Elliott Vichinsky, MD
Professor
Pediatrics
School of Medicine

Protecting and advancing the health and well-being of children through clinical care, teaching, and research; hematology; hemoglobin, hemoglobin disorders; designing and leading clinical research studies; understanding the pathophysiology of hemoglobinopathies; comprehensive clinical care; evaluating therapeutic interventions to improve disease outcomes; expanding patient access to quality healthcare; improving patient quality of life; health equity; establishing, improving, and expanding networks of care for hemoglobinopathy patients; designing and leading collaborative multi-center trials; forming and leading regional, national, and international collaborative research networks; implementation studies; data collection; registry and surveillance systems for hemoglobinopathies; expanding enrollment in clinical trials; accelerating the pace of clinical research; writing, editing, and reviewing grant applications, abstracts, peer-reviewed manuscripts, chapters, and books; publishing research findings; presenting research findings to diverse audiences; developing, updating, publishing, and teaching standards of care guidelines for optimal management of hemoglobinopathy patients; training and expanding the healthcare workforce knowledgeable in the standard of care treatments; developing and teaching academic curricula; junior and mid-career faculty career development; recruiting and mentoring under-represented faculty in medicine and science; diversity in medicine and research; mentoring others to become leading independent clinician scientists equipped to advance the field; sickle cell disease; sickle cell anemia; sickle cell trait; pain management; acute chest syndrome; avascular necrosis; bone disease; organ failure; priapism; pulmonary hypertension; hemolysis; alloimmunization; iron dysregulation; brain iron; chelation therapy, neurodegeneration; NBIA; PKAN; thalassemia syndromes; alpha thalassemia major; fetal hemoglobin; in utero transfusion, intrauterine stem cell transplantation; Bart's fetalis syndrome; stroke; transcranial doppler; TCD screening; prenatal and newborn screening; genetic counseling; BMT; gene and stem cell therapy; red blood cell biology; laboratory medicine; pheresis medicine; transfusion medicine; global medicine; political advocacy to improve healthcare policy; collaborating with community advisory boards and involving them as part of the research team to ensure our research activities are guided by the needs and concerns of people affected.

I am an endowed physician and professor in residence at the University of California San Francisco Benioff Children's Hospital in Oakland, California. For nearly 40 years I have been on forefront of research into better treatments and potential cures for hemoglobinopathies. My directorship of the largest and most comprehensive program for individuals with sickle cell disease and their families in the western United States began in 1978. Renamed the UCSF Sickle Cell Center of Excellence and rebuilt stronger, my center continues its mission to improve clinical outcomes and quality of life for individuals living with sickle cell and their families across the lifespan.

I direct the Hemoglobinopathy Reference Laboratory for the State of California at UCSF Benioff Children's Hospital Oakland, which has been a national resource to aid in the diagnosis of clinically relevant hemoglobinopathies since 1973 (the laboratory has been a vital component of the state's newborn screening follow-up program, evaluating clinically relevant hemoglobin variants, providing confirmatory testing on all newborns in California with presumptive sickle cell disease, beta thalassemia or HbH disease, and assisting NBS programs across the country.

Throughout my career I have developed successful teams that bring basic and clinical investigators together in partnership with the biomedical and pharmaceutical industry to develop and evaluate new treatments for hemoglobinopathies. I was lead investigator of the safety and efficacy of several important therapies for sickle cell disease, such as arginine, mitapivat, and other promising drug trials. I was the senior/principal author of the drug trials of voxelotor and glutamine and played a pivotal role securing their FDA-approval.

In addition to leading the development of novel therapeutics, I serve as PI or Co-PI on several key evidence-based clinical research networks, such as the American Society of Hematology’s Research Collaborative (as the Western States Sickle Cell Disease Clinical Trials Network); the NHLBI’s SC-Links study (Linking the Sickle Cell Community, Providers and Systems to Improve Sickle Cell Disease Care (SCDIC); the NHLBI’s REDS-IV-P study (Recipient Epidemiology and Donor Evaluation Study-IV-Pediatric, Domestic Hubs); the Network for California Sickle Cell Care and HRSA’s Pacific Sickle Cell Regional Collaboration, which aims to reduce morbidity and mortality by improving the quality of coordinated and comprehensive services to individuals with sickle cell disease and their families. These networks link together researchers, clinicians, and communities affected by sickle cell disease to guide evidence-based treatment and improve patient care.

I am commitment to fostering the next generation of translational and clinical scientists and guide the academic development of my colleagues through participation in programs like the American Society of Pediatric Hematology Oncology’s Mid-Career Mentoring Program, the Doris Duke Charitable Foundation’s Clinical Research Mentorship Program, and the NIH’s Mentored Research Scientist Career Development Program (K series). I have supported young students from disadvantaged backgrounds explore potential career opportunities in healthcare and science through my involvement in the UCSF Summer Student Program.

I am a passionate advocate to improve healthcare policies for people living with sickle cell disease. Over the years I have provided scientific insight and medical expertise to legislators and health care policy makers at the regional, state, and federal levels of government, including my work with California Congresswoman Barbara Lee, State Superintendent of Public Instruction Tony Thurmond, California Assemblymember Mike Gibson, the California State Health Subcommittee, and multiple mayoral leaders of the City of Oakland, California to improve and increase access to comprehensive care for Californians living with sickle cell disease.

• Improving healthspan among people with sickle cell disease: Leveraging precision health in an era of treatments with curative intent.
  American journal of hematology 2024 Yu EA, Zacharias HU, Kelly S, Vichinsky E
• Sickle Cell Disease Treatment with Arginine Therapy (STArT): study protocol for a phase 3 randomized controlled trial.
  Trials 2023 Rees CA, Brousseau DC, Cohen DM, Villella A, Dampier C, Brown K, Campbell A, Chumpitazi CE, Airewele G, Chang T, Denton C, Ellison A, Thompson A, Ahmad F, Bakshi N, Coleman KD, Leibovich S, Leake D, …
• Fertility and Pregnancy in Women with Transfusion-Dependent Thalassemia.
  Hematology/oncology clinics of North America 2023 Sayani FA, Singer ST, Carlberg KT, Vichinsky EP
• The Clinical Phenotypes of Alpha Thalassemia.
  Hematology/oncology clinics of North America 2023 Lal A, Vichinsky E
• Assessment of total and unbound cell-free heme in plasma of patients with sickle cell disease.
  Experimental biology and medicine (Maywood, N.J.) 2023 Vissa M, Larkin SK, Vichinsky EP, Kuypers FA, Soupene E
• COVID-19 Infection and Outcomes in Newborn Screening Cohorts of Sickle Cell Trait and Sickle Cell Disease in Michigan and Georgia.
  Journal of pediatric hematology/oncology 2023 Paulukonis ST, Snyder A, Smeltzer MP, Sutaria AN, Hurden I, Latta K, Chennuri S, Vichinsky E, Reeves SL
• The impact of in utero transfusions on perinatal outcomes in patients with alpha thalassemia major: the UCSF registry.
  Blood advances 2023 Schwab ME, Lianoglou BR, Gano D, Gonzalez Velez J, Allen IE, Arvon R, Baschat A, Bianchi DW, Bitanga M, Bourguignon A, Brown RN, Chen B, Chien M, Davis-Nelson S, de Laat MWM, Ekwattanakit S, Gollin Y,…
• Development of a Thalassemia International Prognostic Scoring System (TIPSS).
  Blood cells, molecules & diseases 2022 Vitrano A, Musallam KM, Meloni A, Karimi M, Daar S, Ricchi P, Costantini S, Vlachaki E, Di Marco V, El-Beshlawy A, Hajipour M, Ansari SH, Filosa A, Ceci A, Singer ST, Naserullah ZA, Pepe A, …
• Safety and efficacy of mitapivat, an oral pyruvate kinase activator, in adults with non-transfusion dependent α-thalassaemia or β-thalassaemia: an open-label, multicentre, phase 2 study.
  Lancet (London, England) 2022 Kuo KHM, Layton DM, Lal A, Al-Samkari H, Bhatia J, Kosinski PA, Tong B, Lynch M, Uhlig K, Vichinsky EP
• The effects of glutamine supplementation on markers of apoptosis and autophagy in sickle cell disease peripheral blood mononuclear cells.
  Complementary therapies in medicine 2022 Walter PB, Hohman LS, Rokeby A, Lum JJ, Hagar R, Lavrisha L, Saulys A, Kuypers FA, Vichinsky E, Morris CR
• Transitioning Adolescents With Sickle Cell Disease From Pediatric to Adult Care: Results From a New Survey of Health Care Professionals.
  Journal of pediatric hematology/oncology 2022 Shah NR, Treadwell MJ, Vichinsky E
• Implications for the metabolic fate of oral glutamine supplementation within plasma and erythrocytes of patients with sickle cell disease: A pharmacokinetics study.
  Complementary therapies in medicine 2022 Morris CR, Kuypers FA, Hagar R, Larkin S, Lavrisha L, Saulys A, Vichinsky EP, Suh JH
• Consensus statement for the perinatal management of patients with α thalassemia major.
  Blood advances 2021 MacKenzie TC, Amid A, Angastiniotis M, Butler C, Gilbert S, Gonzalez J, Keller RL, Kharbanda S, Kirby-Allen M, Koenig BA, Kyono W, Lal A, Lianoglou BR, Norton ME, Ogasawara KK, Panchalee T, Rosner M, …
• Risk of mortality from anemia and iron overload in nontransfusion-dependent β-thalassemia.
  American journal of hematology 2021 Musallam KM, Vitrano A, Meloni A, Pollina SA, Karimi M, El-Beshlawy A, Hajipour M, Di Marco V, Ansari SH, Filosa A, Ricchi P, Ceci A, Daar S, Vlachaki E, Singer ST, Naserullah ZA, Pepe A, Scondotto S,…
• An update on the US adult thalassaemia population: a report from the CDC thalassaemia treatment centres.
  British journal of haematology 2021 Chapin J, Cohen AR, Neufeld EJ, Vichinsky E, Giardina PJ, Boudreaux J, Le BC, Kenney K, Trimble S, Thompson AA
• Anterior Pituitary Volume in Patients with Transfusion Dependent Anemias: Volumetric Approaches and Relation to Pituitary MRI‑R2.
  Clinical neuroradiology 2021 Berliner C, Wang ZJ, Singer ST, Grosse R, McDonough RV, Padua E, Yuan Q, Weyhmiller M, James E, Vichinsky E, Adam G, Yamamura J, Bannas P, Fischer R, Schoennagel BP
• Primary HBB gene mutation severity and long-term outcomes in a global cohort of β-thalassaemia.
  British journal of haematology 2021 Musallam KM, Vitrano A, Meloni A, Addario Pollina S, Di Marco V, Hussain Ansari S, Filosa A, Ricchi P, Ceci A, Daar S, Vlachaki E, Singer ST, Naserullah ZA, Pepe A, Scondotto S, Dardanoni G, Karimi M,…
• Survival and causes of death in 2,033 patients with non-transfusion-dependent β-thalassemia
  Haematologica 2021 Musallam KM, Vitrano A, Meloni A, Pollina SA, Karimi M, El-Beshlawy A, Hajipour M, Di Marco V, Ansari SH, Filosa A, Ricchi P, Ceci A, Daar S, Vlachaki E, Singer ST, Naserullah ZA, Pepe A, Scondotto S,…
• The transfusion management of beta thalassemia in the United States.
  Transfusion 2021 Lal A, Wong T, Keel S, Pagano M, Chung J, Kamdar A, Rao L, Ikeda A, Puthenveetil G, Shah S, Yu J, Vichinsky E
• Time to rethink haemoglobin threshold guidelines in sickle cell disease.
  British journal of haematology 2021 Ballas SK, Kuypers FA, Gordeuk VR, Hankins JS, Thompson AA, Vichinsky E
• Pituitary iron and factors predictive of fertility status in transfusion dependent thalassemia.
