Edward Chang, MD
Professor
Neurological Surgery
School of Medicine

Dr Chang specializes in advanced brain mapping methods to preserve crucial areas for speech and motor functions in the brain. He also has extensive experience with implantable devices that stimulate specific nerves to relieve seizure, movement, pain and other disorders.

Dr Chang's research focuses on the brain mechanisms for speech, movement and human emotion. He co-directs the Center for Neural Engineering and Prostheses, a collaborative enterprise of UCSF and the University of California, Berkeley. The center brings together experts in engineering, neurology and neurosurgery to develop state-of-the-art biomedical technology to restore function for patients with neurological disabilities such as paralysis and speech disorders.

Dr Chang earned his medical degree at UCSF, where he also completed a residency in neurosurgery. He was honored with the Blavatnik National Laureate for Life Sciences in 2015, in recognition of his contributions to deciphering the neural code of speech. Dr. Chang is the inaugural Bowes Biomedical Investigator at UCSF and HHMI Faculty Scholar. Dr Chang was inducted to the National Academy of Medicine in 2020.

• Anatomical registration of intracranial electrodes. Robust model-based localization and deformable smooth brain-shift compensation methods.
  Journal of neuroscience methods 2024 Blenkmann AO, Leske SL, Llorens A, Lin JJ, Chang EF, Brunner P, Schalk G, Ivanovic J, Larsson PG, Knight RT, Endestad T, Solbakk AK
• Intraoperative cortical stimulation mapping with laryngeal electromyography for the localization of human laryngeal motor cortex.
  Journal of neurosurgery 2024 Ammanuel SG, Kondapavulur S, Lu AY, Breshears JD, Clark JP, Silva AB, Chang EF
• Large-scale single-neuron speech sound encoding across the depth of human cortex.
  Nature 2023 Leonard MK, Gwilliams L, Sellers KK, Chung JE, Xu D, Mischler G, Mesgarani N, Welkenhuysen M, Dutta B, Chang EF
• "De novo replication repair deficient glioblastoma, IDH-wildtype" is a distinct glioblastoma subtype in adults that may benefit from immune checkpoint blockade.
  Acta neuropathologica 2023 Hadad S, Gupta R, Oberheim Bush NA, Taylor JW, Villanueva-Meyer JE, Young JS, Wu J, Ravindranathan A, Zhang Y, Warrier G, McCoy L, Shai A, Pekmezci M, Perry A, Bollen AW, Phillips JJ, Braunstein SE, …
• Dissecting neural computations in the human auditory pathway using deep neural networks for speech.
  Nature neuroscience 2023 Li Y, Anumanchipalli GK, Mohamed A, Chen P, Carney LH, Lu J, Wu J, Chang EF
• Neural control of lexical tone production in human laryngeal motor cortex.
  Nature communications 2023 Lu J, Li Y, Zhao Z, Liu Y, Zhu Y, Mao Y, Wu J, Chang EF
• Encoding of melody in the human auditory cortex.
  bioRxiv : the preprint server for biology 2023 Sankaran N, Leonard MK, Theunissen F, Chang EF
• Recommendations for promoting user agency in the design of speech neuroprostheses.
  Frontiers in human neuroscience 2023 Sankaran N, Moses D, Chiong W, Chang EF
• Interictal epileptiform discharges contribute to word-finding difficulty in epilepsy through multiple cognitive mechanisms.
  Epilepsia 2023 Silva AB, Leonard MK, Oganian Y, D'Esopo E, Krish D, Kopald B, Tran EB, Chang EF, Kleen JK
• Ictal EEG Source Imaging With Supplemental Electrodes.
  Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society 2023 Loube DK, Tan YL, Yoshii-Contreras J, Kleen J, Rao VR, Chang EF, Knowlton RC
• A Transcriptomic Comparative Study of Cranial Vasculature.
  Translational stroke research 2023 Zhang J, Ryu JY, Tirado SR, Dickinson LD, Abosch A, Aziz-Sultan MA, Boulos AS, Barrow DL, Batjer HH, Binyamin TR, Blackburn SL, Chang EF, Chen PR, Colby GP, Cosgrove GR, David CA, Day AL, Folkerth RD,…
• A high-performance neuroprosthesis for speech decoding and avatar control.
  Nature 2023 Metzger SL, Littlejohn KT, Silva AB, Moses DA, Seaton MP, Wang R, Dougherty ME, Liu JR, Wu P, Berger MA, Zhuravleva I, Tu-Chan A, Ganguly K, Anumanchipalli GK, Chang EF
• Flexible regulation of representations on a drifting manifold enables long-term stable complex neuroprosthetic control.
  bioRxiv : the preprint server for biology 2023 Natraj N, Seko S, Abiri R, Yan H, Graham Y, Tu-Chan A, Chang EF, Ganguly K
• Association of CDKN2A alterations with increased postoperative seizure risk after resection of brain metastases.
  Neurosurgical focus 2023 Cummins DD, Garcia JH, Nguyen MP, Saggi S, Chung JE, Goldschmidt E, Berger MS, Theodosopoulos PV, Chang EF, Daras M, Hervey-Jumper SL, Aghi MK, Morshed RA
• Genomic alterations associated with postoperative nodular leptomeningeal disease after resection of brain metastases.
  Journal of neurosurgery 2023 Morshed RA, Cummins DD, Nguyen MP, Saggi S, Vasudevan HN, Braunstein SE, Goldschmidt E, Chang EF, McDermott MW, Berger MS, Theodosopoulos PV, Daras M, Hervey-Jumper SL, Aghi MK
• Awake Craniotomy and Electrocorticography-Guided Extended Lesionectomy of Motor Cortex Cavernoma: 2-Dimensional Operative Video.
  Operative neurosurgery (Hagerstown, Md.) 2023 Raygor KP, Rinaldo L, Dubnicoff TB, Shih T, Chang EF, Abla AA
• Closed-Loop Neurostimulation for Biomarker-Driven, Personalized Treatment of Major Depressive Disorder.
  Journal of visualized experiments : JoVE 2023 Sellers KK, Khambhati AN, Stapper N, Fan JM, Rao VR, Scangos KW, Chang EF, Krystal AD
• Latent neural dynamics encode temporal context in speech.
  Hearing research 2023 Stephen EP, Li Y, Metzger S, Oganian Y, Chang EF
• Intracranial electrical stimulation of corticolimbic sites modulates arousal in humans.
  Brain stimulation 2023 Fan JM, Lee AM, Sellers KK, Woodworth K, Makhoul GS, Liu TX, Henderson C, Astudillo Maya DA, Martinez R, Zamanian H, Speidel BA, Khambhati AN, Rao VR, Sugrue LP, Scangos KW, Chang EF, Krystal AD
• Closed-loop neurostimulation for the treatment of psychiatric disorders.
  Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2023 Sellers KK, Cohen JL, Khambhati AN, Fan JM, Lee AM, Chang EF, Krystal AD
• Mismatched opioid prescription in patients discharged after neurological surgeries: a retrospective cohort study.
  Pain 2023 Campbell LJ, Mummaneni PV, Letchuman V, Langnas E, Agarwal N, Guan LS, Croci R, Vargas E, Reisner L, Bickler P, Chou D, Chang E, Guan Z
• First-in-human prediction of chronic pain state using intracranial neural biomarkers.
  Nature neuroscience 2023 Shirvalkar P, Prosky J, Chin G, Ahmadipour P, Sani OG, Desai M, Schmitgen A, Dawes H, Shanechi MM, Starr PA, Chang EF
• Future directions in psychiatric neurosurgery: Proceedings of the 2022 American Society for Stereotactic and Functional Neurosurgery meeting on surgical neuromodulation for psychiatric disorders.
  Brain stimulation 2023 Hitti FL, Widge AS, Riva-Posse P, Malone DA, Okun MS, Shanechi MM, Foote KD, Lisanby SH, Ankudowich E, Chivukula S, Chang EF, Gunduz A, Hamani C, Feinsinger A, Kubu CS, Chiong W, Chandler JA, …
• Anatomical registration of intracranial electrodes. Robust model-based localization and deformable smooth brain-shift compensation methods.
  bioRxiv : the preprint server for biology 2023 Blenkmann AO, Leske SL, Llorens A, Lin JJ, Chang E, Brunner P, Schalk G, Ivanovic J, Larsson PG, Knight RT, Endestad T, Solbakk AK
• Anatomical and behavioral correlates of auditory perception in developmental dyslexia.
  bioRxiv : the preprint server for biology 2023 Qi T, Mandelli ML, Pereira CLW, Wellman E, Bogley R, Licata AE, Chang EF, Oganian Y, Gorno-Tempini ML
• Grasp-specific high-frequency broadband mirror neuron activity during reach-and-grasp movements in humans.
  Cerebral cortex (New York, N.Y. : 1991) 2023 Dreyer AM, Michalke L, Perry A, Chang EF, Lin JJ, Knight RT, Rieger JW
• Glioblastoma remodelling of human neural circuits decreases survival.
  Nature 2023 Krishna S, Choudhury A, Keough MB, Seo K, Ni L, Kakaizada S, Lee A, Aabedi A, Popova G, Lipkin B, Cao C, Nava Gonzales C, Sudharshan R, Egladyous A, Almeida N, Zhang Y, Molinaro AM, Venkatesh HS, …
• Phase Alignment of Low-Frequency Neural Activity to the Amplitude Envelope of Speech Reflects Evoked Responses to Acoustic Edges, Not Oscillatory Entrainment.
  The Journal of neuroscience : the official journal of the Society for Neuroscience 2023 Oganian Y, Kojima K, Breska A, Cai C, Findlay A, Chang E, Nagarajan SS
• Vowel and formant representation in the human auditory speech cortex.
  Neuron 2023 Oganian Y, Bhaya-Grossman I, Johnson K, Chang EF
• Apraxia of speech with phonological alexia and agraphia following resection of the left middle precentral gyrus: illustrative case.
  Journal of neurosurgery. Case lessons 2023 Levy DF, Silva AB, Scott TL, Liu JR, Harper S, Zhao L, Hullett PW, Kurteff G, Wilson SM, Leonard MK, Chang EF
• Epileptiform discharges triggered with direct electrical stimulation for treatment-resistant depression: Factors that modulate risk and treatment considerations.
  Brain stimulation 2023 Fan JM, Khambhati AN, Sellers KK, Stapper N, Maya DA, Kunwar E, Henderson C, Sugrue LP, Scangos KW, Chang EF, Rao VR, Krystal AD
• Changes in intracranial neurophysiology associated with acute COVID-19 infection.
  Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology 2023 Sellers KK, Stapper N, Astudillo Maya DA, Henderson C, Khambhati AN, Fan JM, Rao VR, Scangos KW, Chang EF, Krystal AD
• CDKN2A/B co-deletion is associated with increased risk of local and distant intracranial recurrence after surgical resection of brain metastases.
  Neuro-oncology advances 2023 Morshed RA, Nguyen MP, Cummins DD, Saggi S, Young JS, Haddad AF, Goldschmidt E, Chang EF, McDermott MW, Berger MS, Theodosopoulos PV, Hervey-Jumper SL, Daras M, Aghi MK
• Identification of risk factors associated with leptomeningeal disease after resection of brain metastases.
  Journal of neurosurgery 2023 Morshed RA, Saggi S, Cummins DD, Molinaro AM, Young JS, Viner JA, Villanueva-Meyer JE, Goldschmidt E, Boreta L, Braunstein SE, Chang EF, McDermott MW, Berger MS, Theodosopoulos PV, Hervey-Jumper SL, …
• Interactive Effects of Molecular, Therapeutic, and Patient Factors on Outcome of Diffuse Low-Grade Glioma.
  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2023 Hervey-Jumper SL, Zhang Y, Phillips JJ, Morshed RA, Young JS, McCoy L, Lafontaine M, Luks T, Ammanuel S, Kakaizada S, Egladyous A, Gogos A, Villanueva-Meyer J, Shai A, Warrier G, Rice T, Crane J, …
• On-Call Junior Neurosurgery Residents Spend 9 hours of Their On-Call Shift Actively Using the Electronic Health Record.
  Neurosurgery 2022 Patel A, Mummaneni PV, Zheng J, Rosner BI, Thombley R, Sorour O, Theodosopoulos PV, Aghi MK, Berger MS, Chang EF, Chou D, Manley GT, DiGiorgio AM
• Intact speech perception after resection of dominant hemisphere primary auditory cortex for the treatment of medically refractory epilepsy: illustrative case.
  Journal of neurosurgery. Case lessons 2022 Hullett PW, Kandahari N, Shih TT, Kleen JK, Knowlton RC, Rao VR, Chang EF
• Somatic Variants in SVIL in Cerebral Aneurysms.
  Neurology. Genetics 2022 Lai PMR, Ryu JY, Park SC, Gross BA, Dickinson LD, Dagen S, Aziz-Sultan MA, Boulos AS, Barrow DL, Batjer HH, Blackburn S, Chang EF, Chen PR, Colby GP, Cosgrove GR, David CA, Day AL, Frerichs KU, …
• A Neurosurgical Functional Dissection of the Middle Precentral Gyrus during Speech Production.
  The Journal of neuroscience : the official journal of the Society for Neuroscience 2022 Silva AB, Liu JR, Zhao L, Levy DF, Scott TL, Chang EF
• Generalizable spelling using a speech neuroprosthesis in an individual with severe limb and vocal paralysis.
  Nature communications 2022 Metzger SL, Liu JR, Moses DA, Dougherty ME, Seaton MP, Littlejohn KT, Chartier J, Anumanchipalli GK, Tu-Chan A, Ganguly K, Chang EF
• Evaluating syntactic comprehension during awake intraoperative cortical stimulation mapping.
  Journal of neurosurgery 2022 Riva M, Wilson SM, Cai R, Castellano A, Jordan KM, Henry RG, Gorno Tempini ML, Berger MS, Chang EF
• Prospective genomically guided identification of "early/evolving" and "undersampled" IDH-wildtype glioblastoma leads to improved clinical outcomes.
  Neuro-oncology 2022 Zhang Y, Lucas CG, Young JS, Morshed RA, McCoy L, Oberheim Bush NA, Taylor JW, Daras M, Butowski NA, Villanueva-Meyer JE, Cha S, Wrensch M, Wiencke JK, Lee JC, Pekmezci M, Phillips JJ, Perry A, Bollen…
• Publisher Correction: State-dependent responses to intracranial brain stimulation in a patient with depression.
  Nature medicine 2022 Scangos KW, Makhoul GS, Sugrue LP, Chang EF, Krystal AD
• Impact of the COVID-19 Pandemic on Neurosurgical Transfers: A Single Tertiary Center Study.
  World neurosurgery 2022 Reihl SJ, Garcia JH, Morshed RA, Sankaran S, DiGiorgio A, Chou D, Theodosopoulos PV, Aghi MK, Berger MS, Chang EF, Mummaneni PV
• Dissociation of Broca's area from Broca's aphasia in patients undergoing neurosurgical resections.
  Journal of neurosurgery 2022 Andrews JP, Cahn N, Speidel BA, Chung JE, Levy DF, Wilson SM, Berger MS, Chang EF
• Modern intracranial electroencephalography for epilepsy localization with combined subdural grid and depth electrodes with low and improved hemorrhagic complication rates.
  Journal of neurosurgery 2022 Lee AT, Nichols NM, Speidel BA, Fan JM, Cajigas I, Knowlton RC, Chang EF
• Involvement of White Matter Language Tracts in Glioma: Clinical Implications, Operative Management, and Functional Recovery After Injury.
  Frontiers in neuroscience 2022 Aabedi AA, Young JS, Chang EF, Berger MS, Hervey-Jumper SL
• High-density single-unit human cortical recordings using the Neuropixels probe.
  Neuron 2022 Chung JE, Sellers KK, Leonard MK, Gwilliams L, Xu D, Dougherty ME, Kharazia V, Metzger SL, Welkenhuysen M, Dutta B, Chang EF
• Factors associated with preoperative and postoperative seizures in patients undergoing resection of brain metastases.
  Journal of neurosurgery 2022 Garcia JH, Morshed RA, Chung J, Millares Chavez MA, Sudhakar V, Saggi S, Avalos LN, Gallagher A, Young JS, Daras M, McDermott MW, Garcia PA, Chang EF, Aghi MK
• Network connectivity predicts effectiveness of responsive neurostimulation in focal epilepsy.
  Brain communications 2022 Fan JM, Lee AT, Kudo K, Ranasinghe KG, Morise H, Findlay AM, Kirsch HE, Chang EF, Nagarajan SS, Rao VR
• Harnessing the Power of Artificial Intelligence in Otolaryngology and the Communication Sciences.
  Journal of the Association for Research in Otolaryngology : JARO 2022 Wilson BS, Tucci DL, Moses DA, Chang EF, Young NM, Zeng FG, Lesica NA, Bur AM, Kavookjian H, Mussatto C, Penn J, Goodwin S, Kraft S, Wang G, Cohen JM, Ginsburg GS, Dawson G, Francis HW
• Decoding naturalistic affective behaviour from spectro-spatial features in multiday human iEEG.
  Nature human behaviour 2022 Bijanzadeh M, Khambhati AN, Desai M, Wallace DL, Shafi A, Dawes HE, Sturm VE, Chang EF
• A single-cell atlas of the normal and malformed human brain vasculature.
  Science (New York, N.Y.) 2022 Winkler EA, Kim CN, Ross JM, Garcia JH, Gil E, Oh I, Chen LQ, Wu D, Catapano JS, Raygor K, Narsinh K, Kim H, Weinsheimer S, Cooke DL, Walcott BP, Lawton MT, Gupta N, Zlokovic BV, Chang EF, Abla AA, …
• Recurrent Radiation-Induced Cavernous Malformation After Gamma Knife Stereotactic Radiosurgery for Brain Metastasis.
  Cureus 2022 Chew JJ, Sneed PK, Chang EF
• Left hemisphere dominance for bilateral kinematic encoding in the human brain.
  eLife 2022 Merrick CM, Dixon TC, Breska A, Lin J, Chang EF, King-Stephens D, Laxer KD, Weber PB, Carmena J, Thomas Knight R, Ivry RB
• Ethical commitments, principles, and practices guiding intracranial neuroscientific research in humans.
  Neuron 2022 Feinsinger A, Pouratian N, Ebadi H, Adolphs R, Andersen R, Beauchamp MS, Chang EF, Crone NE, Collinger JL, Fried I, Mamelak A, Richardson M, Rutishauser U, Sheth SA, Suthana N, Tandon N, Yoshor D, NIH…
• Postsurgical seizure outcome in temporal lobe epilepsy patients with normal or subtle, nonspecific MRI findings.
  Journal of neurosurgery 2021 González Otárula KA, Tan YL, Hall JA, Chang EF, Correa JA, Dubeau F, Sziklas V, Soucy JP, Guiot MC, Knowlton RC, Kobayashi E
• Practical Closed-Loop Strategies for Deep Brain Stimulation: Lessons From Chronic Pain.
  Frontiers in neuroscience 2021 Prosky J, Cagle J, Sellers KK, Gilron R, de Hemptinne C, Schmitgen A, Starr PA, Chang EF, Shirvalkar P
• Human intracranial recordings reveal distinct cortical activity patterns during invasive and non-invasive vagus nerve stimulation.
  Scientific reports 2021 Schuerman WL, Nourski KV, Rhone AE, Howard MA, Chang EF, Leonard MK
• Functional alterations in cortical processing of speech in glioma-infiltrated cortex.
  Proceedings of the National Academy of Sciences of the United States of America 2021 Aabedi AA, Lipkin B, Kaur J, Kakaizada S, Valdivia C, Reihl S, Young JS, Lee AT, Krishna S, Berger MS, Chang EF, Brang D, Hervey-Jumper SL
• Compartmentalized dynamics within a common multi-area mesoscale manifold represent a repertoire of human hand movements.
  Neuron 2021 Natraj N, Silversmith DB, Chang EF, Ganguly K
• Distributed Subnetworks of Depression Defined by Direct Intracranial Neurophysiology.
  Frontiers in human neuroscience 2021 Scangos KW, Khambhati AN, Daly PM, Owen LW, Manning JR, Ambrose JB, Austin E, Dawes HE, Krystal AD, Chang EF
• Prefrontal Physiomarkers of Anxiety and Depression in Parkinson's Disease.
  Frontiers in neuroscience 2021 de Hemptinne C, Chen W, Racine CA, Seritan AL, Miller AM, Yaroshinsky MS, Wang SS, Gilron R, Little S, Bledsoe I, San Luciano M, Katz M, Chang EF, Dawes HE, Ostrem JL, Starr PA
• Speech Computations of the Human Superior Temporal Gyrus.
  Annual review of psychology 2021 Bhaya-Grossman I, Chang EF
• Decoding Speech from Cortical Surface Electrical Activity. Reply.
  The New England journal of medicine 2021 Moses DA, Liu PM, Chang EF
• Facial pain and sensory outcomes following resection of tumors compressing the trigeminal nerve.
