Effie Ioannidou, DDS, MDS
Professor
Orofacial Sciences
School of Dentistry
Dr. Effie Ioannidou is a clinician scientist with training in Periodontology. Her research addresses clinical and translational questions on the anti-inflammatory effect of periodontal interventions in systemic health and chronic kidney disease. She has recently led a multicenter team of investigators to explore systemic antibiotic prescribing patterns in combination with periodontal therapy.
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By leveraging advanced molecular techniques, her team aims to advance the field and provide evidence-based guidance for clinicians, ultimately leading to more effective and sustainable periodontal treatment outcomes. By addressing the antibiotic stewardship priorities outlined by the NIH and the CDC, her lab produced preliminary data suggesting that antibiotic treatment leads to a microbial shift towards healthier communities, supporting the underlying hypothesis. Her team recently showed that systemic antibiotics are widely prescribed during initial periodontal treatment without clinical practice guidelines related to adjunct antibiotics. Recently, her team developed a new line of research focusing on the intersection of sex and gender in oral inflammatory diseases. They have produced data that highlights the lack of adherence to reporting guidelines as it pertains to sex and gender in RCTs in periodontology. Therefore, her lab is focusing on better understanding sexual dimorphism in periodontitis to explain disease disparities. Dr. Ioannidou is passionate about rigor and transparency in clinical research and is a proponent of high-quality scientific reporting and clinical trial registration.
Dr. Ioannidou is a founding member of the IADR Women in Science Network. She served as the Associate Editor of the JDR Clinical and Translational Research until June 2023. She is currently the AADOCR President-elect (2022-2026). She has served as an ADA Council on Scientific Affairs member. She is the Task Force on Design and Analysis in Oral Health Research's Executive Director on Design and Analysis in Oral Health Research. She is an AADOCR (2018) and AAAS (2022) Fellow. Since July 1st, 2023, Dr. Ioannidou serves as the Editor-in-Chief of the two AAP Journals: Journal of Periodontology and the Clinical Advances in Periodontics.
Awards
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- Fellow, AAAS, 2021
- Fellow, American Association for Dental Research, 2018
- ADEA Leadership Institute Fellow, ADEA, 2016
- Mentor Award, IADR British Dental Journal, 2013
- Best Reviewer Award, Journal of Dental Research, 2011
- P. Robinson Outstanding Faculty Award, UCONN School of Dental Medicine, 2009
- Tarrson Fellowship, American Academy of Periodontology, 2008
- Neil Chilton Award, American Association for Dental Research, 2008
- Ruth L. Kirschstein National Research Award, NIH, 2008
- Outstanding Teacher Award, American Academy of Periodontology, 2007
- Faculty Development Award, UCONN School of Dental Medicine, 2007
Education & Training
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- Certificate Clinical Research University of Washington 08/2008
- MDSc Dental Science University of Connecticut 06/1999
- Certificate Periodontology University of Connecticut 06/1999
- DMD Dentistry Aristotle University of Thessaloniki 1995
Publications (66)
Top publication keywords:
PeriodontitisObservational Studies as TopicChecklistPeriodontal DiseasesSocieties, DentalDental ScalingOral HygieneDental Implantation, EndosseousChronic PeriodontitisOral HealthDental ResearchDentistsDentistryKidney Failure, ChronicDental Caries
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A Mentoring Network for Diversity in Dental, Oral, and Craniofacial Research.
Journal of dental research 2024 Herren SS, Ioannidou E, Drake D, Bernstein E, Mickel N, Fox CH -
The OHStat guidelines for reporting observational studies and clinical trials in oral health research: manuscript checklist.
The Angle orthodontist 2024 Best AM, Lang TA, Greenberg BL, Gunsolley JC, Ioannidou E, Task Force on Design and Analysis in Oral Health Research -
The OHStat Guidelines for Reporting Observational Studies and Clinical Trials in Oral Health Research: Manuscript Checklist.
Journal of endodontics 2024 Best AM, Lang TA, Greenberg BL, Gunsolley JC, Ioannidou E, Task Force on Design and Analysis in Oral Health Research -
The OHStat Guidelines for Reporting Observational Studies and Clinical Trials in Oral Health Research: Explanation and Elaboration.
JDR clinical and translational research 2024 Best AM, Lang TA, Greenberg BL, Gunsolley JC, Ioannidou E, Task Force on Design and Analysis in Oral Health Research -
The OHStat Guidelines for Reporting Observational Studies and Clinical Trials in Oral Health Research: Manuscript Checklist.
