Eric Verdin, MD
Professor
Medicine
School of Medicine
Grants and Projects
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- The University of Southern California and Buck Institute Nathan Shock Center, NIH, 2020-2025
- Genetic dissection of trait variation between long-diverged mouse species, NIH, 2019-2024
- Molecular Mechanisms of HIV Latency, NIH, 2016-2022
- Identification of HIV latency biomarkers with a dual fluorescence reporter HIV, NIH, 2015-2021
- Novel model for HIV Latency in Oral Primary Lymphoid Tissues, NIH, 2016-2021
- Reversible Mitochondrial Protein Acetylation and Metabolic Regulation, NIH, 2010-2020
- Lysine Malonylation and SIRT5 in Epigenetic Regulation, NIH, 2016-2017
- Martin Delaney Collaboratory to Eradicate HIV-1 Infection, NIH, 2011-2016
- Novel Model for HIV Latency in Primary Memory T Cells, NIH, 2010-2016
- Epigenetic regulation of HIV latency, NIH, 2010-2016
- Bio-Organic Biomedical Mass Spectrometry Resource, NIH, 1982-2015
- California National Primate Research Center, NIH, 1975-2015
- Role of Chromatin in HIV Transcriptional Regulation, NIH, 1995-2012
- Role of HDAC7 in T-cell Development, NIH, 2010-2012
- STRUCTURE-BASED DESIGN PARADIGM:HIV Tat.PCAF INHIBITORS, NIH, 2002-2010
- Molecular Mechanisms of HIV Post-Integration Latency, NIH, 2004-2010
- Regulation of HIV transcription and replication by SDF-1gamma, NIH, 2005-2007
- A New In Vitro Model for HIV Latency, NIH, 2003-2005
- Modulation of Cd8 T Cell Function by Hiv Envelope Protei, NIH, 1999-2004
- Modulation of T Cell Functions by Hiv1 Tat, NIH, 1997-2003
Publications (303)
Top publication keywords:
AcetylationHistone DeacetylasesSirtuinsNADPlant DiseasesSirtuin 3LongevityGene Expression Regulation, ViralMitochondrial ProteinsHIV-13-Hydroxybutyric AcidMitochondriaVirus LatencyHistone Deacetylase InhibitorsAging
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Biological and Genetic Characterization of Physostegia Chlorotic Mottle Virus in Europe Based on Host Range, Location, and Time.
Plant disease 2022 Temple C, Blouin AG, De Jonghe K, Foucart Y, Botermans M, Westenberg M, Schoen R, Gentit P, Visage M, Verdin E, Wipf-Scheibel C, Ziebell H, Gaafar YZA, Zia A, Yan XH, Richert-Pöggeler KR, Ulrich R, … -
Identification of a novel vitivirus from pineapple in Reunion Island.
Archives of virology 2022 Massé D, Filloux D, Candresse T, Massart S, Marais A, Verdin E, Cassam N, Fernandez E, Roumagnac P, Teycheney PY, Lefeuvre P, Lett JM -
The intestinal immune system and gut barrier function in obesity and ageing.
The FEBS journal 2022 Shemtov SJ, Emani R, Bielska O, Covarrubias AJ, Verdin E, Andersen JK, Winer DA -
T cell stimulation remodels the latently HIV-1 infected cell population by differential activation of proviral chromatin.
PLoS pathogens 2022 Lindqvist B, Jütte BB, Love L, Assi W, Roux J, Sönnerborg A, Tezil T, Verdin E, Svensson JP -
A proposed unified mitotic chromosome architecture.
Proceedings of the National Academy of Sciences of the United States of America 2022 Sedat J, McDonald A, Kasler H, Verdin E, Cang H, Arigovindan M, Murre C, Elbaum M
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SIRT5 is a proviral factor that interacts with SARS-CoV-2 Nsp14 protein.
bioRxiv : the preprint server for biology 2022 Walter M, Chen IP, Vallejo-Gracia A, Kim IJ, Bielska O, Lam VL, Hayashi JM, Cruz A, Shah S, Gross JD, Krogan NJ, Schilling B, Ott M, Verdin E -
Characterising proteolysis during SARS-CoV-2 infection identifies viral cleavage sites and cellular targets with therapeutic potential.
Nature communications 2021 Meyer B, Chiaravalli J, Gellenoncourt S, Brownridge P, Bryne DP, Daly LA, Grauslys A, Walter M, Agou F, Chakrabarti LA, Craik CS, Eyers CE, Eyers PA, Gambin Y, Jones AR, Sierecki E, Verdin E, Vignuzzi… -
SARS-CoV-2, COVID-19 and the Ageing Immune System.
Nature aging 2021 Bartleson JM, Radenkovic D, Covarrubias AJ, Furman D, Winer DA, Verdin E -
The Effect of JAK1/2 Inhibitors on HIV Reservoir Using Primary Lymphoid Cell Model of HIV Latency.
Frontiers in immunology 2021 de Armas LR, Gavegnano C, Pallikkuth S, Rinaldi S, Pan L, Battivelli E, Verdin E, Younis RT, Pahwa R, Williams SL, Schinazi RF, Pahwa S -
University of Southern California and buck institute nathan shock center: multidimensional models of aging.
GeroScience 2021 Curran SP, Lithgow GJ, Verdin E, P C -
Targeting Conserved Sequences Circumvents the Evolution of Resistance in a Viral Gene Drive against Human Cytomegalovirus.
Journal of virology 2021 Walter M, Perrone R, Verdin E -
Metabolic Rewiring by Loss of Sirt5 Promotes Kras-Induced Pancreatic Cancer Progression.
Gastroenterology 2021 Hu T, Shukla SK, Vernucci E, He C, Wang D, King RJ, Jha K, Siddhanta K, Mullen NJ, Attri KS, Murthy D, Chaika NV, Thakur R, Mulder SE, Pacheco CG, Fu X, High RR, Yu F, Lazenby A, Steegborn C, Lan P, … -
Moving geroscience from the bench to clinical care and health policy.
Journal of the American Geriatrics Society 2021 Sierra F, Caspi A, Fortinsky RH, Haynes L, Lithgow GJ, Moffitt TE, Olshansky SJ, Perry D, Verdin E, Kuchel GA -
Tolerability and Safety of a Novel Ketogenic Ester, Bis-Hexanoyl (R)-1,3-Butanediol: A Randomized Controlled Trial in Healthy Adults.
Nutrients 2021 Chen O, Blonquist TM, Mah E, Sanoshy K, Beckman D, Nieman KM, Winters BL, Anthony JC, Verdin E, Newman JC, Stubbs BJ -
Complete sequence of an isolate of snake melon asteroid mosaic virus confirms that it is a member of a distinct sobemovirus species.
Archives of virology 2021 Desbiez C, Verdin E, Lecoq H -
NAD+ Repletion Reverses Heart Failure With Preserved Ejection Fraction.
Circulation research 2021 Tong D, Schiattarella GG, Jiang N, Altamirano F, Szweda PA, Elnwasany A, Lee DI, Yoo H, Kass DA, Szweda LI, Lavandero S, Verdin E, Gillette TG, Hill JA -
Modeling Predictive Age-Dependent and Age-Independent Symptoms and Comorbidities of Patients Seeking Treatment for COVID-19: Model Development and Validation Study.
Journal of medical Internet research 2021 Huang Y, Radenkovic D, Perez K, Nadeau K, Verdin E, Furman D -
Genetic Toxicity Studies of the Ketogenic Ester Bis Hexanoyl (R)-1,3-Butanediol.
International journal of toxicology 2021 Stubbs BJ, Nikiforov AI, Rihner MO, Weston S, Higley N, Roy S, Dakoulas E, Verdin E, Newman JC -
Toxicological evaluation of the ketogenic ester bis hexanoyl (R)-1,3-butanediol: Subchronic toxicity in Sprague Dawley rats.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2021 Stubbs BJ, Nikiforov AI, Rihner MO, Weston SL, Higley N, Stump DG, Krane GA, Gadupudi G, Verdin E, Newman JC -
Evaluating a New Class of AKT/mTOR Activators for HIV Latency Reversing Activity Ex Vivo and In Vivo.
Journal of virology 2021 Gramatica A, Schwarzer R, Brantley W, Varco-Merth B, Sperber HS, Hull PA, Montano M, Migueles SA, Rosenthal D, Hogan LE, Johnson JR, Packard TA, Grimmett ZW, Herzig E, Besnard E, Nekorchuk M, Hsiao F,… -
CAGE-seq reveals that HIV-1 latent infection does not trigger unique cellular responses in a Jurkat T cell model.
Journal of virology 2021 Matsui H, Shirakawa K, Konishi Y, Hirabayashi S, Sarca AD, Fukuda H, Nomura R, Stanford E, Horisawa Y, Kazuma Y, Matsumoto T, Yamazaki H, Murakawa Y, Battivelli E, Verdin E, Koyanagi Y, Takaori-Kondo … -
Author Correction: Senescent cells promote tissue NAD+ decline during ageing via the activation of CD38+ macrophages.
Nature metabolism 2021 Covarrubias AJ, Kale A, Perrone R, Lopez-Dominguez JA, Pisco AO, Kasler HG, Schmidt MS, Heckenbach I, Kwok R, Wiley CD, Wong HS, Gibbs E, Iyer SS, Basisty N, Wu Q, Kim IJ, Silva E, Vitangcol K, Shin … -
ARDD 2020: from aging mechanisms to interventions.
Aging 2020 Mkrtchyan GV, Abdelmohsen K, Andreux P, Bagdonaite I, Barzilai N, Brunak S, Cabreiro F, de Cabo R, Campisi J, Cuervo AM, Demaria M, Ewald CY, Fang EF, Faragher R, Ferrucci L, Freund A, Silva-García CG… -
Ketone Ester Treatment Improves Cardiac Function and Reduces Pathologic Remodeling in Preclinical Models of Heart Failure.
Circulation. Heart failure 2020 Yurista SR, Matsuura TR, Silljé HHW, Nijholt KT, McDaid KS, Shewale SV, Leone TC, Newman JC, Verdin E, van Veldhuisen DJ, de Boer RA, Kelly DP, Westenbrink BD -
NAD+ metabolism and its roles in cellular processes during ageing.
