Eric Nakakura, MD, PhD
Professor
Surgery
School of Medicine

In 2017, he was awarded a $1.2m grant from the Neuroendocrine Tumor Research Foundation (NETRF) to elucidate the causes of small intestinal neuroendocrine tumors (SI-NETs).

Dr. Nakakura earned a medical degree at Stanford Medical School and a doctorate degree in cellular and molecular medicine at the Johns Hopkins University. He completed a residency in general surgery at the Johns Hopkins Medical Institutions and was a specialist registrar in surgery at the John Radcliffe Hospital in Oxford, England. He also completed a fellowship in surgical oncology at the Johns Hopkins Medical Institutions.

Neuroendocrine tumors (NETs) of the small intestine and pancreas frequently spread throughout the body (i.e., metastasize). Surgery is often not possible for patients with advanced disease, and current therapies are ineffective for shrinking tumors and durable palliation of debilitating symptoms, often caused by the release of hormones into the blood. Dr. Nakakura and his colleagues' long-term goal is to find the causes of NETs of the small intestine and pancreas, which can lead to earlier diagnosis and ultimately a cure.

• Expert Consensus Practice Recommendations of the North American Neuroendocrine Tumor Society for the management of high grade gastroenteropancreatic and gynecologic neuroendocrine neoplasms.
  Endocrine-related cancer 2023 Eads JR, Halfdanarson TR, Asmis T, Bellizzi AM, Bergsland EK, Dasari A, El-Haddad G, Frumovitz M, Meyer J, Mittra E, Myrehaug S, Nakakura E, Raj N, Soares HP, Untch B, Vijayvergia N, Chan JA
• Residual Tumor Volume, Not Percent Cytoreduction, Matters for Surgery of Neuroendocrine Liver Metastasis.
  Annals of surgical oncology 2023 Kasai Y, Nakakura EK, Yogo A, Nagai K, Masui T, Hatano E
• Ampullary Adenocarcinoma, Version 1.2023, NCCN Clinical Practice Guidelines in Oncology.
  Journal of the National Comprehensive Cancer Network : JNCCN 2023 Chiorean EG, Chiaro MD, Tempero MA, Malafa MP, Benson AB, Cardin DB, Christensen JA, Chung V, Czito B, Dillhoff M, Donahue TR, Dotan E, Fountzilas C, Glazer ES, Hardacre J, Hawkins WG, Klute K, Ko AH,…
• National Practice Patterns in Malignant Peritoneal Mesothelioma: Updates in Management and Survival.
  Annals of surgical oncology 2023 Calthorpe L, Romero-Hernandez F, Casey M, Nunez M, Conroy PC, Hirose K, Kim A, Kirkwood K, Maker AV, Corvera C, Nakakura E, Alseidi A, Adam MA
• Laparoscopic Gastrectomy for Gastric Cancer.
  JAMA surgery 2023 Hoffman DB, Nakakura EK
• Metastatic colorectal adenocarcinoma tumor purity assessment from whole exome sequencing data.
  PloS one 2023 Tbeileh N, Timmerman L, Mattis AN, Toriguchi K, Kasai Y, Corvera C, Nakakura E, Hirose K, Donner DB, Warren RS, Karelehto E
• Baseline tumor growth rate highlights the heterogeneity of well differentiated gastroenteropancreatic neuroendocrine tumors and predicts for increases in Ki67 index over time.
  Journal of neuroendocrinology 2023 Wang SJ, Whitman J, Paciorek A, Le BK, Nakakura EK, Behr SC, Joseph N, Zhang L, Hope TA, Bergsland EK
• Hypertension Requiring Medication Use: a Silent Predictor of Poor Outcomes After Pancreaticoduodenectomy.
  Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 2023 Lin JJ, Conroy PC, Romero-Hernandez F, Yilma M, Feng J, Hirose K, Nakakura E, Maker AV, Corvera C, Kirkwood K, Alseidi A, Adam MA
• Contemporary Trends in Malignant Peritoneal Mesothelioma: Incidence and Survival in the United States.
