Elizabeth Rose Mayeda, PhD
Professor
Epidemiology & Biostatistics
School of Medicine

Evidence on when inequalities relevant to dementia begin to emerge and the mechanisms that culminate in dementia, often decades later, will help identify effective strategies to reduce disparities. Social and structural inequalities likely play a key role, and increasing evidence implicates cardiovascular risk factors as more proximal mechanisms. To address these research questions rigorously, my work emphasizes methods to strengthen causal inference, especially tools to quantify and remediate selection bias. My long-term research goals are to: (1) identify effective strategies to prevent dementia and reduce racial and ethnic disparities in dementia and (2) develop research tools to strengthen causal inference in dementia research and lifecourse epidemiology.

• Joint Models for Estimating Determinants of Cognitive Decline in the Presence of Survival Bias.
  Epidemiology (Cambridge, Mass.) 2022 Davis-Plourde KL, Mayeda ER, Lodi S, Filshtein T, Beiser A, Gross AL, Seshadri S, Glymour MM, Tripodis Y
• Neighborhood disadvantage and dementia incidence in a cohort of Asian American and non-Latino White older adults in Northern California.
  Alzheimer's & dementia : the journal of the Alzheimer's Association 2022 Mobley TM, Shaw C, Hayes-Larson E, Fong J, Gilsanz P, Gee GC, Brookmeyer R, Whitmer RA, Casey JA, Mayeda ER
• Measuring Cognitive Health in Ethnically Diverse Older Adults.
  The journals of gerontology. Series B, Psychological sciences and social sciences 2022 Hernandez Saucedo H, Whitmer RA, Glymour M, DeCarli C, Mayeda ER, Gilsanz P, Miles SQ, Bhulani N, Tomaszewski Farias S, Olichney J, Mungas D
• Perceived Discrimination, Nativity, and Cognitive Performance in a Multiethnic Study of Older Adults: Findings From the Kaiser Healthy Aging and Diverse Life Experiences Study.
  The journals of gerontology. Series A, Biological sciences and medical sciences 2022 Meza E, Peterson R, Gilsanz P, George KM, Miles SJ, Eng CW, Mungas DM, Mayeda ER, Glymour MM, Whitmer RA
• Accounting for lack of representation in dementia research: Generalizing KHANDLE study findings on the prevalence of cognitive impairment to the California older population.
  Alzheimer's & dementia : the journal of the Alzheimer's Association 2022 Hayes-Larson E, Mobley TM, Mungas D, Seamans MJ, Glymour MM, Gilsanz P, DeCarli C, Whitmer RA, Mayeda ER
• The role of nativity in heterogeneous dementia incidence in a large cohort of three Asian American groups and white older adults in California.
  Alzheimer's & dementia : the journal of the Alzheimer's Association 2022 Hayes-Larson E, Fong J, Mobley TM, Gilsanz P, Whitmer RA, Gee GC, Brookmeyer R, Mayeda ER
• Association of Social Integration with Cognitive Status in a Multi-Ethnic Cohort: Results From the Kaiser Healthy Aging and Diverse Life Experiences Study.
  Journal of geriatric psychiatry and neurology 2022 Calmasini C, Swinnerton KN, Zimmerman SC, Peterson RL, George KM, Gilsanz P, Hayes-Larson E, Mayeda ER, Mungas DM, Whitmer RA, Glymour MM
• Monte Carlo Simulation Approaches for Quantitative Bias Analysis: A Tutorial.
  Epidemiologic reviews 2022 Banack HR, Hayes-Larson E, Mayeda ER
• Cognitive impairment in racially/ethnically diverse older adults: Accounting for sources of diagnostic bias.
  Alzheimer's & dementia (Amsterdam, Netherlands) 2021 Mungas D, Shaw C, Hayes-Larson E, DeCarli C, Farias ST, Olichney J, Saucedo HH, Gilsanz P, Glymour MM, Whitmer RA, Mayeda ER
• Association of Timing of School Desegregation in the United States With Late-Life Cognition in the Study of Healthy Aging in African Americans (STAR) Cohort.
