Frederick Hecht, MD
Professor
Medicine
School of Medicine

In 2002, I became Director of Research at the UCSF Osher Center for Integrative Medicine. My research is driven by the belief that modern medicine has made impressive advances in treating a range of health conditions, but that further advances for many of the most important health problems of our era, including obesity, diabetes, heart disease, and mental health issues require improved development and implementation of lifestyle and other non-pharmacologic approaches. An important goal of my research program is to rigorously test whether we can improve interventions for chronic health problems such as HIV, diabetes, obesity, and stress, by incorporating mindfulness and/or yoga-based components. A current example is an NIH-funded study to test whether including training in mindful eating practices decreases eating in response to food cravings and enhances adherence to a nutritional plan in type 2 diabetes. I bring a focus on clinical research methodology to the projects I am involved with. I am particularly interested in the use of innovative research methodology to strengthen the rigor of research on nonpharmacolgic health interventions, including factorial trials and Sequential Multiple Assignment Randomized Trials (SMARTs), and assessment of teacher factors in mindfulness programs to improve intervention fidelity .

In my role as Director of the UCSF Osher Center Research Program, I have played a key leadership role in building it into an internationally recognized integrative medicine research center that is distinguished by the application of innovative and rigorous research designs to studying mindfulness-based interventions, yoga, acupuncture, interoceptive awareness, and behavioral interventions. I have served in a variety of leadership roles in HIV medicine and integrative health, including as board chair of the Academic Consortium for Integrative Medicine and Health, which gives me a broad view of the field. I have a strong commitment to mentoring. I have led UCSF’s highly successful Training Research in Integrative Medicine (TRIM) fellowship program since 2006, and have served as a primary or main co-mentor for 12 NIH K awardees. I have served as PI or co-PI/project director for 31 grants, 19 of them from NIH, including leading three Program Project grants.

• A cohort-based study of host gene expression: tumor suppressor and innate immune/inflammatory pathways associated with the HIV reservoir size.
  PLoS pathogens 2023 Dwivedi AK, Gornalusse GG, Siegel DA, Barbehenn A, Thanh C, Hoh R, Hobbs KS, Pan T, Gibson EA, Martin J, Hecht F, Pilcher C, Milush J, Busch MP, Stone M, Huang ML, Reppetti J, Vo PM, Levy CN, …
• Correction: Variability of temperature measurements recorded by a wearable device by biological sex.
  Biology of sex differences 2023 Bruce LK, Kasl P, Soltani S, Viswanath VK, Hartogensis W, Dilchert S, Hecht FM, Chowdhary A, Anglo C, Pandya L, Dasgupta S, Altintas I, Gupta A, Mason AE, Smarr BL
• The more symptoms the better? Covid-19 vaccine side effects and long-term neutralizing antibody response.
  medRxiv : the preprint server for health sciences 2023 Dutcher EG, Epel ES, Mason AE, Hecht FM, Robinson JE, Drury SS, Prather AA
• Variability of temperature measurements recorded by a wearable device by biological sex.
  Biology of sex differences 2023 Bruce LK, Kasl P, Soltani S, Viswanath VK, Hartogensis W, Dilchert S, Hecht FM, Chowdhary A, Anglo C, Pandya L, Dasgupta S, Altintas I, Gupta A, Mason AE, Smarr BL
• Estimating the contribution of CD4 T cell subset proliferation and differentiation to HIV persistence.
  Nature communications 2023 Reeves DB, Bacchus-Souffan C, Fitch M, Abdel-Mohsen M, Hoh R, Ahn H, Stone M, Hecht F, Martin J, Deeks SG, Hellerstein MK, McCune JM, Schiffer JT, Hunt PW
• Protocol for a randomized controlled trial comparing a very low-carbohydrate diet or moderate-carbohydrate plate-method diet for type 2 diabetes: the LEGEND (Lifestyle Education about Nutrition for Diabetes) trial.
  Trials 2023 Saslow LR, Eslamian A, Moran P, Hartogensis W, Mason AE, Kim S, Bauer DC, Griauzde DH, Goldman V, Liu V, Stephens P, Raymond K, Yeung G, Leung C, Hecht FM
• The Reliability of Rating via Audio-Recording Using the Mindfulness-Based Interventions: Teaching Assessment Criteria.
  Global advances in integrative medicine and health 2023 Floyd E, Adler SR, Crane RS, Brewer J, Moran P, Richler R, Hartogensis W, Kuyken W, Hecht FM
• Psychological Support Strategies for Adults With Type 2 Diabetes in a Very Low-Carbohydrate Web-Based Program: Randomized Controlled Trial.
  JMIR diabetes 2023 Saslow LR, Missel AL, O'Brien A, Kim S, Hecht FM, Moskowitz JT, Bayandorian H, Pietrucha M, Raymond K, Richards B, Liestenfeltz B, Mason AE, Daubenmier J, Aikens JE
• Predictors of long-term neutralizing antibody titers following COVID-19 vaccination by three vaccine types: the BOOST study.
  Scientific reports 2023 Prather AA, Dutcher EG, Robinson J, Lin J, Blackburn E, Hecht FM, Mason AE, Fromer E, Merino B, Frazier R, O'Bryan J, Drury S, Epel ES
• Preventing Depression Relapse: A Qualitative Study on the Need for Additional Structured Support Following Mindfulness-Based Cognitive Therapy.
  Global advances in integrative medicine and health 2023 Siwik CJ, Adler SR, Moran PJ, Kuyken W, Segal Z, Felder J, Eisendrath S, Hecht FM
• Unequal distribution of genetically-intact HIV-1 proviruses in cells expressing the immune checkpoint markers PD-1 and/or CTLA-4.
  Frontiers in immunology 2023 Fisher K, Schlub TE, Boyer Z, Rasmussen TA, Rhodes A, Hoh R, Hecht FM, Deeks SG, Lewin SR, Palmer S
• Differences in expression of tumor suppressor, innate immune, inflammasome, and potassium/gap junction channel host genes significantly predict viral reservoir size during treated HIV infection.
  bioRxiv : the preprint server for biology 2023 Dwivedi AK, Siegel DA, Thanh C, Hoh R, Hobbs KS, Pan T, Gibson EA, Martin J, Hecht F, Pilcher C, Milush J, Busch MP, Stone M, Huang ML, Levy CN, Roychoudhury P, Hladik F, Jerome KR, Henrich TJ, Deeks …
• Transcriptomic Signatures of Human Immunodeficiency Virus Post-Treatment Control.
  Journal of virology 2022 Wedrychowski A, Martin HA, Li Y, Telwatte S, Kadiyala GN, Melberg M, Etemad B, Connick E, Jacobson JM, Margolis DM, Skiest D, Volberding P, Hecht F, Deeks S, Wong JK, Li JZ, Yukl SA
• Host variation in type I interferon signaling genes (MX1), C-C chemokine receptor type 5 gene, and major histocompatibility complex class I alleles in treated HIV+ noncontrollers predict viral reservoir size.
  AIDS (London, England) 2022 Siegel DA, Thanh C, Wan E, Hoh R, Hobbs K, Pan T, Gibson EA, Kroetz DL, Martin J, Hecht F, Pilcher C, Martin M, Carrington M, Pillai S, Busch MP, Stone M, Levy CN, Huang ML, Roychoudhury P, Hladik F, …
• Methods for detecting probable COVID-19 cases from large-scale survey data also reveal probable sex differences in symptom profiles.
  Frontiers in big data 2022 Klein A, Puldon K, Dilchert S, Hartogensis W, Chowdhary A, Anglo C, Pandya LS, Hecht FM, Mason AE, Smarr BL
• Effects of a Mindfulness-Based Weight Loss Intervention on Long-Term Psychological Well-Being Among Adults with Obesity: Secondary Analyses from the Supporting Health by Integrating Nutrition and Exercise (SHINE) Trial.
  Mindfulness 2022 Hooker AR, Sagui-Henson SJ, Daubenmier J, Moran PJ, Hartogensis W, Acree M, Kristeller J, Epel ES, Mason AE, Hecht FM
• Cell-Associated Human Immunodeficiency Virus (HIV) Ribonucleic Acid Has a Circadian Cycle in Males With HIV on Antiretroviral Therapy.
  The Journal of infectious diseases 2022 Stern J, Solomon A, Dantanarayana A, Pascoe R, Reynaldi A, Davenport MP, Milush J, Deeks SG, Hartogensis W, Hecht FM, Cockerham L, Roche M, Lewin SR
• Cellular Activation, Differentiation, and Proliferation Influence the Dynamics of Genetically Intact Proviruses Over Time.
  The Journal of infectious diseases 2022 Horsburgh BA, Hiener B, Fisher K, Lee E, Morgan H, Eden JS, von Stockenstrom S, Odevall L, Milush JM, Hoh R, Fromentin R, Chomont N, Hecht FM, Schlub TE, Deeks SG, Palmer S
• Examining Experiences of Poor Sleep During Pregnancy: A Qualitative Study to Inform the Development of a Prenatal Sleep Intervention.
  Global advances in health and medicine 2022 Felder JN, Mirchandaney R, Harrison J, Manber R, Cuneo J, Krystal A, Epel E, Hecht F
• Author Correction: Detection of COVID-19 using multimodal data from a wearable device: results from the first TemPredict Study.
  Scientific reports 2022 Mason AE, Hecht FM, Davis SK, Natale JL, Hartogensis W, Damaso N, Claypool KT, Dilchert S, Dasgupta S, Purawat S, Viswanath VK, Klein A, Chowdhary A, Fisher SM, Anglo C, Puldon KY, Veasna D, Prather …
• Author Correction: Feasibility of continuous fever monitoring using wearable devices.
  Scientific reports 2022 Smarr BL, Aschbacher K, Fisher SM, Chowdhary A, Dilchert S, Puldon K, Rao A, Hecht FM, Mason AE
• Detection of COVID-19 using multimodal data from a wearable device: results from the first TemPredict Study.
  Scientific reports 2022 Mason AE, Hecht FM, Davis SK, Natale JL, Hartogensis W, Damaso N, Claypool KT, Dilchert S, Dasgupta S, Purawat S, Viswanath VK, Klein A, Chowdhary A, Fisher SM, Anglo C, Puldon KY, Veasna D, Prather …
• Metrics from Wearable Devices as Candidate Predictors of Antibody Response Following Vaccination against COVID-19: Data from the Second TemPredict Study.
  Vaccines 2022 Mason AE, Kasl P, Hartogensis W, Natale JL, Dilchert S, Dasgupta S, Purawat S, Chowdhary A, Anglo C, Veasna D, Pandya LS, Fox LM, Puldon KY, Prather JG, Gupta A, Altintas I, Smarr BL, Hecht FM
• Feasibility and Acceptability of a Physical Activity Tracker and Text Messages to Promote Physical Activity During Chemotherapy for Colorectal Cancer: Pilot Randomized Controlled Trial (Smart Pace II).
  JMIR cancer 2022 Van Blarigan EL, Dhruva A, Atreya CE, Kenfield SA, Chan JM, Milloy A, Kim I, Steiding P, Laffan A, Zhang L, Piawah S, Fukuoka Y, Miaskowski C, Hecht FM, Kim MO, Venook AP, Van Loon K
• Being Present 2.0: Online Mindfulness-Based Program for Metastatic Gastrointestinal Cancer Patients and Caregivers.
  Global advances in health and medicine 2021 Dragomanovich HM, Dhruva A, Ekman E, Schoenbeck KL, Kubo A, Van Blarigan EL, Borno HT, Esquivel M, Chee B, Campanella M, Philip EJ, Rettger JP, Rosenthal B, Van Loon K, Venook AP, Boscardin C, Moran P…
• Frequency of post treatment control varies by antiretroviral therapy restart and viral load criteria.
  AIDS (London, England) 2021 Fajnzylber J, Sharaf R, Hutchinson JN, Aga E, Bosch RJ, Hartogensis W, Jacobson JM, Connick E, Volberding P, Skiest DJ, Margolis D, Sneller MC, Little SJ, Gulick RM, Mellors JW, Gandhi RT, Schooley RT…
• Methods-Motivational Interviewing Approach for Enhanced Retention and Attendance.
  American journal of preventive medicine 2021 Jake-Schoffman DE, Brown SD, Baiocchi M, Bibeau JL, Daubenmier J, Ferrara A, Galarce MN, Hartogensis W, Hecht FM, Hedderson MM, Moran PJ, Pagoto SL, Tsai AL, Waring ME, Kiernan M
• Alternative Dietary Patterns for Americans: Low-Carbohydrate Diets.
