Eric Lam, PhD
Assistant Adjunct Professor
Biochemistry and Biophysics
School of Medicine

Publications (28)

Top publication keywords:
Smad3 ProteinSTAT5 Transcription FactorCancer PainHong KongAurora Kinase ACarcinoma, HepatocellularTissue Inhibitor of Metalloproteinase-1Cancer-Associated FibroblastsLiver NeoplasmsPapillomavirus VaccinesPapillomavirus InfectionsCCAAT-Enhancer-Binding ProteinsTumor MicroenvironmentCarcinogenesisSp1 Transcription Factor

• Correction: H19/let-7/LIN28 reciprocal negative regulatory circuit promotes breast cancer stem cell maintenance.
  Cell death & disease 2024 Peng F, Li TT, Wang KL, Xiao GQ, Wang JH, Zhao HD, Kang ZJ, Fan WJ, Zhu LL, Li M, Cui B, Zheng FM, Wang HJ, Lam EW, Wang B, Xu J, Liu Q
• Evaluation of ST6Gal1 expression and clinicopathological significance in human glioma.
  Clinical neuropathology 2024 Zhou Y, Wu Y, Shen D, Wang Q, Thomas AM, Li S, Shi F, Lam EW, Qin H
• Individual Participant Data Meta-Analyses for Diagnostic Accuracy Research: Challenges and Lessons Learned from the LI-RADS IPD Group.
  Radiology. Imaging cancer 2024 Costa AF, McInnes MDF, van der Pol CB, Lam E, Dawit H, Salameh JP, Levis B, Bashir MR
• Comprehensive pan-cancer analysis identifies the RNA-binding protein LRPPRC as a novel prognostic and immune biomarker.
  Life sciences 2024 Wu Z, Liu X, Xie F, Ma C, Lam EW, Kang N, Jin D, Yan J, Jin B
• Editorial: New insights into fibrotic signaling in cancer.
  Frontiers in oncology 2024 Tang PM, Lam EW, Mussal F, Zhang D, Li C