  Haematologica 2021 Singer ST, Fischer R, Allen I, Lal A, Vichinsky E, Yuan Q, Wang ZJ
• Stable to improved cardiac and pulmonary function in children with high-risk sickle cell disease following haploidentical stem cell transplantation.
  Bone marrow transplantation 2021 Friedman D, Dozor AJ, Milner J, D'Souza M, Talano JA, Moore TB, Shenoy S, Shi Q, Walters MC, Vichinsky E, Parsons SK, Braniecki S, Moorthy CR, Ayello J, Flower A, Morris E, Mahanti H, Fabricatore S, …
• Voxelotor in adolescents and adults with sickle cell disease (HOPE): long-term follow-up results of an international, randomised, double-blind, placebo-controlled, phase 3 trial.
  The Lancet. Haematology 2021 Howard J, Ataga KI, Brown RC, Achebe M, Nduba V, El-Beshlawy A, Hassab H, Agodoa I, Tonda M, Gray S, Lehrer-Graiwer J, Vichinsky E
• Voxelotor for the treatment of sickle cell disease.
  Expert review of hematology 2021 Vissa M, Vichinsky E
• Iron Deficiency: Implications Before Anemia.
  Pediatrics in review 2021 Tong S, Vichinsky E
• A complication risk score to evaluate clinical severity of thalassaemia syndromes.
  British journal of haematology 2020 Vitrano A, Meloni A, Addario Pollina W, Karimi M, El-Beshlawy A, Hajipour M, Di Marco V, Hussain Ansari S, Filosa A, Ricchi P, Ceci A, Daar S, Titi Singer S, Naserullah ZA, Pepe A, Scondotto S, …
• Effect of Inhaled Cannabis for Pain in Adults With Sickle Cell Disease: A Randomized Clinical Trial.
  JAMA network open 2020 Abrams DI, Couey P, Dixit N, Sagi V, Hagar W, Vichinsky E, Kelly ME, Connett JE, Gupta K
• American Society of Hematology 2020 guidelines for sickle cell disease: prevention, diagnosis, and treatment of cerebrovascular disease in children and adults.
  Blood advances 2020 DeBaun MR, Jordan LC, King AA, Schatz J, Vichinsky E, Fox CK, McKinstry RC, Telfer P, Kraut MA, Daraz L, Kirkham FJ, Murad MH
• Influence of sickle cell disease on susceptibility to HIV infection.
  PloS one 2020 Kelly S, Jacobs ES, Stone M, Keating SM, Lee TH, Chafets D, Heitman J, Dimapasoc M, Operskalski E, Hagar W, Vichinsky E, Busch MP, Norris PJ, Custer B, Recipient Epidemiology and Donor Evaluation …
• Identifying Clinical and Research Priorities in Sickle Cell Lung Disease. An Official American Thoracic Society Workshop Report.
  Annals of the American Thoracic Society 2019 Ruhl AP, Sadreameli SC, Allen JL, Bennett DP, Campbell AD, Coates TD, Diallo DA, Field JJ, Fiorino EK, Gladwin MT, Glassberg JA, Gordeuk VR, Graham LM, Greenough A, Howard J, Kato GJ, Knight-Madden J,…
• Safety and efficacy of deferiprone for pantothenate kinase-associated neurodegeneration: a randomised, double-blind, controlled trial and an open-label extension study.
  The Lancet. Neurology 2019 Klopstock T, Tricta F, Neumayr L, Karin I, Zorzi G, Fradette C, Kmiec T, Büchner B, Steele HE, Horvath R, Chinnery PF, Basu A, Küpper C, Neuhofer C, Kálmán B, Dušek P, Yapici Z, Wilson I, Zhao F, …
• A Phase 3 Randomized Trial of Voxelotor in Sickle Cell Disease.
  The New England journal of medicine 2019 Vichinsky E, Hoppe CC, Ataga KI, Ware RE, Nduba V, El-Beshlawy A, Hassab H, Achebe MM, Alkindi S, Brown RC, Diuguid DL, Telfer P, Tsitsikas DA, Elghandour A, Gordeuk VR, Kanter J, Abboud MR, Lehrer-…
• Vincristine-induced anemia in hereditary spherocytosis.
  Experimental biology and medicine (Maywood, N.J.) 2019 Michlitsch J, Larkin S, Vichinsky E, Kuypers FA
• Evaluation of Mandible Fractures in Patients With Sickle Cell Anemia-A Nationwide Study.
  Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons 2019 Akbari M, Patel R, Carrao V, Hagar W, Vichinsky E, Chuang SK
• Transfusion practices and complications in thalassemia.
  Transfusion 2018 Lal A, Wong TE, Andrews J, Balasa VV, Chung JH, Forester CM, Ikeda AK, Keel SB, Pagano MB, Puthenveetil G, Shah SJ, Yu JC, Vichinsky EP
• A Phase 3 Trial of l-Glutamine in Sickle Cell Disease.
  The New England journal of medicine 2018 Niihara Y, Miller ST, Kanter J, Lanzkron S, Smith WR, Hsu LL, Gordeuk VR, Viswanathan K, Sarnaik S, Osunkwo I, Guillaume E, Sadanandan S, Sieger L, Lasky JL, Panosyan EH, Blake OA, New TN, Bellevue R,…
• Gene Therapy in Patients with Transfusion-Dependent β-Thalassemia.
  The New England journal of medicine 2018 Thompson AA, Walters MC, Kwiatkowski J, Rasko JEJ, Ribeil JA, Hongeng S, Magrin E, Schiller GJ, Payen E, Semeraro M, Moshous D, Lefrere F, Puy H, Bourget P, Magnani A, Caccavelli L, Diana JS, Suarez F…
• Epidemiologic and clinical characteristics of nontransfusion-dependent thalassemia in the United States.
  Pediatric blood & cancer 2018 Vichinsky E, Cohen A, Thompson AA, Giardina PJ, Lal A, Paley C, Cheng WY, McCormick N, Sasane M, Qiu Y, Kwiatkowski JL
• Fertility and Pregnancy in Women with Transfusion-Dependent Thalassemia.
  Hematology/oncology clinics of North America 2018 Carlberg KT, Singer ST, Vichinsky EP
• Sickle cell disease.
  Nature reviews. Disease primers 2018 Kato GJ, Piel FB, Reid CD, Gaston MH, Ohene-Frempong K, Krishnamurti L, Smith WR, Panepinto JA, Weatherall DJ, Costa FF, Vichinsky EP
• Dietary nonheme iron is equally bioavailable from ferritin or ferrous sulfate in thalassemia intermedia.
  Pediatric hematology and oncology 2017 Khurana M, Fung EB, Vichinsky EP, Theil EC
• Chronic organ failure in adult sickle cell disease.
  Hematology. American Society of Hematology. Education Program 2017 Vichinsky E
• Variability of homozygous sickle cell disease: The role of alpha and beta globin chain variation and other factors.
  Blood cells, molecules & diseases 2017 Serjeant GR, Vichinsky E
• Encephaloduroarteriosynangiosis (EDAS) in young patients with cerebrovascular complications of sickle cell disease: Single-institution experience.
  Pediatric hematology and oncology 2017 Winstead M, Sun PP, Martin K, Earl J, Neumayr L, Hoppe C, Vichinsky E
• Lifespan care in SCD: Whom to transition, the patients or the health care system?
  American journal of hematology 2017 Minniti CP, Vichinsky E
• Simvastatin reduces vaso-occlusive pain in sickle cell anaemia: a pilot efficacy trial.
  British journal of haematology 2017 Hoppe C, Jacob E, Styles L, Kuypers F, Larkin S, Vichinsky E
• Long-term safety and efficacy of deferasirox in young pediatric patients with transfusional hemosiderosis: Results from a 5-year observational study (ENTRUST).
  Pediatric blood & cancer 2017 Vichinsky E, El-Beshlawy A, Al Zoebie A, Kamdem A, Koussa S, Chotsampancharoen T, Bruederle A, Gilotti G, Han J, Elalfy M
• NNKTT120, an anti-iNKT cell monoclonal antibody, produces rapid and sustained iNKT cell depletion in adults with sickle cell disease.
  PloS one 2017 Field JJ, Majerus E, Ataga KI, Vichinsky EP, Schaub R, Mashal R, Nathan DG
• Emergency department utilization by Californians with sickle cell disease, 2005-2014.
  Pediatric blood & cancer 2016 Paulukonis ST, Feuchtbaum LB, Coates TD, Neumayr LD, Treadwell MJ, Vichinsky EP, Hulihan MM
• Favorable outcomes after in utero transfusion in fetuses with alpha thalassemia major: a case series and review of the literature.
  Prenatal diagnosis 2016 Kreger EM, Singer ST, Witt RG, Sweeters N, Lianoglou B, Lal A, Mackenzie TC, Vichinsky E
• Stroke recurrence in adult sickle cell patients: it is time for action!
  Transfusion 2016 Neumayr L, Vichinsky E
• Non-transfusion-dependent thalassemia and thalassemia intermedia: epidemiology, complications, and management.
  Current medical research and opinion 2015 Vichinsky E
• Fertility in transfusion-dependent thalassemia men: effects of iron burden on the reproductive axis.
  American journal of hematology 2015 Singer ST, Killilea D, Suh JH, Wang ZJ, Yuan Q, Ivani K, Evans P, Vichinsky E, Fischer R, Smith JF
• Dysregulated arginine metabolism and cardiopulmonary dysfunction in patients with thalassaemia.
  British journal of haematology 2015 Morris CR, Kim HY, Klings ES, Wood J, Porter JB, Trachtenberg F, Sweeters N, Olivieri NF, Kwiatkowski JL, Virzi L, Hassell K, Taher A, Neufeld EJ, Thompson AA, Larkin S, Suh JH, Vichinsky EP, Kuypers …
• Is the medical home for adult patients with sickle cell disease a reality or an illusion?
  Hemoglobin 2015 Ballas SK, Vichinsky EP
• In utero hematopoietic cell transplantation for hemoglobinopathies.
  Frontiers in pharmacology 2015 Derderian SC, Jeanty C, Walters MC, Vichinsky E, MacKenzie TC
• Mechanisms of plasma non-transferrin bound iron generation: insights from comparing transfused diamond blackfan anaemia with sickle cell and thalassaemia patients.
  British journal of haematology 2014 Porter JB, Walter PB, Neumayr LD, Evans P, Bansal S, Garbowski M, Weyhmiller MG, Harmatz PR, Wood JC, Miller JL, Byrnes C, Weiss G, Seifert M, Grosse R, Grabowski D, Schmidt A, Fischer R, Nielsen P, …
• Population based surveillance in sickle cell disease: methods, findings and implications from the California registry and surveillance system in hemoglobinopathies project (RuSH).
  Pediatric blood & cancer 2014 Paulukonis ST, Harris WT, Coates TD, Neumayr L, Treadwell M, Vichinsky E, Feuchtbaum LB
• Emerging Therapies Targeting the Pathophysiology of Sickle Cell Disease
  Hematology/Oncology Clinics of North America 2014 Vichinsky, Elliott P., ed.
• Relationship among chelator adherence, change in chelators, and quality of life in thalassemia.
  Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation 2014 Trachtenberg FL, Gerstenberger E, Xu Y, Mednick L, Sobota A, Ware H, Thompson AA, Neufeld EJ, Yamashita R, Thalassemia Clinical Research Network
• Elevated tricuspid regurgitant jet velocity in subgroups of thalassemia patients: insight into pathophysiology and the effect of splenectomy.
  Annals of hematology 2014 Singer ST, Kuypers F, Fineman J, Gildengorin G, Larkin S, Sweeters N, Rosenfeld H, Kurio G, Higa A, Jeng M, Huang J, Vichinsky EP
• Neuroimaging abnormalities in adults with sickle cell anemia: associations with cognition.
  Neurology 2014 Mackin RS, Insel P, Truran D, Vichinsky EP, Neumayr LD, Armstrong FD, Gold JI, Kesler K, Brewer J, Weiner MW, Neuropsychological Dysfunction and Neuroimaging Adult Sickle Cell Anemia Study Group
• Response to "efficacy and safety of sildenafil for the treatment of severe pulmonary hypertension in patients with hemoglobinopathies: results from a long-term follow up " Haematologica 2014;99(2):e17-18.