  Nutrients 2021 Volek JS, Phinney SD, Krauss RM, Johnson RJ, Saslow LR, Gower B, Yancy WS, King JC, Hecht FM, Teicholz N, Bistrian BR, Hamdy O
• HIV-1 Genomes Are Enriched in Memory CD4+ T-Cells with Short Half-Lives.
  mBio 2021 Morcilla V, Bacchus-Souffan C, Fisher K, Horsburgh BA, Hiener B, Wang XQ, Schlub TE, Fitch M, Hoh R, Hecht FM, Martin JN, Deeks SG, Hellerstein MK, McCune JM, Hunt PW, Palmer S
• Exploratory Analysis of Racial/Ethnic and Educational Differences in a Randomized Controlled Trial of a Mindfulness-Based Weight Loss Intervention.
  Psychosomatic medicine 2021 Daubenmier J, Chao MT, Hartogensis W, Liu R, Moran PJ, Acree MC, Kristeller J, Epel ES, Hecht FM
• Abnormal Levels of Some Biomarkers of Immune Activation Despite Very Early Treatment of Human Immunodeficiency Virus.
  The Journal of infectious diseases 2021 Schnittman SR, Deitchman AN, Beck-Engeser G, Ahn H, York VA, Hartig H, Hecht FM, Martin JN, Deeks SG, Aweeka FT, Hunt PW
• Complex wavelet filter improves FLIM phasors for photon starved imaging experiments.
  Biomedical optics express 2021 Wang P, Hecht F, Ossato G, Tille S, Fraser SE, Junge JA
• Enhanced Stress Resilience Training in Surgeons: Iterative Adaptation and Biopsychosocial Effects in 2 Small Randomized Trials.
  Annals of surgery 2021 Lebares CC, Coaston TN, Delucchi KL, Guvva EV, Shen WT, Staffaroni AM, Kramer JH, Epel ES, Hecht FM, Ascher NL, Harris HW, Cole SW
• TCF-1 regulates HIV-specific CD8+ T cell expansion capacity.
  JCI insight 2021 Rutishauser RL, Deguit CDT, Hiatt J, Blaeschke F, Roth TL, Wang L, Raymond KA, Starke CE, Mudd JC, Chen W, Smullin C, Matus-Nicodemos R, Hoh R, Krone M, Hecht FM, Pilcher CD, Martin JN, Koup RA, Douek…
• Relationship between CD4 T cell turnover, cellular differentiation and HIV persistence during ART.
  PLoS pathogens 2021 Bacchus-Souffan C, Fitch M, Symons J, Abdel-Mohsen M, Reeves DB, Hoh R, Stone M, Hiatt J, Kim P, Chopra A, Ahn H, York VA, Cameron DL, Hecht FM, Martin JN, Yukl SA, Mallal S, Cameron PU, Deeks SG, …
• Corrigendum: Toward a Compassionate Intersectional Neuroscience: Increasing Diversity and Equity in Contemplative Neuroscience.
  Frontiers in psychology 2021 Weng HY, Ikeda MP, Lewis-Peacock JA, Chao MT, Fullwiley D, Goldman V, Skinner S, Duncan LG, Gazzaley A, Hecht FM
• Feasibility of continuous fever monitoring using wearable devices.
  Scientific reports 2020 Smarr BL, Aschbacher K, Fisher SM, Chowdhary A, Dilchert S, Puldon K, Rao A, Hecht FM, Mason AE
• A 4-Month Whole-Systems Ayurvedic Medicine Nutrition and Lifestyle Intervention Is Feasible and Acceptable for Breast Cancer Survivors: Results of a Single-Arm Pilot Clinical Trial.
  Global advances in health and medicine 2020 Dhruva A, Wu C, Miaskowski C, Hartogensis W, Rugo HS, Adler SR, Kaptchuk TJ, Kelkar R, Agarawal S, Vadodaria A, Garris E, Hecht FM
• Toward a Compassionate Intersectional Neuroscience: Increasing Diversity and Equity in Contemplative Neuroscience.
  Frontiers in psychology 2020 Weng HY, Ikeda MP, Lewis-Peacock JA, Chao MT, Fullwiley D, Goldman V, Skinner S, Duncan LG, Gazzaley A, Hecht FM
• Can We Agree What Skilled Mindfulness-Based Teaching Looks Like? Lessons From Studying the MBI:TAC.
  Global advances in health and medicine 2020 S Crane R, Hecht FM, Brewer J, Griffith GM, Hartogensis W, Koerbel L, Moran P, Sansom S, Yiangou A, Kuyken W
• Pilot Cluster Randomized Controlled Trial of Integrative Nutritional Counseling Versus Standard Diabetes Self-Management Education for Chinese Americans with Type 2 Diabetes.
  Health equity 2020 Ho EY, Pak S, Leung G, Xu S, Yu CK, Hecht FM, Jih J, Chao MT
• Intervention Enhancement Strategies Among Adults With Type 2 Diabetes in a Very Low-Carbohydrate Web-Based Program: Evaluating the Impact With a Randomized Trial.
  JMIR diabetes 2020 Saslow LR, Moskowitz JT, Mason AE, Daubenmier J, Liestenfeltz B, Missel AL, Bayandorian H, Aikens JE, Kim S, Hecht FM
• Focus on the Breath: Brain Decoding Reveals Internal States of Attention During Meditation.
  Frontiers in human neuroscience 2020 Weng HY, Lewis-Peacock JA, Hecht FM, Uncapher MR, Ziegler DA, Farb NAS, Goldman V, Skinner S, Duncan LG, Chao MT, Gazzaley A
• Delayed Expression of PD-1 and TIGIT on HIV-Specific CD8 T Cells in Untreated HLA-B*57:01 Individuals Followed from Early Infection.
  Journal of virology 2020 Scharf L, Tauriainen J, Buggert M, Hartogensis W, Nolan DJ, Deeks SG, Salemi M, Hecht FM, Karlsson AC
• Longitudinal study reveals HIV-1-infected CD4+ T cell dynamics during long-term antiretroviral therapy.
  The Journal of clinical investigation 2020 Antar AA, Jenike KM, Jang S, Rigau DN, Reeves DB, Hoh R, Krone MR, Keruly JC, Moore RD, Schiffer JT, Nonyane BA, Hecht FM, Deeks SG, Siliciano JD, Ho YC, Siliciano RF
• "It Gave Me Hope" Experiences of Diverse Safety Net Patients in a Group Acupuncture Intervention for Painful Diabetic Neuropathy.
  Health equity 2020 Liu R, Santana T, Schillinger D, Hecht FM, Chao MT
• Semen virome of men with HIV on or off antiretroviral treatment.
  AIDS (London, England) 2020 Li Y, Altan E, Pilcher C, Hartogensis W, Hecht FM, Deng X, Delwart E
• High levels of genetically intact HIV in HLA-DR+ memory T cells indicates their value for reservoir studies.
  AIDS (London, England) 2020 Horsburgh BA, Lee E, Hiener B, Eden JS, Schlub TE, von Stockenstrom S, Odevall L, Milush JM, Liegler T, Sinclair E, Hoh R, Boritz EA, Douek DC, Fromentin R, Chomont N, Deeks SG, Hecht FM, Palmer S
• Human Immunodeficiency Virus (HIV)-Infected CCR6+ Rectal CD4+ T Cells and HIV Persistence On Antiretroviral Therapy.
  The Journal of infectious diseases 2020 Anderson JL, Khoury G, Fromentin R, Solomon A, Chomont N, Sinclair E, Milush JM, Hartogensis W, Bacchetti P, Roche M, Tumpach C, Gartner M, Pitman MC, Epling CL, Hoh R, Hecht FM, Somsouk M, Cameron PU…
• Impact of Antiretroviral Therapy Duration on HIV-1 Infection of T Cells within Anatomic Sites.
  Journal of virology 2020 Lee E, von Stockenstrom S, Morcilla V, Odevall L, Hiener B, Shao W, Hartogensis W, Bacchetti P, Milush J, Liegler T, Sinclair E, Hatano H, Hoh R, Somsouk M, Hunt P, Boritz E, Douek D, Fromentin R, …
• Correction: Examining the Effects of Mindful Eating Training on Adherence to a Carbohydrate-Restricted Diet in Patients With Type 2 Diabetes (the DELISH Study): Protocol for a Randomized Controlled Trial.
  JMIR research protocols 2020 Mason AE, Saslow L, Moran PJ, Kim S, Wali PK, Abousleiman H, Hartman A, Richler R, Schleicher S, Hartogensis W, Epel ES, Hecht F
• Correction to: Lipid findings from the Diabetes Education to Lower Insulin, Sugars, and Hunger (DELISH) Study.
  Nutrition & metabolism 2019 Mason AE, Saslow LR, Moran PJ, Kim S, Wali PK, Abousleiman H, Richler R, Schleicher S, Goldman VM, Hartman A, Leung C, Hartogensis W, Hecht FM
• Ketogenic Diets for Diabetes and Obesity.
  JAMA internal medicine 2019 Hecht FM
• Do stress eating or compulsive eating influence metabolic health in a mindfulness-based weight loss intervention?
  Health psychology : official journal of the Division of Health Psychology, American Psychological Association 2019 Radin RM, Epel ES, Daubenmier J, Moran P, Schleicher S, Kristeller J, Hecht FM, Mason AE
• A Randomized Clinical Trial of Group Acupuncture for Painful Diabetic Neuropathy Among Diverse Safety Net Patients.
  Pain medicine (Malden, Mass.) 2019 Chao MT, Schillinger D, Nguyen U, Santana T, Liu R, Gregorich S, Hecht FM
• Effects of a Mindfulness-Based Intervention on Distress, Weight Gain, and Glucose Control for Pregnant Low-Income Women: A Quasi-Experimental Trial Using the ORBIT Model.
  International journal of behavioral medicine 2019 Epel E, Laraia B, Coleman-Phox K, Leung C, Vieten C, Mellin L, Kristeller JL, Thomas M, Stotland N, Bush N, Lustig RH, Dallman M, Hecht FM, Adler N
• Acupressure and Therapeutic Touch in Childhood Cancer to Promote Subjective and Intersubjective Experiences of Well-being During Curative Treatment.
  Global advances in health and medicine 2019 Hu H, Shear D, Thakkar R, Thompson-Lastad A, Pinderhughes H, Hecht FM, Lown EA
• Memory CD4 + T-Cells Expressing HLA-DR Contribute to HIV Persistence During Prolonged Antiretroviral Therapy.
  Frontiers in microbiology 2019 Lee E, Bacchetti P, Milush J, Shao W, Boritz E, Douek D, Fromentin R, Liegler T, Hoh R, Deeks SG, Hecht FM, Chomont N, Palmer S
• A Randomized Controlled Trial of a Mindfulness-Based Weight Loss Intervention on Cardiovascular Reactivity to Social-Evaluative Threat Among Adults with Obesity.
  Mindfulness 2019 Daubenmier J, Epel ES, Moran PJ, Thompson J, Mason AE, Acree M, Goldman V, Kristeller J, Hecht FM, Mendes WB
• Lipid findings from the Diabetes Education to Lower Insulin, Sugars, and Hunger (DELISH) Study.
  Nutrition & metabolism 2019 Mason AE, Saslow LR, Moran PJ, Kim S, Abousleiman H, Richler R, Schleicher S, Goldman VM, Hartman A, Leung C, Hartogensis W, Hecht FM
• Acupressure to Reduce Treatment-Related Symptoms for Children With Cancer and Recipients of Hematopoietic Stem Cell Transplant: Protocol for a Randomized Controlled Trial.
  Global advances in health and medicine 2019 Lown EA, Banerjee A, Vittinghoff E, Dvorak CC, Hartogensis W, Melton A, Mangurian C, Hu H, Shear D, Adcock R, Morgan M, Golden C, Hecht FM
• Academic Consortium for Integrative Medicine & Health Commentary to CMS; RE: National Coverage Analysis (NCA) Tracking Sheet for Acupuncture for Chronic Low Back Pain (CAG-00452N).
  Global advances in health and medicine 2019 Nielsen A, Tick H, Mao JJ, Hecht F, Consortium Pain Task Force
• Examining the Effects of Mindful Eating Training on Adherence to a Carbohydrate-Restricted Diet in Patients With Type 2 Diabetes (the DELISH Study): Protocol for a Randomized Controlled Trial.
  JMIR research protocols 2019 Mason AE, Saslow L, Moran PJ, Kim S, Wali PK, Abousleiman H, Hartman A, Richler R, Schleicher S, Hartogensis W, Epel ES, Hecht F
• PD-1 blockade potentiates HIV latency reversal ex vivo in CD4+ T cells from ART-suppressed individuals.