Journal of dental research 2024 Best AM, Lang TA, Greenberg BL, Gunsolley JC, Ioannidou E, Task Force on Design and Analysis in Oral Health Research
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The OHStat Guidelines for Reporting Observational Studies and Clinical Trials in Oral Health Research: explanation and elaboration.
Journal of the American Dental Association (1939) 2024 Best AM, Lang TA, Greenberg BL, Gunsolley JC, Ioannidou E, Task Force on Design and Analysis in Oral Health Research -
The OHStat Guidelines for Reporting Observational Studies and Clinical Trials in Oral Health Research: manuscript checklist.
Journal of the American Dental Association (1939) 2024 Best AM, Lang TA, Greenberg BL, Gunsolley JC, Ioannidou E, Task Force on Design and Analysis in Oral Health Research -
The Oral Health Statistical Guidelines for Reporting Observational Studies and Clinical Trials in Oral Health Research: Manuscript Checklist.
Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons 2024 Best AM, Lang TA, Greenberg BL, Gunsolley JC, Ioannidou E, Task Force on Design and Analysis in Oral Health Research -
The Oral Health Statistics Guidelines for Reporting Observational Studies and Clinical Trials in Oral Health Research: Explanation and Elaboration.
Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons 2024 Best AM, Lang TA, Greenberg BL, Gunsolley JC, Ioannidou E, Task Force on Design and Analysis in Oral Health Research -
Fistula first, catheter last: can the mouth be second?
Frontiers in nephrology 2024 Parsegian K, Himmelfarb J, Fares G, Ioannidou E -
A retrospective analysis of the role of age and sex in outcomes of non-surgical periodontal therapy at a single academic dental center.
Scientific reports 2024 Angelov N, Soldatos N, Ioannidou E, Carter TC, Shimpi N, Applegate J, Kookal KK, Parsegian K -
Sex as a Biological Variable in Oral Diseases: Evidence and Future Prospects.
Journal of dental research 2023 Sangalli L, Souza LC, Letra A, Shaddox L, Ioannidou E -
Teledentistry adoption and applications: An American Dental Association Clinical Evaluators Panel survey.
Journal of the American Dental Association (1939) 2023 Howell SEI, Kumar P, da Costa J, Haraszthy V, Ioannidou E, MacDonnell W, Tenuta LMA, Frazier K, Rockman R, Vinh R, Council on Scientific Affairs -
Perception of COVID-19 pandemic restrictions on dental researchers.
Journal of dental education 2022 De Souza GM, Tiwari T, Fox CH, Miguez PA, Letra A, Geisinger ML, Patel M, Shaddox L, Ioannidou E -
Lack of attention to sex and gender in periodontitis-related randomized clinical trials: A meta-research study.
Journal of clinical periodontology 2022 Michelson C, Al-Abedalla K, Wagner J, Swede H, Bernstein E, Ioannidou E -
Antibiotic prescription patterns among US general dentists and periodontists.
Journal of the American Dental Association (1939) 2022 Ioannidou E, Geurs N, Lipman R, Araujo MWB, Elkareh J, Engebretson S, Eber R, Oates T, Diaz P, Spino C -
The biological sex lens on early orthopaedic treatment duration and outcomes in Class III orthodontic patients: a systematic review.
European journal of orthodontics 2022 Arqub SA, Al-Zubi K, Iverson MG, Ioannidou E, Uribe F -
Association between periodontitis and chronic kidney disease.
Periodontology 2000 2022 Parsegian K, Randall D, Curtis M, Ioannidou E -
Woman authorship in pre-print versus peer-reviewed oral health-related publications: A two-year observational study.
PloS one 2021 Rajendran L, Khandelwal N, Feine J, Ioannidou E -
Unusual Findings in Trials Evaluating Adjuncts to Scaling and Root Planing: Meta-analysis (Part 1).
JDR clinical and translational research 2021 Gunsolley JC, Al-Abedalla K, Shaqman M, Ioannidou E -
Unusual Findings in Trials Evaluating Adjuncts to Scaling and Root Planing: Reporting Quality (Part 2).
JDR clinical and translational research 2021 Al-Abedalla K, Gunsolley JC, Shaqman M, Ioannidou E -
Inclusion and diversity.
Journal of the American Dental Association (1939) 2021 Ioannidou E, Bernstein E -
COVID-2019 among dentists in the United States: A 6-month longitudinal report of accumulative prevalence and incidence.
