Duygu Kuzuoglu Ozturk, PhD
Assistant Professor
Urology
School of Medicine

Publications (10)

Top publication keywords:
5' Untranslated RegionsReceptors, AndrogenRNA, MessengerGene Expression Regulation, PlantRibonucleasesProstatic Neoplasms, Castration-ResistantArgonaute ProteinsMicroRNAsPoly(A)-Binding Protein IEukaryotic Initiation Factor-4AAndrogen Receptor AntagonistsTriticumProstatic NeoplasmsThiohydantoinsCaenorhabditis elegans Proteins

• Small-molecule RNA therapeutics to target prostate cancer.
  Cancer cell 2025 Kuzuoglu-Ozturk D, Nguyen HG, Xue L, Figueredo E, Subramanyam V, Liu I, Bonitto K, Noronha A, Dabrowska A, Cowan JE, Oses-Prieto JA, Burlingame AL, Worland ST, Carroll PR, Ruggero D
• Androgen Receptor Inhibition Increases MHC Class I Expression and Improves Immune Response in Prostate Cancer.
  Cancer discovery 2025 Chesner LN, Polesso F, Graff JN, Hawley JE, Smith AK, Lundberg A, Das R, Shenoy T, Sjöström M, Zhao F, Hu YM, Linder S, Chen WS, Hawkins RM, Shrestha R, Zhu X, Foye A, Li H, Kim LM, Bhalla M, O'…
• A CAF40-binding motif facilitates recruitment of the CCR4-NOT complex to mRNAs targeted by Drosophila Roquin.
  Nature communications 2017 Sgromo A, Raisch T, Bawankar P, Bhandari D, Chen Y, Kuzuoglu-Öztürk D, Weichenrieder O, Izaurralde E
• miRISC and the CCR4-NOT complex silence mRNA targets independently of 43S ribosomal scanning.
  The EMBO journal 2016 Kuzuoglu-Öztürk D, Bhandari D, Huntzinger E, Fauser M, Helms S, Izaurralde E
• A DDX6-CNOT1 complex and W-binding pockets in CNOT9 reveal direct links between miRNA target recognition and silencing.
  Molecular cell 2014 Chen Y, Boland A, Kuzuoglu-Öztürk D, Bawankar P, Loh B, Chang CT, Weichenrieder O, Izaurralde E

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• Structure and assembly of the NOT module of the human CCR4-NOT complex.
  Nature structural & molecular biology 2013 Boland A, Chen Y, Raisch T, Jonas S, Kuzuoglu-Öztürk D, Wohlbold L, Weichenrieder O, Izaurralde E
• GW182 proteins cause PABP dissociation from silenced miRNA targets in the absence of deadenylation.
  The EMBO journal 2013 Zekri L, Kuzuoglu-Öztürk D, Izaurralde E
• The interactions of GW182 proteins with PABP and deadenylases are required for both translational repression and degradation of miRNA targets.
  Nucleic acids research 2012 Huntzinger E, Kuzuoglu-Öztürk D, Braun JE, Eulalio A, Wohlbold L, Izaurralde E
• Autophagy-related gene, TdAtg8, in wild emmer wheat plays a role in drought and osmotic stress response.
  Planta 2012 Kuzuoglu-Ozturk D, Cebeci Yalcinkaya O, Akpinar BA, Mitou G, Korkmaz G, Gozuacik D, Budak H
• The Caenorhabditis elegans GW182 protein AIN-1 interacts with PAB-1 and subunits of the PAN2-PAN3 and CCR4-NOT deadenylase complexes.
  Nucleic acids research 2012 Kuzuoglu-Öztürk D, Huntzinger E, Schmidt S, Izaurralde E