Diankun Yu, PhD
Postdoctoral Scholar
Pediatrics
School of Medicine

Publications (12)

Top publication keywords:
Adrenergic alpha-AgonistsHomeodomain ProteinsAutistic DisorderCerebral CortexNeuronsAction PotentialsMicrogliaReceptors, G-Protein-CoupledThalamusSeizuresPhosphatidylserinesAutism Spectrum DisorderParvalbuminsMice, TransgenicSynapses

• GPR56 S4 variant is required for microglia-mediated synaptic pruning.
  Glia 2022 Li T, Luo R, Schmidt R, D'Alessandro N, Kishore P, Zhu B, Yu D, Piao X
• Microglial GPR56 is the molecular target of maternal immune activation-induced parvalbumin-positive interneuron deficits.
  Science advances 2022 Yu D, Li T, Delpech JC, Zhu B, Kishore P, Koshi T, Luo R, Pratt KJB, Popova G, Nowakowski TJ, Villeda SA, Piao X
• Phospholipid-flippase chaperone CDC50A is required for synapse maintenance by regulating phosphatidylserine exposure.
  The EMBO journal 2021 Li T, Yu D, Oak HC, Zhu B, Wang L, Jiang X, Molday RS, Kriegstein A, Piao X
• The Transcription Factor Shox2 Shapes Neuron Firing Properties and Suppresses Seizures by Regulation of Key Ion Channels in Thalamocortical Neurons.
  Cerebral cortex (New York, N.Y. : 1991) 2021 Yu D, Febbo IG, Maroteaux MJ, Wang H, Song Y, Han X, Sun C, Meyer EE, Rowe S, Chen Y, Canavier CC, Schrader LA
• Cell type-specific evaluation of ADGRG1/GPR56 function in developmental central nervous system myelination.
  Glia 2020 Chiou B, Gao C, Giera S, Folts CJ, Kishore P, Yu D, Oak HC, Jiang R, Piao X

Show all (7 more) Hide

• A splicing isoform of GPR56 mediates microglial synaptic refinement via phosphatidylserine binding.
  The EMBO journal 2020 Li T, Chiou B, Gilman CK, Luo R, Koshi T, Yu D, Oak HC, Giera S, Johnson-Venkatesh E, Muthukumar AK, Stevens B, Umemori H, Piao X
• Astrocytes Amplify Neuronal Dendritic Volume Transmission Stimulated by Norepinephrine.
  Cell reports 2019 Chen C, Jiang Z, Fu X, Yu D, Huang H, Tasker JG
• BK channel deacetylation by SIRT1 in dentate gyrus regulates anxiety and response to stress.
  Communications biology 2018 Yu D, Homiack DR, Sawyer EJ, Schrader LA
• The transcription factor NeuroD2 coordinates synaptic innervation and cell intrinsic properties to control excitability of cortical pyramidal neurons.
  The Journal of physiology 2016 Chen F, Moran JT, Zhang Y, Ates KM, Yu D, Schrader LA, Das PM, Jones FE, Hall BJ
• A unique stylopod patterning mechanism by Shox2-controlled osteogenesis.
  Development (Cambridge, England) 2016 Ye W, Song Y, Huang Z, Osterwalder M, Ljubojevic A, Xu J, Bobick B, Abassah-Oppong S, Ruan N, Shamby R, Yu D, Zhang L, Cai CL, Visel A, Zhang Y, Cobb J, Chen Y
• A common Shox2-Nkx2-5 antagonistic mechanism primes the pacemaker cell fate in the pulmonary vein myocardium and sinoatrial node.
  Development (Cambridge, England) 2015 Ye W, Wang J, Song Y, Yu D, Sun C, Liu C, Chen F, Zhang Y, Wang F, Harvey RP, Schrader L, Martin JF, Chen Y
• The short stature homeobox 2 (Shox2)-bone morphogenetic protein (BMP) pathway regulates dorsal mesenchymal protrusion development and its temporary function as a pacemaker during cardiogenesis.
  The Journal of biological chemistry 2014 Sun C, Yu D, Ye W, Liu C, Gu S, Sinsheimer NR, Song Z, Li X, Chen C, Song Y, Wang S, Schrader L, Chen Y