Esteban G. Burchard, MD, MPH
Professor
Bioengineering
School of Pharmacy

I am passionate about understanding why and how the risk of disease and drug response vary by race and genetic ancestry.

I led a diverse international cross-functional team of ~ 60 physicians, pharmacists, and scientists to elucidate this empiric clinical and biomedical question.

I spearheaded cross-sectional and longitudinal clinical studies in racially/ethnically diverse populations. This effort required establishing national and international physician-scientist networks, community, stakeholder, patient engagement, pre- and post-study launch strategies, execution, management, and analysis.

We collected clinical, social, and environmental data from more than 16,000 African American, Puerto Rican, and Mexican participants. I directed incorporating clinical and biomedical data from minority populations for large-scale data analysis, technology, and AI development. I have more than 370 peer-reviewed publications, 100% focused on minority populations, and generated over $100 million dollars to study racial, ethnic, and genetic ancestry differences in disease risk and drug response.

I provided the NIH and the global scientific community with the most racially diverse clinical and biological data from African American, Puerto Rican, and Mexican populations worldwide. Results from these data have placed us at the epicenter of the international debate on race and genetic ancestry in medicine.

I have outstanding oral and written communication skills and can effectively communicate complex and racially significant clinical and scientific concepts.

I am committed to leveraging my belief in leadership, teamwork, and resiliency to contribute to clinical and biomedical research.

This body of work epitomizes my ongoing drive to use science to improve the care of minority patients and mentorship of physicians, scientists, and students to improve diversity, equity, and inclusion in science and medicine.

Visit my lab page to learn more: https://pharm.ucsf.edu/burchard.

• Advancing genomics to improve health equity.
  Nature genetics 2024 Madden EB, Hindorff LA, Bonham VL, Akintobi TH, Burchard EG, Baker KE, Begay RL, Carpten JD, Cox NJ, Di Francesco V, Dillard DA, Fletcher FE, Fullerton SM, Garrison NA, Hammack-Aviran CM, Hiratsuka VY…
• The Puerto Rican Infant Metagenomic and Epidemiologic Study of Respiratory Outcomes (PRIMERO): Design and Baseline Characteristics for a Birth Cohort Study of Early-life Viral Respiratory Illnesses and Airway Dysfunction in Puerto Rican Children.
  medRxiv : the preprint server for health sciences 2024 Witonsky JI, Elhawary JR, Eng C, Oh SS, Salazar S, Contreras MG, Medina V, Secor EA, Zhang P, Everman JL, Fairbanks-Mahnke A, Pruesse E, Sajuthi SP, Chang CH, Guerrero TR, Fuentes KC, Lopez N, …
• A noncoding regulatory variant in IKZF1 increases acute lymphoblastic leukemia risk in Hispanic/Latino children.
  Cell genomics 2024 de Smith AJ, Wahlster L, Jeon S, Kachuri L, Black S, Langie J, Cato LD, Nakatsuka N, Chan TF, Xia G, Mazumder S, Yang W, Gazal S, Eng C, Hu D, Burchard EG, Ziv E, Metayer C, Mancuso N, Yang JJ, Ma X, …
• Novel insights into the whole-blood DNA methylome of asthma in ethnically diverse children and youth.
  The European respiratory journal 2023 Herrera-Luis E, Rosa-Baez C, Huntsman S, Eng C, Beckman KB, LeNoir MA, Rodriguez-Santana JR, Villar J, Laprise C, Borrell LN, Ziv E, Burchard EG, Pino-Yanes M
• European and multi-ancestry genome-wide association meta-analysis of atopic dermatitis highlights importance of systemic immune regulation.
  Nature communications 2023 Budu-Aggrey A, Kilanowski A, Sobczyk MK, 23andMe Research Team, Shringarpure SS, Mitchell R, Reis K, Reigo A, Estonian Biobank Research Team, Mägi R, Nelis M, Tanaka N, Brumpton BM, Thomas LF, Sole-…
• Epigenomic response to albuterol treatment in asthma-relevant airway epithelial cells.
  Clinical epigenetics 2023 Perez-Garcia J, Pino-Yanes M, Plender EG, Everman JL, Eng C, Jackson ND, Moore CM, Beckman KB, Medina V, Sharma S, Winnica DE, Holguin F, Rodríguez-Santana J, Villar J, Ziv E, Seibold MA, Burchard EG
• Race/Ethnicity and Clinical Prediction Algorithms for Childhood Asthma.
  NEJM evidence 2023 Witonsky J, Burchard EG
• WHOLE GENOME SEQUENCING ANALYSIS OF BODY MASS INDEX IDENTIFIES NOVEL AFRICAN ANCESTRY-SPECIFIC RISK ALLELE.
  medRxiv : the preprint server for health sciences 2023 Zhang X, Brody JA, Graff M, Highland HM, Chami N, Xu H, Wang Z, Ferrier K, Chittoor G, Josyula NS, Li X, Li Z, Allison MA, Becker DM, Bielak LF, Bis JC, Boorgula MP, Bowden DW, Broome JG, Buth EJ, …
• Human genetics influences microbiome composition involved in asthma exacerbations despite inhaled corticosteroid treatment.
  The Journal of allergy and clinical immunology 2023 Perez-Garcia J, Espuela-Ortiz A, Hernández-Pérez JM, González-Pérez R, Poza-Guedes P, Martin-Gonzalez E, Eng C, Sardón-Prado O, Mederos-Luis E, Corcuera-Elosegui P, Sánchez-Machín I, Korta-Murua J, …
• Gene expression in African Americans, Puerto Ricans and Mexican Americans reveals ancestry-specific patterns of genetic architecture.
  Nature genetics 2023 Kachuri L, Mak ACY, Hu D, Eng C, Huntsman S, Elhawary JR, Gupta N, Gabriel S, Xiao S, Keys KL, Oni-Orisan A, Rodríguez-Santana JR, LeNoir MA, Borrell LN, Zaitlen NA, Williams LK, Gignoux CR, Burchard …
• Multi-omic approach associates blood methylome with bronchodilator drug response in pediatric asthma.
  The Journal of allergy and clinical immunology 2023 Perez-Garcia J, Herrera-Luis E, Li A, Mak ACY, Huntsman S, Oh SS, Elhawary JR, Eng C, Beckman KB, Hu D, Lorenzo-Diaz F, Lenoir MA, Rodriguez-Santana J, Zaitlen N, Villar J, Borrell LN, Burchard EG, …
• Phenotypic subtyping via contrastive learning.
  bioRxiv : the preprint server for biology 2023 Gorla A, Sankararaman S, Burchard E, Flint J, Zaitlen N, Rahmani E
• Ancestral risk modification for multiple sclerosis susceptibility detected across the Major Histocompatibility Complex in a multi-ethnic population.
  PloS one 2022 Beecham AH, Amezcua L, Chinea A, Manrique CP, Gomez L, Martinez A, Beecham GW, Patsopoulos NA, Chitnis T, Weiner HL, De Jager PL, Burchard EG, Lund BT, Fitzgerald KC, Calabresi PA, Delgado SR, …
• Differences in Self-Reported Food Allergy and Food-Associated Anaphylaxis by Race and Ethnicity Among SAPPHIRE Cohort Participants.
  The journal of allergy and clinical immunology. In practice 2022 Xiao S, Sahasrabudhe N, Yang M, Hu D, Sleiman P, Hochstadt S, Cabral W, Gilliland F, Gauderman WJ, Martinez F, Hakonarson H, Kumar R, Burchard EG, Williams LK
• Author Correction: Nasal airway transcriptome-wide association study of asthma reveals genetically driven mucus pathobiology.
  Nature communications 2022 Sajuthi SP, Everman JL, Jackson ND, Saef B, Rios CL, Moore CM, Mak ACY, Eng C, Fairbanks-Mahnke A, Salazar S, Elhawary J, Huntsman S, Medina V, Nickerson DA, Germer S, Zody MC, Abecasis G, Kang HM, …
• Admixture mapping of severe asthma exacerbations in Hispanic/Latino children and youth.
  Thorax 2022 Herrera-Luis E, Mak ACY, Perez-Garcia J, Martin-Gonzalez E, Eng C, Beckman KB, Huntsman S, Hu D, González-Pérez R, Hernández-Pérez JM, Mederos-Luis E, Sio YY, Poza-Guedes P, Sardón O, Corcuera P, …
• Association of bronchial steroid inducible methylation quantitative trait loci with asthma and chronic obstructive pulmonary disease treatment response.
  Clinical and translational allergy 2022 Slob EMA, Faiz A, van Nijnatten J, Vijverberg SJH, Longo C, Kutlu M, Chew FT, Sio YY, Herrera-Luis E, Espuela-Ortiz A, Perez-Garcia J, Pino-Yanes M, Burchard EG, Potocnik U, Gorenjak M, Palmer C, …
• Genome-wide association study in minority children with asthma implicates DNAH5 in bronchodilator responsiveness.
  Scientific reports 2022 Joo J, Mak ACY, Xiao S, Sleiman PM, Hu D, Huntsman S, Eng C, Kan M, Diwakar AR, Lasky-Su JA, Weiss ST, Sordillo JE, Wu AC, Cloutier M, Canino G, Forno E, Celedón JC, Seibold MA, Hakonarson H, Williams…
• Multi-ancestry genome-wide association study of asthma exacerbations.
  Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology 2022 Herrera-Luis E, Ortega VE, Ampleford EJ, Sio YY, Granell R, de Roos E, Terzikhan N, Vergara EE, Hernandez-Pacheco N, Perez-Garcia J, Martin-Gonzalez E, Lorenzo-Diaz F, Hashimoto S, Brinkman P, U-…
• Clotting factor genes are associated with preeclampsia in high-altitude pregnant women in the Peruvian Andes.
  American journal of human genetics 2022 Nieves-Colón MA, Badillo Rivera KM, Sandoval K, Villanueva Dávalos V, Enriquez Lencinas LE, Mendoza-Revilla J, Adhikari K, González-Buenfil R, Chen JW, Zhang ET, Sockell A, Ortiz-Tello P, Hurtado GM, …
• Methylation risk scores for childhood aeroallergen sensitization: Results from the LISA birth cohort.
  Allergy 2022 Kilanowski A, Chen J, Everson T, Thiering E, Wilson R, Gladish N, Waldenberger M, Zhang H, Celedón JC, Burchard EG, Peters A, Standl M, Hüls A
• Nasal airway transcriptome-wide association study of asthma reveals genetically driven mucus pathobiology.
  Nature communications 2022 Sajuthi SP, Everman JL, Jackson ND, Saef B, Rios CL, Moore CM, Mak ACY, Eng C, Fairbanks-Mahnke A, Salazar S, Elhawary J, Huntsman S, Medina V, Nickerson DA, Germer S, Zody MC, Abecasis G, Kang HM, …
• Genetic Ancestry to Improve Precision of Race/Ethnicity-based Lung Function Equations in Children.
  American journal of respiratory and critical care medicine 2022 Witonsky J, Elhawary JR, Eng C, Rodríguez-Santana JR, Borrell LN, Burchard EG
• Epigenome-wide association study of lung function in Latino children and youth with asthma.
  Clinical epigenetics 2022 Herrera-Luis E, Li A, Mak ACY, Perez-Garcia J, Elhawary JR, Oh SS, Hu D, Eng C, Keys KL, Huntsman S, Beckman KB, Borrell LN, Rodriguez-Santana J, Burchard EG, Pino-Yanes M
• Race- and Ethnicity-Based Spirometry Reference Equations: Are They Accurate for Genetically Admixed Children?
  Chest 2022 Witonsky J, Elhawary JR, Eng C, Rodríguez-Santana JR, Borrell LN, Burchard EG
• Multiomics analysis identifies BIRC3 as a novel glucocorticoid response-associated gene.
  The Journal of allergy and clinical immunology 2021 Kan M, Diwadkar AR, Shuai H, Joo J, Wang AL, Ong MS, Sordillo JE, Iribarren C, Lu MX, Hernandez-Pacheco N, Perez-Garcia J, Gorenjak M, Potocnik U, Burchard EG, Pino-Yanes M, Wu AC, Himes BE
• Disentangling the impact of alcohol use and hepatitis C on insulin action in Latino individuals.
  Alcoholism, clinical and experimental research 2021 Kim RG, Kramer-Feldman J, Bacchetti P, Grimes B, Burchard E, Eng C, Hu D, Hellerstein M, Khalili M
• Pharmacogenetic studies of long-acting beta agonist and inhaled corticosteroid responsiveness in randomised controlled trials of individuals of African descent with asthma.
  The Lancet. Child & adolescent health 2021 Ortega VE, Daya M, Szefler SJ, Bleecker ER, Chinchilli VM, Phipatanakul W, Mauger D, Martinez FD, Herrera-Luis E, Pino-Yanes M, Hawkins GA, Ampleford EJ, Kunselman SJ, Cox C, Bacharier LB, Cabana MD, …
• Role of Sex on the Genetic Susceptibility to Childhood Asthma in Latinos and African Americans.
  Journal of personalized medicine 2021 Espuela-Ortiz A, Herrera-Luis E, Lorenzo-Díaz F, Hu D, Eng C, Villar J, Rodriguez-Santana JR, Burchard EG, Pino-Yanes M
• Lymph node-resident dendritic cells drive TH2 cell development involving MARCH1.
  Science immunology 2021 Castellanos CA, Ren X, Gonzalez SL, Li HK, Schroeder AW, Liang HE, Laidlaw BJ, Hu D, Mak ACY, Eng C, Rodríguez-Santana JR, LeNoir M, Yan Q, Celedón JC, Burchard EG, Zamvil SS, Ishido S, Locksley RM, …
• LTA4H rs2660845 association with montelukast response in early and late-onset asthma.
  PloS one 2021 Maroteau C, Espuela-Ortiz A, Herrera-Luis E, Srinivasan S, Carr F, Tavendale R, Wilson K, Hernandez-Pacheco N, Chalmers JD, Turner S, Mukhopadhyay S, Maitland-van der Zee AH, Burchard EG, Pino-Yanes M…
• Paths and timings of the peopling of Polynesia inferred from genomic networks.
  Nature 2021 Ioannidis AG, Blanco-Portillo J, Sandoval K, Hagelberg E, Barberena-Jonas C, Hill AVS, Rodríguez-Rodríguez JE, Fox K, Robson K, Haoa-Cardinali S, Quinto-Cortés CD, Miquel-Poblete JF, Auckland K, Parks…
• Racial/ethnic differences in eligibility for asthma biologics among pediatric populations.
  The Journal of allergy and clinical immunology 2021 Wohlford EM, Huang PF, Elhawary JR, Millette LA, Contreras MG, Witonsky J, Holweg CTJ, Oh SS, Lee C, Merenda C, Rabin RL, Araojo R, Mak ACY, Eng CS, Hu D, Huntsman S, LeNoir MA, Rodríguez-Santana JR, …
• Population sequencing data reveal a compendium of mutational processes in the human germ line.
