Donghwa Kim, PhD
Postdoctoral Scholar
Medicine
School of Medicine

Education & Training

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• PhD Pharmacy Seoul National University 05/2020
• BS Chemistry University of California, Berkeley 12/2014

Publications (61)

Top publication keywords:
TerpenesSmall Molecule LibrariesPolygonaceaeNeovascularization, PhysiologicProtein Kinase InhibitorsCyclin-Dependent Kinase 8TeaCinnamatesRadiation-Protective AgentsReceptor Protein-Tyrosine KinasesAntineoplastic Agents, PhytogenicUltraviolet RaysTriple Negative Breast NeoplasmsAngiogenesis InhibitorsCatechin

• Thiobarbiturate-Derived Compound MHY1025 Alleviates Renal Fibrosis by Modulating Oxidative Stress, Epithelial Inflammation, and Fibroblast Activation.
  Antioxidants (Basel, Switzerland) 2023 Kim J, Lee J, Yoon D, Son M, Kim MJ, Ha S, Kim D, Yoo JA, Kim D, Chung HY, Moon HR, Chung KW
• Dietary Nε-(carboxymethyl)lysine is a trigger of non-alcoholic fatty liver disease under high-fat consumption.
  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Lee HB, Choi JH, Kim D, Lee KW, Ha SK, Lee SH, Park HY
• TLR7 activation by miR-21 promotes renal fibrosis by activating the pro-inflammatory signaling pathway in tubule epithelial cells.
  Cell communication and signaling : CCS 2023 Kim J, Ha S, Son M, Kim D, Kim MJ, Kim B, Kim D, Chung HY, Chung KW
• Pathogenesis, Intervention, and Current Status of Drug Development for Sarcopenia: A Review.
  Biomedicines 2023 Jang JY, Kim D, Kim ND
• Recent Developments in Combination Chemotherapy for Colorectal and Breast Cancers with Topoisomerase Inhibitors.
  International journal of molecular sciences 2023 Jang JY, Kim D, Kim ND

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• Highly efficient thin-film 930 nm VCSEL on PDMS for biomedical applications.
  Scientific reports 2023 Kwon O, Moon S, Yun Y, Nam YH, Kim NH, Kim D, Choi W, Park S, Lee J
• Transcriptional regulation of Notch1 by nuclear factor-κB during T cell activation.
  Scientific reports 2023 Hwang JR, Kim D, Kang JA, Park SH, Park SG
• Clinical application of the Panbio™ COVID-19 Ag rapid test device and SSf-COVID19 kit for the detection of SARS-CoV-2 infection.
  BMC research notes 2022 Oh SM, Lee JS, Jo HJ, Kim D, Park D, Hwang YH, Choi Y, Lee CM, Lee S, Chang E, Lee E, Kim TS, Seong MW, Choe PG, Kim NJ
• Grabody B, an IGF1 receptor-based shuttle, mediates efficient delivery of biologics across the blood-brain barrier.
  Cell reports methods 2022 Shin JW, An S, Kim D, Kim H, Ahn J, Eom J, You WK, Yun H, Lee B, Sung B, Jung J, Kim S, Son Y, Sung E, Lee H, Lee S, Song D, Pak Y, Sandhu JK, Haqqani AS, Stanimirovic DB, Yoo J, Kim D, Maeng S, Lee J…
• Effect of intake manifold geometry on cylinder-to-cylinder variation and tumble enhancement in gasoline direct injection engine.
  Scientific reports 2022 Shin J, Kim D, Son Y, Park S
• Involvement of cell shape and lipid metabolism in glioblastoma resistance to temozolomide.
  Acta pharmacologica Sinica 2022 Choo M, Mai VH, Kim HS, Kim DH, Ku JL, Lee SK, Park CK, An YJ, Park S
• Antiproliferative Activity of a New Quinazolin-4(3H)-One Derivative via Targeting Aurora Kinase A in Non-Small Cell Lung Cancer.
  Pharmaceuticals (Basel, Switzerland) 2022 Lee JY, Yang H, Kim D, Kyaw KZ, Hu R, Fan Y, Lee SK
• Top-emitting 940-nm thin-film VCSELs transferred onto aluminum heatsinks.
  Scientific reports 2022 Moon S, Yun Y, Lee M, Kim D, Choi W, Park JY, Lee J
• Cinnamomum verum-derived O-methoxycinnamaldehyde prevents lipopolysaccharide-induced depressive-like behavior in mice via NFAT mRNA stability in T lymphocytes.
  Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Kim HJ, Kim H, Choi Y, Lee JH, Kim D, Lee SK, Park KS
• Novel Polymer-Based Organic/c-Si Monolithic Tandem Solar Cell: Enhanced Efficiency using Interlayer and Transparent Top Electrode Engineering.