Show all (23 more) Hide

• LI-RADS CT and MRI Ancillary Feature Association with Hepatocellular Carcinoma and Malignancy: An Individual Participant Data Meta-Analysis.
  Radiology 2024 Dawit H, Lam E, McInnes MDF, van der Pol CB, Bashir MR, Salameh JP, Levis B, Sirlin CB, Chernyak V, Choi SH, Kim SY, Fraum TJ, Tang A, Jiang H, Song B, Wang J, Wilson SR, Kwon H, Kierans AS, Joo I, …
• Individual Participant Data Meta-Analysis of LR-5 in LI-RADS Version 2018 versus Revised LI-RADS for Hepatocellular Carcinoma Diagnosis.
  Radiology 2023 Goins SM, Jiang H, van der Pol CB, Salameh JP, Lam E, Adamo RG, McInnes MDF, Costa AF, Tang A, Alhasan AS, Allen BC, Reiner CS, Clarke C, Cerny M, Wang J, Choi SH, Fraum TJ, Ludwig DR, Song B, Joo I, …
• Pyrroline-5-carboxylate reductase 1 reprograms proline metabolism to drive breast cancer stemness under psychological stress.
  Cell death & disease 2023 Cui B, He B, Huang Y, Wang C, Luo H, Lu J, Su K, Zhang X, Luo Y, Zhao Z, Yang Y, Zhang Y, An F, Wang H, Lam EW, Kelley KW, Wang L, Liu Q, Peng F
• Cancer cell employs a microenvironmental neural signal trans-activating nucleus-mitochondria coordination to acquire stemness.
  Signal transduction and targeted therapy 2023 He B, Gao R, Lv S, Chen A, Huang J, Wang L, Feng Y, Feng J, Liu B, Lei J, Deng B, He B, Cui B, Peng F, Yan M, Wang Z, Lam EW, Jin B, Shao Z, Li Y, Jiao J, Wang X, Liu Q
• Awareness, perceptions, and acceptance of human papillomavirus vaccination among parents in Hong Kong.
  Hong Kong medical journal = Xianggang yi xue za zhi 2023 Lam EWH, Ngan HYS, Kun KY, Li DFH, Wan WY, Chan PKS
• Conversion Strategy for LI-RADS Category 5 Observations across Versions 2014, 2017, and 2018.
  Radiology 2023 Goins SM, Adamo RG, Lam E, Costa AF, van der Pol CB, Salameh JP, Dawit H, McInnes MDF, Bashir MR
• High expression of cytoplasmic FOXO3 protein associated with poor prognosis of rectal cancer patients: A study from Swedish clinical trial of preoperative radiotherapy to big database analysis.
  Heliyon 2023 Cui W, Xie N, Lam EW, Hahn-Stromberg V, Liu N, Zhang H, Sun XF
• Smad3 is essential for polarization of tumor-associated neutrophils in non-small cell lung carcinoma.
  Nature communications 2023 Chung JY, Tang PC, Chan MK, Xue VW, Huang XR, Ng CS, Zhang D, Leung KT, Wong CK, Lee TL, Lam EW, Nikolic-Paterson DJ, To KF, Lan HY, Tang PM
• A multi-firearm, multi-orientation audio dataset of gunshots.
  Data in brief 2023 Kabealo R, Wyatt S, Aravamudan A, Zhang X, Acaron DN, Dao MP, Elliott D, Smith AO, Otero CE, Otero LD, Anagnostopoulos GC, Peter AM, Jones W, Lam E
• Single-cell RNA sequencing uncovers a neuron-like macrophage subset associated with cancer pain.
  Science advances 2022 Tang PC, Chung JY, Liao J, Chan MK, Chan AS, Cheng G, Li C, Huang XR, Ng CS, Lam EW, Zhang D, Ho YP, To KF, Leung KT, Jiang X, Ko H, Lee TL, Lan HY, Tang PM
• Targeting epiregulin in the treatment-damaged tumor microenvironment restrains therapeutic resistance.
  Oncogene 2022 Wang C, Long Q, Fu Q, Xu Q, Fu D, Li Y, Gao L, Guo J, Zhang X, Lam EW, Campisi J, Sun Y
• Chronic Inflammation Pathway NF-κB Cooperates with Epigenetic Reprogramming to Drive the Malignant Progression of Glioblastoma.
  International journal of biological sciences 2022 Lin K, Gao W, Chen N, Yang S, Wang H, Wang R, Xie F, Meng J, Lam EW, Li S, Cheng W, Chen P, Wu H, Yan J, Jin D, Jin B
• Sp1 induced gene TIMP1 is related to immune cell infiltration in glioblastoma.
  Scientific reports 2022 Liu L, Yang S, Lin K, Yu X, Meng J, Ma C, Wu Z, Hao Y, Chen N, Ge Q, Gao W, Wang X, Lam EW, Zhang L, Li F, Jin B, Jin D
• Correction: A Novel Small Molecule Aurora Kinase Inhibitor Attenuates Breast Tumor Initiating Cells and Overcomes Drug Resistance.
  Molecular cancer therapeutics 2022 Zheng FM, Long ZJ, Hou ZJ, Luo Y, Xu LZ, Xia JL, Lai XJ, Liu JW, Wang X, Kamran M, Yan M, Shao SJ, Lam EW, Wang SW, Lu G, Liu Q
• MCF-7 Drug Resistant Cell Lines Switch Their Lipid Metabolism to Triple Negative Breast Cancer Signature.
  Cancers 2021 Adriá-Cebrián J, Guaita-Esteruelas S, Lam EW, Rodríguez-Balada M, Capellades J, Girona J, Jimenez-Santamaria AM, Yanes O, Masana L, Gumà J
• Smad3 Promotes Cancer-Associated Fibroblasts Generation via Macrophage-Myofibroblast Transition.
  Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2021 Tang PC, Chung JY, Xue VW, Xiao J, Meng XM, Huang XR, Zhou S, Chan AS, Tsang AC, Cheng AS, Lee TL, Leung KT, Lam EW, To KF, Tang PM, Lan HY
• Modulation of oxidative phosphorylation augments antineoplastic activity of mitotic aurora kinase inhibition.
  Cell death & disease 2021 Zhang Z, Zeng D, Zhang W, Chen A, Lei J, Liu F, Deng B, Zhuo J, He B, Yan M, Lei X, Wang S, Lam EW, Liu Q, Wang Z
• Cancer cell immune mimicry delineates onco-immunologic modulation.
  iScience 2021 Gao R, He B, Huang Q, Wang Z, Yan M, Lam EW, Lin S, Wang B, Liu Q
• Targeting cancer cell plasticity by HDAC inhibition to reverse EBV-induced dedifferentiation in nasopharyngeal carcinoma.
  Signal transduction and targeted therapy 2021 Xie J, Wang Z, Fan W, Liu Y, Liu F, Wan X, Liu M, Wang X, Zeng D, Wang Y, He B, Yan M, Zhang Z, Zhang M, Hou Z, Wang C, Kang Z, Fang W, Zhang L, Lam EW, Guo X, Yan J, Zeng Y, Chen M, Liu Q
• Altered Serum Metabolic Profile Assessed by Advanced 1H-NMR in Breast Cancer Patients.
  Cancers 2021 Gumà J, Adriá-Cebrián J, Ruiz-Aguado B, Albacar C, Girona J, Rodríguez-Calvo R, Martínez-Micaelo N, Lam EWF, Masana L, Guaita-Esteruelas S
• USMB-shMincle: a virus-free gene therapy for blocking M1/M2 polarization of tumor-associated macrophages.
  Molecular therapy oncolytics 2021 Xue VW, Chung JY, Tang PC, Chan AS, To TH, Chung JS, Mussal F, Lam EW, Li C, To KF, Leung KT, Lan HY, Tang PM
• Immune-Related Endocrine Dysfunctions in Combined Modalities of Treatment: Real-World Data.
  Cancers 2021 Chan WL, Choi HC, Ho PP, Lau JK, Tse RP, Au J, Lam V, Liu R, Ho I, Wong C, Cheung B, Lam E, Chow D, Lam KO, Yuen KK, Kwong DL
• KDM4 Orchestrates Epigenomic Remodeling of Senescent Cells and Potentiates the Senescence-Associated Secretory Phenotype.
  Nature aging 2021 Zhang B, Long Q, Wu S, Xu Q, Song S, Han L, Qian M, Ren X, Liu H, Jiang J, Guo J, Zhang X, Chang X, Fu Q, Lam EW, Campisi J, Kirkland JL, Sun Y