  Science (New York, N.Y.) 2021 Seplyarskiy VB, Soldatov RA, Koch E, McGinty RJ, Goldmann JM, Hernandez RD, Barnes K, Correa A, Burchard EG, Ellinor PT, McGarvey ST, Mitchell BD, Vasan RS, Redline S, Silverman E, Weiss ST, Arnett DK…
• Identification of ROBO2 as a Potential Locus Associated with Inhaled Corticosteroid Response in Childhood Asthma.
  Journal of personalized medicine 2021 Hernandez-Pacheco N, Gorenjak M, Li J, Repnik K, Vijverberg SJ, Berce V, Jorgensen A, Karimi L, Schieck M, Samedy-Bates LA, Tavendale R, Villar J, Mukhopadhyay S, Pirmohamed M, Verhamme KMC, Kabesch M…
• ADRB2 haplotypes and asthma exacerbations in children and young adults: An individual participant data meta-analysis.
  Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2021 Karimi L, Vijverberg SJ, Engelkes M, Hernandez-Pacheco N, Farzan N, Soares P, Pino-Yanes M, Jorgensen AL, Eng C, Mukhopadhyay S, Schieck M, Kabesch M, Burchard EG, Chew FT, Sio YY, Potocnik U, …
• Office of Management and Budget Racial/Ethnic Categories in Mortality Research: A Framework for Including the Voices of Racialized Communities.
  American journal of public health 2021 Hayes-Bautista DE, Bryant M, Yudell M, Hayes-Bautista TM, Partlow K, Popejoy AB, Burchard E, Hsu P
• Robust, flexible, and scalable tests for Hardy-Weinberg equilibrium across diverse ancestries.
  Genetics 2021 Kwong AM, Blackwell TW, LeFaive J, de Andrade M, Barnard J, Barnes KC, Blangero J, Boerwinkle E, Burchard EG, Cade BE, Chasman DI, Chen H, Conomos MP, Cupples LA, Ellinor PT, Eng C, Gao Y, Guo X, …
• Genome-wide association study of asthma exacerbations despite inhaled corticosteroid use.
  The European respiratory journal 2021 Hernandez-Pacheco N, Vijverberg SJ, Herrera-Luis E, Li J, Sio YY, Granell R, Corrales A, Maroteau C, Lethem R, Perez-Garcia J, Farzan N, Repnik K, Gorenjak M, Soares P, Karimi L, Schieck M, Pérez-…
• A genome-wide association study of severe asthma exacerbations in Latino children and adolescents.
  The European respiratory journal 2021 Yan Q, Forno E, Herrera-Luis E, Pino-Yanes M, Qi C, Rios R, Han YY, Kim S, Oh S, Acosta-Pérez E, Zhang R, Hu D, Eng C, Huntsman S, Avila L, Boutaoui N, Cloutier MM, Soto-Quiros ME, Xu CJ, Weiss ST, …
• Genome-wide association studies of exacerbations in children using long-acting beta2-agonists.
  Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology 2021 Slob EMA, Richards LB, Vijverberg SJH, Longo C, Koppelman GH, Pijnenburg MWH, Bel EHD, Neerincx AH, Herrera Luis E, Perez-Garcia J, Tim Chew F, Yie Sio Y, Andiappan AK, Turner SW, Mukhopadhyay S, …
• Author Correction: Inherited causes of clonal haematopoiesis in 97,691 whole genomes.
  Nature 2021 Bick AG, Weinstock JS, Nandakumar SK, Fulco CP, Bao EL, Zekavat SM, Szeto MD, Liao X, Leventhal MJ, Nasser J, Chang K, Laurie C, Burugula BB, Gibson CJ, Niroula A, Lin AE, Taub MA, Aguet F, Ardlie K, …
• Mapping the 17q12-21.1 Locus for Variants Associated with Early-Onset Asthma in African Americans.
  American journal of respiratory and critical care medicine 2021 Gui H, Levin AM, Hu D, Sleiman P, Xiao S, Mak ACY, Yang M, Barczak AJ, Huntsman S, Eng C, Hochstadt S, Zhang E, Whitehouse K, Simons S, Cabral W, Takriti S, Abecasis G, Blackwell TW, Kang HM, …
• Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program.
  Nature 2021 Taliun D, Harris DN, Kessler MD, Carlson J, Szpiech ZA, Torres R, Taliun SAG, Corvelo A, Gogarten SM, Kang HM, Pitsillides AN, LeFaive J, Lee SB, Tian X, Browning BL, Das S, Emde AK, Clarke WE, Loesch…
• Native American Ancestry and Air Pollution Interact to Impact Bronchodilator Response in Puerto Rican Children with Asthma.
  Ethnicity & disease 2021 Contreras MG, Keys K, Magaña J, Goddard PC, Risse-Adams O, Zeiger AM, Mak ACY, Samedy-Bates LA, Neophytou AM, Lee E, Thakur N, Elhawary JR, Hu D, Huntsman S, Eng C, Hu T, Burchard EG, White MJ
• Race and Genetic Ancestry in Medicine - A Time for Reckoning with Racism.
  The New England journal of medicine 2021 Borrell LN, Elhawary JR, Fuentes-Afflick E, Witonsky J, Bhakta N, Wu AHB, Bibbins-Domingo K, Rodríguez-Santana JR, Lenoir MA, Gavin JR, Kittles RA, Zaitlen NA, Wilkes DS, Powe NR, Ziv E, Burchard EG
• NLRP1 variant M1184V decreases inflammasome activation in the context of DPP9 inhibition and asthma severity.
  The Journal of allergy and clinical immunology 2020 Moecking J, Laohamonthonkul P, Chalker K, White MJ, Harapas CR, Yu CH, Davidson S, Hrovat-Schaale K, Hu D, Eng C, Huntsman S, Calleja DJ, Horvat JC, Hansbro PM, O'Donoghue RJJ, Ting JP, Burchard EG, …
• Asthma and its relationship to mitochondrial copy number: Results from the Asthma Translational Genomics Collaborative (ATGC) of the Trans-Omics for Precision Medicine (TOPMed) program.
  PloS one 2020 Cocco MP, White E, Xiao S, Hu D, Mak A, Sleiman P, Yang M, Bobbitt KR, Gui H, Levin AM, Hochstadt S, Whitehouse K, Rynkowski D, Barczak AJ, Abecasis G, Blackwell TW, Kang HM, Nickerson DA, Germer S, …
• Inherited causes of clonal haematopoiesis in 97,691 whole genomes.
  Nature 2020 Bick AG, Weinstock JS, Nandakumar SK, Fulco CP, Bao EL, Zekavat SM, Szeto MD, Liao X, Leventhal MJ, Nasser J, Chang K, Laurie C, Burugula BB, Gibson CJ, Lin AE, Taub MA, Aguet F, Ardlie K, Mitchell BD…
• Type 2 and interferon inflammation regulate SARS-CoV-2 entry factor expression in the airway epithelium.
  Nature communications 2020 Sajuthi SP, DeFord P, Li Y, Jackson ND, Montgomery MT, Everman JL, Rios CL, Pruesse E, Nolin JD, Plender EG, Wechsler ME, Mak ACY, Eng C, Salazar S, Medina V, Wohlford EM, Huntsman S, Nickerson DA, …
• A deoxyribonuclease 1-like 3 genetic variant associates with asthma exacerbations.
  The Journal of allergy and clinical immunology 2020 Herrera-Luis E, Lorenzo-Diaz F, Samedy-Bates LA, Eng C, Villar J, Rodriguez-Santana JR, Burchard EG, Pino-Yanes M
• Whole-Genome Sequencing Identifies Novel Functional Loci Associated with Lung Function in Puerto Rican Youth.
  American journal of respiratory and critical care medicine 2020 Lee EY, Mak ACY, Hu D, Sajuthi S, White MJ, Keys KL, Eckalbar W, Bonser L, Huntsman S, Urbanek C, Eng C, Jain D, Abecasis G, Kang HM, Germer S, Zody MC, Nickerson DA, Erle D, Ziv E, Rodriguez-Santana …
• Integrative genomic analysis in African American children with asthma finds three novel loci associated with lung function.
  Genetic epidemiology 2020 Goddard PC, Keys KL, Mak ACY, Lee EY, Liu AK, Samedy-Bates LA, Risse-Adams O, Contreras MG, Elhawary JR, Hu D, Huntsman S, Oh SS, Salazar S, Eng C, Himes BE, White MJ, Burchard EG
• Combined analysis of transcriptomic and genetic data for the identification of loci involved in glucocorticosteroid response in asthma.
  Allergy 2020 Hernandez-Pacheco N, Gorenjak M, Jurgec S, Corrales A, Jorgensen A, Karimi L, Vijverberg SJ, Berce V, Schieck M, Acosta-Herrera M, Kerick M, Samedy-Bates LA, Tavendale R, Villar J, Mukhopadhyay S, …
• Genome-wide association study reveals a novel locus for asthma with severe exacerbations in diverse populations.
  Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology 2020 Herrera-Luis E, Espuela-Ortiz A, Lorenzo-Diaz F, Keys KL, Mak ACY, Eng C, Huntsman S, Villar J, Rodriguez-Santana JR, Burchard EG, Pino-Yanes M
• A genome-wide association study of asthma hospitalizations in adults.
  The Journal of allergy and clinical immunology 2020 Yan Q, Forno E, Herrera-Luis E, Pino-Yanes M, Yang G, Oh S, Acosta-Pérez E, Hu D, Eng C, Huntsman S, Rodriguez-Santana JR, Cloutier MM, Canino G, Burchard EG, Chen W, Celedón JC
• A genome-wide study of DNA methylation in white blood cells and asthma in Latino children and youth.
  Epigenetics 2020 Jiang Y, Forno E, Han YY, Xu Z, Hu D, Boutaoui N, Eng C, Acosta-Pérez E, Huntsman S, Colón-Semidey A, Keys KL, Rodríguez-Santana JR, Alvarez M, Pino-Yanes M, Canino G, Chen W, Burchard EG, Celedón JC
• On the cross-population generalizability of gene expression prediction models.
  PLoS genetics 2020 Keys KL, Mak ACY, White MJ, Eckalbar WL, Dahl AW, Mefford J, Mikhaylova AV, Contreras MG, Elhawary JR, Eng C, Hu D, Huntsman S, Oh SS, Salazar S, Lenoir MA, Ye JC, Thornton TA, Zaitlen N, Burchard EG,…
• Genome-Wide Analysis Reveals Mucociliary Remodeling of the Nasal Airway Epithelium Induced by Urban PM2.5.
  American journal of respiratory cell and molecular biology 2020 Montgomery MT, Sajuthi SP, Cho SH, Everman JL, Rios CL, Goldfarbmuren KC, Jackson ND, Saef B, Cromie M, Eng C, Medina V, Elhawary JR, Oh SS, Rodriguez-Santana J, Vladar EK, Burchard EG, Seibold MA
• Native American gene flow into Polynesia predating Easter Island settlement.
  Nature 2020 Ioannidis AG, Blanco-Portillo J, Sandoval K, Hagelberg E, Miquel-Poblete JF, Moreno-Mayar JV, Rodríguez-Rodríguez JE, Quinto-Cortés CD, Auckland K, Parks T, Robson K, Hill AVS, Avila-Arcos MC, Sockell…
• Single-Cell and Population Transcriptomics Reveal Pan-epithelial Remodeling in Type 2-High Asthma.
  Cell reports 2020 Jackson ND, Everman JL, Chioccioli M, Feriani L, Goldfarbmuren KC, Sajuthi SP, Rios CL, Powell R, Armstrong M, Gomez J, Michel C, Eng C, Oh SS, Rodriguez-Santana J, Cicuta P, Reisdorph N, Burchard EG,…
• An epistatic interaction between pre-natal smoke exposure and socioeconomic status has a significant impact on bronchodilator drug response in African American youth with asthma.
  BioData mining 2020 Magaña J, Contreras MG, Keys KL, Risse-Adams O, Goddard PC, Zeiger AM, Mak ACY, Elhawary JR, Samedy-Bates LA, Lee E, Thakur N, Hu D, Eng C, Salazar S, Huntsman S, Hu T, Burchard EG, White MJ
• Sequencing and imputation in GWAS: Cost-effective strategies to increase power and genomic coverage across diverse populations.
  Genetic epidemiology 2020 Quick C, Anugu P, Musani S, Weiss ST, Burchard EG, White MJ, Keys KL, Cucca F, Sidore C, Boehnke M, Fuchsberger C
• Differential asthma odds following respiratory infection in children from three minority populations.
  PloS one 2020 Wohlford EM, Borrell LN, Elhawary JR, Plotkin B, Oh SS, Nuckton TJ, Eng C, Salazar S, LeNoir MA, Meade K, Farber HJ, Serebrisky D, Brigino-Buenaventura E, Rodriguez-Cintron W, Kumar R, Thyne S, …
• Lung Function in African American Children with Asthma Is Associated with Novel Regulatory Variants of the KIT Ligand KITLG/SCF and Gene-By-Air-Pollution Interaction.
  Genetics 2020 Mak ACY, Sajuthi S, Joo J, Xiao S, Sleiman PM, White MJ, Lee EY, Saef B, Hu D, Gui H, Keys KL, Lurmann F, Jain D, Abecasis G, Kang HM, Nickerson DA, Germer S, Zody MC, Winterkorn L, Reeves C, Huntsman…
• Development of a small panel of SNPs to infer ancestry in Chileans that distinguishes Aymara and Mapuche components.
  Biological research 2020 Verdugo RA, Di Genova A, Herrera L, Moraga M, Acuña M, Berríos S, Llop E, Valenzuela CY, Bustamante ML, Digman D, Symon A, Asenjo S, López P, Blanco A, Suazo J, Barozet E, Caba F, Villalón M, Alvarado…
• Type 2 and interferon inflammation strongly regulate SARS-CoV-2 related gene expression in the airway epithelium.
  bioRxiv : the preprint server for biology 2020 Sajuthi SP, DeFord P, Jackson ND, Montgomery MT, Everman JL, Rios CL, Pruesse E, Nolin JD, Plender EG, Wechsler ME, Mak AC, Eng C, Salazar S, Medina V, Wohlford EM, Huntsman S, Nickerson DA, Germer S,…
• Outdoor Air Pollution and New-Onset Airway Disease. An Official American Thoracic Society Workshop Report.
  Annals of the American Thoracic Society 2020 Thurston GD, Balmes JR, Garcia E, Gilliland FD, Rice MB, Schikowski T, Van Winkle LS, Annesi-Maesano I, Burchard EG, Carlsten C, Harkema JR, Khreis H, Kleeberger SR, Kodavanti UP, London SJ, McConnell…
• Population History and Gene Divergence in Native Mexicans Inferred from 76 Human Exomes.