  Macromolecular rapid communications 2021 Park H, Park SH, Lee SW, Kang Y, Kim D, Son HJ, Lee HS
• Discovery of Novel Small-Molecule Antiangiogenesis Agents to Treat Diabetic Retinopathy.
  Journal of medicinal chemistry 2021 Kim D, Choi SW, Cho J, Been JH, Choi K, Jiang W, Han J, Oh J, Park C, Choi S, Seo S, Kim KL, Suh W, Lee SK, Kim S
• Nitidumpeptins A and B, Cyclohexapeptides Isolated from Zanthoxylum nitidum var. tomentosum: Structural Elucidation, Total Synthesis, and Antiproliferative Activity in Cancer Cells.
  The Journal of organic chemistry 2021 Qin F, Wang CY, Kim D, Wang HS, Zhu YK, Lee SK, Yao GY, Liang D
• Historical Analysis of High-Efficiency, Large-Area Solar Cells: Toward Upscaling of Perovskite Solar Cells.
  Advanced materials (Deerfield Beach, Fla.) 2020 Lee SW, Bae S, Kim D, Lee HS
• Anti-Proliferative Activity of Nodosin, a Diterpenoid from Isodon serra, via Regulation of Wnt/β-Catenin Signaling Pathways in Human Colon Cancer Cells.
  Biomolecules & therapeutics 2020 Bae ES, Kim YM, Kim DH, Byun WS, Park HJ, Chin YW, Lee SK
• The PI3Kα inhibitor DFX24 suppresses tumor growth and metastasis in non-small cell lung cancer via ERK inhibition and EPHB6 reactivation.
  Pharmacological research 2020 Fan YH, Ding HW, Kim D, Liu JY, Hong JY, Xu YN, Wang D, Yang XS, Lee SK
• Publisher Correction: Perovskites fabricated on textured silicon surfaces for tandem solar cells.
  Communications chemistry 2020 Lee SW, Bae S, Hwang JK, Lee W, Lee S, Hyun JY, Cho K, Kim S, Heinz FD, Bin Choi S, Choi D, Kang D, Yang J, Jeong S, Park SJ, Schubert MC, Glunz S, Kim WM, Kang Y, Lee HS, Kim D
• Recent insights of T cell receptor-mediated signaling pathways for T cell activation and development.
  Experimental & molecular medicine 2020 Hwang JR, Byeon Y, Kim D, Park SG
• Cytotoxic Scalarane Sesterterpenes from the Sponge Hyrtioserectus.
  Marine drugs 2020 Kwon OS, Kim D, Kim CK, Sun J, Sim CJ, Oh DC, Lee SK, Oh KB, Shin J
• Overexpression of AGR2 Is Associated With Drug Resistance in Mutant Non-small Cell Lung Cancers.
  Anticancer research 2020 Luu TT, Bach DH, Kim D, Hu R, Park HJ, Lee SK
• Perovskites fabricated on textured silicon surfaces for tandem solar cells.
  Communications chemistry 2020 Lee SW, Bae S, Hwang JK, Lee W, Lee S, Hyun JY, Cho K, Kim S, Heinz FD, Bin Choi S, Choi D, Kang D, Yang J, Jeong S, Park SJ, Schubert MC, Glunz S, Kim WM, Kang Y, Lee HS, Kim D
• Prior acquired resistance to paclitaxel relays diverse EGFR-targeted therapy persistence mechanisms.
  Science advances 2020 Aldonza MBD, Ku J, Hong JY, Kim D, Yu SJ, Lee MS, Prayogo MC, Tan S, Kim D, Han J, Lee SK, Im SG, Ryu HS, Kim Y
• Photoprotective Activity of Topsentin, A Bis(Indole) Alkaloid from the Marine Sponge Spongosorites genitrix, by Regulation of COX-2 and Mir-4485 Expression in UVB-Irradiated Human Keratinocyte Cells.
  Marine drugs 2020 Hwang J, Kim D, Park JS, Park HJ, Shin J, Lee SK
• Photoprotective effects of 2S,3R-6-methoxycarbonylgallocatechin isolated from Anhua dark tea on UVB-induced inflammatory responses in human keratinocytes.
  Journal of photochemistry and photobiology. B, Biology 2019 Kim D, Hu R, Fan Y, Xu YN, Park HJ, Lee SK
• Glechomanamides A-C, Germacrane Sesquiterpenoids with an Unusual Δ8-7,12-Lactam Moiety from Salvia scapiformis and Their Antiangiogenic Activity.
  Journal of natural products 2019 Wang CY, Kim D, Zhu YK, Oh DC, Huang RZ, Wang HS, Liang D, Lee SK
• Antitumor Activity of Vanicoside B Isolated from Persicaria dissitiflora by Targeting CDK8 in Triple-Negative Breast Cancer Cells.