  Cancers 2022 Calthorpe L, Romero-Hernandez F, Miller P, Conroy PC, Hirose K, Kim A, Kirkwood K, Nakakura E, Corvera C, Maker AV, Alseidi A, Adam MA
• Hand-Assisted Versus Pure Minimally-Invasive Distal Pancreatectomy: Is There a Downside to Lending a Hand?
  World journal of surgery 2022 Miller PN, Romero-Hernandez F, Conroy P, Calthorpe L, Yilma M, Mohamedaly S, Kelly YM, Feng J, Hirose K, Kirkwood K, Maker AV, Corvera C, Nakakura E, Alseidi A, Adam MA
• Minimally Invasive Distal Pancreatectomy Techniques: A Contemporary Analysis Exploring Trends, Similarities, and Differences to Open Surgery.
  Cancers 2022 Romero-Hernandez F, Mohamedaly S, Miller P, Rodriguez N, Calthorpe L, Conroy PC, Ganjouei AA, Hirose K, Maker AV, Nakakura E, Corvera C, Kirkwood KS, Alseidi A, Adam MA
• Whole genome sequencing reveals the independent clonal origin of multifocal ileal neuroendocrine tumors.
  Genome medicine 2022 Mäkinen N, Zhou M, Zhang Z, Kasai Y, Perez E, Kim GE, Thirlwell C, Nakakura E, Meyerson M
• ASO Visual Abstract: Determining Hospital Volume Threshold for the Safety of Minimally Invasive Pancreaticoduodenectomy: A Contemporary Cutpoint Analysis.
  Annals of surgical oncology 2022 Conroy PC, Calthorpe L, Lin JA, Mohamedaly S, Kim A, Hirose K, Nakakura E, Corvera C, Sosa JA, Sarin A, Kirkwood KS, Alseidi A, Adam MA
• Optimal Staging for Gastric Cancer Starts With High-Resolution Computed Tomography.
  JAMA surgery 2021 Brown AE, Nakakura EK
• Determining Hospital Volume Threshold for Safety of Minimally Invasive Pancreaticoduodenectomy: A Contemporary Cutpoint Analysis.
  Annals of surgical oncology 2021 Conroy PC, Calthorpe L, Lin JA, Mohamedaly S, Kim A, Hirose K, Nakakura E, Corvera C, Sosa JA, Sarin A, Kirkwood KS, Alseidi A, Adam MA
• Preoperative risk stratification of lymph node metastasis for non-functional pancreatic neuroendocrine neoplasm: An international dual-institutional study.
  Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] 2021 Kasai Y, Masui T, Nakakura EK, Nakano K, Sato A, Uchida Y, Yogo A, Nagai K, Anazawa T, Hope TA, Kim GE, Whitman J, Le BK, Takaori K, Bergsland EK, Hatano E, Uemoto S
• Evidence-Based Guidelines for Branch-Duct Intraductal Papillary Mucinous Neoplasm Management: Still a Lot of Room to Grow.
  JAMA surgery 2021 Conroy PC, Nakakura E
• Outcomes after high-dose radiation in the management of neuroendocrine neoplasms.
  PloS one 2021 Chen KS, Lawhn-Heath C, Behr S, Juarez R, Whitman J, Paciorek A, Nakakura EK, Fidelman N, Feng MU, Bergsland EK, Anwar M
• Burden of Ionizing Radiation in the Diagnosis and Management of Necrotizing Pancreatitis.
  Clinical and translational gastroenterology 2021 Thiruvengadam NR, Miranda J, Kim C, Behr S, Corvera C, Dai SC, Kirkwood K, Harris HW, Hirose K, Nakakura E, Ostroff JW, Kochman ML, Arain MA
• Pancreatic Adenocarcinoma, Version 2.2021, NCCN Clinical Practice Guidelines in Oncology.