  Journal of neurosurgery 2021 Castro MRH, Magill ST, Morshed RA, Young JS, Braunstein SE, McDermott MW, Chang EF
• Closed-loop neuromodulation in an individual with treatment-resistant depression.
  Nature medicine 2021 Scangos KW, Khambhati AN, Daly PM, Makhoul GS, Sugrue LP, Zamanian H, Liu TX, Rao VR, Sellers KK, Dawes HE, Starr PA, Krystal AD, Chang EF
• Corrigendum: Proceedings of the Eighth Annual Deep Brain Stimulation Think Tank: Advances in Optogenetics, Ethical Issues Affecting DBS Research, Neuromodulatory Approaches for Depression, Adaptive Neurostimulation, and Emerging DBS Technologies.
  Frontiers in human neuroscience 2021 Vedam-Mai V, Deisseroth K, Giordano J, Lazaro-Munoz G, Chiong W, Suthana N, Langevin JP, Gill J, Goodman W, Provenza NR, Halpern CH, Shivacharan RS, Cunningham TN, Sheth SA, Pouratian N, Scangos KW, …
• Understanding Variable Motor Responses to Direct Electrical Stimulation of the Human Motor Cortex During Brain Surgery.
  Frontiers in surgery 2021 Aaronson DM, Martinez Del Campo E, Boerger TF, Conway B, Cornell S, Tate M, Mueller WM, Chang EF, Krucoff MO
• Learning nonnative speech sounds changes local encoding in the adult human cortex.
  Proceedings of the National Academy of Sciences of the United States of America 2021 Yi HG, Chandrasekaran B, Nourski KV, Rhone AE, Schuerman WL, Howard MA, Chang EF, Leonard MK
• Functional maps of direct electrical stimulation-induced speech arrest and anomia: a multicentre retrospective study.
  Brain : a journal of neurology 2021 Lu J, Zhao Z, Zhang J, Wu B, Zhu Y, Chang EF, Wu J, Duffau H, Berger MS
• Long-term brain network reorganization predicts responsive neurostimulation outcomes for focal epilepsy.
  Science translational medicine 2021 Khambhati AN, Shafi A, Rao VR, Chang EF
• Parallel and distributed encoding of speech across human auditory cortex.
  Cell 2021 Hamilton LS, Oganian Y, Hall J, Chang EF
• Thin-film microfabrication and intraoperative testing ofµECoG and iEEG depth arrays for sense and stimulation.
  Journal of neural engineering 2021 Sellers KK, Chung JE, Zhou J, Triplett MG, Dawes HE, Haque R, Chang EF
• A Review of Cortical and Subcortical Stimulation Mapping for Language.
  Neurosurgery 2021 Young JS, Lee AT, Chang EF
• Correlation of natural language assessment results with health-related quality of life in adult glioma patients.
  Journal of neurosurgery 2021 Ammanuel SG, Almeida NC, Kurteff G, Kakaizada S, Molinaro AM, Berger MS, Chang EF, Hervey-Jumper SL
• Patient specific prediction of temporal lobe epilepsy surgical outcomes.
  Epilepsia 2021 Benjumeda M, Tan YL, González Otárula KA, Chandramohan D, Chang EF, Hall JA, Bielza C, Larrañaga P, Kobayashi E, Knowlton RC
• Neuroprosthesis for Decoding Speech in a Paralyzed Person with Anarthria.
  The New England journal of medicine 2021 Moses DA, Metzger SL, Liu JR, Anumanchipalli GK, Makin JG, Sun PF, Chartier J, Dougherty ME, Liu PM, Abrams GM, Tu-Chan A, Ganguly K, Chang EF
• Analysis-rcs-data: Open-Source Toolbox for the Ingestion, Time-Alignment, and Visualization of Sense and Stimulation Data From the Medtronic Summit RC+S System.
  Frontiers in human neuroscience 2021 Sellers KK, Gilron R, Anso J, Louie KH, Shirvalkar PR, Chang EF, Little SJ, Starr PA
• Effects of anterior thalamic nuclei stimulation on hippocampal activity: Chronic recording in a patient with drug-resistant focal epilepsy.
  Epilepsy & behavior reports 2021 Silva AB, Khambhati AN, Speidel BA, Chang EF, Rao VR
• Bidirectional propagation of low frequency oscillations over the human hippocampal surface.
  Nature communications 2021 Kleen JK, Chung JE, Sellers KK, Zhou J, Triplett M, Lee K, Tooker A, Haque R, Chang EF
• Musical Hallucinations in Chronic Pain: The Anterior Cingulate Cortex Regulates Internally Generated Percepts.
  Frontiers in neurology 2021 Schmitgen A, Saal J, Sankaran N, Desai M, Joseph I, Starr P, Chang EF, Shirvalkar P
• Are preoperative chlorhexidine gluconate showers associated with a reduction in surgical site infection following craniotomy? A retrospective cohort analysis of 3126 surgical procedures.
  Journal of neurosurgery 2021 Ammanuel SG, Edwards CS, Chan AK, Mummaneni PV, Kidane J, Vargas E, D'Souza S, Nichols AD, Sankaran S, Abla AA, Aghi MK, Chang EF, Hervey-Jumper SL, Kunwar S, Larson PS, Lawton MT, Starr PA, …
• Proceedings of the Eighth Annual Deep Brain Stimulation Think Tank: Advances in Optogenetics, Ethical Issues Affecting DBS Research, Neuromodulatory Approaches for Depression, Adaptive Neurostimulation, and Emerging DBS Technologies.
  Frontiers in human neuroscience 2021 Vedam-Mai V, Deisseroth K, Giordano J, Lazaro-Munoz G, Chiong W, Suthana N, Langevin JP, Gill J, Goodman W, Provenza NR, Halpern CH, Shivacharan RS, Cunningham TN, Sheth SA, Pouratian N, Scangos KW, …
• Accuracy of omni-planar and surface casting of epileptiform activity for intracranial seizure localization.
  Epilepsia 2021 Kleen JK, Speidel BA, Baud MO, Rao VR, Ammanuel SG, Hamilton LS, Chang EF, Knowlton RC
• Development and Assessment of a Video-Based Intervention to Improve Rhinoplasty Informed Consent.
  Facial plastic surgery : FPS 2021 Hakimi AA, Standiford L, Chang E, Wong BJ
• Adaptive tracking of human ECoG network dynamics.
  Journal of neural engineering 2021 Ahmadipour P, Yang Y, Chang EF, Shanechi MM
• Human cortical encoding of pitch in tonal and non-tonal languages.
  Nature communications 2021 Li Y, Tang C, Lu J, Wu J, Chang EF
• Evidence of state-dependence in the effectiveness of responsive neurostimulation for seizure modulation.
  Brain stimulation 2021 Chiang S, Khambhati AN, Wang ET, Vannucci M, Chang EF, Rao VR
• State-dependent responses to intracranial brain stimulation in a patient with depression.
  Nature medicine 2021 Scangos KW, Makhoul GS, Sugrue LP, Chang EF, Krystal AD
• Operative Technique and Lessons Learned From Surgical Implantation of the NeuroPace Responsive Neurostimulation® System in 57 Consecutive Patients.
  Operative neurosurgery (Hagerstown, Md.) 2021 Krucoff MO, Wozny TA, Lee AT, Rao VR, Chang EF
• Data-Driven, Visual Framework for the Characterization of Aphasias Across Stroke, Post-resective, and Neurodegenerative Disorders Over Time.
  Frontiers in neurology 2020 Fan JM, Gorno-Tempini ML, Dronkers NF, Miller BL, Berger MS, Chang EF
• Brain2Char: a deep architecture for decoding text from brain recordings.
  Journal of neural engineering 2020 Sun P, Anumanchipalli GK, Chang EF
• Objective score from initial interview identifies patients with probable dissociative seizures.
  Epilepsy & behavior : E&B 2020 Kerr WT, Janio EA, Chau AM, Braesch CT, Le JM, Hori JM, Patel AB, Gallardo NL, Allas CH, Karimi AH, Dubey I, Sreenivasan SS, Bauirjan J, Hwang ES, Davis EC, D'Ambrosio SR, Al Banna M, Mazumder R, Wu T…
• Long-term pain outcomes in elderly patients with trigeminal neuralgia: comparison of first-time microvascular decompression and stereotactic radiosurgery.
  Neurosurgical focus 2020 Raygor KP, Lee AT, Nichols N, Wang DD, Ward MM, Barbaro NM, Chang EF
• A Deep Brain Stimulation Trial Period for Treating Chronic Pain.
  Journal of clinical medicine 2020 Shirvalkar P, Sellers KK, Schmitgen A, Prosky J, Joseph I, Starr PA, Chang EF
• Early seizure spread and epilepsy surgery: A systematic review.
  Epilepsia 2020 Andrews JP, Ammanuel S, Kleen J, Khambhati AN, Knowlton R, Chang EF
• Plug-and-play control of a brain-computer interface through neural map stabilization.
  Nature biotechnology 2020 Silversmith DB, Abiri R, Hardy NF, Natraj N, Tu-Chan A, Chang EF, Ganguly K
• Comparison of Stereotactic Radiosurgery and Radiofrequency Ablation for Trigeminal Neuralgia in Multiple Sclerosis Patients.
  Stereotactic and functional neurosurgery 2020 Lee AT, Raygor KP, Elefant F, Ward MM, Wang DD, Barbaro NM, Chang EF
• Cortical Encoding of Manual Articulatory and Linguistic Features in American Sign Language.
  Current biology : CB 2020 Leonard MK, Lucas B, Blau S, Corina DP, Chang EF
• Pure Apraxia of Speech After Resection Based in the Posterior Middle Frontal Gyrus.
  Neurosurgery 2020 Chang EF, Kurteff G, Andrews JP, Briggs RG, Conner AK, Battiste JD, Sughrue ME
• Comprehensive analysis of diverse low-grade neuroepithelial tumors with FGFR1 alterations reveals a distinct molecular signature of rosette-forming glioneuronal tumor.
  Acta neuropathologica communications 2020 Lucas CG, Gupta R, Doo P, Lee JC, Cadwell CR, Ramani B, Hofmann JW, Sloan EA, Kleinschmidt-DeMasters BK, Lee HS, Wood MD, Grafe M, Born D, Vogel H, Salamat S, Puccetti D, Scharnhorst D, Samuel D, …
• Transformation of a temporal speech cue to a spatial neural code in human auditory cortex.
  eLife 2020 Fox NP, Leonard M, Sjerps MJ, Chang EF
• Real-world experience with direct brain-responsive neurostimulation for focal onset seizures.