  Nature communications 2019 Fromentin R, DaFonseca S, Costiniuk CT, El-Far M, Procopio FA, Hecht FM, Hoh R, Deeks SG, Hazuda DJ, Lewin SR, Routy JP, Sékaly RP, Chomont N
• The Control of HIV After Antiretroviral Medication Pause (CHAMP) Study: Posttreatment Controllers Identified From 14 Clinical Studies.
  The Journal of infectious diseases 2018 Namazi G, Fajnzylber JM, Aga E, Bosch RJ, Acosta EP, Sharaf R, Hartogensis W, Jacobson JM, Connick E, Volberding P, Skiest D, Margolis D, Sneller MC, Little SJ, Gianella S, Smith DM, Kuritzkes DR, …
• Variation in cell-associated unspliced HIV RNA on antiretroviral therapy is associated with the circadian regulator brain-and-muscle-ARNT-like-1.
  AIDS (London, England) 2018 Chang CC, Naranbhai V, Stern J, Roche M, Dantanarayana A, Ke R, Tennakoon S, Solomon A, Hoh R, Hartogensis W, Hecht FM, Sikaris K, Price DJ, Elliott JH, Deeks SG, Churchill M, Cameron PU, Hengartner N…
• Burnout and gender in surgical training: A call to re-evaluate coping and dysfunction.
  American journal of surgery 2018 Lebares CC, Braun HJ, Guvva EV, Epel ES, Hecht FM
• Weight Loss Maintenance and Cellular Aging in the Supporting Health Through Nutrition and Exercise Study.
  Psychosomatic medicine 2018 Mason AE, Hecht FM, Daubenmier JJ, Sbarra DA, Lin J, Moran PJ, Schleicher SG, Acree M, Prather AA, Epel ES
• A randomized, controlled trial of mindfulness-based stress reduction in HIV infection.
  Brain, behavior, and immunity 2018 Hecht FM, Moskowitz JT, Moran P, Epel ES, Bacchetti P, Acree M, Kemeny ME, Mendes WB, Duncan LG, Weng H, Levy JA, Deeks SG, Folkman S
• Increasing Physical Activity in Mothers Using Video Exercise Groups and Exercise Mobile Apps: Randomized Controlled Trial.
  Journal of medical Internet research 2018 Mascarenhas MN, Chan JM, Vittinghoff E, Van Blarigan EL, Hecht F
• Authors' Reply: Comment on "An Online Intervention Comparing a Very Low-Carbohydrate Ketogenic Diet and Lifestyle Recommendations Versus a Plate Method Diet in Overweight Individuals With Type 2 Diabetes: A Randomized Controlled Trial".
  Journal of medical Internet research 2018 Saslow L, Mason AE, Kim S, Goldman V, Ploutz-Snyder R, Bayandorian H, Daubenmier J, Hecht FM, Moskowitz JT
• Novel Interventions to Reduce Stress and Overeating in Overweight Pregnant Women: A Feasibility Study.
  Maternal and child health journal 2018 Laraia BA, Adler NE, Coleman-Phox K, Vieten C, Mellin L, Kristeller JL, Thomas M, Stotland NE, Lustig RH, Dallman MF, Hecht FM, Bush NR, de Groat CL, Epel E
• Positive and Negative Self-Conscious Emotion and Transmission Risk Following HIV Diagnosis.
  AIDS and behavior 2018 Batchelder AW, Carrico AW, Acree M, Hecht FM, Moskowitz JT
• Intervention Integrity in Mindfulness-Based Research.
  Mindfulness 2018 Crane RS, Hecht FM
• Differential Expression of CD8+ T Cell Cytotoxic Effector Molecules in Blood and Gastrointestinal Mucosa in HIV-1 Infection.
  Journal of immunology (Baltimore, Md. : 1950) 2018 Kiniry BE, Hunt PW, Hecht FM, Somsouk M, Deeks SG, Shacklett BL
• Twelve-month outcomes of a randomized trial of a moderate-carbohydrate versus very low-carbohydrate diet in overweight adults with type 2 diabetes mellitus or prediabetes.
  Nutrition & diabetes 2017 Saslow LR, Daubenmier JJ, Moskowitz JT, Kim S, Murphy EJ, Phinney SD, Ploutz-Snyder R, Goldman V, Cox RM, Mason AE, Moran P, Hecht FM
• Identification of Genetically Intact HIV-1 Proviruses in Specific CD4+ T Cells from Effectively Treated Participants.
  Cell reports 2017 Hiener B, Horsburgh BA, Eden JS, Barton K, Schlub TE, Lee E, von Stockenstrom S, Odevall L, Milush JM, Liegler T, Sinclair E, Hoh R, Boritz EA, Douek D, Fromentin R, Chomont N, Deeks SG, Hecht FM, …
• Anti-HERV-K (HML-2) capsid antibody responses in HIV elite controllers.
  Retrovirology 2017 de Mulder M, SenGupta D, Deeks SG, Martin JN, Pilcher CD, Hecht FM, Sacha JB, Nixon DF, Michaud HA
• Enriched environment and stress exposure influence splenic B lymphocyte composition.
  PloS one 2017 Gurfein BT, Hasdemir B, Milush JM, Touma C, Palme R, Nixon DF, Darcel N, Hecht FM, Bhargava A
• HIV Antibody Level as a Marker of HIV Persistence and Low-Level Viral Replication.
  The Journal of infectious diseases 2017 Keating SM, Pilcher CD, Jain V, Lebedeva M, Hampton D, Abdel-Mohsen M, Deng X, Murphy G, Welte A, Facente SN, Hecht F, Deeks SG, Pillai SK, Busch MP
• Improving Assessment of the Spectrum of Reward-Related Eating: The RED-13.
  Frontiers in psychology 2017 Mason AE, Vainik U, Acree M, Tomiyama AJ, Dagher A, Epel ES, Hecht FM
• Early and Delayed Antiretroviral Therapy Results in Comparable Reductions in CD8+ T Cell Exhaustion Marker Expression.
  AIDS research and human retroviruses 2017 Rutishauser RL, Hartogensis W, Deguit CD, Krone M, Hoh R, Hecht FM, Pilcher CD, Bacchetti P, Deeks SG, Hunt PW, McCune JM
• A humanized mouse-based HIV-1 viral outgrowth assay with higher sensitivity than in vitro qVOA in detecting latently infected cells from individuals on ART with undetectable viral loads.
  Virology 2017 Charlins P, Schmitt K, Remling-Mulder L, Hogan LE, Hanhauser E, Hobbs KS, Hecht F, Deeks SG, Henrich TJ, Akkina R
• Human Immunodeficiency Virus Persistence and T-Cell Activation in Blood, Rectal, and Lymph Node Tissue in Human Immunodeficiency Virus-Infected Individuals Receiving Suppressive Antiretroviral Therapy.
  The Journal of infectious diseases 2017 Khoury G, Fromentin R, Solomon A, Hartogensis W, Killian M, Hoh R, Somsouk M, Hunt PW, Girling V, Sinclair E, Bacchetti P, Anderson JL, Hecht FM, Deeks SG, Cameron PU, Chomont N, Lewin SR
• An Online Intervention Comparing a Very Low-Carbohydrate Ketogenic Diet and Lifestyle Recommendations Versus a Plate Method Diet in Overweight Individuals With Type 2 Diabetes: A Randomized Controlled Trial.
  Journal of medical Internet research 2017 Saslow LR, Mason AE, Kim S, Goldman V, Ploutz-Snyder R, Bayandorian H, Daubenmier J, Hecht FM, Moskowitz JT
• Comprehensive and Medically Appropriate Food Support Is Associated with Improved HIV and Diabetes Health.
  Journal of urban health : bulletin of the New York Academy of Medicine 2017 Palar K, Napoles T, Hufstedler LL, Seligman H, Hecht FM, Madsen K, Ryle M, Pitchford S, Frongillo EA, Weiser SD
• Feasibility and Preliminary Efficacy of a Novel RDoC-Based Treatment Program for Adolescent Depression: "Training for Awareness Resilience and Action" (TARA)-A Pilot Study.
  Frontiers in psychiatry 2017 Henje Blom E, Tymofiyeva O, Chesney MA, Ho TC, Moran P, Connolly CG, Duncan LG, Baldini L, Weng HY, Acree M, Goldman V, Hecht FM, Yang TT
• Perturbed CD8+ T cell TIGIT/CD226/PVR axis despite early initiation of antiretroviral treatment in HIV infected individuals.
  Scientific reports 2017 Tauriainen J, Scharf L, Frederiksen J, Naji A, Ljunggren HG, Sönnerborg A, Lund O, Reyes-Terán G, Hecht FM, Deeks SG, Betts MR, Buggert M, Karlsson AC
• Impact of a Mindfulness-Based Weight-Loss Intervention on Sleep Quality Among Adults with Obesity: Data from the SHINE Randomized Controlled Trial.
  Journal of alternative and complementary medicine (New York, N.Y.) 2016 Adler E, Dhruva A, Moran PJ, Daubenmier J, Acree M, Epel ES, Bacchetti P, Prather AA, Mason A, Hecht FM
• Monitoring Integration over Time Supports a Role for Cytotoxic T Lymphocytes and Ongoing Replication as Determinants of Reservoir Size.
  Journal of virology 2016 Pinzone MR, Graf E, Lynch L, McLaughlin B, Hecht FM, Connors M, Migueles SA, Hwang WT, Nunnari G, O'Doherty U
• Predominance of weakly cytotoxic, T-betLowEomesNeg CD8+ T-cells in human gastrointestinal mucosa: implications for HIV infection.
  Mucosal immunology 2016 Kiniry BE, Ganesh A, Critchfield JW, Hunt PW, Hecht FM, Somsouk M, Deeks SG, Shacklett BL
• Psoriasis risk SNPs and their association with HIV-1 control.
  Human immunology 2016 Nititham J, Gupta R, Zeng X, Hartogensis W, Nixon DF, Deeks SG, Hecht FM, Liao W
• Viral load criteria and threshold optimization to improve HIV incidence assay characteristics.
  AIDS (London, England) 2016 Kassanjee R, Pilcher CD, Busch MP, Murphy G, Facente SN, Keating SM, Mckinney E, Marson K, Price MA, Martin JN, Little SJ, Hecht FM, Kallas EG, Welte A, Consortium for the Evaluation and Performance …
• Correction: Rapid Progressing Allele HLA-B35 Px Restricted Anti-HIV-1 CD8+ T Cells Recognize Vestigial CTL Epitopes.
  PloS one 2016 Willberg CB, Garrison KE, Jones RB, Meiklejohn DA, Spotts G, Liegler TJ, Ostrowski MA, Karlsson AC, Hecht FM, Nixon DF
• CD4+ T Cells Expressing PD-1, TIGIT and LAG-3 Contribute to HIV Persistence during ART.
  PLoS pathogens 2016 Fromentin R, Bakeman W, Lawani MB, Khoury G, Hartogensis W, DaFonseca S, Killian M, Epling L, Hoh R, Sinclair E, Hecht FM, Bacchetti P, Deeks SG, Lewin SR, Sékaly RP, Chomont N
• Immunologic profiles distinguish aviremic HIV-infected adults.
  AIDS (London, England) 2016 Ramirez CM, Sinclair E, Epling L, Lee SA, Jain V, Hsue PY, Hatano H, Conn D, Hecht FM, Martin JN, McCune JM, Deeks SG, Hunt PW
• Persistence of integrated HIV DNA in CXCR3 + CCR6 + memory CD4+ T cells in HIV-infected individuals on antiretroviral therapy.
  AIDS (London, England) 2016 Khoury G, Anderson JL, Fromentin R, Hartogenesis W, Smith MZ, Bacchetti P, Hecht FM, Chomont N, Cameron PU, Deeks SG, Lewin SR
• Adjunctive acupuncture for pain and symptom management in the inpatient setting: protocol for a pilot hybrid effectiveness-implementation study.
  Journal of integrative medicine 2016 Chao MT, Chang A, Reddy S, Harrison JD, Acquah J, Toveg M, Santana T, Hecht FM
• Effects of a mindfulness-based weight loss intervention in adults with obesity: A randomized clinical trial.
  Obesity (Silver Spring, Md.) 2016 Daubenmier J, Moran PJ, Kristeller J, Acree M, Bacchetti P, Kemeny ME, Dallman M, Lustig RH, Grunfeld C, Nixon DF, Milush JM, Goldman V, Laraia B, Laugero KD, Woodhouse L, Epel ES, Hecht FM
• Reduced reward-driven eating accounts for the impact of a mindfulness-based diet and exercise intervention on weight loss: Data from the SHINE randomized controlled trial.
