Diane Wara, MD
Professor
Pediatrics
School of Medicine
Diane Wara, MD, is a professor emeritus of pediatrics in the Allergy/Immunology Bone Marrow Transplant Division, director of the Northern California Pediatric HIV Program, and a member of the leadership group for the NIAID-funded domestic and international clinical trials program in HIV (IMPAACT).
Show full bio (280 words) Hide full bio
Her work, along with that of others, led to the successful strategy for the interruption of perinatal transmission in the developed world. Currently, she is working through IMPAACT to extend and modify successful strategies to prevent transmission throughout the developing world. Dr. Wara has authored more than180 publications and, throughout her career, has focused her research on the pathogenesis and treatment strategies of pediatric immune deficiency syndromes (PIDD) and pediatric HIV. She contributed to reports of the first child with adenosine deaminase deficiency as well as treatment strategies for this disorder, including the successful gene transfer in neonates with known ADA deficiency; the first child with purine nucleoside phosphorylase deficiency; the first child with ZAP-70 deficiency; and mutations in IKK -gamma leading to NEMO syndrome. Dr. Wara contributed to reports of the first child with HIV, the first subject to acquire HIV from a blood transfusion, the first report of vertical transmission of hepatitis C, the role(s) of genetic factors as well as neutralizing antibody in the perinatal transmission of HIV as well as long-term progression; the detection and diagnosis of in-utero versus peripartum transmission. She reported the successful interruption of HIV perinatal transmission by the use of intrapartum AZT to the mother and infant prophylaxis for 6 weeks; she reported numerous successful HIV treatment strategies for children and youth. Dr. Wara led the Immunology Division and the UCSF Pediatric Clinical Research Center for over 25 years. She served as member and chair of two NIH study sections as well as member and chair of the NIH Recombinant DNA Advisory Committee (2002-2006). Dr. Wara was elected to the National Academy of Sciences, Institute of Medicine, in 1998.
Education & Training
Show all (2) Hide
- M.D. School of Medicine University of California Irvine 1969
- Residency School of Medicine University of California, San Francisco
Websites
Show all (1) Hide
- Clinical Profile at UCSF Benioff Children's Hospital (ucsfbenioffchildrens.org)
Grants and Projects
Show all (7) Hide
- General Clinical Research Center, NIH, 1974-2009
- General Clinical Research Center, NIH, 1974-2007
- Pediatric Clinical Research Center, NIH, 1981-2007
- Northern California Pediatrics AIDS Treatment Center, NIH, 1988-2007
- Bay Area Perinatal Aids Center, NIH, 1989-1994
- Bay Area Perinatal Aids Cohort Study, NIH, 1989-1993
- Immunological Sciences Study Section, NIH, 1985-1992
Publications (170)
Top publication keywords:
HIV-1EnterocolitisEye Infections, ViralHIV AntibodiesKeratoconjunctivitis SiccaThymosinPregnancy Complications, InfectiousGene Products, tatThymus HormonesAcquired Immunodeficiency SyndromeStrabismusHIV InfectionsInfectious Disease Transmission, VerticalAdenosine DeaminaseImmunologic Deficiency Syndromes
-
Brief Report: Markers of Spontaneous Preterm Delivery in Women Living With HIV: Relationship With Protease Inhibitors and Vitamin D.
Journal of acquired immune deficiency syndromes (1999) 2019 Weinberg A, Huo Y, Kacanek D, Patel K, Watts DH, Wara D, Hoffman RM, Klawitter J, Christians U, for IMPAACT P1025 Team -
Ophthalmic manifestations of perinatally acquired HIV in a US cohort of long-term survivors.
The British journal of ophthalmology 2014 Rutar T, Youm J, Porco T, Tilton N, Muskat M, McNamara N, Wara D -
Family adversity and autonomic reactivity association with immune changes in HIV-affected school children.
Psychosomatic medicine 2013 Thomas MR, Wara D, Saxton K, Truskier M, Chesney MA, Boyce WT -
The effect of prophylaxis on pediatric HIV costs.
AIDS care 2011 Wilson LS, Hensic L, Paoli CJ, Basu R, Christenson M, Moskowitz JT, Wara D -
Dendritic cells from humans with hypomorphic mutations in IKBKG/NEMO have impaired mitogen-activated protein kinase activity.
Human mutation 2011 Ma CA, Wang HY, Temmerman S, Zhao Y, Wu L, Hornung RL, Wara D, Jain A
Show all (165 more) Hide
-
Anti-influenza serum and mucosal antibody responses after administration of live attenuated or inactivated influenza vaccines to HIV-infected children.
Journal of acquired immune deficiency syndromes (1999) 2010 Weinberg A, Song LY, Walker R, Allende M, Fenton T, Patterson-Bartlett J, Nachman S, Kemble G, Yi TT, Defechereux P, Wara D, Read JS, Levin M, IMPAACT P1057 Team -
Pediatric HIV costs across three treatment eras from 1986 to 2007.
Pediatrics 2010 Wilson LS, Basu R, Christenson M, Hensic L, Paoli C, Wara D, Moskowitz JT -
Persistent systemic inflammation and atypical enterocolitis in patients with NEMO syndrome.
Clinical immunology (Orlando, Fla.) 2009 Cheng LE, Kanwar B, Tcheurekdjian H, Grenert JP, Muskat M, Heyman MB, McCune JM, Wara DW -
Altered iron metabolism in children with human immunodeficiency virus disease.
Pediatric hematology and oncology 2009 Butensky James E, Harmatz P, Lee M, Kennedy C, Petru A, Wara D, Miaskowski C -
Regulatory T cells and their role in rheumatic diseases: a potential target for novel therapeutic development.
