swine: pathophysiology and biomechanics.
  Journal of neurotrauma 2006 Manley GT, Rosenthal G, Lam M, Morabito D, Yan D, Derugin N, Bollen A, Knudson MM, Panter SS
• Impaired pain sensation in mice lacking Aquaporin-1 water channels.
  Biochemical and biophysical research communications 2006 Oshio K, Watanabe H, Yan D, Verkman AS, Manley GT
• Increased seizure duration in mice lacking aquaporin-4 water channels.
  Acta neurochirurgica. Supplement 2006 Binder DK, Yao X, Verkman AS, Manley GT
• Recovery at one year following isolated traumatic brain injury: a Western Trauma Association prospective multicenter trial.
  The Journal of trauma 2005 Livingston DH, Lavery RF, Mosenthal AC, Knudson MM, Lee S, Morabito D, Manley GT, Nathens A, Jurkovich G, Hoyt DB, Coimbra R
• Involvement of aquaporin-4 in astroglial cell migration and glial scar formation.
  Journal of cell science 2005 Saadoun S, Papadopoulos MC, Watanabe H, Yan D, Manley GT, Verkman AS
• K+ waves in brain cortex visualized using a long-wavelength K+-sensing fluorescent indicator.
  Nature methods 2005 Padmawar P, Yao X, Bloch O, Manley GT, Verkman AS
• Aquaporin-4 gene deletion in mice increases focal edema associated with staphylococcal brain abscess.
  Journal of neurochemistry 2005 Bloch O, Papadopoulos MC, Manley GT, Verkman AS
• Effects of 23.4% sodium chloride solution in reducing intracranial pressure in patients with traumatic brain injury: a preliminary study.
  Neurosurgery 2005 Ware ML, Nemani VM, Meeker M, Lee C, Morabito DJ, Manley GT
• Pregnancy-related vertebral hemangioma. Case report, review of the literature, and management algorithm.
  Neurosurgical focus 2005 Chi JH, Manley GT, Chou D
• Airbag deployment and improperly restrained children: a lethal combination.
  The Journal of trauma 2005 Quiñones-Hinojosa A, Jun P, Manley GT, Knudson MM, Gupta N
• Evaluation of the portable infrared pupillometer.
  Neurosurgery 2005 Du R, Meeker M, Bacchetti P, Larson MD, Holland MC, Manley GT
• Relationship between brain tissue oxygen tension and CT perfusion: feasibility and initial results.
  AJNR. American journal of neuroradiology 2005 Hemphill JC, Smith WS, Sonne DC, Morabito D, Manley GT
• Influence of data resolution and interpolation method on assessment of secondary brain insults in neurocritical care.
  Physiological measurement 2005 Hemphill JC, Barton CW, Morabito D, Manley GT
• Significance of source and size in the mechanical response of human cerebral blood vessels.
  Journal of biomechanics 2005 Monson KL, Goldsmith W, Barbaro NM, Manley GT
• Expression of the aquaporin-1 water channel in human glial tumors.
  Neurosurgery 2005 Oshio K, Binder DK, Liang Y, Bollen A, Feuerstein B, Berger MS, Manley GT
• Pupil examination: validity and clinical utility of an automated pupillometer.
  The Journal of neuroscience nursing : journal of the American Association of Neuroscience Nurses 2005 Meeker M, Du R, Bacchetti P, Privitera CM, Larson MD, Holland MC, Manley G
• A novel method of evaluating the impact of secondary brain insults on functional outcomes in traumatic brain-injured patients.
  Academic emergency medicine : official journal of the Society for Academic Emergency Medicine 2005 Barton CW, Hemphill JC, Morabito D, Manley G
• Brain tissue oxygen monitoring in intracerebral hemorrhage.
  Neurocritical care 2005 Hemphill JC, Morabito D, Farrant M, Manley GT
• Diffusion Tensor Imaging with Three-dimensional Fiber Tractography of Traumatic Axonal Shearing Injury: An Imaging Correlate for the Posterior Callosal "Disconnection" Syndrome: Case Report.