  Haematologica 2014 Klings ES, Vichinsky EP, Morris CR
• Validation and reliability of a disease-specific quality of life measure (the TranQol) in adults and children with thalassaemia major.
  British journal of haematology 2013 Klaassen RJ, Barrowman N, Merelles-Pulcini M, Vichinsky EP, Sweeters N, Kirby-Allen M, Neufeld EJ, Kwiatkowski JL, Wu J, Vickars L, Blanchette VS, Forgie M, Yamashita R, Wong-Rieger D, Young NL
• Pain over time and its effects on life in thalassemia.
  American journal of hematology 2013 Oliveros O, Trachtenberg F, Haines D, Gerstenberger E, Martin M, Carson S, Green S, Calamaras D, Hess P, Yamashita R, Vichinsky E, Thalassemia Clinical Research Network
• Renal medullary carcinoma in an adolescent with sickle cell anemia.
  Pediatric blood & cancer 2013 Marsh A, Golden C, Hoppe C, Quirolo K, Vichinsky E
• Efficacy and safety of deferasirox compared with deferoxamine in sickle cell disease: two-year results including pharmacokinetics and concomitant hydroxyurea.
  American journal of hematology 2013 Vichinsky E, Torres M, Minniti CP, Barrette S, Habr D, Zhang Y, Files B, study CICL670A2201 investigators
• Zinc supplementation improves bone density in patients with thalassemia: a double-blind, randomized, placebo-controlled trial.
  The American journal of clinical nutrition 2013 Fung EB, Kwiatkowski JL, Huang JN, Gildengorin G, King JC, Vichinsky EP
• Treatment of classic pantothenate kinase-associated neurodegeneration with deferiprone and intrathecal baclofen.
  American journal of physical medicine & rehabilitation 2013 Pratini NR, Sweeters N, Vichinsky E, Neufeld JA
• Transfusion complications in thalassemia patients: a report from the Centers for Disease Control and Prevention (CME).
  Transfusion 2013 Vichinsky E, Neumayr L, Trimble S, Giardina PJ, Cohen AR, Coates T, Boudreaux J, Neufeld EJ, Kenney K, Grant A, Thompson AA, CDC Thalassemia Investigators
• Pregnancy outcomes in women with thalassemia in North America and the United Kingdom.
  American journal of hematology 2013 Thompson AA, Kim HY, Singer ST, Vichinsky E, Eile J, Yamashita R, Giardina PJ, Olivieri N, Parmar N, Trachtenberg F, Neufeld EJ, Kwiatkowski JL, Thalassemia Clinical Research Network
• Non-transfusion-dependent thalassemias.
  Haematologica 2013 Musallam KM, Rivella S, Vichinsky E, Rachmilewitz EA
• Treatment of heart failure in adults with thalassemia major: response in patients randomised to deferoxamine with or without deferiprone.
  Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance 2013 Porter JB, Wood J, Olivieri N, Vichinsky EP, Taher A, Neufeld E, Giardina P, Thompson A, Moore B, Evans P, Kim HY, Macklin EA, Trachtenberg F
• A randomized, placebo-controlled trial of arginine therapy for the treatment of children with sickle cell disease hospitalized with vaso-occlusive pain episodes.
  Haematologica 2013 Morris CR, Kuypers FA, Lavrisha L, Ansari M, Sweeters N, Stewart M, Gildengorin G, Neumayr L, Vichinsky EP
• Clinical manifestations of α-thalassemia.
  Cold Spring Harbor perspectives in medicine 2013 Vichinsky EP
• The palatability and tolerability of deferasirox taken with different beverages or foods.
  Pediatric blood & cancer 2013 Goldberg SL, Giardina PJ, Chirnomas D, Esposito J, Paley C, Vichinsky E
• Sildenafil therapy in thalassemia patients with Doppler-defined risk of pulmonary hypertension.
  Haematologica 2013 Morris CR, Kim HY, Wood J, Porter JB, Klings ES, Trachtenberg FL, Sweeters N, Olivieri NF, Kwiatkowski JL, Virzi L, Singer ST, Taher A, Neufeld EJ, Thompson AA, Sachdev V, Larkin S, Suh JH, Kuypers FA…
• Application of multiplex ligation-dependent probe amplification to screen for β-globin cluster deletions: detection of two novel deletions in a multi ethnic population.
  Hemoglobin 2013 Cui J, Azimi M, Baysdorfer C, Vichinsky EP, Hoppe CC
• Human T cell lymphotropic virus type 1 infection among U.S. thalassemia patients.
  AIDS research and human retroviruses 2013 Switzer WM, Shankar A, Trimble SR, Thompson AA, Giardina PJ, Cohen AR, Coates TD, Vichinsky E, Neufeld EJ, Boudreaux JM, Heneine W
• Pain in thalassaemia: the effects of age on pain frequency and severity.
  British journal of haematology 2012 Haines D, Martin M, Carson S, Oliveros O, Green S, Coates T, Eile J, Schilling L, Dinu B, Mendoza T, Gerstenberger E, Trachtenberg F, Vichinsky E, Thalassemia Clinical Research Network
• Increased leucocyte apoptosis in transfused β-thalassaemia patients.
  British journal of haematology 2012 Walter PB, Porter J, Evans P, Kwiatkowski JL, Neufeld EJ, Coates T, Giardina PJ, Grady RW, Vichinsky E, Olivieri N, Trachtenberg F, Alberti D, Fung E, Ames B, Higa A, Harmatz P, Thalassemia Clinical …
• Combined chelation therapy with deferasirox and deferoxamine in thalassemia.
  Blood cells, molecules & diseases 2012 Lal A, Porter J, Sweeters N, Ng V, Evans P, Neumayr L, Kurio G, Harmatz P, Vichinsky E
• A phase 1/2 trial of HQK-1001, an oral fetal globin inducer, in sickle cell disease.
  American journal of hematology 2012 Kutlar A, Ataga K, Reid M, Vichinsky EP, Neumayr L, Blair-Britt L, Labotka R, Glass J, Keefer JR, Wargin WA, Berenson R, Perrine SP
• The effect of whole body vibration therapy on bone density in patients with thalassemia: a pilot study.
  American journal of hematology 2012 Fung EB, Gariepy CA, Sawyer AJ, Higa A, Vichinsky EP
• Inadequate dietary intake in patients with thalassemia.
  Journal of the Academy of Nutrition and Dietetics 2012 Fung EB, Xu Y, Trachtenberg F, Odame I, Kwiatkowski JL, Neufeld EJ, Thompson AA, Boudreaux J, Quinn CT, Vichinsky EP, Thalassemia Clinical Research Network
• Lower alloimmunization rates in pediatric sickle cell patients on chronic erythrocytapheresis compared to chronic simple transfusions.
  Transfusion 2012 Wahl SK, Garcia A, Hagar W, Gildengorin G, Quirolo K, Vichinsky E
• A potent oral P-selectin blocking agent improves microcirculatory blood flow and a marker of endothelial cell injury in patients with sickle cell disease.
  American journal of hematology 2012 Kutlar A, Ataga KI, McMahon L, Howard J, Galacteros F, Hagar W, Vichinsky E, Cheung AT, Matsui N, Embury SH
• Advances in the treatment of alpha-thalassemia.
  Blood reviews 2012 Vichinsky E
• Identification of three novel Hb F variants: Hb F-Hayward [Gγ1(NA1)Gly→Asp, GGT>GAT], Hb F-Chori-I [AγT16(A13)Gly→Asp, GGC>GAC] and Hb F-Chori-II [AγI29(B11)Gly→Glu, GGA>GAA].
  Hemoglobin 2012 Cui J, Baysdorfer C, Azimi M, Vichinsky EP, Hoppe CC
• Silent cerebral infarcts: a review on a prevalent and progressive cause of neurologic injury in sickle cell anemia.
  Blood 2012 DeBaun MR, Armstrong FD, McKinstry RC, Ware RE, Vichinsky E, Kirkham FJ
• British Journal of Haematology
  Safety of deferasirox in sickle cell disease patients with co-existing liver impairment – response to Sinakos et al 2012 Vichinsky E.
• Chelation use and iron burden in North American and British thalassemia patients: a report from the Thalassemia Longitudinal Cohort.
  Blood 2012 Kwiatkowski JL, Kim HY, Thompson AA, Quinn CT, Mueller BU, Odame I, Giardina PJ, Vichinsky EP, Boudreaux JM, Cohen AR, Porter JB, Coates T, Olivieri NF, Neufeld EJ, Thalassemia Clinical Research …
• Emerging 'A' therapies in hemoglobinopathies: agonists, antagonists, antioxidants, and arginine.
  Hematology. American Society of Hematology. Education Program 2012 Vichinsky E
• The prevention and management of alloimmunization in sickle cell disease: the benefit of extended phenotypic matching of red blood cells.
  Immunohematology 2012 Vichinsky EP
• Hb E/beta-thalassaemia: a common & clinically diverse disorder.
  The Indian journal of medical research 2011 Olivieri NF, Pakbaz Z, Vichinsky E
• Risk factors and mortality associated with an elevated tricuspid regurgitant jet velocity measured by Doppler-echocardiography in thalassemia: a Thalassemia Clinical Research Network report.
  Blood 2011 Morris CR, Kim HY, Trachtenberg F, Wood J, Quinn CT, Sweeters N, Kwiatkowski JL, Thompson AA, Giardina PJ, Boudreaux J, Olivieri NF, Porter JB, Neufeld EJ, Vichinsky EP, Thalassemia Clinical Research …
• Reproductive capacity in iron overloaded women with thalassemia major.
  Blood 2011 Singer ST, Vichinsky EP, Gildengorin G, van Disseldorp J, Rosen M, Cedars MI
• A pilot study of subcutaneous decitabine in β-thalassemia intermedia.
  Blood 2011 Olivieri NF, Saunthararajah Y, Thayalasuthan V, Kwiatkowski J, Ware RE, Kuypers FA, Kim HY, Trachtenberg FL, Vichinsky EP, Thalassemia Clinical Research Network
• Long-term safety and efficacy of deferasirox (Exjade) for up to 5 years in transfusional iron-overloaded patients with sickle cell disease.
  British journal of haematology 2011 Vichinsky E, Bernaudin F, Forni GL, Gardner R, Hassell K, Heeney MM, Inusa B, Kutlar A, Lane P, Mathias L, Porter J, Tebbi C, Wilson F, Griffel L, Deng W, Giannone V, Coates T
• Iron chelation adherence to deferoxamine and deferasirox in thalassemia.
  American journal of hematology 2011 Trachtenberg F, Vichinsky E, Haines D, Pakbaz Z, Mednick L, Sobota A, Kwiatkowski J, Thompson AA, Porter J, Coates T, Giardina PJ, Olivieri N, Yamashita R, Neufeld EJ, Thalassemia Clinical Research …
• Darbepoetin alfa for the treatment of anaemia in alpha- or beta- thalassaemia intermedia syndromes.
  British journal of haematology 2011 Singer ST, Vichinsky EP, Sweeters N, Rachmilewitz E
• A pilot study of the short-term use of simvastatin in sickle cell disease: effects on markers of vascular dysfunction.
  British journal of haematology 2011 Hoppe C, Kuypers F, Larkin S, Hagar W, Vichinsky E, Styles L
• Characterization of low bone mass in young patients with thalassemia by DXA, pQCT and markers of bone turnover.
  Bone 2011 Fung EB, Vichinsky EP, Kwiatkowski JL, Huang J, Bachrach LK, Sawyer AJ, Zemel BS
• The mediating effects of family functioning on psychosocial outcomes in healthy siblings of children with sickle cell disease.
  Pediatric blood & cancer 2011 Gold JI, Treadwell M, Weissman L, Vichinsky E
• Heterogeneity of hemoglobin H disease in childhood.
  The New England journal of medicine 2011 Lal A, Goldrich ML, Haines DA, Azimi M, Singer ST, Vichinsky EP
• Red cell alloimmunization in a diverse population of transfused patients with thalassaemia.