Journal of the American Dental Association (1939) 2021 Araujo MWB, Estrich CG, Mikkelsen M, Morrissey R, Harrison B, Geisinger ML, Ioannidou E, Vujicic M -
Antibiotic prescribing at a periodontal residency practice in Connecticut.
Journal of periodontology 2021 McKenna AM, Ioannidou E, Banach DB -
Estimating COVID-19 prevalence and infection control practices among US dentists.
Journal of the American Dental Association (1939) 2020 Estrich CG, Mikkelsen M, Morrissey R, Geisinger ML, Ioannidou E, Vujicic M, Araujo MWB -
Black Lives Matter Is About More Than Police Behavior.
JDR clinical and translational research 2020 Ioannidou E, Feine JS -
Reporting quality and spin in abstracts of randomized clinical trials of periodontal therapy and cardiovascular disease outcomes.
PloS one 2020 Shaqman M, Al-Abedalla K, Wagner J, Swede H, Gunsolley JC, Ioannidou E -
Oral Health Is About More Than Clean Teeth.
JDR clinical and translational research 2020 Ioannidou E, Feine JS -
Celebrating the IADR's Women Pioneers: Pathways for a New Century of Success.
Advances in dental research 2019 D'Souza RN, Ioannidou E, Tiwari T -
Empowering Women Researchers in the New Century: IADR's Strategic Direction.
Advances in dental research 2019 Ioannidou E, Letra A, Shaddox LM, Teles F, Ajiboye S, Ryan M, Fox CH, Tiwari T, D'Souza RN -
Gender Inequalities in the Dental Workforce: Global Perspectives.
Advances in dental research 2019 Tiwari T, Randall CL, Cohen L, Holtzmann J, Webster-Cyriaque J, Ajiboye S, Schou L, Wandera M, Ikeda K, Fidela de Lima Navarro M, Feres M, Abdellatif H, Al-Madi E, Tubert-Jeannin S, Fox CH, Ioannidou … -
Immediate versus delayed loading of mandibular implant-retained overdentures: A 60-month follow-up of a randomized clinical trial.
Journal of clinical periodontology 2019 Salman A, Thacker S, Rubin S, Dhingra A, Ioannidou E, Schincaglia GP -
Success and Responsibility.
JDR clinical and translational research 2019 Feine JS, Ioannidou E -
Novel PAradigm to improve Inflammatory burden in end stage Renal disease (rePAIR): study protocol for a randomized controlled trial.
Trials 2018 Trivedi R, Fares G, Nunez VB, Campbell R, Clement M, Burleson J, Himmelfarb J, Ioannidou E -
Task Force on Design and Analysis in Oral Health Research: Host-Microbiome Interactions in Dysbiosis.
JDR clinical and translational research 2017 Van Dyke TE, Diaz PI, Moutsopoulos N, Alekseyenko AV, Ioannidou E -
The Sex and Gender Intersection in Chronic Periodontitis.
Frontiers in public health 2017 Ioannidou E -
A bi-level intervention to improve oral hygiene of older and disabled adults in low-income housing: results of a pilot study.
Community dental health 2016 Reisine S, Schensul JJ, Goldblatt R, Radda K, Foster-Bey C, Acosta-Glynn C, Miron-Carcamo L, Ioannidou E -
Marginal Bone Response Around Immediate- and Delayed-Loading Implants Supporting a Locator-Retained Mandibular Overdenture: A Randomized Controlled Study.
The International journal of oral & maxillofacial implants 2016 Schincaglia GP, Rubin S, Thacker S, Dhingra A, Trombelli L, Ioannidou E -
Correction: Microbiome Profiles in Periodontitis in Relation to Host and Disease Characteristics.
PloS one 2016 Hong BY, Furtado Araujo MV, Strausbaugh LD, Terzi E, Ioannidou E, Diaz PI -
End stage renal disease as a modifier of the periodontal microbiome.
BMC nephrology 2015 Araújo MV, Hong BY, Fava PL, Khan S, Burleson JA, Fares G, Samson W, Strausbaugh LD, Diaz PI, Ioannidou E -
Microbiome profiles in periodontitis in relation to host and disease characteristics.
PloS one 2015 Hong BY, Furtado Araujo MV, Strausbaugh LD, Terzi E, Ioannidou E, Diaz PI -
Under-representation of women on dental journal editorial boards.
PloS one 2015 Ioannidou E, Rosania A -
Non-surgical and supportive periodontal therapy: predictors of compliance.