Nature reviews. Molecular cell biology 2020 Covarrubias AJ, Perrone R, Grozio A, Verdin E -
Human splice factors contribute to latent HIV infection in primary cell models and blood CD4+ T cells from ART-treated individuals.
PLoS pathogens 2020 Moron-Lopez S, Telwatte S, Sarabia I, Battivelli E, Montano M, Macedo AB, Aran D, Butte AJ, Jones RB, Bosque A, Verdin E, Greene WC, Wong JK, Yukl SA -
SUCLA2 mutations cause global protein succinylation contributing to the pathomechanism of a hereditary mitochondrial disease.
Nature communications 2020 Gut P, Matilainen S, Meyer JG, Pällijeff P, Richard J, Carroll CJ, Euro L, Jackson CB, Isohanni P, Minassian BA, Alkhater RA, Østergaard E, Civiletto G, Parisi A, Thevenet J, Rardin MJ, He W, Nishida … -
In vitro stability and in vivo pharmacokinetics of the novel ketogenic ester, bis hexanoyl (R)-1,3-butanediol.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2020 Stubbs BJ, Blade T, Mills S, Thomas J, Yufei X, Nelson FR, Higley N, Nikiforov AI, Rhiner MO, Verdin E, Newman JC -
Senescent cells promote tissue NAD+ decline during ageing via the activation of CD38+ macrophages.
Nature metabolism 2020 Covarrubias AJ, Kale A, Perrone R, Lopez-Dominguez JA, Pisco AO, Kasler HG, Schmidt MS, Heckenbach I, Kwok R, Wiley CD, Wong HS, Gibbs E, Iyer SS, Basisty N, Wu Q, Kim IJ, Silva E, Vitangcol K, Shin … -
Paolo Sassone-Corsi (1956-2020).
Science (New York, N.Y.) 2020 Verdin E -
Achieving healthy human longevity: A global grand challenge.
Science translational medicine 2020 Dzau VJ, Finkelman EM, Balatbat CA, Verdin EM, Pettigrew RI -
Viral gene drive in herpesviruses.
Nature communications 2020 Walter M, Verdin E -
Clinical Evidence for Targeting NAD Therapeutically.
Pharmaceuticals (Basel, Switzerland) 2020 Radenkovic D, Verdin E -
Sialyl-LewisX Glycoantigen Is Enriched on Cells with Persistent HIV Transcription during Therapy.
Cell reports 2020 Colomb F, Giron LB, Kuri-Cervantes L, Adeniji OS, Ma T, Dweep H, Battivelli E, Verdin E, Palmer CS, Tateno H, Kossenkov AV, Roan NR, Betts MR, Abdel-Mohsen M -
Investigating Ketone Bodies as Immunometabolic Countermeasures against Respiratory Viral Infections.
Med (New York, N.Y.) 2020 Stubbs BJ, Koutnik AP, Goldberg EL, Upadhyay V, Turnbaugh PJ, Verdin E, Newman JC -
Sequence Similarities between Viroids and Human MicroRNAs.
Intervirology 2020 Bengone-Abogourin JG, Chelkha N, Verdin E, Colson P -
FOXO1 promotes HIV latency by suppressing ER stress in T cells.
Nature microbiology 2020 Vallejo-Gracia A, Chen IP, Perrone R, Besnard E, Boehm D, Battivelli E, Tezil T, Krey K, Raymond KA, Hull PA, Walter M, Habrylo I, Cruz A, Deeks S, Pillai S, Verdin E, Ott M -
Distribution and evolution of the major viruses infecting cucurbitaceous and solanaceous crops in the French Mediterranean area.
Virus research 2020 Desbiez C, Wipf-Scheibel C, Millot P, Berthier K, Girardot G, Gognalons P, Hirsch J, Moury B, Nozeran K, Piry S, Schoeny A, Verdin E -
Ketogenic Diets Alter the Gut Microbiome Resulting in Decreased Intestinal Th17 Cells.
Cell 2020 Ang QY, Alexander M, Newman JC, Tian Y, Cai J, Upadhyay V, Turnbaugh JA, Verdin E, Hall KD, Leibel RL, Ravussin E, Rosenbaum M, Patterson AD, Turnbaugh PJ -
A SARS-CoV-2 protein interaction map reveals targets for drug repurposing.
Nature 2020 Gordon DE, Jang GM, Bouhaddou M, Xu J, Obernier K, White KM, O'Meara MJ, Rezelj VV, Guo JZ, Swaney DL, Tummino TA, Hüttenhain R, Kaake RM, Richards AL, Tutuncuoglu B, Foussard H, Batra J, Haas K, … -
Mitochondrial Deacetylase Sirt3 Reduces Vascular Dysfunction and Hypertension While Sirt3 Depletion in Essential Hypertension Is Linked to Vascular Inflammation and Oxidative Stress.
Circulation research 2019 Dikalova AE, Pandey A, Xiao L, Arslanbaeva L, Sidorova T, Lopez MG, Billings FT, Verdin E, Auwerx J, Harrison DG, Dikalov SI -
Chronic inflammation in the etiology of disease across the life span.
Nature medicine 2019 Furman D, Campisi J, Verdin E, Carrera-Bastos P, Targ S, Franceschi C, Ferrucci L, Gilroy DW, Fasano A, Miller GW, Miller AH, Mantovani A, Weyand CM, Barzilai N, Goronzy JJ, Rando TA, Effros RB, Lucia… -
Sixty Years After the First Description: Genome Sequence and Biological Characterization of European Wheat Striate Mosaic Virus Infecting Cereal Crops.
Phytopathology 2019 Sõmera M, Kvarnheden A, Desbiez C, Blystad DR, Sooväli P, Kundu JK, Gantsovski M, Nygren J, Lecoq H, Verdin E, Spetz C, Tamisier L, Truve E, Massart S -
Stable integrant-specific differences in bimodal HIV-1 expression patterns revealed by high-throughput analysis.
PLoS pathogens 2019 Read DF, Atindaana E, Pyaram K, Yang F, Emery S, Cheong A, Nakama KR, Burnett C, Larragoite ET, Battivelli E, Verdin E, Planelles V, Chang CH, Telesnitsky A, Kidd JM -
Lifespan-increasing drug nordihydroguaiaretic acid inhibits p300 and activates autophagy.
NPJ aging and mechanisms of disease 2019 Tezil T, Chamoli M, Ng CP, Simon RP, Butler VJ, Jung M, Andersen J, Kao AW, Verdin E -
From discoveries in ageing research to therapeutics for healthy ageing.
Nature 2019 Campisi J, Kapahi P, Lithgow GJ, Melov S, Newman JC, Verdin E -
High-throughput sequencing of complete genomes of ipomoviruses associated with an epidemic of cassava brown streak disease in the Comoros Archipelago.
Archives of virology 2019 Scussel S, Candresse T, Marais A, Claverie S, Hoareau M, Azali HA, Verdin E, Tepfer M, Filloux D, Fernandez E, Roumagnac P, Robène I, Lefeuvre P, Jourda C, Roux-Cuvelier M, Lett JM -
Regulation of UCP1 and Mitochondrial Metabolism in Brown Adipose Tissue by Reversible Succinylation.
Molecular cell 2019 Wang G, Meyer JG, Cai W, Softic S, Li ME, Verdin E, Newgard C, Schilling B, Kahn CR -
Telomere Dysfunction Induces Sirtuin Repression that Drives Telomere-Dependent Disease.
Cell metabolism 2019 Amano H, Chaudhury A, Rodriguez-Aguayo C, Lu L, Akhanov V, Catic A, Popov YV, Verdin E, Johnson H, Stossi F, Sinclair DA, Nakamaru-Ogiso E, Lopez-Berestein G, Chang JT, Neilson JR, Meeker A, Finegold … -
Virus Detection by High-Throughput Sequencing of Small RNAs: Large-Scale Performance Testing of Sequence Analysis Strategies.
Phytopathology 2019 Massart S, Chiumenti M, De Jonghe K, Glover R, Haegeman A, Koloniuk I, Komínek P, Kreuze J, Kutnjak D, Lotos L, Maclot F, Maliogka V, Maree HJ, Olivier T, Olmos A, Pooggin MM, Reynard JS, Ruiz-García … -
High-Resolution Mass Spectrometry to Identify and Quantify Acetylation Protein Targets.
Methods in molecular biology (Clifton, N.J.) 2019 Schilling B, Meyer JG, Wei L, Ott M, Verdin E -
Temporal dynamics of liver mitochondrial protein acetylation and succinylation and metabolites due to high fat diet and/or excess glucose or fructose.
PloS one 2018 Meyer JG, Softic S, Basisty N, Rardin MJ, Verdin E, Gibson BW, Ilkayeva O, Newgard CB, Kahn CR, Schilling B -
Lavender Decline in France Is Associated with Chronic Infection by Lavender-Specific Strains of "Candidatus Phytoplasma solani".
Applied and environmental microbiology 2018 Sémétey O, Gaudin J, Danet JL, Salar P, Theil S, Fontaine M, Krausz M, Chaisse E, Eveillard S, Verdin E, Foissac X -
HIVGKO: A Tool to Assess HIV-1 Latency Reversal Agents in Human Primary CD4+ T Cells.
Bio-protocol 2018 Battivelli E, Verdin E -
Characterization of the first tenuivirus naturally infecting dicotyledonous plants.
Archives of virology 2018 Lecoq H, Wipf-Scheibel C, Verdin E, Desbiez C -
Impairment of Angiogenesis by Fatty Acid Synthase Inhibition Involves mTOR Malonylation.
Cell metabolism 2018 Bruning U, Morales-Rodriguez F, Kalucka J, Goveia J, Taverna F, Queiroz KCS, Dubois C, Cantelmo AR, Chen R, Loroch S, Timmerman E, Caixeta V, Bloch K, Conradi LC, Treps L, Staes A, Gevaert K, Tee A, … -
Biological and Genetic Characterization of New and Known Necroviruses Causing an Emerging Systemic Necrosis Disease of Corn Salad (Valerianella locusta) in France.