Pediatric rheumatology online journal 2008 Milojevic D, Nguyen KD, Wara D, Mellins ED -
Population pharmacokinetics of lamivudine in human immunodeficiency virus-exposed and -infected infants.
Antimicrobial agents and chemotherapy 2007 Tremoulet AH, Capparelli EV, Patel P, Acosta EP, Luzuriaga K, Bryson Y, Wara D, Zorrilla C, Holland D, Mirochnick M, Pediatric AIDS Clinical Trials Group -
Phase I/II trial of intermittent subcutaneous IL-2 administration in pediatric patients with moderate immune suppression: results of Pediatric AIDS Clinical Trials Study 402.
The Journal of allergy and clinical immunology 2007 Pahwa S, Muresan P, Sleasman J, Fenton T, Moye J, Deveikis A, Wara D, Van Dyke R, Pediatric Aids Clinical Trials Study 402 team -
JC virus granule cell neuronopathy in a child with CD40 ligand deficiency.
Pediatric neurology 2007 Hecht JH, Glenn OA, Wara DW, Wu YW -
Pharmacokinetics and safety of indinavir in human immunodeficiency virus-infected pregnant women.
Antimicrobial agents and chemotherapy 2006 Unadkat JD, Wara DW, Hughes MD, Mathias AA, Holland DT, Paul ME, Connor J, Huang S, Nguyen BY, Watts DH, Mofenson LM, Smith E, Deutsch P, Kaiser KA, Tuomala RE -
Index of suspicion.
Pediatrics in review 2006 Taylor Z, Butani L, Blumberg D, Cowan M, Wara D, Gopal S, Gavrilita C, Da-Silva S -
Impaired integrin-dependent function in Wiskott-Aldrich syndrome protein-deficient murine and human neutrophils.
Immunity 2006 Zhang H, Schaff UY, Green CE, Chen H, Sarantos MR, Hu Y, Wara D, Simon SI, Lowell CA -
Antibody responses to hepatitis A virus vaccine in HIV-infected children with evidence of immunologic reconstitution while receiving highly active antiretroviral therapy.
The Journal of infectious diseases 2005 Weinberg A, Gona P, Nachman SA, Defechereux P, Yogev R, Hughes W, Wara D, Spector SA, Read J, Elgie C, Cooper M, Dankner W, Pediatric AIDS Clinical Trials Group 1008 Team -
Long-term efficacy of enzyme replacement therapy for adenosine deaminase (ADA)-deficient severe combined immunodeficiency (SCID).
Clinical immunology (Orlando, Fla.) 2005 Chan B, Wara D, Bastian J, Hershfield MS, Bohnsack J, Azen CG, Parkman R, Weinberg K, Kohn DB -
Perinatal transmission of multidrug-resistant HIV-1 despite viral suppression on an enfuvirtide-based treatment regimen.
AIDS (London, England) 2005 Cohan D, Feakins C, Wara D, Petru A, McNicholl I, Schillinger D, Lu J, Kuritzkes D, Deeks SG -
Thrombosis and pediatric Wegener's granulomatosis: acquired and genetic risk factors for hypercoagulability.
Arthritis and rheumatism 2003 von Scheven E, Lu TT, Emery HM, Elder ME, Wara DW -
Lymphocyte subsets in healthy children from birth through 18 years of age: the Pediatric AIDS Clinical Trials Group P1009 study.
The Journal of allergy and clinical immunology 2003 Shearer WT, Rosenblatt HM, Gelman RS, Oyomopito R, Plaeger S, Stiehm ER, Wara DW, Douglas SD, Luzuriaga K, McFarland EJ, Yogev R, Rathore MH, Levy W, Graham BL, Spector SA, Pediatric AIDS Clinical … -
When the time comes to talk about HIV: factors associated with diagnostic disclosure and emotional distress in HIV-infected children.
Journal of acquired immune deficiency syndromes (1999) 2002 Lester P, Chesney M, Cooke M, Weiss R, Whalley P, Perez B, Glidden D, Petru A, Dorenbaum A, Wara D -
Safety of 2 recombinant human immunodeficiency virus type 1 (HIV-1) envelope vaccines in neonates born to HIV-1-infected women.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2001 Cunningham CK, Wara DW, Kang M, Fenton T, Hawkins E, McNamara J, Mofenson L, Duliege AM, Francis D, McFarland EJ, Borkowsky W, Pediatric AIDS Clinical Trials Group 230 Collaborators -
Ensuring the success of women faculty at AMCs: lessons learned from the National Centers of Excellence in Women's Health.
Academic medicine : journal of the Association of American Medical Colleges 2001 Morahan PS, Voytko ML, Abbuhl S, Means LJ, Wara DW, Thorson J, Cotsonas CE -
Recombinant CD4-IgG2 in human immunodeficiency virus type 1-infected children: phase 1/2 study. The Pediatric AIDS Clinical Trials Group Protocol 351 Study Team.
The Journal of infectious diseases 2000 Shearer WT, Israel RJ, Starr S, Fletcher CV, Wara D, Rathore M, Church J, DeVille J, Fenton T, Graham B, Samson P, Staprans S, McNamara J, Moye J, Maddon PJ, Olson WC -
A novel X-linked disorder of immune deficiency and hypohidrotic ectodermal dysplasia is allelic to incontinentia pigmenti and due to mutations in IKK-gamma (NEMO).
American journal of human genetics 2000 Zonana J, Elder ME, Schneider LC, Orlow SJ, Moss C, Golabi M, Shapira SK, Farndon PA, Wara DW, Emmal SA, Ferguson BM -
Genetic analysis of viral variants selected in transmission of human immunodeficiency viruses to newborns.