  JAMA network open 2021 Peterson RL, George KM, Barnes LL, Gilsanz P, Mayeda ER, Glymour MM, Mungas DM, Whitmer RA
• Estimating the joint effect of diabetes and subsequent depressive symptoms on mortality among older latinos.
  Annals of epidemiology 2021 Inoue K, Mayeda ER, Nianogo R, Paul K, Yu Y, Haan M, Ritz B
• Stroke Belt birth state and late-life cognition in the Study of Healthy Aging in African Americans (STAR).
  Annals of epidemiology 2021 George KM, Peterson RL, Gilsanz P, Barnes LL, Mayeda ER, Glymour MM, Mungas DM, DeCarli CS, Whitmer RA
• Low HbA1c levels and all-cause or cardiovascular mortality among people without diabetes: the US National Health and Nutrition Examination Survey 1999-2015.
  International journal of epidemiology 2021 Inoue K, Nianogo R, Telesca D, Goto A, Khachadourian V, Tsugawa Y, Sugiyama T, Mayeda ER, Ritz B
• Impact of Cardiovascular Risk Factors in Adolescence, Young Adulthood, and Midlife on Late-Life Cognition: Study of Healthy Aging in African Americans.
  The journals of gerontology. Series A, Biological sciences and medical sciences 2021 George KM, Gilsanz P, Peterson RL, Barnes LL, DeCarli CS, Mayeda ER, Mungas DM, Whitmer RA
• The Association Between Cancer and Spousal Rate of Memory Decline: A Negative Control Study to Evaluate (Unmeasured) Social Confounding of the Cancer-memory Relationship.
  Alzheimer disease and associated disorders 2021 Ospina-Romero M, Brenowitz WD, Glymour MM, Mayeda ER, Graff RE, Witte JS, Ackley SF, Lu KP, Kobayashi LC
• Participant education, spousal education and dementia risk in a diverse cohort of members of an integrated health care delivery system in Northern California.
  BMJ open 2021 Gilsanz P, Mayeda ER, Eng CW, Meyer OL, Glymour MM, Quesenberry CP, Whitmer RA
• Lifecourse socioeconomic changes and late-life cognition in a cohort of U.S.-born and U.S. immigrants: findings from the KHANDLE study.
  BMC public health 2021 Peterson RL, George KM, Gilsanz P, Mayeda ER, Glymour MM, Meyer OL, Mungas DM, DeCarli C, Whitmer RA
• Do the Benefits of Educational Attainment for Late-life Cognition Differ by Racial/Ethnic Group?: Evidence for Heterogenous Treatment Effects in the Kaiser Healthy Aging and Diverse Life Experience (KHANDLE) Study.
  Alzheimer disease and associated disorders 2021 Eng CW, Glymour MM, Gilsanz P, Mungas DM, Mayeda ER, Meyer OL, Whitmer RA
• Racial/Ethnic Disparities in Young Adulthood and Midlife Cardiovascular Risk Factors and Late-life Cognitive Domains: The Kaiser Healthy Aging and Diverse Life Experiences (KHANDLE) Study.
  Alzheimer disease and associated disorders 2021 Peterson RL, George KM, Gilsanz P, Ackley S, Mayeda ER, Glymour MM, Mungas DM, DeCarli C, Whitmer RA
• Temporal Trends in Stroke-Related Memory Change: Results From a US National Cohort 1998-2016.
  Stroke 2021 Eng CW, Mayeda ER, Gilsanz P, Whitmer RA, Kim AS, Glymour MM
• Evaluation of Selective Survival and Sex/Gender Differences in Dementia Incidence Using a Simulation Model.
  JAMA network open 2021 Shaw C, Hayes-Larson E, Glymour MM, Dufouil C, Hohman TJ, Whitmer RA, Kobayashi LC, Brookmeyer R, Mayeda ER
• Effect of reductions in amyloid levels on cognitive change in randomized trials: instrumental variable meta-analysis.