  Epilepsia 2020 Razavi B, Rao VR, Lin C, Bujarski KA, Patra SE, Burdette DE, Geller EB, Brown MM, Johnson EA, Drees C, Chang EF, Greenwood JE, Heck CN, Jobst BC, Gwinn RP, Warner NM, Halpern CH
• A Safe Transitions Pathway for post-craniotomy neurological surgery patients: high-value care that bypasses the intensive care unit.
  Journal of neurosurgery 2020 Young JS, Chan AK, Viner JA, Sankaran S, Chan AY, Imershein S, Meary-Miller A, Theodosopoulos PV, Jacques L, Aghi MK, Chang EF, Hervey-Jumper SL, Ward T, Gibson L, Ward MM, Sanftner P, Wong S, Amara D…
• Association of Maximal Extent of Resection of Contrast-Enhanced and Non-Contrast-Enhanced Tumor With Survival Within Molecular Subgroups of Patients With Newly Diagnosed Glioblastoma.
  JAMA oncology 2020 Molinaro AM, Hervey-Jumper S, Morshed RA, Young J, Han SJ, Chunduru P, Zhang Y, Phillips JJ, Shai A, Lafontaine M, Crane J, Chandra A, Flanigan P, Jahangiri A, Cioffi G, Ostrom Q, Anderson JE, Badve C…
• Machine translation of cortical activity to text with an encoder-decoder framework.
  Nature neuroscience 2020 Makin JG, Moses DA, Chang EF
• Gliomas arising in the setting of Li-Fraumeni syndrome stratify into two molecular subgroups with divergent clinicopathologic features.
  Acta neuropathologica 2020 Sloan EA, Hilz S, Gupta R, Cadwell C, Ramani B, Hofmann J, Kline CN, Banerjee A, Reddy A, Oberheim Bush NA, Chang S, Braunstein S, Chang EF, Raffel C, Gupta N, Sun PP, Kim JYH, Moes G, Alva E, Li R, …
• Interictal Epileptiform Discharges and the Quality of Human Intracranial Neurophysiology Data.
  Frontiers in human neuroscience 2020 Ammanuel SG, Kleen JK, Leonard MK, Chang EF
• HDMF: Hierarchical Data Modeling Framework for Modern Science Data Standards.
  Proceedings : ... IEEE International Conference on Big Data. IEEE International Conference on Big Data 2020 Tritt AJ, Rübel O, Dichter B, Ly R, Kang D, Chang EF, Frank LM, Bouchard K
• Toward a Speech Neuroprosthesis.
  JAMA 2020 Chang EF, Anumanchipalli GK
• Responsive neurostimulation for regional neocortical epilepsy.
  Epilepsia 2019 Ma BB, Fields MC, Knowlton RC, Chang EF, Szaflarski JP, Marcuse LV, Rao VR
• A speech envelope landmark for syllable encoding in human superior temporal gyrus.
  Science advances 2019 Oganian Y, Chang EF
• A Modular Approach to Vocal Learning: Disentangling the Diversity of a Complex Behavioral Trait.
  Neuron 2019 Wirthlin M, Chang EF, Knörnschild M, Krubitzer LA, Mello CV, Miller CT, Pfenning AR, Vernes SC, Tchernichovski O, Yartsev MM
• Deep learning as a tool for neural data analysis: Speech classification and cross-frequency coupling in human sensorimotor cortex.
  PLoS computational biology 2019 Livezey JA, Bouchard KE, Chang EF
• Inhibition of Manual Movements at Speech Arrest Sites in the Posterior Inferior Frontal Lobe.
  Neurosurgery 2019 Breshears JD, Southwell DG, Chang EF
• Dynamic network modeling and dimensionality reduction for human ECoG activity.
  Journal of neural engineering 2019 Yang Y, Sani OG, Chang EF, Shanechi MM
• Pilot Study of An Intracranial Electroencephalography Biomarker of Depressive Symptoms in Epilepsy.
  The Journal of neuropsychiatry and clinical neurosciences 2019 Scangos KW, Ahmad HS, Shafi A, Sellers KK, Dawes HE, Krystal A, Chang EF
• Real-time decoding of question-and-answer speech dialogue using human cortical activity.
  Nature communications 2019 Moses DA, Leonard MK, Makin JG, Chang EF
• A historical cohort of temporal lobe surgery for medically refractory epilepsy: a systematic review and meta-analysis to guide future nonrandomized controlled trial studies.
  Journal of neurosurgery 2019 Lee AT, Burke JF, Chunduru P, Molinaro AM, Knowlton R, Chang EF
• Immature excitatory neurons develop during adolescence in the human amygdala.
  Nature communications 2019 Sorrells SF, Paredes MF, Velmeshev D, Herranz-Pérez V, Sandoval K, Mayer S, Chang EF, Insausti R, Kriegstein AR, Rubenstein JL, Manuel Garcia-Verdugo J, Huang EJ, Alvarez-Buylla A
• The Encoding of Speech Sounds in the Superior Temporal Gyrus.
  Neuron 2019 Yi HG, Leonard MK, Chang EF
• Direct and indirect costs associated with stereotactic radiosurgery or open surgery for medial temporal lobe epilepsy: Results from the ROSE trial.
  Epilepsia 2019 Langfitt JT, Quigg M, Yan G, Yu W, Ward MM, Barbaro NM, Chang EF, Broshek DK, Laxer KD, Cole AJ, Sneed PK, Hess C, Tripathi M, Heck CN, Miller JW, Garcia PA, McEvoy A, Fountain NB, Salanova V, …
• Speaker-normalized sound representations in the human auditory cortex.
  Nature communications 2019 Sjerps MJ, Fox NP, Johnson K, Chang EF
• Speech synthesis from neural decoding of spoken sentences.
  Nature 2019 Anumanchipalli GK, Chartier J, Chang EF
• Biases in processing of mood-congruent facial expressions in depression.
  Psychiatry research 2019 Van Vleet T, Stark-Inbar A, Merzenich MM, Jordan JT, Wallace DL, Lee MB, Dawes HE, Chang EF, Nahum M
• Does Adult Neurogenesis Persist in the Human Hippocampus?
  Cell stem cell 2018 Paredes MF, Sorrells SF, Cebrian-Silla A, Sandoval K, Qi D, Kelley KW, James D, Mayer S, Chang J, Auguste KI, Chang EF, Gutierrez Martin AJ, Kriegstein AR, Mathern GW, Oldham MC, Huang EJ, Garcia-…
• Critical Language Areas Show Increased Functional Connectivity in Human Cortex.
  Cerebral cortex (New York, N.Y. : 1991) 2018 Rolston JD, Chang EF
• Neural Encoding of Auditory Features during Music Perception and Imagery.
  Cerebral cortex (New York, N.Y. : 1991) 2018 Martin S, Mikutta C, Leonard MK, Hungate D, Koelsch S, Shamma S, Chang EF, Millán JDR, Knight RT, Pasley BN
• Reductions in brain pericytes are associated with arteriovenous malformation vascular instability.
  Journal of neurosurgery 2018 Winkler EA, Birk H, Burkhardt JK, Chen X, Yue JK, Guo D, Rutledge WC, Lasker GF, Partow C, Tihan T, Chang EF, Su H, Kim H, Walcott BP, Lawton MT
• Direct Electrical Stimulation of Lateral Orbitofrontal Cortex Acutely Improves Mood in Individuals with Symptoms of Depression.
  Current biology : CB 2018 Rao VR, Sellers KK, Wallace DL, Lee MB, Bijanzadeh M, Sani OG, Yang Y, Shanechi MM, Dawes HE, Chang EF
• An Amygdala-Hippocampus Subnetwork that Encodes Variation in Human Mood.
  Cell 2018 Kirkby LA, Luongo FJ, Lee MB, Nahum M, Van Vleet TM, Rao VR, Dawes HE, Chang EF, Sohal VS
• Visual field defects after radiosurgery versus temporal lobectomy for mesial temporal lobe epilepsy: Findings of the ROSE trial.
  Seizure 2018 Quigg M, Barbaro NM, Ward MM, Chang EF, Broshek DK, Langfitt JT, Yan G, Laxer KD, Cole AJ, Sneed PK, Hess CP, Yu W, Newman SA, Mueller S, Tripathi M, Heck CN, Miller JW, Garcia PA, McEvoy A, Fountain …
• Subcellular organization of UBE3A in human cerebral cortex.
  Molecular autism 2018 Burette AC, Judson MC, Li AN, Chang EF, Seeley WW, Philpot BD, Weinberg RJ
• Long-term pain outcomes for recurrent idiopathic trigeminal neuralgia after stereotactic radiosurgery: a prospective comparison of first-time microvascular decompression and repeat stereotactic radiosurgery.
  Journal of neurosurgery 2018 Raygor KP, Wang DD, Ward MM, Barbaro NM, Chang EF
• Seizure Outcome After Surgical Resection of Insular Glioma.
  Neurosurgery 2018 Wang DD, Deng H, Hervey-Jumper SL, Molinaro AA, Chang EF, Berger MS
• Unsupervised Learning of Spatiotemporal Interictal Discharges in Focal Epilepsy.
  Neurosurgery 2018 Baud MO, Kleen JK, Anumanchipalli GK, Hamilton LS, Tan YL, Knowlton R, Chang EF
• Spontaneous Neural Activity in the Superior Temporal Gyrus Recapitulates Tuning for Speech Features.
  Frontiers in human neuroscience 2018 Breshears JD, Hamilton LS, Chang EF
• Encoding of Multiple Reward-Related Computations in Transient and Sustained High-Frequency Activity in Human OFC.
  Current biology : CB 2018 Saez I, Lin J, Stolk A, Chang E, Parvizi J, Schalk G, Knight RT, Hsu M
• Mood variations decoded from multi-site intracranial human brain activity.
  Nature biotechnology 2018 Sani OG, Yang Y, Lee MB, Dawes HE, Chang EF, Shanechi MM
• The Psychiatric Cell Map Initiative: A Convergent Systems Biological Approach to Illuminating Key Molecular Pathways in Neuropsychiatric Disorders.
  Cell 2018 Willsey AJ, Morris MT, Wang S, Willsey HR, Sun N, Teerikorpi N, Baum TB, Cagney G, Bender KJ, Desai TA, Srivastava D, Davis GW, Doudna J, Chang E, Sohal V, Lowenstein DH, Li H, Agard D, Keiser MJ, …
• A valid alternative for in-person language assessments in brain tumor patients: feasibility and validity measures of the new TeleLanguage test.