Journal of clinical periodontology 2014 Delatola C, Adonogianaki E, Ioannidou E -
Tooth loss strongly associates with malnutrition in chronic kidney disease.
Journal of periodontology 2013 Ioannidou E, Swede H, Fares G, Himmelfarb J -
Gender equity in dental academics: gains and unmet challenges.
Journal of dental research 2013 Ioannidou E, D'Souza RN, Macdougall MJ -
Transplantation-associated long-term immunosuppression promotes oral colonization by potentially opportunistic pathogens without impacting other members of the salivary bacteriome.
Clinical and vaccine immunology : CVI 2013 Diaz PI, Hong BY, Frias-Lopez J, Dupuy AK, Angeloni M, Abusleme L, Terzi E, Ioannidou E, Strausbaugh LD, Dongari-Bagtzoglou A -
Response to the review by Fisher and Ma.
The journal of evidence-based dental practice 2013 Ioannidou E, Swede H, Dongari-Bagtzoglou A -
Periodontitis associated with chronic kidney disease among Mexican Americans.
Journal of public health dentistry 2012 Ioannidou E, Hall Y, Swede H, Himmelfarb J -
Periodontitis predicts elevated C-reactive protein levels in chronic kidney disease.
Journal of dental research 2011 Ioannidou E, Swede H, Dongari-Bagtzoglou A -
Disparities in periodontitis prevalence among chronic kidney disease patients.
Journal of dental research 2011 Ioannidou E, Swede H -
Periodontitis case definition affects the association with renal function in kidney transplant recipients.
Oral diseases 2010 Ioannidou E, Shaqman M, Burleson J, Dongari-Bagtzoglou A -
Periodontitis and inflammatory markers in transplant recipients.
Journal of periodontology 2010 Shaqman M, Ioannidou E, Burleson J, Hull D, Dongari-Bagtzoglou A -
Increased levels of proinflammatory cytokines in children with family history of coronary artery disease.
Clinical cardiology 2010 E L, Fragakis N, Ioannidou E, Bounda A, Theodoridou S, Klonizakis P, Garipidou V -
Oral Candida infection and colonization in solid organ transplant recipients.
Oral microbiology and immunology 2009 Dongari-Bagtzoglou A, Dwivedi P, Ioannidou E, Shaqman M, Hull D, Burleson J -
Implant failure predictors in the posterior maxilla: a retrospective study of 273 consecutive implants.
Journal of periodontology 2008 Huynh-Ba G, Friedberg JR, Vogiatzi D, Ioannidou E -
Dental students' attitudes toward treating diverse patients: effects of a cross-cultural patient-instructor program.
Journal of dental education 2008 Wagner J, Arteaga S, D'Ambrosio J, Hodge C, Ioannidou E, Pfeiffer CA, Reisine S -
Letter to the Editor: Authors' Response to Pitiphat et al.
Journal of periodontology 2007 Ioannidou E, Malekzadeh T, Dongari-Bagtzoglou A -
Elevated serum interleukin-6 (IL-6) in solid-organ transplant recipients is positively associated with tissue destruction and IL-6 gene expression in the periodontium.
Journal of periodontology 2006 Ioannidou E, Kao D, Chang N, Burleson J, Dongari-Bagtzoglou A -
Effect of periodontal treatment on serum C-reactive protein levels: a systematic review and meta-analysis.
Journal of periodontology 2006 Ioannidou E, Malekzadeh T, Dongari-Bagtzoglou A -
Therapeutic modulation of growth factors and cytokines in regenerative medicine.
Current pharmaceutical design 2006 Ioannidou E -
Does loading time affect implant survival? A meta-analysis of 1,266 implants.
Journal of periodontology 2005 Ioannidou E, Doufexi A -
Gingival overgrowth in children: epidemiology, pathogenesis, and complications. A literature review.
Journal of periodontology 2005 Doufexi A, Mina M, Ioannidou E -
Twelve-year follow-up of an autogenous mandibular canine transplant.
Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics 2003 Ioannidou E, Makris GP -
Osteotome sinus floor elevation and simultaneous, non-submerged implant placement: case report and literature review.
Journal of periodontology 2000 Ioannidou E, Dean JW -
Anaerobic bacteria in jaw cysts.
The British journal of oral & maxillofacial surgery 1988 Iatrou IA, Legakis N, Ioannidou E, Patrikiou A -
[The role of Bacteroides melaninogenicus in periodontitis].
Stomatologia 1983 Andronikaki AG, Ioannidou E, Diamanti-Kipioti A, Mitsis FI