Elizabeth St Lezin, MD
Professor Emeritus
Laboratory Medicine
School of Medicine

Awards

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• Lab Medicine Faculty Teaching, UCSF, 2020
• Lab Medicine Faculty Teaching, UCSF, 2016

Education & Training

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• Fellow Laboratory Medicine University of California, San Francisco 1993
• Residency Laboratory Medicine University of California, San Francisco 1990
• MD Medicine University of California, Los Angeles 1987
• BS Biology Stanford University 1981

Grants and Projects

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• Why Do Metabolic Risk Factors Cluster with Hypertension?, NIH, 2000-2005
• Genetics of Hypertension, NIH, 1998-2003

Publications (23)

Top publication keywords:
Blood PressureRats, Inbred BNChromosomesReninFatigueAnemiaRats, Inbred SHRGene Transfer TechniquesAngiotensinogenChromosome MappingAmbulatory CareHypertension, RenalHypertensionY ChromosomeErythrocyte Transfusion

• Early and sustained improvement in fatigue-related quality of life following red blood cell transfusion in outpatients.
  Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation 2020 Bruhn R, Karafin MS, Hilton JF, Kaidarova Z, Spencer BR, Qu L, Snyder EL, Olin R, Murphy EL, St Lezin E, NHLBI Recipient Epidemiology and Donor Evaluation Study (REDS)-III Program
• Association of donor age, body mass index, hemoglobin, and smoking status with in-hospital mortality and length of stay among red blood cell-transfused recipients.
  Transfusion 2019 Roubinian NH, Westlake M, St Lezin EM, Edgren G, Brambilla DJ, Lee C, Bruhn R, Cable RG, Triulzi DJ, Glynn SA, Kleinman S, Murphy EL, NHLBI Recipient Epidemiology and Donor Evaluation Study-III (REDS-…
• The impact of recipient factors on the lower-than-expected hemoglobin increment in transfused outpatients with hematologic diseases.
  Transfusion 2019 Karafin MS, Bruhn R, Roubinian NH, Chowdhury D, Qu L, Snyder EL, Murphy EL, Brambilla D, Cable RG, Hilton JF, St Lezin E, NHLBI Recipient Epidemiology and Donor Evaluation (REDS)-III Study
• Association of Blood Donor Sex and Prior Pregnancy With Mortality Among Red Blood Cell Transfusion Recipients.
  JAMA 2019 Edgren G, Murphy EL, Brambilla DJ, Westlake M, Rostgaard K, Lee C, Cable RG, Triulzi D, Bruhn R, St Lezin EM, Erikstrup C, Ullum H, Glynn SA, Kleinman S, Hjalgrim H, Roubinian NH, NHLBI Recipient …
• Therapeutic impact of red blood cell transfusion on anemic outpatients: the RETRO study.
  Transfusion 2019 St Lezin E, Karafin MS, Bruhn R, Chowdhury D, Qu L, Bialkowski W, Merenda S, D'Andrea P, McCalla AL, Anderson L, Keating SM, Stone M, Snyder EL, Brambilla D, Murphy EL, Norris PJ, Hilton JF, Spencer …