AIDS research and human retroviruses 2000 Kliks S, Contag CH, Corliss H, Learn G, Rodrigo A, Wara D, Mullins JI, Levy JA -
Shipment impairs lymphocyte proliferative responses to microbial antigens.
Clinical and diagnostic laboratory immunology 2000 Betensky RA, Connick E, Devers J, Landay AL, Nokta M, Plaeger S, Rosenblatt H, Schmitz JL, Valentine F, Wara D, Weinberg A, Lederman HM -
Need for an external proficiency testing program for cytokines, chemokines, and plasma markers of immune activation.
Clinical and diagnostic laboratory immunology 2000 Fahey JL, Aziz N, Spritzler J, Plaeger S, Nishanian P, Lathey JL, Seigel J, Landay AL, Kilarui R, Schmitz JL, White C, Wara DW, Akridge R, Cutili J, Douglas SD, Reuben J, Shearer WT, Nokta M, Polland … -
Lymphoproliferative responses to recombinant HIV-1 envelope antigens in neonates and infants receiving gp120 vaccines. AIDS Clinical Trial Group 230 Collaborators.
The Journal of infectious diseases 2000 Borkowsky W, Wara D, Fenton T, McNamara J, Kang M, Mofenson L, McFarland E, Cunningham C, Duliege AM, Francis D, Bryson Y, Burchett S, Spector SA, Frenkel LM, Starr S, Van Dyke R, Jimenez E -
Oral manifestations and dental status in paediatric HIV infection.
International journal of paediatric dentistry 2000 Ramos-Gomez FJ, Petru A, Hilton JF, Canchola AJ, Wara D, Greenspan JS -
Use of human immunodeficiency virus (HIV) human hyperimmune immunoglobulin in HIV type 1-infected children (Pediatric AIDS clinical trials group protocol 273).
The Journal of infectious diseases 2000 Stiehm ER, Fletcher CV, Mofenson LM, Palumbo PE, Kang M, Fenton T, Sapan CV, Meyer WA, Shearer WT, Hawkins E, Fowler MG, Bouquin P, Purdue L, Sloand EM, Nemo GJ, Wara D, Bryson YJ, Starr SE, Petru A, … -
Cytokine profile of a long-term pediatric HIV survivor with hyper-IgE syndrome and a normal CD4 T-cell count.
The Journal of allergy and clinical immunology 1999 Seroogy CM, Wara DW, Bluth MH, Dorenbaum A, White C, Durkin HG, Elder ME -
Pharmacokinetics of dapsone administered daily and weekly in human immunodeficiency virus-infected children.
Antimicrobial agents and chemotherapy 1999 Mirochnick M, Cooper E, McIntosh K, Xu J, Lindsey J, Jacobus D, Mofenson L, Sullivan JL, Dankner W, Frenkel LM, Nachman S, Wara DW, Johnson D, Bonagura VR, Rathore MH, Cunningham CK, McNamara J -
Sleep disturbances in children with human immunodeficiency virus infection.
Pediatrics 1999 Franck LS, Johnson LM, Lee K, Hepner C, Lambert L, Passeri M, Manio E, Dorenbaum A, Wara D -
Immunization with envelope MN rgp120 vaccine in human immunodeficiency virus-infected pregnant women.
The Journal of infectious diseases 1999 Wright PF, Lambert JS, Gorse GJ, Hsieh RH, McElrath MJ, Weinhold K, Wara DW, Anderson EL, Keefer MC, Jackson S, Wagner LJ, Francis DP, Fast PE, McNamara J -
Amendment to Clinical Research Project. Project 90-C-195. April 1, 1993. Treatment of severe combined immunodeficiency disease (SCID) due to adenosine deaminase deficiency with autologous lymphocytes transduced with a human ADA gene.
Human gene therapy 1999 Dunbar C, Chang L, Mullen C, Ramsey WJ, Carter C, Kohn D, Parkman R, Lenarsky C, Weinberg K, Wara D, Culver KW, Anderson WF, Leitman S, Fleisher T, Klein H, Shearer G, Clerici M, McGarrity G, Bastian … -
Planning for children whose parents are dying of HIV/AIDS. American Academy of Pediatrics. Committee on Pediatric AIDS, 1998-1999.
Pediatrics 1999 Wilfert C, Aronson JE, Beck DT, Fleischman AR, Kline MW, Mofenson LM, Scott GB, Wara DW, Whitley-Williams PN -
Safety and immunogenicity of HIV recombinant envelope vaccines in HIV-infected infants and children. National Institutes of Health-sponsored Pediatric AIDS Clinical Trials Group (ACTG-218).
Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association 1998 Lambert JS, McNamara J, Katz SL, Fenton T, Kang M, VanCott TC, Livingston R, Hawkins E, Moye J, Borkowsky W, Johnson D, Yogev R, Duliege AM, Francis D, Gershon A, Wara D, Martin N, Levin M, McSherry G… -
A randomized study of combined zidovudine-lamivudine versus didanosine monotherapy in children with symptomatic therapy-naive HIV-1 infection. The Pediatric AIDS Clinical Trials Group Protocol 300 Study Team.
The Journal of pediatrics 1998 McKinney RE, Johnson GM, Stanley K, Yong FH, Keller A, O'Donnell KJ, Brouwers P, Mitchell WG, Yogev R, Wara DW, Wiznia A, Mofenson L, McNamara J, Spector SA -
T lymphocytes with a normal ADA gene accumulate after transplantation of transduced autologous umbilical cord blood CD34+ cells in ADA-deficient SCID neonates.