  Neuro-oncology practice 2018 De Witte E, Piai V, Kurteff G, Cai R, Mariën P, Dronkers N, Chang E, Berger M
• Neurosurgical Patients as Human Research Subjects: Ethical Considerations in Intracranial Electrophysiology Research.
  Neurosurgery 2018 Chiong W, Leonard MK, Chang EF
• The Control of Vocal Pitch in Human Laryngeal Motor Cortex.
  Cell 2018 Dichter BK, Breshears JD, Leonard MK, Chang EF
• Low-frequency cortical activity is a neuromodulatory target that tracks recovery after stroke.
  Nature medicine 2018 Ramanathan DS, Guo L, Gulati T, Davidson G, Hishinuma AK, Won SJ, Knight RT, Chang EF, Swanson RA, Ganguly K
• The genetic landscape of ganglioglioma.
  Acta neuropathologica communications 2018 Pekmezci M, Villanueva-Meyer JE, Goode B, Van Ziffle J, Onodera C, Grenert JP, Bastian BC, Chamyan G, Maher OM, Khatib Z, Kleinschmidt-DeMasters BK, Samuel D, Mueller S, Banerjee A, Clarke JL, Cooney …
• Safety and outcomes of resection of butterfly glioblastoma.
  Neurosurgical focus 2018 Dayani F, Young JS, Bonte A, Chang EF, Theodosopoulos P, McDermott MW, Berger MS, Aghi MK
• A Spatial Map of Onset and Sustained Responses to Speech in the Human Superior Temporal Gyrus.
  Current biology : CB 2018 Hamilton LS, Edwards E, Chang EF
• Direct cortical stimulation of inferior frontal cortex disrupts both speech and music production in highly trained musicians.
  Cognitive neuropsychology 2018 Leonard MK, Desai M, Hungate D, Cai R, Singhal NS, Knowlton RC, Chang EF
• Encoding of Articulatory Kinematic Trajectories in Human Speech Sensorimotor Cortex.
  Neuron 2018 Chartier J, Anumanchipalli GK, Johnson K, Chang EF
• Multiple Subpial Transections for Medically Refractory Epilepsy: A Disaggregated Review of Patient-Level Data.
  Neurosurgery 2018 Rolston JD, Deng H, Wang DD, Englot DJ, Chang EF
• Seizure localization by chronic ambulatory electrocorticography.
  Clinical neurophysiology practice 2018 Chan AY, Knowlton RC, Chang EF, Rao VR
• Direct electrical stimulation of human cortex evokes high gamma activity that predicts conscious somatosensory perception.
  Journal of neural engineering 2018 Muller L, Rolston JD, Fox NP, Knowlton R, Rao VR, Chang EF
• Radiosurgery versus open surgery for mesial temporal lobe epilepsy: The randomized, controlled ROSE trial.
  Epilepsia 2018 Barbaro NM, Quigg M, Ward MM, Chang EF, Broshek DK, Langfitt JT, Yan G, Laxer KD, Cole AJ, Sneed PK, Hess CP, Yu W, Tripathi M, Heck CN, Miller JW, Garcia PA, McEvoy A, Fountain NB, Salanova V, …
• Closed-Loop Deep Brain Stimulation for Refractory Chronic Pain.
  Frontiers in computational neuroscience 2018 Shirvalkar P, Veuthey TL, Dawes HE, Chang EF
• Responsive neurostimulation for treatment of pediatric drug-resistant epilepsy.
  Epilepsy & behavior case reports 2018 Singhal NS, Numis AL, Lee MB, Chang EF, Sullivan JE, Auguste KI, Rao VR
• Radiation-induced Cavernous Malformation as a Late Sequelae of Stereotactic Radiosurgery for Epilepsy.
  Cureus 2018 Winkler EA, Rutledge C, Ward M, Tihan T, Sneed PK, Barbaro N, Garcia P, McDermott M, Chang EF
• Human hippocampal neurogenesis drops sharply in children to undetectable levels in adults.
  Nature 2018 Sorrells SF, Paredes MF, Cebrian-Silla A, Sandoval K, Qi D, Kelley KW, James D, Mayer S, Chang J, Auguste KI, Chang EF, Gutierrez AJ, Kriegstein AR, Mathern GW, Oldham MC, Huang EJ, Garcia-Verdugo JM,…
• Mirroring in the Human Brain: Deciphering the Spatial-Temporal Patterns of the Human Mirror Neuron System.
  Cerebral cortex (New York, N.Y. : 1991) 2018 Perry A, Stiso J, Chang EF, Lin JJ, Parvizi J, Knight RT
• Effect of neurostimulation on cognition and mood in refractory epilepsy.
  Epilepsia open 2018 Chan AY, Rolston JD, Rao VR, Chang EF
• Human Sensorimotor Cortex Control of Directly Measured Vocal Tract Movements during Vowel Production.
  The Journal of neuroscience : the official journal of the Society for Neuroscience 2018 Conant DF, Bouchard KE, Leonard MK, Chang EF
• Neural correlates of sine-wave speech intelligibility in human frontal and temporal cortex.
  Brain and language 2018 Khoshkhoo S, Leonard MK, Mesgarani N, Chang EF
• Real-time classification of auditory sentences using evoked cortical activity in humans.
  Journal of neural engineering 2018 Moses DA, Leonard MK, Chang EF
• Multi-day rhythms modulate seizure risk in epilepsy.
  Nature communications 2018 Baud MO, Kleen JK, Mirro EA, Andrechak JC, King-Stephens D, Chang EF, Rao VR
• Tumor Evolution of Glioma-Intrinsic Gene Expression Subtypes Associates with Immunological Changes in the Microenvironment.
  Cancer cell 2018 Wang Q, Hu B, Hu X, Kim H, Squatrito M, Scarpace L, deCarvalho AC, Lyu S, Li P, Li Y, Barthel F, Cho HJ, Lin YH, Satani N, Martinez-Ledesma E, Zheng S, Chang E, Gabriel Sauvé CE, Olar A, Lan ZD, …
• Persistent neuronal activity in human prefrontal cortex links perception and action.
  Nature human behaviour 2017 Haller M, Case J, Crone NE, Chang EF, King-Stephens D, Laxer KD, Weber PB, Parvizi J, Knight RT, Shestyuk AY
• Selective Interference with Syntactic Encoding during Sentence Production by Direct Electrocortical Stimulation of the Inferior Frontal Gyrus.
  Journal of cognitive neuroscience 2017 Chang EF, Kurteff G, Wilson SM
• Semi-automated Anatomical Labeling and Inter-subject Warping of High-Density Intracranial Recording Electrodes in Electrocorticography.
  Frontiers in neuroinformatics 2017 Hamilton LS, Chang DL, Lee MB, Chang EF
• Psychogenic nonepileptic seizures in patients with surgically treated temporal lobe epilepsy: Presurgical and de novo postsurgical occurrence.
  Epilepsy & behavior : E&B 2017 González Otárula KA, Tan YL, Dubeau F, Correa JA, Chang E, Hall JA, Knowlton RC, Kobayashi E
• Intonational speech prosody encoding in the human auditory cortex.
  Science (New York, N.Y.) 2017 Tang C, Hamilton LS, Chang EF
• Tumor Evolution of Glioma-Intrinsic Gene Expression Subtypes Associates with Immunological Changes in the Microenvironment.
  Cancer cell 2017 Wang Q, Hu B, Hu X, Kim H, Squatrito M, Scarpace L, deCarvalho AC, Lyu S, Li P, Li Y, Barthel F, Cho HJ, Lin YH, Satani N, Martinez-Ledesma E, Zheng S, Chang E, Sauvé CG, Olar A, Lan ZD, Finocchiaro G…
• Sparse coding of ECoG signals identifies interpretable components for speech control in human sensorimotor cortex.
  Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference 2017 Bouchard KE, Bujan AF, Chang EF, Sommer FT
• Multi-scale visual analysis of time-varying electrocorticography data via clustering of brain regions.
  BMC bioinformatics 2017 Murugesan S, Bouchard K, Chang E, Dougherty M, Hamann B, Weber GH
• Immediate Mood Scaler: Tracking Symptoms of Depression and Anxiety Using a Novel Mobile Mood Scale.
  JMIR mHealth and uHealth 2017 Nahum M, Van Vleet TM, Sohal VS, Mirzabekov JJ, Rao VR, Wallace DL, Lee MB, Dawes H, Stark-Inbar A, Jordan JT, Biagianti B, Merzenich M, Chang EF
• Chronic ambulatory electrocorticography from human speech cortex.
  NeuroImage 2017 Rao VR, Leonard MK, Kleen JK, Lucas BA, Mirro EA, Chang EF
• Prospective comparison of long-term pain relief rates after first-time microvascular decompression and stereotactic radiosurgery for trigeminal neuralgia.
  Journal of neurosurgery 2017 Wang DD, Raygor KP, Cage TA, Ward MM, Westcott S, Barbaro NM, Chang EF
• Connected speech in transient aphasias after left hemisphere resective surgery.
  Aphasiology 2017 McCarron A, Chavez A, Babiak M, Berger MS, Chang EF, Wilson SM
• Indications and Efficacy of Gamma Knife Stereotactic Radiosurgery for Recurrent Glioblastoma: 2 Decades of Institutional Experience.
  Neurosurgery 2017 Imber BS, Kanungo I, Braunstein S, Barani IJ, Fogh SE, Nakamura JL, Berger MS, Chang EF, Molinaro AM, Cabrera JR, McDermott MW, Sneed PK, Aghi MK
• Perceptual restoration of masked speech in human cortex.
  Nature communications 2016 Leonard MK, Baud MO, Sjerps MJ, Chang EF
• Systemic inaccuracies in the National Surgical Quality Improvement Program database: Implications for accuracy and validity for neurosurgery outcomes research.
  Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 2016 Rolston JD, Han SJ, Chang EF
• New Developments in Understanding the Complexity of Human Speech Production.
  The Journal of neuroscience : the official journal of the Society for Neuroscience 2016 Simonyan K, Ackermann H, Chang EF, Greenlee JD
• Methods for Specifying Scientific Data Standards and Modeling Relationships with Applications to Neuroscience.
  Frontiers in neuroinformatics 2016 Rübel O, Dougherty M, Denes P, Conant D, Chang EF, Bouchard K
• Muscle synergies after stroke are correlated with perilesional high gamma.
  Annals of clinical and translational neurology 2016 Godlove J, Gulati T, Dichter B, Chang E, Ganguly K
• Immunogenomics of Hypermutated Glioblastoma: A Patient with Germline POLE Deficiency Treated with Checkpoint Blockade Immunotherapy.
