Gabe Ortiz, MD, PhD
Professor
Medicine
School of Medicine

He is deeply engaged in applying Toyota's LEAN production and LEAN daily management systems as tools for achieving healthcare systems transformation (see links below for more information). Dr. Ortiz is also engaged in the implementation and optimization of Epic, the new enterprise EHR at ZSFG.

• Tracheal aspirate RNA sequencing identifies distinct immunological features of COVID-19 ARDS.
  Nature communications 2021 Sarma A, Christenson SA, Byrne A, Mick E, Pisco AO, DeVoe C, Deiss T, Ghale R, Zha BS, Tsitsiklis A, Jauregui A, Moazed F, Detweiler AM, Spottiswoode N, Sinha P, Neff N, Tan M, Serpa PH, Willmore A, …
• Type I interferon autoantibodies are associated with systemic immune alterations in patients with COVID-19.
  Science translational medicine 2021 van der Wijst MGP, Vazquez SE, Hartoularos GC, Bastard P, Grant T, Bueno R, Lee DS, Greenland JR, Sun Y, Perez R, Ogorodnikov A, Ward A, Mann SA, Lynch KL, Yun C, Havlir DV, Chamie G, Marquez C, …
• Longitudinal single-cell epitope and RNA-sequencing reveals the immunological impact of type 1 interferon autoantibodies in critical COVID-19: Anti-IFN antibodies in critical COVID-19 correlate with poor ISG response and upregulation of LAIR1 surface protein in PBMCs.
  bioRxiv : the preprint server for biology 2021 van der Wijst MGP, Vazquez SE, Hartoularos GC, Bastard P, Grant T, Bueno R, Lee DS, Greenland JR, Sun Y, Perez R, Ogorodnikov A, Ward A, Mann SA, Lynch KL, Yun C, Havlir DV, Chamie G, Marquez C, …
• By the Light of Day: Quality, Safety, and Education During the Overnight Admission Handoff.
  Cureus 2019 Devendra GP, Ortiz GM, Haber LA
• Unusual Radiographic Presentation of Pneumocystis Pneumonia in a Patient with AIDS.
  Case reports in infectious diseases 2017 Block BL, Mehta T, Ortiz GM, Ferris SP, Vu TH, Huang L, Cattamanchi A
• Clearing the air: inpatient providers' knowledge, perspectives, and experience with electronic cigarettes.
  Journal of hospital medicine 2014 Haber LA, Ortiz GM
• Levels of circulating myeloid subpopulations and of heme oxygenase-1 do not predict CD4(+) T cell recovery after the initiation of antiretroviral therapy for HIV disease.
  AIDS research and therapy 2014 Seu L, Ortiz GM, Burt TD, Deeks SG, Martin JN, McCune JM
• Higher CD27+CD8+ T cells percentages during suppressive antiretroviral therapy predict greater subsequent CD4+ T cell recovery in treated HIV infection.
  PloS one 2013 Seu L, Ortiz GM, Epling L, Sinclair E, Swainson LA, Bajpai UD, Huang Y, Deeks SG, Hunt PW, Martin JN, McCune JM
• Morphine produces immunosuppressive effects in nonhuman primates at the proteomic and cellular levels.
  Molecular & cellular proteomics : MCP 2012 Brown JN, Ortiz GM, Angel TE, Jacobs JM, Gritsenko M, Chan EY, Purdy DE, Murnane RD, Larsen K, Palermo RE, Shukla AK, Clauss TR, Katze MG, McCune JM, Smith RD
• Detection of T lymphocytes specific for human endogenous retrovirus K (HERV-K) in patients with seminoma.
  AIDS research and human retroviruses 2006 Rakoff-Nahoum S, Kuebler PJ, Heymann JJ, E Sheehy M, Ortiz GM, S Ogg G, Barbour JD, Lenz J, Steinfeld AD, Nixon DF
• Relevance of HIV-1-specific CD4+ helper T-cell responses during structured treatment interruptions in patients with CD4+ T-cell nadir above 400/mm3.
  Journal of acquired immune deficiency syndromes (1999) 2004 Plana M, Garcia F, Oxenius A, Ortiz GM, Lopez A, Cruceta A, Mestre G, Fumero E, Fagard C, Sambeat MA, Segura F, Miró JM, Arnedo M, Lopalcos L, Pumarola T, Hirschel B, Phillips RE, Nixon DF, Gallart T,…
• Changes in CD4+ T-cell differentiation phenotype during structured treatment interruption in patients with chronic HIV-1 infection.