Phytopathology 2018 Verdin E, Marais A, Wipf-Scheibel C, Faure C, Pelletier B, David P, Svanella-Dumas L, Poisblaud C, Lecoq H, Candresse T -
Anti-apoptotic Protein BIRC5 Maintains Survival of HIV-1-Infected CD4+ T Cells.
Immunity 2018 Kuo HH, Ahmad R, Lee GQ, Gao C, Chen HR, Ouyang Z, Szucs MJ, Kim D, Tsibris A, Chun TW, Battivelli E, Verdin E, Rosenberg ES, Carr SA, Yu XG, Lichterfeld M -
Distinct chromatin functional states correlate with HIV latency reactivation in infected primary CD4+ T cells.
eLife 2018 Battivelli E, Dahabieh MS, Abdel-Mohsen M, Svensson JP, Tojal Da Silva I, Cohn LB, Gramatica A, Deeks S, Greene WC, Pillai SK, Verdin E -
Histone Deacetylase 7 mediates tissue-specific autoimmunity via control of innate effector function in invariant Natural Killer T Cells.
eLife 2018 Kasler HG, Lee IS, Lim HW, Verdin E -
NAD+-dependent deacetylase SIRT3 in adipocytes is dispensable for maintaining normal adipose tissue mitochondrial function and whole body metabolism.
American journal of physiology. Endocrinology and metabolism 2018 Porter LC, Franczyk MP, Pietka T, Yamaguchi S, Lin JB, Sasaki Y, Verdin E, Apte RS, Yoshino J -
The Mitochondrial Acylome Emerges: Proteomics, Regulation by Sirtuins, and Metabolic and Disease Implications.
Cell metabolism 2018 Carrico C, Meyer JG, He W, Gibson BW, Verdin E -
Lysine Acetylation Goes Global: From Epigenetics to Metabolism and Therapeutics.
Chemical reviews 2018 Ali I, Conrad RJ, Verdin E, Ott M -
Sirt4 is a mitochondrial regulator of metabolism and lifespan in Drosophila melanogaster.
Proceedings of the National Academy of Sciences of the United States of America 2018 Wood JG, Schwer B, Wickremesinghe PC, Hartnett DA, Burhenn L, Garcia M, Li M, Verdin E, Helfand SL -
Defining Metabolic and Nonmetabolic Regulation of Histone Acetylation by NSAID Chemotypes.
Molecular pharmaceutics 2017 Shrimp JH, Garlick JM, Tezil T, Sorum AW, Worth AJ, Blair IA, Verdin E, Snyder NW, Meier JL -
Metabolic reprogramming of human CD8+ memory T cells through loss of SIRT1.
The Journal of experimental medicine 2017 Jeng MY, Hull PA, Fei M, Kwon HS, Tsou CL, Kasler H, Ng CP, Gordon DE, Johnson J, Krogan N, Verdin E, Ott M -
Distinct Circadian Signatures in Liver and Gut Clocks Revealed by Ketogenic Diet.
Cell metabolism 2017 Tognini P, Murakami M, Liu Y, Eckel-Mahan KL, Newman JC, Verdin E, Baldi P, Sassone-Corsi P -
Ketogenic Diet Reduces Midlife Mortality and Improves Memory in Aging Mice.
Cell metabolism 2017 Newman JC, Covarrubias AJ, Zhao M, Yu X, Gut P, Ng CP, Huang Y, Haldar S, Verdin E -
Sirtuin-3 Promotes Adipogenesis, Osteoclastogenesis, and Bone Loss in Aging Male Mice.
Endocrinology 2017 Ho L, Wang L, Roth TM, Pan Y, Verdin EM, Hsiao EC, Nissenson RA -
β-Hydroxybutyrate: A Signaling Metabolite.
Annual review of nutrition 2017 Newman JC, Verdin E -
Intestinal SIRT3 overexpression in mice improves whole body glucose homeostasis independent of body weight.
Molecular metabolism 2017 Ramachandran D, Clara R, Fedele S, Hu J, Lackzo E, Huang JY, Verdin E, Langhans W, Mansouri A -
New species in the papaya ringspot virus cluster: Insights into the evolution of the PRSV lineage.
Virus research 2017 Desbiez C, Wipf-Scheibel C, Millot P, Verdin E, Dafalla G, Lecoq H -
Kaempferol increases levels of coenzyme Q in kidney cells and serves as a biosynthetic ring precursor.
Free radical biology & medicine 2017 Fernández-Del-Río L, Nag A, Gutiérrez Casado E, Ariza J, Awad AM, Joseph AI, Kwon O, Verdin E, de Cabo R, Schneider C, Torres JZ, Burón MI, Clarke CF, Villalba JM -
Sequencing viral siRNAs to identify previously undescribed viruses and viroids in a panel of ornamental plant samples structured as a matrix of pools.
Virus research 2017 Verdin E, Wipf-Scheibel C, Gognalons P, Aller F, Jacquemond M, Tepfer M -
Tonic LAT-HDAC7 Signals Sustain Nur77 and Irf4 Expression to Tune Naive CD4 T Cells.
Cell reports 2017 Myers DR, Lau T, Markegard E, Lim HW, Kasler H, Zhu M, Barczak A, Huizar JP, Zikherman J, Erle DJ, Zhang W, Verdin E, Roose JP -
Long-term calorie restriction in humans is not associated with indices of delayed immunologic aging: A descriptive study.
Nutrition and healthy aging 2017 Tomiyama AJ, Milush JM, Lin J, Flynn JM, Kapahi P, Verdin E, Sinclair E, Melov S, Epel ES -
The mTOR Complex Controls HIV Latency.
Cell host & microbe 2016 Besnard E, Hakre S, Kampmann M, Lim HW, Hosmane NN, Martin A, Bassik MC, Verschueren E, Battivelli E, Chan J, Svensson JP, Gramatica A, Conrad RJ, Ott M, Greene WC, Krogan NJ, Siliciano RF, Weissman … -
SIRT3 blocks myofibroblast differentiation and pulmonary fibrosis by preventing mitochondrial DNA damage.
American journal of physiology. Lung cellular and molecular physiology 2016 Bindu S, Pillai VB, Kanwal A, Samant S, Mutlu GM, Verdin E, Dulin N, Gupta MP -
Aging Promotes Sirtuin 3-Dependent Cartilage Superoxide Dismutase 2 Acetylation and Osteoarthritis.
Arthritis & rheumatology (Hoboken, N.J.) 2016 Fu Y, Kinter M, Hudson J, Humphries KM, Lane RS, White JR, Hakim M, Pan Y, Verdin E, Griffin TM -
Characterization of a new cucurbit-infecting ipomovirus from Sudan.
Archives of virology 2016 Desbiez C, Verdin E, Tepfer M, Wipf-Scheibel C, Millot P, Dafalla G, Lecoq H -
Salicylate, diflunisal and their metabolites inhibit CBP/p300 and exhibit anticancer activity.
eLife 2016 Shirakawa K, Wang L, Man N, Maksimoska J, Sorum AW, Lim HW, Lee IS, Shimazu T, Newman JC, Schröder S, Ott M, Marmorstein R, Meier J, Nimer S, Verdin E -
LEDGIN-mediated Inhibition of Integrase-LEDGF/p75 Interaction Reduces Reactivation of Residual Latent HIV.
EBioMedicine 2016 Vranckx LS, Demeulemeester J, Saleh S, Boll A, Vansant G, Schrijvers R, Weydert C, Battivelli E, Verdin E, Cereseto A, Christ F, Gijsbers R, Debyser Z -
A genetically novel, narrow-host-range isolate of cucumber mosaic virus (CMV) from rosemary.
Archives of virology 2016 Tepfer M, Girardot G, Fénéant L, Ben Tamarzizt H, Verdin E, Moury B, Jacquemond M -
Characterization and occurrence of squash chlorotic leaf spot virus, a tentative new torradovirus infecting cucurbits in Sudan.
Archives of virology 2016 Lecoq H, Verdin E, Tepfer M, Wipf-Scheibel C, Millot P, Dafalla G, Desbiez C -
A Novel Sirtuin-3 Inhibitor, LC-0296, Inhibits Cell Survival and Proliferation, and Promotes Apoptosis of Head and Neck Cancer Cells.
Anticancer research 2016 Alhazzazi TY, Kamarajan P, Xu Y, Ai T, Chen L, Verdin E, Kapila YL -
SIRT3 Blocks Aging-Associated Tissue Fibrosis in Mice by Deacetylating and Activating Glycogen Synthase Kinase 3β.
Molecular and cellular biology 2015 Sundaresan NR, Bindu S, Pillai VB, Samant S, Pan Y, Huang JY, Gupta M, Nagalingam RS, Wolfgeher D, Verdin E, Gupta MP -
Mitochondrial Dysfunction Induces Senescence with a Distinct Secretory Phenotype.
Cell metabolism 2015 Wiley CD, Velarde MC, Lecot P, Liu S, Sarnoski EA, Freund A, Shirakawa K, Lim HW, Davis SS, Ramanathan A, Gerencser AA, Verdin E, Campisi J -
NAD⁺ in aging, metabolism, and neurodegeneration.
Science (New York, N.Y.) 2015 Verdin E -
Correction: Repressive LTR Nucleosome Positioning by the BAF Complex Is Required for HIV Latency.
PLoS biology 2015 Rafati H, Parra M, Hakre S, Moshkin Y, Verdin E, Mahmoudi T -
Critical role of acetylation in tau-mediated neurodegeneration and cognitive deficits.
Nature medicine 2015 Min SW, Chen X, Tracy TE, Li Y, Zhou Y, Wang C, Shirakawa K, Minami SS, Defensor E, Mok SA, Sohn PD, Schilling B, Cong X, Ellerby L, Gibson BW, Johnson J, Krogan N, Shamloo M, Gestwicki J, Masliah E, … -
HIV Latency Is Established Directly and Early in Both Resting and Activated Primary CD4 T Cells.
PLoS pathogens 2015 Chavez L, Calvanese V, Verdin E -
SIRT5 Regulates both Cytosolic and Mitochondrial Protein Malonylation with Glycolysis as a Major Target.