Nature medicine 1998 Kohn DB, Hershfield MS, Carbonaro D, Shigeoka A, Brooks J, Smogorzewska EM, Barsky LW, Chan R, Burotto F, Annett G, Nolta JA, Crooks G, Kapoor N, Elder M, Wara D, Bowen T, Madsen E, Snyder FF, Bastian… -
CD8 cell noncytotoxic antiviral activity in human immunodeficiency virus-infected and -uninfected children.
The Journal of infectious diseases 1998 Levy JA, Hsueh F, Blackbourn DJ, Wara D, Weintrub PS -
Funding for patient-oriented research. Critical strain on a fundamental linchpin.
JAMA 1997 Williams GH, Wara DW, Carbone P -
Influence of HLA alleles on the rate of progression of vertically transmitted HIV infection in children: association of several HLA-DR13 alleles with long-term survivorship and the potential association of HLA-A*2301 with rapid progression to AIDS. Long-Term Survivor Study.
Human immunology 1997 Chen Y, Winchester R, Korber B, Gagliano J, Bryson Y, Hutto C, Martin N, McSherry G, Petru A, Wara D, Ammann A -
Comparative trial of two dosages of zalcitabine in zidovudine-experienced children with advanced human immunodeficiency virus disease. Pediatric AIDS Clinical Trials Group.
The Pediatric infectious disease journal 1997 Spector SA, Blanchard S, Wara DW, Oleske JM, McIntosh K, Hodes D, Dankner WM, Salgo M, McNamara J -
Transmission of HIV-1 in infants born to seropositive mothers: PCR-amplified proviral DNA detected by flow cytometric analysis of immunoreactive beads.
Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association 1997 Dorenbaum A, Venkateswaran KS, Yang G, Comeau AM, Wara D, Vyas GN -
A descriptive survey of pediatric human immunodeficiency virus-infected long-term survivors.
Pediatrics 1997 Nielsen K, McSherry G, Petru A, Frederick T, Wara D, Bryson Y, Martin N, Hutto C, Ammann AJ, Grubman S, Oleske J, Scott GB -
Life events, frontal electroencephalogram laterality, and functional immune status after acute psychological stressors in adolescents.
Psychosomatic medicine 1997 Liang SW, Jemerin JM, Tschann JM, Wara DW, Boyce WT -
Clinical and laboratory characteristics of a large cohort of symptomatic, human immunodeficiency virus-infected infants and children. AIDS Clinical Trials Group Protocol 152 Study Team.
The Pediatric infectious disease journal 1996 Englund JA, Baker CJ, Raskino C, McKinney RE, Lifschitz MH, Petrie B, Fowler MG, Connor JD, Mendez H, O'Donnell K, Wara DW -
The utility of IgA antibody to human immunodeficiency virus type 1 in early diagnosis of vertically transmitted infection. National Institute of Allergy and Infectious Diseases and National Institute of Child Health and Human Development Women and Infants Transmission Study Group.
Archives of pediatrics & adolescent medicine 1996 McIntosh K, Comeau AM, Wara D, Diaz C, Landesman S, Pitt J, Rich K, Lew J, Moye J, Kalish LA -
Toxicities of total-body irradiation for pediatric bone marrow transplantation.
International journal of radiation oncology, biology, physics 1996 Chou RH, Wong GB, Kramer JH, Wara DW, Matthay KK, Crittenden MR, Swift PS, Cowan MJ, Wara WM -
Adrenocortical and behavioral predictors of immune responses to starting school.
Pediatric research 1995 Boyce WT, Adams S, Tschann JM, Cohen F, Wara D, Gunnar MR -
Life events, cardiovascular reactivity, and risk behavior in adolescent boys.
Pediatrics 1995 Liang SW, Jemerin JM, Tschann JM, Irwin CE, Wara DW, Boyce WT -
Influence of host genotype on progression to acquired immunodeficiency syndrome among children infected with human immunodeficiency virus type 1.
The Journal of pediatrics 1995 Just JJ, Abrams E, Louie LG, Urbano R, Wara D, Nicholas SW, Stein Z, King MC -
Severe combined immunodeficiency with absence of peripheral blood CD8+ T cells due to ZAP-70 deficiency.
Cellular immunology 1995 Elder ME, Hope TJ, Parslow TG, Umetsu DT, Wara DW, Cowan MJ -
Psychobiologic reactivity to stress and childhood respiratory illnesses: results of two prospective studies.
Psychosomatic medicine 1995 Boyce WT, Chesney M, Alkon A, Tschann JM, Adams S, Chesterman B, Cohen F, Kaiser P, Folkman S, Wara D -
Recurrent Staphylococcus aureus renal abscess in a child positive for the human immunodeficiency virus.
Urology 1995 Brandeis JM, Baskin LS, Kogan BA, Wara D, Dorenbaum A -
A controlled trial of intravenous immune globulin for the prevention of serious bacterial infections in children receiving zidovudine for advanced human immunodeficiency virus infection. Pediatric AIDS Clinical Trials Group.
The New England journal of medicine 1994 Spector SA, Gelber RD, McGrath N, Wara D, Barzilai A, Abrams E, Bryson YJ, Dankner WM, Livingston RA, Connor EM -
HIV-1 Tat induces cytokine synthesis by uninfected mononuclear cells.
AIDS (London, England) 1994 Rautonen N, Rautonen J, Martin NL, Wara DW -
Features of HIV-1 that could influence maternal-child transmission.
JAMA 1994 Kliks SC, Wara DW, Landers DV, Levy JA -
Association between anti-human immunodeficiency virus type 1 (HIV-1) antibody-dependent cellular cytotoxicity antibody titers at birth and vertical transmission of HIV-1.
