Eugene Ozhinsky, PhD
Associate Professor
Radiology
School of Medicine
eugene.ozhinsky@ucsf.edu 415-353-4932
Eugene Ozhinsky, PhD is an Associate Professor in the Department of Radiology and Biomedical Imaging, University of California San Francisco. His main research interests are in the areas of machine learning for musculoskeletal imaging and MR-guided focused ultrasound therapy.
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He is working at the VA Advanced Imaging Research Center (VAARC, part of San Francisco Veterans Affairs Health Care System) on development and implementation of machine learning techniques for automated image processing, analysis, and prescription of musculoskeletal X-ray, MRI, PET, and CT images. The goal of this work is to improve care for the VA patient population by enabling precise diagnostics, prediction of disease progression, as well as response to therapy.
As a Technical Director for Focused Ultrasound at the Department of Radiology and Biomedical Imaging, Dr. Ozhinsky is supporting clinical focused ultrasound treatments of patients with neurological and oncological conditions. His current research focuses on safely and effectively opening of blood-brain barrier to enable delivery of therapeutics to the brain.
Dr. Ozhinsky has obtained his PhD in the UC Berkeley/UCSF Joint Graduate Program in Bioengineering. His dissertation work was on automated acquisition of brain magnetic resonance spectroscopy data.
Awards
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- Outstanding Poster Presentation Award, 13th Annual Imaging Research Symposium, UCSF, 2016
- Magna Cum Laude Merit Award, International Society for Magnetic Resonance in Medicine, 2014
- Surbeck Scholar Award (1st place), INDNJC Foundation, 2011
- Graduate Dean's Health Science Fellowship, UCSF, 2006
Education & Training
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- Ph.D. Graduate Division (Bioengineering) University of California, San Francisco 2012
Interests
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- MRI pulse sequence development
- MR-guided high intensity focused ultrasound
- Image-guided therapy
- Machine learning
- MR thermometry
Websites
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- Focused Ultrasound Lab (radiology.ucsf.edu)
- Automated Prescription for Brain 3D MRSI software (open source) (sourceforge.net)
- Automated Prescription for Brain 3D MRSI (open source) (github.com)
Grants and Projects
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- Rapid, High-Resolution, Fully-Automated Metabolic Imaging for Evaluating Patients with Glioma, Department of Defense CDMRP, 2023-2027
- Development of Methods for Precise MR-guided Hyperthermia Delivery for Targeted Cancer Therapies, NIH, 2019-2021
Publications (36)
Top publication keywords:
Fibromatosis, AggressiveThermometryOrgan MotionLow Back PainThermographyMagnetic Resonance ImagingPhantoms, ImagingImaging, Three-DimensionalImage Processing, Computer-AssistedMagnetic Resonance SpectroscopyMotionMachine LearningLumbar VertebraeHyperthermia, InducedHigh-Intensity Focused Ultrasound Ablation
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Machine learning-based automated scan prescription of lumbar spine MRI acquisitions.
Magnetic resonance imaging 2024 Ozhinsky E, Liu F, Pedoia V, Majumdar S -
Technical advances in motion-robust MR thermometry.
Magnetic resonance in medicine 2024 Kim K, Narsinh K, Ozhinsky E -
Motion-robust, multi-slice, real-time MR thermometry for MR-guided thermal therapy in abdominal organs.
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 2023 Kim K, Diederich C, Narsinh K, Ozhinsky E -
Sonication strategies toward volumetric ultrasound hyperthermia treatment using the ExAblate body MRgFUS system.
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 2021 Kim K, Zubair M, Adams M, Diederich CJ, Ozhinsky E -
Development and Validation of a Multitask Deep Learning Model for Severity Grading of Hip Osteoarthritis Features on Radiographs.
Radiology 2020 von Schacky CE, Sohn JH, Liu F, Ozhinsky E, Jungmann PM, Nardo L, Posadzy M, Foreman SC, Nevitt MC, Link TM, Pedoia V -
MR thermometry-guided ultrasound hyperthermia of user-defined regions using the ExAblate prostate ablation array.
Journal of therapeutic ultrasound 2018 Ozhinsky E, Salgaonkar VA, Diederich CJ, Rieke V -
T2-based temperature monitoring in bone marrow for MR-guided focused ultrasound.