  Neurosurgery 2005 Le TH, Mukherjee P, Henry RG, Berman JI, Ware M, Manley GT
• Diffusion tensor imaging with three-dimensional fiber tractography of traumatic axonal shearing injury: an imaging correlate for the posterior callosal "disconnection" syndrome: case report.
  Neurosurgery 2005 Le TH, Mukherjee P, Henry RG, Berman JI, Ware M, Manley GT
• Reduced cerebrospinal fluid production and intracranial pressure in mice lacking choroid plexus water channel Aquaporin-1.
  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2004 Oshio K, Watanabe H, Song Y, Verkman AS, Manley GT
• Aquaporin-4 facilitates reabsorption of excess fluid in vasogenic brain edema.
  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2004 Papadopoulos MC, Manley GT, Krishna S, Verkman AS
• The effect of age on functional outcome in mild traumatic brain injury: 6-month report of a prospective multicenter trial.
  The Journal of trauma 2004 Mosenthal AC, Livingston DH, Lavery RF, Knudson MM, Lee S, Morabito D, Manley GT, Nathens A, Jurkovich G, Hoyt DB, Coimbra R
• Volumetric proton spectroscopic imaging of mild traumatic brain injury.
  AJNR. American journal of neuroradiology 2004 Govindaraju V, Gauger GE, Manley GT, Ebel A, Meeker M, Maudsley AA
• Transcranial motor evoked potential recording in a case of Kernohan's notch syndrome: case report.
  Neurosurgery 2004 Binder DK, Lyon R, Manley GT
• Increased seizure threshold in mice lacking aquaporin-4 water channels.
  Neuroreport 2004 Binder DK, Oshio K, Ma T, Verkman AS, Manley GT
• Diagnosis of posttraumatic transverse sinus thrombosis with magnetic resonance imaging/magnetic resonance venography: report of two cases.
  The Journal of trauma 2004 Quiñones-Hinojosa A, Binder DK, Hemphill JC, Manley GT
• Expression of aquaporin water channels in mouse spinal cord.
  Neuroscience 2004 Oshio K, Binder DK, Yang B, Schecter S, Verkman AS, Manley GT
• Molecular mechanisms of brain tumor edema.
  Neuroscience 2004 Papadopoulos MC, Saadoun S, Binder DK, Manley GT, Krishna S, Verkman AS
• New insights into water transport and edema in the central nervous system from phenotype analysis of aquaporin-4 null mice.
  Neuroscience 2004 Manley GT, Binder DK, Papadopoulos MC, Verkman AS
• Sevenfold-reduced osmotic water permeability in primary astrocyte cultures from AQP-4-deficient mice, measured by a fluorescence quenching method.
  American journal of physiology. Cell physiology 2003 Solenov E, Watanabe H, Manley GT, Verkman AS
• Axial mechanical properties of fresh human cerebral blood vessels.
  Journal of biomechanical engineering 2003 Monson KL, Goldsmith W, Barbaro NM, Manley GT
• Ruptured posterior communicating artery aneurysm presenting as acute subdural hematoma.
  The American journal of emergency medicine 2003 Tsao JW, Waldman JL, Manley GT
• Tissue oxygen monitoring during hemorrhagic shock and resuscitation: a comparison of lactated Ringer's solution, hypertonic saline dextran, and HBOC-201.
  The Journal of trauma 2003 Knudson MM, Lee S, Erickson V, Morabito D, Derugin N, Manley GT
• Aquaporin-1 deletion reduces osmotic water permeability and cerebrospinal fluid production.
  Acta neurochirurgica. Supplement 2003 Oshio K, Song Y, Verkman AS, Manley GT
• Aquaporin-1 expression in human glial tumors suggests a potential novel therapeutic target for tumor-associated edema.