  Appetite 2016 Mason AE, Epel ES, Aschbacher K, Lustig RH, Acree M, Kristeller J, Cohn M, Dallman M, Moran PJ, Bacchetti P, Laraia B, Hecht FM, Daubenmier J
• Factors related to telomere length.
  Brain, behavior, and immunity 2016 Prather AA, Hecht FM, Epel ES
• TIGIT Marks Exhausted T Cells, Correlates with Disease Progression, and Serves as a Target for Immune Restoration in HIV and SIV Infection.
  PLoS pathogens 2016 Chew GM, Fujita T, Webb GM, Burwitz BJ, Wu HL, Reed JS, Hammond KB, Clayton KL, Ishii N, Abdel-Mohsen M, Liegler T, Mitchell BI, Hecht FM, Ostrowski M, Shikuma CM, Hansen SG, Maurer M, Korman AJ, …
• Nausea is associated with endotoxemia during a 161-km ultramarathon.
  Journal of sports sciences 2015 Stuempfle KJ, Valentino T, Hew-Butler T, Hecht FM, Hoffman MD
• Effects of a mindfulness-based intervention on mindful eating, sweets consumption, and fasting glucose levels in obese adults: data from the SHINE randomized controlled trial.
  Journal of behavioral medicine 2015 Mason AE, Epel ES, Kristeller J, Moran PJ, Dallman M, Lustig RH, Acree M, Bacchetti P, Laraia BA, Hecht FM, Daubenmier J
• Efficient Identification of HIV Serodiscordant Couples by Existing HIV Testing Programs in South Brazil.
  PloS one 2015 Pilcher CD, Bisol CA, Paganella MP, Vallabhaneni S, da Motta LR, Kato SK, Sperhacke RD, Kallas EG, Hecht FM, Diaz RS
• Gut-Resident Lactobacillus Abundance Associates with IDO1 Inhibition and Th17 Dynamics in SIV-Infected Macaques.
  Cell reports 2015 Vujkovic-Cvijin I, Swainson LA, Chu SN, Ortiz AM, Santee CA, Petriello A, Dunham RM, Fadrosh DW, Lin DL, Faruqi AA, Huang Y, Apetrei C, Pandrea I, Hecht FM, Pilcher CD, Klatt NR, Brenchley JM, Lynch …
• Experiences with food insecurity and risky sex among low-income people living with HIV/AIDS in a resource-rich setting.
  Journal of the International AIDS Society 2015 Whittle HJ, Palar K, Napoles T, Hufstedler LL, Ching I, Hecht FM, Frongillo EA, Weiser SD
• Dispositional Mindfulness in People with HIV: Associations with Psychological and Physical Health.
  Personality and individual differences 2015 Moskowitz JT, Duncan LG, Moran PJ, Acree M, Epel ES, Kemeny ME, Hecht FM, Folkman S
• Improving Patient-Centered Care: A Cross-Sectional Survey of Prior Use and Interest in Complementary and Integrative Health Approaches Among Hospitalized Oncology Patients.
  Journal of alternative and complementary medicine (New York, N.Y.) 2015 Liu R, Chang A, Reddy S, Hecht FM, Chao MT
• Training in ChiRunning to reduce blood pressure: a randomized controlled pilot study.
  BMC complementary and alternative medicine 2015 McDermott K, Kumar D, Goldman V, Feng H, Mehling W, Moskowitz JT, Souza RB, Hecht FM
• Epigenetic mechanisms, T-cell activation, and CCR5 genetics interact to regulate T-cell expression of CCR5, the major HIV-1 coreceptor.
  Proceedings of the National Academy of Sciences of the United States of America 2015 Gornalusse GG, Mummidi S, Gaitan AA, Jimenez F, Ramsuran V, Picton A, Rogers K, Manoharan MS, Avadhanam N, Murthy KK, Martinez H, Molano Murillo A, Chykarenko ZA, Hutt R, Daskalakis D, Shostakovich-…
• Putting the brakes on the "drive to eat": Pilot effects of naltrexone and reward-based eating on food cravings among obese women.
  Eating behaviors 2015 Mason AE, Laraia B, Daubenmier J, Hecht FM, Lustig RH, Puterman E, Adler N, Dallman M, Kiernan M, Gearhardt AN, Epel ES
• A Novel Assay to Measure the Magnitude of the Inducible Viral Reservoir in HIV-infected Individuals.
  EBioMedicine 2015 Procopio FA, Fromentin R, Kulpa DA, Brehm JH, Bebin AG, Strain MC, Richman DD, O'Doherty U, Palmer S, Hecht FM, Hoh R, Barnard RJ, Miller MD, Hazuda DJ, Deeks SG, Sékaly RP, Chomont N
• Newly Exerted T Cell Pressures on Mutated Epitopes following Transmission Help Maintain Consensus HIV-1 Sequences.
  PloS one 2015 Eriksson EM, Liegler T, Keh CE, Karlsson AC, Holditch SJ, Pilcher CD, Loeb L, Nixon DF, Hecht FM
• Acute responses to opioidergic blockade as a biomarker of hedonic eating among obese women enrolled in a mindfulness-based weight loss intervention trial.
  Appetite 2015 Mason AE, Lustig RH, Brown RR, Acree M, Bacchetti P, Moran PJ, Dallman M, Laraia B, Adler N, Hecht FM, Daubenmier J, Epel ES
• Clinical decision rule for primary care patient with acute low back pain at risk of developing chronic pain.
  The spine journal : official journal of the North American Spine Society 2015 Mehling WE, Ebell MH, Avins AL, Hecht FM
• Can a back pain screening tool help classify patients with acute pain into risk levels for chronic pain?
  European journal of pain (London, England) 2015 Mehling WE, Avins AL, Acree MC, Carey TS, Hecht FM
• Longitudinal Genetic Characterization Reveals That Cell Proliferation Maintains a Persistent HIV Type 1 DNA Pool During Effective HIV Therapy.
  The Journal of infectious diseases 2015 von Stockenstrom S, Odevall L, Lee E, Sinclair E, Bacchetti P, Killian M, Epling L, Shao W, Hoh R, Ho T, Faria NR, Lemey P, Albert J, Hunt P, Loeb L, Pilcher C, Poole L, Hatano H, Somsouk M, Douek D, …
• Select host restriction factors are associated with HIV persistence during antiretroviral therapy.
  AIDS (London, England) 2015 Abdel-Mohsen M, Wang C, Strain MC, Lada SM, Deng X, Cockerham LR, Pilcher CD, Hecht FM, Liegler T, Richman DD, Deeks SG, Pillai SK
• Effects of Form-Focused Training on Running Biomechanics: A Pilot Randomized Trial in Untrained Individuals.
  PM & R : the journal of injury, function, and rehabilitation 2015 Kumar D, McDermott K, Feng H, Goldman V, Luke A, Souza RB, Hecht FM
• Deep sequencing of HIV-1 variants from paired plasma and cerebrospinal fluid during primary HIV infection.
  Journal of virus eradication 2015 Gega A, Kozal MJ, Chiarella J, Lee E, Peterson J, Hecht FM, Liegler T, St John EP, Simen BB, Price RW, Spudich SS
• High Transmissibility During Early HIV Infection Among Men Who Have Sex With Men-San Francisco, California.
  The Journal of infectious diseases 2014 Hollingsworth TD, Pilcher CD, Hecht FM, Deeks SG, Fraser C
• Tired telomeres: Poor global sleep quality, perceived stress, and telomere length in immune cell subsets in obese men and women.
  Brain, behavior, and immunity 2014 Prather AA, Gurfein B, Moran P, Daubenmier J, Acree M, Bacchetti P, Sinclair E, Lin J, Blackburn E, Hecht FM, Epel ES
• CD4+ and CD8+ T cell activation are associated with HIV DNA in resting CD4+ T cells.
  PloS one 2014 Cockerham LR, Siliciano JD, Sinclair E, O'Doherty U, Palmer S, Yukl SA, Strain MC, Chomont N, Hecht FM, Siliciano RF, Richman DD, Deeks SG
• Independent assessment of candidate HIV incidence assays on specimens in the CEPHIA repository.
  AIDS (London, England) 2014 Kassanjee R, Pilcher CD, Keating SM, Facente SN, McKinney E, Price MA, Martin JN, Little S, Hecht FM, Kallas EG, Welte A, Busch MP, Murphy G, Consortium for the Evaluation and Performance of HIV …
• Baseline CD4+ T cell counts correlates with HIV-1 synonymous rate in HLA-B*5701 subjects with different risk of disease progression.
  PLoS computational biology 2014 Norström MM, Veras NM, Huang W, Proper MC, Cook J, Hartogensis W, Hecht FM, Karlsson AC, Karlsoon AC, Salemi M
• Limited HIV infection of central memory and stem cell memory CD4+ T cells is associated with lack of progression in viremic individuals.
  PLoS pathogens 2014 Klatt NR, Bosinger SE, Peck M, Richert-Spuhler LE, Heigele A, Gile JP, Patel N, Taaffe J, Julg B, Camerini D, Torti C, Martin JN, Deeks SG, Sinclair E, Hecht FM, Lederman MM, Paiardini M, Kirchhoff F,…
• Emergence of individual HIV-specific CD8 T cell responses during primary HIV-1 infection can determine long-term disease outcome.
  Journal of virology 2014 Streeck H, Lu R, Beckwith N, Milazzo M, Liu M, Routy JP, Little S, Jessen H, Kelleher AD, Hecht F, Sekaly RP, Alter G, Heckerman D, Carrington M, Rosenberg ES, Altfeld M
• The development of an RDoC-based treatment program for adolescent depression: "Training for Awareness, Resilience, and Action" (TARA).
  Frontiers in human neuroscience 2014 Henje Blom E, Duncan LG, Ho TC, Connolly CG, LeWinn KZ, Chesney M, Hecht FM, Yang TT
• Programmed death-1 expression on CD4⁺ and CD8⁺ T cells in treated and untreated HIV disease.
  AIDS (London, England) 2014 Cockerham LR, Jain V, Sinclair E, Glidden DV, Hartogenesis W, Hatano H, Hunt PW, Martin JN, Pilcher CD, Sekaly R, McCune JM, Hecht FM, Deeks SG
• Dynamic regulation of host restriction factor expression over the course of HIV-1 infection in vivo.
  Journal of virology 2014 Raposo RA, Abdel-Mohsen M, Deng X, Hecht FM, Pilcher CD, Pillai SK, Nixon DF
• A yoga intervention for type 2 diabetes risk reduction: a pilot randomized controlled trial.
  BMC complementary and alternative medicine 2014 McDermott KA, Rao MR, Nagarathna R, Murphy EJ, Burke A, Nagendra RH, Hecht FM
• Decreased HIV type 1 transcription in CCR5-Δ32 heterozygotes during suppressive antiretroviral therapy.
  The Journal of infectious diseases 2014 Wang C, Abdel-Mohsen M, Strain MC, Lada SM, Yukl S, Cockerham LR, Pilcher CD, Hecht FM, Sinclair E, Liegler T, Richman DD, Deeks SG, Pillai SK
• Longitudinal characterization of depression and mood states beginning in primary HIV infection.
  AIDS and behavior 2014 Gold JA, Grill M, Peterson J, Pilcher C, Lee E, Hecht FM, Fuchs D, Yiannoutsos CT, Price RW, Robertson K, Spudich S
• HIV-infected individuals with low CD4/CD8 ratio despite effective antiretroviral therapy exhibit altered T cell subsets, heightened CD8+ T cell activation, and increased risk of non-AIDS morbidity and mortality.
  PLoS pathogens 2014 Serrano-Villar S, Sainz T, Lee SA, Hunt PW, Sinclair E, Shacklett BL, Ferre AL, Hayes TL, Somsouk M, Hsue PY, Van Natta ML, Meinert CL, Lederman MM, Hatano H, Jain V, Huang Y, Hecht FM, Martin JN, …
• Environmental enrichment alters splenic immune cell composition and enhances secondary influenza vaccine responses in mice.
  Molecular medicine (Cambridge, Mass.) 2014 Gurfein BT, Davidenko O, Premenko-Lanier M, Milush JM, Acree M, Dallman MF, Touma C, Palme R, York VA, Fromentin G, Darcel N, Nixon DF, Hecht FM
• Functional avidity and IL-2/perforin production is linked to the emergence of mutations within HLA-B*5701-restricted epitopes and HIV-1 disease progression.
