Fraser Conrad, MS
Project and Policy Manager
Dean's Office
School of Medicine

Education & Training

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• MS Healthcare Administration and Interprofessional Leadership UCSF 09/2017
• School of Medicine Leadership Development Program UCSF 08/2015
• BS Health Sciences University of Oklahoma 05/2001

Publications (16)

Top publication keywords:
Antibodies, MonoclonalAntibodiesAntigens, SurfaceAntitoxinsSingle-Chain AntibodiesClostridium botulinumEpitopesFlow CytometryAntigens, NeoplasmPeptide LibraryBotulinum Toxins, Type ABotulismBotulinum ToxinsAntibodies, NeutralizingIntercellular Adhesion Molecule-1

• A Three-Monoclonal Antibody Combination Potently Neutralizes BoNT/G Toxin in Mice.
  Toxins 2023 Fan Y, Lou J, Tam CC, Wen W, Conrad F, Leal da Silva Alves P, Cheng LW, Garcia-Rodriguez C, Farr-Jones S, Marks JD
• Multicolor fluorescence activated cell sorting to generate humanized monoclonal antibody binding seven subtypes of BoNT/F.
  PloS one 2022 Fan Y, Sun Z, Conrad F, Wen W, Zhao L, Lou J, Zhou Y, Farr-Jones S, Marks JD
• A Four-Monoclonal Antibody Combination Potently Neutralizes Multiple Botulinum Neurotoxin Serotypes C and D.
  Toxins 2021 Garcia-Rodriguez C, Yan S, Geren IN, Knopp KA, Dong J, Sun Z, Lou J, Conrad F, Wen WH, Farr-Jones S, Smith TJ, Brown JL, Skerry JC, Smith LA, Marks JD
• The Novel Clostridial Neurotoxin Produced by Strain IBCA10-7060 Is Immunologically Equivalent to BoNT/HA.
  Toxins 2019 Fan Y, Barash JR, Conrad F, Lou J, Tam C, Cheng LW, Arnon SS, Marks JD
• A Three Monoclonal Antibody Combination Potently Neutralizes Multiple Botulinum Neurotoxin Serotype E Subtypes.
  Toxins 2018 Garcia-Rodriguez C, Razai A, Geren IN, Lou J, Conrad F, Wen WH, Farr-Jones S, Smith TJ, Brown JL, Skerry JC, Smith LA, Marks JD

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• A Single Tri-Epitopic Antibody Virtually Recapitulates the Potency of a Combination of Three Monoclonal Antibodies in Neutralization of Botulinum Neurotoxin Serotype A.
  Toxins 2018 Lou J, Wen W, Conrad F, Meng Q, Dong J, Sun Z, Garcia-Rodriguez C, Farr-Jones S, Cheng LW, Henderson TD, Brown JL, Smith TJ, Smith LA, Cormier A, Marks JD
• A three monoclonal antibody combination potently neutralizes multiple botulinum neurotoxin serotype F subtypes.
  PloS one 2017 Fan Y, Garcia-Rodriguez C, Lou J, Wen W, Conrad F, Zhai W, Smith TJ, Smith LA, Marks JD
• Immunological Characterization and Neutralizing Ability of Monoclonal Antibodies Directed Against Botulinum Neurotoxin Type H.
  The Journal of infectious diseases 2016 Fan Y, Barash JR, Lou J, Conrad F, Marks JD, Arnon SS
• Monoclonal Antibodies that Inhibit the Proteolytic Activity of Botulinum Neurotoxin Serotype/B.
  Toxins 2015 Fan Y, Dong J, Lou J, Wen W, Conrad F, Geren IN, Garcia-Rodriguez C, Smith TJ, Smith LA, Ho M, Pires-Alves M, Wilson BA, Marks JD
• Monoclonal Antibodies Targeting the Alpha-Exosite of Botulinum Neurotoxin Serotype/A Inhibit Catalytic Activity.
  PloS one 2015 Fan Y, Geren IN, Dong J, Lou J, Wen W, Conrad F, Smith TJ, Smith LA, Ho M, Pires-Alves M, Wilson BA, Marks JD
• Impact of intrinsic affinity on functional binding and biological activity of EGFR antibodies.
  Molecular cancer therapeutics 2012 Zhou Y, Goenaga AL, Harms BD, Zou H, Lou J, Conrad F, Adams GP, Schoeberl B, Nielsen UB, Marks JD
• A single-domain llama antibody potently inhibits the enzymatic activity of botulinum neurotoxin by binding to the non-catalytic alpha-exosite binding region.
  Journal of molecular biology 2010 Dong J, Thompson AA, Fan Y, Lou J, Conrad F, Ho M, Pires-Alves M, Wilson BA, Stevens RC, Marks JD
• Human antibodies targeting cell surface antigens overexpressed by the hormone refractory metastatic prostate cancer cells: ICAM-1 is a tumor antigen that mediates prostate cancer cell invasion.
  Journal of molecular medicine (Berlin, Germany) 2009 Conrad F, Zhu X, Zhang X, Chalkley RJ, Burlingame AL, Marks JD, Liu B
• Anti-CD166 single chain antibody-mediated intracellular delivery of liposomal drugs to prostate cancer cells.
  Molecular cancer therapeutics 2007 Roth A, Drummond DC, Conrad F, Hayes ME, Kirpotin DB, Benz CC, Marks JD, Liu B
• Recombinant full-length human IgG1s targeting hormone-refractory prostate cancer.
  Journal of molecular medicine (Berlin, Germany) 2007 Liu B, Conrad F, Roth A, Drummond DC, Simko JP, Marks JD
• Mapping tumor epitope space by direct selection of single-chain Fv antibody libraries on prostate cancer cells.
  Cancer research 2004 Liu B, Conrad F, Cooperberg MR, Kirpotin DB, Marks JD