  Journal of the National Comprehensive Cancer Network : JNCCN 2021 Tempero MA, Malafa MP, Al-Hawary M, Behrman SW, Benson AB, Cardin DB, Chiorean EG, Chung V, Czito B, Del Chiaro M, Dillhoff M, Donahue TR, Dotan E, Ferrone CR, Fountzilas C, Hardacre J, Hawkins WG, …
• Recurrence Patterns After Surgical Resection of Gastroenteropancreatic Neuroendocrine Tumors: Analysis From the National Comprehensive Cancer Network Oncology Outcomes Database.
  Pancreas 2021 Chan H, Zhang L, Choti MA, Kulke M, Yao JC, Nakakura EK, Bloomston M, Benson AB, Shah MH, Strosberg JR, Bergsland EK, Van Loon K
• Minimally Invasive Surgery for Ileal Neuroendocrine Tumors.
  Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 2021 Mahuron KM, Kasai Y, Javeed ZA, Bergsland EK, Hirose K, Corvera CU, Nakakura EK
• Contemporary Management of Hepatic Cyst Disease: Techniques and Outcomes at a Tertiary Hepatobiliary Center.
  Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 2020 Gomez A, Wisneski AD, Luu HY, Hirose K, Roberts JP, Hirose R, Freise CE, Nakakura EK, Corvera CU
• Hybrid Low-Grade Fibromyxoid Sarcoma and Sclerosing Epithelioid Fibrosarcoma of the Pancreas.
  Journal of gastrointestinal cancer 2020 Kramer SP, Bowman CJ, Wang ZJ, Sheahon KM, Nakakura EK, Cho SJ, Umetsu SE, Behr SC
• Randomized Clinical Trial of Nasogastric Tube Placement After Pancreaticoduodenectomy.
  JAMA surgery 2020 Sharib JM, Nakakura EK
• Synchronous Versus Metachronous Colorectal Liver Metastasis Yields Similar Survival in Modern Era.
  The Journal of surgical research 2020 Wisneski AD, Jin C, Huang CY, Warren R, Hirose K, Nakakura EK, Corvera CU
• Awareness of a mesenteric mass as a common manifestation of ileal neuroendocrine tumor.
  Surgical case reports 2020 Kasai Y, Nakakura EK
• Patterns of chromosome 18 loss of heterozygosity in multifocal ileal neuroendocrine tumors.
  Genes, chromosomes & cancer 2020 Zhang Z, Mäkinen N, Kasai Y, Kim GE, Diosdado B, Nakakura E, Meyerson M
• Ampullary stenosis and choledocholithiasis post Roux-En-Y gastric bypass: challenges of biliary access and intervention.
  HPB : the official journal of the International Hepato Pancreato Biliary Association 2020 Wisneski AD, Carter J, Nakakura EK, Posselt A, Rogers SJ, Cello JP, Arain M, Kirkwood KS, Hirose K, Stewart L, Corvera CU
• A novel stratification of mesenteric mass involvement as a predictor of challenging mesenteric lymph node dissection by minimally invasive approach for ileal neuroendocrine tumors.
  Journal of surgical oncology 2020 Kasai Y, Mahuron K, Hirose K, Corvera CU, Kim GE, Hope TA, Shih BE, Warren RS, Bergsland EK, Nakakura EK
• Residual tumor volume discriminates prognosis after surgery for neuroendocrine liver metastasis.
  Journal of surgical oncology 2019 Kasai Y, Hirose K, Corvera CU, Kim GE, Hope TA, Shih BE, Harun N, Kim MO, Warren RS, Bergsland EK, Nakakura EK
• Prognostic impact of a large mesenteric mass >2 cm in ileal neuroendocrine tumors.
  Journal of surgical oncology 2019 Kasai Y, Mahuron K, Hirose K, Corvera CU, Kim GE, Hope TA, Shih BE, Warren RS, Bergsland EK, Nakakura EK
• Adjuvant Therapy for Ampullary Cancer.