The Journal of infectious diseases 1994 Jenkins M, Landers D, Williams-Herman D, Wara D, Viscarello RR, Hammill HA, Kline MW, Shearer WT, Charlebois ED, Kohl S -
HIV type 1 Tat protein induces immunoglobulin and interleukin 6 synthesis by uninfected peripheral blood mononuclear cells.
AIDS research and human retroviruses 1994 Rautonen J, Rautonen N, Martin NL, Wara DW -
Antibodies in HIV Tat in Kawasaki disease.
Lancet (London, England) 1994 Rautonen N, White C, Martin NL, Wara DW, Salo E, Pelkonen P, Rautonen J -
Anti-tetanus toxoid antibody production after mismatched T cell-depleted bone marrow transplantation.
Journal of clinical immunology 1994 Benkerrou M, Wara DW, Elder M, Dror Y, Merino A, Colombe BW, Garovoy M, Cowan MJ -
Performance evaluation in multicenter clinical trials: development of a model by the AIDS Clinical Trials Group.
Controlled clinical trials 1993 Rosendorf LL, Dafni U, Amato DA, Lunghofer B, Bartlett JG, Leedom JM, Wara DW, Armstrong JA, Godfrey E, Sukkestad E -
Maternal transmission and diagnosis of human immunodeficiency virus during infancy.
Annals of the New York Academy of Sciences 1993 Wara DW, Luzuriaga K, Martin NL, Sullivan JL, Bryson YJ -
Immunologic changes occurring at kindergarten entry predict respiratory illnesses after the Loma Prieta earthquake.
Journal of developmental and behavioral pediatrics : JDBP 1993 Boyce WT, Chesterman EA, Martin N, Folkman S, Cohen F, Wara D -
Immune reconstitution in severe combined immunodeficiency disease after lectin-treated, T-cell-depleted haplocompatible bone marrow transplantation.
Blood 1993 Dror Y, Gallagher R, Wara DW, Colombe BW, Merino A, Benkerrou M, Cowan MJ -
Serum levels of soluble CD8, neopterin, beta 2-microglobulin and p24 antigen as indicators of disease progression in children with AIDS on zidovudine therapy.
AIDS (London, England) 1993 Siller L, Martin NL, Kostuchenko P, Beckett L, Rautonen J, Cheng SC, Wara DW -
Failure of intravenous pentamidine prophylaxis for Pneumocystis carinii pneumonia.
The Journal of pediatrics 1993 Weintrub PS, Wara DW, Duliege AM -
Low number of antibody producing cells in patients with sickle cell anemia.
Immunology letters 1992 Rautonen N, Martin NL, Rautonen J, Rooks Y, Mentzer WC, Wara DW -
Proposed definitions for in utero versus intrapartum transmission of HIV-1.
The New England journal of medicine 1992 Bryson YJ, Luzuriaga K, Sullivan JL, Wara DW -
Natural history of HIV-associated salivary gland disease.
Oral surgery, oral medicine, and oral pathology 1992 Schiødt M, Dodd CL, Greenspan D, Daniels TE, Chernoff D, Hollander H, Wara D, Greenspan JS -
Heterogeneity in the clastogenic response to X-rays in lymphocytes from ataxia-telangiectasia heterozygotes and controls.
Cancer causes & control : CCC 1992 Wiencke JK, Wara DW, Little JB, Kelsey KT -
Genetic risk factors for perinatally acquired HIV-1 infection.
Paediatric and perinatal epidemiology 1992 Just J, Louie L, Abrams E, Nicholas SW, Wara D, Stein Z, King MC -
A screening test for the detection of anti-HIV-1 IgA in young infants.
Immunological investigations 1992 Martin NL, Rautonen J, Crombleholme W, Rautonen N, Wara DW -
Neutrophil function screening in patients with chronic granulomatous disease by a flow cytometric method.
Cytometry 1992 Epling CL, Stites DP, McHugh TM, Chong HO, Blackwood LL, Wara DW -
Serum interleukin-6 concentrations are elevated and associated with elevated tumor necrosis factor-alpha and immunoglobulin G and A concentrations in children with HIV infection.
AIDS (London, England) 1991 Rautonen J, Rautonen N, Martin NL, Philip R, Wara DW -
Vertical transmission of hepatitis C virus.
Lancet (London, England) 1991 Thaler MM, Park CK, Landers DV, Wara DW, Houghton M, Veereman-Wauters G, Sweet RL, Han JH -
Neopterin in diagnosis of human immunodeficiency virus infection in infants.
Journal of clinical microbiology 1991 Rautonen J, Martin NI, Rautonen N, Wara DW -
Detection of infection with human immunodeficiency virus (HIV) type 1 in infants by an anti-HIV immunoglobulin A assay using recombinant proteins.
The Journal of pediatrics 1991 Martin NL, Levy JA, Legg H, Weintrub PS, Cowan MJ, Wara DW -
Total body irradiation and bone marrow transplantation for immunodeficiency disorders in young children.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 1990 Halberg FE, Wara WM, Weaver KE, Wara DW, Ablin AR, Matthay KK, Mentzer WC, O'Leary MC, Cowan MJ -
ATFresno: a phenotype linking ataxia-telangiectasia with the Nijmegen breakage syndrome.
American journal of human genetics 1989 Curry CJ, O'Lague P, Tsai J, Hutchison HT, Jaspers NG, Wara D, Gatti RA, Hutchinson HT -
Parotid gland enlargement and xerostomia associated with labial sialadenitis in HIV-infected patients.
Journal of autoimmunity 1989 Schiødt M, Greenspan D, Daniels TE, Nelson J, Leggott PJ, Wara DW, Greenspan JS -
Polymerase chain reaction compared with concurrent viral cultures for rapid identification of human immunodeficiency virus infection among high-risk infants and children.