  Molecular biology and evolution 2020 Ávila-Arcos MC, McManus KF, Sandoval K, Rodríguez-Rodríguez JE, Villa-Islas V, Martin AR, Luisi P, Peñaloza-Espinosa RI, Eng C, Huntsman S, Burchard EG, Gignoux CR, Bustamante CD, Moreno-Estrada A
• Expression of SMARCD1 interacts with age in association with asthma control on inhaled corticosteroid therapy.
  Respiratory research 2020 McGeachie MJ, Sordillo JE, Dahlin A, Wang AL, Lutz SM, Tantisira KG, Panganiban R, Lu Q, Sajuthi S, Urbanek C, Kelly R, Saef B, Eng C, Oh SS, Kho AT, Croteau-Chonka DC, Weiss ST, Raby BA, Mak ACY, …
• IL1RL1 gene variations are associated with asthma exacerbations in children and adolescents using inhaled corticosteroids.
  Allergy 2019 Dijk FN, Vijverberg SJ, Hernandez-Pacheco N, Repnik K, Karimi L, Mitratza M, Farzan N, Nawijn MC, Burchard EG, Engelkes M, Verhamme KM, Potocnik U, Pino-Yanes M, Postma DS, Maitland-van der Zee AH, …
• Atopic dermatitis, race, and genetics.
  The Journal of allergy and clinical immunology 2019 Kumar R, Seibold MA, Burchard EG
• Identification of CFTR variants in Latino patients with cystic fibrosis from the Dominican Republic and Puerto Rico.
  Pediatric pulmonology 2019 Zeiger AM, McGarry ME, Mak ACY, Medina V, Salazar S, Eng C, Liu AK, Oh SS, Nuckton TJ, Jain D, Blackwell TW, Kang HM, Abecasis G, Oñate LC, Seibold MA, Burchard EG, Rodriguez-Santana J
• Whole Genome Sequencing Identifies CRISPLD2 as a Lung Function Gene in Children With Asthma.
  Chest 2019 Kachroo P, Hecker J, Chawes BL, Ahluwalia TS, Cho MH, Qiao D, Kelly RS, Chu SH, Virkud YV, Huang M, Barnes KC, Burchard EG, Eng C, Hu D, Celedón JC, Daya M, Levin AM, Gui H, Williams LK, Forno E, Mak …
• Ancestry-Dependent Enrichment of Deleterious Homozygotes in Runs of Homozygosity.
  American journal of human genetics 2019 Szpiech ZA, Mak ACY, White MJ, Hu D, Eng C, Burchard EG, Hernandez RD
• Bacterial salivary microbiome associates with asthma among african american children and young adults.
  Pediatric pulmonology 2019 Espuela-Ortiz A, Lorenzo-Diaz F, Baez-Ortega A, Eng C, Hernandez-Pacheco N, Oh SS, Lenoir M, Burchard EG, Flores C, Pino-Yanes M
• Author Correction: Association study in African-admixed populations across the Americas recapitulates asthma risk loci in non-African populations.
  Nature communications 2019 Daya M, Rafaels N, Brunetti TM, Chavan S, Levin AM, Shetty A, Gignoux CR, Boorgula MP, Wojcik G, Campbell M, Vergara C, Torgerson DG, Ortega VE, Doumatey A, Johnston HR, Acevedo N, Araujo MI, Avila PC…
• The genetic diversity of multiple sclerosis risk among Hispanic and African American populations living in the United States.
  Multiple sclerosis (Houndmills, Basingstoke, England) 2019 Beecham AH, Amezcua L, Chinea A, Manrique CP, Rubi C, Isobe N, Lund BT, Santaniello A, Beecham GW, Burchard EG, Comabella M, Patsopoulos N, Fitzgerald K, Calabresi PA, De Jager P, Conti DV, Delgado SR…
• Racial/Ethnic-Specific Differences in the Effects of Inhaled Corticosteroid Use on Bronchodilator Response in Patients With Asthma.
  Clinical pharmacology and therapeutics 2019 Samedy-Bates LA, Oh SS, Nuckton TJ, Elhawary JR, White M, Elliot T, Zeiger AM, Eng C, Salazar S, LeNoir MA, Meade K, Farber HJ, Serebrisky D, Brigino-Buenaventura E, Rodriguez-Cintron W, Bibbins-…
• Meta-analysis of GWA studies provides new insights on the genetic architecture of skin pigmentation in recently admixed populations.
  BMC genetics 2019 Lona-Durazo F, Hernandez-Pacheco N, Fan S, Zhang T, Choi J, Kovacs MA, Loftus SK, Le P, Edwards M, Fortes-Lima CA, Eng C, Huntsman S, Hu D, Gómez-Cabezas EJ, Marín-Padrón LC, Grauholm J, Mors O, …
• Ambient air pollution, asthma drug response, and telomere length in African American youth.
  The Journal of allergy and clinical immunology 2019 Lee EY, Oh SS, White MJ, Eng CS, Elhawary JR, Borrell LN, Nuckton TJ, Zeiger AM, Keys KL, Mak ACY, Hu D, Huntsman S, Contreras MG, Samedy LA, Goddard PC, Salazar SL, Brigino-Buenaventura EN, Davis A, …
• In utero tobacco smoke exposure, DNA methylation, and asthma in Latino children.
  Environmental epidemiology (Philadelphia, Pa.) 2019 Neophytou AM, Oh SS, Hu D, Huntsman S, Eng C, Rodríguez-Santana JR, Kumar R, Balmes JR, Eisen EA, Burchard EG
• Functional genomics of CDHR3 confirms its role in HRV-C infection and childhood asthma exacerbations.
  The Journal of allergy and clinical immunology 2019 Everman JL, Sajuthi S, Saef B, Rios C, Stoner AM, Numata M, Hu D, Eng C, Oh S, Rodriguez-Santana J, Vladar EK, Voelker DR, Burchard EG, Seibold MA
• Association study in African-admixed populations across the Americas recapitulates asthma risk loci in non-African populations.
  Nature communications 2019 Daya M, Rafaels N, Brunetti TM, Chavan S, Levin AM, Shetty A, Gignoux CR, Boorgula MP, Wojcik G, Campbell M, Vergara C, Torgerson DG, Ortega VE, Doumatey A, Johnston HR, Acevedo N, Araujo MI, Avila PC…
• Genome-wide association study of inhaled corticosteroid response in admixed children with asthma.
  Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2019 Hernandez-Pacheco N, Farzan N, Francis B, Karimi L, Repnik K, Vijverberg SJ, Soares P, Schieck M, Gorenjak M, Forno E, Eng C, Oh SS, Pérez-Méndez L, Berce V, Tavendale R, Samedy LA, Hunstman S, Hu D, …
• Author Correction: Assembly of a pan-genome from deep sequencing of 910 humans of African descent.
  Nature genetics 2019 Sherman RM, Forman J, Antonescu V, Puiu D, Daya M, Rafaels N, Boorgula MP, Chavan S, Vergara C, Ortega VE, Levin AM, Eng C, Yazdanbakhsh M, Wilson JG, Marrugo J, Lange LA, Williams LK, Watson H, Ware …
• Acculturation is associated with asthma burden and pulmonary function in Latino youth: The GALA II study.
  The Journal of allergy and clinical immunology 2019 Thakur N, Borrell LN, Ye M, Oh SS, Eng C, Meade K, Avila PC, Farber HJ, Serebrisky D, Brigino-Buenaventura E, Rodriguez-Cintron W, Kumar R, Bibbins-Domingo K, Thyne S, Sen S, Rodriguez-Santana JR, …
• Identification of novel common breast cancer risk variants at the 6q25 locus among Latinas.
  Breast cancer research : BCR 2019 Hoffman J, Fejerman L, Hu D, Huntsman S, Li M, John EM, Torres-Mejia G, Kushi L, Ding YC, Weitzel J, Neuhausen SL, Lott P, COLUMBUS Consortium, Echeverry M, Carvajal-Carmona L, Burchard E, Eng C, Long…
• Epigenome-wide meta-analysis of DNA methylation and childhood asthma.
  The Journal of allergy and clinical immunology 2018 Reese SE, Xu CJ, den Dekker HT, Lee MK, Sikdar S, Ruiz-Arenas C, Merid SK, Rezwan FI, Page CM, Ullemar V, Melton PE, Oh SS, Yang IV, Burrows K, Söderhäll C, Jima DD, Gao L, Arathimos R, Küpers LK, …
• Current Status and Future Opportunities in Lung Precision Medicine Research with a Focus on Biomarkers. An American Thoracic Society/National Heart, Lung, and Blood Institute Research Statement.
  American journal of respiratory and critical care medicine 2018 Wu AC, Kiley JP, Noel PJ, Amur S, Burchard EG, Clancy JP, Galanter J, Inada M, Jones TK, Kropski JA, Loyd JE, Nogee LM, Raby BA, Rogers AJ, Schwartz DA, Sin DD, Spira A, Weiss ST, Young LR, Himes BE
• Association Between Titin Loss-of-Function Variants and Early-Onset Atrial Fibrillation.
  JAMA 2018 Choi SH, Weng LC, Roselli C, Lin H, Haggerty CM, Shoemaker MB, Barnard J, Arking DE, Chasman DI, Albert CM, Chaffin M, Tucker NR, Smith JD, Gupta N, Gabriel S, Margolin L, Shea MA, Shaffer CM, Yoneda …
• Novel susceptibility variants at the ERG locus for childhood acute lymphoblastic leukemia in Hispanics.
  Blood 2018 Qian M, Xu H, Perez-Andreu V, Roberts KG, Zhang H, Yang W, Zhang S, Zhao X, Smith C, Devidas M, Gastier-Foster JM, Raetz E, Larsen E, Burchard EG, Winick N, Bowman WP, Martin PL, Borowitz M, Wood B, …
• Genetic loci determining total immunoglobulin E levels from birth through adulthood.
  Allergy 2018 Yao TC, Chung RH, Lin CY, Tsai PC, Chang WC, Yeh KW, Tsai MH, Liao SL, Hua MC, Lai SH, Chen LC, Chang SW, Yu YW, Hsu JY, Chang SC, Cheng WC, Hu D, Hong X, Burchard EG, Wang X, Tzeng JY, Tsai HJ, Huang…
• Assembly of a pan-genome from deep sequencing of 910 humans of African descent.
  Nature genetics 2018 Sherman RM, Forman J, Antonescu V, Puiu D, Daya M, Rafaels N, Boorgula MP, Chavan S, Vergara C, Ortega VE, Levin AM, Eng C, Yazdanbakhsh M, Wilson JG, Marrugo J, Lange LA, Williams LK, Watson H, Ware …
• Novel locus for atopic dermatitis in African Americans and replication in European Americans.
  The Journal of allergy and clinical immunology 2018 Almoguera B, Vazquez L, Mentch F, March ME, Connolly JJ, Peissig PL, Linneman JG, Plaza-Serón MDC, Pino-Yanes M, Burchard EG, Brilliant M, Sleiman P, Hakonarson H
• Integrative approach identifies corticosteroid response variant in diverse populations with asthma.
  The Journal of allergy and clinical immunology 2018 Levin AM, Gui H, Hernandez-Pacheco N, Yang M, Xiao S, Yang JJ, Hochstadt S, Barczak AJ, Eckalbar WL, Rynkowski D, Samedy LA, Kwok PY, Pino-Yanes M, Erle DJ, Lanfear DE, Burchard EG, Williams LK
• A genome-wide association and admixture mapping study of bronchodilator drug response in African Americans with asthma.
  The pharmacogenomics journal 2018 Spear ML, Hu D, Pino-Yanes M, Huntsman S, Eng C, Levin AM, Ortega VE, White MJ, McGarry ME, Thakur N, Galanter J, Mak ACY, Oh SS, Ampleford E, Peters SP, Davis A, Kumar R, Farber HJ, Meade K, Avila PC…
• An admixture mapping meta-analysis implicates genetic variation at 18q21 with asthma susceptibility in Latinos.
  The Journal of allergy and clinical immunology 2018 Gignoux CR, Torgerson DG, Pino-Yanes M, Uricchio LH, Galanter J, Roth LA, Eng C, Hu D, Nguyen EA, Huntsman S, Mathias RA, Kumar R, Rodriguez-Santana J, Thakur N, Oh SS, McGarry M, Moreno-Estrada A, …
• Genetic Determinants of Telomere Length in African American Youth.
  Scientific reports 2018 Zeiger AM, White MJ, Eng C, Oh SS, Witonsky J, Goddard PC, Contreras MG, Elhawary JR, Hu D, Mak ACY, Lee EY, Keys KL, Samedy LA, Risse-Adams O, Magaña J, Huntsman S, Salazar S, Davis A, Meade K, …
• Author Correction: Genome-wide association and HLA fine-mapping studies identify risk loci and genetic pathways underlying allergic rhinitis.
  Nature genetics 2018 Waage J, Standl M, Curtin JA, Jessen LE, Thorsen J, Tian C, Schoettler N, 23andMe Research Team, AAGC collaborators, Flores C, Abdellaoui A, Ahluwalia TS, Alves AC, Amaral AFS, Antó JM, Arnold A, …
• Ancestry and genetic associations with bronchopulmonary dysplasia in preterm infants.
  American journal of physiology. Lung cellular and molecular physiology 2018 Torgerson DG, Ballard PL, Keller RL, Oh SS, Huntsman S, Hu D, Eng C, Burchard EG, Ballard RA, TOLSURF Study Group
• Multiethnic meta-analysis identifies ancestry-specific and cross-ancestry loci for pulmonary function.
  Nature communications 2018 Wyss AB, Sofer T, Lee MK, Terzikhan N, Nguyen JN, Lahousse L, Latourelle JC, Smith AV, Bartz TM, Feitosa MF, Gao W, Ahluwalia TS, Tang W, Oldmeadow C, Duan Q, de Jong K, Wojczynski MK, Wang XQ, …
• Genome-wide association and HLA fine-mapping studies identify risk loci and genetic pathways underlying allergic rhinitis.
  Nature genetics 2018 Waage J, Standl M, Curtin JA, Jessen LE, Thorsen J, Tian C, Schoettler N, 23andMe Research Team, AAGC collaborators, Flores C, Abdellaoui A, Ahluwalia TS, Alves AC, Amaral AFS, Antó JM, Arnold A, …
• 17q21 variant increases the risk of exacerbations in asthmatic children despite inhaled corticosteroids use.
  Allergy 2018 Farzan N, Vijverberg SJ, Hernandez-Pacheco N, Bel EHD, Berce V, Bønnelykke K, Bisgaard H, Burchard EG, Canino G, Celedón JC, Chew FT, Chiang WC, Cloutier MM, Forno E, Francis B, Hawcutt DB, Herrera-…
• Whole-Genome Sequencing of Pharmacogenetic Drug Response in Racially Diverse Children with Asthma.
