Dongsheng Yang, PhD
Postdoctoral Scholar
Bioengineering
School of Pharmacy
🔬 Mechanism-Based Lesion Modeling: Developing PopPK and PK-PD frameworks to characterize lesion distribution and drug efficacy in tuberculosis (TB). 💊 Preclinical-to-Clinical Translation: Bridging in vitro/in vivo data with clinical trial simulations to optimize dosing regimens for novel anti-TB therapies.
Education & Training
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- Ph.D. Epidemiology Utrecht University 04/2022
Interests
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- Clinical Pharmacology
- Epidemiology
- Biostatistics
Publications (8)
Top publication keywords:
SulfonamidesLignansSwineCyclooctanesAnti-Infective AgentsLivestockChickensModels, BiologicalTrimethoprimDrug Resistance, BacterialFecesBacteriaPharmacokineticsPilocarpineAnti-Bacterial Agents
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PBPK Modeling: Empowering Drug Development and Precision Dosing in China.
CPT: pharmacometrics & systems pharmacology 2025 Yang D, Li J, Mak WY, Zheng A, Zhu X, He Q, Wang Y, Xiang X -
Physiologically Based Pharmacokinetic Modeling and Clinical Extrapolation for Topical Application of Pilocarpine on Eyelids: A Comprehensive Study.
Journal of pharmaceutical sciences 2024 Lin J, Bu F, Wu D, Jiang P, He Q, Yang D, Zhu X, Wang Y, Xiang X -
Modeling the complexity of drug-drug interactions: A physiologically-based pharmacokinetic study of Lenvatinib with Schisantherin A/Schisandrin A.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2024 Zheng A, Yang D, Pan C, He Q, Zhu X, Xiang X, Ji P -
The European livestock resistome.
mSystems 2024 Munk P, Yang D, Röder T, Maier L, Petersen TN, Duarte ASR, Clausen PTLC, Brinch C, Van Gompel L, Luiken R, Wagenaar JA, Schmitt H, Heederik DJJ, Mevius DJ, Smit LAM, EFFORT Consortium, Bossers A, … -
Antimicrobial resistance genes aph(3')-III, erm(B), sul2 and tet(W) abundance in animal faeces, meat, production environments and human faeces in Europe.
The Journal of antimicrobial chemotherapy 2022 Yang D, Heederik DJJ, Scherpenisse P, Van Gompel L, Luiken REC, Wadepohl K, Skarzynska M, Van Heijnsbergen E, Wouters IM, Greve GD, Jongerius-Gortemaker BGM, Tersteeg-Zijderveld M, Portengen L, … -
Risk factors for the abundance of antimicrobial resistance genes aph(3')-III, erm(B), sul2 and tet(W) in pig and broiler faeces in nine European countries.
The Journal of antimicrobial chemotherapy 2022 Yang D, Heederik DJJ, Mevius DJ, Scherpenisse P, Luiken REC, Van Gompel L, Skarzynska M, Wadepohl K, Chauvin C, Van Heijnsbergen E, Wouters IM, Greve GD, Jongerius-Gortemaker BGM, Tersteeg-Zijderveld … -
Risk Factors for Antimicrobial Resistance in Turkey Farms: A Cross-Sectional Study in Three European Countries.
Antibiotics (Basel, Switzerland) 2021 Horie M, Yang D, Joosten P, Munk P, Wadepohl K, Chauvin C, Moyano G, Skarzynska M, Dewulf J, Aarestrup FM, Blaha T, Sanders P, Gonzalez-Zorn B, Wasyl D, Wagenaar JA, Heederik D, Mevius D, Schmitt H, … -
Association of antimicrobial usage with faecal abundance of aph(3')-III, ermB, sul2 and tetW resistance genes in veal calves in three European countries.
International journal of antimicrobial agents 2020 Yang D, Van Gompel L, Luiken REC, Sanders P, Joosten P, van Heijnsbergen E, Wouters IM, Scherpenisse P, Chauvin C, Wadepohl K, Greve GD, Jongerius-Gortemaker BGM, Tersteeg-Zijderveld MHG, Soumet C, …