  British journal of haematology 2011 Thompson AA, Cunningham MJ, Singer ST, Neufeld EJ, Vichinsky E, Yamashita R, Giardina P, Kim HY, Trachtenberg F, Kwiatkowski JL, Thalassemia Clinical Research Network Investigators
• The effects of hydroxycarbamide and magnesium on haemoglobin SC disease: results of the multi-centre CHAMPS trial
  British Journal of Haematology 2011 Wang, W., Brugnara, C., Snyder, C., Wynn, L., Rogers, Z., Kalinyak, K., Brown, C., Qureshi, A., Bigelow, C., Neumayr, L., Smith-Whitley, K., Chui, D. H. K., Delahunty, M., Woolson, R., Steinberg, M., …
• Novel influenza A (H1N1) viral infection in pediatric patients with sickle-cell disease.
  Pediatric blood & cancer 2011 Jacobs JE, Quirolo K, Vichinsky E
• A phase 1 dose-escalation study: safety, tolerability, and pharmacokinetics of FBS0701, a novel oral iron chelator for the treatment of transfusional iron overload.
  Haematologica 2010 Rienhoff HY, Viprakasit V, Tay L, Harmatz P, Vichinsky E, Chirnomas D, Kwiatkowski JL, Tapper A, Kramer W, Porter JB, Neufeld EJ
• HbE/β-thalassemia: basis of marked clinical diversity.
  Hematology/oncology clinics of North America 2010 Olivieri NF, Pakbaz Z, Vichinsky E
• Chart Card: feasibility of a tool for improving emergency department care in sickle cell disease.
  Journal of the National Medical Association 2010 Neumayr L, Pringle S, Giles S, Quirolo KC, Paulukonis S, Vichinsky EP, Treadwell MJ
• Education and employment status of children and adults with thalassemia in North America.
  Pediatric blood & cancer 2010 Pakbaz Z, Treadwell M, Kim HY, Trachtenberg F, Parmar N, Kwiatkowski JL, Cunningham MJ, Martin M, Sweeters N, Neufeld EJ, Giardina PJ, Olivieri N, Yamashita RC, Vichinsky E
• Pulmonary hypertension and NO in sickle cell.
  Blood 2010 Gladwin MT, Barst RJ, Castro OL, Gordeuk VR, Hillery CA, Kato GJ, Kim-Shapiro DB, Machado R, Morris CR, Steinberg MH, Vichinsky EP
• Complexity of alpha thalassemia: growing health problem with new approaches to screening, diagnosis, and therapy.
  Annals of the New York Academy of Sciences 2010 Vichinsky E
• Fertility potential in thalassemia major women: current findings and future diagnostic tools.
  Annals of the New York Academy of Sciences 2010 Singer ST, Sweeters N, Vega O, Higa A, Vichinsky E, Cedars M
• Preface to Cooley's Anemia: Ninth Symposium.
  Annals of the New York Academy of Sciences 2010 Vichinsky EP, Neufeld EJ
• Pulmonary hypertension in thalassemia.
  Annals of the New York Academy of Sciences 2010 Morris CR, Vichinsky EP
• Approaches to transfusion therapy and iron overload in patients with sickle cell disease: results of an international survey.
  Pediatric hematology and oncology 2010 Vichinsky EP, Ohene-Frempong K, Transfusion Committee
• Transfusion and chelation practices in sickle cell disease: a regional perspective.
  Pediatric hematology and oncology 2010 Vichinsky EP, Ohene-Frempong K, Thein SL, Lobo CL, Inati A, Thompson AA, Smith-Whitley K, Kwiatkowski JL, Swerdlow PS, Porter JB, Marks PW
• Relationship between chronic transfusion therapy and body composition in subjects with thalassemia.
  The Journal of pediatrics 2010 Fung EB, Xu Y, Kwiatkowski JL, Vogiatzi MG, Neufeld E, Olivieri N, Vichinsky EP, Giardina PJ, Thalassemia Clinical Research Network
• Neuropsychological dysfunction and neuroimaging abnormalities in neurologically intact adults with sickle cell anemia.
  JAMA 2010 Vichinsky EP, Neumayr LD, Gold JI, Weiner MW, Rule RR, Truran D, Kasten J, Eggleston B, Kesler K, McMahon L, Orringer EP, Harrington T, Kalinyak K, De Castro LM, Kutlar A, Rutherford CJ, Johnson C, …
• Elevated exhaled carbon monoxide concentration in hemoglobinopathies and its relation to red blood cell transfusion therapy.
  Pediatric hematology and oncology 2010 James EB, Vreman HJ, Wong RJ, Stevenson DK, Vichinsky E, Schumacher L, Hall JY, Simon J, Golden DW, Harmatz P
• Pulmonary hypertension in hemolytic anemias.
  F1000 medicine reports 2010 Wahl S, Vichinsky E
• Hemoglobin Hakkari: an autosomal dominant form of beta thalassemia with inclusion bodies arising from de novo mutation in exon 2 of beta globin gene.
  Pediatric blood & cancer 2010 Kanathezhath B, Hazard FK, Guo H, Kidd J, Azimi M, Kuypers FA, Vichinsky EP, Lal A
• Assessment of cardiac iron by MRI susceptometry and R2* in patients with thalassemia.
  Magnetic resonance imaging 2010 Wang ZJ, Fischer R, Chu Z, Mahoney DH, Mueller BU, Muthupillai R, James EB, Krishnamurthy R, Chung T, Padua E, Vichinsky E, Harmatz P
• Low dose, oral epsilon aminocaproic acid for renal papillary necrosis and massive hemorrhage in hemoglobin SC disease.
  Pediatric blood & cancer 2010 Gabrovsky A, Aderinto A, Aderinto A, Spevak M, Vichinsky E, Resar LM
• Application of an expanded multiplex genotyping assay for the simultaneous detection of Hemoglobin Constant Spring and common deletional alpha-thalassemia mutations.
  International journal of laboratory hematology 2009 Kidd JL, Azimi M, Lubin B, Vichinsky E, Hoppe C
• Iron metabolism and iron chelation in sickle cell disease.
  Acta haematologica 2009 Walter PB, Harmatz P, Vichinsky E
• Hemoglobin H-constant spring in North America: an alpha thalassemia with frequent complications.
  American journal of hematology 2009 Singer ST, Kim HY, Olivieri NF, Kwiatkowski JL, Coates TD, Carson S, Neufeld E, Cunningham MJ, Giardina PJ, Mueller BU, Quinn CT, Fung E, Vichinsky E, Thalassemia Clinical Research Network
• Severe sickle cell disease--pathophysiology and therapy.
  Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2009 Buchanan G, Vichinsky E, Krishnamurti L, Shenoy S
• Efficacy and safety of deferasirox doses of >30 mg/kg per d in patients with transfusion-dependent anaemia and iron overload.
  British journal of haematology 2009 Taher A, Cappellini MD, Vichinsky E, Galanello R, Piga A, Lawniczek T, Clark J, Habr D, Porter JB
• Serum ferritin level changes in children with sickle cell disease on chronic blood transfusion are nonlinear and are associated with iron load and liver injury.
  Blood 2009 Adamkiewicz TV, Abboud MR, Paley C, Olivieri N, Kirby-Allen M, Vichinsky E, Casella JF, Alvarez OA, Barredo JC, Lee MT, Iyer RV, Kutlar A, McKie KM, McKie V, Odo N, Gee B, Kwiatkowski JL, Woods GM, …
• Differences in the prevalence of growth, endocrine and vitamin D abnormalities among the various thalassaemia syndromes in North America.
  British journal of haematology 2009 Vogiatzi MG, Macklin EA, Trachtenberg FL, Fung EB, Cheung AM, Vichinsky E, Olivieri N, Kirby M, Kwiatkowski JL, Cunningham M, Holm IA, Fleisher M, Grady RW, Peterson CM, Giardina PJ, Thalassemia …
• HLA type and risk of alloimmunization in sickle cell disease.
  American journal of hematology 2009 Hoppe C, Klitz W, Vichinsky E, Styles L
• Newborn screening for hemoglobinopathies in California.
  Pediatric blood & cancer 2009 Michlitsch J, Azimi M, Hoppe C, Walters MC, Lubin B, Lorey F, Vichinsky E
• Bone disease in thalassemia: a frequent and still unresolved problem.
  Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2009 Vogiatzi MG, Macklin EA, Fung EB, Cheung AM, Vichinsky E, Olivieri N, Kirby M, Kwiatkowski JL, Cunningham M, Holm IA, Lane J, Schneider R, Fleisher M, Grady RW, Peterson CC, Giardina PJ, Thalassemia …
• Alpha thalassemia major--new mutations, intrauterine management, and outcomes.
  Hematology. American Society of Hematology. Education Program 2009 Vichinsky EP
• Pulmonary complications of sickle cell disease.
  The New England journal of medicine 2008 Gladwin MT, Vichinsky E
• Hemoglobinopathies.
  Current molecular medicine 2008 Vichinsky E, Rodgers GP, Rachmilewitz E
• Hydroxycarbamide-induced changes in E/beta thalassemia red blood cells.
  American journal of hematology 2008 Singer ST, Vichinsky EP, Larkin S, Olivieri N, Sweeters N, Kuypers FA, E/beta Thalassemia Study Group
• Psychosocial and behavioral outcomes in children with sickle cell disease and their healthy siblings.
  Journal of behavioral medicine 2008 Gold JI, Mahrer NE, Treadwell M, Weissman L, Vichinsky E
• Safety and efficacy of pegylated interferon alpha-2a and ribavirin for the treatment of hepatitis C in patients with thalassemia.
  Haematologica 2008 Harmatz P, Jonas MM, Kwiatkowski JL, Wright EC, Fischer R, Vichinsky E, Giardina PJ, Neufeld EJ, Porter J, Olivieri N, Thalassemia Clinical Research Network
• Detection and assessment of stroke in patients with sickle cell disease: neuropsychological functioning and magnetic resonance imaging.
  Pediatric hematology and oncology 2008 Gold JI, Johnson CB, Treadwell MJ, Hans N, Vichinsky E
• Oral iron chelators and the treatment of iron overload in pediatric patients with chronic anemia.
  Pediatrics 2008 Vichinsky E
• Disparity in the management of iron overload between patients with sickle cell disease and thalassemia who received transfusions.
  Transfusion 2008 Fung EB, Harmatz PR, Milet M, Balasa V, Ballas SK, Casella JF, Hilliard L, Kutlar A, McClain KL, Olivieri NF, Porter JB, Vichinsky EP, Multi-Center Iron Overload Research Group
• An expanded Transactional Stress and Coping Model for siblings of children with sickle cell disease: family functioning and sibling coping, self-efficacy and perceived social support.
  Child: care, health and development 2008 Gold JI, Treadwell M, Weissman L, Vichinsky E
• Inflammation and oxidant-stress in beta-thalassemia patients treated with iron chelators deferasirox (ICL670) or deferoxamine: an ancillary study of the Novartis CICL670A0107 trial.
  Haematologica 2008 Walter PB, Macklin EA, Porter J, Evans P, Kwiatkowski JL, Neufeld EJ, Coates T, Giardina PJ, Vichinsky E, Olivieri N, Alberti D, Holland J, Harmatz P, Thalassemia Clinical Research Network
• Clinical application of deferasirox: practical patient management.
  American journal of hematology 2008 Vichinsky E
• Patient-reported outcomes of deferasirox (Exjade, ICL670) versus deferoxamine in sickle cell disease patients with transfusional hemosiderosis. Substudy of a randomized open-label phase II trial.
  Acta haematologica 2008 Vichinsky E, Pakbaz Z, Onyekwere O, Porter J, Swerdlow P, Coates T, Lane P, Files B, Mueller BU, Coïc L, Forni GL, Fischer R, Marks P, Rofail D, Abetz L, Baladi JF
• Fracture prevalence and relationship to endocrinopathy in iron overloaded patients with sickle cell disease and thalassemia.
