Ernesto Gonzalez-Giraldo, MD
Assistant Professor
Neurology
School of Medicine
Dr. Ernesto Gonzalez-Giraldo is a pediatric neurologist who cares for children with epilepsy. He specializes in treating patients whose seizures have failed to respond to initial anti-seizure medications. He evaluates patients for epilepsy surgery, including the placement of devices that treat seizures by stimulating the vagus nerve or by responsive neurostimulation.
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He also has a special interest in treating epilepsy with the ketogenic diet, a low carbohydrate, high-fat diet that has been shown to reduce seizures in patients with drug-resistant epilepsy.
His research focuses on treating infantile spasms, a seizure disorder that arises in the first year of life and can severely impact development and cognition if not treated early. He also studies various anti-seizure medications and the ketogenic diet to evaluate their effectiveness in treating epilepsy.
He earned his medical degree from the Perelman School of Medicine at the University of Pennsylvania. He completed a residency in pediatrics at the Sinai Hospital in Baltimore and a residency in child neurology at the Johns Hopkins Hospital. He completed a fellowship in epilepsy at Children's Hospital of Philadelphia.
He belongs to the American Academy of Neurology and American Epilepsy Society.
Awards
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- American Epilepsy Society Fellows Program Award, Children's Hospital of Philadelphia, 2018
- American Academy of Neurology Annual Meeting Scholarship, Johns Hopkins University, 2018
- Frank L. Coulson, Jr. Award for Clinical Excellence, Johns Hopkins University, 2018
- Guy M. McKhann Education in Neurology Award, Johns Hopkins University, 2018
- Kevin Hearney and Judi Marvel Summer Brain Tumor Fellowship, University of Pennsylvania, 2014
- Oliva Teaching Fellowship, Phillips Academy at Andover, MA, 2009
- Howard Hughes Medical Institute Scholarship, Howard Hughes Medical Institute, 2004-2005
Education & Training
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- Epilepsy Fellowship Children's Hospital of Philadelphia 07/2019
- Child Neurology Residency Johns Hopkins University 06/2018
- Pediatrics Residency Herman and Walter Samuelson Children's Hospital at Sinai 06/2015
- MD University of Pennsylvania, Perelman School of Medicine 06/2013
- A.B. Neurobiology Harvard College 05/2008
Interests
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- Drug-resistant Epilepsy
- Infantile Spasms
- Epilepsy
- Autoimmune Epilepsy
- Ketogenic Diet
Publications (14)
Top publication keywords:
AnticonvulsantsSeizuresDrug Resistant EpilepsyElectric Stimulation TherapySpasms, InfantilePrednisoloneAutoimmune Diseases of the Nervous SystemEpilepsyAdrenal Cortex HormonesClinical Decision-MakingMyelin-Oligodendrocyte GlycoproteinLennox Gastaut SyndromePsychosurgeryEncephalitisEpilepsies, Myoclonic
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A multi-center comparison of surgical techniques for corpus Callosotomy in pediatric drug-resistant epilepsy.
Epilepsia 2023 Hansen D, Shandley S, Olaya J, Hauptman J, Auguste K, Ostendorf AP, Depositario-Cabacar DF, Wong-Kisiel LC, Reddy SB, McCormack MJ, Gonzalez-Giraldo E, Sullivan J, Pradeep J, Singh RK, Romanowski EF, … -
Epilepsy surgery in children with genetic etiologies: A prospective evaluation of current practices and outcomes.
Seizure 2023 Coryell J, Singh R, Ostendorf AP, Eisner M, Alexander A, Eschbach K, Shrey DW, Olaya J, Ciliberto MA, Karakas C, Karia S, McNamara N, Romanowski EF, Kheder A, Pradeep J, Reddy SB, McCormack MJ, Bolton… -
Responsive Neurostimulation in Drug-Resistant Pediatric Epilepsy: Findings From the Epilepsy Surgery Subgroup of the Pediatric Epilepsy Research Consortium.
Pediatric neurology 2023 Singh RK, Eschbach K, Samanta D, Perry MS, Liu G, Alexander AL, Wong-Kisiel L, Ostendorf A, Tatachar P, Reddy SB, McCormack MJ, Manuel CM, Gonzalez-Giraldo E, Numis AL, Wolf S, Karia S, Karakas C, … -
Genetic Testing to Inform Epilepsy Treatment Management From an International Study of Clinical Practice.
JAMA neurology 2022 McKnight D, Morales A, Hatchell KE, Bristow SL, Bonkowsky JL, Perry MS, Berg AT, Borlot F, Esplin ED, Moretz C, Angione K, Ríos-Pohl L, Nussbaum RL, Aradhya S, ELEVIATE Consortium, Haldeman-Englert CR… -
Surgical evaluation in children <3 years of age with drug-resistant epilepsy: Patient characteristics, diagnostic utilization, and potential for treatment delays.
Epilepsia 2021 Perry MS, Shandley S, Perelman M, Singh RK, Wong-Kisiel L, Sullivan J, Gonzalez-Giraldo E, Romanowski EF, McNamara NA, Marashly A, Ostendorf AP, Alexander A, Eschbach K, Bolton J, Wolf S, McGoldrick P…
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Acceptability of Standardized EEG Reporting in an Electronic Health Record.
Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society 2020 Witzman S, Massey SL, Kessler S, Gonzalez-Giraldo E, Fridinger SE, Worden L, Lewin N, Dlugos D, Melamed S, Fitzgerald M, Fung FW, Ferruzi M, McNamee N, LaFalce D, Donnelly M, Haywood A, Allen-Napoli L… -
Clinical Reasoning: An 11-year-old girl with focal seizures, fevers, and unilateral, enhancing cortical lesions.
Neurology 2020 Russ JB, Timbie CM, Li Y, Gonzalez-Giraldo E -
Tablet-based electroencephalography diagnostics for patients with epilepsy in the West African Republic of Guinea.
European journal of neurology 2020 Sokolov E, Abdoul Bachir DH, Sakadi F, Williams J, Vogel AC, Schaekermann M, Tassiou N, Bah AK, Khatri V, Hotan GC, Ayub N, Leung E, Fantaneanu TA, Patel A, Vyas M, Milligan T, Villamar MF, Hoch D, … -
Advances in the Treatment of Drug-Resistant Pediatric Epilepsy.
Seminars in neurology 2020 Gonzalez-Giraldo E, Sullivan JE -
Reply to Sharawat et al. "Efficacy of High-Dose Oral Steroids in Children With Epileptic Spasms".
Pediatric neurology 2019 Gonzalez-Giraldo E, Stafstrom CE, Stanfield AC, Kossoff EH -
Treating Infantile Spasms with High-Dose Oral Corticosteroids: A Retrospective Review of 87 Children.
Pediatric neurology 2018 Gonzalez-Giraldo E, Stafstrom CE, Stanfield AC, Kossoff EH -
Recurrent Dysarthria and Ataxia in a Young Girl.
JAMA neurology 2018 Romba M, González-Giraldo E, Levy M -
Scoring system for periventricular leukomalacia in infants with congenital heart disease.
Pediatric research 2015 McCarthy AL, Winters ME, Busch DR, Gonzalez-Giraldo E, Ko TS, Lynch JM, Schwab PJ, Xiao R, Buckley EM, Vossough A, Licht DJ -
Brachial plexus injury mimicking a spinal-cord injury.
Evidence-based spine-care journal 2010 Macyszyn LJ, Gonzalez-Giraldo E, Aversano M, Heuer GG, Zager EL, Schuster JM