Molecular cell 2015 Nishida Y, Rardin MJ, Carrico C, He W, Sahu AK, Gut P, Najjar R, Fitch M, Hellerstein M, Gibson BW, Verdin E -
SIRT1 deacetylates RORγt and enhances Th17 cell generation.
The Journal of experimental medicine 2015 Lim HW, Kang SG, Ryu JK, Schilling B, Fei M, Lee IS, Kehasse A, Shirakawa K, Yokoyama M, Schnölzer M, Kasler HG, Kwon HS, Gibson BW, Sato H, Akassoglou K, Xiao C, Littman DR, Ott M, Verdin E -
SIRT1 deacetylates RORγt and enhances Th17 cell generation.
The Journal of experimental medicine 2015 Lim HW, Kang SG, Ryu JK, Schilling B, Fei M, Lee IS, Kehasse A, Shirakawa K, Yokoyama M, Schnölzer M, Kasler HG, Kwon HS, Gibson BW, Sato H, Akassoglou K, Xiao C, Littman DR, Ott M, Verdin E -
MicroRNA-155 Reinforces HIV Latency.
The Journal of biological chemistry 2015 Ruelas DS, Chan JK, Oh E, Heidersbach AJ, Hebbeler AM, Chavez L, Verdin E, Rape M, Greene WC -
SIRT3 and SIRT5 regulate the enzyme activity and cardiolipin binding of very long-chain acyl-CoA dehydrogenase.
PloS one 2015 Zhang Y, Bharathi SS, Rardin MJ, Uppala R, Verdin E, Gibson BW, Goetzman ES -
Understanding HIV latency: the road to an HIV cure.
Annual review of medicine 2015 Dahabieh MS, Battivelli E, Verdin E -
50 years of protein acetylation: from gene regulation to epigenetics, metabolism and beyond.
Nature reviews. Molecular cell biology 2014 Verdin E, Ott M -
Activation of SIRT3 by the NAD⁺ precursor nicotinamide riboside protects from noise-induced hearing loss.
Cell metabolism 2014 Brown KD, Maqsood S, Huang JY, Pan Y, Harkcom W, Li W, Sauve A, Verdin E, Jaffrey SR -
β-hydroxybutyrate: much more than a metabolite.
Diabetes research and clinical practice 2014 Newman JC, Verdin E -
The growing landscape of lysine acetylation links metabolism and cell signalling.
Nature reviews. Molecular cell biology 2014 Choudhary C, Weinert BT, Nishida Y, Verdin E, Mann M -
Adaptation of lettuce mosaic virus to Catharanthus roseus involves mutations in the central domain of the VPg.
Molecular plant-microbe interactions : MPMI 2014 Svanella-Dumas L, Verdin E, Faure C, German-Retana S, Gognalons P, Danet JL, Marais A, Candresse T -
Therapy for latent HIV-1 infection: the role of histone deacetylase inhibitors.
Antiviral chemistry & chemotherapy 2014 Manson McManamy ME, Hakre S, Verdin EM, Margolis DM -
HIV-1 chromatin, transcription, and the regulatory protein Tat.
Methods in molecular biology (Clifton, N.J.) 2014 Colin L, Verdin E, Van Lint C -
The many faces of sirtuins: Coupling of NAD metabolism, sirtuins and lifespan.
Nature medicine 2014 Verdin E -
An in-depth comparison of latent HIV-1 reactivation in multiple cell model systems and resting CD4+ T cells from aviremic patients.
PLoS pathogens 2013 Spina CA, Anderson J, Archin NM, Bosque A, Chan J, Famiglietti M, Greene WC, Kashuba A, Lewin SR, Margolis DM, Mau M, Ruelas D, Saleh S, Shirakawa K, Siliciano RF, Singhania A, Soto PC, Terry VH, … -
SIRT5 regulates the mitochondrial lysine succinylome and metabolic networks.
Cell metabolism 2013 Rardin MJ, He W, Nishida Y, Newman JC, Carrico C, Danielson SR, Guo A, Gut P, Sahu AK, Li B, Uppala R, Fitch M, Riiff T, Zhu L, Zhou J, Mulhern D, Stevens RD, Ilkayeva OR, Newgard CB, Jacobson MP, … -
SIRT4 regulates ATP homeostasis and mediates a retrograde signaling via AMPK.
Aging 2013 Ho L, Titus AS, Banerjee KK, George S, Lin W, Deota S, Saha AK, Nakamura K, Gut P, Verdin E, Kolthur-Seetharam U -
Reactivation of latent HIV-1 in central memory CD4⁺ T cells through TLR-1/2 stimulation.
Retrovirology 2013 Novis CL, Archin NM, Buzon MJ, Verdin E, Round JL, Lichterfeld M, Margolis DM, Planelles V, Bosque A -
The nexus of chromatin regulation and intermediary metabolism.
Nature 2013 Gut P, Verdin E -
Ketone bodies as signaling metabolites.
Trends in endocrinology and metabolism: TEM 2013 Newman JC, Verdin E -
Sirtuin 3 (SIRT3) protein regulates long-chain acyl-CoA dehydrogenase by deacetylating conserved lysines near the active site.
The Journal of biological chemistry 2013 Bharathi SS, Zhang Y, Mohsen AW, Uppala R, Balasubramani M, Schreiber E, Uechi G, Beck ME, Rardin MJ, Vockley J, Verdin E, Gibson BW, Hirschey MD, Goetzman ES -
Dual-color HIV reporters trace a population of latently infected cells and enable their purification.
Virology 2013 Calvanese V, Chavez L, Laurent T, Ding S, Verdin E -
Acetylphosphate: a novel link between lysine acetylation and intermediary metabolism in bacteria.
Molecular cell 2013 Verdin E, Ott M -
Sirt3 regulates metabolic flexibility of skeletal muscle through reversible enzymatic deacetylation.
Diabetes 2013 Jing E, O'Neill BT, Rardin MJ, Kleinridders A, Ilkeyeva OR, Ussar S, Bain JR, Lee KY, Verdin EM, Newgard CB, Gibson BW, Kahn CR -
MicroRNAs of the miR-17∼92 family are critical regulators of T(FH) differentiation.
Nature immunology 2013 Kang SG, Liu WH, Lu P, Jin HY, Lim HW, Shepherd J, Fremgen D, Verdin E, Oldstone MB, Qi H, Teijaro JR, Xiao C -
Three rules for HIV latency: location, location, and location.
Cell host & microbe 2013 Ott M, Verdin E -
Rejuvenating SIRT1 activators.
Cell metabolism 2013 Gut P, Verdin E -
Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways.
Proceedings of the National Academy of Sciences of the United States of America 2013 Rardin MJ, Newman JC, Held JM, Cusack MP, Sorensen DJ, Li B, Schilling B, Mooney SD, Kahn CR, Verdin E, Gibson BW -
Reactivation of latent HIV by histone deacetylase inhibitors.
Trends in microbiology 2013 Shirakawa K, Chavez L, Hakre S, Calvanese V, Verdin E -
Sirtuin-3 (SIRT3) and the Hallmarks of Cancer.
Genes & cancer 2013 Alhazzazi TY, Kamarajan P, Verdin E, Kapila YL -
The sirtuins, oxidative stress and aging: an emerging link.
Aging 2013 Merksamer PI, Liu Y, He W, Hirschey MD, Chen D, Verdin E -
Mitochondrial SIRT4-type proteins in Caenorhabditis elegans and mammals interact with pyruvate carboxylase and other acetylated biotin-dependent carboxylases.
Mitochondrion 2013 Wirth M, Karaca S, Wenzel D, Ho L, Tishkoff D, Lombard DB, Verdin E, Urlaub H, Jedrusik-Bode M, Fischle W -
The longevity of sirtuins.
Cell reports 2012 Sinclair D, Verdin E -
Suppression of oxidative stress by β-hydroxybutyrate, an endogenous histone deacetylase inhibitor.
Science (New York, N.Y.) 2012 Shimazu T, Hirschey MD, Newman J, He W, Shirakawa K, Le Moan N, Grueter CA, Lim H, Saunders LR, Stevens RD, Newgard CB, Farese RV, de Cabo R, Ulrich S, Akassoglou K, Verdin E -
Whole-organism screening for gluconeogenesis identifies activators of fasting metabolism.
Nature chemical biology 2012 Gut P, Baeza-Raja B, Andersson O, Hasenkamp L, Hsiao J, Hesselson D, Akassoglou K, Verdin E, Hirschey MD, Stainier DY -
CNS SIRT3 expression is altered by reactive oxygen species and in Alzheimer's disease.
PloS one 2012 Weir HJ, Murray TK, Kehoe PG, Love S, Verdin EM, O'Neill MJ, Lane JD, Balthasar N -
Nuclear export of histone deacetylase 7 during thymic selection is required for immune self-tolerance.
The EMBO journal 2012 Kasler HG, Lim HW, Mottet D, Collins AM, Lee IS, Verdin E -
Mitochondrial protein acylation and intermediary metabolism: regulation by sirtuins and implications for metabolic disease.
The Journal of biological chemistry 2012 Newman JC, He W, Verdin E -
Inhibitors of the NAD(+)-Dependent Protein Desuccinylase and Demalonylase Sirt5.
ACS medicinal chemistry letters 2012 Maurer B, Rumpf T, Scharfe M, Stolfa DA, Schmitt ML, He W, Verdin E, Sippl W, Jung M -
Inhibition of SIRT2 potentiates the anti-motility activity of taxanes: implications for antineoplastic combination therapies.
Neoplasia (New York, N.Y.) 2012 Bonezzi K, Belotti D, North BJ, Ghilardi C, Borsotti P, Resovi A, Ubezio P, Riva A, Giavazzi R, Verdin E, Taraboletti G -
Metabolic regulation, mitochondria and the life-prolonging effect of rapamycin: a mini-review.
Gerontology 2012 Pan Y, Nishida Y, Wang M, Verdin E -
Mitochondrial sirtuins: regulators of protein acylation and metabolism.
Trends in endocrinology and metabolism: TEM 2012 He W, Newman JC, Wang MZ, Ho L, Verdin E -
Dietary restriction attenuates age-associated muscle atrophy by lowering oxidative stress in mice even in complete absence of CuZnSOD.