  Bone 2008 Fung EB, Harmatz PR, Milet M, Coates TD, Thompson AA, Ranalli M, Mignaca R, Scher C, Giardina P, Robertson S, Neumayr L, Vichinsky EP, Multi-Center Iron Overload Study Group
• Advances in clinical research in sickle cell disease.
  British journal of haematology 2008 Hagar W, Vichinsky E
• Transfusional iron burden and liver toxicity after bone marrow transplantation for acute myelogenous leukemia and hemoglobinopathies.
  Pediatric blood & cancer 2008 Jastaniah W, Harmatz P, Pakbaz Z, Fischer R, Vichinsky E, Walters MC
• Efficacy and safety of the Gardos channel blocker, senicapoc (ICA-17043), in patients with sickle cell anemia.
  Blood 2008 Ataga KI, Smith WR, De Castro LM, Swerdlow P, Saunthararajah Y, Castro O, Vichinsky E, Kutlar A, Orringer EP, Rigdon GC, Stocker JW, ICA-17043-05 Investigators
• Ethical issues and risk/benefit assessment of iron chelation therapy: advances with deferiprone/deferoxamine combinations and concerns about the safety, efficacy and costs of deferasirox [Kontoghiorghes GJ, Hemoglobin 2008; 32(1-2):1-15.].
  Hemoglobin 2008 Porter JB, Taher AT, Cappellini MD, Vichinsky EP
• Relative response of patients with myelodysplastic syndromes and other transfusion-dependent anaemias to deferasirox (ICL670): a 1-yr prospective study.
  European journal of haematology 2007 Porter J, Galanello R, Saglio G, Neufeld EJ, Vichinsky E, Cappellini MD, Olivieri N, Piga A, Cunningham MJ, Soulières D, Gattermann N, Tchernia G, Maertens J, Giardina P, Kwiatkowski J, Quarta G, Jeng…
• Clinical differences between children and adults with pulmonary hypertension and sickle cell disease.
  British journal of haematology 2007 Hagar RW, Michlitsch JG, Gardner J, Vichinsky EP, Morris CR
• Erythrocyte glutamine depletion, altered redox environment, and pulmonary hypertension in sickle cell disease.
  Blood 2007 Morris CR, Suh JH, Hagar W, Larkin S, Bland DA, Steinberg MH, Vichinsky EP, Shigenaga M, Ames B, Kuypers FA, Klings ES
• Serum ferritin underestimates liver iron concentration in transfusion independent thalassemia patients as compared to regularly transfused thalassemia and sickle cell patients.
  Pediatric blood & cancer 2007 Pakbaz Z, Fischer R, Fung E, Nielsen P, Harmatz P, Vichinsky E
• Phase Ib clinical trial of starch-conjugated deferoxamine (40SD02): a novel long-acting iron chelator.
  British journal of haematology 2007 Harmatz P, Grady RW, Dragsten P, Vichinsky E, Giardina P, Madden J, Jeng M, Miller B, Hanson G, Hedlund B
• Iron homeostasis during transfusional iron overload in beta-thalassemia and sickle cell disease: changes in iron regulatory protein, hepcidin, and ferritin expression.
  Pediatric hematology and oncology 2007 Jenkins ZA, Hagar W, Bowlus CL, Johansson HE, Harmatz P, Vichinsky EP, Theil EC
• Prospective evaluation of patient-reported outcomes during treatment with deferasirox or deferoxamine for iron overload in patients with beta-thalassemia.
  Clinical therapeutics 2007 Cappellini MD, Bejaoui M, Agaoglu L, Porter J, Coates T, Jeng M, Lai ME, Mangiagli A, Strauss G, Girot R, Watman N, Ferster A, Loggetto S, Abish S, Cario H, Zoumbos N, Vichinsky E, Opitz H, Ressayre-…
• Morbidity and mortality in chronically transfused subjects with thalassemia and sickle cell disease: A report from the multi-center study of iron overload.
  American journal of hematology 2007 Fung EB, Harmatz P, Milet M, Ballas SK, De Castro L, Hagar W, Owen W, Olivieri N, Smith-Whitley K, Darbari D, Wang W, Vichinsky E, Multi-Center Study of Iron Overload Research Group
• A randomised comparison of deferasirox versus deferoxamine for the treatment of transfusional iron overload in sickle cell disease.
  British journal of haematology 2007 Vichinsky E, Onyekwere O, Porter J, Swerdlow P, Eckman J, Lane P, Files B, Hassell K, Kelly P, Wilson F, Bernaudin F, Forni GL, Okpala I, Ressayre-Djaffer C, Alberti D, Holland J, Marks P, Fung E, …
• Caregiving time in sickle cell disease: psychological effects in maternal caregivers.
  Pediatric blood & cancer 2007 Moskowitz JT, Butensky E, Harmatz P, Vichinsky E, Heyman MB, Acree M, Wrubel J, Wilson L, Folkman S
• Hemoglobin e syndromes.
  Hematology. American Society of Hematology. Education Program 2007 Vichinsky E
• Bone mineral density in children with sickle cell anemia.
  Pediatric blood & cancer 2006 Lal A, Fung EB, Pakbaz Z, Hackney-Stephens E, Vichinsky EP
• Physical therapy alone compared with core decompression and physical therapy for femoral head osteonecrosis in sickle cell disease. Results of a multicenter study at a mean of three years after treatment.
  The Journal of bone and joint surgery. American volume 2006 Neumayr LD, Aguilar C, Earles AN, Jergesen HE, Haberkern CM, Kammen BF, Nancarrow PA, Padua E, Milet M, Stulberg BN, Williams RA, Orringer EP, Graber N, Robertson SM, Vichinsky EP, National …
• Dose-escalation study of ICA-17043 in patients with sickle cell disease.
  Pharmacotherapy 2006 Ataga KI, Orringer EP, Styles L, Vichinsky EP, Swerdlow P, Davis GA, Desimone PA, Stocker JW
• Increased prevalence of iron-overload associated endocrinopathy in thalassaemia versus sickle-cell disease.
  British journal of haematology 2006 Fung EB, Harmatz PR, Lee PD, Milet M, Bellevue R, Jeng MR, Kalinyak KA, Hudes M, Bhatia S, Vichinsky EP, Multi-Centre Study of Iron Overload Research Group
• Oxidative stress and inflammation in iron-overloaded patients with beta-thalassaemia or sickle cell disease.
  British journal of haematology 2006 Walter PB, Fung EB, Killilea DW, Jiang Q, Hudes M, Madden J, Porter J, Evans P, Vichinsky E, Harmatz P
• Prevalence of HFE mutations in California newborns.
  Pediatric hematology and oncology 2006 Hoppe C, Watson RM, Long CM, Lorey F, Robles L, Klitz W, Styles L, Vichinsky E
• Pulmonary hypertension in thalassemia: association with platelet activation and hypercoagulable state.
  American journal of hematology 2006 Singer ST, Kuypers FA, Styles L, Vichinsky EP, Foote D, Rosenfeld H
• Pulmonary hypertension in thalassaemia major patients with normal left ventricular systolic function.
  British journal of haematology 2006 Hagar RW, Morris CR, Vichinsky EP
• Using qualitative and quantitative strategies to evaluate knowledge and perceptions about sickle cell disease and sickle cell trait.
  Journal of the National Medical Association 2006 Treadwell MJ, McClough L, Vichinsky E
• Prevalence of fractures among the Thalassemia syndromes in North America.
  Bone 2005 Vogiatzi MG, Macklin EA, Fung EB, Vichinsky E, Olivieri N, Kwiatkowski J, Cohen A, Neufeld E, Giardina PJ
• Changes in the epidemiology of thalassemia in North America: a new minority disease.
  Pediatrics 2005 Vichinsky EP, MacKlin EA, Waye JS, Lorey F, Olivieri NF
• Fetal haemoglobin augmentation in E/beta(0) thalassaemia: clinical and haematological outcome.
  British journal of haematology 2005 Singer ST, Kuypers FA, Olivieri NF, Weatherall DJ, Mignacca R, Coates TD, Davies S, Sweeters N, Vichinsky EP, E/beta Thalassaemia Study Group
• Bone and joint disease in sickle cell disease.
  Hematology/oncology clinics of North America 2005 Aguilar C, Vichinsky E, Neumayr L
• Comparison of organ dysfunction in transfused patients with SCD or beta thalassemia.
  American journal of hematology 2005 Vichinsky E, Butensky E, Fung E, Hudes M, Theil E, Ferrell L, Williams R, Louie L, Lee PD, Harmatz P
• Dysregulated arginine metabolism, hemolysis-associated pulmonary hypertension, and mortality in sickle cell disease.
  JAMA 2005 Morris CR, Kato GJ, Poljakovic M, Wang X, Blackwelder WC, Sachdev V, Hazen SL, Vichinsky EP, Morris SM, Gladwin MT
• Clinical evaluation of avascular necrosis in patients with sickle cell disease: Children's Hospital Oakland Hip Evaluation Scale--a modification of the Harris Hip Score.
  Archives of physical medicine and rehabilitation 2005 Aguilar CM, Neumayr LD, Eggleston BE, Earles AN, Robertson SM, Jergesen HE, Stulberg BN, Vichinsky EP
• Barriers to adherence of deferoxamine usage in sickle cell disease.
  Pediatric blood & cancer 2005 Treadwell MJ, Law AW, Sung J, Hackney-Stephens E, Quirolo K, Murray E, Glendenning GA, Vichinsky E
• A simple model to assess and improve adherence to iron chelation therapy with deferoxamine in patients with thalassemia.
  Annals of the New York Academy of Sciences 2005 Pakbaz Z, Fischer R, Treadwell M, Yamashita R, Fung EB, Calvelli L, Quirolo K, Foote D, Harmatz P, Vichinsky EP
• Changing patterns of thalassemia worldwide.
  Annals of the New York Academy of Sciences 2005 Vichinsky EP
• Hemoglobin E-beta-thalassemia: Progress report from the International Study Group.
  Annals of the New York Academy of Sciences 2005 Premawardhena A, De Silver S, Arambepola M, Olivieri NF, Vichinsky EP, Merson L, Muraco G, Allen A, Fisher C, Peto T, Weatherall DJ
• Hemolysis-associated pulmonary hypertension in thalassemia.
  Annals of the New York Academy of Sciences 2005 Morris CR, Kuypers FA, Kato GJ, Lavrisha L, Larkin S, Singer T, Vichinsky EP
• Measuring chromosome breaks in patients with thalassemia.
  Annals of the New York Academy of Sciences 2005 Offer T, Bhagat A, Lal A, Atamna W, Singer ST, Vichinsky EP, Kuypers FA, Ames BN
• Outcomes of preimplantation genetic diagnosis therapy in treatment of beta-thalassemia: A retrospective analysis.
  Annals of the New York Academy of Sciences 2005 Qureshi N, Foote D, Walters MC, Singer ST, Quirolo K, Vichinsky EP
• Quality of life in patients with thalassemia intermedia compared to thalassemia major.
  Annals of the New York Academy of Sciences 2005 Pakbaz Z, Treadwell M, Yamashita R, Quirolo K, Foote D, Quill L, Singer T, Vichinsky EP
• Single and combination drug therapy for fetal hemoglobin augmentation in hemoglobin E-beta 0-thalassemia: Considerations for treatment.
  Annals of the New York Academy of Sciences 2005 Singer ST, Kuypers FA, Olivieri NF, Weatherall DJ, Mignacca R, Coates TD, Davies S, Sweeters N, Vichinsky EP
• Treatment of hepatitis C virus infection in thalassemia.
  Annals of the New York Academy of Sciences 2005 Butensky E, Pakbaz Z, Foote D, Walters MC, Vichinsky EP, Harmatz P
• Utility of Holter electrocardiogram in iron-overloaded hemoglobinopathies.
  Annals of the New York Academy of Sciences 2005 Qureshi N, Avasarala K, Foote D, Vichinsky EP
• Variability in hepatic iron concentration in percutaneous needle biopsy specimens from patients with transfusional hemosiderosis.