Journal of therapeutic ultrasound 2016 Ozhinsky E, Han M, Bucknor M, Krug R, Rieke V -
T2-based temperature monitoring in abdominal fat during MR-guided focused ultrasound treatment of patients with uterine fibroids.
Journal of therapeutic ultrasound 2015 Ozhinsky E, Kohi MP, Ghanouni P, Rieke V -
Automated prescription of oblique brain 3D magnetic resonance spectroscopic imaging.
Magnetic resonance in medicine 2012 Ozhinsky E, Vigneron DB, Chang SM, Nelson SJ
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Monitoring Blood-Brain Barrier Opening in Rats with a Preclinical Focused Ultrasound System.
Journal of visualized experiments : JoVE 2024 Kim K, Gallus M, Xiao T, Parchure AS, Shah BR, Okada H, Diederich C, Ozhinsky E, Narsinh K -
Volumetric hyperthermia delivery using the ExAblate Body MR-guided focused ultrasound system.
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 2024 Kim K, Gupta P, Narsinh K, Diederich CJ, Ozhinsky E -
Shape-recovery of implanted shape-memory devices remotely triggered via image-guided ultrasound heating.
Nature communications 2024 Zhu Y, Deng K, Zhou J, Lai C, Ma Z, Zhang H, Pan J, Shen L, Bucknor MD, Ozhinsky E, Kim S, Chen G, Ye SH, Zhang Y, Liu D, Gao C, Xu Y, Wang H, Wagner WR -
MR Thermometry during Transcranial MR Imaging-Guided Focused Ultrasound Procedures: A Review.
AJNR. American journal of neuroradiology 2023 Mattay RR, Kim K, Shah L, Shah B, Sugrue L, Safoora F, Ozhinsky E, Narsinh KH -
Estimate of fetal brain temperature using proton resonance frequency thermometry during 3 Tesla fetal magnetic resonance imaging.
Quantitative imaging in medicine and surgery 2023 Ellison J, Kim K, Li Y, Mu X, Glenn O, Ozhinsky E, Peyvandi S, Xu D -
MR-guided focused ultrasound therapy of extra-abdominal desmoid tumors: a multicenter retrospective study of 105 patients.
European radiology 2023 Düx DM, Baal JD, Bitton R, Chen J, Brunsing RL, Sheth VR, Rosenberg J, Kim K, Ozhinsky E, Avedian R, Ganjoo K, Bucknor M, Dobrotwir A, Ghanouni P -
Magnetic Resonance Imaging of the Lumbar Spine: Recommendations for Acquisition and Image Evaluation from the BACPAC Spine Imaging Working Group.
Pain medicine (Malden, Mass.) 2023 Sollmann N, Fields AJ, O'Neill C, Nardo L, Majumdar S, Chin CT, Tosun D, Han M, Vu AT, Ozhinsky E, Shah LM, Harris RE, Lobo R, Anderst W, Herzog R, Psioda MA, Standaert CJ, Price RT, Lotz JC, Link TM,… -
Technical note: Low-cost MR-compatible pneumatic respiratory organ motion simulator for the development of MR-guided thermal therapy.
Medical physics 2022 Kim K, Jones P, Diederich C, Ozhinsky E -
Studying osteoarthritis with artificial intelligence applied to magnetic resonance imaging.
Nature reviews. Rheumatology 2021 Calivà F, Namiri NK, Dubreuil M, Pedoia V, Ozhinsky E, Majumdar S -
Anatomic thermochromic tissue-mimicking phantom of the lumbar spine for pre-clinical evaluation of MR-guided focused ultrasound (MRgFUS) ablation of the facet joint.
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 2021 Zhang W, Trivedi H, Adams M, Losey AD, Diederich CJ, Ozhinsky E, Rieke V, Bucknor MD -
Computer-Aided Detection AI Reduces Interreader Variability in Grading Hip Abnormalities With MRI.
Journal of magnetic resonance imaging : JMRI 2020 Tibrewala R, Ozhinsky E, Shah R, Flament I, Crossley K, Srinivasan R, Souza R, Link TM, Pedoia V, Majumdar S -
Automatic Hip Fracture Identification and Functional Subclassification with Deep Learning.
