Edward Chu, MD
HS Clinical Professor
Pediatrics
School of Medicine

Publications (75)

Top publication keywords:
EndophthalmitisTrifluridineUracilCancer Care FacilitiesPostoperative HemorrhageAdvance Care PlanningTiclopidineDNA Mismatch RepairCoronavirus InfectionsColorectal NeoplasmsPneumonia, ViralColonic NeoplasmsNeoplasmsMedical OncologyMicrosatellite Instability

• Associations of Health Care Utilization and Therapeutic Alliance in Patients with Advanced Cancer.
  Journal of palliative medicine 2024 Bell SG, Althouse AD, Belin SC, Arnold RM, Smith KJ, White DB, Chu E, Schenker Y, Thomas TH
• Quassinoid analogs exert potent antitumor activity via reversible protein biosynthesis inhibition in human colorectal cancer.
  Biochemical pharmacology 2023 Wei N, Burnett J, Crocker DL, Huang Y, Li S, Wipf P, Chu E, Schmitz JC
• Primary Palliative Care Improves Uptake of Advance Care Planning Among Patients With Advanced Cancers.
  Journal of the National Comprehensive Cancer Network : JNCCN 2023 Cohen MG, Althouse AD, Arnold RM, White D, Chu E, Rosenzweig M, Smith KJ, Schenker Y
• Examining Caregiver Outcomes in the CONNECT Intervention for Patients With Advanced Cancer.
  Journal of pain and symptom management 2022 Semere W, Althouse AD, Arnold R, White D, Smith TJ, Chu E, Rosenzweig MQ, Schenker Y
• Symptom Burden and Shared Care Planning in an Oncology Nurse-Led Primary Palliative Care Intervention (CONNECT) for Patients with Advanced Cancer.
  Journal of palliative medicine 2022 Mitchell CJ, Althouse A, Feldman R, Arnold RM, Rosenzweig M, Smith K, Chu E, White D, Smith T, Schenker Y

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• Burnout Among Oncology Nurses: The Effects of Providing a Primary Palliative Care Intervention Using CONNECT Protocol.
  Clinical journal of oncology nursing 2022 Cohen JB, Reiser VL, Althouse AD, Resick JM, Chu E, Smith TJ, Arnold RM, Rosenzweig MQ, Schenker Y
• Framework for opioid stigma in cancer pain.
  Pain 2022 Bulls HW, Chu E, Goodin BR, Liebschutz JM, Wozniak A, Schenker Y, Merlin JS
• Hope and advance care planning in advanced cancer: Is there a relationship?
  Cancer 2021 Cohen MG, Althouse AD, Arnold RM, Bulls HW, White DB, Chu E, Rosenzweig MQ, Smith KJ, Schenker Y
• Effects of an Oncology Nurse-Led, Primary Palliative Care Intervention (CONNECT) on Illness Expectations Among Patients With Advanced Cancer.
  JCO oncology practice 2021 Sigler LE, Althouse AD, Thomas TH, Arnold RM, White D, Smith TJ, Chu E, Rosenzweig M, Smith KJ, Schenker Y
• How does the level of pulmonary venous isolation compare between pulsed field ablation and thermal energy ablation (radiofrequency, cryo, or laser)?
  Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 2021 Kawamura I, Neuzil P, Shivamurthy P, Kuroki K, Lam J, Musikantow D, Chu E, Turagam MK, Minami K, Funasako M, Petru J, Choudry S, Miller MA, Langan MN, Whang W, Dukkipati SR, Koruth JS, Reddy VY
• The Effects of Hyperbaric Oxygen Therapy in Patients with Central Retinal Artery Occlusion: A Retrospective Study, Systematic Review, and Meta-analysis.
  Korean journal of ophthalmology : KJO 2021 Rosignoli L, Chu ER, Carter JE, Johnson DA, Sohn JH, Bahadorani S
• Effect of an Oncology Nurse-Led Primary Palliative Care Intervention on Patients With Advanced Cancer: The CONNECT Cluster Randomized Clinical Trial.
  JAMA internal medicine 2021 Schenker Y, Althouse AD, Rosenzweig M, White DB, Chu E, Smith KJ, Resick JM, Belin S, Park SY, Smith TJ, Bakitas MA, Arnold RM
• Protective Role of 360° Laser Retinopexy in Patients with Rhegmatogenous Retinal Detachment: a Systematic Review and Meta-analysis.