The Journal of pediatrics 1989 Edwards JR, Ulrich PP, Weintrub PS, Cowan MJ, Levy JA, Wara DW, Vyas GN -
Oral manifestations of pediatric AIDS.
Pediatrician 1989 Silverman S, Wara D -
Maternally transmitted HIV infection in children.
AIDS (London, England) 1988 Cowan MJ, Walker C, Culver K, Weintrub PS, Wara DW, Levy JA -
Production of lymphotoxin and tumor necrosis factor by human neonatal mononuclear cells.
Pediatric research 1988 English BK, Burchett SK, English JD, Ammann AJ, Wara DW, Wilson CB -
Rejection of bone marrow transplant and resistance of alloantigen reactive cells to in vivo deoxyadenosine in adenosine deaminase deficiency.
Clinical immunology and immunopathology 1988 Cowan MJ, Shannon KM, Wara DW, Ammann AJ -
Naproxen nephrotoxicity in a 2-year-old child.
American journal of diseases of children (1960) 1988 Ray PE, Rigolizzo D, Wara DR, Piel CF -
Lymphocyte abnormalities in infants born to drug-abusing mothers.
The Journal of pediatrics 1987 Culver KW, Ammann AJ, Partridge JC, Wong DF, Wara DW, Cowan MJ -
Guidelines for the control of perinatally transmitted human immunodeficiency virus infection and care of infected mothers, infants and children.
The Western journal of medicine 1987 Rutherford GW, Oliva GE, Grossman M, Green JR, Wara DW, Shaw NS, Echenberg DF, Wofsy CB, Weinstein DH, Stroud F -
Oral manifestation of primary and acquired immunodeficiency diseases in children.
Pediatric dentistry 1987 Leggott PJ, Robertson PB, Greenspan D, Wara DW, Greenspan JS -
Haploidentical bone marrow transplantation using soybean agglutinin-processed, T-depleted marrow.
Transplantation proceedings 1987 Matthay K, Wara DW, Ablin AJ, Cowan MJ -
Lymphocyte reconstitution in children receiving soybean agglutinin T-depleted bone marrow transplants.
Transplantation proceedings 1987 Cowan MJ, McHugh T, Smith W, Wara D, Matthay K, Ablin A, Casavant C, Stites D -
Alpha-fetoprotein levels in immunodeficiency.
The New England journal of medicine 1986 Ammann AJ, Cowan M, Wara D, Heyman M, Thaler MM, Buckley R, Lawton A, Vogler LB, Hirschhorn R -
Development of serum IgG subclass levels in children.
Monographs in allergy 1986 Lee SI, Heiner DC, Wara D -
Haploidentical bone marrow transplantation for severe combined immunodeficiency disease using soybean agglutinin-negative, T-depleted marrow cells.
Journal of clinical immunology 1985 Cowan MJ, Wara DW, Weintrub PS, Pabst H, Ammann AJ -
Deoxycytidine therapy in two patients with adenosine deaminase deficiency and severe immunodeficiency disease.
Clinical immunology and immunopathology 1985 Cowan MJ, Wara DW, Ammann AJ -
Behçet syndrome.
The Journal of pediatrics 1985 Ammann AJ, Johnson A, Fyfe GA, Leonards R, Wara DW, Cowan MJ -
Immune regulation: what immunodeficiency disease has taught us.
The Journal of investigative dermatology 1985 Wara DW -
Maternal-fetal transfer of pneumococcal capsular polysaccharide antibodies.
American journal of diseases of children (1960) 1985 Chudwin DS, Wara DW, Schiffman G, Artrip SG, Ammann AJ -
Epstein-Barr (EB) virus infection in homosexual men in London.
The British journal of venereal diseases 1984 Crawford DH, Weller I, Iliescu V, Wara DW -
Prenatal diagnosis of chronic granulomatous disease.
American journal of medical genetics 1984 Matthay KK, Golbus MS, Wara DW, Mentzer WC -
Comparison of high-dose and low-dose intravenous immunoglobulin therapy in patients with primary immunodeficiency diseases.
The American journal of medicine 1984 Ochs HD, Fischer SH, Wedgwood RJ, Wara DW, Cowan MJ, Ammann AJ, Saxon A, Budinger MD, Allred RU, Rousell RH -
Maternal transmission of acquired immune deficiency syndrome.
Pediatrics 1984 Cowan MJ, Hellmann D, Chudwin D, Wara DW, Chang RS, Ammann AJ -
Intravenous deoxycytidine therapy in a patient with adenosine deaminase deficiency.
Advances in experimental medicine and biology 1984 Cowan MJ, Martin DW, Wara DW, Ammann AJ -
Pediatric acquired immunodeficiency syndrome.
Annals of the New York Academy of Sciences 1984 Ammann AJ, Wara DW, Cowan MJ -
Significance of a positive antinuclear antibody test in a pediatric population.
American journal of diseases of children (1960) 1983 Chudwin DS, Ammann AJ, Cowan MJ, Wara DW -
Chronic active Epstein-Barr virus infections in two immunodeficient patients.
The Journal of pediatrics 1983 Hellmann D, Cowan MJ, Ammann AJ, Wara DW, Chudwin D, Chang RS -
Response of agranulocytosis to prolonged antithymocyte globulin therapy.
The Journal of pediatrics 1983 Chudwin DS, Cowan MJ, Greenberg PL, Wara DW, Ammann AJ -
Clinical and laboratory findings in childhood mixed connective tissue disease: presence of antibody to ribonucleoprotein containing the small nuclear ribonucleic acid U1.