  American journal of respiratory and critical care medicine 2018 Mak ACY, White MJ, Eckalbar WL, Szpiech ZA, Oh SS, Pino-Yanes M, Hu D, Goddard P, Huntsman S, Galanter J, Wu AC, Himes BE, Germer S, Vogel JM, Bunting KL, Eng C, Salazar S, Keys KL, Liberto J, Nuckton…
• Secondhand smoke exposure and asthma outcomes among African-American and Latino children with asthma.
  Thorax 2018 Neophytou AM, Oh SS, White MJ, Mak ACY, Hu D, Huntsman S, Eng C, Serebrisky D, Borrell LN, Farber HJ, Meade K, Davis A, Avila PC, Thyne SM, Rodríguez-Cintrón W, Rodríguez-Santana JR, Kumar R, Brigino-…
• Optimized distributed systems achieve significant performance improvement on sorted merging of massive VCF files.
  GigaScience 2018 Sun X, Gao J, Jin P, Eng C, Burchard EG, Beaty TH, Ruczinski I, Mathias RA, Barnes K, Wang F, Qin ZS, CAAPA consortium
• Variants in genes coding for glutathione S-transferases and asthma outcomes in children.
  Pharmacogenomics 2018 Turner S, Francis B, Wani N, Vijverberg S, Pino-Yanes M, Mukhopadhyay S, Tavendale R, Palmer C, Burchard EG, Merid SK, Melén E, Maitland-van der Zee AH, The Pharmacogenomics In Childhood Asthma …
• Correction to: Dual RNA-seq reveals viral infections in asthmatic children without respiratory illness which are associated with changes in the airway transcriptome.
  Genome biology 2018 Wesolowska-Andersen A, Everman JL, Davidson R, Rios C, Herrin R, Eng C, Janssen WJ, Liu AH, Oh SS, Kumar R, Fingerlin TE, Rodriguez-Santana J, Burchard EG, Seibold MA
• Genomic insights into the origin and diversification of late maritime hunter-gatherers from the Chilean Patagonia.
  Proceedings of the National Academy of Sciences of the United States of America 2018 de la Fuente C, Ávila-Arcos MC, Galimany J, Carpenter ML, Homburger JR, Blanco A, Contreras P, Cruz Dávalos D, Reyes O, San Roman M, Moreno-Estrada A, Campos PF, Eng C, Huntsman S, Burchard EG, …
• Dysregulated invertebrate tropomyosin-dectin-1 interaction confers susceptibility to allergic diseases.
  Science immunology 2018 Gour N, Lajoie S, Smole U, White M, Hu D, Goddard P, Huntsman S, Eng C, Mak A, Oh S, Kim JH, Sharma A, Plante S, Salem IH, Resch Y, Xiao X, Yao N, Singh A, Vrtala S, Chakir J, Burchard EG, Lane AP, …
• ROP: dumpster diving in RNA-sequencing to find the source of 1 trillion reads across diverse adult human tissues.
  Genome biology 2018 Mangul S, Yang HT, Strauli N, Gruhl F, Porath HT, Hsieh K, Chen L, Daley T, Christenson S, Wesolowska-Andersen A, Spreafico R, Rios C, Eng C, Smith AD, Hernandez RD, Ophoff RA, Santana JR, Levanon EY,…
• Cohort Profile: Pregnancy And Childhood Epigenetics (PACE) Consortium.
  International journal of epidemiology 2018 Felix JF, Joubert BR, Baccarelli AA, Sharp GC, Almqvist C, Annesi-Maesano I, Arshad H, Baïz N, Bakermans-Kranenburg MJ, Bakulski KM, Binder EB, Bouchard L, Breton CV, Brunekreef B, Brunst KJ, Burchard…
• A genome-wide association study identifies only two ancestry specific variants associated with spontaneous preterm birth.
  Scientific reports 2018 Rappoport N, Toung J, Hadley D, Wong RJ, Fujioka K, Reuter J, Abbott CW, Oh S, Hu D, Eng C, Huntsman S, Bodian DL, Niederhuber JE, Hong X, Zhang G, Sikora-Wohfeld W, Gignoux CR, Wang H, Oehlert J, …
• Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks.
  Nature genetics 2017 Demenais F, Margaritte-Jeannin P, Barnes KC, Cookson WOC, Altmüller J, Ang W, Barr RG, Beaty TH, Becker AB, Beilby J, Bisgaard H, Bjornsdottir US, Bleecker E, Bønnelykke K, Boomsma DI, Bouzigon E, …
• An ancestry-based approach for detecting interactions.
  Genetic epidemiology 2017 Park DS, Eskin I, Kang EY, Gamazon ER, Eng C, Gignoux CR, Galanter JM, Burchard E, Ye CJ, Aschard H, Eskin E, Halperin E, Zaitlen N
• Pulmonary function disparities exist and persist in Hispanic patients with cystic fibrosis: A longitudinal analysis.
  Pediatric pulmonology 2017 McGarry ME, Neuhaus JM, Nielson DW, Burchard E, Ly NP
• Origins of Cancer Disparities in Young Adults: Logic Models to Guide Research.
  American journal of preventive medicine 2017 Hiatt RA, Handley MA, Ling PM, Burchard E, Thakur N, Bibbins-Domingo K
• Apolipoprotein E epsilon 4 (APOE-ε4) genotype is associated with decreased 6-month verbal memory performance after mild traumatic brain injury.
  Brain and behavior 2017 Yue JK, Robinson CK, Burke JF, Winkler EA, Deng H, Cnossen MC, Lingsma HF, Ferguson AR, McAllister TW, Rosand J, Burchard EG, Sorani MD, Sharma S, Nielson JL, Satris GG, Talbott JF, Tarapore PE, …
• American Thoracic Society/National Heart, Lung, and Blood Institute Asthma-Chronic Obstructive Pulmonary Disease Overlap Workshop Report.
  American journal of respiratory and critical care medicine 2017 Woodruff PG, van den Berge M, Boucher RC, Brightling C, Burchard EG, Christenson SA, Han MK, Holtzman MJ, Kraft M, Lynch DA, Martinez FD, Reddel HK, Sin DD, Washko GR, Wenzel SE, Punturieri A, Freemer…
• PAI-1 gain-of-function genotype, factors increasing PAI-1 levels, and airway obstruction: The GALA II Cohort.
  Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2017 Sherenian MG, Cho SH, Levin A, Min JY, Oh SS, Hu D, Galanter J, Sen S, Huntsman S, Eng C, Rodriguez-Santana JR, Serebrisky D, Avila PC, Kalhan R, Smith LJ, Borrell LN, Seibold MA, Keoki Williams L, …
• Rationale and design of the multiethnic Pharmacogenomics in Childhood Asthma consortium.
  Pharmacogenomics 2017 Farzan N, Vijverberg SJ, Andiappan AK, Arianto L, Berce V, Blanca-López N, Bisgaard H, Bønnelykke K, Burchard EG, Campo P, Canino G, Carleton B, Celedón JC, Chew FT, Chiang WC, Cloutier MM, Daley D, …
• Self-reported racial/ethnic discrimination and bronchodilator response in African American youth with asthma.
  PloS one 2017 Carlson S, Borrell LN, Eng C, Nguyen M, Thyne S, LeNoir MA, Burke-Harris N, Burchard EG, Thakur N
• A meta-analysis of genome-wide association studies of asthma in Puerto Ricans.
  The European respiratory journal 2017 Yan Q, Brehm J, Pino-Yanes M, Forno E, Lin J, Oh SS, Acosta-Perez E, Laurie CC, Cloutier MM, Raby BA, Stilp AM, Sofer T, Hu D, Huntsman S, Eng CS, Conomos MP, Rastogi D, Rice K, Canino G, Chen W, Barr…
• An American Thoracic Society/National Heart, Lung, and Blood Institute Workshop Report: Addressing Respiratory Health Equality in the United States.
  Annals of the American Thoracic Society 2017 Celedón JC, Burchard EG, Schraufnagel D, Castillo-Salgado C, Schenker M, Balmes J, Neptune E, Cummings KJ, Holguin F, Riekert KA, Wisnivesky JP, Garcia JGN, Roman J, Kittles R, Ortega VE, Redline S, …
• Identification of a novel locus associated with skin colour in African-admixed populations.
  Scientific reports 2017 Hernandez-Pacheco N, Flores C, Alonso S, Eng C, Mak AC, Hunstman S, Hu D, White MJ, Oh SS, Meade K, Farber HJ, Avila PC, Serebrisky D, Thyne SM, Brigino-Buenaventura E, Rodriguez-Cintron W, Sen S, …
• Correcting for cell-type heterogeneity in DNA methylation: a comprehensive evaluation.
  Nature methods 2017 Rahmani E, Zaitlen N, Baran Y, Eng C, Hu D, Galanter J, Oh S, Burchard EG, Eskin E, Zou J, Halperin E
• Suggestive association between variants in IL1RAPL and asthma symptoms in Latin American children.
  European journal of human genetics : EJHG 2017 Marques CR, Costa GN, da Silva TM, Oliveira P, Cruz AA, Alcantara-Neves NM, Fiaccone RL, Horta BL, Hartwig FP, Burchard EG, Pino-Yanes M, Rodrigues LC, Lima-Costa MF, Pereira AC, Gouveia MH, Sant Anna…
• Dual RNA-seq reveals viral infections in asthmatic children without respiratory illness which are associated with changes in the airway transcriptome.
  Genome biology 2017 Wesolowska-Andersen A, Everman JL, Davidson R, Rios C, Herrin R, Eng C, Janssen WJ, Liu AH, Oh SS, Kumar R, Fingerlin TE, Rodriguez-Santana J, Burchard EG, Seibold MA
• An epigenome-wide association study of total serum IgE in Hispanic children.
  The Journal of allergy and clinical immunology 2017 Chen W, Wang T, Pino-Yanes M, Forno E, Liang L, Yan Q, Hu D, Weeks DE, Baccarelli A, Acosta-Perez E, Eng C, Han YY, Boutaoui N, Laprise C, Davies GA, Hopkin JM, Moffatt MF, Cookson WOCM, Canino G, …
• Differential methylation between ethnic sub-groups reflects the effect of genetic ancestry and environmental exposures.
  eLife 2017 Galanter JM, Gignoux CR, Oh SS, Torgerson D, Pino-Yanes M, Thakur N, Eng C, Hu D, Huntsman S, Farber HJ, Avila PC, Brigino-Buenaventura E, LeNoir MA, Meade K, Serebrisky D, Rodríguez-Cintrón W, Kumar …
• Genome-wide methylation data mirror ancestry information.
  Epigenetics & chromatin 2017 Rahmani E, Shenhav L, Schweiger R, Yousefi P, Huen K, Eskenazi B, Eng C, Huntsman S, Hu D, Galanter J, Oh SS, Waldenberger M, Strauch K, Grallert H, Meitinger T, Gieger C, Holland N, Burchard EG, …
• Breastfeeding associated with higher lung function in African American youths with asthma.
  The Journal of asthma : official journal of the Association for the Care of Asthma 2016 Oh SS, Du R, Zeiger AM, McGarry ME, Hu D, Thakur N, Pino-Yanes M, Galanter JM, Eng C, Nishimura KK, Huntsman S, Farber HJ, Meade K, Avila P, Serebrisky D, Bibbins-Domingo K, Lenoir MA, Ford JG, …
• Perceived Discrimination Associated With Asthma and Related Outcomes in Minority Youth: The GALA II and SAGE II Studies.
  Chest 2016 Thakur N, Barcelo NE, Borrell LN, Singh S, Eng C, Davis A, Meade K, LeNoir MA, Avila PC, Farber HJ, Serebrisky D, Brigino-Buenaventura E, Rodriguez-Cintron W, Thyne S, Rodriguez-Santana JR, Sen S, …
• Towards Equity in Health: Researchers Take Stock.
  PLoS medicine 2016 PLOS Medicine Editors, Rid A, Johansson MA, Leung G, Valantine H, Burchard EG, Oh SS, Zimmerman C
• The Effects of Migration and Assortative Mating on Admixture Linkage Disequilibrium.
  Genetics 2016 Zaitlen N, Huntsman S, Hu D, Spear M, Eng C, Oh SS, White MJ, Mak A, Davis A, Meade K, Brigino-Buenaventura E, LeNoir MA, Bibbins-Domingo K, Burchard EG, Halperin E
• DRD2 C957T polymorphism is associated with improved 6-month verbal learning following traumatic brain injury.
  Neurogenetics 2016 Yue JK, Winkler EA, Rick JW, Burke JF, McAllister TW, Oh SS, Burchard EG, Hu D, Rosand J, Temkin NR, Korley FK, Sorani MD, Ferguson AR, Lingsma HF, Sharma S, Robinson CK, Yuh EL, Tarapore PE, Wang KK,…
• COMT Val158Met polymorphism is associated with post-traumatic stress disorder and functional outcome following mild traumatic brain injury.
  Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 2016 Winkler EA, Yue JK, Ferguson AR, Temkin NR, Stein MB, Barber J, Yuh EL, Sharma S, Satris GG, McAllister TW, Rosand J, Sorani MD, Lingsma HF, Tarapore PE, Burchard EG, Hu D, Eng C, Wang KK, Mukherjee P…
• A continuum of admixture in the Western Hemisphere revealed by the African Diaspora genome.
  Nature communications 2016 Mathias RA, Taub MA, Gignoux CR, Fu W, Musharoff S, O'Connor TD, Vergara C, Torgerson DG, Pino-Yanes M, Shringarpure SS, Huang L, Rafaels N, Boorgula MP, Johnston HR, Ortega VE, Levin AM, Song W, …
• Association of a PAI-1 Gene Polymorphism and Early Life Infections with Asthma Risk, Exacerbations, and Reduced Lung Function.
  PloS one 2016 Cho SH, Min JY, Kim DY, Oh SS, Torgerson DR, Pino-Yanes M, Hu D, Sen S, Huntsman S, Eng C, Farber HJ, Rodriguez-Cintron W, Rodriguez-Santana JR, Serebrisky D, Thyne SM, Borrell LN, Williams LK, DuPont…
• Predictive Properties of the Asthma Control Test and Its Component Questions for Severe Asthma Exacerbations.
  The journal of allergy and clinical immunology. In practice 2016 Cajigal S, Wells KE, Peterson EL, Ahmedani BK, Yang JJ, Kumar R, Burchard EG, Williams LK
• Maternal age and asthma in Latino populations.
  Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2016 Abid Z, Oh SS, Hu D, Sen S, Huntsman S, Eng C, Farber HJ, Rodriguez-Cintron W, Rodriguez-Santana JR, Serebrisky D, Avila PC, Thyne SM, Kim KA, Borrell LN, Williams LK, Seibold MA, Burchard EG, Kumar R
• Genetic Investigation Into the Differential Risk of Atrial Fibrillation Among Black and White Individuals.
  JAMA cardiology 2016 Roberts JD, Hu D, Heckbert SR, Alonso A, Dewland TA, Vittinghoff E, Liu Y, Psaty BM, Olgin JE, Magnani JW, Huntsman S, Burchard EG, Arking DE, Bibbins-Domingo K, Harris TB, Perez MV, Ziv E, Marcus GM
• What Ancestry Can Tell Us About the Genetic Origins of Inter-Ethnic Differences in Asthma Expression.
  Current allergy and asthma reports 2016 Hernandez-Pacheco N, Flores C, Oh SS, Burchard EG, Pino-Yanes M
• Early-life ozone exposure associated with asthma without sensitization in Latino children.
  The Journal of allergy and clinical immunology 2016 Nishimura KK, Iwanaga K, Oh SS, Pino-Yanes M, Eng C, Keswani A, Roth LA, Nguyen EA, Thyne SM, Farber HJ, Serebrisky D, Meade K, LeNoir MA, Rodriguez-Cintron W, Borrell LN, Bibbins-Domingo K, Lurmann F…
• Air Pollution and Lung Function in Minority Youth with Asthma in the GALA II (Genes-Environments and Admixture in Latino Americans) and SAGE II (Study of African Americans, Asthma, Genes, and Environments) Studies.
  American journal of respiratory and critical care medicine 2016 Neophytou AM, White MJ, Oh SS, Thakur N, Galanter JM, Nishimura KK, Pino-Yanes M, Torgerson DG, Gignoux CR, Eng C, Nguyen EA, Hu D, Mak AC, Kumar R, Seibold MA, Davis A, Farber HJ, Meade K, Avila PC, …
• Sensitization to mouse and cockroach allergens and asthma morbidity in urban minority youth: Genes-environments and Admixture in Latino American (GALA-II) and Study of African-Americans, Asthma, Genes, and Environments (SAGE-II).
  Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 2016 Fishbein AB, Lee TA, Cai M, Oh SS, Eng C, Hu D, Huntsman S, Farber HJ, Serebrisky D, Silverberg J, Williams LK, Seibold MA, Sen S, Borrell LN, Avila P, Rodriguez-Cintron W, Rodriguez-Santana JR, …
• Novel genetic risk factors for asthma in African American children: Precision Medicine and the SAGE II Study.
  Immunogenetics 2016 White MJ, Risse-Adams O, Goddard P, Contreras MG, Adams J, Hu D, Eng C, Oh SS, Davis A, Meade K, Brigino-Buenaventura E, LeNoir MA, Bibbins-Domingo K, Pino-Yanes M, Burchard EG
• The TAM family receptor tyrosine kinase TYRO3 is a negative regulator of type 2 immunity.
  Science (New York, N.Y.) 2016 Chan PY, Carrera Silva EA, De Kouchkovsky D, Joannas LD, Hao L, Hu D, Huntsman S, Eng C, Licona-Limón P, Weinstein JS, Herbert DR, Craft JE, Flavell RA, Repetto S, Correale J, Burchard EG, Torgerson …
• DNA Methylation in Newborns and Maternal Smoking in Pregnancy: Genome-wide Consortium Meta-analysis.
  American journal of human genetics 2016 Joubert BR, Felix JF, Yousefi P, Bakulski KM, Just AC, Breton C, Reese SE, Markunas CA, Richmond RC, Xu CJ, Küpers LK, Oh SS, Hoyo C, Gruzieva O, Söderhäll C, Salas LA, Baïz N, Zhang H, Lepeule J, …
• Sparse PCA corrects for cell type heterogeneity in epigenome-wide association studies.
  Nature methods 2016 Rahmani E, Zaitlen N, Baran Y, Eng C, Hu D, Galanter J, Oh S, Burchard EG, Eskin E, Zou J, Halperin E
• Assessing differences in inhaled corticosteroid response by self-reported race-ethnicity and genetic ancestry among asthmatic subjects.
  The Journal of allergy and clinical immunology 2016 Wells KE, Cajigal S, Peterson EL, Ahmedani BK, Kumar R, Lanfear DE, Burchard EG, Williams LK
• Racial Differences in Left Atrial Size: Results from the Coronary Artery Risk Development in Young Adults (CARDIA) Study.
  PloS one 2016 Dewland TA, Bibbins-Domingo K, Lin F, Vittinghoff E, Foster E, Ogunyankin KO, Lima JA, Jacobs DR, Hu D, Burchard EG, Marcus GM
• Making Precision Medicine Socially Precise. Take a Deep Breath.
  American journal of respiratory and critical care medicine 2016 Oh SS, White MJ, Gignoux CR, Burchard EG
• Childhood asthma exacerbations and the Arg16 β2-receptor polymorphism: A meta-analysis stratified by treatment.
  The Journal of allergy and clinical immunology 2016 Turner S, Francis B, Vijverberg S, Pino-Yanes M, Maitland-van der Zee AH, Basu K, Bignell L, Mukhopadhyay S, Tavendale R, Palmer C, Hawcutt D, Pirmohamed M, Burchard EG, Lipworth B, Pharmacogenomics …
• Diversity in Clinical and Biomedical Research: A Promise Yet to Be Fulfilled.
  PLoS medicine 2015 Oh SS, Galanter J, Thakur N, Pino-Yanes M, Barcelo NE, White MJ, de Bruin DM, Greenblatt RM, Bibbins-Domingo K, Wu AH, Borrell LN, Gunter C, Powe NR, Burchard EG
• A genome-wide association study of asthma symptoms in Latin American children.
  BMC genetics 2015 Costa GN, Dudbridge F, Fiaccone RL, da Silva TM, Conceição JS, Strina A, Figueiredo CA, Magalhães WC, Rodrigues MR, Gouveia MH, Kehdy FS, Horimoto AR, Horta B, Burchard EG, Pino-Yanes M, Del Rio …
• Powerful Tests for Multi-Marker Association Analysis Using Ensemble Learning.
  PloS one 2015 Padhukasahasram B, Reddy CK, Levin AM, Burchard EG, Williams LK
• COMT Val 158 Met polymorphism is associated with nonverbal cognition following mild traumatic brain injury.
  Neurogenetics 2015 Winkler EA, Yue JK, McAllister TW, Temkin NR, Oh SS, Burchard EG, Hu D, Ferguson AR, Lingsma HF, Burke JF, Sorani MD, Rosand J, Yuh EL, Barber J, Tarapore PE, Gardner RC, Sharma S, Satris GG, Eng C, …
• Pacifiplex: an ancestry-informative SNP panel centred on Australia and the Pacific region.
  Forensic science international. Genetics 2015 Santos C, Phillips C, Fondevila M, Daniel R, van Oorschot RAH, Burchard EG, Schanfield MS, Souto L, Uacyisrael J, Via M, Carracedo Á, Lareu MV
• Genetic and socioeconomic study of mate choice in Latinos reveals novel assortment patterns.
  Proceedings of the National Academy of Sciences of the United States of America 2015 Zou JY, Park DS, Burchard EG, Torgerson DG, Pino-Yanes M, Song YS, Sankararaman S, Halperin E, Zaitlen N
• Multi-ancestry genome-wide association study of 21,000 cases and 95,000 controls identifies new risk loci for atopic dermatitis.
  Nature genetics 2015 Paternoster L, Standl M, Waage J, Baurecht H, Hotze M, Strachan DP, Curtin JA, Bønnelykke K, Tian C, Takahashi A, Esparza-Gordillo J, Alves AC, Thyssen JP, den Dekker HT, Ferreira MA, Altmaier E, …
• A Genome-Wide Association Study of Post-bronchodilator Lung Function in Children with Asthma.
  American journal of respiratory and critical care medicine 2015 Brehm JM, Man Tse S, Croteau-Chonka DC, Forno E, Litonjua AA, Raby BA, Chen W, Yan Q, Boutaoui N, Acosta-Pérez E, Avila L, Weiss ST, Soto-Quiros M, Cloutier MM, Hu D, Pino-Yanes M, Wenzel SE, Spear ML…
• CRISPR-Cas9-mediated gene knockout in primary human airway epithelial cells reveals a proinflammatory role for MUC18.
  Gene therapy 2015 Chu HW, Rios C, Huang C, Wesolowska-Andersen A, Burchard EG, O'Connor BP, Fingerlin TE, Nichols D, Reynolds SD, Seibold MA
• Stress and Bronchodilator Response in Children with Asthma.
  American journal of respiratory and critical care medicine 2015 Brehm JM, Ramratnam SK, Tse SM, Croteau-Chonka DC, Pino-Yanes M, Rosas-Salazar C, Litonjua AA, Raby BA, Boutaoui N, Han YY, Chen W, Forno E, Marsland AL, Nugent NR, Eng C, Colón-Semidey A, Alvarez M, …
• Adapt-Mix: learning local genetic correlation structure improves summary statistics-based analyses.
  Bioinformatics (Oxford, England) 2015 Park DS, Brown B, Eng C, Huntsman S, Hu D, Torgerson DG, Burchard EG, Zaitlen N
• Inferring parental genomic ancestries using pooled semi-Markov processes.
  Bioinformatics (Oxford, England) 2015 Zou JY, Halperin E, Burchard E, Sankararaman S
• Obesity and bronchodilator response in black and Hispanic children and adolescents with asthma.
  Chest 2015 McGarry ME, Castellanos E, Thakur N, Oh SS, Eng C, Davis A, Meade K, LeNoir MA, Avila PC, Farber HJ, Serebrisky D, Brigino-Buenaventura E, Rodriguez-Cintron W, Kumar R, Bibbins-Domingo K, Thyne SM, …
• ST13 polymorphisms and their effect on exacerbations in steroid-treated asthmatic children and young adults.
  Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2015 Vijverberg SJ, Koster ES, Tavendale R, Leusink M, Koenderman L, Raaijmakers JA, Postma DS, Koppelman GH, Turner SW, Mukhopadhyay S, Tse SM, Tantisira KG, Hawcutt DB, Francis B, Pirmohamed M, Pino-…
• The Hawaii clopidogrel lawsuit: the possible effect on clinical laboratory testing.
  Personalized medicine 2015 Wu AH, White MJ, Oh S, Burchard E
• Fine mapping of the myosin light chain kinase (MYLK) gene replicates the association with asthma in populations of Spanish descent.
  The Journal of allergy and clinical immunology 2015 Acosta-Herrera M, Pino-Yanes M, Ma SF, Barreto-Luis A, Corrales A, Cumplido J, Pérez-Rodríguez E, Campo P, Eng C, García-Robaina JC, Quintela I, Villar J, Blanca M, Carracedo Á, Carrillo T, Garcia JG,…
• The landscape of genomic imprinting across diverse adult human tissues.
  Genome research 2015 Baran Y, Subramaniam M, Biton A, Tukiainen T, Tsang EK, Rivas MA, Pirinen M, Gutierrez-Arcelus M, Smith KS, Kukurba KR, Zhang R, Eng C, Torgerson DG, Urbanek C, GTEx Consortium, Li JB, Rodriguez-…
• PIGS: improved estimates of identity-by-descent probabilities by probabilistic IBD graph sampling.
  BMC bioinformatics 2015 Park DS, Baran Y, Hormozdiari F, Eng C, Torgerson DG, Burchard EG, Zaitlen N
• Moving toward true inclusion of racial/ethnic minorities in federally funded studies. A key step for achieving respiratory health equality in the United States.
  American journal of respiratory and critical care medicine 2015 Burchard EG, Oh SS, Foreman MG, Celedón JC
• Association of a common genetic variant within ANKK1 with six-month cognitive performance after traumatic brain injury.
  Neurogenetics 2015 Yue JK, Pronger AM, Ferguson AR, Temkin NR, Sharma S, Rosand J, Sorani MD, McAllister TW, Barber J, Winkler EA, Burchard EG, Hu D, Lingsma HF, Cooper SR, Puccio AM, Okonkwo DO, Diaz-Arrastia R, Manley…
• Ethnic-specific associations of rare and low-frequency DNA sequence variants with asthma.
  Nature communications 2015 Igartua C, Myers RA, Mathias RA, Pino-Yanes M, Eng C, Graves PE, Levin AM, Del-Rio-Navarro BE, Jackson DJ, Livne OE, Rafaels N, Edlund CK, Yang JJ, Huntsman S, Salam MT, Romieu I, Mourad R, Gern JE, …
• Genome-wide association study and admixture mapping reveal new loci associated with total IgE levels in Latinos.
  The Journal of allergy and clinical immunology 2014 Pino-Yanes M, Gignoux CR, Galanter JM, Levin AM, Campbell CD, Eng C, Huntsman S, Nishimura KK, Gourraud PA, Mohajeri K, O'Roak BJ, Hu D, Mathias RA, Nguyen EA, Roth LA, Padhukasahasram B, Moreno-…
• A genome-wide association study of susceptibility to acute lymphoblastic leukemia in adolescents and young adults.
  Blood 2014 Perez-Andreu V, Roberts KG, Xu H, Smith C, Zhang H, Yang W, Harvey RC, Payne-Turner D, Devidas M, Cheng IM, Carroll WL, Heerema NA, Carroll AJ, Raetz EA, Gastier-Foster JM, Marcucci G, Bloomfield CD, …
• Telomere length and the risk of atrial fibrillation: insights into the role of biological versus chronological aging.
  Circulation. Arrhythmia and electrophysiology 2014 Roberts JD, Dewland TA, Longoria J, Fitzpatrick AL, Ziv E, Hu D, Lin J, Glidden DV, Psaty BM, Burchard EG, Blackburn EH, Olgin JE, Heckbert SR, Marcus GM
• Genetic ancestry influences asthma susceptibility and lung function among Latinos.
  The Journal of allergy and clinical immunology 2014 Pino-Yanes M, Thakur N, Gignoux CR, Galanter JM, Roth LA, Eng C, Nishimura KK, Oh SS, Vora H, Huntsman S, Nguyen EA, Hu D, Drake KA, Conti DV, Moreno-Estrada A, Sandoval K, Winkler CA, Borrell LN, …
• Medical research: Missing patients.
  Nature 2014 Burchard EG
• Whole-genome sequencing of individuals from a founder population identifies candidate genes for asthma.
  PloS one 2014 Campbell CD, Mohajeri K, Malig M, Hormozdiari F, Nelson B, Du G, Patterson KM, Eng C, Torgerson DG, Hu D, Herman C, Chong JX, Ko A, O'Roak BJ, Krumm N, Vives L, Lee C, Roth LA, Rodriguez-Cintron W, …
• Integrated genome-wide association, coexpression network, and expression single nucleotide polymorphism analysis identifies novel pathway in allergic rhinitis.