  American journal of clinical pathology 2005 Butensky E, Fischer R, Hudes M, Schumacher L, Williams R, Moyer TP, Vichinsky E, Harmatz P
• Hematologic problems in immigrants from Southeast Asia.
  Hematology/oncology clinics of North America 2004 Jeng MR, Vichinsky E
• The new SQUID biosusceptometer at Oakland: first year of experience.
  Neurology & clinical neurophysiology : NCN 2004 Fung EB, Fischer R, Pakbaz Z, Fagaly RL, Vichinsky E, Starr TN, Ewing T, Paulson DN, Hassenzahl WV, Harmatz P
• Can peak systolic velocities be used for prediction of stroke in sickle cell anemia?
  Pediatric radiology 2004 Jones A, Granger S, Brambilla D, Gallagher D, Vichinsky E, Woods G, Berman B, Roach S, Nichols F, Adams RJ
• Thalassemia in Sri Lanka: a progress report.
  Human molecular genetics 2004 Premawardhena A, De Silva S, Arambepola M, Olivieri N, Merson L, Muraco J, Allen A, Fisher C, Peto T, Vichinsky E, Weatherall D
• The role of fetal hemoglobin-enhancing agents in thalassemia.
  Seminars in hematology 2004 Lal A, Vichinsky E
• Pulmonary hypertension in sickle cell disease.
  The New England journal of medicine 2004 Vichinsky EP
• Stroke and conversion to high risk in children screened with transcranial Doppler ultrasound during the STOP study.
  Blood 2004 Adams RJ, Brambilla DJ, Granger S, Gallagher D, Vichinsky E, Abboud MR, Pegelow CH, Woods G, Rohde EM, Nichols FT, Jones A, Luden JP, Bowman L, Hagner S, Morales KH, Roach ES, STOP Study
• Thalassemia.
  Hematology. American Society of Hematology. Education Program 2004 Cohen AR, Galanello R, Pennell DJ, Cunningham MJ, Vichinsky E
• Managing sickle cell disease.
  BMJ (Clinical research ed.) 2003 Claster S, Vichinsky EP
• Gene interactions and stroke risk in children with sickle cell anemia.
  Blood 2003 Hoppe C, Klitz W, Cheng S, Apple R, Steiner L, Robles L, Girard T, Vichinsky E, Styles L, CSSCD Investigators
• Invasive pneumococcal infections in children with sickle cell disease in the era of penicillin prophylaxis, antibiotic resistance, and 23-valent pneumococcal polysaccharide vaccination.
  The Journal of pediatrics 2003 Adamkiewicz TV, Sarnaik S, Buchanan GR, Iyer RV, Miller ST, Pegelow CH, Rogers ZR, Vichinsky E, Elliott J, Facklam RR, O'Brien KL, Schwartz B, Van Beneden CA, Cannon MJ, Eckman JR, Keyserling H, …
• Hydroxyurea and arginine therapy: impact on nitric oxide production in sickle cell disease.
  Journal of pediatric hematology/oncology 2003 Morris CR, Vichinsky EP, van Warmerdam J, Machado L, Kepka-Lenhart D, Morris SM, Kuypers FA
• Mycoplasma disease and acute chest syndrome in sickle cell disease.
  Pediatrics 2003 Neumayr L, Lennette E, Kelly D, Earles A, Embury S, Groncy P, Grossi M, Grover R, McMahon L, Swerdlow P, Waldron P, Vichinsky E
• Deferiprone and hepatic fibrosis.
  Blood 2003 Brittenham GM, Nathan DG, Olivieri NF, Porter JB, Pippard M, Vichinsky EP, Weatherall DJ
• Effect of hydroxyurea on mortality and morbidity in adult sickle cell anemia: risks and benefits up to 9 years of treatment.
  JAMA 2003 Steinberg MH, Barton F, Castro O, Pegelow CH, Ballas SK, Kutlar A, Orringer E, Bellevue R, Olivieri N, Eckman J, Varma M, Ramirez G, Adler B, Smith W, Carlos T, Ataga K, DeCastro L, Bigelow C, …
• Liver ferritin subunit ratios in neonatal hemochromatosis.
  Pediatric hematology and oncology 2003 Hagar W, Vichinsky EP, Theil EC
• Arginine therapy: a new treatment for pulmonary hypertension in sickle cell disease?
  American journal of respiratory and critical care medicine 2003 Morris CR, Morris SM, Hagar W, Van Warmerdam J, Claster S, Kepka-Lenhart D, Machado L, Kuypers FA, Vichinsky EP
• Chlamydia pneumoniae and acute chest syndrome in patients with sickle cell disease.
  Journal of pediatric hematology/oncology 2003 Dean D, Neumayr L, Kelly DM, Ballas SK, Kleman K, Robertson S, Iyer RV, Ware RE, Koshy M, Rackoff WR, Pegelow CH, Waldron P, Benjamin L, Vichinsky E, Acute Chest Syndrome Study Group
• Distinct HLA associations by stroke subtype in children with sickle cell anemia.
  Blood 2002 Hoppe C, Klitz W, Noble J, Vigil L, Vichinsky E, Styles L
• Pancytopenia induced by hypothermia.
  Journal of pediatric hematology/oncology 2002 Lo L, Singer ST, Vichinsky E
• Diseases of iron metabolism.
  Pediatric clinics of North America 2002 Hagar W, Theil EC, Vichinsky EP
• New therapies in sickle cell disease.
  Lancet (London, England) 2002 Vichinsky E
• Bioelectrical impedance analysis of the body composition of children and adolescents with sickle cell disease.
  The Journal of pediatrics 2002 VanderJagt DJ, Harmatz P, Scott-Emuakpor AB, Vichinsky E, Glew RH
• Longitudinal changes in ferritin during chronic transfusion: a report from the Stroke Prevention Trial in Sickle Cell Anemia (STOP).
  Journal of pediatric hematology/oncology 2002 Files B, Brambilla D, Kutlar A, Miller S, Vichinsky E, Wang W, Granger S, Adams RJ
• Longitudinal changes in brain magnetic resonance imaging findings in children with sickle cell disease.
  Blood 2002 Pegelow CH, Macklin EA, Moser FG, Wang WC, Bello JA, Miller ST, Vichinsky EP, DeBaun MR, Guarini L, Zimmerman RA, Younkin DP, Gallagher DM, Kinney TR
• Assessment of sickle cell pain in children and young adults using the adolescent pediatric pain tool.
  Journal of pain and symptom management 2002 Franck LS, Treadwell M, Jacob E, Vichinsky E
• Central venous catheter complications in sickle cell disease.
  American journal of hematology 2002 Jeng MR, Feusner J, Skibola C, Vichinsky E
• Effect of hydroxyurea on growth in children with sickle cell anemia: results of the HUG-KIDS Study.
  The Journal of pediatrics 2002 Wang WC, Helms RW, Lynn HS, Redding-Lallinger R, Gee BE, Ohene-Frempong K, Smith-Whitley K, Waclawiw MA, Vichinsky EP, Styles LA, Ware RE, Kinney TR
• Using quality improvement strategies to enhance pediatric pain assessment.
  International journal for quality in health care : journal of the International Society for Quality in Health Care 2002 Treadwell MJ, Franck LS, Vichinsky E
• Novel therapeutic approaches in sickle cell disease.
  Hematology. American Society of Hematology. Education Program 2002 Walters MC, Nienhuis AW, Vichinsky E
• Silent infarcts in children with sickle cell anemia and abnormal cerebral artery velocity.
  Archives of neurology 2001 Pegelow CH, Wang W, Granger S, Hsu LL, Vichinsky E, Moser FG, Bello J, Zimmerman RA, Adams RJ, Brambilla D, STOP Trial
• A novel multilocus genotyping assay to identify genetic predictors of stroke in sickle cell anaemia.
  British journal of haematology 2001 Hoppe C, Cheng S, Grow M, Silbergleit A, Klitz W, Trachtenberg E, Erlich H, Vichinsky E, Styles L
• Neuropsychologic performance in school-aged children with sickle cell disease: a report from the Cooperative Study of Sickle Cell Disease.
  The Journal of pediatrics 2001 Wang W, Enos L, Gallagher D, Thompson R, Guarini L, Vichinsky E, Wright E, Zimmerman R, Armstrong FD, Cooperative Study of Sickle Cell Disease
• Prospective RBC phenotype matching in a stroke-prevention trial in sickle cell anemia: a multicenter transfusion trial.
  Transfusion 2001 Vichinsky EP, Luban NL, Wright E, Olivieri N, Driscoll C, Pegelow CH, Adams RJ, Stroke Prevention Trail in Sickle Cell Anemia
• Silent infarction as a risk factor for overt stroke in children with sickle cell anemia: a report from the Cooperative Study of Sickle Cell Disease.
  The Journal of pediatrics 2001 Miller ST, Macklin EA, Pegelow CH, Kinney TR, Sleeper LA, Bello JA, DeWitt LD, Gallagher DM, Guarini L, Moser FG, Ohene-Frempong K, Sanchez N, Vichinsky EP, Wang WC, Wethers DL, Younkin DP, Zimmerman …
• Correlation of abnormal intracranial vessel velocity, measured by transcranial Doppler ultrasonography, with abnormal conjunctival vessel velocity, measured by computer-assisted intravital microscopy, in sickle cell disease.
  Blood 2001 Cheung AT, Harmatz P, Wun T, Chen PC, Larkin EC, Adams RJ, Vichinsky EP
• Transfusion therapy: a coming-of-age treatment for patients with sickle cell disease.
  Journal of pediatric hematology/oncology 2001 Reed W, Vichinsky EP
• Nesidioblastosis in sickle cell disease.
  Pediatric pathology & molecular medicine 2001 Culberson DE, Manci EA, Shah AK, Haynes J, Ballas SK, Pegelow C, Vichinsky E
• Consensus document for transfusion-related iron overload.
  Seminars in hematology 2001 Vichinsky E
• Current issues with blood transfusions in sickle cell disease.
  Seminars in hematology 2001 Vichinsky EP
• Stable mixed hematopoietic chimerism after bone marrow transplantation for sickle cell anemia.
  Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2001 Walters MC, Patience M, Leisenring W, Rogers ZR, Aquino VM, Buchanan GR, Roberts IA, Yeager AM, Hsu L, Adamkiewicz T, Kurtzberg J, Vichinsky E, Storer B, Storb R, Sullivan KM, Multicenter …
• Stem cell transplantation for sickle cell disease: can we reduce the toxicity?
  Pediatric pathology & molecular medicine 2001 Fixler J, Vichinsky E, Walters MC
• Universal newborn screening for Hb H disease in California.
  Genetic testing 2001 Lorey F, Cunningham G, Vichinsky EP, Lubin BH, Witkowska HE, Matsunaga A, Azimi M, Sherwin J, Eastman J, Farina F, Waye JS, Chui DH
• Alloimmunization and erythrocyte autoimmunization in transfusion-dependent thalassemia patients of predominantly asian descent.
  Blood 2000 Singer ST, Wu V, Mignacca R, Kuypers FA, Morel P, Vichinsky EP
• Arginine therapy: a novel strategy to induce nitric oxide production in sickle cell disease.
  British journal of haematology 2000 Morris CR, Kuypers FA, Larkin S, Sweeters N, Simon J, Vichinsky EP, Styles LA
• Changing outcome of homozygous alpha-thalassemia: cautious optimism.
  Journal of pediatric hematology/oncology 2000 Singer ST, Styles L, Bojanowski J, Quirolo K, Foote D, Vichinsky EP
• Outreach strategies for Southeast Asian communities: experience, practice, and suggestions for approaching Southeast Asian immigrant and refugee communities to provide thalassemia education and trait testing.
  Journal of pediatric hematology/oncology 2000 Choy J, Foote D, Bojanowski J, Yamashita R, Vichinsky E
• Patterns of arginine and nitric oxide in patients with sickle cell disease with vaso-occlusive crisis and acute chest syndrome.