  JAMA surgery 2019 Ko AH, Nakakura EK
• High thymidylate synthase gene expression predicts poor outcome after resection of hepatocellular carcinoma.
  PloS one 2019 Donner DB, Nakakura EK, Venook AP, Lenz HJ, Zhang W, Hwang J, Bergsland EK, Lin MH, Toriguchi K, Antonia RJ, Warren RS
• Periprocedural Management of Patients Undergoing Liver Resection or Embolotherapy for Neuroendocrine Tumor Metastases.
  Pancreas 2019 Kwon DH, Paciorek A, Mulvey CK, Chan H, Fidelman N, Meng L, Nakakura EK, Zhang L, Bergsland EK, Van Loon K
• Comparison of Tumor Regression Grading of Residual Pancreatic Ductal Adenocarcinoma Following Neoadjuvant Chemotherapy Without Radiation: Would Fewer Tier-Stratification Be Favorable Toward Standardization?
  The American journal of surgical pathology 2019 Kim SS, Ko AH, Nakakura EK, Wang ZJ, Corvera CU, Harris HW, Kirkwood KS, Hirose R, Tempero MA, Kim GE
• Pancreatic Adenocarcinoma, Version 1.2019.
  Journal of the National Comprehensive Cancer Network : JNCCN 2019 Tempero MA, Malafa MP, Chiorean EG, Czito B, Scaife C, Narang AK, Fountzilas C, Wolpin BM, Al-Hawary M, Asbun H, Behrman SW, Benson AB, Binder E, Cardin DB, Cha C, Chung V, Dillhoff M, Dotan E, …
• Mitogen Inducible Gene-6 Is a Prognostic Marker for Patients with Colorectal Liver Metastases.
  Translational oncology 2019 Donner DB, Ruan DT, Toriguchi K, Bergsland EK, Nakakura EK, Lin MH, Antonia RJ, Warren RS
• A Patient-derived Xenograft Model of Pancreatic Neuroendocrine Tumors Identifies Sapanisertib as a Possible New Treatment for Everolimus-resistant Tumors.
  Molecular cancer therapeutics 2018 Chamberlain CE, German MS, Yang K, Wang J, VanBrocklin H, Regan M, Shokat KM, Ducker GS, Kim GE, Hann B, Donner DB, Warren RS, Venook AP, Bergsland EK, Lee D, Wang Y, Nakakura EK
• Outcomes of arterial bypass preceding resection of retroperitoneal masses involving major vessels.
  The Journal of surgical research 2018 Luu HY, Wang ED, Syed SM, Xu X, Hansen SL, Eichler CM, Nakakura EK
• Progress in the March to Precision Cancer Medicine: Left, Right, Left.
  JAMA surgery 2018 Nakakura EK
• Challenges Staging Neuroendocrine Tumors of the Pancreas, Jejunum and Ileum, and Appendix.
  Annals of surgical oncology 2017 Nakakura EK
• Pancreatic Adenocarcinoma, Version 2.2017, NCCN Clinical Practice Guidelines in Oncology.
  Journal of the National Comprehensive Cancer Network : JNCCN 2017 Tempero MA, Malafa MP, Al-Hawary M, Asbun H, Bain A, Behrman SW, Benson AB, Binder E, Cardin DB, Cha C, Chiorean EG, Chung V, Czito B, Dillhoff M, Dotan E, Ferrone CR, Hardacre J, Hawkins WG, Herman J…
• Gastrocutaneous Fistula in a Patient with Locally Recurrent MSI-High Colorectal Cancer: Local Complications Arising from Therapeutic Response to Immune Checkpoint Blockade.
  Anticancer research 2017 Greene C, Nakakura EK, Ko AH
• The Surgical Management of Small Bowel Neuroendocrine Tumors: Consensus Guidelines of the North American Neuroendocrine Tumor Society.