  BMC medical genomics 2014 Bunyavanich S, Schadt EE, Himes BE, Lasky-Su J, Qiu W, Lazarus R, Ziniti JP, Cohain A, Linderman M, Torgerson DG, Eng CS, Pino-Yanes M, Padhukasahasram B, Yang JJ, Mathias RA, Beaty TH, Li X, Graves P…
• Nocturnal asthma and the importance of race/ethnicity and genetic ancestry.
  American journal of respiratory and critical care medicine 2014 Levin AM, Wang Y, Wells KE, Padhukasahasram B, Yang JJ, Burchard EG, Williams LK
• Genome-wide association analysis identifies six new loci associated with forced vital capacity.
  Nature genetics 2014 Loth DW, Soler Artigas M, Gharib SA, Wain LV, Franceschini N, Koch B, Pottinger TD, Smith AV, Duan Q, Oldmeadow C, Lee MK, Strachan DP, James AL, Huffman JE, Vitart V, Ramasamy A, Wareham NJ, Kaprio J…
• Human genetics. The genetics of Mexico recapitulates Native American substructure and affects biomedical traits.
  Science (New York, N.Y.) 2014 Moreno-Estrada A, Gignoux CR, Fernández-López JC, Zakharia F, Sikora M, Contreras AV, Acuña-Alonzo V, Sandoval K, Eng C, Romero-Hidalgo S, Ortiz-Tello P, Robles V, Kenny EE, Nuño-Arana I, Barquera-…
• Socioeconomic status and asthma control in African American youth in SAGE II.
  The Journal of asthma : official journal of the Association for the Care of Asthma 2014 Thakur N, Martin M, Castellanos E, Oh SS, Roth LA, Eng C, Brigino-Buenaventura E, Davis A, Meade K, LeNoir MA, Farber HJ, Thyne S, Sen S, Bibbins-Domingo K, Borrell LN, Burchard EG
• Genome-wide interaction studies reveal sex-specific asthma risk alleles.
  Human molecular genetics 2014 Myers RA, Scott NM, Gauderman WJ, Qiu W, Mathias RA, Romieu I, Levin AM, Pino-Yanes M, Graves PE, Villarreal AB, Beaty TH, Carey VJ, Croteau-Chonka DC, del Rio Navarro B, Edlund C, Hernandez-Cadena L,…
• The lung corps' approach to reducing health disparities in respiratory disease.
  Annals of the American Thoracic Society 2014 Thakur N, McGarry ME, Oh SS, Galanter JM, Finn PW, Burchard EG, ATS Health Equality Committee
• Dissecting childhood asthma with nasal transcriptomics distinguishes subphenotypes of disease.
  The Journal of allergy and clinical immunology 2014 Poole A, Urbanek C, Eng C, Schageman J, Jacobson S, O'Connor BP, Galanter JM, Gignoux CR, Roth LA, Kumar R, Lutz S, Liu AH, Fingerlin TE, Setterquist RA, Burchard EG, Rodriguez-Santana J, Seibold MA
• A genome-wide association study of bronchodilator response in Latinos implicates rare variants
  J Allergy Clin Immunol 2014 Drake KA, Torgerson DG, Gignoux CR, Galanter JM, Roth LA, Huntsman S, Eng C, Oh SS, Yee SW, Lin L, Bustamante CD, Moreno-Estrada A, Sandoval K, Davis A, Borrell LN, Farber HJ, Kumar R, Avila PC, …
• Gene-based association identifies SPATA13-AS1 as a pharmacogenomic predictor of inhaled short-acting beta-agonist response in multiple population groups.
  The pharmacogenomics journal 2014 Padhukasahasram B, Yang JJ, Levin AM, Yang M, Burchard EG, Kumar R, Kwok PY, Seibold MA, Lanfear DE, Williams LK
• Genome-wide association study and admixture mapping identify different asthma-associated loci in Latinos: the Genes-environments & Admixture in Latino Americans study.
  The Journal of allergy and clinical immunology 2014 Galanter JM, Gignoux CR, Torgerson DG, Roth LA, Eng C, Oh SS, Nguyen EA, Drake KA, Huntsman S, Hu D, Sen S, Davis A, Farber HJ, Avila PC, Brigino-Buenaventura E, LeNoir MA, Meade K, Serebrisky D, …
• Genome-wide association study of lung function phenotypes in a founder population
  J Allergy Clin Immunol 2014 Yao TC, Du G, Han L, Sun Y, Hu D, Yang JJ, Mathias R, Roth LA, Rafaels N, Thompson EE, Loisel DA, Anderson R, Eng C, Arruabarrena Orbegozo M, Young M, Klocksieben JM, Anderson E, Shanovich K, Lester …
• Reconstructing Native American migrations from whole-genome and whole-exome data.
  PLoS genetics 2013 Gravel S, Zakharia F, Moreno-Estrada A, Byrnes JK, Muzzio M, Rodriguez-Flores JL, Kenny EE, Gignoux CR, Maples BK, Guiblet W, Dutil J, Via M, Sandoval K, Bedoya G, 1000 Genomes Project, Oleksyk TK, …
• Inherited GATA3 variants are associated with Ph-like childhood acute lymphoblastic leukemia and risk of relapse
  Nat Genet. 2013 Perez-Andreu V, Roberts KG, Harvey RC, Yang W, Cheng C, Pei D, Xu H, Gastier-Foster J, E S, Lim JY, Chen IM, Fan Y, Devidas M, Borowitz MJ, Smith C, Neale G, Burchard EG, Torgerson DG, Klussmann FA, …
• Socioeconomic status and childhood asthma in urban minority youths. The GALA II and SAGE II studies.
  American journal of respiratory and critical care medicine 2013 Thakur N, Oh SS, Nguyen EA, Martin M, Roth LA, Galanter J, Gignoux CR, Eng C, Davis A, Meade K, LeNoir MA, Avila PC, Farber HJ, Serebrisky D, Brigino-Buenaventura E, Rodriguez-Cintron W, Kumar R, …
• Reconstructing the population genetic history of the Caribbean.
  PLoS genetics 2013 Moreno-Estrada A, Gravel S, Zakharia F, McCauley JL, Byrnes JK, Gignoux CR, Ortiz-Tello PA, Martínez RJ, Hedges DJ, Morris RW, Eng C, Sandoval K, Acevedo-Acevedo S, Norman PJ, Layrisse Z, Parham P, …
• Early-life air pollution and asthma risk in minority children. The GALA II and SAGE II studies.
  American journal of respiratory and critical care medicine 2013 Nishimura KK, Galanter JM, Roth LA, Oh SS, Thakur N, Nguyen EA, Thyne S, Farber HJ, Serebrisky D, Kumar R, Brigino-Buenaventura E, Davis A, LeNoir MA, Meade K, Rodriguez-Cintron W, Avila PC, Borrell …
• Factors associated with degree of atopy in Latino children in a nationwide pediatric sample: the Genes-environments and Admixture in Latino Asthmatics (GALA II) study.
  The Journal of allergy and clinical immunology 2013 Kumar R, Nguyen EA, Roth LA, Oh SS, Gignoux CR, Huntsman S, Eng C, Moreno-Estrada A, Sandoval K, Peñaloza-Espinosa RI, López-López M, Avila PC, Farber HJ, Tcheurekdjian H, Rodriguez-Cintron W, …
• Analysis of Latino populations from GALA and MEC studies reveals genomic loci with biased local ancestry estimation.
  Bioinformatics (Oxford, England) 2013 Pasaniuc B, Sankararaman S, Torgerson DG, Gignoux C, Zaitlen N, Eng C, Rodriguez-Cintron W, Chapela R, Ford JG, Avila PC, Rodriguez-Santana J, Chen GK, Le Marchand L, Henderson B, Reich D, Haiman CA, …
• Childhood obesity and asthma control in the GALA II and SAGE II studies.
  American journal of respiratory and critical care medicine 2013 Borrell LN, Nguyen EA, Roth LA, Oh SS, Tcheurekdjian H, Sen S, Davis A, Farber HJ, Avila PC, Brigino-Buenaventura E, Lenoir MA, Lurmann F, Meade K, Serebrisky D, Rodriguez-Cintron W, Kumar R, …
• Novel susceptibility variants at 10p12.31-12.2 for childhood acute lymphoblastic leukemia in ethnically diverse populations.
  Journal of the National Cancer Institute 2013 Xu H, Yang W, Perez-Andreu V, Devidas M, Fan Y, Cheng C, Pei D, Scheet P, Burchard EG, Eng C, Huntsman S, Torgerson DG, Dean M, Winick NJ, Martin PL, Camitta BM, Bowman WP, Willman CL, Carroll WL, …
• Integration of mouse and human genome-wide association data identifies KCNIP4 as an asthma gene.
  PloS one 2013 Himes BE, Sheppard K, Berndt A, Leme AS, Myers RA, Gignoux CR, Levin AM, Gauderman WJ, Yang JJ, Mathias RA, Romieu I, Torgerson DG, Roth LA, Huntsman S, Eng C, Klanderman B, Ziniti J, Senter-Sylvia J,…
• A meta-analysis of genome-wide association studies for serum total IgE in diverse study populations.
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• An integrated map of genetic variation from 1,092 human genomes.
  Nature 2012 1000 Genomes Project Consortium, Abecasis GR, Auton A, Brooks LD, DePristo MA, Durbin RM, Handsaker RE, Kang HM, Marth GT, McVean GA
• Genetic ancestry and its association with asthma exacerbations among African American subjects with asthma.
  The Journal of allergy and clinical immunology 2012 Rumpel JA, Ahmedani BK, Peterson EL, Wells KE, Yang M, Levin AM, Yang JJ, Kumar R, Burchard EG, Williams LK
• Population genetic inference from personal genome data: impact of ancestry and admixture on human genomic variation.
  American journal of human genetics 2012 Kidd JM, Gravel S, Byrnes J, Moreno-Estrada A, Musharoff S, Bryc K, Degenhardt JD, Brisbin A, Sheth V, Chen R, McLaughlin SF, Peckham HE, Omberg L, Bormann Chung CA, Stanley S, Pearlstein K, …
• Further replication studies of the EVE Consortium meta-analysis identifies 2 asthma risk loci in European Americans.
  The Journal of allergy and clinical immunology 2012 Myers RA, Himes BE, Gignoux CR, Yang JJ, Gauderman WJ, Rebordosa C, Xie J, Torgerson DG, Levin AM, Baurley J, Graves PE, Mathias RA, Romieu I, Roth LA, Conti D, Avila L, Eng C, Vora H, LeNoir MA, Soto…
• Asthma Research for All of the United States.
  Pediatric allergy, immunology, and pulmonology 2012 Nguyen EA, Burchard EG
• Genetic variation in B cell-activating factor of the TNF family (BAFF) and asthma exacerbations among African American subjects.
  The Journal of allergy and clinical immunology 2012 Kumar R, Williams LK, Kato A, Peterson EL, Favoreto S, Hulse K, Wang D, Beckman K, Thyne S, LeNoir M, Meade K, Lanfear DE, Levin AM, Favro D, Yang JJ, Weiss K, Boushey HA, Grammer L, Avila PC, …
• Genetic ancestry-smoking interactions and lung function in African Americans: a cohort study.
  PloS one 2012 Aldrich MC, Kumar R, Colangelo LA, Williams LK, Sen S, Kritchevsky SB, Meibohm B, Galanter J, Hu D, Gignoux CR, Liu Y, Harris TB, Ziv E, Zmuda J, Garcia M, Leak TS, Foreman MG, Smith LJ, Fornage M, …
• Genome-wide ancestry association testing identifies a common European variant on 6q14.1 as a risk factor for asthma in African American subjects.
  The Journal of allergy and clinical immunology 2012 Torgerson DG, Capurso D, Ampleford EJ, Li X, Moore WC, Gignoux CR, Hu D, Eng C, Mathias RA, Busse WW, Castro M, Erzurum SC, Fitzpatrick AM, Gaston B, Israel E, Jarjour NN, Teague WG, Wenzel SE, …
• Melanesian blond hair is caused by an amino acid change in TYRP1.
  Science (New York, N.Y.) 2012 Kenny EE, Timpson NJ, Sikora M, Yee MC, Moreno-Estrada A, Eng C, Huntsman S, Burchard EG, Stoneking M, Bustamante CD, Myles S
• Effect of secondhand smoke on asthma control among black and Latino children.
  The Journal of allergy and clinical immunology 2012 Oh SS, Tcheurekdjian H, Roth LA, Nguyen EA, Sen S, Galanter JM, Davis A, Farber HJ, Gilliland FD, Kumar R, Avila PC, Brigino-Buenaventura E, Chapela R, Ford JG, LeNoir MA, Lurmann F, Meade K, …
• Case-control admixture mapping in Latino populations enriches for known asthma-associated genes.
  The Journal of allergy and clinical immunology 2012 Torgerson DG, Gignoux CR, Galanter JM, Drake KA, Roth LA, Eng C, Huntsman S, Torres R, Avila PC, Chapela R, Ford JG, Rodríguez-Santana JR, Rodríguez-Cintrón W, Hernandez RD, Burchard EG
• Fast and accurate inference of local ancestry in Latino populations.
  Bioinformatics (Oxford, England) 2012 Baran Y, Pasaniuc B, Sankararaman S, Torgerson DG, Gignoux C, Eng C, Rodriguez-Cintron W, Chapela R, Ford JG, Avila PC, Rodriguez-Santana J, Burchard EG, Halperin E
• Heterogeneity in genetic admixture across different regions of Argentina.
  PloS one 2012 Avena S, Via M, Ziv E, Pérez-Stable EJ, Gignoux CR, Dejean C, Huntsman S, Torres-Mejía G, Dutil J, Matta JL, Beckman K, Burchard EG, Parolin ML, Goicoechea A, Acreche N, Boquet M, Ríos Part Mdel C, …
• Development of a panel of genome-wide ancestry informative markers to study admixture throughout the Americas.
  PLoS genetics 2012 Galanter JM, Fernandez-Lopez JC, Gignoux CR, Barnholtz-Sloan J, Fernandez-Rozadilla C, Via M, Hidalgo-Miranda A, Contreras AV, Figueroa LU, Raska P, Jimenez-Sanchez G, Zolezzi IS, Torres M, Ponte CR, …
• African ancestry, early life exposures, and respiratory morbidity in early childhood
  Clin Exp Allergy 2012 Kumar R, Tsai HJ, Hong X, Gignoux C, Pearson C, Ortiz K, Fu M, Pongracic JA, Burchard EG, Bauchner H, Wang X
• ARID5B genetic polymorphisms contribute to racial disparities in the incidence and treatment outcome of childhood acute lymphoblastic leukemia.