  BMJ (Clinical research ed.) 2021 Ackley SF, Zimmerman SC, Brenowitz WD, Tchetgen Tchetgen EJ, Gold AL, Manly JJ, Mayeda ER, Filshtein TJ, Power MC, Elahi FM, Brickman AM, Glymour MM
• Are adverse childhood experiences associated with late-life cognitive performance across racial/ethnic groups: results from the Kaiser Healthy Aging and Diverse Life Experiences study baseline.
  BMJ open 2021 Gold AL, Meza E, Ackley SF, Mungas DM, Whitmer RA, Mayeda ER, Miles S, Eng CW, Gilsanz P, Glymour MM
• Comparison of Education and Episodic Memory as Modifiers of Brain Atrophy Effects on Cognitive Decline: Implications for Measuring Cognitive Reserve.
  Journal of the International Neuropsychological Society : JINS 2021 Mungas D, Fletcher E, Gavett BE, Widaman K, Zahodne LB, Hohman TJ, Mayeda ER, Dowling NM, Johnson DK, Tomaszewski Farias S
• Physical Performance and Cognition in a Diverse Cohort: Kaiser Healthy Aging and Diverse Life Experiences (KHANDLE) Study.
  Alzheimer disease and associated disorders 2021 George KM, Gilsanz P, Peterson RL, Glymour MM, Mayeda ER, Mungas DM, Miles SQ, Whitmer RA
• Generation and age of immigration on later life cognitive performance in KHANDLE.
  International psychogeriatrics 2020 Meyer OL, Eng CW, Ko MJ, Chan ML, Ngo U, Gilsanz P, Glymour MM, Mayeda ER, Mungas DM, Whitmer RA
• Metabolic dysfunction modifies the influence of traffic-related air pollution and noise exposure on late-life dementia and cognitive impairment: A cohort study of older Mexican-Americans.
  Environmental epidemiology (Philadelphia, Pa.) 2020 Yu Y, Haan M, Paul KC, Mayeda ER, Jerrett M, Wu J, Lee E, Su J, Shih IF, Inoue K, Ritz BR
• Racial/Ethnic Differences in Health-Related Quality of Life in Persons With and Without Dementia.
  Journal of the American Geriatrics Society 2020 Hayes-Larson E, Mobley TM, Gilmore-Bykovskyi A, Shaw C, Karlamangla A, Manly JJ, Mayeda ER
• Association of work-family experience with mid- and late-life memory decline in US women.
  Neurology 2020 Mayeda ER, Mobley TM, Weiss RE, Murchland AR, Berkman LF, Sabbath EL
• Association Between Alzheimer Disease and Cancer With Evaluation of Study Biases: A Systematic Review and Meta-analysis.
  JAMA network open 2020 Ospina-Romero M, Glymour MM, Hayes-Larson E, Mayeda ER, Graff RE, Brenowitz WD, Ackley SF, Witte JS, Kobayashi LC
• Traffic-related Noise Exposure and Late-life Dementia and Cognitive Impairment in Mexican-Americans.
  Epidemiology (Cambridge, Mass.) 2020 Yu Y, Mayeda ER, Paul KC, Lee E, Jerrett M, Su J, Wu J, Shih IF, Haan M, Ritz B
• Mediation of the Associations of Physical Activity With Cardiovascular Events and Mortality by Diabetes in Older Mexican Americans.
  American journal of epidemiology 2020 Inoue K, Mayeda ER, Paul KC, Shih IF, Yan Q, Yu Y, Haan M, Ritz BR
• The competing risk of death and selective survival cannot fully explain the inverse cancer-dementia association.
  Alzheimer's & dementia : the journal of the Alzheimer's Association 2020 Hayes-Larson E, Ackley SF, Zimmerman SC, Ospina-Romero M, Glymour MM, Graff RE, Witte JS, Kobayashi LC, Mayeda ER
• Racial/Ethnic Differences in Sleep Quality among Older Adults: Kaiser Healthy Aging and Diverse Life Experiences (KHANDLE) Study.
  Ethnicity & disease 2020 George KM, Peterson RL, Gilsanz P, Mungas DM, Glymour MM, Mayeda ER, Whitmer RA
• Association Between Cognitive Test Performance and Subjective Cognitive Decline in a Diverse Cohort of Older Adults: Findings From the KHANDLE Study.
