Elze Rackaityte, PhD
Assistant Professor
Ob/Gyn, Reproductive Sciences
School of Medicine
Grants and Projects
Show all (2) Hide
Publications (25)
Top publication keywords:
AutoimmunityClonal DeletionMicrobiotaIntestinesImmune ToleranceGastrointestinal MicrobiomeBacteriaT-LymphocytesAdaptive ImmunityFetusMicrobial ViabilityClonal AnergyBacteriophagesGastrointestinal TractAutoantibodies
-
Evidence for maternal autoantibodies in the pathogenesis of preterm birth.
Nature immunology 2026 Rackaityte E, Borges B, Kortbawi HM, Miller HS, Shao SJ, Zorn KC, Caspar C, Wong R, McCarthy F, Creery JS, Mayer M, Raghavan M, Kouame E, Puccinelli RR, Kistler AL, Yu DJL, Ganem SR, DeRisi A, Kawaja … -
Evidence for Maternal Autoantibodies in the Pathogenesis of Preterm Birth.
medRxiv : the preprint server for health sciences 2025 Rackaityte E, Borges B, Kortbawi HM, Miller HS, Shao SJ, Zorn KC, Caspar C, Wong R, McCarthy F, Creery JS, Mayer M, Kouame E, Puccinelli RR, Kistler AL, Yu DJL, Ganem SR, DeRisi A, Kawaja Q, Wang CY, … -
Nr4a1 and Nr4a3 redundantly control clonal deletion and contribute to an anergy-like transcriptome in auto-reactive thymocytes to impose tolerance in mice.
Nature communications 2025 Nielsen HV, Yang L, Mueller JL, Ritter AJ, Hiwa R, Proekt I, Rackaityte E, Aylard D, Gupta M, Scharer CD, Anderson MS, Au-Yeung BB, Zikherman J -
Molecular mimicry in multisystem inflammatory syndrome in children.
Nature 2024 Bodansky A, Mettelman RC, Sabatino JJ, Vazquez SE, Chou J, Novak T, Moffitt KL, Miller HS, Kung AF, Rackaityte E, Zamecnik CR, Rajan JV, Kortbawi H, Mandel-Brehm C, Mitchell A, Wang CY, Saxena A, Zorn… -
12,13-diHOME Promotes Inflammatory Macrophages and Epigenetically Modifies Their Capacity to Respond to Microbes and Allergens.
Journal of immunology research 2024 Lin DL, Magnaye KM, Porsche CE, Levan SR, Rackaityte E, Özçam M, Lynch SV
Show all (20 more) Hide
-
Unveiling the proteome-wide autoreactome enables enhanced evaluation of emerging CAR T cell therapies in autoimmunity.
The Journal of clinical investigation 2024 Bodansky A, Yu DJ, Rallistan A, Kalaycioglu M, Boonyaratanakornkit J, Green DJ, Gauthier J, Turtle CJ, Zorn K, O'Donovan B, Mandel-Brehm C, Asaki J, Kortbawi H, Kung AF, Rackaityte E, Wang CY, Saxena … -
Unveiling the autoreactome: Proteome-wide immunological fingerprints reveal the promise of plasma cell depleting therapy.
medRxiv : the preprint server for health sciences 2023 Bodansky A, Yu DJ, Rallistan A, Kalaycioglu M, Boonyaratanakornkit J, Green DJ, Gauthier J, Turtle CJ, Zorn K, O'Donovan B, Mandel-Brehm C, Asaki J, Kortbawi H, Kung AF, Rackaityte E, Wang CY, Saxena … -
Validation of a murine proteome-wide phage display library for identification of autoantibody specificities.
JCI insight 2023 Rackaityte E, Proekt I, Miller HS, Ramesh A, Brooks JF, Kung AF, Mandel-Brehm C, Yu D, Zamecnik CR, Bair R, Vazquez SE, Sunshine S, Abram CL, Lowell CA, Rizzuto G, Wilson MR, Zikherman J, Anderson MS,… -
Autoantibodies against type I IFNs in humans with alternative NF-κB pathway deficiency.
Nature 2023 Le Voyer T, Parent AV, Liu X, Cederholm A, Gervais A, Rosain J, Nguyen T, Perez Lorenzo M, Rackaityte E, Rinchai D, Zhang P, Bizien L, Hancioglu G, Ghillani-Dalbin P, Charuel JL, Philippot Q, Gueye MS… -
Validation of a murine proteome-wide phage display library for the identification of autoantibody specificities.
bioRxiv : the preprint server for biology 2023 Rackaityte E, Proekt I, Miller HS, Ramesh A, Brooks JF, Kung AF, Mandel-Brehm C, Yu D, Zamecnik C, Bair R, Vazquez SE, Sunshine S, Abram CL, Lowell CA, Rizzuto G, Wilson MR, Zikherman J, Anderson MS, … -
Heritable vaginal bacteria influence immune tolerance and relate to early-life markers of allergic sensitization in infancy.