The Journal of pediatrics 1983 Savouret JF, Chudwin DS, Wara DW, Ammann AJ, Cowan MJ, Miller WL -
Acquired immunodeficiency in an infant: possible transmission by means of blood products.
Lancet (London, England) 1983 Ammann AJ, Cowan MJ, Wara DW, Weintrub P, Dritz S, Goldman H, Perkins HA -
Effect of antibody concentration on opsonic requirements for phagocytosis in vitro of Streptococcus pneumoniae types 7 and 19.
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.) 1983 Chudwin DS, Wara DW, Lameris-Martin NB, Ammann AJ -
Dipyridamole and intravenous deoxycytidine therapy in a patient with adenosine deaminase deficiency.
Birth defects original article series 1983 Ammann AJ, Cowan MJ, Martin DW, Wara DW -
Increased serum opsonic activity and antibody concentration in patients with sickle cell disease after pneumococcal polysaccharide immunization.
The Journal of pediatrics 1983 Chudwin DS, Wara DW, Matthay KK, Caulfield MH, Schiffmann G, Mentzer WC, Ammann AJ -
Patients with abnormal proportions of T-lymphocyte subsets have reduced in vitro cellular immunity.
Clinical immunology and immunopathology 1983 Chudwin DS, Cowan MJ, Wara DW, Ammann AJ -
Aspergillus pneumonia in chronic granulomatous disease: recurrence and long-term outcome.
Acta paediatrica Scandinavica 1982 Chudwin DS, Wara DW, Cowan MJ, Ammann AJ -
The DiGeorge syndrome and the fetal alcohol syndrome.
American journal of diseases of children (1960) 1982 Ammann AJ, Wara DW, Cowan MJ, Barrett DJ, Stiehm ER -
Posttransfusion syndrome. Rash, eosinophilia, and thrombocytopenia following intrauterine and exchange transfusions.
American journal of diseases of children (1960) 1982 Chudwin DS, Ammann AJ, Wara DW, Cowan MJ, Phibbs RH -
Immunochemical studies on thymosin: radioimmunoassay of thymosin alpha 1.
Journal of immunology (Baltimore, Md. : 1950) 1982 McClure JE, Lameris N, Wara DW, Goldstein AL -
Use of intravenous gamma-globulin in antibody immunodeficiency: results of a multicenter controlled trial.
Clinical immunology and immunopathology 1982 Ammann AJ, Ashman RF, Buckley RH, Hardie WR, Krantmann HJ, Nelson J, Ochs H, Stiehm ER, Tiller T, Wara DW, Wedgwood R -
Clinical and immunologic spectrum of the DiGeorge syndrome.
Journal of clinical & laboratory immunology 1981 Barrett DJ, Ammann AJ, Wara DW, Cowan MJ, Fisher TJ, Stiehm ER -
Lung involvement in progressive vaccinia.
The Western journal of medicine 1981 Chudwin DS, Cowan MJ, Wara DW, Johnson AC -
Helper cell function of human fetal thymocytes.
Cellular immunology 1981 Barrett DJ, Stenmark S, Wara DW, Ammann AJ -
Host defense against Streptococcus pneumoniae: the role of the spleen.
Reviews of infectious diseases 1981 Wara DW -
Immunization of immunosuppressed patients with pneumococcal polysaccharide vaccine.
Reviews of infectious diseases 1981 Ammann AJ, Schiffman G, Addiego JE, Wara WM, Wara DW -
Role of lymphotoxin in antibody-dependent cell-mediated cytotoxicity (ADCC).
Journal of immunology (Baltimore, Md. : 1950) 1981 Kondo LL, Rosenau W, Wara DW -
Spectrum of Sjögren syndrome in children.
The Journal of pediatrics 1981 Chudwin DS, Daniels TE, Wara DW, Ammann AJ, Barrett DJ, Whitcher JP, Cowan MJ -
Effect of thymosin on cellular immunity in old age.
Mechanisms of ageing and development 1981 Cowan MJ, Fujiwara P, Wara DW, Ammann AJ -
Evaluation of the opsonic requirements for phagocytosis of Streptococcus pneumoniae serotypes VII, XIV, and XIX by chemiluminescence assay.
Infection and immunity 1981 Matthay KK, Mentzer WC, Wara DW, Preisler HK, Lameris NB, Ammann AJ -
Thymic hormones and the immune system.
Advances in pediatrics 1981 Wara DW -
Intermittent ataxia and immunodeficiency with multiple carboxylase deficiencies: a biotin-responsive disorder.
Annals of neurology 1980 Sander JE, Malamud N, Cowan MJ, Packman S, Amman AJ, Wara DW -
Immunoregulation in aged humans.
Clinical immunology and immunopathology 1980 Barrett DJ, Stenmark S, Wara DW, Ammann AJ -
Thymosin therapy in the DiGeorge syndrome.
The Journal of pediatrics 1980 Barrett DJ, Wara DW, Ammann AJ, Cowan MJ -
Immunoglobulin G and M antibodies to pneumococcal polysaccharides detected by enzyme-linked immunosorbent assay.
Infection and immunity 1980 Barrett DJ, Ammann AJ, Stenmark S, Wara DW -
The prevalence of autoantibodies in T-cell, B-cell, and phagocytic immunodeficiency disorders.
Clinical immunology and immunopathology 1979 Ammann AJ, Wara DW, Pillarisetty RJ, Talal N -
Cell-mediated immunity in the newborn: clinical aspects.
Pediatrics 1979 Wara DW, Barrett DJ -
Multiple biotin-dependent carboxylase deficiencies associated with defects in T-cell and B-cell immunity.