  Alzheimer disease and associated disorders 2020 Corlier FW, Shaw C, Hayes-Larson E, Mungas D, Tomaszewski Farias S, Glymour MM, Whitmer RA, Mayeda ER
• Traffic-Related Air Pollution and Incident Dementia: Direct and Indirect Pathways Through Metabolic Dysfunction.
  Journal of Alzheimer's disease : JAD 2020 Paul KC, Haan M, Yu Y, Inoue K, Mayeda ER, Dang K, Wu J, Jerrett M, Ritz B
• Air pollution, noise exposure, and metabolic syndrome - A cohort study in elderly Mexican-Americans in Sacramento area.
  Environment international 2019 Yu Y, Paul K, Arah OA, Mayeda ER, Wu J, Lee E, Shih IF, Su J, Jerrett M, Haan M, Ritz B
• The role of education in a vascular pathway to episodic memory: brain maintenance or cognitive reserve?
  Neurobiology of aging 2019 Zahodne LB, Mayeda ER, Hohman TJ, Fletcher E, Racine AM, Gavett B, Manly JJ, Schupf N, Mayeux R, Brickman AM, Mungas D
• Inequalities in elevated depressive symptoms in middle-aged and older adults by rural childhood residence: The important role of education.
  International journal of geriatric psychiatry 2019 Murchland AR, Eng CW, Casey JA, Torres JM, Mayeda ER
• Invited Commentary: Examining Sex/Gender Differences in Risk of Alzheimer Disease and Related Dementias-Challenges and Future Directions.
  American journal of epidemiology 2019 Mayeda ER
• Reserve and Alzheimer's disease genetic risk: Effects on hospitalization and mortality.
  Alzheimer's & dementia : the journal of the Alzheimer's Association 2019 Filshtein TJ, Brenowitz WD, Mayeda ER, Hohman TJ, Walter S, Jones RN, Elahi FM, Glymour MM
• Stressors in Midlife and Risk of Dementia: The Role of Race and Education.
  Alzheimer disease and associated disorders 2019 Gilsanz P, Quesenberry CP, Mayeda ER, Glymour MM, Farias ST, Whitmer RA
• Rate of Memory Change Before and After Cancer Diagnosis.
  JAMA network open 2019 Ospina-Romero M, Abdiwahab E, Kobayashi L, Filshtein T, Brenowitz WD, Mayeda ER, Glymour MM
• Ambient Air Pollution, Noise, and Late-Life Cognitive Decline and Dementia Risk.
  Annual review of public health 2019 Paul KC, Haan M, Mayeda ER, Ritz BR
• Incidence of dementia after age 90 in a multiracial cohort.
  Alzheimer's & dementia : the journal of the Alzheimer's Association 2019 Gilsanz P, Corrada MM, Kawas CH, Mayeda ER, Glymour MM, Quesenberry CP, Lee C, Whitmer RA
• Associations of Income Volatility With Incident Cardiovascular Disease and All-Cause Mortality in a US Cohort.
  Circulation 2019 Elfassy T, Swift SL, Glymour MM, Calonico S, Jacobs DR, Mayeda ER, Kershaw KN, Kiefe C, Zeki Al Hazzouri A
• Sex Differences in the Genetic Architecture of Alzheimer's Disease.
  Current genetic medicine reports 2019 Dumitrescu L, Mayeda ER, Sharman K, Moore AM, Hohman TJ
• Birth in High Infant Mortality States and Dementia Risk in a Cohort of Elderly African American and White Health Care Members.
  Alzheimer disease and associated disorders 2019 Gilsanz P, Mayeda ER, Glymour MM, Quesenberry CP, Mungas D, DeCarli CS, Whitmer RA
• Does selective survival before study enrolment attenuate estimated effects of education on rate of cognitive decline in older adults? A simulation approach for quantifying survival bias in life course epidemiology.