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• Genetic isolation of quantitative trait loci for blood pressure development and renal mass on chromosome 5 in the spontaneously hypertensive rat.
  Physiological research 2003 Pravenec M, Kren V, Krenová D, Zídek V, Simáková M, Musilová A, Vorlícek J, Lezin ES, Kurtz TW
• Transgenic expression of CD36 in the spontaneously hypertensive rat is associated with amelioration of metabolic disturbances but has no effect on hypertension.
  Physiological research 2003 Pravenec M, Landa V, Zídek V, Musilová A, Kazdová L, Qi N, Wang J, St Lezin E, Kurtz TW
• Genetic analysis of metabolic defects in the spontaneously hypertensive rat.
  Mammalian genome : official journal of the International Mammalian Genome Society 2002 Pravenec M, Zídek V, Musilová A, Simáková M, Kostka V, Mlejnek P, Kren V, Krenova D, Bílá V, Míková B, Jáchymová M, Horký K, Kazdová L, St Lezin E, Kurtz TW
• Genetic isolation of a blood pressure quantitative trait locus on chromosome 2 in the spontaneously hypertensive rat.
  Journal of hypertension 2001 Pravenec M, Zídek V, Musilová A, Vorlícek J, Kren V, St Lezin E, Kurtz TW
• Y-chromosome transfer induces changes in blood pressure and blood lipids in SHR.
  Hypertension (Dallas, Tex. : 1979) 2001 Kren V, Qi N, Krenova D, Zidek V, Sladká M, Jáchymová M, Míková B, Horky K, Bonne A, Van Lith HA, Van Zutphen BF, Lau YF, Pravenec M, St Lezin E
• Hypoalgesia and hyperalgesia with inherited hypertension in the rat.
  American journal of physiology. Regulatory, integrative and comparative physiology 2001 Taylor BK, Roderick RE, St Lezin E, Basbaum AI
• Transgenic rescue of defective Cd36 ameliorates insulin resistance in spontaneously hypertensive rats.
  Nature genetics 2001 Pravenec M, Landa V, Zidek V, Musilova A, Kren V, Kazdova L, Aitman TJ, Glazier AM, Ibrahimi A, Abumrad NA, Qi N, Wang JM, St Lezin EM, Kurtz TW
• Genetic susceptibility to renal injury in hypertension.
  Experimental nephrology 2001 Bidani AK, Griffin KA, Churchill PC, Churchill MC, St Lezin E, Kurtz TW
• Genetic analysis of rat chromosome 1 and the Sa gene in spontaneous hypertension.
  Hypertension (Dallas, Tex. : 1979) 2000 St Lezin E, Liu W, Wang JM, Yang Y, Qi N, Kren V, Zidek V, Kurtz TW, Pravenec M
• Genetic isolation of a chromosome 1 region affecting susceptibility to hypertension-induced renal damage in the spontaneously hypertensive rat.
  Hypertension (Dallas, Tex. : 1979) 1999 St Lezin E, Griffin KA, Picken M, Churchill MC, Churchill PC, Kurtz TW, Liu W, Wang N, Kren V, Zidek V, Pravenec M, Bidani AK
• Congenic strains for genetic analysis of hypertension and dyslipidemia in the spontaneously hypertensive rat.
  Transplantation proceedings 1999 Pravenec M, Krenová D, Kren V, Zídek V, Simáková M, Musilová A, Bottger A, van Zutphen BF, St Lezin E, Kurtz TW
• Effect of chromosome 19 transfer on blood pressure in the spontaneously hypertensive rat.
  Hypertension (Dallas, Tex. : 1979) 1999 St Lezin E, Zhang L, Yang Y, Wang JM, Wang N, Qi N, Steadman JS, Liu W, Kren V, Zidek V, Krenova D, Churchill PC, Churchill MC, Pravenec M
• Identification of Cd36 (Fat) as an insulin-resistance gene causing defective fatty acid and glucose metabolism in hypertensive rats.
  Nature genetics 1999 Aitman TJ, Glazier AM, Wallace CA, Cooper LD, Norsworthy PJ, Wahid FN, Al-Majali KM, Trembling PM, Mann CJ, Shoulders CC, Graf D, St Lezin E, Kurtz TW, Kren V, Pravenec M, Ibrahimi A, Abumrad NA, …
• Effect of renin gene transfer on blood pressure in the spontaneously hypertensive rat.
  Hypertension (Dallas, Tex. : 1979) 1998 St Lezin E, Liu W, Wang N, Wang JM, Kren V, Zidek V, Zdobinska M, Krenova D, Bottger A, van Zutphen BF, Pravenec M
• Genetic isolation of a chromosome 1 region affecting blood pressure in the spontaneously hypertensive rat.
  Hypertension (Dallas, Tex. : 1979) 1997 St Lezin E, Liu W, Wang JM, Wang N, Kren V, Krenova D, Musilova A, Zdobinska M, Zidek V, Lau D, Pravenec M
• Genetic susceptibility to hypertension-induced renal damage in the rat. Evidence based on kidney-specific genome transfer.
  The Journal of clinical investigation 1997 Churchill PC, Churchill MC, Bidani AK, Griffin KA, Picken M, Pravenec M, Kren V, St Lezin E, Wang JM, Wang N, Kurtz TW
• Linkage mapping of the mixed-lineage leukemia (Mll) gene to rat chromosome 8.
  Mammalian genome : official journal of the International Mammalian Genome Society 1997 Pravenec M, Wang J, Kren V, St Lezin E
• Mapping genes controlling hematocrit in the spontaneously hypertensive rat.
  Mammalian genome : official journal of the International Mammalian Genome Society 1997 Pravenec M, Zidek V, Zdobinska M, Kren V, Krenova D, Bottger A, van Zutphen LF, Wang J, St Lezin E