  Pancreas 2017 Howe JR, Cardona K, Fraker DL, Kebebew E, Untch BR, Wang YZ, Law CH, Liu EH, Kim MK, Menda Y, Morse BG, Bergsland EK, Strosberg JR, Nakakura EK, Pommier RF
• Complicated Case Presentation: Management of Pancreatic Neuroendocrine Tumors in Multiple Endocrine Neoplasia Type 1.
  Pancreas 2017 Mulvey CK, Van Loon K, Bergsland EK, Masharani U, Nakakura EK
• Preoperative FOLFIRINOX for borderline resectable pancreatic cancer: Is radiation necessary in the modern era of chemotherapy?
  Journal of surgical oncology 2016 Kim SS, Nakakura EK, Wang ZJ, Kim GE, Corvera CU, Harris HW, Kirkwood KS, Hirose R, Tempero MA, Ko AH
• Finding the Common Thread in Rare Diseases.
  JAMA surgery 2016 Nakakura EK
• Correcting for respiratory motion in liver PET/MRI: preliminary evaluation of the utility of bellows and navigated hepatobiliary phase imaging.
  EJNMMI physics 2015 Hope TA, Verdin EF, Bergsland EK, Ohliger MA, Corvera CU, Nakakura EK
• Solid pseudopapillary neoplasm of the pancreas head in a pregnant woman: safe pancreaticoduodenectomy postpartum.
  Journal of surgical case reports 2015 Yee AM, Kelly BG, Gonzalez-Velez JM, Nakakura EK
• Simultaneous (68)Ga-DOTA-TOC PET/MRI with gadoxetate disodium in patients with neuroendocrine tumor.
  Abdominal imaging 2015 Hope TA, Pampaloni MH, Nakakura E, VanBrocklin H, Slater J, Jivan S, Aparici CM, Yee J, Bergsland E
• A patient with cholangiocarcinoma demonstrating pathologic complete response to chemotherapy: exploring the role of neoadjuvant therapy in biliary tract cancer.
  Journal of gastrointestinal oncology 2014 Walker EJ, Simko JP, Nakakura EK, Ko AH
• Bone metastases and skeletal-related events from neuroendocrine tumors.
  Endocrine connections 2014 Van Loon K, Zhang L, Keiser J, Carrasco C, Glass K, Ramirez MT, Bobiak S, Nakakura EK, Venook AP, Shah MH, Bergsland EK
• Neuroendocrine tumors of unknown primary: is the primary site really not known?
  JAMA surgery 2014 Bergsland EK, Nakakura EK
• Pancreatic adenocarcinoma, version 2.2014: featured updates to the NCCN guidelines.
  Journal of the National Comprehensive Cancer Network : JNCCN 2014 Tempero MA, Malafa MP, Behrman SW, Benson AB, Casper ES, Chiorean EG, Chung V, Cohen SJ, Czito B, Engebretson A, Feng M, Hawkins WG, Herman J, Hoffman JP, Ko A, Komanduri S, Koong A, Lowy AM, Ma WW, …
• Time to put another surgical dogma to sleep?
  JAMA surgery 2014 Nakakura EK
• Home, sweet home, after surgery.
  JAMA surgery 2014 Nakakura EK
• Incomplete inhibition of phosphorylation of 4E-BP1 as a mechanism of primary resistance to ATP-competitive mTOR inhibitors.
  Oncogene 2013 Ducker GS, Atreya CE, Simko JP, Hom YK, Matli MR, Benes CH, Hann B, Nakakura EK, Bergsland EK, Donner DB, Settleman J, Shokat KM, Warren RS
• Management of well-differentiated gastrointestinal neuroendocrine tumors metastatic to the liver.
  Seminars in oncology 2013 Wang SC, Fidelman N, Nakakura EK
• Reply to P.H. Sugarbaker.
  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2013 Nakakura EK
• Can CT features differentiate between inferior vena cava leiomyosarcomas and primary retroperitoneal masses?