Radiology. Artificial intelligence 2020 Krogue JD, Cheng KV, Hwang KM, Toogood P, Meinberg EG, Geiger EJ, Zaid M, McGill KC, Patel R, Sohn JH, Wright A, Darger BF, Padrez KA, Ozhinsky E, Majumdar S, Pedoia V -
Wireless Resonant Circuits Printed Using Aerosol Jet Deposition for MRI Catheter Tracking.
IEEE transactions on bio-medical engineering 2019 Jordan CD, Thorne BRH, Wadhwa A, Losey AD, Ozhinsky E, Kondapavulur S, Fratello V, Moore T, Stillson C, Yee C, Watkins RD, Scott GC, Martin AJ, Zhang X, Wilson MW, Hetts SW -
The impact of technical parameters on ablation volume during MR-guided focused ultrasound of desmoid tumors.
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 2019 Bucknor MD, Beroukhim G, Rieke V, Ozhinsky E, Lobach I -
T2 mapping as a predictor of nonperfused volume in MRgFUS treatment of desmoid tumors.
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 2019 Morochnik S, Ozhinsky E, Rieke V, Bucknor MD -
Effect of Sonication Duration and Power on Ablation Depth During MR-Guided Focused Ultrasound of Bone.
Journal of magnetic resonance imaging : JMRI 2017 Bucknor MD, Ozhinsky E, Shah R, Krug R, Rieke V -
Quantifying temperature-dependent T1 changes in cortical bone using ultrashort echo-time MRI.
Magnetic resonance in medicine 2015 Han M, Rieke V, Scott SJ, Ozhinsky E, Salgaonkar VA, Jones PD, Larson PE, Diederich CJ, Krug R -
Short-echo three-dimensional H-1 MR spectroscopic imaging of patients with glioma at 7 Tesla for characterization of differences in metabolite levels.
Journal of magnetic resonance imaging : JMRI 2014 Li Y, Larson P, Chen AP, Lupo JM, Ozhinsky E, Kelley D, Chang SM, Nelson SJ -
Model-based feasibility assessment and evaluation of prostate hyperthermia with a commercial MR-guided endorectal HIFU ablation array.
Medical physics 2014 Salgaonkar VA, Prakash P, Rieke V, Ozhinsky E, Plata J, Kurhanewicz J, Hsu IC, Diederich CJ -
Strategies for rapid in vivo 1H and hyperpolarized 13C MR spectroscopic imaging.
Journal of magnetic resonance (San Diego, Calif. : 1997) 2013 Nelson SJ, Ozhinsky E, Li Y, Park Iw, Crane J -
Prospective image registration for automated scan prescription of follow-up knee images in quantitative studies.
Magnetic resonance imaging 2011 Goldenstein J, Schooler J, Crane JC, Ozhinsky E, Pialat JB, Carballido-Gamio J, Majumdar S -
Improved spatial coverage for brain 3D PRESS MRSI by automatic placement of outer-volume suppression saturation bands.
Journal of magnetic resonance imaging : JMRI 2011 Ozhinsky E, Vigneron DB, Nelson SJ -
Volumetric cartilage measurements of porcine knee at 1.5-T and 3.0-T MR imaging: evaluation of precision and accuracy.
Radiology 2006 Bauer JS, Krause SJ, Ross CJ, Krug R, Carballido-Gamio J, Ozhinsky E, Majumdar S, Link TM -
Computer-aided quantification of focal cartilage lesions of osteoarthritic knee using MRI.
Magnetic resonance imaging 2004 Lee KY, Dunn TC, Steinbach LS, Ozhinsky E, Ries MD, Majumdar S -
A new computational efficient approach for trabecular bone analysis using beam models generated with skeletonized graph technique.
Computer methods in biomechanics and biomedical engineering 2004 Pothuaud L, Van Rietbergen B, Charlot C, Ozhinsky E, Majumdar S -
A three-dimensional MRI analysis of knee kinematics.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2004 Patel VV, Hall K, Ries M, Lotz J, Ozhinsky E, Lindsey C, Lu Y, Majumdar S -
Magnetic resonance imaging of patellofemoral kinematics with weight-bearing.
The Journal of bone and joint surgery. American volume 2003 Patel VV, Hall K, Ries M, Lindsey C, Ozhinsky E, Lu Y, Majumdar S