  Cancer discovery 2016 Johanns TM, Miller CA, Dorward IG, Tsien C, Chang E, Perry A, Uppaluri R, Ferguson C, Schmidt RE, Dahiya S, Ansstas G, Mardis ER, Dunn GP
• Rates and Predictors of Seizure Freedom With Vagus Nerve Stimulation for Intractable Epilepsy.
  Neurosurgery 2016 Englot DJ, Rolston JD, Wright CW, Hassnain KH, Chang EF
• Spatial resolution dependence on spectral frequency in human speech cortex electrocorticography.
  Journal of neural engineering 2016 Muller L, Hamilton LS, Edwards E, Bouchard KE, Chang EF
• Neural speech recognition: continuous phoneme decoding using spatiotemporal representations of human cortical activity.
  Journal of neural engineering 2016 Moses DA, Mesgarani N, Leonard MK, Chang EF
• Decoding speech using the timing of neural signal modulation.
  Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference 2016 Jiang W, Pailla T, Dichter B, Chang EF, Gilja V
• ECoG data analyses to inform closed-loop BCI experiments for speech-based prosthetic applications.
  Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference 2016 Pailla T, Jiang W, Dichter B, Chang EF, Gilja V
• Thin-film, high-density micro-electrocorticographic decoding of a human cortical gyrus.
  Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference 2016 Muller L, Felix S, Shah KG, Pannu S, Chang EF
• The peri-Sylvian cortical network underlying single word repetition revealed by electrocortical stimulation and direct neural recordings.
  Brain and language 2016 Leonard MK, Cai R, Babiak MC, Ren A, Chang EF
• Dynamic Structure of Neural Variability in the Cortical Representation of Speech Sounds.
  The Journal of neuroscience : the official journal of the Society for Neuroscience 2016 Dichter BK, Bouchard KE, Chang EF
• Seizure outcomes in nonresective epilepsy surgery: an update.
  Neurosurgical review 2016 Englot DJ, Birk H, Chang EF
• Rate and complications of adult epilepsy surgery in North America: Analysis of multiple databases.
  Epilepsy research 2016 Rolston JD, Englot DJ, Knowlton RC, Chang EF
• Correction: The auditory representation of speech sounds in human motor cortex.
  eLife 2016 Cheung C, Hamilton LS, Johnson K, Chang EF
• High-Resolution, Non-Invasive Imaging of Upper Vocal Tract Articulators Compatible with Human Brain Recordings.
  PloS one 2016 Bouchard KE, Conant DF, Anumanchipalli GK, Dichter B, Chaisanguanthum KS, Johnson K, Chang EF
• The auditory representation of speech sounds in human motor cortex.
  eLife 2016 Cheung C, Hamiton LS, Johnson K, Chang EF
• Stereotactic probability and variability of speech arrest and anomia sites during stimulation mapping of the language dominant hemisphere.
  Journal of neurosurgery 2016 Chang EF, Breshears JD, Raygor KP, Lau D, Molinaro AM, Berger MS
• Frontal and motor cortex contributions to response inhibition: evidence from electrocorticography.
  Journal of neurophysiology 2016 Fonken YM, Rieger JW, Tzvi E, Crone NE, Chang E, Parvizi J, Knight RT, Krämer UM
• Human Superior Temporal Gyrus Organization of Spectrotemporal Modulation Tuning Derived from Speech Stimuli.
  The Journal of neuroscience : the official journal of the Society for Neuroscience 2016 Hullett PW, Hamilton LS, Mesgarani N, Schreiner CE, Chang EF
• Major and minor complications in extraoperative electrocorticography: A review of a national database.
  Epilepsy research 2016 Rolston JD, Englot DJ, Cornes S, Chang EF
• The sensitivity and significance of lateralized interictal slow activity on magnetoencephalography in focal epilepsy.
  Epilepsy research 2016 Englot DJ, Nagarajan SS, Wang DD, Rolston JD, Mizuiri D, Honma SM, Mantle M, Tarapore PE, Knowlton RC, Chang EF, Kirsch HE
• Epilepsy and brain tumors.
  Handbook of clinical neurology 2016 Englot DJ, Chang EF, Vecht CJ
• Minimally Invasive Epilepsy Surgery.
  Neurosurgery clinics of North America 2016 Zaghloul KA, Chang EF
• Epilepsy with temporal encephalocele: Characteristics of electrocorticography and surgical outcome.
  Epilepsia 2015 Panov F, Li Y, Chang EF, Knowlton R, Cornes SB
• Purification and Characterization of Progenitor and Mature Human Astrocytes Reveals Transcriptional and Functional Differences with Mouse.
  Neuron 2015 Zhang Y, Sloan SA, Clarke LE, Caneda C, Plaza CA, Blumenthal PD, Vogel H, Steinberg GK, Edwards MS, Li G, Duncan JA, Cheshier SH, Shuer LM, Chang EF, Grant GA, Gephart MG, Barres BA
• Surgical management of medically refractory epilepsy in patients with polymicrogyria.
  Epilepsia 2015 Wang DD, Knox R, Rolston JD, Englot DJ, Barkovich AJ, Tihan T, Auguste KI, Knowlton RC, Cornes SB, Chang EF
• Seizures in supratentorial meningioma: a systematic review and meta-analysis.
  Journal of neurosurgery 2015 Englot DJ, Magill ST, Han SJ, Chang EF, Berger MS, McDermott MW
• Stereotactic Laser Ablation for Hypothalamic Hamartoma.
  Neurosurgery clinics of North America 2015 Rolston JD, Chang EF
• Awake brain tumor resection during pregnancy: Decision making and technical nuances.
  Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 2015 Meng L, Han SJ, Rollins MD, Gelb AW, Chang EF
• Two cases of rheumatoid meningitis.
  Neuropathology : official journal of the Japanese Society of Neuropathology 2015 Magaki S, Chang E, Hammond RR, Yang I, Mackenzie IR, Chou BT, Choi SI, Jen JC, Pope WB, Bell DA, Vinters HV
• Strategies for optical control and simultaneous electrical readout of extended cortical circuits.
  Journal of neuroscience methods 2015 Ledochowitsch P, Yazdan-Shahmorad A, Bouchard KE, Diaz-Botia C, Hanson TL, He JW, Seybold BA, Olivero E, Phillips EA, Blanche TJ, Schreiner CE, Hasenstaub A, Chang EF, Sabes PN, Maharbiz MM
• Corpus callosotomy versus vagus nerve stimulation for atonic seizures and drop attacks: A systematic review.
  Epilepsy & behavior : E&B 2015 Rolston JD, Englot DJ, Wang DD, Garcia PA, Chang EF
• Oscillatory dynamics coordinating human frontal networks in support of goal maintenance.
  Nature neuroscience 2015 Voytek B, Kayser AS, Badre D, Fegen D, Chang EF, Crone NE, Parvizi J, Knight RT, D'Esposito M
• Transient aphasias after left hemisphere resective surgery.
  Journal of neurosurgery 2015 Wilson SM, Lam D, Babiak MC, Perry DW, Shih T, Hess CP, Berger MS, Chang EF
• The influence of lexical statistics on temporal lobe cortical dynamics during spoken word listening.
  Brain and language 2015 Cibelli ES, Leonard MK, Johnson K, Chang EF
• Minimally invasive surgical approaches for temporal lobe epilepsy.
  Epilepsy & behavior : E&B 2015 Chang EF, Englot DJ, Vadera S
• Global and regional functional connectivity maps of neural oscillations in focal epilepsy.
  Brain : a journal of neurology 2015 Englot DJ, Hinkley LB, Kort NS, Imber BS, Mizuiri D, Honma SM, Findlay AM, Garrett C, Cheung PL, Mantle M, Tarapore PE, Knowlton RC, Chang EF, Kirsch HE, Nagarajan SS
• A probabilistic map of the human ventral sensorimotor cortex using electrical stimulation.
  Journal of neurosurgery 2015 Breshears JD, Molinaro AM, Chang EF
• The cortical computations underlying feedback control in vocal production.
  Current opinion in neurobiology 2015 Houde JF, Chang EF
• Dynamic encoding of speech sequence probability in human temporal cortex.
  The Journal of neuroscience : the official journal of the Society for Neuroscience 2015 Leonard MK, Bouchard KE, Tang C, Chang EF
• Epileptogenic zone localization using magnetoencephalography predicts seizure freedom in epilepsy surgery.
  Epilepsia 2015 Englot DJ, Nagarajan SS, Imber BS, Raygor KP, Honma SM, Mizuiri D, Mantle M, Knowlton RC, Kirsch HE, Chang EF
• Towards large-scale, human-based, mesoscopic neurotechnologies.
  Neuron 2015 Chang EF
• Awake craniotomy in a patient with ejection fraction of 10%: considerations of cerebrovascular and cardiovascular physiology.
  Journal of clinical anesthesia 2015 Meng L, Weston SD, Chang EF, Gelb AW
• National trends and complication rates for invasive extraoperative electrocorticography in the USA.
  Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 2015 Rolston JD, Ouyang D, Englot DJ, Wang DD, Chang EF
• The results of a third Gamma Knife procedure for recurrent trigeminal neuralgia.
  Journal of neurosurgery 2015 Tempel ZJ, Chivukula S, Monaco EA, Bowden G, Kano H, Niranjan A, Chang EF, Sneed PK, Kaufmann AM, Sheehan J, Mathieu D, Lunsford LD
• A predictive algorithm for evaluating elevated serum prolactin in patients with a sellar mass.
  Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 2014 Cheng JS, Salinas R, Molinaro A, Chang EF, Kunwar S, Blevins L, Aghi MK
• Factors associated with failed focal neocortical epilepsy surgery.
  Neurosurgery 2014 Englot DJ, Raygor KP, Molinaro AM, Garcia PA, Knowlton RC, Auguste KI, Chang EF
• Contemporary model of language organization: an overview for neurosurgeons.
  Journal of neurosurgery 2014 Chang EF, Raygor KP, Berger MS
• Unilateral holohemispheric central nervous system lesions associated with medically refractory epilepsy in the pediatric population: a retrospective series of hemimegalencephaly and Rasmussen's encephalitis.
  Journal of neurosurgery. Pediatrics 2014 Wang DD, Benkli B, Auguste KI, Garcia PA, Sullivan J, Barkovich AJ, Chang EF, Tihan T
• Control of spoken vowel acoustics and the influence of phonetic context in human speech sensorimotor cortex.
  The Journal of neuroscience : the official journal of the Society for Neuroscience 2014 Bouchard KE, Chang EF
• Epilepsy surgery failure in children: a quantitative and qualitative analysis.