Lancet (London, England) 1979 Cowan MJ, Wara DW, Packman S, Ammann AJ, Yoshino M, Sweetman L, Nyhan W -
Immunosuppression and reconstitution with thymosin after radiation therapy.
International journal of radiation oncology, biology, physics 1979 Wara WM, Wara DW, Ammann AJ, Barnard JL, Phillips TL -
Milk precipitins in selective IgA deficiency.
Annals of allergy 1979 Barrett DJ, Bertani L, Wara DW, Ammann AJ -
In vitro and in vivo enhancement of mixed lymphocyte culture reactivity by thymosin in patients with primary immunodeficiency disease.
Annals of the New York Academy of Sciences 1979 Wara DW, Barrett DJ, Ammann AJ, Cowan MJ -
Effect of thymosin and irradiation on immune modulation in head and neck and esophageal cancer patients.
Cancer treatment reports 1978 Wara WM, Ammann AJ, Wara DW -
Pneumococcal polysaccharide immunization in infants and children.
Pediatrics 1978 Cowan MJ, Ammann AJ, Wara DW, Howie VM, Schultz L, Doyle N, Kaplan M -
Immunotherapy and immunopathologic studies in a patient with nucleoside phosphorylase deficiency.
Clinical immunology and immunopathology 1978 Ammann AJ, Wara DW, Allen T -
Thymosin treatment of children with primary immunodeficiency disease.
Transplantation proceedings 1978 Wara DW, Ammann AJ -
Familial nephrosis, hydrocephalus, thin skin, blue sclerae syndrome: clinical, structural and biochemical studies.
Birth defects original article series 1978 Daentl DL, Townsend JJ, Siegel RC, Godman JR, Piel CF, Wara DW, Bachmann RP -
Cellular immunodeficiency associated with nucleoside phosphorylase deficiency. Immunologic and biochemical studies.
Clinical immunology and immunopathology 1977 Sandman R, Ammann AJ, Grose C, Wara DW -
Immunologic competence in adults following thymic irradiation in infancy.
Radiology 1977 Ammann AJ, Wara WM, Wara DW, Phillips TL -
Laboratory diagnosis of immunodeficiency disease.
Pediatric clinics of North America 1977 Wara DW -
Immunity to Aspergillus in patients with chronic granulomatous disease.
The Journal of pediatrics 1977 Greenberg D, Ammann AJ, Wara DW, Kaltreider HB -
Autoantibody, autoimmune disease, and immunodeficiency.
Arthritis and rheumatism 1977 Ammann AJ, Wara DW, Pillarisetty RJ, Talal N -
Quantitation of B cells in peripheral blood by polyacrylamide beads coated with anti-human chain antibody.
Journal of immunological methods 1977 Ammann AJ, Borg D, Kondo L, Wara DW -
Editorial: Thymic cells and humoral factors as therapeutic agents.
Pediatrics 1976 Wara DW, Ammann AJ -
Thymus transplantation in patients with thymic hypoplasia and abnormal immunoglobulin synthesis.
Transplantation 1975 Ammann AJ, Wara DW, Doyle NE, Golbus MS -
Letter: Effect of thymosin on B-lymphocyte function.
The New England journal of medicine 1975 Wara DW, Ammann AJ -
Evaluation of infants and children with recurrent infection.
Current problems in pediatrics 1975 Ammann AJ, Wara DW -
Letter: Maternal-fetal graft vs host reaction.
The Journal of pediatrics 1975 Ammann AJ, Wara DW -
Serum IgA in the diagnosis of nasopharyngeal and paranasal sinus carcinoma.
Radiology 1975 Wara WM, Ammann AJ, Wara DW, Phillips TL -
Letter: Rosette-forming cells.
Lancet (London, England) 1975 Wara DW, Ammann AJ, Lipow HW, Diamond LK -
Nucleoside-phosphorylase deficiency in a child with severely defective T-cell immunity and normal B-cell immunity.
Lancet (London, England) 1975 Giblett ER, Ammann AJ, Wara DW, Sandman R, Diamond LK -
Elevated IGA in carcinoma of the nasopharynx.
Cancer 1975 Wara WM, Wara DW, Phillips TL, Ammann AJ -
Persistent Clq deficiency in a patient with a systemic lupus erythematosus-like syndrome.
The Journal of pediatrics 1975 Wara DW, Reiter EO, Doyle NE, Gewurz H, Ammann AJ -
Immunosuppression following radiation therapy for carcinoma of the nasopharynx.
The American journal of roentgenology, radium therapy, and nuclear medicine 1975 Wara WM, Phillips TL, Wara DW, Ammann AJ, Smith V -
Activation of T-cells rosettes in immunodeficient patients by thymosin.
Annals of the New York Academy of Sciences 1975 Wara DW, Ammann AJ -
Thymosin activity in patients with cellular immunodeficiency.
The New England journal of medicine 1975 Wara DW, Goldstein AL, Doyle NE, Ammann AJ -
Fetal thymus glands obtained from prostaglandin-induced abortions. Cellular immune function in vitro and evidence of in vivo thymocyte activity following transplantation.
Transplantation 1974 Wara DW, Golbus MS, Ammann AJ -
Transfer factor: therapy in patients with deficient cell-mediated immunity and deficient antibody-mediated immunity.
Cellular immunology 1974 Ammann AJ, Wara D, Salmon S -
Letter: T-cell rosettes in thyrotoxic Graves's disease.
The New England journal of medicine 1973 Wara DW, Reiter EO, Ammann AJ, Kaplan SL -
Thymus transplantation. Permanent reconstitution of cellular immunity in a patient with sex-linked combined immunodeficiency.
The New England journal of medicine 1973 Ammann AJ, Wara DW, Salmon S, Perkins H