  Journal of natural products 2019 Kim D, Wang CY, Hu R, Lee JY, Luu TT, Park HJ, Lee SK
• Targeting Histone Methyltransferase DOT1L by a Novel Psammaplin A Analog Inhibits Growth and Metastasis of Triple-Negative Breast Cancer.
  Molecular therapy oncolytics 2019 Byun WS, Kim WK, Han HJ, Chung HJ, Jang K, Kim HS, Kim S, Kim D, Bae ES, Park S, Lee J, Park HG, Lee SK
• Neuroprotective effect of catechins derivatives isolated from Anhua dark tea on NMDA-induced excitotoxicity in SH-SY5Y cells.
  Fitoterapia 2019 Liu J, Fan Y, Kim D, Zhong T, Yi P, Fan C, Wang A, Yang X, Lee S, Ren X, Xu Y
• Therapeutic Potential of Rottlerin for Skin Hyperpigmentary Disorders by Inhibiting the Transcriptional Activity of CREB-Regulated Transcription Coactivators.
  The Journal of investigative dermatology 2019 Kim YH, Kim D, Hong AR, Kim JH, Yoo H, Kim J, Kim I, Kang SW, Chang SE, Song Y
• Antitumor Activity of DFX117 by Dual Inhibition of c-Met and PI3Kα in Non-Small Cell Lung Cancer.
  Cancers 2019 Fan Y, Ding H, Kim D, Bach DH, Hong JY, Xu Y, Lee SK
• AXL degradation in combination with EGFR-TKI can delay and overcome acquired resistance in human non-small cell lung cancer cells.
  Cell death & disease 2019 Kim D, Bach DH, Fan YH, Luu TT, Hong JY, Park HJ, Lee SK
• Camporidines A and B: Antimetastatic and Anti-inflammatory Polyketide Alkaloids from a Gut Bacterium of Camponotus kiusiuensis.
  Journal of natural products 2019 Hong SH, Ban YH, Byun WS, Kim D, Jang YJ, An JS, Shin B, Lee SK, Shin J, Yoon YJ, Oh DC
• Phenalenones from a Marine-Derived Fungus Penicillium Sp.
  Marine drugs 2019 Park SC, Julianti E, Ahn S, Kim D, Lee SK, Noh M, Oh DC, Oh KB, Shin AJ
• Bromopyrrole Alkaloids from the Sponge Agelas kosrae.
  Marine drugs 2018 Kwon OS, Kim D, Kim H, Lee YJ, Lee HS, Sim CJ, Oh DC, Lee SK, Oh KB, Shin J
• Quantitative Analysis and Band Gap Determination for CIGS Absorber Layers Using Surface Techniques.
  Journal of analytical methods in chemistry 2018 Jang YJ, Lee J, Lee KB, Kim D, Lee Y
• BMP4 Upregulation Is Associated with Acquired Drug Resistance and Fatty Acid Metabolism in EGFR-Mutant Non-Small-Cell Lung Cancer Cells.
  Molecular therapy. Nucleic acids 2018 Bach DH, Luu TT, Kim D, An YJ, Park S, Park HJ, Lee SK
• Skeletal Muscle Tissue Trib3 Links Obesity with Insulin Resistance by Autophagic Degradation of AKT2.
  Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018 Kwon M, Eom J, Kim D, Kim J, Heredia J, Kang SW, Song Y
• Complementary Characterization of Cu(In,Ga)Se₂ Thin-Film Photovoltaic Cells Using Secondary Ion Mass Spectrometry, Auger Electron Spectroscopy, and Atom Probe Tomography.
  Journal of nanoscience and nanotechnology 2018 Jang YJ, Lee J, Jeong JH, Lee KB, Kim D, Lee Y
• Targeting Nicotinamide N-Methyltransferase and miR-449a in EGFR-TKI-Resistant Non-Small-Cell Lung Cancer Cells.
  Molecular therapy. Nucleic acids 2018 Bach DH, Kim D, Bae SY, Kim WK, Hong JY, Lee HJ, Rajasekaran N, Kwon S, Fan Y, Luu TT, Shin YK, Lee J, Lee SK
• Optical Transmittance Enhancement of Flexible Copper Film Electrodes with a Wetting Layer for Organic Solar Cells.
  ACS applied materials & interfaces 2017 Zhao G, Song M, Chung HS, Kim SM, Lee SG, Bae JS, Bae TS, Kim D, Lee GH, Han SZ, Lee HS, Choi EA, Yun J
• Relationship between ion migration and interfacial degradation of CH3NH3PbI3 perovskite solar cells under thermal conditions.