  Journal of neurosurgery. Pediatrics 2014 Englot DJ, Han SJ, Rolston JD, Ivan ME, Kuperman RA, Chang EF, Gupta N, Sullivan JE, Auguste KI
• Isolated intracerebral light chain deposition disease: novel imaging and pathologic findings.
  Clinical imaging 2014 Yu JP, Wilson DM, Chang EF, Cotter J, Perry A, Mahindra A, Glastonbury CM
• Dynamic speech representations in the human temporal lobe.
  Trends in cognitive sciences 2014 Leonard MK, Chang EF
• A review of percutaneous treatments for trigeminal neuralgia.
  Neurosurgery 2014 Cheng JS, Lim DA, Chang EF, Barbaro NM
• Oscillatory dynamics track motor performance improvement in human cortex.
  PloS one 2014 Dürschmid S, Quandt F, Krämer UM, Hinrichs H, Heinze HJ, Schulz R, Pannek H, Chang EF, Knight RT
• Rates and predictors of seizure freedom in resective epilepsy surgery: an update.
  Neurosurgical review 2014 Englot DJ, Chang EF
• Phonetic feature encoding in human superior temporal gyrus.
  Science (New York, N.Y.) 2014 Mesgarani N, Cheung C, Johnson K, Chang EF
• Neural decoding of spoken vowels from human sensory-motor cortex with high-density electrocorticography.
  Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference 2014 Bouchard KE, Chang EF
• Seizure types and frequency in patients who "fail" temporal lobectomy for intractable epilepsy.
  Neurosurgery 2013 Englot DJ, Lee AT, Tsai C, Halabi C, Barbaro NM, Auguste KI, Garcia PA, Chang EF
• Safety and efficacy of motor mapping utilizing short pulse train direct cortical stimulation.
  Stereotactic and functional neurosurgery 2013 Tate MC, Guo L, McEvoy J, Chang EF
• A Review of Percutaneous Treatments for Trigeminal Neuralgia.
  Neurosurgery 2013 Cheng JS, Lim DA, Chang EF, Barbaro NM
• Hidden Markov model and support vector machine based decoding of finger movements using electrocorticography.
  Journal of neural engineering 2013 Wissel T, Pfeiffer T, Frysch R, Knight RT, Chang EF, Hinrichs H, Rieger JW, Rose G
• Speech map in the human ventral sensory-motor cortex.
  Current opinion in neurobiology 2013 Conant D, Bouchard KE, Chang EF
• Syllabic (∼2-5 Hz) and fluctuation (∼1-10 Hz) ranges in speech and auditory processing.
  Hearing research 2013 Edwards E, Chang EF
• Trends in surgical treatment for trigeminal neuralgia in the United States of America from 1988 to 2008.
  Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 2013 Wang DD, Ouyang D, Englot DJ, Rolston JD, Molinaro AM, Ward M, Chang EF
• A comprehensive long-term retrospective analysis of silent corticotrophic adenomas vs hormone-negative adenomas.
  Neurosurgery 2013 Jahangiri A, Wagner JR, Pekmezci M, Hiniker A, Chang EF, Kunwar S, Blevins L, Aghi MK
• Seizure outcomes after resective surgery for extra-temporal lobe epilepsy in pediatric patients.
  Journal of neurosurgery. Pediatrics 2013 Englot DJ, Breshears JD, Sun PP, Chang EF, Auguste KI
• Seizure outcomes after temporal lobectomy in pediatric patients.
  Journal of neurosurgery. Pediatrics 2013 Englot DJ, Rolston JD, Wang DD, Sun PP, Chang EF, Auguste KI
• Emergent categorical representation of natural, complex sounds resulting from the early post-natal sound environment.
  Neuroscience 2013 Bao S, Chang EF, Teng CL, Heiser MA, Merzenich MM
• Effects of temporal lobectomy on consciousness-impairing and consciousness-sparing seizures in children.
  Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery 2013 Englot DJ, Rutkowski MJ, Ivan ME, Sun PP, Kuperman RA, Chang EF, Gupta N, Sullivan JE, Auguste KI
• Visual field defects after radiosurgery for mesial temporal lobe epilepsy.
  Epilepsia 2013 Hensley-Judge H, Quigg M, Barbaro NM, Newman SA, Ward MM, Chang EF, Broshek DK, Lamborn KR, Laxer KD, Garcia P, Heck CN, Kondziolka D, Beach R, Salanova V, Goodman R
• Neurosurgery and the dawning age of Brain-Machine Interfaces.
  Surgical neurology international 2013 Rowland NC, Breshears J, Chang EF
• Functional organization of human sensorimotor cortex for speech articulation.
  Nature 2013 Bouchard KE, Mesgarani N, Johnson K, Chang EF
• Human cortical sensorimotor network underlying feedback control of vocal pitch.
  Proceedings of the National Academy of Sciences of the United States of America 2013 Chang EF, Niziolek CA, Knight RT, Nagarajan SS, Houde JF
• Transmantle sign in focal cortical dysplasia: a unique radiological entity with excellent prognosis for seizure control.
  Journal of neurosurgery 2012 Wang DD, Deans AE, Barkovich AJ, Tihan T, Barbaro NM, Garcia PA, Chang EF
• Proceedings of the Third International Workshop on Advances in Electrocorticography.
  Epilepsy & behavior : E&B 2012 Ritaccio A, Beauchamp M, Bosman C, Brunner P, Chang E, Crone N, Gunduz A, Gupta D, Knight R, Leuthardt E, Litt B, Moran D, Ojemann J, Parvizi J, Ramsey N, Rieger J, Viventi J, Voytek B, Williams J, …
• Relationship between hospital surgical volume, lobectomy rates, and adverse perioperative events at US epilepsy centers.
  Journal of neurosurgery 2012 Englot DJ, Ouyang D, Wang DD, Rolston JD, Garcia PA, Chang EF
• Efficacy of vagus nerve stimulation in posttraumatic versus nontraumatic epilepsy.
  Journal of neurosurgery 2012 Englot DJ, Rolston JD, Wang DD, Hassnain KH, Gordon CM, Chang EF
• Seizure predictors and control after microsurgical resection of supratentorial arteriovenous malformations in 440 patients.
  Neurosurgery 2012 Englot DJ, Young WL, Han SJ, McCulloch CE, Chang EF, Lawton MT
• Real-time, time-frequency mapping of event-related cortical activation.
  Journal of neural engineering 2012 Cheung C, Chang EF
• Long-term seizure control outcomes after resection of gangliogliomas.
  Neurosurgery 2012 Southwell DG, Garcia PA, Berger MS, Barbaro NM, Chang EF
• Acute effects of thalamic deep brain stimulation and thalamotomy on sensorimotor cortex local field potentials in essential tremor.
  Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology 2012 Air EL, Ryapolova-Webb E, de Hemptinne C, Ostrem JL, Galifianakis NB, Larson PS, Chang EF, Starr PA
• Selective cortical representation of attended speaker in multi-talker speech perception.
  Nature 2012 Mesgarani N, Chang EF
• Characteristics and treatment of seizures in patients with high-grade glioma: a review.
  Neurosurgery clinics of North America 2012 Englot DJ, Berger MS, Chang EF, Garcia PA
• Extent of surgical resection predicts seizure freedom in low-grade temporal lobe brain tumors.
  Neurosurgery 2012 Englot DJ, Han SJ, Berger MS, Barbaro NM, Chang EF
• Transsylvian-transinsular approaches to the insula and basal ganglia: operative techniques and results with vascular lesions.
  Neurosurgery 2012 Potts MB, Chang EF, Young WL, Lawton MT, UCSF Brain AVM Study Project
• Epilepsy surgery trends in the United States, 1990-2008.
  Neurology 2012 Englot DJ, Ouyang D, Garcia PA, Barbaro NM, Chang EF
• Comparison of seizure control outcomes and the safety of vagus nerve, thalamic deep brain, and responsive neurostimulation: evidence from randomized controlled trials.
  Neurosurgical focus 2012 Rolston JD, Englot DJ, Wang DD, Shih T, Chang EF
• A meta-analysis of predictors of seizure freedom in the surgical management of focal cortical dysplasia.
  Journal of neurosurgery 2012 Rowland NC, Englot DJ, Cage TA, Sughrue ME, Barbaro NM, Chang EF
• Rates and predictors of long-term seizure freedom after frontal lobe epilepsy surgery: a systematic review and meta-analysis.
  Journal of neurosurgery 2012 Englot DJ, Wang DD, Rolston JD, Shih TT, Chang EF
• Reconstructing speech from human auditory cortex.
  PLoS biology 2012 Pasley BN, David SV, Mesgarani N, Flinker A, Shamma SA, Crone NE, Knight RT, Chang EF
• Efficacy of vagus nerve stimulation for epilepsy by patient age, epilepsy duration, and seizure type.
  Neurosurgery clinics of North America 2011 Englot DJ, Chang EF, Auguste KI
• Epilepsy surgery: the emerging field of neuromodulation.
  Neurosurgery clinics of North America 2011 Chang EF, Barbaro NM
• Factors associated with seizure freedom in the surgical resection of glioneuronal tumors.
  Epilepsia 2011 Englot DJ, Berger MS, Barbaro NM, Chang EF
• Excess mortality for patients with residual disease following resection of pituitary adenomas.
  Pituitary 2011 Sughrue ME, Chang EF, Gabriel RA, Aghi MK, Blevins LS
• Vagus nerve stimulation for epilepsy: a meta-analysis of efficacy and predictors of response.
  Journal of neurosurgery 2011 Englot DJ, Chang EF, Auguste KI
• Predictors of seizure freedom in the surgical treatment of supratentorial cavernous malformations.
  Journal of neurosurgery 2011 Englot DJ, Han SJ, Lawton MT, Chang EF
• Predictors of seizure freedom after surgery for malformations of cortical development.
  Annals of neurology 2011 Chang EF, Wang DD, Barkovich AJ, Tihan T, Auguste KI, Sullivan JE, Garcia PA, Barbaro NM
• Predictors of seizure freedom after resection of supratentorial low-grade gliomas. A review.
  Journal of neurosurgery 2011 Englot DJ, Berger MS, Barbaro NM, Chang EF
• Lead cap localization using ultrasound in deep brain stimulation surgery: technical note.
  Minimally invasive neurosurgery : MIN 2011 Englot DJ, Chang EF, Larson PS
• Incidence and management of venous air embolisms during awake deep brain stimulation surgery in a large clinical series.
  Stereotactic and functional neurosurgery 2011 Chang EF, Cheng JS, Richardson RM, Lee C, Starr PA, Larson PS
• Homotopic organization of essential language sites in right and bilateral cerebral hemispheric dominance.
