Seyedeh Faranak Fattahi, PhD
Assistant Professor
Cellular Molecular Pharmacology
School of Medicine

Publications (30)

Top publication keywords:
Hyperlipoproteinemia Type IIHirschsprung DiseaseCell Culture TechniquesPatient AcuityCell TransplantationEnteric Nervous SystemAndrogensOrganoidsNeural CrestCell LineageDiabetic NeuropathiesSmad ProteinsPluripotent Stem CellsIntestine, SmallDrug Discovery

• Deriving Schwann cells from hPSCs enables disease modeling and drug discovery for diabetic peripheral neuropathy.
  Cell stem cell 2023 Majd H, Amin S, Ghazizadeh Z, Cesiulis A, Arroyo E, Lankford K, Majd A, Farahvashi S, Chemel AK, Okoye M, Scantlen MD, Tchieu J, Calder EL, Le Rouzic V, Shibata B, Arab A, Goodarzi H, Pasternak G, …
• Generation of Schwann cell derived melanocytes from hPSCs identifies pro-metastatic factors in melanoma.
  bioRxiv : the preprint server for biology 2023 Samuel RM, Navickas A, Maynard A, Gaylord EA, Garcia K, Bhat S, Majd H, Richter MN, Elder N, Le D, Nguyen P, Shibata B, Llabata ML, Selleri L, Laird DJ, Darmanis S, Goodarzi H, Fattahi F
• Programming multicellular assembly with synthetic cell adhesion molecules.
  Nature 2022 Stevens AJ, Harris AR, Gerdts J, Kim KH, Trentesaux C, Ramirez JT, McKeithan WL, Fattahi F, Klein OD, Fletcher DA, Lim WA
• Diseased, differentiated and difficult: Strategies for improved engineering of in vitro neurological systems.
  Frontiers in cellular neuroscience 2022 Elder N, Fattahi F, McDevitt TC, Zholudeva LV
• Stem Cell-Based Models for Studying the Effects of Cancer and Cancer Therapies on the Peripheral Nervous System.
  Advanced biology 2022 Richter MN, Fattahi F

