Diana Alba, MD
Assistant Professor
Medicine
School of Medicine
Diana Alba is an Assistant Professor of Medicine in the Division of Endocrinology at the University of California San Francisco. She is board-certified by the American Board of Internal Medicine in the subspecialty of Endocrinology, Diabetes and Metabolism.
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Her primary research is focused on the pathogenesis of both obesity and diabetes in order to find ways to reduce deleterious metabolic outcomes in individuals from vulnerable populations. One of her projects addresses why individuals of certain ethnicities are prone to developing obesity-associated metabolic diseases despite having a relatively low group-level body mass index (BMI).
Awards
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- Early-Career Research Excellence Award in Basic/Translational Science, UCSF-Bay Area Center for AIDS Research, 2022
- Harold Amos Scholar, Robert Wood Johnson Foundation, 2020
- Minority Postdoctoral Fellowship Award, American Diabetes Association, 2018
Education & Training
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- Diversity, Equity, and Inclusion Champion Training University of California 2021
- Residency Internal Medicine University of Miami/Jackson Memorial Hospital 2013
- M.D. New York Medical College 2010
- Fellowship Endocrinology, Diabetes and Metabolism University of California
Websites
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- Inflammation, Diabetes, Ethnicity and Obesity (IDEO) Cohort (diabetes.ucsf.edu)
- UCSF Endocrine Clinical and Translational Research Center (ECTRC) (endocrine.ucsf.edu)
Grants and Projects
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- Dissecting the cellular interplays of adipose tissue remodeling in the regulation of insulin sensitivity, NIH/NIDDK
- Probing the cellular determinants of adipose tissue health versus fibrosis in the regulation of human insulin sensitivity, Robert Wood Johnson Foundation, Harold Amos Medical Faculty Development Program
- Assessing the Interrelationship Between Adipose Tissue Thermogenesis and Fibrosis in the Metabolic Health of People Living with HIV, NIH/NIDDK
Publications (19)
Top publication keywords:
Lipodystrophy, Congenital GeneralizedObesityReceptor, InsulinHand StrengthAnalgesics, OpioidMethadoneLipodystrophySubcutaneous Fat, AbdominalKidney Failure, ChronicGastric BypassHypoglycemiaInsulin ResistanceBody CompositionObesity, MorbidAdiposity
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PTP1B mediates the inhibitory effect of MFGE8 on insulin signaling through the β5 integrin.
The Journal of biological chemistry 2024 Datta R, Mukherjee D, Podolsky MJ, Yang CD, Alba DL, Singh S, Arnold TD, Koliwad S, Lizama CO, Atabai K -
Effects of Pharmacotherapy for the Treatment of Obesity in an Urban, Safety-Net Population.
Cureus 2023 Kim EK, Hills NK, Cheng Z, Tucker C, Gutierrez M, Alba D, Murphy E, Kim S -
MFGE8 inhibits insulin signaling through PTP1B.
bioRxiv : the preprint server for biology 2023 Datta R, Podolsky MJ, Yang CD, Alba DL, Singh S, Koliwad S, Lizama CO, Atabai K -
Autoantibodies to Perilipin-1 Define a Subset of Acquired Generalized Lipodystrophy.
Diabetes 2023 Mandel-Brehm C, Vazquez SE, Liverman C, Cheng M, Quandt Z, Kung AF, Parent A, Miao B, Disse E, Cugnet-Anceau C, Dalle S, Orlova E, Frolova E, Alba D, Michels A, Oftedal BE, Lionakis MS, Husebye ES, … -
A gene-diet interaction controlling relative intake of dietary carbohydrates and fats.
Molecular metabolism 2022 Nelson NG, Wu L, Maier MT, Lam D, Cheang R, Alba D, Huang A, Neumann DA, Hill T, Vagena E, Barsh GS, Medina MW, Krauss RM, Koliwad SK, Xu AW
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Probing Insulin Sensitivity with Metabolically Competent Human Stem Cell-Derived White Adipose Tissue Microphysiological Systems.