  Journal of pediatric hematology/oncology 2000 Morris CR, Kuypers FA, Larkin S, Vichinsky EP, Styles LA
• Secretory phospholipase A(2) predicts impending acute chest syndrome in sickle cell disease.
  Blood 2000 Styles LA, Aarsman AJ, Vichinsky EP, Kuypers FA
• Multicenter comparison of magnetic resonance imaging and transcranial Doppler ultrasonography in the evaluation of the central nervous system in children with sickle cell disease.
  Journal of pediatric hematology/oncology 2000 Wang WC, Gallagher DM, Pegelow CH, Wright EC, Vichinsky EP, Abboud MR, Moser FG, Adams RJ
• Severity of iron overload in patients with sickle cell disease receiving chronic red blood cell transfusion therapy.
  Blood 2000 Harmatz P, Butensky E, Quirolo K, Williams R, Ferrell L, Moyer T, Golden D, Neumayr L, Vichinsky E
• Use of hydroxyurea in children ages 2 to 5 years with sickle cell disease.
  Journal of pediatric hematology/oncology 2000 Hoppe C, Vichinsky E, Quirolo K, van Warmerdam J, Allen K, Styles L
• Causes and outcomes of the acute chest syndrome in sickle cell disease. National Acute Chest Syndrome Study Group.
  The New England journal of medicine 2000 Vichinsky EP, Neumayr LD, Earles AN, Williams R, Lennette ET, Dean D, Nickerson B, Orringer E, McKie V, Bellevue R, Daeschner C, Manci EA
• Evidence for HLA-related susceptibility for stroke in children with sickle cell disease.
  Blood 2000 Styles LA, Hoppe C, Klitz W, Vichinsky E, Lubin B, Trachtenberg E
• Impact of bone marrow transplantation for symptomatic sickle cell disease: an interim report. Multicenter investigation of bone marrow transplantation for sickle cell disease.
  Blood 2000 Walters MC, Storb R, Patience M, Leisenring W, Taylor T, Sanders JE, Buchanan GE, Rogers ZR, Dinndorf P, Davies SC, Roberts IA, Dickerhoff R, Yeager AM, Hsu L, Kurtzberg J, Ohene-Frempong K, Bunin N, …
• Sickle-cell disease not identified by newborn screening because of prior transfusion.
  The Journal of pediatrics 2000 Reed W, Lane PA, Lorey F, Bojanowski J, Glass M, Louie RR, Lubin BH, Vichinsky EP
• Major changes in sickle cell disease.
  Advances in pediatrics 2000 Hagar RW, Vichinsky EP
• Hydroxyurea and sodium phenylbutyrate therapy in thalassemia intermedia.
  American journal of hematology 1999 Hoppe C, Vichinsky E, Lewis B, Foote D, Styles L
• The perioperative complication rate of orthopedic surgery in sickle cell disease: report of the National Sickle Cell Surgery Study Group.
  American journal of hematology 1999 Vichinsky EP, Neumayr LD, Haberkern C, Earles AN, Eckman J, Koshy M, Black DM
• Transfusion practice for patients with sickle cell disease.
  Current opinion in hematology 1999 Reed WF, Vichinsky EP
• Bone disease in beta-thalassaemia.
  Lancet (London, England) 1999 Singer ST, Vichinsky EP
• Safety of hydroxyurea in children with sickle cell anemia: results of the HUG-KIDS study, a phase I/II trial. Pediatric Hydroxyurea Group.
  Blood 1999 Kinney TR, Helms RW, O'Branski EE, Ohene-Frempong K, Wang W, Daeschner C, Vichinsky E, Redding-Lallinger R, Gee B, Platt OS, Ware RE
• Effects of red blood cell transfusion on resting energy expenditure in adolescents with sickle cell anemia.
  Journal of pediatric gastroenterology and nutrition 1999 Harmatz P, Heyman MB, Cunningham J, Lee PD, Styles L, Quirolo K, Kopp-Hoolihan L, Ghiron J, Hintz RL, Vichinsky E
• Clinician assessment for acute chest syndrome in febrile patients with sickle cell disease: is it accurate enough?
  Annals of emergency medicine 1999 Morris C, Vichinsky E, Styles L
• Role of positron emission tomography in determining the extent of CNS ischemia in patients with sickle cell disease.
  American journal of hematology 1999 Reed W, Jagust W, Al-Mateen M, Vichinsky E
• Silent cerebral infarcts in sickle cell anemia: a risk factor analysis. The Cooperative Study of Sickle Cell Disease.
  Pediatrics 1999 Kinney TR, Sleeper LA, Wang WC, Zimmerman RA, Pegelow CH, Ohene-Frempong K, Wethers DL, Bello JA, Vichinsky EP, Moser FG, Gallagher DM, DeBaun MR, Platt OS, Miller ST
• Tonsillectomy, adenoidectomy, and myringotomy in sickle cell disease: perioperative morbidity. Preoperative Transfusion in Sickle Cell Disease Study Group.
  Journal of pediatric hematology/oncology 1999 Waldron P, Pegelow C, Neumayr L, Haberkern C, Earles A, Wesman R, Vichinsky E
• Deferoxamine treatment during pregnancy: is it harmful?
  American journal of hematology 1999 Singer ST, Vichinsky EP
• Erythrocytapheresis for chronically transfused children with sickle cell disease: an effective method for maintaining a low hemoglobin S level and reducing iron overload.
  Journal of clinical apheresis 1999 Singer ST, Quirolo K, Nishi K, Hackney-Stephens E, Evans C, Vichinsky EP
• Sample suitability for the detection of minor white cell populations (microchimerism) by polymerase chain reaction.
  Transfusion 1998 Reed W, Lee TH, Vichinsky EP, Lubin BH, Busch MP
• Prevention of a first stroke by transfusions in children with sickle cell anemia and abnormal results on transcranial Doppler ultrasonography.
  The New England journal of medicine 1998 Adams RJ, McKie VC, Hsu L, Files B, Vichinsky E, Pegelow C, Abboud M, Gallagher D, Kutlar A, Nichols FT, Bonds DR, Brambilla D
• Approaches to working with adult thalassemia patients in pediatric settings.
  Annals of the New York Academy of Sciences 1998 Weissman L, Treadwell M, Foote D, Heer N, Vichinsky EP
• Bone marrow transplant in thalassemia. A role for radiation?
  Annals of the New York Academy of Sciences 1998 Lee YS, Kristovich KM, Ducore JM, Vichinsky E, Crouse VL, Glader BE, Amylon MD
• Outreach strategies for Asian Pacific Island (API) communities.
  Annals of the New York Academy of Sciences 1998 Choy J, Yamashita RC, Foote D, Heer N, Vichinsky EP
• Preliminary report: hydroxyurea produces significant clinical response in thalassemia intermedia.
  Annals of the New York Academy of Sciences 1998 Styles L, Lewis B, Foote D, Cuda L, Vichinsky EP
• The hemoglobin E syndromes.
  Annals of the New York Academy of Sciences 1998 Rees DC, Styles L, Vichinsky EP, Clegg JB, Weatherall DJ
• The morbidity of bone disease in thalassemia.
  Annals of the New York Academy of Sciences 1998 Vichinsky EP
• The social impact of migration on disease. Cooley's anemia, thalassemia, and new Asian immigrants.
  Annals of the New York Academy of Sciences 1998 Heer N, Choy J, Vichinsky EP
• Correction of the anemia of epidermolysis bullosa with intravenous iron and erythropoietin.
  The Journal of pediatrics 1998 Fridge JL, Vichinsky EP
• Acute chest syndrome and sickle cell disease.
  Current opinion in hematology 1998 Golden C, Styles L, Vichinsky E
• Stroke prevention trial in sickle cell anemia.
  Controlled clinical trials 1998 Adams RJ, McKie VC, Brambilla D, Carl E, Gallagher D, Nichols FT, Roach S, Abboud M, Berman B, Driscoll C, Files B, Hsu L, Hurlet A, Miller S, Olivieri N, Pegelow C, Scher C, Vichinsky E, Wang W, …
• Surgery in patients with hemoglobin SC disease. Preoperative Transfusion in Sickle Cell Disease Study Group.
  American journal of hematology 1998 Neumayr L, Koshy M, Haberkern C, Earles AN, Bellevue R, Hassell K, Miller S, Black D, Vichinsky E
• The natural history of sickle cell disease.
  Current opinion in pediatrics 1998 Hoppe C, Styles L, Vichinsky E
• Hydroxyurea in children with sickle cell disease: impact on splenic function and compliance with therapy.
  Journal of pediatric hematology/oncology 1998 Olivieri NF, Vichinsky EP
• New considerations in the treatment of sickle cell disease.
  Annual review of medicine 1998 Reed W, Vichinsky EP
• Hydroxyurea in children: present and future.
  Seminars in hematology 1997 Vichinsky EP
• Influence of penicillin prophylaxis on antimicrobial resistance in nasopharyngeal S. pneumoniae among children with sickle cell anemia. The Ancillary Nasopharyngeal Culture Study of Prophylactic Penicillin Study II.
  Journal of pediatric hematology/oncology 1997 Woods GM, Jorgensen JH, Waclawiw MA, Reid C, Wang W, Pegelow CH, Rogers ZR, Iyer RV, Holbrook CT, Kinney TR, Vichinsky E, DeBaun MR, Grossman NJ, Thomas MD, Falletta JM
• Umbilical cord blood stem cells: application for the treatment of patients with hemoglobinopathies.
  The Journal of pediatrics 1997 Kelly P, Kurtzberg J, Vichinsky E, Lubin B
• Decrease of very late activation antigen-4 and CD36 on reticulocytes in sickle cell patients treated with hydroxyurea.
  Blood 1997 Styles LA, Lubin B, Vichinsky E, Lawrence S, Hua M, Test S, Kuypers F
• Acute chest syndrome in sickle cell disease: clinical presentation and course. Cooperative Study of Sickle Cell Disease.
  Blood 1997 Vichinsky EP, Styles LA, Colangelo LH, Wright EC, Castro O, Nickerson B
• Cholecystectomy in sickle cell anemia patients: perioperative outcome of 364 cases from the National Preoperative Transfusion Study. Preoperative Transfusion in Sickle Cell Disease Study Group.
  Blood 1997 Haberkern CM, Neumayr LD, Orringer EP, Earles AN, Robertson SM, Black D, Abboud MR, Koshy M, Idowu O, Vichinsky EP
• Natural history of blood pressure in sickle cell disease: risks for stroke and death associated with relative hypertension in sickle cell anemia.
  The American journal of medicine 1997 Pegelow CH, Colangelo L, Steinberg M, Wright EC, Smith J, Phillips G, Vichinsky E
• New therapies and approaches to transfusion in sickle cell disease in children.
  Current opinion in pediatrics 1997 Styles LA, Vichinsky EP
• Pulmonary complications.
  Hematology/oncology clinics of North America 1996 Vichinsky E, Styles L
• Serotype-specific immunoglobulin G antibody responses to pneumococcal polysaccharide vaccine in children with sickle cell anemia: effects of continued penicillin prophylaxis.
  The Journal of pediatrics 1996 Bjornson AB, Falletta JM, Verter JI, Buchanan GR, Miller ST, Pegelow CH, Iyer RV, Johnstone HS, DeBaun MR, Wethers DL, Wang WC, Woods GM, Holbrook CT, Becton DL, Kinney TR, Reaman GH, Kalinyak K, …
• First report of reversal of organ dysfunction in sickle cell anemia by the use of hydroxyurea: splenic regeneration.
  Blood 1996 Claster S, Vichinsky E
• Core decompression in avascular necrosis of the hip in sickle-cell disease.
  American journal of hematology 1996 Styles LA, Vichinsky EP
• Barriers to bone marrow transplantation for sickle cell anemia.
  Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 1996 Walters MC, Patience M, Leisenring W, Eckman JR, Buchanan GR, Rogers ZR, Olivieri NE, Vichinsky E, Davies SC, Mentzer WC, Powars D, Scott JP, Bernaudin F, Ohene-Frempong K, Darbyshire PJ, Wayne A, …
• The spectrum of brain MR abnormalities in sickle-cell disease: a report from the Cooperative Study of Sickle Cell Disease.