  Acta neurochirurgica. Supplement 2003 Oshio K, Binder DK, Bollen A, Verkman AS, Berger MS, Manley GT
• Small-volume resuscitation with the hemoglobin substitute HBOC-201: effect on brain tissue oxygenation.
  Advances in experimental medicine and biology 2003 Manley GT, Hemphill JC, Morabito D, Erickson V, Holcroft JJ, Derugin N, Knudson MM
• Computational study of the contribution of the vasculature on the dynamic response of the brain.
  Stapp car crash journal 2002 Zhang L, Bae J, Hardy WN, Monson KL, Manley GT, Goldsmith W, Yang KH, King AI
• Small-volume resuscitation with HBOC-201: effects on cardiovascular parameters and brain tissue oxygen tension in an out-of-hospital model of hemorrhage in swine.
  Academic emergency medicine : official journal of the Society for Academic Emergency Medicine 2002 Lee SK, Morabito D, Hemphill JC, Erickson V, Holcroft JJ, Derugin N, Knudson MM, Manley GT
• Infrared pupillometry during uncal herniation.
  Journal of neurosurgical anesthesiology 2002 Manley GT, Larson MD
• Optical measurement of swelling and water transport in spinal cord slices from aquaporin null mice.
  Journal of neuroscience methods 2002 Solenov EI, Vetrivel L, Oshio K, Manley GT, Verkman AS
• Hypotension, hypoxia, and head injury: frequency, duration, and consequences.
  Archives of surgery (Chicago, Ill. : 1960) 2001 Manley G, Knudson MM, Morabito D, Damron S, Erickson V, Pitts L
• The ICH score: a simple, reliable grading scale for intracerebral hemorrhage.
  Stroke 2001 Hemphill JC, Bonovich DC, Besmertis L, Manley GT, Johnston SC
• Cerebral oxygenation during hemorrhagic shock: perils of hyperventilation and the therapeutic potential of hypoventilation.
  The Journal of trauma 2000 Manley GT, Hemphill JC, Morabito D, Derugin N, Erickson V, Pitts LH, Knudson MM
• Skeletal muscle function and water permeability in aquaporin-4 deficient mice.
  American journal of physiology. Cell physiology 2000 Yang B, Verbavatz JM, Song Y, Vetrivel L, Manley G, Kao WM, Ma T, Verkman AS
• Acute posterior fossa syndrome following lumbar drainage for treatment of suboccipital pseudomeningocele. Report of three cases.
  Journal of neurosurgery 2000 Manley GT, Dillon W
• Role of water channels in fluid transport studied by phenotype analysis of aquaporin knockout mice.
  Experimental physiology 2000 Verkman AS, Yang B, Song Y, Manley GT, Ma T
• Aquaporin-4 deletion in mice reduces brain edema after acute water intoxication and ischemic stroke.
  Nature medicine 2000 Manley GT, Fujimura M, Ma T, Noshita N, Filiz F, Bollen AW, Chan P, Verkman AS
• Brain tissue oxygenation during hemorrhagic shock, resuscitation, and alterations in ventilation.
  The Journal of trauma 1999 Manley GT, Pitts LH, Morabito D, Doyle CA, Gibson J, Gimbel M, Hopf HW, Knudson MM
• Detection of Bartonella henselae by polymerase chain reaction in brain tissue of an immunocompromised patient with multiple enhancing lesions. Case report and review of the literature.
  Journal of neurosurgery 1998 George TI, Manley G, Koehler JE, Hung VS, McDermott M, Bollen A
• Immunization with the paraneoplastic encephalomyelitis antigen HuD does not cause neurologic disease in mice.
  Neurology 1995 Sillevis Smitt PA, Manley GT, Posner JB
• Inhibition of proliferation and induction of differentiation in medulloblastoma- and astrocytoma-derived cell lines with phenylacetate.
  Journal of neurosurgery 1995 Stockhammer G, Manley GT, Johnson R, Rosenblum MK, Samid D, Lieberman FS