  Journal of immunology (Baltimore, Md. : 1950) 2014 Buggert M, Norström MM, Salemi M, Hecht FM, Karlsson AC
• A randomized pilot trial of a moderate carbohydrate diet compared to a very low carbohydrate diet in overweight or obese individuals with type 2 diabetes mellitus or prediabetes.
  PloS one 2014 Saslow LR, Kim S, Daubenmier JJ, Moskowitz JT, Phinney SD, Goldman V, Murphy EJ, Cox RM, Moran P, Hecht FM
• Low proportions of CD28- CD8+ T cells expressing CD57 can be reversed by early ART initiation and predict mortality in treated HIV infection.
  The Journal of infectious diseases 2014 Lee SA, Sinclair E, Jain V, Huang Y, Epling L, Van Natta M, Meinert CL, Martin JN, McCune JM, Deeks SG, Lederman MM, Hecht FM, Hunt PW
• Impact of HIV on CD8+ T cell CD57 expression is distinct from that of CMV and aging.
  PloS one 2014 Lee SA, Sinclair E, Hatano H, Hsue PY, Epling L, Hecht FM, Bangsberg DR, Martin JN, McCune JM, Deeks SG, Hunt PW
• Trans-activation, post-transcriptional maturation, and induction of antibodies to HERV-K (HML-2) envelope transmembrane protein in HIV-1 infection.
  Retrovirology 2014 Michaud HA, de Mulder M, SenGupta D, Deeks SG, Martin JN, Pilcher CD, Hecht FM, Sacha JB, Nixon DF
• CD56negCD16⁺ NK cells are activated mature NK cells with impaired effector function during HIV-1 infection.
  Retrovirology 2013 Milush JM, López-Vergès S, York VA, Deeks SG, Martin JN, Hecht FM, Lanier LL, Nixon DF
• Correlating traditional Ayurvedic and modern medical perspectives on cancer: results of a qualitative study.
  Journal of alternative and complementary medicine (New York, N.Y.) 2013 Dhruva A, Hecht FM, Miaskowski C, Kaptchuk TJ, Bodeker G, Abrams D, Lad V, Adler SR
• Performance of rapid point-of-care and laboratory tests for acute and established HIV infection in San Francisco.
  PloS one 2013 Pilcher CD, Louie B, Facente S, Keating S, Hackett J, Vallari A, Hall C, Dowling T, Busch MP, Klausner JD, Hecht FM, Liska S, Pandori MW
• A new biomarker of hedonic eating? A preliminary investigation of cortisol and nausea responses to acute opioid blockade.
  Appetite 2013 Daubenmier J, Lustig RH, Hecht FM, Kristeller J, Woolley J, Adam T, Dallman M, Epel E
• The HIV-1 reservoir in eight patients on long-term suppressive antiretroviral therapy is stable with few genetic changes over time.
  Proceedings of the National Academy of Sciences of the United States of America 2013 Josefsson L, von Stockenstrom S, Faria NR, Sinclair E, Bacchetti P, Killian M, Epling L, Tan A, Ho T, Lemey P, Shao W, Hunt PW, Somsouk M, Wylie W, Douek DC, Loeb L, Custer J, Hoh R, Poole L, Deeks SG…
• Temporal effect of HLA-B*57 on viral control during primary HIV-1 infection.
  Retrovirology 2013 Vaidya SA, Streeck H, Beckwith N, Ghebremichael M, Pereyra F, Kwon DS, Addo MM, Rychert J, Routy JP, Jessen H, Kelleher AD, Hecht F, Sekaly RP, Carrington M, Walker BD, Allen TM, Rosenberg ES, Altfeld…
• HIV-1 Vif adaptation to human APOBEC3H haplotypes.
  Cell host & microbe 2013 Ooms M, Brayton B, Letko M, Maio SM, Pilcher CD, Hecht FM, Barbour JD, Simon V
• Activation associated ERK1/2 signaling impairments in CD8+ T cells co-localize with blunted polyclonal and HIV-1 specific effector functions in early untreated HIV-1 infection.
  PloS one 2013 Crawford TQ, Hecht FM, Pilcher CD, Ndhlovu LC, Barbour JD
• Cortisol patterns are associated with T cell activation in HIV.
  PloS one 2013 Patterson S, Moran P, Epel E, Sinclair E, Kemeny ME, Deeks SG, Bacchetti P, Acree M, Epling L, Kirschbaum C, Hecht FM
• Antiretroviral therapy initiated within 6 months of HIV infection is associated with lower T-cell activation and smaller HIV reservoir size.
  The Journal of infectious diseases 2013 Jain V, Hartogensis W, Bacchetti P, Hunt PW, Hatano H, Sinclair E, Epling L, Lee TH, Busch MP, McCune JM, Pilcher CD, Hecht FM, Deeks SG
• T cells target APOBEC3 proteins in human immunodeficiency virus type 1-infected humans and simian immunodeficiency virus-infected Indian rhesus macaques.
  Journal of virology 2013 Champiat S, Garrison KE, Raposo RA, Burwitz BJ, Reed J, Tandon R, York VA, Newman LP, Nimityongskul FA, Wilson NA, Almeida RR, Martin JN, Deeks SG, Rosenberg MG, Wiznia AA, Spotts GE, Pilcher CD, …
• Comparative analysis of measures of viral reservoirs in HIV-1 eradication studies.
  PLoS pathogens 2013 Eriksson S, Graf EH, Dahl V, Strain MC, Yukl SA, Lysenko ES, Bosch RJ, Lai J, Chioma S, Emad F, Abdel-Mohsen M, Hoh R, Hecht F, Hunt P, Somsouk M, Wong J, Johnston R, Siliciano RF, Richman DD, O'…
• Changes in seroadaptive practices from before to after diagnosis of recent HIV infection among men who have sex with men.
  PloS one 2013 Vallabhaneni S, McConnell JJ, Loeb L, Hartogensis W, Hecht FM, Grant RM, Pilcher CD
• Targeting of conserved gag-epitopes in early HIV infection is associated with lower plasma viral load and slower CD4(+) T cell depletion.
  AIDS research and human retroviruses 2013 Perez CL, Milush JM, Buggert M, Eriksson EM, Larsen MV, Liegler T, Hartogensis W, Bacchetti P, Lund O, Hecht FM, Nixon DF, Karlsson AC
• Differential expression of CD96 surface molecule represents CD8⁺ T cells with dissimilar effector function during HIV-1 infection.
  PloS one 2012 Eriksson EM, Keh CE, Deeks SG, Martin JN, Hecht FM, Nixon DF
• Cell-based measures of viral persistence are associated with immune activation and programmed cell death protein 1 (PD-1)-expressing CD4+ T cells.
  The Journal of infectious diseases 2012 Hatano H, Jain V, Hunt PW, Lee TH, Sinclair E, Do TD, Hoh R, Martin JN, McCune JM, Hecht F, Busch MP, Deeks SG
• Combination of immune and viral factors distinguishes low-risk versus high-risk HIV-1 disease progression in HLA-B*5701 subjects.
  Journal of virology 2012 Norström MM, Buggert M, Tauriainen J, Hartogensis W, Prosperi MC, Wallet MA, Hecht FM, Salemi M, Karlsson AC
• Influence of HAART on alternative reading frame immune responses over the course of HIV-1 infection.
  PloS one 2012 Champiat S, Raposo RA, Maness NJ, Lehman JL, Purtell SE, Hasenkrug AM, Miller JC, Dean H, Koff WC, Hong MA, Martin JN, Deeks SG, Spotts GE, Pilcher CD, Hecht FM, Kallas EG, Garrison KE, Nixon DF
• The association of CD4+ T-cell counts and cardiovascular risk in treated HIV disease.
  AIDS (London, England) 2012 Ho JE, Scherzer R, Hecht FM, Maka K, Selby V, Martin JN, Ganz P, Deeks SG, Hsue PY
• The calm mouse: an animal model of stress reduction.
  Molecular medicine (Cambridge, Mass.) 2012 Gurfein BT, Stamm AW, Bacchetti P, Dallman MF, Nadkarni NA, Milush JM, Touma C, Palme R, Di Borgo CP, Fromentin G, Lown-Hecht R, Konsman JP, Acree M, Premenko-Lanier M, Darcel N, Hecht FM, Nixon DF
• Hematopoietic precursor cells isolated from patients on long-term suppressive HIV therapy did not contain HIV-1 DNA.
  The Journal of infectious diseases 2012 Josefsson L, Eriksson S, Sinclair E, Ho T, Killian M, Epling L, Shao W, Lewis B, Bacchetti P, Loeb L, Custer J, Poole L, Hecht FM, Palmer S
• Yoga breathing for cancer chemotherapy-associated symptoms and quality of life: results of a pilot randomized controlled trial.
  Journal of alternative and complementary medicine (New York, N.Y.) 2012 Dhruva A, Miaskowski C, Abrams D, Acree M, Cooper B, Goodman S, Hecht FM
• The prognosis of acute low back pain in primary care in the United States: a 2-year prospective cohort study.
  Spine 2012 Mehling WE, Gopisetty V, Bartmess E, Acree M, Pressman A, Goldberg H, Hecht FM, Carey T, Avins AL
• Hematopoietic cell transplant and use of massage for improved symptom management: results from a pilot randomized control trial.
  Evidence-based complementary and alternative medicine : eCAM 2012 Mehling WE, Lown EA, Dvorak CC, Cowan MJ, Horn BN, Dunn EA, Acree M, Abrams DI, Hecht FM
• Acute low back pain and primary care: how to define recovery and chronification?
  Spine 2011 Mehling WE, Gopisetty V, Acree M, Pressman A, Carey T, Goldberg H, Hecht FM, Avins AL
• Changes in stress, eating, and metabolic factors are related to changes in telomerase activity in a randomized mindfulness intervention pilot study.
  Psychoneuroendocrinology 2011 Daubenmier J, Lin J, Blackburn E, Hecht FM, Kristeller J, Maninger N, Kuwata M, Bacchetti P, Havel PJ, Epel E
• Expansion of CD8+ T cells lacking Sema4D/CD100 during HIV-1 infection identifies a subset of T cells with decreased functional capacity.
  Blood 2011 Eriksson EM, Milush JM, Ho EL, Batista MD, Holditch SJ, Keh CE, Norris PJ, Keating SM, Deeks SG, Hunt PW, Martin JN, Rosenberg MG, Hecht FM, Nixon DF
• Mindfulness Intervention for Stress Eating to Reduce Cortisol and Abdominal Fat among Overweight and Obese Women: An Exploratory Randomized Controlled Study.
  Journal of obesity 2011 Daubenmier J, Kristeller J, Hecht FM, Maninger N, Kuwata M, Jhaveri K, Lustig RH, Kemeny M, Karan L, Epel E
• HIV-1 infection abrogates CD8+ T cell mitogen-activated protein kinase signaling responses.
  Journal of virology 2011 Crawford TQ, Ndhlovu LC, Tan A, Carvidi A, Hecht FM, Sinclair E, Barbour JD
• Mindfulness-based stress reduction for HIV treatment side effects: a randomized, wait-list controlled trial.
  Journal of pain and symptom management 2011 Duncan LG, Moskowitz JT, Neilands TB, Dilworth SE, Hecht FM, Johnson MO
• Central nervous system immune activation characterizes primary human immunodeficiency virus 1 infection even in participants with minimal cerebrospinal fluid viral burden.
  The Journal of infectious diseases 2011 Spudich S, Gisslen M, Hagberg L, Lee E, Liegler T, Brew B, Fuchs D, Tambussi G, Cinque P, Hecht FM, Price RW
• Identifying the early post-HIV antibody seroconversion period.
  The Journal of infectious diseases 2011 Hecht FM, Wellman R, Busch MP, Pilcher CD, Norris PJ, Margolick JB, Collier AC, Little SJ, Markowitz M, Routy JP, Holte S, Acute Infection Early Disease Research Program
• Strong human endogenous retrovirus-specific T cell responses are associated with control of HIV-1 in chronic infection.
  Journal of virology 2011 SenGupta D, Tandon R, Vieira RG, Ndhlovu LC, Lown-Hecht R, Ormsby CE, Loh L, Jones RB, Garrison KE, Martin JN, York VA, Spotts G, Reyes-Terán G, Ostrowski MA, Hecht FM, Deeks SG, Nixon DF
• Differential persistence of transmitted HIV-1 drug resistance mutation classes.