Aging cell 2012 Jang YC, Liu Y, Hayworth CR, Bhattacharya A, Lustgarten MS, Muller FL, Chaudhuri A, Qi W, Li Y, Huang JY, Verdin E, Richardson A, Van Remmen H -
Towards an HIV cure: a global scientific strategy.
Nature reviews. Immunology 2012 International AIDS Society Scientific Working Group on HIV Cure, Deeks SG, Autran B, Berkhout B, Benkirane M, Cairns S, Chomont N, Chun TW, Churchill M, Di Mascio M, Katlama C, Lafeuillade A, Landay A… -
Receptor-interacting protein (RIP) and Sirtuin-3 (SIRT3) are on opposite sides of anoikis and tumorigenesis.
Cancer 2012 Kamarajan P, Alhazzazi TY, Danciu T, D'silva NJ, Verdin E, Kapila YL -
Immunosenescence and HIV.
Current opinion in immunology 2012 Deeks SG, Verdin E, McCune JM -
Angiopoietin-1 and vascular endothelial growth factor regulation of leukocyte adhesion to endothelial cells: role of nuclear receptor-77.
Arteriosclerosis, thrombosis, and vascular biology 2012 Ismail H, Mofarrahi M, Echavarria R, Harel S, Verdin E, Lim HW, Jin ZG, Sun J, Zeng H, Hussain SN -
HIV latency: experimental systems and molecular models.
FEMS microbiology reviews 2012 Hakre S, Chavez L, Shirakawa K, Verdin E -
Platform-independent and label-free quantitation of proteomic data using MS1 extracted ion chromatograms in skyline: application to protein acetylation and phosphorylation.
Molecular & cellular proteomics : MCP 2012 Schilling B, Rardin MJ, MacLean BX, Zawadzka AM, Frewen BE, Cusack MP, Sorensen DJ, Bereman MS, Jing E, Wu CC, Verdin E, Kahn CR, Maccoss MJ, Gibson BW -
Mitochondrial acetylome analysis in a mouse model of alcohol-induced liver injury utilizing SIRT3 knockout mice.
Journal of proteome research 2012 Fritz KS, Galligan JJ, Hirschey MD, Verdin E, Petersen DR -
Three novel acetylation sites in the Foxp3 transcription factor regulate the suppressive activity of regulatory T cells.
Journal of immunology (Baltimore, Md. : 1950) 2012 Kwon HS, Lim HW, Wu J, Schnölzer M, Verdin E, Ott M -
HDAC5 is required for maintenance of pericentric heterochromatin, and controls cell-cycle progression and survival of human cancer cells.
Cell death and differentiation 2012 Peixoto P, Castronovo V, Matheus N, Polese C, Peulen O, Gonzalez A, Boxus M, Verdin E, Thiry M, Dequiedt F, Mottet D -
BET bromodomain-targeting compounds reactivate HIV from latency via a Tat-independent mechanism.
Cell cycle (Georgetown, Tex.) 2012 Boehm D, Calvanese V, Dar RD, Xing S, Schroeder S, Martins L, Aull K, Li PC, Planelles V, Bradner JE, Zhou MM, Siliciano RF, Weinberger L, Verdin E, Ott M -
Combination of biological screening in a cellular model of viral latency and virtual screening identifies novel compounds that reactivate HIV-1.
Journal of virology 2012 Gallastegui E, Marshall B, Vidal D, Sanchez-Duffhues G, Collado JA, Alvarez-Fernández C, Luque N, Terme JM, Gatell JM, Sánchez-Palomino S, Muñoz E, Mestres J, Verdin E, Jordan A -
Deficiency of the lipid synthesis enzyme, DGAT1, extends longevity in mice.
Aging 2012 Streeper RS, Grueter CA, Salomonis N, Cases S, Levin MC, Koliwad SK, Zhou P, Hirschey MD, Verdin E, Farese RV -
Viruses of pepper crops in the Mediterranean basin: a remarkable stasis.
Advances in virus research 2012 Moury B, Verdin E -
Repressive LTR nucleosome positioning by the BAF complex is required for HIV latency.
PLoS biology 2011 Rafati H, Parra M, Hakre S, Moshkin Y, Verdin E, Mahmoudi T -
SIRT3 regulates mitochondrial protein acetylation and intermediary metabolism.
Cold Spring Harbor symposia on quantitative biology 2011 Hirschey MD, Shimazu T, Huang JY, Schwer B, Verdin E -
Two-pronged binding with bromodomain-containing protein 4 liberates positive transcription elongation factor b from inactive ribonucleoprotein complexes.
The Journal of biological chemistry 2011 Schröder S, Cho S, Zeng L, Zhang Q, Kaehlcke K, Mak L, Lau J, Bisgrove D, Schnölzer M, Verdin E, Zhou MM, Ott M -
SIRT3 deficiency and mitochondrial protein hyperacetylation accelerate the development of the metabolic syndrome.
Molecular cell 2011 Hirschey MD, Shimazu T, Jing E, Grueter CA, Collins AM, Aouizerat B, Stancáková A, Goetzman E, Lam MM, Schwer B, Stevens RD, Muehlbauer MJ, Kakar S, Bass NM, Kuusisto J, Laakso M, Alt FW, Newgard CB, … -
The first identification of lysine malonylation substrates and its regulatory enzyme.
Molecular & cellular proteomics : MCP 2011 Peng C, Lu Z, Xie Z, Cheng Z, Chen Y, Tan M, Luo H, Zhang Y, He W, Yang K, Zwaans BM, Tishkoff D, Ho L, Lombard D, He TC, Dai J, Verdin E, Ye Y, Zhao Y -
Sirtuin-3 (Sirt3) regulates skeletal muscle metabolism and insulin signaling via altered mitochondrial oxidation and reactive oxygen species production.
Proceedings of the National Academy of Sciences of the United States of America 2011 Jing E, Emanuelli B, Hirschey MD, Boucher J, Lee KY, Lombard D, Verdin EM, Kahn CR -
SIRT1 and SIRT3 deacetylate homologous substrates: AceCS1,2 and HMGCS1,2.
Aging 2011 Hirschey MD, Shimazu T, Capra JA, Pollard KS, Verdin E -
SIRT3 and cancer: tumor promoter or suppressor?
Biochimica et biophysica acta 2011 Alhazzazi TY, Kamarajan P, Verdin E, Kapila YL -
Histone deacetylase 7 regulates cell survival and TCR signaling in CD4/CD8 double-positive thymocytes.
Journal of immunology (Baltimore, Md. : 1950) 2011 Kasler HG, Young BD, Mottet D, Lim HW, Collins AM, Olson EN, Verdin E -
Epigenetic regulation of HIV latency.
Current opinion in HIV and AIDS 2011 Hakre S, Chavez L, Shirakawa K, Verdin E -
Evolution and structure of Tomato spotted wilt virus populations: evidence of extensive reassortment and insights into emergence processes.
The Journal of general virology 2010 Tentchev D, Verdin E, Marchal C, Jacquet M, Aguilar JM, Moury B -
Calorie restriction reduces oxidative stress by SIRT3-mediated SOD2 activation.
Cell metabolism 2010 Qiu X, Brown K, Hirschey MD, Verdin E, Chen D -
SIRT3 deacetylates mitochondrial 3-hydroxy-3-methylglutaryl CoA synthase 2 and regulates ketone body production.
Cell metabolism 2010 Shimazu T, Hirschey MD, Hua L, Dittenhafer-Reed KE, Schwer B, Lombard DB, Li Y, Bunkenborg J, Alt FW, Denu JM, Jacobson MP, Verdin E -
Sirtuin-3 (SIRT3), a novel potential therapeutic target for oral cancer.
Cancer 2010 Alhazzazi TY, Kamarajan P, Joo N, Huang JY, Verdin E, D'Silva NJ, Kapila YL -
Sirtuin regulation of mitochondria: energy production, apoptosis, and signaling.
Trends in biochemical sciences 2010 Verdin E, Hirschey MD, Finley LW, Haigis MC -
Dietary restriction: standing up for sirtuins.
Science (New York, N.Y.) 2010 Baur JA, Chen D, Chini EN, Chua K, Cohen HY, de Cabo R, Deng C, Dimmeler S, Gius D, Guarente LP, Helfand SL, Imai S, Itoh H, Kadowaki T, Koya D, Leeuwenburgh C, McBurney M, Nabeshima Y, Neri C, … -
Zmynd15 encodes a histone deacetylase-dependent transcriptional repressor essential for spermiogenesis and male fertility.
The Journal of biological chemistry 2010 Yan W, Si Y, Slaymaker S, Li J, Zheng H, Young DL, Aslanian A, Saunders L, Verdin E, Charo IF -
HIV persistence and the prospect of long-term drug-free remissions for HIV-infected individuals.
Science (New York, N.Y.) 2010 Trono D, Van Lint C, Rouzioux C, Verdin E, Barré-Sinoussi F, Chun TW, Chomont N -
miRNAs regulate SIRT1 expression during mouse embryonic stem cell differentiation and in adult mouse tissues.
Aging 2010 Saunders LR, Sharma AD, Tawney J, Nakagawa M, Okita K, Yamanaka S, Willenbring H, Verdin E -
In vivo, in vitro, and in silico analysis of methylation of the HIV-1 provirus.
Methods (San Diego, Calif.) 2010 Chávez L, Kauder S, Verdin E -
HAT trick: p300, small molecule, inhibitor.
Chemistry & biology 2010 Ott M, Verdin E -
Acetate metabolism and aging: An emerging connection.
Mechanisms of ageing and development 2010 Shimazu T, Hirschey MD, Huang JY, Ho LT, Verdin E -
Regulatory signal transduction pathways for class IIa histone deacetylases.
Current opinion in pharmacology 2010 Parra M, Verdin E -
Partial chromosome sequence of Spiroplasma citri reveals extensive viral invasion and important gene decay.
Applied and environmental microbiology 2010 Carle P, Saillard C, Carrère N, Carrère S, Duret S, Eveillard S, Gaurivaud P, Gourgues G, Gouzy J, Salar P, Verdin E, Breton M, Blanchard A, Laigret F, Bové JM, Renaudin J, Foissac X -
Impact papers on aging in 2009.