  Korean journal of ophthalmology : KJO 2021 Soekamto C, Chu ER, Johnson DA, Sohn JH, Bahadorani S
• Barriers and financial impact of same-day discharge after atrial fibrillation ablation.
  Pacing and clinical electrophysiology : PACE 2021 Chu E, Zhang C, Musikantow DR, Turagam MK, Langan N, Sofi A, Choudry S, Syros G, Miller MA, Koruth JS, Whang W, Dukkipati SR, Reddy VY
• Stronger therapeutic alliance is associated with better quality of life among patients with advanced cancer.
  Psycho-oncology 2021 Thomas T, Althouse A, Sigler L, Arnold R, Chu E, White DB, Rosenzweig M, Smith K, Smith TJ, Schenker Y
• Atrial Fibrillation in Patients Hospitalized With COVID-19: Incidence, Predictors, Outcomes, and Comparison to Influenza.
  JACC. Clinical electrophysiology 2021 Musikantow DR, Turagam MK, Sartori S, Chu E, Kawamura I, Shivamurthy P, Bokhari M, Oates C, Zhang C, Pumill C, Malick W, Hashemi H, Ruiz-Maya T, Hadley MB, Gandhi J, Sperling D, Whang W, Koruth JS, …
• The Association Between Area Deprivation Index and Patient-Reported Outcomes in Patients with Advanced Cancer.
  Health equity 2021 Rosenzweig MQ, Althouse AD, Sabik L, Arnold R, Chu E, Smith TJ, Smith K, White D, Schenker Y
• Poor patient health is associated with higher caregiver burden for older adults with advanced cancer.
  Journal of geriatric oncology 2021 Semere W, Althouse AD, Rosland AM, White D, Arnold R, Chu E, Smith TJ, Schenker Y
• Malignant Arrhythmias in Patients With COVID-19: Incidence, Mechanisms, and Outcomes.
  Circulation. Arrhythmia and electrophysiology 2020 Turagam MK, Musikantow D, Goldman ME, Bassily-Marcus A, Chu E, Shivamurthy P, Lampert J, Kawamura I, Bokhari M, Whang W, Bier BA, Malick W, Hashemi H, Miller MA, Choudry S, Pumill C, Ruiz-Maya T, …
• Relationships Between Advanced Cancer Patients' Worry About Dying and Illness Understanding, Treatment Preferences, and Advance Care Planning.
  Journal of pain and symptom management 2020 Rodenbach RA, Althouse AD, Schenker Y, Smith TJ, Chu E, White DB, Bakitas M, Arnold RM
• Syncope and presyncope in patients with COVID-19.
  Pacing and clinical electrophysiology : PACE 2020 Oates CP, Turagam MK, Musikantow D, Chu E, Shivamurthy P, Lampert J, Kawamura I, Bokhari M, Whang W, Miller MA, Choudry S, Langan N, Sofi A, Dukkipati SR, Reddy VY, Koruth JS
• Patient-centered and efficacious advance care planning in cancer: Protocol and key design considerations for the PEACe-compare trial.
  Contemporary clinical trials 2020 Resick JM, Arnold RM, Sudore RL, Farrell D, Belin S, Althouse AD, Ferrell B, Hammes BJ, Chu E, White DB, Rak KJ, Schenker Y
• Treatment of Colorectal Cancer and Other GI Cancers in the COVID-19 Pandemic.
  Clinical colorectal cancer 2020 Chu E
• The UPMC Hillman Cancer Center Approach to the Management of Colorectal Cancer During the COVID-19 Pandemic Era.
  Clinical colorectal cancer 2020 Lee JJ, Chu E
• Is Advance Care Planning Associated With Decreased Hope in Advanced Cancer?
  JCO oncology practice 2020 Cohen MG, Althouse AD, Arnold RM, Bulls HW, White D, Chu E, Rosenzweig M, Smith K, Schenker Y
• Phase 1 study of veliparib (ABT-888), a poly (ADP-ribose) polymerase inhibitor, with carboplatin and paclitaxel in advanced solid malignancies.
