Elena Montauti, PhD
Postdoctoral Scholar
Medicine
School of Medicine

Publications (9)

Top publication keywords:
MethyltransferasesEndoplasmic Reticulum StressLeukemia, Myelomonocytic, JuvenileEndoplasmic ReticulumT-Lymphocytes, RegulatoryTumor MicroenvironmentForkhead Transcription FactorsTransforming Growth Factor betaUbiquitin-Protein LigasesAdenineUbiquitinEndoplasmic Reticulum-Associated DegradationAutoimmunityLeukemia, MyeloidEndopeptidases

• Mediator complex subunit 1 architects a tumorigenic Treg cell program independent of inflammation.
  Cell reports. Medicine 2024 Chaudhuri SM, Weinberg SE, Wang D, Yalom LK, Montauti E, Iyer R, Tang AY, Torres Acosta MA, Shen J, Mani NL, Wang S, Liu K, Lu W, Bui TM, Manzanares LD, Dehghani Z, Wai CM, Gao B, Wei J, Yue F, Cui W,…
• Lymphocyte activation gene 3 (Lag3) supports Foxp3 + Treg cell function by restraining c-Myc-dependent aerobic glycolysis.
  bioRxiv : the preprint server for biology 2023 Kim D, Kim G, Yu R, Lee J, Kim S, Qiu K, Montauti E, Fang D, Chandel NS, Choi J, Min B
• A deubiquitination module essential for Treg fitness in the tumor microenvironment.
  Science advances 2022 Montauti E, Weinberg SE, Chu P, Chaudhuri S, Mani NL, Iyer R, Zhou Y, Zhang Y, Liu C, Xin C, Gregory S, Wei J, Zhang Y, Chen W, Sun Z, Yan M, Fang D
• HRD1-mediated METTL14 degradation regulates m6A mRNA modification to suppress ER proteotoxic liver disease.
  Molecular cell 2021 Wei J, Harada BT, Lu D, Ma R, Gao B, Xu Y, Montauti E, Mani N, Chaudhuri SM, Gregory S, Weinberg SE, Zhang DD, Green R, He C, Fang D
• Regulation of Treg Functions by the Ubiquitin Pathway.
  Advances in experimental medicine and biology 2021 Montauti E, Fang D

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• CRISPR screen in regulatory T cells reveals modulators of Foxp3.
  Nature 2020 Cortez JT, Montauti E, Shifrut E, Gatchalian J, Zhang Y, Shaked O, Xu Y, Roth TL, Simeonov DR, Zhang Y, Chen S, Li Z, Woo JM, Ho J, Vogel IA, Prator GY, Zhang B, Lee Y, Sun Z, Ifergan I, Van Gool F, …
• The E3 ligase Hrd1 stabilizes Tregs by antagonizing inflammatory cytokine-induced ER stress response.
  JCI insight 2019 Xu Y, Melo-Cardenas J, Zhang Y, Gau I, Wei J, Montauti E, Zhang Y, Gao B, Jin H, Sun Z, Lee SM, Fang D
• USP22 deficiency leads to myeloid leukemia upon oncogenic Kras activation through a PU.1-dependent mechanism.
  Blood 2018 Melo-Cardenas J, Xu Y, Wei J, Tan C, Kong S, Gao B, Montauti E, Kirsammer G, Licht JD, Yu J, Ji P, Crispino JD, Fang D
• Kin cell lysis is a danger signal that activates antibacterial pathways of Pseudomonas aeruginosa.
  eLife 2015 LeRoux M, Kirkpatrick RL, Montauti EI, Tran BQ, Peterson SB, Harding BN, Whitney JC, Russell AB, Traxler B, Goo YA, Goodlett DR, Wiggins PA, Mougous JD