  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2012 Xu H, Cheng C, Devidas M, Pei D, Fan Y, Yang W, Neale G, Scheet P, Burchard EG, Torgerson DG, Eng C, Dean M, Antillon F, Winick NJ, Martin PL, Willman CL, Camitta BM, Reaman GH, Carroll WL, Loh M, …
• Admixture mapping identifies a locus on 6q25 associated with breast cancer risk in US Latinas.
  Human molecular genetics 2012 Fejerman L, Chen GK, Eng C, Huntsman S, Hu D, Williams A, Pasaniuc B, John EM, Via M, Gignoux C, Ingles S, Monroe KR, Kolonel LN, Torres-Mejía G, Pérez-Stable EJ, Burchard EG, Henderson BE, Haiman CA,…
• Genetic association between human chitinases and lung function in COPD.
  Human genetics 2011 Aminuddin F, Akhabir L, Stefanowicz D, Paré PD, Connett JE, Anthonisen NR, Fahy JV, Seibold MA, Burchard EG, Eng C, Gulsvik A, Bakke P, Cho MH, Litonjua A, Lomas DA, Anderson WH, Beaty TH, Crapo JD, …
• Polymorphism in Osteopontin Gene (SPP1) Is Associated with Asthma and Related Phenotypes in a Puerto Rican Population.
  Pediatric allergy, immunology, and pulmonology 2011 Arjomandi M, Galanter JM, Choudhry S, Eng C, Hu D, Beckman K, Chapela R, Rodríguez-Santana JR, Rodríguez-Cintrón W, Ford J, Avila PC, Burchard EG
• Quantifying the proportion of severe asthma exacerbations attributable to inhaled corticosteroid nonadherence.
  The Journal of allergy and clinical immunology 2011 Williams LK, Peterson EL, Wells K, Ahmedani BK, Kumar R, Burchard EG, Chowdhry VK, Favro D, Lanfear DE, Pladevall M
• Identification of KIF3A as a novel candidate gene for childhood asthma using RNA expression and population allelic frequencies differences.
  PloS one 2011 Kovacic MB, Myers JM, Wang N, Martin LJ, Lindsey M, Ericksen MB, He H, Patterson TL, Baye TM, Torgerson D, Roth LA, Gupta J, Sivaprasad U, Gibson AM, Tsoras AM, Hu D, Eng C, Chapela R, Rodríguez-…
• Ethnic variability in persistent asthma after in utero tobacco exposure.
  Pediatrics 2011 Akuete K, Oh SS, Thyne S, Rodriguez-Santana JR, Chapela R, Meade K, Rodriguez-Cintron W, LeNoir M, Ford JG, Williams LK, Avila PC, Burchard EG, Tcheurekdjian H
• Furthering the link between the sarcomere and primary cardiomyopathies: restrictive cardiomyopathy associated with multiple mutations in genes previously associated with hypertrophic or dilated cardiomyopathy.
  American journal of medical genetics. Part A 2011 Caleshu C, Sakhuja R, Nussbaum RL, Schiller NB, Ursell PC, Eng C, De Marco T, McGlothlin D, Burchard EG, Rame JE
• Meta-analysis of genome-wide association studies of asthma in ethnically diverse North American populations.
  Nature genetics 2011 Torgerson DG, Ampleford EJ, Chiu GY, Gauderman WJ, Gignoux CR, Graves PE, Himes BE, Levin AM, Mathias RA, Hancock DB, Baurley JW, Eng C, Stern DA, Celedón JC, Rafaels N, Capurso D, Conti DV, Roth LA, …
• Genomics for the world.
  Nature 2011 Bustamante CD, Burchard EG, De la Vega FM
• Identification of ATPAF1 as a novel candidate gene for asthma in children.
  The Journal of allergy and clinical immunology 2011 Schauberger EM, Ewart SL, Arshad SH, Huebner M, Karmaus W, Holloway JW, Friderici KH, Ziegler JT, Zhang H, Rose-Zerilli MJ, Barton SJ, Holgate ST, Kilpatrick JR, Harley JB, Lajoie-Kadoch S, Harley IT,…
• Cosmopolitan and ethnic-specific replication of genetic risk factors for asthma in 2 Latino populations.
  The Journal of allergy and clinical immunology 2011 Galanter JM, Torgerson D, Gignoux CR, Sen S, Roth LA, Via M, Aldrich MC, Eng C, Huntsman S, Rodriguez-Santana J, Rodriguez-Cintrón W, Chapela R, Ford JG, Burchard EG
• History shaped the geographic distribution of genomic admixture on the island of Puerto Rico.
  PloS one 2011 Via M, Gignoux CR, Roth LA, Fejerman L, Galanter J, Choudhry S, Toro-Labrador G, Viera-Vera J, Oleksyk TK, Beckman K, Ziv E, Risch N, Burchard EG, Martínez-Cruzado JC
• Ethical and practical guidelines for reporting genetic research results to study participants: updated guidelines from a National Heart, Lung, and Blood Institute working group.
  Circulation. Cardiovascular genetics 2010 National Heart, Lung, and Blood Institute working group, Fabsitz RR, McGuire A, Sharp RR, Puggal M, Beskow LM, Biesecker LG, Bookman E, Burke W, Burchard EG, Church G, Clayton EW, Eckfeldt JH, …
• Factors predicting inhaled corticosteroid responsiveness in African American patients with asthma.
  The Journal of allergy and clinical immunology 2010 Gould W, Peterson EL, Karungi G, Zoratti A, Gaggin J, Toma G, Yan S, Levin AM, Yang JJ, Wells K, Wang M, Burke RR, Beckman K, Popadic D, Land SJ, Kumar R, Seibold MA, Lanfear DE, Burchard EG, Williams…
• ALOX5AP and LTA4H polymorphisms modify augmentation of bronchodilator responsiveness by leukotriene modifiers in Latinos.
  The Journal of allergy and clinical immunology 2010 Tcheurekdjian H, Via M, De Giacomo A, Corvol H, Eng C, Thyne S, Chapela R, Rodriguez-Cintron W, Rodriguez-Santana JR, Avila PC, Burchard EG, Genetics of Asthma in Latino Americans Study
• Dual-specificity phosphatase 1 as a pharmacogenetic modifier of inhaled steroid response among asthmatic patients.
  The Journal of allergy and clinical immunology 2010 Jin Y, Hu D, Peterson EL, Eng C, Levin AM, Wells K, Beckman K, Kumar R, Seibold MA, Karungi G, Zoratti A, Gaggin J, Campbell J, Galanter J, Chapela R, Rodríguez-Santana JR, Watson HG, Meade K, Lenoir …
• Genetic ancestry in lung-function predictions.
  The New England journal of medicine 2010 Kumar R, Seibold MA, Aldrich MC, Williams LK, Reiner AP, Colangelo L, Galanter J, Gignoux C, Hu D, Sen S, Choudhry S, Peterson EL, Rodriguez-Santana J, Rodriguez-Cintron W, Nalls MA, Leak TS, O'Meara …
• GSNO reductase and beta2-adrenergic receptor gene-gene interaction: bronchodilator responsiveness to albuterol.
  Pharmacogenetics and genomics 2010 Choudhry S, Que LG, Yang Z, Liu L, Eng C, Kim SO, Kumar G, Thyne S, Chapela R, Rodriguez-Santana JR, Rodriguez-Cintron W, Avila PC, Stamler JS, Burchard EG
• A genome-wide association study on African-ancestry populations for asthma
  J Allergy Clin Immunol 2010 Mathias RA, Grant AV, Rafaels N, Hand T, Gao L, Vergara C, Tsai YJ, Yang M, Campbell M, Foster C, Gao P, Togias A, Hansel NN, Diette G, Adkinson NF, Liu MC, Faruque M, Dunston GM, Watson HR, Bracken …
• The 1000 Genomes Project: new opportunities for research and social challenges.
  Genome medicine 2010 Via M, Gignoux C, Burchard EG
• The role of LTA4H and ALOX5AP genes in the risk for asthma in Latinos.
  Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2010 Via M, De Giacomo A, Corvol H, Eng C, Seibold MA, Gillett C, Galanter J, Sen S, Tcheurekdjian H, Chapela R, Rodríguez-Santana JR, Rodríguez-Cintrón W, Thyne S, Avila PC, Choudhry S, González Burchard …
• Ancestry-related assortative mating in Latino populations.
  Genome biology 2009 Risch N, Choudhry S, Via M, Basu A, Sebro R, Eng C, Beckman K, Thyne S, Chapela R, Rodriguez-Santana JR, Rodriguez-Cintron W, Avila PC, Ziv E, Gonzalez Burchard E
• Institutional Profile: The University of California Pharmacogenomics Center: at the interface of genomics, biological mechanisms and drug therapy.
  Pharmacogenomics 2009 Kroetz DL, Ahituv N, Burchard EG, Guo S, Sali A, Giacomini KM
• Recent advances of genetic ancestry testing in biomedical research and direct to consumer testing.
  Clinical genetics 2009 Via M, Ziv E, Burchard EG
• Genome-wide association study implicates chromosome 9q21.31 as a susceptibility locus for asthma in mexican children.
  PLoS genetics 2009 Hancock DB, Romieu I, Shi M, Sienra-Monge JJ, Wu H, Chiu GY, Li H, del Rio-Navarro BE, Willis-Owen SA, Willis-Owens SA, Weiss ST, Raby BA, Gao H, Eng C, Chapela R, Burchard EG, Tang H, Sullivan PF, …
• Effect of genetic variation in the organic cation transporter 2 on the renal elimination of metformin.
  Pharmacogenetics and genomics 2009 Chen Y, Li S, Brown C, Cheatham S, Castro RA, Leabman MK, Urban TJ, Chen L, Yee SW, Choi JH, Huang Y, Brett CM, Burchard EG, Giacomini KM
• Genetic ancestry modifies pharmacogenetic gene-gene interaction for asthma.
  Pharmacogenetics and genomics 2009 Corvol H, De Giacomo A, Eng C, Seibold M, Ziv E, Chapela R, Rodriguez-Santana JR, Rodriguez-Cintron W, Thyne S, Watson HG, Meade K, LeNoir M, Avila PC, Choudhry S, Burchard EG, Genetics of Asthma in …
• Augmentation of bronchodilator responsiveness by leukotriene modifiers in Puerto Rican and Mexican children.
  Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 2009 Tcheurekdjian H, Thyne SM, Williams LK, Via M, Rodriguez-Santana JR, Rodriguez-Cintron W, Avila PC, Burchard EG
• Differential enzymatic activity of common haplotypic versions of the human acidic Mammalian chitinase protein.
  The Journal of biological chemistry 2009 Seibold MA, Reese TA, Choudhry S, Salam MT, Beckman K, Eng C, Atakilit A, Meade K, Lenoir M, Watson HG, Thyne S, Kumar R, Weiss KB, Grammer LC, Avila P, Schleimer RP, Fahy JV, Rodriguez-Santana J, …
• Race and ancestry in biomedical research: exploring the challenges.
  Genome medicine 2009 Caulfield T, Fullerton SM, Ali-Khan SE, Arbour L, Burchard EG, Cooper RS, Hardy BJ, Harry S, Hyde-Lay R, Kahn J, Kittles R, Koenig BA, Lee SS, Malinowski M, Ravitsky V, Sankar P, Scherer SW, Séguin B,…
• Birthplace and mortality among insured Latinos: the paradox revisited.
  Ethnicity & disease 2009 Iribarren C, Darbinian JA, Fireman BH, Burchard EG
• Population admixture associated with disease prevalence in the Boston Puerto Rican health study.
  Human genetics 2008 Lai CQ, Tucker KL, Choudhry S, Parnell LD, Mattei J, García-Bailo B, Beckman K, Burchard EG, Ordovás JM
• Common variants in interleukin-1-Beta gene are associated with intracranial hemorrhage and susceptibility to brain arteriovenous malformation.
  Cerebrovascular diseases (Basel, Switzerland) 2008 Kim H, Hysi PG, Pawlikowska L, Poon A, Burchard EG, Zaroff JG, Sidney S, Ko NU, Achrol AS, Lawton MT, McCulloch CE, Kwok PY, Young WL
• Genetic ancestry and risk of breast cancer among U.S. Latinas.
  Cancer research 2008 Fejerman L, John EM, Huntsman S, Beckman K, Choudhry S, Perez-Stable E, Burchard EG, Ziv E
• Relationship between recent short-acting beta-agonist use and subsequent asthma exacerbations.
  Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 2008 Paris J, Peterson EL, Wells K, Pladevall M, Burchard EG, Choudhry S, Lanfear DE, Williams LK
• Chitotriosidase is the primary active chitinase in the human lung and is modulated by genotype and smoking habit.
  The Journal of allergy and clinical immunology 2008 Seibold MA, Donnelly S, Solon M, Innes A, Woodruff PG, Boot RG, Burchard EG, Fahy JV
• Differences in allergic sensitization by self-reported race and genetic ancestry.
  The Journal of allergy and clinical immunology 2008 Yang JJ, Burchard EG, Choudhry S, Johnson CC, Ownby DR, Favro D, Chen J, Akana M, Ha C, Kwok PY, Krajenta R, Havstad SL, Joseph CL, Seibold MA, Shriver MD, Williams LK
• An african-specific functional polymorphism in KCNMB1 shows sex-specific association with asthma severity.
  Human molecular genetics 2008 Seibold MA, Wang B, Eng C, Kumar G, Beckman KB, Sen S, Choudhry S, Meade K, Lenoir M, Watson HG, Thyne S, Williams LK, Kumar R, Weiss KB, Grammer LC, Avila PC, Schleimer RP, Burchard EG, Brenner R
• Comparing genetic ancestry and self-described race in african americans born in the United States and in Africa.
  Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2008 Yaeger R, Avila-Bront A, Abdul K, Nolan PC, Grann VR, Birchette MG, Choudhry S, Burchard EG, Beckman KB, Gorroochurn P, Ziv E, Consedine NS, Joe AK
• Inhaled corticosteroids and augmented bronchodilator responsiveness in Latino and African American asthmatic patients.
  Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 2008 Naqvi M, Tcheurekdjian H, DeBoard JA, Williams LK, Navarro D, Castro RA, Rodriguez-Santana JR, Chapela R, Watson HG, Meade K, Rodriguez-Cintron W, LeNoir M, Thyne SM, Avila PC, Choudhry S, Burchard EG
• Pharmacogenetic response to albuterol among asthmatics
  Pharmacogenomics 2008 Corvol H, Burchard EG
• Genome-wide screen for asthma in Puerto Ricans: evidence for association with 5q23 region.
  Human genetics 2008 Choudhry S, Taub M, Mei R, Rodriguez-Santana J, Rodriguez-Cintron W, Shriver MD, Ziv E, Risch NJ, Burchard EG
• Race, ethnicity and social class and the complex etiologies of asthma.