  International journal of epidemiology 2018 Mayeda ER, Filshtein TJ, Tripodis Y, Glymour MM, Gross AL
• Early Midlife Pulmonary Function and Dementia Risk.
  Alzheimer disease and associated disorders 2018 Gilsanz P, Mayeda ER, Flatt J, Glymour MM, Quesenberry CP, Whitmer RA
• Progress and future challenges in aging and diversity research in the United States.
  Alzheimer's & dementia : the journal of the Alzheimer's Association 2018 Brewster P, Barnes L, Haan M, Johnson JK, Manly JJ, Nápoles AM, Whitmer RA, Carvajal-Carmona L, Early D, Farias S, Mayeda ER, Melrose R, Meyer OL, Zeki Al Hazzouri A, Hinton L, Mungas D
• Mother's education and late-life disparities in memory and dementia risk among US military veterans and non-veterans.
  Journal of epidemiology and community health 2018 Vable AM, Eng CW, Mayeda ER, Basu S, Marden JR, Hamad R, Glymour MM
• Will biomarker-based diagnosis of Alzheimer's disease maximize scientific progress? Evaluating proposed diagnostic criteria.
  European journal of epidemiology 2018 Glymour MM, Brickman AM, Kivimaki M, Mayeda ER, Chêne G, Dufouil C, Manly JJ
• Measures of SES for Electronic Health Record-based Research.
  American journal of preventive medicine 2017 Casey JA, Pollak J, Glymour MM, Mayeda ER, Hirsch AG, Schwartz BS
• Female sex, early-onset hypertension, and risk of dementia.
  Neurology 2017 Gilsanz P, Mayeda ER, Glymour MM, Quesenberry CP, Mungas DM, DeCarli C, Dean A, Whitmer RA
• Association Between Birth in a High Stroke Mortality State, Race, and Risk of Dementia.
  JAMA neurology 2017 Gilsanz P, Mayeda ER, Glymour MM, Quesenberry CP, Whitmer RA
• Heterogeneity in 14-year Dementia Incidence Between Asian American Subgroups.
  Alzheimer disease and associated disorders 2017 Mayeda ER, Glymour MM, Quesenberry CP, Whitmer RA
• Compartmental Model Diagrams as Causal Representations in Relation to DAGs.
  Epidemiologic methods 2017 Ackley SF, Mayeda ER, Worden L, Enanoria WTA, Glymour MM, Porco TC
• Perceived Walking Speed, Measured Tandem Walk, Incident Stroke, and Mortality in Older Latino Adults: A Prospective Cohort Study.
  The journals of gerontology. Series A, Biological sciences and medical sciences 2017 Zeki Al Hazzouri A, Mayeda ER, Elfassy T, Lee A, Odden MC, Thekkethala D, Wright CB, Glymour MM, Haan MN
• Physical activity, but not body mass index, predicts less disability before and after stroke.
  Neurology 2017 Rist PM, Capistrant BD, Mayeda ER, Liu SY, Glymour MM
• Survival after dementia diagnosis in five racial/ethnic groups.
  Alzheimer's & dementia : the journal of the Alzheimer's Association 2017 Mayeda ER, Glymour MM, Quesenberry CP, Johnson JK, Pérez-Stable EJ, Whitmer RA
• High Hemoglobin A1c and Diabetes Predict Memory Decline in the Health and Retirement Study.
  Alzheimer disease and associated disorders 2017 Marden JR, Mayeda ER, Tchetgen Tchetgen EJ, Kawachi I, Glymour MM
• The Obesity Paradox in Survival after Cancer Diagnosis: Tools for Evaluation of Potential Bias.
  Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2017 Mayeda ER, Glymour MM
• Commentary: Selection Bias in Clinical Epidemiology: Causal Thinking to Guide Patient-centered Research.
  Epidemiology (Cambridge, Mass.) 2016 Glymour MM, Mayeda ER, Selby VN
• Using an Alzheimer Disease Polygenic Risk Score to Predict Memory Decline in Black and White Americans Over 14 Years of Follow-up.