  The Journal of infectious diseases 2011 Jain V, Sucupira MC, Bacchetti P, Hartogensis W, Diaz RS, Kallas EG, Janini LM, Liegler T, Pilcher CD, Grant RM, Cortes R, Deeks SG, Hecht FM
• NK cells and CD1d-restricted NKT cells respond in different ways with divergent kinetics to IL-2 treatment in primary HIV-1 infection.
  Scandinavian journal of immunology 2011 Kuylenstierna C, Snyder-Cappione JE, Loo CP, Long BR, Gonzalez VD, Michaëlsson J, Moll M, Spotts G, Hecht FM, Nixon DF, Sandberg JK
• HIV disease progression correlates with the generation of dysfunctional naive CD8(low) T cells.
  Blood 2011 Favre D, Stoddart CA, Emu B, Hoh R, Martin JN, Hecht FM, Deeks SG, McCune JM
• APOBEC3H haplotypes and HIV-1 pro-viral vif DNA sequence diversity in early untreated human immunodeficiency virus-1 infection.
  Human immunology 2010 Gourraud PA, Karaouni A, Woo JM, Schmidt T, Oksenberg JR, Hecht FM, Liegler TJ, Barbour JD
• Transmitted drug resistance in persons with acute/early HIV-1 in San Francisco, 2002-2009.
  PloS one 2010 Jain V, Liegler T, Vittinghoff E, Hartogensis W, Bacchetti P, Poole L, Loeb L, Pilcher CD, Grant RM, Deeks SG, Hecht FM
• The major genetic determinants of HIV-1 control affect HLA class I peptide presentation.
  Science (New York, N.Y.) 2010 International HIV Controllers Study, Pereyra F, Jia X, McLaren PJ, Telenti A, de Bakker PI, Walker BD, Ripke S, Brumme CJ, Pulit SL, Carrington M, Kadie CM, Carlson JM, Heckerman D, Graham RR, Plenge …
• Acute HIV-1 infection: what's new? Where are we going?
  The Journal of infectious diseases 2010 D'Souza MP, Axten KL, Hecht FM, Altfeld M
• The detection of acute HIV infection.
  The Journal of infectious diseases 2010 Cohen MS, Gay CL, Busch MP, Hecht FM
• Initiation of antiretroviral therapy at higher nadir CD4+ T-cell counts is associated with reduced arterial stiffness in HIV-infected individuals.
  AIDS (London, England) 2010 Ho JE, Deeks SG, Hecht FM, Xie Y, Schnell A, Martin JN, Ganz P, Hsue PY
• IL-2 immunotherapy to recently HIV-1 infected adults maintains the numbers of IL-17 expressing CD4+ T (T(H)17) cells in the periphery.
  Journal of clinical immunology 2010 Ndhlovu LC, Sinclair E, Epling L, Tan QX, Ho T, Jha AR, Eccles-James I, Tincati C, Levy JA, Nixon DF, Hecht FM, Barbour JD
• Tryptophan catabolism by indoleamine 2,3-dioxygenase 1 alters the balance of TH17 to regulatory T cells in HIV disease.
  Science translational medicine 2010 Favre D, Mold J, Hunt PW, Kanwar B, Loke P, Seu L, Barbour JD, Lowe MM, Jayawardene A, Aweeka F, Huang Y, Douek DC, Brenchley JM, Martin JN, Hecht FM, Deeks SG, McCune JM
• The virologic and immunologic effects of cyclosporine as an adjunct to antiretroviral therapy in patients treated during acute and early HIV-1 infection.
  The Journal of infectious diseases 2010 Markowitz M, Vaida F, Hare CB, Boden D, Mohri H, Hecht FM, Kalayjian RC, Conrad A, Mildvan D, Aberg J, Hogan C, Kilby JM, Balfour HH, Schafer K, Richman D, Little S
• HIV RNA level in early infection is predicted by viral load in the transmission source.
  AIDS (London, England) 2010 Hecht FM, Hartogensis W, Bragg L, Bacchetti P, Atchison R, Grant R, Barbour J, Deeks SG
• Rapid progressing allele HLA-B35 Px restricted anti-HIV-1 CD8+ T cells recognize vestigial CTL epitopes.
  PloS one 2010 Willberg CB, Garrison KE, Jones RB, Meiklejohn DA, Spotts G, Liegler TJ, Ostrowski MA, Karlsson AC, Hecht FM, Nixon DF
• Cytomegalovirus-specific T cells persist at very high levels during long-term antiretroviral treatment of HIV disease.
  PloS one 2010 Naeger DM, Martin JN, Sinclair E, Hunt PW, Bangsberg DR, Hecht F, Hsue P, McCune JM, Deeks SG
• Immune escape mutations detected within HIV-1 epitopes associated with viral control during treatment interruption.
  Journal of acquired immune deficiency syndromes (1999) 2010 Schweighardt B, Wrin T, Meiklejohn DA, Spotts G, Petropoulos CJ, Nixon DF, Hecht FM
• HIV-Selectest enzyme immunoassay and rapid test: ability to detect seroconversion following HIV-1 infection.
  Journal of clinical microbiology 2009 Khurana S, Norris PJ, Busch MP, Haynes BF, Park S, Sasono P, Mlisana K, Salim AK, Hecht FM, Mulenga J, Chomba E, Hunter E, Allen S, Nemo G, Rodriguez-Chavez IR, Women's Interagency HIV Study …
• Lower cytokine secretion ex vivo by natural killer T cells in HIV-infected individuals is associated with higher CD161 expression.
  AIDS (London, England) 2009 Snyder-Cappione JE, Loo CP, Carvalho KI, Kuylenstierna C, Deeks SG, Hecht FM, Rosenberg MG, Sandberg JK, Kallas EG, Nixon DF
• Characterization of human immunodeficiency virus type 1 populations containing CXCR4-using variants from recently infected individuals.
  AIDS research and human retroviruses 2009 Huang W, Toma J, Stawiski E, Fransen S, Wrin T, Parkin N, Whitcomb JM, Coakley E, Hecht FM, Deeks SG, Gandhi RT, Eshleman SH, Petropoulos CJ
• Transcriptional errors in human immunodeficiency virus type 1 generate targets for T-cell responses.
  Clinical and vaccine immunology : CVI 2009 Garrison KE, Champiat S, York VA, Agrawal AT, Kallas EG, Martin JN, Hecht FM, Deeks SG, Nixon DF
• HIV-1-specific T Cell-dependent natural killer (NK) cell activation: major contribution by NK cells to interferon-gamma production in response to HIV-1 antigens.
  AIDS research and human retroviruses 2009 Loo CP, Long BR, Hecht FM, Nixon DF, Michaëlsson J
• Human immunodeficiency virus type 1-specific CD8+ T-cell responses during primary infection are major determinants of the viral set point and loss of CD4+ T cells.
  Journal of virology 2009 Streeck H, Jolin JS, Qi Y, Yassine-Diab B, Johnson RC, Kwon DS, Addo MM, Brumme C, Routy JP, Little S, Jessen HK, Kelleher AD, Hecht FM, Sekaly RP, Rosenberg ES, Walker BD, Carrington M, Altfeld M
• Body awareness: construct and self-report measures.
  PloS one 2009 Mehling WE, Gopisetty V, Daubenmier J, Price CJ, Hecht FM, Stewart A
• Incomplete peripheral CD4+ cell count restoration in HIV-infected patients receiving long-term antiretroviral treatment.
  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2009 Kelley CF, Kitchen CM, Hunt PW, Rodriguez B, Hecht FM, Kitahata M, Crane HM, Willig J, Mugavero M, Saag M, Martin JN, Deeks SG
• Tolerability and efficacy of PI versus NNRTI-based regimens in subjects receiving HAART during acute or early HIV infection.
  Journal of acquired immune deficiency syndromes (1999) 2009 Apuzzo LG, Vaida F, Gallant JE, Ernstrom KB, Little SJ, Routy JP, Collier AC, Conway B, Markowitz MH, Hecht FM, Walker BD, Connick E, Margolick JB
• High CD8+ T cell activation marks a less differentiated HIV-1 specific CD8+ T cell response that is not altered by suppression of viral replication.
  PloS one 2009 Barbour JD, Ndhlovu LC, Xuan Tan Q, Ho T, Epling L, Bredt BM, Levy JA, Hecht FM, Sinclair E
• CD8+ cell anti-HIV activity rapidly increases upon discontinuation of early antiretroviral therapy.
  Journal of clinical immunology 2009 Killian MS, Roop J, Ng S, Hecht FM, Levy JA
• Tim-3 expression defines a novel population of dysfunctional T cells with highly elevated frequencies in progressive HIV-1 infection.
  The Journal of experimental medicine 2008 Jones RB, Ndhlovu LC, Barbour JD, Sheth PM, Jha AR, Long BR, Wong JC, Satkunarajah M, Schweneker M, Chapman JM, Gyenes G, Vali B, Hyrcza MD, Yue FY, Kovacs C, Sassi A, Loutfy M, Halpenny R, Persad D, …
• Immunity to HIV-1 is influenced by continued natural exposure to exogenous virus.
  PLoS pathogens 2008 Willberg CB, McConnell JJ, Eriksson EM, Bragg LA, York VA, Liegler TJ, Hecht FM, Grant RM, Nixon DF
• Prevalence of oral disease among adults with primary HIV infection.
  Oral diseases 2008 Owotade FJ, Shiboski CH, Poole L, Ramstead CA, Malvin K, Hecht FM, Greenspan JS
• Stimulant use is associated with immune activation and depleted tryptophan among HIV-positive persons on anti-retroviral therapy.
  Brain, behavior, and immunity 2008 Carrico AW, Johnson MO, Morin SF, Remien RH, Riley ED, Hecht FM, Fuchs D
• Comparison of algorithms that interpret genotypic HIV-1 drug resistance to determine the prevalence of transmitted drug resistance.
  AIDS (London, England) 2008 Liu L, May S, Richman DD, Hecht FM, Markowitz M, Daar ES, Routy JP, Margolick JB, Collier AC, Woelk CH, Little SJ, Smith DM
• CCL3L1-CCR5 genotype influences durability of immune recovery during antiretroviral therapy of HIV-1-infected individuals.
  Nature medicine 2008 Ahuja SK, Kulkarni H, Catano G, Agan BK, Camargo JF, He W, O'Connell RJ, Marconi VC, Delmar J, Eron J, Clark RA, Frost S, Martin J, Ahuja SS, Deeks SG, Little S, Richman D, Hecht FM, Dolan MJ
• Conferral of enhanced natural killer cell function by KIR3DS1 in early human immunodeficiency virus type 1 infection.
  Journal of virology 2008 Long BR, Ndhlovu LC, Oksenberg JR, Lanier LL, Hecht FM, Nixon DF, Barbour JD
• Assessment of rapid tests for detection of human immunodeficiency virus-specific antibodies in recently infected individuals.
  Journal of clinical microbiology 2008 Louie B, Wong E, Klausner JD, Liska S, Hecht F, Dowling T, Obeso M, Phillips SS, Pandori MW
• Clinical presentation and diagnosis of primary HIV-1 infection.
  Current opinion in HIV and AIDS 2008 Daar ES, Pilcher CD, Hecht FM
• Immune reconstitution of CD56(dim) NK cells in individuals with primary HIV-1 infection treated with interleukin-2.
  The Journal of infectious diseases 2008 Michaëlsson J, Long BR, Loo CP, Lanier LL, Spotts G, Hecht FM, Nixon DF
• Elevated frequency of gamma interferon-producing NK cells in healthy adults vaccinated against influenza virus.
  Clinical and vaccine immunology : CVI 2007 Long BR, Michaelsson J, Loo CP, Ballan WM, Vu BA, Hecht FM, Lanier LL, Chapman JM, Nixon DF
• FOXP3 expressing CD127lo CD4+ T cells inversely correlate with CD38+ CD8+ T cell activation levels in primary HIV-1 infection.
  Journal of leukocyte biology 2007 Ndhlovu LC, Loo CP, Spotts G, Nixon DF, Hecht FM
• T cell responses to human endogenous retroviruses in HIV-1 infection.
  PLoS pathogens 2007 Garrison KE, Jones RB, Meiklejohn DA, Anwar N, Ndhlovu LC, Chapman JM, Erickson AL, Agrawal A, Spotts G, Hecht FM, Rakoff-Nahoum S, Lenz J, Ostrowski MA, Nixon DF
• CCL3L1 and CCR5 influence cell-mediated immunity and affect HIV-AIDS pathogenesis via viral entry-independent mechanisms.