Aging 2010 Blagosklonny MV, Campisi J, Sinclair DA, Bartke A, Blasco MA, Bonner WM, Bohr VA, Brosh RM, Brunet A, Depinho RA, Donehower LA, Finch CE, Finkel T, Gorospe M, Gudkov AV, Hall MN, Hekimi S, Helfand SL,… -
The Cellular lysine methyltransferase Set7/9-KMT7 binds HIV-1 TAR RNA, monomethylates the viral transactivator Tat, and enhances HIV transcription.
Cell host & microbe 2010 Pagans S, Kauder SE, Kaehlcke K, Sakane N, Schroeder S, Dormeyer W, Trievel RC, Verdin E, Schnolzer M, Ott M -
SIRT3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation.
Nature 2010 Hirschey MD, Shimazu T, Goetzman E, Jing E, Schwer B, Lombard DB, Grueter CA, Harris C, Biddinger S, Ilkayeva OR, Stevens RD, Li Y, Saha AK, Ruderman NB, Bain JR, Newgard CB, Farese RV, Alt FW, Kahn … -
Mitochondrial sirtuins.
Biochimica et biophysica acta 2010 Huang JY, Hirschey MD, Shimazu T, Ho L, Verdin E -
First Report of Tomato torrado virus in Tomato Crops in France.
Plant disease 2009 Verdin E, Gognalons P, Wipf-Scheibel C, Bornard I, Ridray G, Schoen L, Lecoq H -
Histone deacetylase 7 and FoxA1 in estrogen-mediated repression of RPRM.
Molecular and cellular biology 2009 Malik S, Jiang S, Garee JP, Verdin E, Lee AV, O'Malley BW, Zhang M, Belaguli NS, Oesterreich S -
CpG methylation controls reactivation of HIV from latency.
PLoS pathogens 2009 Blazkova J, Trejbalova K, Gondois-Rey F, Halfon P, Philibert P, Guiguen A, Verdin E, Olive D, Van Lint C, Hejnar J, Hirsch I -
Epigenetic regulation of HIV-1 latency by cytosine methylation.
PLoS pathogens 2009 Kauder SE, Bosque A, Lindqvist A, Planelles V, Verdin E -
A new splice variant of the mouse SIRT3 gene encodes the mitochondrial precursor protein.
PloS one 2009 Cooper HM, Huang JY, Verdin E, Spelbrink JN -
Cell biology. Stress response and aging.
Science (New York, N.Y.) 2009 Saunders LR, Verdin E -
The serum response factor and a putative novel transcription factor regulate expression of the immediate-early gene Arc/Arg3.1 in neurons.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2009 Pintchovski SA, Peebles CL, Kim HJ, Verdin E, Finkbeiner S -
Pyridylalanine-containing hydroxamic acids as selective HDAC6 inhibitors.
ChemMedChem 2009 Schäfer S, Saunders L, Schlimme S, Valkov V, Wagner JM, Kratz F, Sippl W, Verdin E, Jung M -
Acetylation of mitochondrial proteins.
Methods in enzymology 2009 Hirschey MD, Shimazu T, Huang JY, Verdin E -
Thiobarbiturates as sirtuin inhibitors: virtual screening, free-energy calculations, and biological testing.
ChemMedChem 2008 Uciechowska U, Schemies J, Neugebauer RC, Huda EM, Schmitt ML, Meier R, Verdin E, Jung M, Sippl W -
HDAC4 represses p21(WAF1/Cip1) expression in human cancer cells through a Sp1-dependent, p53-independent mechanism.
Oncogene 2008 Mottet D, Pirotte S, Lamour V, Hagedorn M, Javerzat S, Bikfalvi A, Bellahcène A, Verdin E, Castronovo V -
Destabilization of ERBB2 transcripts by targeting 3' untranslated region messenger RNA associated HuR and histone deacetylase-6.
Molecular cancer research : MCR 2008 Scott GK, Marx C, Berger CE, Saunders LR, Verdin E, Schäfer S, Jung M, Benz CC -
Control of endothelial cell proliferation and migration by VEGF signaling to histone deacetylase 7.
Proceedings of the National Academy of Sciences of the United States of America 2008 Wang S, Li X, Parra M, Verdin E, Bassel-Duby R, Olson EN -
Structure-activity studies on splitomicin derivatives as sirtuin inhibitors and computational prediction of binding mode.
Journal of medicinal chemistry 2008 Neugebauer RC, Uchiechowska U, Meier R, Hruby H, Valkov V, Verdin E, Sippl W, Jung M -
Conserved metabolic regulatory functions of sirtuins.
Cell metabolism 2008 Schwer B, Verdin E -
Regulation of human immunodeficiency virus-1 latency and its reactivation.
Bulletin et memoires de l'Academie royale de medecine de Belgique 2008 Verdin E -
AROuSing SIRT1: identification of a novel endogenous SIRT1 activator.
Molecular cell 2007 Verdin E -
Phenylalanine-containing hydroxamic acids as selective inhibitors of class IIb histone deacetylases (HDACs).
Bioorganic & medicinal chemistry 2007 Schäfer S, Saunders L, Eliseeva E, Velena A, Jung M, Schwienhorst A, Strasser A, Dickmanns A, Ficner R, Schlimme S, Sippl W, Verdin E, Jung M -
Mammalian Sir2 homolog SIRT3 regulates global mitochondrial lysine acetylation.
Molecular and cellular biology 2007 Lombard DB, Alt FW, Cheng HL, Bunkenborg J, Streeper RS, Mostoslavsky R, Kim J, Yancopoulos G, Valenzuela D, Murphy A, Yang Y, Chen Y, Hirschey MD, Bronson RT, Haigis M, Guarente LP, Farese RV, … -
Interphase nucleo-cytoplasmic shuttling and localization of SIRT2 during mitosis.
PloS one 2007 North BJ, Verdin E -
Regulation of insulin secretion by SIRT4, a mitochondrial ADP-ribosyltransferase.
The Journal of biological chemistry 2007 Ahuja N, Schwer B, Carobbio S, Waltregny D, North BJ, Castronovo V, Maechler P, Verdin E -
Sirtuins: critical regulators at the crossroads between cancer and aging.
Oncogene 2007 Saunders LR, Verdin E -
Conserved P-TEFb-interacting domain of BRD4 inhibits HIV transcription.
Proceedings of the National Academy of Sciences of the United States of America 2007 Bisgrove DA, Mahmoudi T, Henklein P, Verdin E -
Breast cancer associated transcriptional repressor PLU-1/JARID1B interacts directly with histone deacetylases.
International journal of cancer 2007 Barrett A, Santangelo S, Tan K, Catchpole S, Roberts K, Spencer-Dene B, Hall D, Scibetta A, Burchell J, Verdin E, Freemont P, Taylor-Papadimitriou J -
Mitotic regulation of SIRT2 by cyclin-dependent kinase 1-dependent phosphorylation.
The Journal of biological chemistry 2007 North BJ, Verdin E -
Histone deacetylase 7 functions as a key regulator of genes involved in both positive and negative selection of thymocytes.
Molecular and cellular biology 2007 Kasler HG, Verdin E -
A novel corepressor, BCoR-L1, represses transcription through an interaction with CtBP.
The Journal of biological chemistry 2007 Pagan JK, Arnold J, Hanchard KJ, Kumar R, Bruno T, Jones MJ, Richard DJ, Forrest A, Spurdle A, Verdin E, Crossley M, Fanciulli M, Chenevix-Trench G, Young DB, Khanna KK -
Myosin phosphatase dephosphorylates HDAC7, controls its nucleocytoplasmic shuttling, and inhibits apoptosis in thymocytes.
Genes & development 2007 Parra M, Mahmoudi T, Verdin E -
First Report of the Presence of Tomato apical stunt viroid on Tomato in Sénégal.
Plant disease 2007 Candresse T, Marais A, Ollivier F, Verdin E, Blancard D -
Design and evaluation of 'Linkerless' hydroxamic acids as selective HDAC8 inhibitors.
Bioorganic & medicinal chemistry letters 2007 Krennhrubec K, Marshall BL, Hedglin M, Verdin E, Ulrich SM -
Knockdown of XAB2 enhances all-trans retinoic acid-induced cellular differentiation in all-trans retinoic acid-sensitive and -resistant cancer cells.
Cancer research 2007 Ohnuma-Ishikawa K, Morio T, Yamada T, Sugawara Y, Ono M, Nagasawa M, Yasuda A, Morimoto C, Ohnuma K, Dang NH, Hosoi H, Verdin E, Mizutani S -
Adenosine mimetics as inhibitors of NAD+-dependent histone deacetylases, from kinase to sirtuin inhibition.
Journal of medicinal chemistry 2006 Trapp J, Jochum A, Meier R, Saunders L, Marshall B, Kunick C, Verdin E, Goekjian P, Sippl W, Jung M -
Ornithine decarboxylase activity in tumor cell lines correlates with sensitivity to cell death induced by histone deacetylase inhibitors.
Molecular cancer therapeutics 2006 Saunders LR, Verdin E -
Reversible lysine acetylation controls the activity of the mitochondrial enzyme acetyl-CoA synthetase 2.
Proceedings of the National Academy of Sciences of the United States of America 2006 Schwer B, Bunkenborg J, Verdin RO, Andersen JS, Verdin E -
The SWI/SNF chromatin-remodeling complex is a cofactor for Tat transactivation of the HIV promoter.
The Journal of biological chemistry 2006 Mahmoudi T, Parra M, Vries RG, Kauder SE, Verrijzer CP, Ott M, Verdin E -
Detection and characterization of tobacco mild green mosaic virus (TMGMV) large type isolate from trailing petunia in France.
Communications in agricultural and applied biological sciences 2006 Parrella G, Verdin E, Gognalons P, Marchoux G -
The flavoring agent dihydrocoumarin reverses epigenetic silencing and inhibits sirtuin deacetylases.
PLoS genetics 2005 Olaharski AJ, Rine J, Marshall BL, Babiarz J, Zhang L, Verdin E, Smith MT -
NF-kappaB p50 promotes HIV latency through HDAC recruitment and repression of transcriptional initiation.