Small (Weinheim an der Bergstrasse, Germany) 2021 Qi L, Zushin PH, Chang CF, Lee YT, Alba DL, Koliwad SK, Stahl A -
The East Asian gut microbiome is distinct from colocalized White subjects and connected to metabolic health.
eLife 2021 Ang QY, Alba DL, Upadhyay V, Bisanz JE, Cai J, Lee HL, Barajas E, Wei G, Noecker C, Patterson AD, Koliwad SK, Turnbaugh PJ -
CD81 Controls Beige Fat Progenitor Cell Growth and Energy Balance via FAK Signaling.
Cell 2020 Oguri Y, Shinoda K, Kim H, Alba DL, Bolus WR, Wang Q, Brown Z, Pradhan RN, Tajima K, Yoneshiro T, Ikeda K, Chen Y, Cheang RT, Tsujino K, Kim CR, Greiner VJ, Datta R, Yang CD, Atabai K, McManus MT, … -
Genetic basis for the cooperative bioactivation of plant lignans by Eggerthella lenta and other human gut bacteria.
Nature microbiology 2019 Bess EN, Bisanz JE, Yarza F, Bustion A, Rich BE, Li X, Kitamura S, Waligurski E, Ang QY, Alba DL, Spanogiannopoulos P, Nayfach S, Koliwad SK, Wolan DW, Franke AA, Turnbaugh PJ -
Elastase 3B mutation links to familial pancreatitis with diabetes and pancreatic adenocarcinoma.
The Journal of clinical investigation 2019 Moore PC, Cortez JT, Chamberlain CE, Alba D, Berger AC, Quandt Z, Chan A, Cheng MH, Bautista JL, Peng J, German MS, Anderson MS, Oakes SA -
Obesity and Fat Metabolism in Human Immunodeficiency Virus-Infected Individuals: Immunopathogenic Mechanisms and Clinical Implications.
The Journal of infectious diseases 2019 Godfrey C, Bremer A, Alba D, Apovian C, Koethe JR, Koliwad S, Lewis D, Lo J, McComsey GA, Eckard A, Srinivasa S, Trevillyan J, Palmer C, Grinspoon S -
Sweet cognition: The differential effects of glucose consumption on attentional food bias in individuals of lean and obese status.
Physiology & behavior 2019 Mason AE, Jhaveri K, Schleicher S, Almeida C, Hartman A, Wackerly A, Alba D, Koliwad SK, Epel ES, Aschbacher K -
Changes in Lean Mass, Absolute and Relative Muscle Strength, and Physical Performance After Gastric Bypass Surgery.
The Journal of clinical endocrinology and metabolism 2019 Alba DL, Wu L, Cawthon PM, Mulligan K, Lang T, Patel S, King NJ, Carter JT, Rogers SJ, Posselt AM, Stewart L, Shoback DM, Schafer AL -
Methadone-Associated Hypoglycemia in Chronic Renal Failure Masquerading as an Insulinoma.
Pain medicine (Malden, Mass.) 2018 Masharani U, Alba D -
Subcutaneous Fat Fibrosis Links Obesity to Insulin Resistance in Chinese Americans.
The Journal of clinical endocrinology and metabolism 2018 Alba DL, Farooq JA, Lin MYC, Schafer AL, Shepherd J, Koliwad SK -
Repression of Adipose Tissue Fibrosis through a PRDM16-GTF2IRD1 Complex Improves Systemic Glucose Homeostasis.
Cell metabolism 2018 Hasegawa Y, Ikeda K, Chen Y, Alba DL, Stifler D, Shinoda K, Hosono T, Maretich P, Yang Y, Ishigaki Y, Chi J, Cohen P, Koliwad SK, Kajimura S -
Developmental staging of male murine embryonic gonad by SAGE analysis.
Journal of genetics and genomics = Yi chuan xue bao 2009 Lee TL, Li Y, Alba D, Vong QP, Wu SM, Baxendale V, Rennert OM, Lau YF, Chan WY -
Application of transcriptional and biological network analyses in mouse germ-cell transcriptomes.
Genomics 2006 Lee TL, Alba D, Baxendale V, Rennert OM, Chan WY -
Transcriptome analyses of male germ cells with serial analysis of gene expression (SAGE).
Molecular and cellular endocrinology 2006 Chan WY, Lee TL, Wu SM, Ruszczyk L, Alba D, Baxendale V, Rennert OM