  Nature immunology 2007 Dolan MJ, Kulkarni H, Camargo JF, He W, Smith A, Anaya JM, Miura T, Hecht FM, Mamtani M, Pereyra F, Marconi V, Mangano A, Sen L, Bologna R, Clark RA, Anderson SA, Delmar J, O'Connell RJ, Lloyd A, …
• Loss of T cell responses following long-term cryopreservation.
  Journal of immunological methods 2007 Owen RE, Sinclair E, Emu B, Heitman JW, Hirschkorn DF, Epling CL, Tan QX, Custer B, Harris JM, Jacobson MA, McCune JM, Martin JN, Hecht FM, Deeks SG, Norris PJ
• Antiretroviral drug therapy alters the profile of human immunodeficiency virus type 1-specific T-cell responses and shifts the immunodominant cytotoxic T-lymphocyte response from Gag to Pol.
  Journal of virology 2007 Karlsson AC, Chapman JM, Heiken BD, Hoh R, Kallas EG, Martin JN, Hecht FM, Deeks SG, Nixon DF
• The relation between symptoms, viral load, and viral load set point in primary HIV infection.
  Journal of acquired immune deficiency syndromes (1999) 2007 Kelley CF, Barbour JD, Hecht FM
• Frequent detection of the parvoviruses, PARV4 and PARV5, in plasma from blood donors and symptomatic individuals.
  Transfusion 2007 Fryer JF, Delwart E, Hecht FM, Bernardin F, Jones MS, Shah N, Baylis SA
• Quantitative longitudinal analysis of T cell receptor repertoire expression in HIV-infected patients on antiretroviral and interleukin-2 therapy.
  AIDS research and human retroviruses 2007 Sriram U, Wong M, Caillier SJ, Hecht FM, Elkins MK, Levy JA, Oksenberg JR, Baranzini SE
• Synergy or independence? Deciphering the interaction of HLA Class I and NK cell KIR alleles in early HIV-1 disease progression.
  PLoS pathogens 2007 Barbour JD, Sriram U, Caillier SJ, Levy JA, Hecht FM, Oksenberg JR
• Human immunodeficiency virus type 1 (HIV-1)-specific CD8+ T(EMRA) cells in early infection are linked to control of HIV-1 viremia and predict the subsequent viral load set point.
  Journal of virology 2007 Northfield JW, Loo CP, Barbour JD, Spotts G, Hecht FM, Klenerman P, Nixon DF, Michaëlsson J
• Lessons from an HIV transmission pair.
  The Journal of infectious diseases 2007 Hecht FM, Wolf LE, Lo B
• Symptom management with massage and acupuncture in postoperative cancer patients: a randomized controlled trial.
  Journal of pain and symptom management 2007 Mehling WE, Jacobs B, Acree M, Wilson L, Bostrom A, West J, Acquah J, Burns B, Chapman J, Hecht FM
• Sequential broadening of CTL responses in early HIV-1 infection is associated with viral escape.
  PloS one 2007 Karlsson AC, Iversen AK, Chapman JM, de Oliviera T, Spotts G, McMichael AJ, Davenport MP, Hecht FM, Nixon DF
• Lessons from primary HIV infection.
  Focus (San Francisco, Calif.) 2007 Hecht F, Pilcher C
• Frequent methamphetamine use is associated with primary non-nucleoside reverse transcriptase inhibitor resistance.
  AIDS (London, England) 2007 Colfax GN, Vittinghoff E, Grant R, Lum P, Spotts G, Hecht FM
• Physicians' communication with patients about adherence to HIV medication in San Francisco and Copenhagen: a qualitative study using Grounded Theory.
  BMC health services research 2006 Barfod TS, Hecht FM, Rubow C, Gerstoft J
• Microbial translocation is a cause of systemic immune activation in chronic HIV infection.
  Nature medicine 2006 Brenchley JM, Price DA, Schacker TW, Asher TE, Silvestri G, Rao S, Kazzaz Z, Bornstein E, Lambotte O, Altmann D, Blazar BR, Rodriguez B, Teixeira-Johnson L, Landay A, Martin JN, Hecht FM, Picker LJ, …
• Greater CD4 T-cell gains after one year of antiretroviral therapy are associated with lower HIV-1 pol replication capacity.
  AIDS (London, England) 2006 Barbour JD, Hecht FM, Little SJ, Markowitz M, Daar ES, Kelleher AD, Routy JP, Campbell TB, Rosenberg ES, Segal MR, Weidler J, Grant RM
• Human immunodeficiency virus type 1 Vpr induces DNA replication stress in vitro and in vivo.
  Journal of virology 2006 Zimmerman ES, Sherman MP, Blackett JL, Neidleman JA, Kreis C, Mundt P, Williams SA, Warmerdam M, Kahn J, Hecht FM, Grant RM, de Noronha CM, Weyrich AS, Greene WC, Planelles V
• A multicenter observational study of the potential benefits of initiating combination antiretroviral therapy during acute HIV infection.
  The Journal of infectious diseases 2006 Hecht FM, Wang L, Collier A, Little S, Markowitz M, Margolick J, Kilby JM, Daar E, Conway B, Holte S, AIEDRP Network
• Elevations in IL-10, TNF-alpha, and IFN-gamma from the earliest point of HIV Type 1 infection.
  AIDS research and human retroviruses 2006 Norris PJ, Pappalardo BL, Custer B, Spotts G, Hecht FM, Busch MP
• A piece of my mind. The CBC.
  JAMA 2006 Hecht FM
• The effects of early antiretroviral therapy and its discontinuation on the HIV-specific antibody response.
  AIDS research and human retroviruses 2006 Killian MS, Norris PJ, Rawal BD, Lebedeva M, Hecht FM, Levy JA, Busch MP
• Similar changes in plasmacytoid dendritic cell and CD4 T-cell counts during primary HIV-1 infection and treatment.
  AIDS (London, England) 2006 Killian MS, Fujimura SH, Hecht FM, Levy JA
• Neutralizing antibody responses against autologous and heterologous viruses in acute versus chronic human immunodeficiency virus (HIV) infection: evidence for a constraint on the ability of HIV to completely evade neutralizing antibody responses.
  Journal of virology 2006 Deeks SG, Schweighardt B, Wrin T, Galovich J, Hoh R, Sinclair E, Hunt P, McCune JM, Martin JN, Petropoulos CJ, Hecht FM
• Newly diagnosed HIV infection.
  The New England journal of medicine 2006 Chin-Hong PV, Hecht FM, Klausner JD
• Seroreversion in subjects receiving antiretroviral therapy during acute/early HIV infection.
  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2006 Hare CB, Pappalardo BL, Busch MP, Karlsson AC, Phelps BH, Alexander SS, Bentsen C, Ramstead CA, Nixon DF, Levy JA, Hecht FM
• Expansion of CD1d-restricted NKT cells in patients with primary HIV-1 infection treated with interleukin-2.
  Blood 2005 Moll M, Snyder-Cappione J, Spotts G, Hecht FM, Sandberg JK, Nixon DF
• Seroconversion following nonoccupational postexposure prophylaxis against HIV.
  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2005 Roland ME, Neilands TB, Krone MR, Katz MH, Franses K, Grant RM, Busch MP, Hecht FM, Shacklett BL, Kahn JO, Bamberger JD, Coates TJ, Chesney MA, Martin JN
• Potential herpesvirus interaction during HIV type 1 primary infection.
  AIDS research and human retroviruses 2005 Lennette ET, Busch MP, Hecht FM, Levy JA
• Resistance testing in drug-naive HIV-infected patients: is it time?
  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2005 Hecht FM, Grant RM
• Nucleic acid amplification testing for diagnosis of acute HIV infection: has the time come?
  AIDS (London, England) 2005 Busch MP, Hecht FM
• New DNA viruses identified in patients with acute viral infection syndrome.
  Journal of virology 2005 Jones MS, Kapoor A, Lukashov VV, Simmonds P, Hecht F, Delwart E
• Randomized, controlled trial of breath therapy for patients with chronic low-back pain.
  Alternative therapies in health and medicine 2005 Mehling WE, Hamel KA, Acree M, Byl N, Hecht FM
• Bias control in trials of bodywork: a review of methodological issues.
  Journal of alternative and complementary medicine (New York, N.Y.) 2005 Mehling WE, DiBlasi Z, Hecht F
• Longitudinal analysis of B cell repertoire and antibody gene rearrangements during early HIV infection.
  Genes and immunity 2005 Elkins MK, Vittinghoff E, Baranzini SE, Hecht FM, Sriram U, Busch MP, Levy JA, Oksenberg JR, San Francisco Primary Infection Group
• Interleukin-2 therapy restores CD8 cell non-cytotoxic anti-HIV responses in primary infection subjects receiving HAART.
  AIDS (London, England) 2004 Martinez-Mariño B, Shiboski S, Hecht FM, Kahn JO, Levy JA
• Persistence of primary drug resistance among recently HIV-1 infected adults.
  AIDS (London, England) 2004 Barbour JD, Hecht FM, Wrin T, Liegler TJ, Ramstead CA, Busch MP, Segal MR, Petropoulos CJ, Grant RM
• Expansion of CD7(low) and CD7(negative) CD8 T-cell effector subsets in HIV-1 infection: correlation with antigenic load and reversion by antiretroviral treatment.
  Blood 2004 Aandahl EM, Quigley MF, Moretto WJ, Moll M, Gonzalez VD, Sönnerborg A, Lindbäck S, Hecht FM, Deeks SG, Rosenberg MG, Nixon DF, Sandberg JK
• Higher CD4+ T cell counts associated with low viral pol replication capacity among treatment-naive adults in early HIV-1 infection.
  The Journal of infectious diseases 2004 Barbour JD, Hecht FM, Wrin T, Segal MR, Ramstead CA, Liegler TJ, Busch MP, Petropoulos CJ, Hellmann NS, Kahn JO, Grant RM
• Immune activation set point during early HIV infection predicts subsequent CD4+ T-cell changes independent of viral load.
  Blood 2004 Deeks SG, Kitchen CM, Liu L, Guo H, Gascon R, Narváez AB, Hunt P, Martin JN, Kahn JO, Levy J, McGrath MS, Hecht FM
• Effect of IL-2 therapy on CD8+ cell noncytotoxic anti-HIV response during primary HIV-1 infection.
  Journal of clinical immunology 2004 Martinez-Mariño B, Ashlock BM, Shiboski S, Hecht FM, Levy JA
• Human CD4+ CD25+ regulatory T cells control T-cell responses to human immunodeficiency virus and cytomegalovirus antigens.
  Journal of virology 2004 Aandahl EM, Michaëlsson J, Moretto WJ, Hecht FM, Nixon DF
• Influence of HLA-B57 on clinical presentation and viral control during acute HIV-1 infection.
  AIDS (London, England) 2003 Altfeld M, Addo MM, Rosenberg ES, Hecht FM, Lee PK, Vogel M, Yu XG, Draenert R, Johnston MN, Strick D, Allen TM, Feeney ME, Kahn JO, Sekaly RP, Levy JA, Rockstroh JK, Goulder PJ, Walker BD
• Development of a new less-sensitive enzyme immunoassay for detection of early HIV-1 infection.
  Journal of acquired immune deficiency syndromes (1999) 2003 Rawal BD, Degula A, Lebedeva L, Janssen RS, Hecht FM, Sheppard HW, Busch MP
• Absolute or total lymphocyte count as a marker for the CD4 T lymphocyte criterion for initiating antiretroviral therapy.
  AIDS (London, England) 2003 Jacobson MA, Liu L, Khayam-Bashi H, Deeks SG, Hecht FM, Kahn J
• Greater reversal of CD4+ cell abnormalities and viral load reduction after initiation of antiretroviral therapy with zidovudine, lamivudine, and nelfinavir before complete HIV type 1 seroconversion.
  AIDS research and human retroviruses 2003 Smith DE, Kaufmann GR, Kahn JO, Hecht FM, Grey PA, Zaunders JJ, Cunningham PH, Carr A, Duncombe C, Quan DC, Petersen A, Cooper DA
• HIV testing within at-risk populations in the United States and the reasons for seeking or avoiding HIV testing.
  Journal of acquired immune deficiency syndromes (1999) 2002 Kellerman SE, Lehman JS, Lansky A, Stevens MR, Hecht FM, Bindman AB, Wortley PM
• Time trends in primary HIV-1 drug resistance among recently infected persons.
  JAMA 2002 Grant RM, Hecht FM, Warmerdam M, Liu L, Liegler T, Petropoulos CJ, Hellmann NS, Chesney M, Busch MP, Kahn JO
• Use of laboratory tests and clinical symptoms for identification of primary HIV infection.