  Journal of neurosurgery 2011 Chang EF, Wang DD, Perry DW, Barbaro NM, Berger MS
• Perinatal asphyxia affects rat auditory processing: implications for auditory perceptual impairments in neurodevelopmental disorders.
  PloS one 2010 Strata F, Stoianov IP, de Villers-Sidani E, Bonham B, Martone T, Kenet T, Chang EF, Vincenti V, Merzenich MM
• Single-trial speech suppression of auditory cortex activity in humans.
  The Journal of neuroscience : the official journal of the Society for Neuroscience 2010 Flinker A, Chang EF, Kirsch HE, Barbaro NM, Crone NE, Knight RT
• Early surgical intervention in adult patients with ganglioglioma is associated with improved clinical seizure outcomes.
  Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 2010 Yang I, Chang EF, Han SJ, Barry JJ, Fang S, Tihan T, Barbaro NM, Parsa AT
• Sub-centimeter language organization in the human temporal lobe.
  Brain and language 2010 Flinker A, Chang EF, Barbaro NM, Berger MS, Knight RT
• Assessment of morbidity following resection of cingulate gyrus gliomas. Clinical article.
  Journal of neurosurgery 2010 Tate MC, Kim CY, Chang EF, Polley MY, Berger MS
• Categorical speech representation in human superior temporal gyrus.
  Nature neuroscience 2010 Chang EF, Rieger JW, Johnson K, Berger MS, Barbaro NM, Knight RT
• Long term outcome following repeat transsphenoidal surgery for recurrent endocrine-inactive pituitary adenomas.
  Pituitary 2010 Chang EF, Sughrue ME, Zada G, Wilson CB, Blevins LS, Kunwar S
• Functional mapping-guided resection of low-grade gliomas in eloquent areas of the brain: improvement of long-term survival. Clinical article.
  Journal of neurosurgery 2010 Chang EF, Clark A, Smith JS, Polley MY, Chang SM, Barbaro NM, Parsa AT, McDermott MW, Berger MS
• Supratentorial cavernous malformations in eloquent and deep locations: surgical approaches and outcomes. Clinical article.
  Journal of neurosurgery 2010 Chang EF, Gabriel RA, Potts MB, Berger MS, Lawton MT
• Postoperative seizures following the resection of convexity meningiomas: are prophylactic anticonvulsants indicated? Clinical article.
  Journal of neurosurgery 2010 Sughrue ME, Rutkowski MJ, Chang EF, Shangari G, Kane AJ, McDermott MW, Berger MS, Parsa AT
• Long-term benefit sustained after bilateral pallidal deep brain stimulation in patients with refractory tardive dystonia.
  Stereotactic and functional neurosurgery 2010 Chang EF, Schrock LE, Starr PA, Ostrem JL
• Cortical spatio-temporal dynamics underlying phonological target detection in humans.
  Journal of cognitive neuroscience 2010 Chang EF, Edwards E, Nagarajan SS, Fogelson N, Dalal SS, Canolty RT, Kirsch HE, Barbaro NM, Knight RT
• Nonresective epilepsy surgery.
  Epilepsia 2010 Chang EF, Barbaro NM
• Predictors of efficacy after stereotactic radiosurgery for medial temporal lobe epilepsy.
  Neurology 2010 Chang EF, Quigg M, Oh MC, Dillon WP, Ward MM, Laxer KD, Broshek DK, Barbaro NM, Epilepsy Radiosurgery Study Group
• Seizure control outcomes after resection of dysembryoplastic neuroepithelial tumor in 50 patients.
  Journal of neurosurgery. Pediatrics 2010 Chang EF, Christie C, Sullivan JE, Garcia PA, Tihan T, Gupta N, Berger MS, Barbaro NM
• Magnetic source imaging for the surgical evaluation of electroencephalography-confirmed secondary bilateral synchrony in intractable epilepsy.
  Journal of neurosurgery 2009 Chang EF, Nagarajan SS, Mantle M, Barbaro NM, Kirsch HE
• Cortical representation of ipsilateral arm movements in monkey and man.
  The Journal of neuroscience : the official journal of the Society for Neuroscience 2009 Ganguly K, Secundo L, Ranade G, Orsborn A, Chang EF, Dimitrov DF, Wallis JD, Barbaro NM, Knight RT, Carmena JM
• Multiinstitutional validation of the University of California at San Francisco Low-Grade Glioma Prognostic Scoring System. Clinical article.
  Journal of neurosurgery 2009 Chang EF, Clark A, Jensen RL, Bernstein M, Guha A, Carrabba G, Mukhopadhyay D, Kim W, Liau LM, Chang SM, Smith JS, Berger MS, McDermott MW
• Seizure characteristics and control after microsurgical resection of supratentorial cerebral cavernous malformations.
  Neurosurgery 2009 Chang EF, Gabriel RA, Potts MB, Garcia PA, Barbaro NM, Lawton MT
• Surgical considerations in the management of falcotentorial meningiomas: advantages of the bilateral occipital transtentorial/transfalcine craniotomy for large tumors.
  Neurosurgery 2009 Quiñones-Hinojosa A, Chang EF, Chaichana KL, McDermott MW
• Safety and feasibility of switching from phenytoin to levetiracetam monotherapy for glioma-related seizure control following craniotomy: a randomized phase II pilot study.
  Journal of neuro-oncology 2009 Lim DA, Tarapore P, Chang E, Burt M, Chakalian L, Barbaro N, Chang S, Lamborn KR, McDermott MW
• Pre-operative dopamine agonist therapy improves post-operative tumor control following prolactinoma resection.
  Pituitary 2009 Sughrue ME, Chang EF, Tyrell JB, Kunwar S, Wilson CB, Blevins LS
• Preoperative prognostic classification system for hemispheric low-grade gliomas in adults.
  Journal of neurosurgery 2008 Chang EF, Smith JS, Chang SM, Lamborn KR, Prados MD, Butowski N, Barbaro NM, Parsa AT, Berger MS, McDermott MM
• Long-term recurrence and mortality after surgery and adjuvant radiotherapy for nonfunctional pituitary adenomas.
  Journal of neurosurgery 2008 Chang EF, Zada G, Kim S, Lamborn KR, Quinones-Hinojosa A, Tyrrell JB, Wilson CB, Kunwar S
• Role of extent of resection in the long-term outcome of low-grade hemispheric gliomas.
  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2008 Smith JS, Chang EF, Lamborn KR, Chang SM, Prados MD, Cha S, Tihan T, Vandenberg S, McDermott MW, Berger MS
• Seizure characteristics and control following resection in 332 patients with low-grade gliomas.
  Journal of neurosurgery 2008 Chang EF, Potts MB, Keles GE, Lamborn KR, Chang SM, Barbaro NM, Berger MS
• Neuronal responses to passive movement in the globus pallidus internus in primary dystonia.
  Journal of neurophysiology 2007 Chang EF, Turner RS, Ostrem JL, Davis VR, Starr PA
• Acute traumatic intraparenchymal hemorrhage: risk factors for progression in the early post-injury period.
  Neurosurgery 2007 Chang EF, Meeker M, Holland MC
• The role of early follow-up computed tomography imaging in the management of traumatic brain injury patients with intracranial hemorrhage.
  The Journal of trauma 2007 Smith JS, Chang EF, Rosenthal G, Meeker M, von Koch C, Manley GT, Holland MC
• Critical period window for spectral tuning defined in the primary auditory cortex (A1) in the rat.
  The Journal of neuroscience : the official journal of the Society for Neuroscience 2007 de Villers-Sidani E, Chang EF, Bao S, Merzenich MM
• Volumetric extent of resection and residual contrast enhancement on initial surgery as predictors of outcome in adult patients with hemispheric anaplastic astrocytoma.
  Journal of neurosurgery 2006 Keles GE, Chang EF, Lamborn KR, Tihan T, Chang CJ, Chang SM, Berger MS
• Acute traumatic intraparenchymal hemorrhage: risk factors for progression in the early post-injury period.
  Neurosurgery 2006 Chang EF, Meeker M, Holland MC
• The extended retrosigmoid approach: an alternative to radical cranial base approaches for posterior fossa lesions.
  Neurosurgery 2006 Quiñones-Hinojosa A, Chang EF, Lawton MT
• Focal cortical dysplasia: a review of pathological features, genetics, and surgical outcome.
  Neurosurgical focus 2006 Wang VY, Chang EF, Barbaro NM
• Development of spectral and temporal response selectivity in the auditory cortex.
  Proceedings of the National Academy of Sciences of the United States of America 2005 Chang EF, Bao S, Imaizumi K, Schreiner CE, Merzenich MM
• Thrombotic intracranial aneurysms: classification scheme and management strategies in 68 patients.
  Neurosurgery 2005 Lawton MT, Quiñones-Hinojosa A, Chang EF, Yu T
• Temporal plasticity in the primary auditory cortex induced by operant perceptual learning.
  Nature neuroscience 2004 Bao S, Chang EF, Woods J, Merzenich MM
• Intraoperative subcortical stimulation mapping for hemispherical perirolandic gliomas located within or adjacent to the descending motor pathways: evaluation of morbidity and assessment of functional outcome in 294 patients.
  Journal of neurosurgery 2004 Keles GE, Lundin DA, Lamborn KR, Chang EF, Ojemann G, Berger MS
• Renal cell carcinoma metastatic to the choroid mimicking intraventricular meningioma.
  The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques 2004 Quinones-Hinojosa A, Chang EF, Khan SA, Lawton MT, McDermott MW
• Progressive degradation and subsequent refinement of acoustic representations in the adult auditory cortex.
  The Journal of neuroscience : the official journal of the Society for Neuroscience 2003 Bao S, Chang EF, Davis JD, Gobeske KT, Merzenich MM
• Falcotentorial meningiomas: clinical, neuroimaging, and surgical features in six patients.
  Neurosurgical focus 2003 Quinones-Hinojosa A, Chang EF, McDermott MW
• Heme oxygenase-2 protects against lipid peroxidation-mediated cell loss and impaired motor recovery after traumatic brain injury.
  The Journal of neuroscience : the official journal of the Society for Neuroscience 2003 Chang EF, Wong RJ, Vreman HJ, Igarashi T, Galo E, Sharp FR, Stevenson DK, Noble-Haeusslein LJ
• Environmental noise retards auditory cortical development.
  Science (New York, N.Y.) 2003 Chang EF, Merzenich MM
• Isolated trigeminal nerve sarcoid granuloma mimicking trigeminal schwannoma: case report.
  Neurosurgery 2003 Quinones-Hinojosa A, Chang EF, Khan SA, McDermott MW