Cell reports. Medicine 2022 McCauley KE, Rackaityte E, LaMere B, Fadrosh DW, Fujimura KE, Panzer AR, Lin DL, Lynch KV, Halkias J, Mendoza VF, Burt TD, Bendixsen C, Barnes K, Kim H, Jones K, Ownby DR, Johnson CC, Seroogy CM, Gern… -
Genome-Wide Knockout Screen Identifies Human Sialomucin CD164 as an Essential Entry Factor for Lymphocytic Choriomeningitis Virus.
mBio 2022 Liu J, Knopp KA, Rackaityte E, Wang CY, Laurie MT, Sunshine S, Puschnik AS, DeRisi JL -
Impaired immune signaling and changes in the lung microbiome precede secondary bacterial pneumonia in COVID-19.
medRxiv : the preprint server for health sciences 2021 Tsitsiklis A, Zha BS, Byrne A, DeVoe C, Rackaityte E, Levan S, Sunshine S, Mick E, Ghale R, Love C, Tarashansky AJ, Pisco A, Albright J, Jauregui A, Sarma A, Neff N, Serpa PH, Deiss TJ, Kistler A, … -
Impaired immune signaling and changes in the lung microbiome precede secondary bacterial pneumonia in COVID-19.
Research square 2021 Tsitsiklis A, Zha BS, Byrne A, Devoe C, Levan S, Rackaityte E, Sunshine S, Mick E, Ghale R, Jauregui A, Sarma A, Neff N, Serpa PH, Deiss TJ, Kistler A, Carrillo S, Ansel KM, Leligdowicz A, Christenson… -
Corroborating evidence refutes batch effect as explanation for fetal bacteria.
Microbiome 2021 Rackaityte E, Halkias J, Fukui EM, Mendoza VF, Hayzelden C, Crawford ED, Fujimura KE, Burt TD, Lynch SV -
Rapid deployment of SARS-CoV-2 testing: The CLIAHUB.
PLoS pathogens 2020 Crawford ED, Acosta I, Ahyong V, Anderson EC, Arevalo S, Asarnow D, Axelrod S, Ayscue P, Azimi CS, Azumaya CM, Bachl S, Bachmutsky I, Bhaduri A, Brown JB, Batson J, Behnert A, Boileau RM, Bollam SR, … -
The human microbiome in the 21st century.
Nature communications 2020 Rackaityte E, Lynch SV -
Mechanisms of Fetal T Cell Tolerance and Immune Regulation.
Frontiers in immunology 2020 Rackaityte E, Halkias J -
Viable bacterial colonization is highly limited in the human intestine in utero.
Nature medicine 2020 Rackaityte E, Halkias J, Fukui EM, Mendoza VF, Hayzelden C, Crawford ED, Fujimura KE, Burt TD, Lynch SV -
CD161 contributes to prenatal immune suppression of IFNγ-producing PLZF+ T cells.
The Journal of clinical investigation 2019 Halkias J, Rackaityte E, Hillman SL, Aran D, Mendoza VF, Marshall LR, MacKenzie TC, Burt TD -
Rules of engagement in the gut microbiome.
Nature medicine 2018 Rackaityte E, Lynch SV -
YeeJ is an inverse autotransporter from Escherichia coli that binds to peptidoglycan and promotes biofilm formation.
Scientific reports 2017 Martinez-Gil M, Goh KGK, Rackaityte E, Sakamoto C, Audrain B, Moriel DG, Totsika M, Ghigo JM, Schembri MA, Beloin C -
Neonatal gut microbiota associates with childhood multisensitized atopy and T cell differentiation.
Nature medicine 2016 Fujimura KE, Sitarik AR, Havstad S, Lin DL, Levan S, Fadrosh D, Panzer AR, LaMere B, Rackaityte E, Lukacs NW, Wegienka G, Boushey HA, Ownby DR, Zoratti EM, Levin AM, Johnson CC, Lynch SV -
Novel strategies for enhanced removal of persistent Bacillus anthracis surrogates and Clostridium difficile spores from skin.
PloS one 2013 Nerandzic MM, Rackaityte E, Jury LA, Eckart K, Donskey CJ -
Porphyromonas gingivalis: keeping the pathos out of the biont.
Journal of oral microbiology 2013 Cugini C, Klepac-Ceraj V, Rackaityte E, Riggs JE, Davey ME