  AIDS (London, England) 2002 Hecht FM, Busch MP, Rawal B, Webb M, Rosenberg E, Swanson M, Chesney M, Anderson J, Levy J, Kahn JO
• HIV expertise: a roundtable.
  AIDS clinical care 2001 Boswell SL, Hecht FM, Powderly WG, Soloway B, Volberding PA
• Relative dominance of epitope-specific cytotoxic T-lymphocyte responses in human immunodeficiency virus type 1-infected persons with shared HLA alleles.
  Journal of virology 2001 Day CL, Shea AK, Altfeld MA, Olson DP, Buchbinder SP, Hecht FM, Rosenberg ES, Walker BD, Kalams SA
• Improving on a coin toss to predict patient adherence to medications.
  Annals of internal medicine 2001 Turner BJ, Hecht FM
• Provider assessment of adherence to HIV antiretroviral therapy.
  Journal of acquired immune deficiency syndromes (1999) 2001 Bangsberg DR, Hecht FM, Clague H, Charlebois ED, Ciccarone D, Chesney M, Moss A
• Cellular immune responses and viral diversity in individuals treated during acute and early HIV-1 infection.
  The Journal of experimental medicine 2001 Altfeld M, Rosenberg ES, Shankarappa R, Mukherjee JS, Hecht FM, Eldridge RL, Addo MM, Poon SH, Phillips MN, Robbins GK, Sax PE, Boswell S, Kahn JO, Brander C, Goulder PJ, Levy JA, Mullins JI, Walker …
• Reduction in CD8+ cell noncytotoxic anti-HIV activity in individuals receiving highly active antiretroviral therapy during primary infection.
  Proceedings of the National Academy of Sciences of the United States of America 2001 Stranford SA, Ong JC, Martinez-Marino B, Busch M, Hecht FM, Kahn J, Levy JA
• Longitudinal analysis of T-cell receptor gene use by CD8(+) T cells in early human immunodeficiency virus infection in patients receiving highly active antiretroviral therapy.
  Blood 2001 Schito AM, Vittinghoff E, Hecht FM, Elkins MK, Kahn JO, Levy JA, Oksenberg JR
• Why does Pneumocystis carinii pneumonia still occur?
  AIDS (London, England) 2000 Huang L, Hecht FM
• Does HIV reporting by name deter testing? MESH Study Group.
  AIDS (London, England) 2000 Hecht FM, Chesney MA, Lehman JS, Osmond D, Vranizan K, Colman S, Keane D, Reingold A, Bindman AB
• Adherence to protease inhibitors, HIV-1 viral load, and development of drug resistance in an indigent population.
  AIDS (London, England) 2000 Bangsberg DR, Hecht FM, Charlebois ED, Zolopa AR, Holodniy M, Sheiner L, Bamberger JD, Chesney MA, Moss A
• Quantitative and cost comparison of ultrasensitive human immunodeficiency virus type 1 RNA viral load assays: Bayer bDNA quantiplex versions 3.0 and 2.0 and Roche PCR Amplicor monitor version 1.5.
  Journal of clinical microbiology 2000 Elbeik T, Charlebois E, Nassos P, Kahn J, Hecht FM, Yajko D, Ng V, Hadley K
• Name-based surveillance and public health interventions for persons with HIV infection. Multistate Evaluation of Surveillance for HIV Study Group.
  Annals of internal medicine 1999 Osmond DH, Bindman AB, Vranizan K, Lehman JS, Hecht FM, Keane D, Reingold A
• Optimizing care for persons with HIV infection. Society of General Internal Medicine AIDS Task Force.
  Annals of internal medicine 1999 Hecht FM, Wilson IB, Wu AW, Cook RL, Turner BJ
• Antiretrovirals for HIV nephropathy?
  AIDS clinical care 1999 Saag M, Hecht F
• HIV RNA and CD4 cell count response to protease inhibitor therapy in an urban AIDS clinic: response to both initial and salvage therapy.
  AIDS (London, England) 1999 Deeks SG, Hecht FM, Swanson M, Elbeik T, Loftus R, Cohen PT, Grant RM
• Adherence: a necessity for successful HIV combination therapy.
  AIDS (London, England) 1999 Chesney MA, Ickovics J, Hecht FM, Sikipa G, Rabkin J
• Postexposure prophylaxis after nonoccupational HIV exposure: clinical, ethical, and policy considerations.
  JAMA 1998 Lurie P, Miller S, Hecht F, Chesney M, Lo B
• Multistate evaluation of anonymous HIV testing and access to medical care. Multistate Evaluation of Surveillance of HIV (MESH) Study Group.
  JAMA 1998 Bindman AB, Osmond D, Hecht FM, Lehman JS, Vranizan K, Keane D, Reingold A
• Measuring HIV treatment adherence in clinical practice.
  AIDS clinical care 1998 Hecht FM
• Sexual transmission of an HIV-1 variant resistant to multiple reverse-transcriptase and protease inhibitors.
  The New England journal of medicine 1998 Hecht FM, Grant RM, Petropoulos CJ, Dillon B, Chesney MA, Tian H, Hellmann NS, Bandrapalli NI, Digilio L, Branson B, Kahn JO
• New testing strategy to detect early HIV-1 infection for use in incidence estimates and for clinical and prevention purposes.
  JAMA 1998 Janssen RS, Satten GA, Stramer SL, Rawal BD, O'Brien TR, Weiblen BJ, Hecht FM, Jack N, Cleghorn FR, Kahn JO, Chesney MA, Busch MP
• Itraconazole maintenance treatment for histoplasmosis in AIDS: a prospective, multicenter trial.
  Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association 1997 Hecht FM, Wheat J, Korzun AH, Hafner R, Skahan KJ, Larsen R, Limjoco MT, Simpson M, Schneider D, Keefer MC, Clark R, Lai KK, Jacobson JM, Squires K, Bartlett JA, Powderly W
• Protease inhibitors in the homeless.
  JAMA 1997 Bangsberg D, Tulsky JP, Hecht FM, Moss AR
• [Reevaluation of surgical treatment of cancers of the anus. Therapeutic proposals based on an experience with 33 patients].
  Chirurgie; memoires de l'Academie de chirurgie 1997 Benhamou G, Opsahl S, Vinardi O, Hecht F, Vilotte J
• A new focus on primary HIV infection.
  AIDS clinical care 1996 Hecht F
• Murder of son with a genital malformation.
  American journal of medical genetics 1995 Hecht BK, Hecht F
• Suspected Pneumocystis carinii pneumonia with a negative induced sputum examination. Is early bronchoscopy useful?
  American journal of respiratory and critical care medicine 1995 Huang L, Hecht FM, Stansell JD, Montanti R, Hadley WK, Hopewell PC
• CD4+ T-lymphocyte measures in the treatment of individuals infected with human immunodeficiency virus type 1. A review for clinical practitioners.
  Archives of internal medicine 1994 Turner BJ, Hecht FM, Ismail RB
• Preventive health care for adults with HIV infection.
  JAMA 1993 Jewett JF, Hecht FM
• H. influenzae vaccines in HIV.
  The New England journal of medicine 1992 Hecht FM
• The quality and influence of JAMA.
  JAMA 1988 Hecht F
• Clinical and biologic characterization of T-cell neoplasias with rearrangements of chromosome 7 band q34.
  Blood 1988 Smith SD, Morgan R, Gemmell R, Amylon MD, Link MP, Linker C, Hecht BK, Warnke R, Glader BE, Hecht F
• A cytogenetical analysis in patients with secondary hematological disorders.
  Haematologica 1987 Zaccaria A, Alimena G, Billström R, Carbonell F, Castoldi GL, Fuscaldo K, Gastaldi R, Hecht F, Mitelman F, Hossfeld DK
• Mutations of the Kirsten-ras proto-oncogene in human preleukaemia.
  Nature 1987 Liu E, Hjelle B, Morgan R, Hecht F, Bishop JM
• Lymphocyte subpopulation profiles and mitogen kinetics in immunological deficiency testing.
  Journal of clinical immunology 1987 Radvany RM, Schubert MS, Kiamar M, Jarzabek V, Koehler-Carone K, Kuban D, Hecht F
• Counseling the HIV-positive woman regarding pregnancy.
  JAMA 1987 Hecht F
• Cytogenetic analyses in 89 patients with secondary hematologic disorders--results of a cooperative study.
  Cancer genetics and cytogenetics 1987 Zaccaria A, Alimena G, Baccarani M, Billström R, Carbonell F, Castoldi GL, Fuscaldo K, Hecht F, Hossfeld DK, Mitelman F
• "I accuse" the Journal of unfair journalism.
  The New England journal of medicine 1987 Hecht F
• Chromosome changes connect immunodeficiency and cancer in ataxia-telangiectasia.
  The American journal of pediatric hematology/oncology 1987 Hecht F, Hecht BK
• Chromosome 9 abnormalities in childhood T-cell leukemia.
  The New England journal of medicine 1986 Smith SD, Link MP, Trela M, Amylon M, Sklar J, Morgan R, Hecht F
• Chromosome 5q35 breakpoint in malignant histiocytosis.
  The New England journal of medicine 1986 Morgan R, Hecht BK, Sandberg AA, Hecht F, Smith SD
• Responses of hemopoietic precursors to 13-cis retinoic acid and 1,25 dihydroxyvitamin D3 in the myelodysplastic syndromes.
  Blood 1986 Swanson G, Picozzi V, Morgan R, Hecht F, Greenberg P
• Cytogenetic and immunophenotypic analysis of cell lines established from patients with T cell leukemia/lymphoma.
  Blood 1986 Smith SD, Morgan R, Link MP, McFall P, Hecht F
• Leukemia with Down's syndrome: translocation between chromosomes 1 and 19 in acute myelomonocytic leukemia following transient congenital myeloproliferative syndrome.
  Blood 1985 Morgan R, Hecht F, Cleary ML, Sklar J, Link MP
• Translocations in T-cell leukemia and lymphoma.
  The New England journal of medicine 1985 Hecht F, Morgan R, Gemmill RM, Hecht BK
• Caution about chorionic villi sampling in the first trimester.
  The New England journal of medicine 1984 Hecht F, Hecht BK, Bixenman HA
• Antibiotics containing trimethoprim and the fragile X chromosome.
  The New England journal of medicine 1983 Hecht F, Glover TW
• Immunoglobulin expression in Burkitt's lymphoma and leukemia.
  The New England journal of medicine 1982 Hecht F, Kaiser-McCaw B
• The physician as a risk factor in midtrimester amniocentesis.
  The New England journal of medicine 1982 Hecht F
• A surgical approach to the treatment of fetal hydrocephalus.
  The New England journal of medicine 1982 Clewell WH, Johnson ML, Meier PR, Newkirk JB, Zide SL, Hendee RW, Bowes WA, Hecht F, O'Keeffe D, Henry GP, Shikes RH
• Placement of ventriculo-amniotic shunt for hydrocephalus in a fetus.
  The New England journal of medicine 1981 Clewell WH, Johnson ML, Meier PR, Newkirk JB, Hendee RW, Bowes WA, Zide SL, Hecht F, Henry G, O'Keeffe D
• Chromosome translocations in cancer.
  The New England journal of medicine 1981 Hecht F, Kaiser-McCaw B, Sandberg AA
• Position effect in 8;14 translocation in Burkitt's lymphoma.
  The New England journal of medicine 1981 Hecht F, Kaiser-McCaw B
• Prenatal diagnosis: a broader perspective.
  JAMA 1980 Hecht F
• The decline of NIH's peer-review system?
  The New England journal of medicine 1979 Hecht F
• Linkage group I: multipoint mapping.
  Birth defects original article series 1975 Meyers DA, Conneally PM, Hecht F, Lovrien EW, Magenis E, Merritt AD, Palmer CG, Rivas ML, Wang L
• Linkage group I: multipoint mapping.
  Cytogenetics and cell genetics 1975 Meyers DA, Conneally PM, Hecht F, Lovrien EW, Magenis E, Merritt AD, Palmer GC, Rivas ML, Wang L
• Linkage relationships of 1qh to Amy, Fy, PGM1, and Rh.
  Birth defects original article series 1975 Rivas ML, Conneally PM, Hecht F, Lovrien EW, Magenis E, Merritt AD, Meyers DA, Palmer CG, Wang L
• Linkage relationships of 1qh to Amy, Fy, PGM1, and Rh.
  Cytogenetics and cell genetics 1975 Rivas ML, Conneally PM, Hecht F, Lovrien EW, Magenis E, Merritt AD, Meyers DA, Palmer CG, Wang L