  Journal of acquired immune deficiency syndromes (1999) 2003 Alexander TH, Ortiz GM, Wellons MF, Allen A, Grace EJ, Schweighardt B, Brancato J, Sandberg JK, Furlan SN, Miralles GD, Nixon DF, Bartlett JA
• Dual pressure from antiretroviral therapy and cell-mediated immune response on the human immunodeficiency virus type 1 protease gene.
  Journal of virology 2003 Karlsson AC, Deeks SG, Barbour JD, Heiken BD, Younger SR, Hoh R, Lane M, Sällberg M, Ortiz GM, Demarest JF, Liegler T, Grant RM, Martin JN, Nixon DF
• A cytostatic drug improves control of HIV-1 replication during structured treatment interruptions: a randomized study.
  AIDS (London, England) 2003 García F, Plana M, Arnedo M, Ortiz GM, Miró JM, Lopalco L, Lori F, Pumarola T, Gallart T, Gatell JM
• Emergence of drug-resistant HIV-1 variants in patients undergoing structured treatment interruptions.
  AIDS (London, England) 2002 Schweighardt B, Ortiz GM, Grant RM, Wellons M, Miralles GD, Kostrikis LG, Bartlett JA, Nixon DF
• Residual viral replication during antiretroviral therapy boosts human immunodeficiency virus type 1-specific CD8+ T-cell responses in subjects treated early after infection.
  Journal of virology 2002 Ortiz GM, Hu J, Goldwitz JA, Chandwani R, Larsson M, Bhardwaj N, Bonhoeffer S, Ramratnam B, Zhang L, Markowitz MM, Nixon DF
• Structured antiretroviral treatment interruptions in chronically HIV-1-infected subjects.
  Proceedings of the National Academy of Sciences of the United States of America 2001 Ortiz GM, Wellons M, Brancato J, Vo HT, Zinn RL, Clarkson DE, Van Loon K, Bonhoeffer S, Miralles GD, Montefiori D, Bartlett JA, Nixon DF
• The virological and immunological consequences of structured treatment interruptions in chronic HIV-1 infection.
  AIDS (London, England) 2001 García F, Plana M, Ortiz GM, Bonhoeffer S, Soriano A, Vidal C, Cruceta A, Arnedo M, Gil C, Pantaleo G, Pumarola T, Gallart T, Nixon DF, Miró JM, Gatell JM
• Risks and benefits of structured antiretroviral drug therapy interruptions in HIV-1 infection.
  AIDS (London, England) 2000 Bonhoeffer S, Rembiszewski M, Ortiz GM, Nixon DF
• Enhancement of human immunodeficiency virus type 1-specific CD4 and CD8 T cell responses in chronically infected persons after temporary treatment interruption.
  The Journal of infectious diseases 2000 Papasavvas E, Ortiz GM, Gross R, Sun J, Moore EC, Heymann JJ, Moonis M, Sandberg JK, Drohan LA, Gallagher B, Shull J, Nixon DF, Kostman JR, Montaner LJ
• The relationship between T cell proliferative responses and plasma viremia during treatment of human immunodeficiency virus type 1 infection with combination antiretroviral therapy.
  The Journal of infectious diseases 2000 Binley JM, Schiller DS, Ortiz GM, Hurley A, Nixon DF, Markowitz MM, Moore JP
• HIV-1-specific immune responses in subjects who temporarily contain virus replication after discontinuation of highly active antiretroviral therapy.
  The Journal of clinical investigation 1999 Ortiz GM, Nixon DF, Trkola A, Binley J, Jin X, Bonhoeffer S, Kuebler PJ, Donahoe SM, Demoitie MA, Kakimoto WM, Ketas T, Clas B, Heymann JJ, Zhang L, Cao Y, Hurley A, Moore JP, Ho DD, Markowitz M
• Cell-free transfer of cholesterol from lysosomes to phospholipid vesicles.
  Journal of lipid research 1996 Johnson WJ
• Digitoxin metabolism by rat liver microsomes.
  Biochemical pharmacology 1975 Schmoldt A, Benthe HF, Haberland G
• [Biochemical studies on camomile components/III. In vitro studies about the antipeptic activity of (--)-alpha-bisabolol (author's transl)].
  Arzneimittel-Forschung 1975 Isaac O, Thiemer K
• The ophthalmologist's office: planning and practice. Patient traffic flow and use of paramedical personnel.
  International ophthalmology clinics 1975 Byron HM
• “Acinetobacter in military personnel.” Case vignette as part of www.antimicrobe.org
  “Acinetobacter in military personnel.” Case vignette as part of www.antimicrobe.org Gabriel M. Ortiz and David Graham