  AJR. American journal of roentgenology 2013 Webb EM, Wang ZJ, Westphalen AC, Nakakura EK, Coakley FV, Yeh BM
• Lymph node sampling rates and predictors of nodal metastasis in pancreatic neuroendocrine tumor resections: the UCSF experience with 149 patients.
  Pancreas 2012 Parekh JR, Wang SC, Bergsland EK, Venook AP, Warren RS, Kim GE, Nakakura EK
• Pancreatic Adenocarcinoma, version 2.2012: featured updates to the NCCN Guidelines.
  Journal of the National Comprehensive Cancer Network : JNCCN 2012 Tempero MA, Arnoletti JP, Behrman SW, Ben-Josef E, Benson AB, Casper ES, Cohen SJ, Czito B, Ellenhorn JD, Hawkins WG, Herman J, Hoffman JP, Ko A, Komanduri S, Koong A, Ma WW, Malafa MP, Merchant NB, …
• Pseudomyxoma peritonei: more questions than answers.
  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2012 Nakakura EK
• Complete and safe resection of challenging retroperitoneal tumors: anticipation of multi-organ and major vascular resection and use of adjunct procedures.
  World journal of surgical oncology 2011 Tseng WW, Wang SC, Eichler CM, Warren RS, Nakakura EK
• Unique patterns of metastases in common and rare types of malignancy.
  Journal of surgical oncology 2011 Leong SP, Nakakura EK, Pollock R, Choti MA, Morton DL, Henner WD, Lal A, Pillai R, Clark OH, Cady B
• Pancreatic adenocarcinoma.
  Journal of the National Comprehensive Cancer Network : JNCCN 2010 Tempero MA, Arnoletti JP, Behrman S, Ben-Josef E, Benson AB, Berlin JD, Cameron JL, Casper ES, Cohen SJ, Duff M, Ellenhorn JD, Hawkins WG, Hoffman JP, Kuvshinoff BW, Malafa MP, Muscarella P, Nakakura …
• Lack of NKX2.2 expression in bronchopulmonary typical carcinoid tumors: implications for patients with neuroendocrine tumor metastases and unknown primary site.
  The Journal of surgical research 2010 Wang YC, Iezza G, Zuraek MB, Jablons DM, Theodore PR, Bergsland EK, Donner DB, Warren RS, Nakakura EK
• Arterial embolization for the management of gastrointestinal hemorrhage from metastatic renal cell carcinoma.
  Journal of vascular and interventional radiology : JVIR 2010 Fidelman N, Freed RC, Nakakura EK, Rosenberg J, Bloom AI
• Identification of unknown primary tumors in patients with neuroendocrine liver metastases.
  Archives of surgery (Chicago, Ill. : 1960) 2010 Wang SC, Parekh JR, Zuraek MB, Venook AP, Bergsland EK, Warren RS, Nakakura EK
• The ETS oncogene family transcription factor FEV identifies serotonin-producing cells in normal and neoplastic small intestine.
  Endocrine-related cancer 2010 Wang YC, Zuraek MB, Kosaka Y, Ota Y, German MS, Deneris ES, Bergsland EK, Donner DB, Warren RS, Nakakura EK
• MicroRNA dynamics in the stages of tumorigenesis correlate with hallmark capabilities of cancer.
  Genes & development 2009 Olson P, Lu J, Zhang H, Shai A, Chun MG, Wang Y, Libutti SK, Nakakura EK, Golub TR, Hanahan D
• Mitogen-inducible gene-6 expression correlates with survival and is an independent predictor of recurrence in BRAF(V600E) positive papillary thyroid cancers.
  Surgery 2008 Ruan DT, Warren RS, Moalem J, Chung KW, Griffin AC, Shen W, Duh QY, Nakakura E, Donner DB, Khanafshar E, Weng J, Clark OH, Kebebew E
• Homeodomain transcription factor NKX2.2 functions in immature cells to control enteroendocrine differentiation and is expressed in gastrointestinal neuroendocrine tumors.