  Cancer chemotherapy and pharmacology 2019 Appleman LJ, Beumer JH, Jiang Y, Lin Y, Ding F, Puhalla S, Swartz L, Owonikoko TK, Donald Harvey R, Stoller R, Petro DP, Tawbi HA, Argiris A, Strychor S, Pouquet M, Kiesel B, Chen AP, Gandara D, …
• Treatment of central serous chorioretinopathy with topical NSAIDs.
  Clinical ophthalmology (Auckland, N.Z.) 2019 Bahadorani S, Maclean K, Wannamaker K, Chu ER, Gresores N, Sohn JH, Diaz-Rohena R, Singer MA
• The effects of temporary intraocular pressure spikes after intravitreal dexamethasone implantation on the retinal nerve fiber layer.
  Clinical ophthalmology (Auckland, N.Z.) 2019 Wannamaker KW, Kenny S, Das R, Mendlovitz A, Comstock JM, Chu ER, Bahadorani S, Gresores NJ, Beck KD, Krambeer CJ, Kermany DS, Diaz-Rohena R, Nolan DP, Sohn JH, Singer MA
• Standardization of Inpatient CPR Status Discussions and Documentation Within the Division of Hematology-Oncology at UPMC Shadyside: Results From PDSA Cycles 1 and 2.
  Journal of oncology practice 2019 Garcia CA, Bhatnagar M, Rodenbach R, Chu E, Marks S, Graham-Pardus A, Kriner J, Winfield M, Minnier C, Leahy J, Hanchett S, Baird E, Arnold RM, Levenson JE
• Recent Advances in the Clinical Development of Immune Checkpoint Blockade Therapy for Mismatch Repair Proficient (pMMR)/non-MSI-H Metastatic Colorectal Cancer.
  Clinical colorectal cancer 2018 Lee JJ, Chu E
• Total Outflow Facility in Live C57BL/6 Mice of Different Age.
  Biomedicine hub 2017 Yelenskiy A, Ko MK, Chu ER, Gonzalez JM, Siegmund K, Tan JC
• State of the Science: Cancer Complementary and Alternative Medicine Therapeutics Research-NCI Strategic Workshop Highlights of Discussion Report.
  Journal of the National Cancer Institute. Monographs 2017 Xi D, Bao T, Chen Q, Chen S, Cheng YC, Cullen J, Frank DA, Friedberg JW, Kronish I, Lee JE, Levine M, Li P, Li S, Lu W, Mao JJ, O'Keefe S, Rubinstein L, Shah MA, Standish L, Paller CJ, Chu E
• LC-MS/MS assay for the quantitation of the ATR kinase inhibitor VX-970 in human plasma.
  Journal of pharmaceutical and biomedical analysis 2017 Kiesel BF, Scemama J, Parise RA, Villaruz L, Iffland A, Doyle A, Ivy P, Chu E, Bakkenist CJ, Beumer JH
• LC-MS/MS assay for the quantitation of the ribonucleotide reductase inhibitor triapine in human plasma.
  Journal of pharmaceutical and biomedical analysis 2017 Matsumoto J, Kiesel BF, Parise RA, Guo J, Taylor S, Huang M, Eiseman JL, Ivy SP, Kunos C, Chu E, Beumer JH
• A Pilot Trial of Early Specialty Palliative Care for Patients with Advanced Pancreatic Cancer: Challenges Encountered and Lessons Learned.
  Journal of palliative medicine 2017 Schenker Y, Bahary N, Claxton R, Childers J, Chu E, Kavalieratos D, King L, Lembersky B, Tiver G, Arnold RM
• Esophageal Damage During Epicardial Ventricular Tachycardia Ablation.
  JACC. Clinical electrophysiology 2017 Koruth JS, Chu EW, Bhardwaj R, Dukkipati S, Reddy VY
• Phase I study of veliparib in combination with gemcitabine.
  Cancer chemotherapy and pharmacology 2017 Stoller R, Schmitz JC, Ding F, Puhalla S, Belani CP, Appleman L, Lin Y, Jiang Y, Almokadem S, Petro D, Holleran J, Kiesel BF, Ken Czambel R, Carneiro BA, Kontopodis E, Hershberger PA, Rachid M, Chen A…
• Adjuvant Chemotherapy for Stage II Colon Cancer: The Debate Goes On.
