Franziska Plessow, PhD
Associate Professor
Psychiatry
School of Medicine

Dr. Franziska Plessow is a cognitive neuroscientist and Associate Professor in the Department of Psychiatry and Behavioral Sciences at the University of California, San Francisco.

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She directs the ADAPT Lab (Advancing Discovery in Adaptability, Plasticity, and Therapeutics) and serves as Scientific Domain Lead for Noninvasive Brain Stimulation and Cognitive Phenotyping within the Translational Psychedelic Research Program. Dr. Plessow studies the biological substrates and cognitive processes that underlie cognitive control — the capacities that align behavior with current goals and anticipated demands. Her lab conducts mechanistic, multimodal studies that integrate carefully validated cognitive paradigms with neuroendocrine and neuroimmune assays, pharmacologic and noninvasive brain-stimulation probes, neuroimaging, and computational modeling to map when control adapts — or fails to adapt — to acute and chronic perturbations. One program identifies biological determinants and liabilities of adaptive control across internal and external contexts; a second examines how control dysregulation contributes to psychopathology. Her goal is to translate mechanistic insights into biomarker-anchored precision diagnostics and interventions that improve risk stratification, prevention, and treatment across conditions marked by control dysregulation, including stress-related disorders, eating and weight disorders, attention-deficit/hyperactivity disorder, and obesity.

Awards

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  • Travel Award for Presentation at the 50th Annual Meeting of the Psychonomic Society, Association of Friends and Sponsors of Technische Universität Dresden
  • Charles A. King Trust Research Fellowship Award, Charles A. King Trust
  • Women in Medicine Research Scholar Award, Department of Medicine, Massachusetts General Hospital
  • Award for Outstanding Diplom-Psychologin Degree (MS equivalent), Department of Psychology, Humboldt-Universität zu Berlin
  • Award for Excellence in Teaching (awarded twice), Department of Psychology, Technische Universität Dresden
  • Dissertation Award for Outstanding Doctoral Thesis, Department of Psychology, Technische Universität Dresden
  • Young Investigator Start-Up Award (awarded twice), Department of Psychology, Technische Universität Dresden
  • Fellowship Award for Research Visit at Duke University and City University of New York, G. A. Lienert Foundation
  • Full Merit-Based Scholarship for BS and MS Studies, German Academic Scholarship Foundation
  • International Scholarship for Study and Research at the University of Glasgow, German Academic Scholarship Foundation
  • Louis V. Gerstner III Research Scholar Award, Gerstner Family Foundation / Department of Psychiatry, Massachusetts General Hospital
  • MGH Department of Medicine Fellowship Award, Eleanor & Miles Shore Program for Scholars in Medicine, Harvard Medical School
  • Faculty Award, Harvard Mind Brain Behavior Interfaculty Initiative, Harvard University
  • Outstanding Manuscript Award, Nutrition Obesity Research Center at Harvard
  • Elected Fellow, Psychonomic Society
  • Young Investigator Award, Women in Endocrinology

Education & Training

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  • Applied Biostatistics Biostatistics Harvard Medical School
  • Postdoctoral Research Fellowship Clinical and Translational Neuroscience (Neurology) Harvard Medical School
  • BS and MS (Diplom-Psychologin) Psychology Humboldt-Universität zu Berlin
  • PhD (Dr. rer. nat.) Psychology (Biological and Cognitive) Technische Universität Dresden

Interests

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  • Neuromodulation
  • Transcranial Magnetic Stimulation (TMS)
  • Hypothalamic–Pituitary–Gonadal (HPG) Axis
  • Inhibitory Control
  • Metabolic Signaling
  • Cognitive Flexibility
  • Executive Functions
  • Neuroimaging
  • Stress
  • Attention-Deficit/Hyperactivity Disorder (ADHD)
  • Neuroimmune
  • Neuroendocrine
  • Cognitive Control
  • Eating Disorders
  • Hypothalamic–Pituitary–Adrenal (HPA) Axis

Publications (99)

Top publication keywords:
OxytocinAttentionFeeding and Eating DisordersStress, PsychologicalAdministration, IntranasalHydrocortisoneGhrelinSalivaPituitary-Adrenal SystemHypothalamo-Hypophyseal SystemGoalsAnorexia NervosaExecutive FunctionCognitionOverweight

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