The EMBO journal 2005 Williams SA, Chen LF, Kwon H, Ruiz-Jarabo CM, Verdin E, Greene WC -
Molecular mechanisms of HIV-1 proviral latency.
Expert review of anti-infective therapy 2005 Bisgrove D, Lewinski M, Bushman F, Verdin E -
Preparation of enzymatically active recombinant class III protein deacetylases.
Methods (San Diego, Calif.) 2005 North BJ, Schwer B, Ahuja N, Marshall B, Verdin E -
Effect of inhibitors of histone deacetylase on the induction of cell differentiation in murine and human erythroleukemia cell lines.
Anti-cancer drugs 2005 Wittich S, Scherf H, Xie C, Heltweg B, Dequiedt F, Verdin E, Gerhäuser C, Jung M -
Genome-wide analysis of chromosomal features repressing human immunodeficiency virus transcription.
Journal of virology 2005 Lewinski MK, Bisgrove D, Shinn P, Chen H, Hoffmann C, Hannenhalli S, Verdin E, Berry CC, Ecker JR, Bushman FD -
Tissue-resident macrophages are productively infected ex vivo by primary X4 isolates of human immunodeficiency virus type 1.
Journal of virology 2005 Jayakumar P, Berger I, Autschbach F, Weinstein M, Funke B, Verdin E, Goldsmith MA, Keppler OT -
Histone deacetylase HDAC8 associates with smooth muscle alpha-actin and is essential for smooth muscle cell contractility.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2005 Waltregny D, Glénisson W, Tran SL, North BJ, Verdin E, Colige A, Castronovo V -
SIRT1 regulates HIV transcription via Tat deacetylation.
PLoS biology 2005 Pagans S, Pedal A, North BJ, Kaehlcke K, Marshall BL, Dorr A, Hetzer-Egger C, Henklein P, Frye R, McBurney MW, Hruby H, Jung M, Verdin E, Ott M -
Protein kinase D1 phosphorylates HDAC7 and induces its nuclear export after T-cell receptor activation.
The Journal of biological chemistry 2004 Parra M, Kasler H, McKinsey TA, Olson EN, Verdin E -
Subtype selective substrates for histone deacetylases.
Journal of medicinal chemistry 2004 Heltweg B, Dequiedt F, Marshall BL, Brauch C, Yoshida M, Nishino N, Verdin E, Jung M -
Expression of histone deacetylase 8, a class I histone deacetylase, is restricted to cells showing smooth muscle differentiation in normal human tissues.
The American journal of pathology 2004 Waltregny D, De Leval L, Glénisson W, Ly Tran S, North BJ, Bellahcène A, Weidle U, Verdin E, Castronovo V -
Prostratin antagonizes HIV latency by activating NF-kappaB.
The Journal of biological chemistry 2004 Williams SA, Chen LF, Kwon H, Fenard D, Bisgrove D, Verdin E, Greene WC -
Screening of histone deacetylases (HDAC) expression in human prostate cancer reveals distinct class I HDAC profiles between epithelial and stromal cells.
European journal of histochemistry : EJH 2004 Waltregny D, North B, Van Mellaert F, de Leval J, Verdin E, Castronovo V -
Sirtuins: Sir2-related NAD-dependent protein deacetylases.
Genome biology 2004 North BJ, Verdin E -
HDAC7 regulates apoptosis in developing thymocytes.
Novartis Foundation symposium 2004 Verdin E, Dequiedt F, Kasler H -
Measurement of mammalian histone deacetylase activity.
Methods in enzymology 2004 Verdin E, Dequiedt F, Fischle W, Frye R, Marshall B, North B -
Tat acetylation: a regulatory switch between early and late phases in HIV transcription elongation.
Novartis Foundation symposium 2004 Ott M, Dorr A, Hetzer-Egger C, Kaehlcke K, Schnolzer M, Henklein P, Cole P, Zhou MM, Verdin E -
Nonisotopic substrate for assaying both human zinc and NAD+-dependent histone deacetylases.
Analytical biochemistry 2003 Heltweg B, Dequiedt F, Verdin E, Jung M -
Acetylation of Tat defines a cyclinT1-independent step in HIV transactivation.
Molecular cell 2003 Kaehlcke K, Dorr A, Hetzer-Egger C, Kiermer V, Henklein P, Schnoelzer M, Loret E, Cole PA, Verdin E, Ott M -
"Candidatus Phlomobacter fragariae" Is the Prevalent Agent of Marginal Chlorosis of Strawberry in French Production Fields and Is Transmitted by the Planthopper Cixius wagneri (China).
Phytopathology 2003 Danet JL, Foissac X, Zreik L, Salar P, Verdin E, Nourrisseau JG, Garnier M -
'Candidatus phytoplasma phoenicium' sp. nov., a novel phytoplasma associated with an emerging lethal disease of almond trees in Lebanon and Iran.
International journal of systematic and evolutionary microbiology 2003 Verdin E, Salar P, Danet JL, Choueiri E, Jreijiri F, El Zammar S, Gélie B, Bové JM, Garnier M -
Class II histone deacetylases: versatile regulators.
Trends in genetics : TIG 2003 Verdin E, Dequiedt F, Kasler HG -
HDAC7, a thymus-specific class II histone deacetylase, regulates Nur77 transcription and TCR-mediated apoptosis.
Immunity 2003 Dequiedt F, Kasler H, Fischle W, Kiermer V, Weinstein M, Herndier BG, Verdin E -
HIV reproducibly establishes a latent infection after acute infection of T cells in vitro.
The EMBO journal 2003 Jordan A, Bisgrove D, Verdin E -
Transcriptional suppression of in vitro-integrated human immunodeficiency virus type 1 does not correlate with proviral DNA methylation.
Journal of virology 2003 Pion M, Jordan A, Biancotto A, Dequiedt F, Gondois-Rey F, Rondeau S, Vigne R, Hejnar J, Verdin E, Hirsch I -
The human Sir2 ortholog, SIRT2, is an NAD+-dependent tubulin deacetylase.
Molecular cell 2003 North BJ, Marshall BL, Borra MT, Denu JM, Verdin E -
The human silent information regulator (Sir)2 homologue hSIRT3 is a mitochondrial nicotinamide adenine dinucleotide-dependent deacetylase.
The Journal of cell biology 2002 Schwer B, North BJ, Frye RA, Ott M, Verdin E -
Transcriptional synergy between Tat and PCAF is dependent on the binding of acetylated Tat to the PCAF bromodomain.
The EMBO journal 2002 Dorr A, Kiermer V, Pedal A, Rackwitz HR, Henklein P, Schubert U, Zhou MM, Verdin E, Ott M -
First Report of Grapevine "Bois Noir" Disease and a New Phytoplasma Infecting Solanaceous Plants in Lebanon.
Plant disease 2002 Choueiri E, Jreijiri F, El Zammar S, Verdin E, Salar P, Danet JL, Bové J, Garnier M -
Control of cytomegalovirus lytic gene expression by histone acetylation.
The EMBO journal 2002 Murphy JC, Fischle W, Verdin E, Sinclair JH -
Structural basis of lysine-acetylated HIV-1 Tat recognition by PCAF bromodomain.
Molecular cell 2002 Mujtaba S, He Y, Zeng L, Farooq A, Carlson JE, Ott M, Verdin E, Zhou MM -
Conserved enzymatic production and biological effect of O-acetyl-ADP-ribose by silent information regulator 2-like NAD+-dependent deacetylases.
The Journal of biological chemistry 2002 Borra MT, O'Neill FJ, Jackson MD, Marshall B, Verdin E, Foltz KR, Denu JM -
Enzymatic activity associated with class II HDACs is dependent on a multiprotein complex containing HDAC3 and SMRT/N-CoR.
Molecular cell 2002 Fischle W, Dequiedt F, Hendzel MJ, Guenther MG, Lazar MA, Voelter W, Verdin E -
Duration of nuclear NF-kappaB action regulated by reversible acetylation.
Science (New York, N.Y.) 2001 Fischle W, Verdin E, Greene WC -
Human HDAC7 histone deacetylase activity is associated with HDAC3 in vivo.
The Journal of biological chemistry 2001 Fischle W, Dequiedt F, Fillion M, Hendzel MJ, Voelter W, Verdin E -
First Report of a Phytoplasma Disease of Almond (Prunus amygdalus) in Lebanon.
Plant disease 2001 Choueiri E, Jreijiri F, Issa S, Verdin E, Bové J, Garnier M -
The site of HIV-1 integration in the human genome determines basal transcriptional activity and response to Tat transactivation.
The EMBO journal 2001 Jordan A, Defechereux P, Verdin E -
[Egg-cell complex, molecular embryology, human genome, then, human proteome].
Revue medicale de Liege 2001 Geenen V, Verdin E -
The emerging role of class II histone deacetylases.
Biochemistry and cell biology = Biochimie et biologie cellulaire 2001 Fischle W, Kiermer V, Dequiedt F, Verdin E -
Use of an internal control in a nested-PCR assay for Mycoplasma hyopneumoniae detection and quantification in tracheobronchiolar washings from pigs.
Molecular and cellular probes 2000 Verdin E, Kobisch M, Bové JM, Garnier M, Saillard C -
A nested PCR assay for the detection of Mycoplasma hyopneumoniae in tracheobronchiolar washings from pigs.
Veterinary microbiology 2000 Verdin E, Saillard C, Labbé A, Bové JM, Kobisch M -
Fructose operon mutants of Spiroplasma citri.
Microbiology (Reading, England) 2000 Gaurivaud P, Laigret F, Verdin E, Garnier M, Bové JM -
BCoR, a novel corepressor involved in BCL-6 repression.
Genes & development 2000 Huynh KD, Fischle W, Verdin E, Bardwell VJ -
Reduced mobility of the alternate splicing factor (ASF) through the nucleoplasm and steady state speckle compartments.
The Journal of cell biology 2000 Kruhlak MJ, Lever MA, Fischle W, Verdin E, Bazett-Jones DP, Hendzel MJ -
A core SMRT corepressor complex containing HDAC3 and TBL1, a WD40-repeat protein linked to deafness.