  Journal of oncology practice 2017 Lee JJ, Chu E
• Natural History of Conversion of Leber's Hereditary Optic Neuropathy: A Prospective Case Series.
  Ophthalmology 2017 Hwang TJ, Karanjia R, Moraes-Filho MN, Gale J, Tran JS, Chu ER, Salomao SR, Berezovsky A, Belfort R, Moraes MN, Sadun F, DeNegri AM, La Morgia C, Barboni P, Ramos CDVF, Chicani CF, Quiros PA, Carelli …
• Adherence, Dosing, and Managing Toxicities With Trifluridine/Tipiracil (TAS-102).
  Clinical colorectal cancer 2017 Lee JJ, Chu E
• Systemic Therapy for Metastatic Colorectal Cancer: From Current Standards to Future Molecular Targeted Approaches.
  American Society of Clinical Oncology educational book. American Society of Clinical Oncology. Annual Meeting 2017 Atreya CE, Yaeger R, Chu E
• Correcting Finger Counting to Snellen Acuity.
  Neuro-ophthalmology (Aeolus Press) 2016 Karanjia R, Hwang TJ, Chen AF, Pouw A, Tian JJ, Chu ER, Wang MY, Tran JS, Sadun AA
• Tyrosine Kinase and Mammalian Target of Rapamycin Inhibitors in the Treatment of Advanced Renal Cell Carcinoma: Practical Clinical Implications of Pharmacologic Features.
  Clinical genitourinary cancer 2016 Parikh RA, Appleman LJ, Beumer JH, Matczak E, Chu E
• Human mass balance study of TAS-102 using (14)C analyzed by accelerator mass spectrometry.
  Cancer chemotherapy and pharmacology 2016 Lee JJ, Seraj J, Yoshida K, Mizuguchi H, Strychor S, Fiejdasz J, Faulkner T, Parise RA, Fawcett P, Pollice L, Mason S, Hague J, Croft M, Nugteren J, Tedder C, Sun W, Chu E, Beumer JH
• The evaluation of clopidogrel use in perioperative general surgery patients: a prospective randomized controlled trial.
  American journal of surgery 2015 Chu EW, Chernoguz A, Divino CM
• Cost-Effectiveness of Adjuvant Chemotherapy in the Treatment of Early-Stage Colon Cancer.
  Clinical colorectal cancer 2015 Soni A, Chu E
• Care management by oncology nurses to address palliative care needs: a pilot trial to assess feasibility, acceptability, and perceived effectiveness of the CONNECT intervention.
  Journal of palliative medicine 2014 Schenker Y, White D, Rosenzweig M, Chu E, Moore C, Ellis P, Nikolajski P, Ford C, Tiver G, McCarthy L, Arnold R
• What are cancer centers advertising to the public?: a content analysis.
  Annals of internal medicine 2014 Vater LB, Donohue JM, Arnold R, White DB, Chu E, Schenker Y
• The potential roles of hepatocyte growth factor (HGF)-MET pathway inhibitors in cancer treatment.
  OncoTargets and therapy 2014 Parikh RA, Wang P, Beumer JH, Chu E, Appleman LJ
• Sequencing of antiangiogenic agents in the treatment of metastatic colorectal cancer.
  Clinical colorectal cancer 2014 Lee JJ, Chu E
• Tissue-based imaging model of human trabecular meshwork.
  Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 2014 Chu ER, Gonzalez JM, Tan JC
• Oncologist factors that influence referrals to subspecialty palliative care clinics.
  Journal of oncology practice 2013 Schenker Y, Crowley-Matoka M, Dohan D, Rabow MW, Smith CB, White DB, Chu E, Tiver GA, Einhorn S, Arnold RM
• Calcium carbonate does not affect imatinib pharmacokinetics in healthy volunteers.
  Cancer chemotherapy and pharmacology 2013 Tawbi H, Christner SM, Lin Y, Johnson M, Mowrey ET, Cherrin C, Chu E, Lee JJ, Puhalla S, Stoller R, Appleman LR, Miller BM, Beumer JH
• Comparing EPI-743 treatment in siblings with Leber's hereditary optic neuropathy mt14484 mutation.