  AJNR. American journal of neuroradiology 1996 Moser FG, Miller ST, Bello JA, Pegelow CH, Zimmerman RA, Wang WC, Ohene-Frempong K, Schwartz A, Vichinsky EP, Gallagher D, Kinney TR
• Phospholipase A2 levels in acute chest syndrome of sickle cell disease.
  Blood 1996 Styles LA, Schalkwijk CG, Aarsman AJ, Vichinsky EP, Lubin BH, Kuypers FA
• Newborn screening for sickle cell disease: 4 years of experience from California's newborn screening program.
  Journal of pediatric hematology/oncology 1996 Shafer FE, Lorey F, Cunningham GC, Klumpp C, Vichinsky E, Lubin B
• Ototoxicity in hemoglobinopathy patients chelated with desferrioxamine.
  Journal of pediatric hematology/oncology 1996 Styles LA, Vichinsky EP
• Surgery and anesthesia in sickle cell disease. Cooperative Study of Sickle Cell Diseases.
  Blood 1995 Koshy M, Weiner SJ, Miller ST, Sleeper LA, Vichinsky E, Brown AK, Khakoo Y, Kinney TR
• Discontinuing penicillin prophylaxis in children with sickle cell anemia. Prophylactic Penicillin Study II.
  The Journal of pediatrics 1995 Falletta JM, Woods GM, Verter JI, Buchanan GR, Pegelow CH, Iyer RV, Miller ST, Holbrook CT, Kinney TR, Vichinsky E
• A comparison of conservative and aggressive transfusion regimens in the perioperative management of sickle cell disease. The Preoperative Transfusion in Sickle Cell Disease Study Group.
  The New England journal of medicine 1995 Vichinsky EP, Haberkern CM, Neumayr L, Earles AN, Black D, Koshy M, Pegelow C, Abboud M, Ohene-Frempong K, Iyer RV
• Clinical events in the first decade in a cohort of infants with sickle cell disease. Cooperative Study of Sickle Cell Disease.
  Blood 1995 Gill FM, Sleeper LA, Weiner SJ, Brown AK, Bellevue R, Grover R, Pegelow CH, Vichinsky E
• Risk of recurrent stroke in patients with sickle cell disease treated with erythrocyte transfusions.
  The Journal of pediatrics 1995 Pegelow CH, Adams RJ, McKie V, Abboud M, Berman B, Miller ST, Olivieri N, Vichinsky E, Wang W, Brambilla D
• Liver transplantation in a child with sickle cell anemia.
  Transplantation 1995 Lang T, Berquist WE, So SK, Cox KL, Rich EJ, Vichinsky E, Concepcion W, Esquivel CO
• Chronic pulmonary disorders in sickle cell disease: findings at thin-section CT.
  Radiology 1994 Aquino SL, Gamsu G, Fahy JV, Claster S, Embury SH, Mentzer WC, Vichinsky EP
• Effects of a long-term transfusion regimen on sickle cell-related illnesses.
  The Journal of pediatrics 1994 Styles LA, Vichinsky E
• Pulmonary fat embolism: a distinct cause of severe acute chest syndrome in sickle cell anemia.
  Blood 1994 Vichinsky E, Williams R, Das M, Earles AN, Lewis N, Adler A, McQuitty J
• New advances in the pathophysiology and management of sickle cell disease.
  Current opinion in hematology 1994 Shafer FE, Vichinsky E
• A cautionary note regarding hydroxyurea in sickle cell disease.
  Blood 1994 Vichinsky EP, Lubin BH
• Availability of related donors for bone marrow transplantation in sickle cell anemia.
  The American journal of pediatric hematology/oncology 1994 Mentzer WC, Heller S, Pearle PR, Hackney E, Vichinsky E
• Butyrate derivatives. New agents for stimulating fetal globin production in the beta-globin disorders.
  The American journal of pediatric hematology/oncology 1994 Perrine SP, Olivieri NF, Faller DV, Vichinsky EP, Dover GJ, Ginder GD
• Universal screening for hemoglobinopathies using high-performance liquid chromatography: clinical results of 2.2 million screens.
  European journal of human genetics : EJHG 1994 Lorey F, Cunningham G, Shafer F, Lubin B, Vichinsky E
• Detection of Hb E/beta-thalassemia versus homozygous EE using high-performance liquid chromatography results from newborns.
  Biochemical medicine and metabolic biology 1993 Lorey FW, Cunningham GC, Vichinsky E, Lubin B, Shafer F, Eastman J
• A short-term trial of butyrate to stimulate fetal-globin-gene expression in the beta-globin disorders.
  The New England journal of medicine 1993 Perrine SP, Ginder GD, Faller DV, Dover GH, Ikuta T, Witkowska HE, Cai SP, Vichinsky EP, Olivieri NF
• F reticulocyte response in sickle cell anemia treated with recombinant human erythropoietin: a double-blind study.
  Blood 1993 Nagel RL, Vichinsky E, Shah M, Johnson R, Spadacino E, Fabry ME, Mangahas L, Abel R, Stamatoyannopoulos G
• Differentiation of homozygous hemoglobin E from compound heterozygous hemoglobin E-beta O-thalassemia by hemoglobin E mutation analysis.
  The Journal of pediatrics 1992 Johnson JP, Vichinsky E, Hurst D, Camber A, Lubin B, Louie E
• Sickle cell disease in a patient with sickle cell trait and compound heterozygosity for hemoglobin S and hemoglobin Quebec-Chori.
  The New England journal of medicine 1991 Witkowska HE, Lubin BH, Beuzard Y, Baruchel S, Esseltine DW, Vichinsky EP, Kleman KM, Bardakdjian-Michau J, Pinkoski L, Cahn S
• Pain in sickle cell disease. Rates and risk factors.
  The New England journal of medicine 1991 Platt OS, Thorington BD, Brambilla DJ, Milner PF, Rosse WF, Vichinsky E, Kinney TR
• Comprehensive care in sickle cell disease: its impact on morbidity and mortality.
  Seminars in hematology 1991 Vichinsky EP
• Alloimmunization in sickle cell anemia and transfusion of racially unmatched blood.
  The New England journal of medicine 1990 Vichinsky EP, Earles A, Johnson RA, Hoag MS, Williams A, Lubin B
• Vitamin C deficiency in patients with sickle cell anemia.
  The American journal of pediatric hematology/oncology 1990 Chiu D, Vichinsky E, Ho SL, Liu T, Lubin BH
• Sodium butyrate enhances fetal globin gene expression in erythroid progenitors of patients with Hb SS and beta thalassemia.
  Blood 1989 Perrine SP, Miller BA, Faller DV, Cohen RA, Vichinsky EP, Hurst D, Lubin BH, Papayannopoulou T
• Experience with newborn screening using isoelectric focusing.
  Pediatrics 1989 Kleman KM, Vichinsky E, Lubin BH
• Elevated fasting breath hydrogen and abnormal hydrogen breath tests in children with sickle cell disease: a preliminary report.
  The American journal of clinical nutrition 1989 Heyman MB, Lande W, Vichinsky E, Mentzer W
• Butyrate analogues modulate globin gene expression in human and ovine erythroid cells.
  Progress in clinical and biological research 1989 Perrine SP, Miller BA, Papayannopoulou T, Faller DV, Rudolph AM, Vichinsky E, Hurst D, Kan YW
• Hematopoietic hormones: from cloning to clinic.
  The American journal of pediatric hematology/oncology 1989 Perrine SP, Vichinsky E, Faller DV
• Newborn screening for sickle cell disease: effect on mortality.
  Pediatrics 1988 Vichinsky E, Hurst D, Earles A, Kleman K, Lubin B
• Contraceptive use in the chronically ill adolescent female.
  Journal of adolescent health care : official publication of the Society for Adolescent Medicine 1988 Vichinsky E, McDonald C
• Suggested guidelines for the treatment of children with sickle cell anemia.
  Hematology/oncology clinics of North America 1987 Vichinsky E, Lubin BH
• Prophylaxis with oral penicillin in children with sickle cell anemia. A randomized trial.
  The New England journal of medicine 1986 Gaston MH, Verter JI, Woods G, Pegelow C, Kelleher J, Presbury G, Zarkowsky H, Vichinsky E, Iyer R, Lobel JS
• Growth retardation in sickle-cell disease treated by nutritional support.
  Lancet (London, England) 1985 Heyman MB, Vichinsky E, Katz R, Gaffield B, Hurst D, Castillo R, Chiu D, Kleman K, Ammann AJ, Thaler MM
• Long-term follow-up and booster immunization with polyvalent pneumococcal polysaccharide in patients with sickle cell anemia.
  The Journal of pediatrics 1984 Weintrub PS, Schiffman G, Addiego JE, Matthay KK, Vichinsky E, Johnson R, Lubin B, Mentzer WC, Ammann AJ
• Inadequate erythroid response to hypoxia in cystic fibrosis.
  The Journal of pediatrics 1984 Vichinsky EP, Pennathur-Das R, Nickerson B, Minor M, Kleman K, Higashino S, Lubin B
• Evidence for the presence of CFU-E with increased in vitro sensitivity to erythropoietin in sickle cell anemia.
  Blood 1984 Pennathur-Das R, Alpen E, Vichinsky E, Garcia J, Lubin B
• Evidence for a heterogeneous response to erythropoietin in the CFUE pool of human bone marrow.
  Experimental hematology 1984 Pennathur-Das R, Alpen E, Vichinsky E, Lubin B
• Iron deficiency in health and disease.
  Advances in pediatrics 1983 Reeves JD, Vichinsky E, Addiego J, Lubin BH
• Concurrent sickle-cell anemia and alpha-thalassemia: effect on severity of anemia.
  The New England journal of medicine 1982 Embury SH, Dozy AM, Miller J, Davis JR, Kleman KM, Preisler H, Vichinsky E, Lande WN, Lubin BH, Kan YW, Mentzer WC
• Multidisciplinary approach to pain management in sickle cell disease.
  The American journal of pediatric hematology/oncology 1982 Vichinsky EP, Johnson R, Lubin BH
• Peroxidation, vitamin E, and sickle-cell anemia.
  Annals of the New York Academy of Sciences 1982 Chiu D, Vichinsky E, Yee M, Kleman K, Lubin B
• The diagnosis of iron deficiency anemia in sickle cell disease.
  Blood 1981 Vichinsky E, Kleman K, Embury S, Lubin B
• Current treatment of sickle cell disease.
  Current problems in pediatrics 1980 Davis JR, Vichinsky EP, Lubin BH
• Sickle cell anemia and related hemoglobinopathies.
  Pediatric clinics of North America 1980 Vichinsky EP, Lubin BH
• Unstable hemoglobins, hemoglobins with altered oxygen affinity, and m-hemoglobins.
  Pediatric clinics of North America 1980 Vichinsky EP, Lubin BH
• Fetal Hb production during acute erythroid expansion. I. Observations in patients with transient erythroblastopenia and post-phlebotomy.
  British journal of haematology 1980 Papayannopoulou T, Vichinsky E, Stamatoyannopoulos G
• Anemia in the newborn period.
  Pediatric annals 1979 Lubin B, Vichinsky E
• Anemia associated with rheumatoid arthritis.
  The Journal of pediatrics 1979 Vichinsky EP
• Immune response after splenectomy.
  Lancet (London, England) 1978 Sullivan JL, Ochs HD, Schiffman G, Hammerschlag MR, Miser J, Vichinsky E, Wedgwood RJ
• Preparation and properties of a cell-free system from rat skin that catalyzes sterol biosynthesis.
  Journal of lipid research 1966 Gaylor JL, Delwiche CV, Brady DR, Green AJ
• Guidelines for the Management of Non Tranfusion Dependent Thalassemia (NTDT). Thalassemia International Federation, 2013
  Guidelines for the Management of Non Tranfusion Dependent Thalassemia (NTDT). Thalassemia International Federation, 2013. Taher A, Vichinsky E, Musallam K, Cappellini MD, Viprakasit V.