  Endocrine-related cancer 2008 Wang YC, Gallego-Arteche E, Iezza G, Yuan X, Matli MR, Choo SP, Zuraek MB, Gogia R, Lynn FC, German MS, Bergsland EK, Donner DB, Warren RS, Nakakura EK
• Compound muscle action potentials and spontaneous electromyography can be used to identify and protect the femoral nerve during resection of large retroperitoneal tumors.
  Annals of surgical oncology 2008 Guo L, Clark JP, Warren RS, Nakakura EK
• Immunostaining for peroxisome proliferator gamma distinguishes dedifferentiated liposarcoma from other retroperitoneal sarcomas.
  Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2008 Horvai AE, Schaefer JT, Nakakura EK, O'Donnell RJ
• Introduction.
  Surgical oncology 2007 Warren RS, Nakakura EK
• Pancreatic adenocarcinoma. Clinical Practice Guidelines in Oncology.
  Journal of the National Comprehensive Cancer Network : JNCCN 2007 Tempero M, Arnoletti JP, Ben-Josef E, Bhargava P, Casper ES, Kim P, Malafa MP, Nakakura EK, Shibata S, Talamonti M, Wang H, Willett C
• Palliative care for patients with advanced pancreatic and biliary cancers.
  Surgical oncology 2007 Nakakura EK, Warren RS
• Systemic and regional nonsurgical therapy--what is the optimal strategy for metastatic neuroendocrine cancer?
  Surgical oncology clinics of North America 2007 Nakakura EK, Venook AP, Bergsland EK
• Islet cell carcinoma: neuroendocrine tumors of the pancreas and periampullary region.
  Hematology/oncology clinics of North America 2007 Nakakura EK, Bergsland EK
• Cyclin-dependent kinase 5 activity controls cell motility and metastatic potential of prostate cancer cells.
  Cancer research 2006 Strock CJ, Park JI, Nakakura EK, Bova GS, Isaacs JT, Ball DW, Nelkin BD
• Regulation of neuroendocrine differentiation in gastrointestinal carcinoid tumor cells by notch signaling.
  The Journal of clinical endocrinology and metabolism 2005 Nakakura EK, Sriuranpong VR, Kunnimalaiyaan M, Hsiao EC, Schuebel KE, Borges MW, Jin N, Collins BJ, Nelkin BD, Chen H, Ball DW
• Notch signaling induces rapid degradation of achaete-scute homolog 1.
  Molecular and cellular biology 2002 Sriuranpong V, Borges MW, Strock CL, Nakakura EK, Watkins DN, Blaumueller CM, Nelkin BD, Ball DW
• Mammalian Scratch: a neural-specific Snail family transcriptional repressor.
  Proceedings of the National Academy of Sciences of the United States of America 2001 Nakakura EK, Watkins DN, Schuebel KE, Sriuranpong V, Borges MW, Nelkin BD, Ball DW
• Management of hepatocellular carcinoma.
  Oncology (Williston Park, N.Y.) 2000 Nakakura EK, Choti MA
• Long-term survival of solid organ allografts by brief anti-lymphocyte function-associated antigen-1 monoclonal antibody monotherapy.
  Transplantation 1996 Nakakura EK, Shorthouse RA, Zheng B, McCabe SM, Jardieu PM, Morris RE
• A non-lymphocyte-depleting monoclonal antibody to the adhesion molecule LFA-1 (CD11a) prevents sensitization to alloantigens and effectively prolongs the survival of heart allografts.
  Transplantation proceedings 1993 Nakakura EK, McCabe SM, Zheng B, Shorthouse RA, Scheiner TM, Blank G, Jardieu PM, Morris RE
• Potent and effective prolongation by anti-LFA-1 monoclonal antibody monotherapy of non-primarily vascularized heart allograft survival in mice without T cell depletion.
  Transplantation 1993 Nakakura EK, McCabe SM, Zheng B, Shorthouse RA, Scheiner TM, Blank G, Jardieu PM, Morris RE