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• Androgens increase excitement in brain organoid research.
  Cell stem cell 2022 Samuel RM, Majd H, Richter MN, Fattahi F
• A dual SHOX2:GFP; MYH6:mCherry knockin hESC reporter line for derivation of human SAN-like cells.
  iScience 2022 Ghazizadeh Z, Zhu J, Fattahi F, Tang A, Sun X, Amin S, Tsai SY, Khalaj M, Zhou T, Samuel RM, Zhang T, Ortega FA, Gordillo M, Moroziewicz D, NYSCF Global Stem Cell Array® Team, Paull D, Noggle SA, …
• 5-Fluorouracil: A Narrative Review on the Role of Regulatory Mechanisms in Driving Resistance to This Chemotherapeutic Agent.
  Frontiers in oncology 2021 Ghafouri-Fard S, Abak A, Tondro Anamag F, Shoorei H, Fattahi F, Javadinia SA, Basiri A, Taheri M
• The interaction between miRNAs/lncRNAs and nuclear factor-κB (NF-κB) in human disorders.
  Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Ghafouri-Fard S, Abak A, Fattahi F, Hussen BM, Bahroudi Z, Shoorei H, Taheri M
• Surface Proteomics Reveals CD72 as a Target for In Vitro-Evolved Nanobody-Based CAR-T Cells in KMT2A/MLL1-Rearranged B-ALL.
  Cancer discovery 2021 Nix MA, Mandal K, Geng H, Paranjape N, Lin YT, Rivera JM, Marcoulis M, White KL, Whitman JD, Bapat SP, Parker KR, Ramirez J, Deucher A, Phojanokong P, Steri V, Fattahi F, Hann BC, Satpathy AT, Manglik…
• Prospective Isolation of ISL1+ Cardiac Progenitors from Human ESCs for Myocardial Infarction Therapy.
  Stem cell reports 2021 Ghazizadeh Z, Fattahi F, Mirzaei M, Bayersaikhan D, Lee J, Chae S, Hwang D, Byun K, Tabar MS, Taleahmad S, Mirshahvaladi S, Shabani P, Fonoudi H, Haynes PA, Baharvand H, Aghdami N, Evans T, Lee B, …
• Human Induced Pluripotent Stem Cell Derived Sensory Neurons are Sensitive to the Neurotoxic Effects of Paclitaxel.
  Clinical and translational science 2020 Xiong C, Chua KC, Stage TB, Priotti J, Kim J, Altman-Merino A, Chan D, Saraf K, Canato Ferracini A, Fattahi F, Kroetz DL
• Androgen Signaling Regulates SARS-CoV-2 Receptor Levels and Is Associated with Severe COVID-19 Symptoms in Men.
  Cell stem cell 2020 Samuel RM, Majd H, Richter MN, Ghazizadeh Z, Zekavat SM, Navickas A, Ramirez JT, Asgharian H, Simoneau CR, Bonser LR, Koh KD, Garcia-Knight M, Tassetto M, Sunshine S, Farahvashi S, Kalantari A, Liu W,…
• Androgen Regulates SARS-CoV-2 Receptor Levels and Is Associated with Severe COVID-19 Symptoms in Men.
  bioRxiv : the preprint server for biology 2020 Ghazizadeh Z, Majd H, Richter M, Samuel R, Zekavat SM, Asgharian H, Farahvashi S, Kalantari A, Ramirez J, Zhao H, Natarajan P, Goodarzi H, Fattahi F
• Roadmap for the Emerging Field of Cancer Neuroscience.
  Cell 2020 Monje M, Borniger JC, D'Silva NJ, Deneen B, Dirks PB, Fattahi F, Frenette PS, Garzia L, Gutmann DH, Hanahan D, Hervey-Jumper SL, Hondermarck H, Hurov JB, Kepecs A, Knox SM, Lloyd AC, Magnon C, Saloman…
• Generation of Knockout Gene-Edited Human Intestinal Organoids.
  Methods in molecular biology (Clifton, N.J.) 2020 Rajendra C, Wald T, Barber K, Spence JR, Fattahi F, Klein OD
• Derivation of enteric neuron lineages from human pluripotent stem cells.
  Nature protocols 2019 Barber K, Studer L, Fattahi F
• HSP90-incorporating chaperome networks as biosensor for disease-related pathways in patient-specific midbrain dopamine neurons.
  Nature communications 2018 Kishinevsky S, Wang T, Rodina A, Chung SY, Xu C, Philip J, Taldone T, Joshi S, Alpaugh ML, Bolaender A, Gutbier S, Sandhu D, Fattahi F, Zimmer B, Shah SK, Chang E, Inda C, Koren J, Saurat NG, Leist M,…
• Prospective Isolation of ISL1+ Cardiac Progenitors from Human ESCs for Myocardial Infarction Therapy.
  Stem cell reports 2018 Ghazizadeh Z, Fattahi F, Mirzaei M, Bayersaikhan D, Lee J, Chae S, Hwang D, Byun K, Tabar MS, Taleahmad S, Mirshahvaladi S, Shabani P, Fonoudi H, Haynes PA, Baharvand H, Aghdami N, Evans T, Lee B, …
• A Modular Platform for Differentiation of Human PSCs into All Major Ectodermal Lineages.
  Cell stem cell 2017 Tchieu J, Zimmer B, Fattahi F, Amin S, Zeltner N, Chen S, Studer L
• Combined small-molecule inhibition accelerates the derivation of functional cortical neurons from human pluripotent stem cells.
  Nature biotechnology 2017 Qi Y, Zhang XJ, Renier N, Wu Z, Atkin T, Sun Z, Ozair MZ, Tchieu J, Zimmer B, Fattahi F, Ganat Y, Azevedo R, Zeltner N, Brivanlou AH, Karayiorgou M, Gogos J, Tomishima M, Tessier-Lavigne M, Shi SH, …
• Capturing the biology of disease severity in a PSC-based model of familial dysautonomia.
  Nature medicine 2016 Zeltner N, Fattahi F, Dubois NC, Saurat N, Lafaille F, Shang L, Zimmer B, Tchieu J, Soliman MA, Lee G, Casanova JL, Studer L
• Deriving human ENS lineages for cell therapy and drug discovery in Hirschsprung disease.
  Nature 2016 Fattahi F, Steinbeck JA, Kriks S, Tchieu J, Zimmer B, Kishinevsky S, Zeltner N, Mica Y, El-Nachef W, Zhao H, de Stanchina E, Gershon MD, Grikscheit TC, Chen S, Studer L
• Isolation and characterization of cardiogenic, stem-like cardiac precursors from heart samples of patients with congenital heart disease.
  Life sciences 2015 Ghazizadeh Z, Vahdat S, Fattahi F, Fonoudi H, Omrani G, Gholampour M, Aghdami N
• Neural Crest Cells from Dual SMAD Inhibition.
  Current protocols in stem cell biology 2015 Fattahi F, Studer L, Tomishima MJ
• Feeder-free derivation of neural crest progenitor cells from human pluripotent stem cells.
  Journal of visualized experiments : JoVE 2014 Zeltner N, Lafaille FG, Fattahi F, Studer L
• Ankyloglossia and tongue mobility.
  European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry 2013 Jamilian A, Fattahi FH, Kootanayi NG
• Disease-corrected hepatocyte-like cells from familial hypercholesterolemia-induced pluripotent stem cells.
  Molecular biotechnology 2013 Fattahi F, Asgari S, Pournasr B, Seifinejad A, Totonchi M, Taei A, Aghdami N, Salekdeh GH, Baharvand H
• ISL1 protein transduction promotes cardiomyocyte differentiation from human embryonic stem cells.
  PloS one 2013 Fonoudi H, Yeganeh M, Fattahi F, Ghazizadeh Z, Rassouli H, Alikhani M, Mojarad BA, Baharvand H, Salekdeh GH, Aghdami N
• Comprehensive gene expression analysis of human embryonic stem cells during differentiation into neural cells.
  PloS one 2011 Fathi A, Hatami M, Hajihosseini V, Fattahi F, Kiani S, Baharvand H, Salekdeh GH