Genes & development 2000 Guenther MG, Lane WS, Fischle W, Verdin E, Lazar MA, Shiekhattar R -
The Nef protein of HIV-1 associates with rafts and primes T cells for activation.
Proceedings of the National Academy of Sciences of the United States of America 2000 Wang JK, Kiyokawa E, Verdin E, Trono D -
Acetylation of the HIV-1 Tat protein by p300 is important for its transcriptional activity.
Current biology : CB 1999 Ott M, Schnölzer M, Garnica J, Fischle W, Emiliani S, Rackwitz HR, Verdin E -
Cloning and characterization of the murine histone deacetylase (HDAC3).
Biochemical and biophysical research communications 1999 Mahlknecht U, Hoelzer D, Bucala R, Verdin E -
Isoquinolinesulphonamide derivatives inhibit transcriptional elongation of human immunodeficiency virus type 1 RNA in a promyelocytic model of latency.
Antiviral chemistry & chemotherapy 1999 Critchfield JW, Ho O, Roberts BD, Van Lint C, Verdin E, Butera ST -
A new family of human histone deacetylases related to Saccharomyces cerevisiae HDA1p.
The Journal of biological chemistry 1999 Fischle W, Emiliani S, Hendzel MJ, Nagase T, Nomura N, Voelter W, Verdin E -
Genomic organization and chromosomal localization of the human histone deacetylase 3 gene.
Genomics 1999 Mahlknecht U, Emiliani S, Najfeld V, Young S, Verdin E -
Assignment of the histone deacetylase gene (Hdac3) to mouse chromosome 18B3 by in situ hybridization.
Cytogenetics and cell genetics 1999 Mahlknecht U, Bucala R, Verdin E -
High resolution physical mapping of human HDAC3, a potential tumor suppressor gene in the 5q31 region.
Cytogenetics and cell genetics 1999 Mahlknecht U, Bucala R, Hoelzer D, Verdin E -
Apoptosis of CD8+ T cells is mediated by macrophages through interaction of HIV gp120 with chemokine receptor CXCR4.
Nature 1998 Herbein G, Mahlknecht U, Batliwalla F, Gregersen P, Pappas T, Butler J, O'Brien WA, Verdin E -
An interferon regulatory factor binding site in the U5 region of the bovine leukemia virus long terminal repeat stimulates Tax-independent gene expression.
Journal of virology 1998 Kiermer V, Van Lint C, Briclet D, Vanhulle C, Kettmann R, Verdin E, Burny A, Droogmans L -
A class of hybrid polar inducers of transformed cell differentiation inhibits histone deacetylases.
Proceedings of the National Academy of Sciences of the United States of America 1998 Richon VM, Emiliani S, Verdin E, Webb Y, Breslow R, Rifkind RA, Marks PA -
Characterization of a human RPD3 ortholog, HDAC3.
Proceedings of the National Academy of Sciences of the United States of America 1998 Emiliani S, Fischle W, Van Lint C, Al-Abed Y, Verdin E -
Superinduction of IL-8 in T cells by HIV-1 Tat protein is mediated through NF-kappaB factors.
Journal of immunology (Baltimore, Md. : 1950) 1998 Ott M, Lovett JL, Mueller L, Verdin E -
Mutations in the tat gene are responsible for human immunodeficiency virus type 1 postintegration latency in the U1 cell line.
Journal of virology 1998 Emiliani S, Fischle W, Ott M, Van Lint C, Amella CA, Verdin E -
Distinct mechanisms trigger apoptosis in human immunodeficiency virus type 1-infected and in uninfected bystander T lymphocytes.
Journal of virology 1998 Herbein G, Van Lint C, Lovett JL, Verdin E -
Histone acetyltransferases regulate HIV-1 enhancer activity in vitro.
Genes & development 1997 Sheridan PL, Mayall TP, Verdin E, Jones KA -
Transcription factor binding sites downstream of the human immunodeficiency virus type 1 transcription start site are important for virus infectivity.
Journal of virology 1997 Van Lint C, Amella CA, Emiliani S, John M, Jie T, Verdin E -
Immune hyperactivation of HIV-1-infected T cells mediated by Tat and the CD28 pathway.
Science (New York, N.Y.) 1997 Ott M, Emiliani S, Van Lint C, Herbein G, Lovett J, Chirmule N, McCloskey T, Pahwa S, Verdin E -
Dual role of HIV Tat in regulation of apoptosis in T cells.
Journal of immunology (Baltimore, Md. : 1950) 1997 McCloskey TW, Ott M, Tribble E, Khan SA, Teichberg S, Paul MO, Pahwa S, Verdin E, Chirmule N -
A point mutation in the HIV-1 Tat responsive element is associated with postintegration latency.
Proceedings of the National Academy of Sciences of the United States of America 1996 Emiliani S, Van Lint C, Fischle W, Paras P, Ott M, Brady J, Verdin E -
Transcriptional activation and chromatin remodeling of the HIV-1 promoter in response to histone acetylation.
The EMBO journal 1996 Van Lint C, Emiliani S, Ott M, Verdin E -
The expression of a small fraction of cellular genes is changed in response to histone hyperacetylation.
Gene expression 1996 Van Lint C, Emiliani S, Verdin E -
Integrative and free Spiroplasma citri oriC plasmids: expression of the Spiroplasma phoeniceum spiralin in Spiroplasma citri.
Journal of bacteriology 1995 Renaudin J, Marais A, Verdin E, Duret S, Foissac X, Laigret F, Bové JM -
Internal transcriptional regulatory elements in HIV-1 and other retroviruses.
Cellular and molecular biology (Noisy-le-Grand, France) 1995 Verdin E, Van Lint C -
Protein-DNA interactions within DNase I-hypersensitive sites located downstream of the HIV-1 promoter.
The Journal of biological chemistry 1994 el Kharroubi A, Verdin E -
A transcriptional regulatory element is associated with a nuclease-hypersensitive site in the pol gene of human immunodeficiency virus type 1.
Journal of virology 1994 Van Lint C, Ghysdael J, Paras P, Burny A, Verdin E -
Chromatin disruption in the promoter of human immunodeficiency virus type 1 during transcriptional activation.
The EMBO journal 1993 Verdin E, Paras P, Van Lint C -
The restricted nature of HIV-1 tropism for cultured neural cells.
Virology 1992 Sharpless N, Gilbert D, Vandercam B, Zhou JM, Verdin E, Ronnett G, Friedman E, Dubois-Dalcq M -
Human immunodeficiency virus type 1 tropism for brain microglial cells is determined by a region of the env glycoprotein that also controls macrophage tropism.
Journal of virology 1992 Sharpless NE, O'Brien WA, Verdin E, Kufta CV, Chen IS, Dubois-Dalcq M -
DNase I-hypersensitive sites are associated with both long terminal repeats and with the intragenic enhancer of integrated human immunodeficiency virus type 1.
Journal of virology 1991 Verdin E -
Infection of a polarized epithelial cell line with wild-type reovirus leads to virus persistence and altered cellular function.
The Journal of general virology 1991 Montgomery LB, Kao CY, Verdin E, Cahill C, Maratos-Flier E -
The intragenic enhancer of human immunodeficiency virus type 1 contains functional AP-1 binding sites.
Journal of virology 1991 Van Lint C, Burny A, Verdin E -
[Forced eruption, a clinical procedure: apropos of 2 clinical cases].
L' Information dentaire 1990 Verdin E, Deveaux E, Deveaux B -
Identification and characterization of an enhancer in the coding region of the genome of human immunodeficiency virus type 1.
Proceedings of the National Academy of Sciences of the United States of America 1990 Verdin E, Becker N, Bex F, Droogmans L, Burny A -
The GAG precursor of simian immunodeficiency virus assembles into virus-like particles.
The EMBO journal 1989 Delchambre M, Gheysen D, Thines D, Thiriart C, Jacobs E, Verdin E, Horth M, Burny A, Bex F -
Characterization of a common high-affinity receptor for reovirus serotypes 1 and 3 on endothelial cells.
Journal of virology 1989 Verdin EM, King GL, Maratos-Flier E -
Uptake of reovirus serotype 1 by the lungs from the bloodstream is mediated by the viral hemagglutinin.
Journal of virology 1988 Verdin EM, Lynn SP, Fields BN, Maratos-Flier E -
Human immunodeficiency virus cell entry: new insights into the fusion mechanism.
Journal of acquired immune deficiency syndromes 1988 Burny A, Bex F, Brasseur R, Khim MC, Delchambre M, Horth M, Verdin E -
Receptor-mediated vectorial transcytosis of epidermal growth factor by Madin-Darby canine kidney cells.
The Journal of cell biology 1987 Maratos-Flier E, Kao CY, Verdin EM, King GL -
Visualization of viral clearance in the living animal.
Science (New York, N.Y.) 1987 Verdin EM, Maratos-Flier E, Kahn CR, Sodoyez JC, Sodoyez-Goffaux F, De Vos CJ, Lynn SP, Fields BN -
Persistent infection with a nontransforming RNA virus leads to impaired growth factor receptors and response.
Journal of cellular physiology 1986 Verdin EM, Maratos-Flier E, Carpentier JL, Kahn CR -
Insulin oscillations per se do not affect glucose turnover parameters in normal man.
The Journal of clinical endocrinology and metabolism 1986 Paolisso G, Scheen AJ, Verdin EM, Luyckx AS, Lefebvre PJ -
Adipsic hypernatremia in a patient with pseudotumor cerebri and the primary empty sella syndrome.
Journal of endocrinological investigation 1985 Verdin E, Smitz S, Thibaut A, Born J, Legros JJ, Luyckx A -
Similar metabolic effects of pulsatile versus continuous human insulin delivery during euglycemic, hyperinsulinemic glucose clamp in normal man.
Diabetes 1984 Verdin E, Castillo M, Luyckx AS, Lefebvre PJ -
VIP and the pancreatic cholera syndrome.
The New England journal of medicine 1984 Verdin EM, Green FW -
Circadian profiles of blood glucose and plasma free insulin during treatment with semisynthetic and biosynthetic human insulin, and comparison with conventional monocomponent preparations.
European journal of clinical pharmacology 1983 Castillo M, Nemery A, Verdin E, Lefebvre PJ, Luyckx AS