  Canadian journal of ophthalmology. Journal canadien d'ophtalmologie 2013 Chicani CF, Chu ER, Miller G, Kelman SE, Sadun AA
• The use of multidetector computed tomography in lower gastrointestinal bleeding.
  The American surgeon 2013 Chu EW, Harrington AN, Divino CM
• Smooth muscle features of mouse extraocular muscle.
  Clinical & experimental ophthalmology 2013 Ko MK, Chu ER, Tan JCh
• An illustrative case that demonstrates the importance of neuroimaging in midbrain corectopia.
  Canadian journal of ophthalmology. Journal canadien d'ophtalmologie 2013 Chu ER, Sadun AA
• Intraocular pressure measurement in acepromazine-sedated mice.
  Clinical & experimental ophthalmology 2013 Chu ER, Kim EK, Gonzalez JM, Ko MH, Liew EC, Tan JC
• LC-MS/MS assay for the quantitation of the HDAC inhibitor belinostat and five major metabolites in human plasma.
  Journal of pharmaceutical and biomedical analysis 2013 Kiesel BF, Parise RA, Tjørnelund J, Christensen MK, Loza E, Tawbi H, Chu E, Kummar S, Beumer JH
• Neuro-ophthalmology Safer Than MRI?
  Ophthalmology 2013 Sadun AA, Chu ER, Boisvert CJ
• Serum markers for predicting abdominal surgery outcomes in patients with cirrhosis.
  Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 2013 Harrington AN, Chu EW, Garg M, Divino CM
• The surgical management of active ulcerative colitis complicated by Clostridium difficile infection.
  Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 2012 Chu EW, Ecker BL, Garg M, Divino CM
• Liver fibrosis in elderly cadavers: localization of collagen types I, III, and IV, α-smooth muscle actin, and elastic fibers.
  Anatomical record (Hoboken, N.J. : 2007) 2012 Mak KM, Chu E, Lau KH, Kwong AJ
• Hepatic steatosis, fibrosis, and cancer in elderly cadavers.
  Anatomical record (Hoboken, N.J. : 2007) 2011 Mak KM, Kwong AJ, Chu E, Hoo NM
• An update on the current and emerging targeted agents in metastatic colorectal cancer.
  Clinical colorectal cancer 2011 Chu E
• Cessation of clopidogrel before major abdominal procedures.
  Archives of surgery (Chicago, Ill. : 1960) 2011 Chernoguz A, Telem DA, Chu E, Ozao-Choy J, Tammaro Y, Divino CM
• Concurrent central retinal artery occlusion and branch retinal vein occlusion in giant cell arteritis.
  Clinical ophthalmology (Auckland, N.Z.) 2010 Chu ER, Chen CS
• Another case of congenital pupillary-iris-lens membrane with goniodysgenesis.
  Journal of pediatric ophthalmology and strabismus 2010 Chu ER, Taranath DA
• Biology of colorectal cancer.
  Cancer journal (Sudbury, Mass.) 2010 Saif MW, Chu E
• Venom ophthalmia caused by venoms of spitting elapid and other snakes: Report of ten cases with review of epidemiology, clinical features, pathophysiology and management.
  Toxicon : official journal of the International Society on Toxinology 2010 Chu ER, Weinstein SA, White J, Warrell DA
• Is there any role for intravenous antivenom for snake venom ophthalmia?
  The Journal of emergency medicine 2009 Chu ER, White J, Weinstein S
• Terson Syndrome from a Significant Cerebral Infarct Occurring During the Peripartum Period.
  Journal of pediatric ophthalmology and strabismus 2009 Chu ER, Sandinha T, Lake S, Pater J
• Optic neuritis--more than a loss of vision.
  Australian family physician 2009 Chu ER, Chen CS
• Nineteen-year delayed-onset phacolytic uveitis following dislocation of the crystalline lens.
  Canadian journal of ophthalmology. Journal canadien d'ophtalmologie 2009 Chu ER, Durkin SR, Keembiyage RD, Nathan F, Raymond G
• Treatment of metastatic colorectal cancer: from cytotoxic agents to molecular agents and multitargeted strategies.
  Oncology (Williston Park, N.Y.) 2006 Saif MW, Kang SP, Chu E