  Scientific reports 2017 Kim S, Bae S, Lee SW, Cho K, Lee KD, Kim H, Park S, Kwon G, Ahn SW, Lee HM, Kang Y, Lee HS, Kim D
• Synthesis and biological activity of new phthalimides as potential anti-inflammatory agents.
  Bioorganic & medicinal chemistry 2017 Bach DH, Liu JY, Kim WK, Hong JY, Park SH, Kim D, Qin SN, Luu TT, Park HJ, Xu YN, Lee SK
• Anti-melanogenic activity of phytosphingosine via the modulation of the microphthalmia-associated transcription factor signaling pathway.
  Journal of dermatological science 2017 Jang EJ, Shin Y, Park HJ, Kim D, Jung C, Hong JY, Kim S, Lee SK
• UV Degradation and Recovery of Perovskite Solar Cells.
  Scientific reports 2016 Lee SW, Kim S, Bae S, Cho K, Chung T, Mundt LE, Lee S, Park S, Park H, Schubert MC, Glunz SW, Ko Y, Jun Y, Kang Y, Lee HS, Kim D
• Electric-Field-Induced Degradation of Methylammonium Lead Iodide Perovskite Solar Cells.
  The journal of physical chemistry letters 2016 Bae S, Kim S, Lee SW, Cho KJ, Park S, Lee S, Kang Y, Lee HS, Kim D
• Clinical Evaluation of Rapid Diagnostic Test Kit for Scrub Typhus with Improved Performance.
  Journal of Korean medical science 2016 Kim YJ, Park S, Premaratna R, Selvaraj S, Park SJ, Kim S, Kim D, Kim MS, Shin DH, Choi KC, Kwon SH, Seo W, Lee NT, Kim SH, Kang HK, Kim YW
• Electrocatalytic activity of NiO on silicon nanowires with a carbon shell and its application in dye-sensitized solar cell counter electrodes.
  Nanoscale 2016 Kim J, Jung CL, Kim M, Kim S, Kang Y, Lee HS, Park J, Jun Y, Kim D
• Multiplexed gas sensor based on heterogeneous metal oxide nanomaterial array enabled by localized liquid-phase reaction.
  ACS applied materials & interfaces 2015 Yang D, Fuadi MK, Kang K, Kim D, Li Z, Park I
• Focused energy field method for the localized synthesis and direct integration of 1D nanomaterials on microelectronic devices.
  Advanced materials (Deerfield Beach, Fla.) 2014 Yang D, Kim D, Ko SH, Pisano AP, Li Z, Park I
• Ag contact properties according to the front grid width and firing temperature for silicon solar cells.
  Journal of nanoscience and nanotechnology 2014 Kim S, Park S, Kim YD, Bae S, Boo H, Kim H, Lee KD, Tark SJ, Kim D
• Ultraconformal contact transfer of monolayer graphene on metal to various substrates.
  Advanced materials (Deerfield Beach, Fla.) 2014 Jung W, Kim D, Lee M, Kim S, Kim JH, Han CS
• Combination effects of peramivir and favipiravir against oseltamivir-resistant 2009 pandemic influenza A(H1N1) infection in mice.
  PloS one 2014 Park S, Kim JI, Lee I, Lee S, Hwang MW, Bae JY, Heo J, Kim D, Jang SI, Kim H, Cheong HJ, Song JW, Song KJ, Baek LJ, Park MS
• Effects of a hemagglutinin D222G substitution on the pathogenicity of 2009 influenza A (H1N1) virus in mice.
  Archives of virology 2014 Kim JI, Lee I, Park S, Lee S, Hwang MW, Bae JY, Heo J, Kim D, Jang SI, Song JW, Park MS
• The PDZ-binding motif of the avian NS1 protein affects transmission of the 2009 influenza A(H1N1) virus.
  Biochemical and biophysical research communications 2014 Kim JI, Hwang MW, Lee I, Park S, Lee S, Bae JY, Heo J, Kim D, Jang SI, Park MS, Kwon HJ, Song JW, Park MS
• Phylogenetic analysis of a swine influenza A(H3N2) virus isolated in Korea in 2012.
  PloS one 2014 Kim JI, Lee I, Park S, Lee S, Hwang MW, Bae JY, Heo J, Kim D, Jang SI, Kim K, Park MS
• DBA/2 mouse as an animal model for anti-influenza drug efficacy evaluation.
  Journal of microbiology (Seoul, Korea) 2013 Kim JI, Park S, Lee S, Lee I, Heo J, Hwang MW, Bae JY, Kim D, Jang SI, Park MS, Park MS
• Aronia melanocarpa and its components demonstrate antiviral activity against influenza viruses.
  Biochemical and biophysical research communications 2013 Park S, Kim JI, Lee I, Lee S, Hwang MW, Bae JY, Heo J, Kim D, Han SZ, Park MS