  Alzheimer disease and associated disorders 2016 Marden JR, Mayeda ER, Walter S, Vivot A, Tchetgen Tchetgen EJ, Kawachi I, Glymour MM
• Jump, Hop, or Skip: Modeling Practice Effects in Studies of Determinants of Cognitive Change in Older Adults.
  American journal of epidemiology 2016 Vivot A, Power MC, Glymour MM, Mayeda ER, Benitez A, Spiro A, Manly JJ, Proust-Lima C, Dufouil C, Gross AL
• Diabetic Phenotypes and Late-Life Dementia Risk: A Mechanism-specific Mendelian Randomization Study.
  Alzheimer disease and associated disorders 2016 Walter S, Marden JR, Kubzansky LD, Mayeda ER, Crane PK, Chang SC, Cornelis M, Rehkopf DH, Mukherjee S, Glymour MM
• Does type 2 diabetes increase rate of cognitive decline in older Mexican Americans?
  Alzheimer disease and associated disorders 2015 Mayeda ER, Haan MN, Yaffe K, Kanaya AM, Neuhaus J
• Body mass index and cognitive function: the potential for reverse causation.
  International journal of obesity (2005) 2015 Suemoto CK, Gilsanz P, Mayeda ER, Glymour MM
• Diabetes and cognition.
  Clinics in geriatric medicine 2014 Mayeda ER, Whitmer RA, Yaffe K
• Type 2 diabetes and cognitive decline over 14 years in middle-aged African Americans and whites: the ARIC Brain MRI Study.
  Neuroepidemiology 2014 Mayeda ER, Haan MN, Neuhaus J, Yaffe K, Knopman DS, Sharrett AR, Griswold ME, Mosley TH
• Racial/ethnic differences in dementia risk among older type 2 diabetic patients: the diabetes and aging study.
  Diabetes care 2013 Mayeda ER, Karter AJ, Huang ES, Moffet HH, Haan MN, Whitmer RA
• Weight and body composition changes during oral contraceptive use in obese and normal weight women.
  Journal of women's health (2002) 2013 Mayeda ER, Torgal AH, Westhoff CL
• Type 2 diabetes and 10-year risk of dementia and cognitive impairment among older Mexican Americans.
  Diabetes care 2013 Mayeda ER, Haan MN, Kanaya AM, Yaffe K, Neuhaus J
• Immigrant generation and diabetes risk among Mexican Americans: the Sacramento Area Latino Study on Aging.
  American journal of public health 2013 Afable-Munsuz A, Mayeda ER, Pérez-Stable EJ, Haan MN
• Pharmacokinetics and ovarian suppression during use of a contraceptive vaginal ring in normal-weight and obese women.
  American journal of obstetrics and gynecology 2012 Westhoff CL, Torgal AH, Mayeda ER, Petrie K, Thomas T, Dragoman M, Cremers S
• The association of blood pressure and mortality differs by self-reported walking speed in older Latinos.
  The journals of gerontology. Series A, Biological sciences and medical sciences 2012 Odden MC, Covinsky KE, Neuhaus JM, Mayeda ER, Peralta CA, Haan MN
• Helicobacter pylori infection is associated with an increased rate of diabetes.
  Diabetes care 2012 Jeon CY, Haan MN, Cheng C, Clayton ER, Mayeda ER, Miller JW, Aiello AE
• Predictors of noncompliance in an oral contraceptive clinical trial.
  Contraception 2011 Westhoff CL, Torgal AT, Mayeda ER, Shimoni N, Stanczyk FZ, Pike MC
• Ovarian suppression in normal-weight and obese women during oral contraceptive use: a randomized controlled trial.
  Obstetrics and gynecology 2010 Westhoff CL, Torgal AH, Mayeda ER, Stanczyk FZ, Lerner JP, Benn EKT, Paik M
• Apolipoprotein E Genotype and Cardiovascular Diseases in the Elderly.
  Current cardiovascular risk reports 2010 Haan MN, Mayeda ER
• Pharmacokinetics of a combined oral contraceptive in obese and normal-weight women.
  Contraception 2010 Westhoff CL, Torgal AH, Mayeda ER, Pike MC, Stanczyk FZ