  Pharmacogenomics 2008 Drake KA, Galanter JM, Burchard EG
• ORMDL3 gene is associated with asthma in three ethnically diverse populations.
  American journal of respiratory and critical care medicine 2008 Galanter J, Choudhry S, Eng C, Nazario S, Rodríguez-Santana JR, Casal J, Torres-Palacios A, Salas J, Chapela R, Watson HG, Meade K, LeNoir M, Rodríguez-Cintrón W, Avila PC, Burchard EG
• Effect of genetic variation in the organic cation transporter 1, OCT1, on metformin pharmacokinetics
  Clin Pharmacol Ther 2008 Shu Y, Brown C, Castro RA, Shi RJ, Lin ET, Owen RP, Sheardown SA, Yue L, Burchard EG, Brett CM, Giacomini KM
• Gene-environment interactions between CD14 C-260T and endotoxin exposure on Foxp3+ and Foxp3- CD4+ lymphocyte numbers and total serum IgE levels in early childhood.
  Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 2008 Williams LK, Oliver J, Peterson EL, Bobbitt KR, McCabe MJ, Smolarek D, Havstad SL, Wegienka G, Burchard EG, Ownby DR, Johnson CC
• Latino populations: a unique opportunity for epidemiological research of asthma.
  Paediatric and perinatal epidemiology 2007 Salari K, Burchard EG
• Ethnic-specific differences in bronchodilator responsiveness among African Americans, Puerto Ricans, and Mexicans with asthma.
  The Journal of asthma : official journal of the Association for the Care of Asthma 2007 Naqvi M, Thyne S, Choudhry S, Tsai HJ, Navarro D, Castro RA, Nazario S, Rodriguez-Santana JR, Casal J, Torres A, Chapela R, Watson HG, Meade K, LeNoir M, Avila PC, Rodriguez-Cintron W, Burchard EG
• Functional effects of protein sequence polymorphisms in the organic cation/ergothioneine transporter OCTN1 (SLC22A4).
  Pharmacogenetics and genomics 2007 Urban TJ, Yang C, Lagpacan LL, Brown C, Castro RA, Taylor TR, Huang CC, Stryke D, Johns SJ, Kawamoto M, Carlson EJ, Ferrin TE, Burchard EG, Giacomini KM
• PCA-correlated SNPs for structure identification in worldwide human populations.
  PLoS genetics 2007 Paschou P, Ziv E, Burchard EG, Choudhry S, Rodriguez-Cintron W, Mahoney MW, Drineas P
• Recent genetic selection in the ancestral admixture of Puerto Ricans.
  American journal of human genetics 2007 Tang H, Choudhry S, Mei R, Morgan M, Rodriguez-Cintron W, Burchard EG, Risch NJ
• Effects of genetic variation in the novel organic cation transporter, OCTN1, on the renal clearance of gabapentin.
  Clinical pharmacology and therapeutics 2007 Urban TJ, Brown C, Castro RA, Shah N, Mercer R, Huang Y, Brett CM, Burchard EG, Giacomini KM
• Dissecting complex diseases in complex populations: asthma in latino americans.
  Proceedings of the American Thoracic Society 2007 Choudhry S, Seibold MA, Borrell LN, Tang H, Serebrisky D, Chapela R, Rodriguez-Santana JR, Avila PC, Ziv E, Rodriguez-Cintron W, Risch NJ, Burchard EG
• Association between IgE levels and asthma severity among African American, Mexican, and Puerto Rican patients with asthma.
  The Journal of allergy and clinical immunology 2007 Naqvi M, Choudhry S, Tsai HJ, Thyne S, Navarro D, Nazario S, Rodriguez-Santana JR, Casal J, Torres A, Chapela R, Watson HG, Meade K, Rodriguez-Cintron W, Lenoir M, Avila PC, Burchard EG
• Effect of genetic variation in the organic cation transporter 1 (OCT1) on metformin action.
  The Journal of clinical investigation 2007 Shu Y, Sheardown SA, Brown C, Owen RP, Zhang S, Castro RA, Ianculescu AG, Yue L, Lo JC, Burchard EG, Brett CM, Giacomini KM
• Determinants of airflow obstruction in severe alpha-1-antitrypsin deficiency.
  Thorax 2007 Demeo DL, Sandhaus RA, Barker AF, Brantly ML, Eden E, McElvaney NG, Rennard S, Burchard E, Stocks JM, Stoller JK, Strange C, Turino GM, Campbell EJ, Silverman EK
• Ethnicity-specific gene-gene interaction between IL-13 and IL-4Ralpha among African Americans with asthma.
  American journal of respiratory and critical care medicine 2007 Battle NC, Choudhry S, Tsai HJ, Eng C, Kumar G, Beckman KB, Naqvi M, Meade K, Watson HG, Lenoir M, Burchard EG, SAGE Investigators
• African ancestry, socioeconomic status, and kidney function in elderly African Americans: a genetic admixture analysis.
  Journal of the American Society of Nephrology : JASN 2006 Peralta CA, Ziv E, Katz R, Reiner A, Burchard EG, Fried L, Kwok PY, Psaty B, Shlipak M
• Genetic ancestry and risk factors for breast cancer among Latinas in the San Francisco Bay Area.
  Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2006 Ziv E, John EM, Choudhry S, Kho J, Lorizio W, Perez-Stable EJ, Burchard EG
• The PTGDR gene is not associated with asthma in 3 ethnically diverse populations.
  The Journal of allergy and clinical immunology 2006 Tsai YJ, Choudhry S, Kho J, Beckman K, Tsai HJ, Navarro D, Matallana H, Castro RA, Lilly CM, Nazario S, Rodriguez-Santana JR, Casal J, Torres A, Salas J, Chapela R, Watson HG, Meade K, Avila PC, …
• Ancestry-environment interactions and asthma risk among Puerto Ricans.
  American journal of respiratory and critical care medicine 2006 Choudhry S, Burchard EG, Borrell LN, Tang H, Gomez I, Naqvi M, Nazario S, Torres A, Casal J, Martinez-Cruzado JC, Ziv E, Avila PC, Rodriguez-Cintron W, Risch NJ
• Functional genetic diversity in the high-affinity carnitine transporter OCTN2 (SLC22A5).
  Molecular pharmacology 2006 Urban TJ, Gallagher RC, Brown C, Castro RA, Lagpacan LL, Brett CM, Taylor TR, Carlson EJ, Ferrin TE, Burchard EG, Packman S, Giacomini KM
• Array comparative genomic hybridization in patients with congenital diaphragmatic hernia: mapping of four CDH-critical regions and sequencing of candidate genes at 15q26.1-15q26.2.
  European journal of human genetics : EJHG 2006 Slavotinek AM, Moshrefi A, Davis R, Leeth E, Schaeffer GB, Burchard GE, Shaw GM, James B, Ptacek L, Pennacchio LA
• Interaction of methotrexate with organic-anion transporting polypeptide 1A2 and its genetic variants.
  The Journal of pharmacology and experimental therapeutics 2006 Badagnani I, Castro RA, Taylor TR, Brett CM, Huang CC, Stryke D, Kawamoto M, Johns SJ, Ferrin TE, Carlson EJ, Burchard EG, Giacomini KM
• Beta 2-adrenergic receptor polymorphisms: pharmacogenetic response to bronchodilator among African American asthmatics.
  Human genetics 2006 Tsai HJ, Shaikh N, Kho JY, Battle N, Naqvi M, Navarro D, Matallana H, Lilly CM, Eng CS, Kumar G, Thyne S, Watson HG, Meade K, LeNoir M, Choudhry S, Burchard EG, Study of African Americans, Asthma, …
• PharmGKB submission update: V. PMT submissions of genetic variation in SLC22 family transporters.
  Pharmacological reviews 2006 Shu Y, Urban TJ, Leabman MK, Fujita T, Erdman AR, Lagpacan LL, Brown C, Castro RA, Huang CC, Stryke D, Kawamoto M, Johns SJ, Taylor TR, Chan W, De La Cruz M, Carlson EJ, Ferrin TE, Brett CM, Burchard …
• PharmGKB submission update: VI. PMT submissions of genetic variations in neurotransmitter transporters (SLC6, SLC17, and SLC18) to the PharmGKB network.
  Pharmacological reviews 2006 Badagnani I, Sorani M, Edwards RH, Brown C, Castro RA, Huang CC, Stryke D, Kawamoto M, Johns SJ, Carlson EJ, Taylor T, Chan W, De La Cruz M, Ferrin TE, Burchard EG, Herskowitz I, Kroetz DL, Giacomini …
• The human organic anion transporter 3 (OAT3; SLC22A8): genetic variation and functional genomics.
  American journal of physiology. Renal physiology 2005 Erdman AR, Mangravite LM, Urban TJ, Lagpacan LL, Castro RA, de la Cruz M, Chan W, Huang CC, Johns SJ, Kawamoto M, Stryke D, Taylor TR, Carlson EJ, Ferrin TE, Brett CM, Burchard EG, Giacomini KM
• Population stratification confounds genetic association studies among Latinos.
  Human genetics 2005 Choudhry S, Coyle NE, Tang H, Salari K, Lind D, Clark SL, Tsai HJ, Naqvi M, Phong A, Ung N, Matallana H, Avila PC, Casal J, Torres A, Nazario S, Castro R, Battle NC, Perez-Stable EJ, Kwok PY, Sheppard…
• Admixture-matched case-control study: a practical approach for genetic association studies in admixed populations.
  Human genetics 2005 Tsai HJ, Kho JY, Shaikh N, Choudhry S, Naqvi M, Navarro D, Matallana H, Castro R, Lilly CM, Watson HG, Meade K, Lenoir M, Thyne S, Ziv E, Burchard EG
• Comparison of three methods to estimate genetic ancestry and control for stratification in genetic association studies among admixed populations.
  Human genetics 2005 Tsai HJ, Choudhry S, Naqvi M, Rodriguez-Cintron W, Burchard EG, Ziv E
• Polymorphisms in transforming growth factor-beta-related genes ALK1 and ENG are associated with sporadic brain arteriovenous malformations.
  Stroke 2005 Pawlikowska L, Tran MN, Achrol AS, Ha C, Burchard E, Choudhry S, Zaroff J, Lawton MT, Castro R, McCulloch CE, Marchuk D, Kwok PY, Young WL, UCSF BAVM Study Project
• Genetic admixture and asthma-related phenotypes in Mexican American and Puerto Rican asthmatics.
  Genetic epidemiology 2005 Salari K, Choudhry S, Tang H, Naqvi M, Lind D, Avila PC, Coyle NE, Ung N, Nazario S, Casal J, Torres-Palacios A, Clark S, Phong A, Gomez I, Matallana H, Pérez-Stable EJ, Shriver MD, Kwok PY, Sheppard …
• CD14 tobacco gene-environment interaction modifies asthma severity and immunoglobulin E levels in Latinos with asthma.
  American journal of respiratory and critical care medicine 2005 Choudhry S, Avila PC, Nazario S, Ung N, Kho J, Rodriguez-Santana JR, Casal J, Tsai HJ, Torres A, Ziv E, Toscano M, Sylvia JS, Alioto M, Salazar M, Gomez I, Fagan JK, Salas J, Lilly C, Matallana H, …
• Functional analysis of polymorphisms in the organic anion transporter, SLC22A6 (OAT1).
  Pharmacogenetics and genomics 2005 Fujita T, Brown C, Carlson EJ, Taylor T, de la Cruz M, Johns SJ, Stryke D, Kawamoto M, Fujita K, Castro R, Chen CW, Lin ET, Brett CM, Burchard EG, Ferrin TE, Huang CC, Leabman MK, Giacomini KM
• Population structure, admixture, and aging-related phenotypes in African American adults: the Cardiovascular Health Study.
  American journal of human genetics 2005 Reiner AP, Ziv E, Lind DL, Nievergelt CM, Schork NJ, Cummings SR, Phong A, Burchard EG, Harris TB, Psaty BM, Kwok PY
• Functional analysis of genetic variants in the human concentrative nucleoside transporter 3 (CNT3; SLC28A3).
  The pharmacogenomics journal 2005 Badagnani I, Chan W, Castro RA, Brett CM, Huang CC, Stryke D, Kawamoto M, Johns SJ, Ferrin TE, Carlson EJ, Burchard EG, Giacomini KM
• Pharmacogenetic differences in response to albuterol between Puerto Ricans and Mexicans with asthma.
  American journal of respiratory and critical care medicine 2004 Choudhry S, Ung N, Avila PC, Ziv E, Nazario S, Casal J, Torres A, Gorman JD, Salari K, Rodriguez-Santana JR, Toscano M, Sylvia JS, Alioto M, Castro RA, Salazar M, Gomez I, Fagan JK, Salas J, Clark S, …
• Lower bronchodilator responsiveness in Puerto Rican than in Mexican subjects with asthma.
  American journal of respiratory and critical care medicine 2003 Burchard EG, Avila PC, Nazario S, Casal J, Torres A, Rodriguez-Santana JR, Toscano M, Sylvia JS, Alioto M, Salazar M, Gomez I, Fagan JK, Salas J, Lilly C, Matallana H, Ziv E, Castro R, Selman M, …
• ADAM33 is not associated with asthma in Puerto Rican or Mexican populations.
  American journal of respiratory and critical care medicine 2003 Lind DL, Choudhry S, Ung N, Ziv E, Avila PC, Salari K, Ha C, Lovins EG, Coyle NE, Nazario S, Casal J, Torres A, Rodriguez-Santana JR, Matallana H, Lilly CM, Salas J, Selman M, Boushey HA, Weiss ST, …
• Human population structure and genetic association studies.
  Pharmacogenomics 2003 Ziv E, Burchard EG
• The importance of race and ethnic background in biomedical research and clinical practice.
  The New England journal of medicine 2003 Burchard EG, Ziv E, Coyle N, Gomez SL, Tang H, Karter AJ, Mountain JL, Pérez-Stable EJ, Sheppard D, Risch N
• Categorization of humans in biomedical research: genes, race and disease.
  Genome biology 2002 Risch N, Burchard E, Ziv E, Tang H
• Association between a sequence variant in the IL-4 gene promoter and FEV(1) in asthma.
  American journal of respiratory and critical care medicine 1999 Burchard EG, Silverman EK, Rosenwasser LJ, Borish L, Yandava C, Pillari A, Weiss ST, Hasday J, Lilly CM, Ford JG, Drazen JM
• Cytokine gene expression in human cardiac allograft recipients.
  Transplant immunology 1994 Wu CJ, Kurbegov D, Lattin B, Burchard E, Finkle C, Valantine H, Billingham ME, Starnes VA, Clayberger C
• Cytokine gene expression in human lung transplant recipients.
  Transplantation 1993 Whitehead BF, Stoehr C, Wu CJ, Patterson G, Burchard EG, Theodore J, Clayberger C, Starnes VA