Devan Diwanji, MD, PhD
RESIDENT
Radiology
School of Medicine

Publications (28)

Top publication keywords:
Neuregulin-1Protein MultimerizationReceptor, ErbB-2Receptor Protein-Tyrosine KinasesPositron Emission Tomography Computed TomographyRadiologyCryoelectron MicroscopyFluorodeoxyglucose F18Antibodies, NeutralizingDrug ResistanceReceptor, ErbB-3MicellesDetergentsBreast NeoplasmsProtein Conformation

• Comparative Uptake Patterns of Radioactive Iodine and [18F]-Fluorodeoxyglucose (FDG) in Metastatic Differentiated Thyroid Cancers.
  Journal of clinical medicine 2024 Diwanji D, Carrodeguas E, Seo Y, Kang H, Soe MH, Chiang JM, Zhang L, Liu C, Behr SC, Flavell RR
• Structural dynamics of the active HER4 and HER2/HER4 complexes is finely tuned by different growth factors and glycosylation.
  eLife 2024 Trenker R, Diwanji D, Bingham T, Verba KA, Jura N
• 18F-FDG Dedicated Breast PET Complementary to Breast MRI for Evaluating Early Response to Neoadjuvant Chemotherapy.
  Radiology. Imaging cancer 2024 Diwanji D, Onishi N, Hathi DK, Lawhn-Heath C, Kornak J, Li W, Guo R, Molina-Vega J, Seo Y, Flavell RR, Heditsian D, Brain S, Esserman LJ, Joe BN, Hylton NM, Jones EF, Ray KM
• Structural dynamics of the active HER4 and HER2/HER4 complexes is finely tuned by different growth factors and glycosylation.
  bioRxiv : the preprint server for biology 2024 Trenker R, Diwanji D, Bingham T, Verba KA, Jura N
• Structural insights into regulation of the PEAK3 pseudokinase scaffold by 14-3-3.
  Nature communications 2023 Torosyan H, Paul MD, Forget A, Lo M, Diwanji D, Pawlowski K, Krogan NJ, Jura N, Verba KA

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• Computational pipeline provides mechanistic understanding of Omicron variant of concern neutralizing engineered ACE2 receptor traps.
  Structure (London, England : 1993) 2023 Remesh SG, Merz GE, Brilot AF, Chio US, Rizo AN, Pospiech TH, Lui I, Laurie MT, Glasgow J, Le CQ, Zhang Y, Diwanji D, Hernandez E, Lopez J, Mehmood H, Pawar KI, Pourmal S, Smith AM, Zhou F, QCRG …
• Computational pipeline provides mechanistic understanding of Omicron variant of concern neutralizing engineered ACE2 receptor traps.
  bioRxiv : the preprint server for biology 2022 Remesh SG, Merz GE, Brilot AF, Chio US, Rizo AN, Pospiech TH, Lui I, Laurie MT, Glasgow J, Le CQ, Zhang Y, Diwanji D, Hernandez E, Lopez J, Pawar KI, Pourmal S, Smith AM, Zhou F, QCRG Structural …
• Brain Camp: A Summer Pipeline Program to Increase Diversity in Neurosciences.
  The neurologist 2022 Wei XP, Diwanji D, McHenry L, Lea R, McCluskey K, Griffin S, Comrie A, Margol V, Josephson SA
• An effective strategy for ligand-mediated pulldown of the HER2/HER3/NRG1β heterocomplex and cryo-EM structure determination at low sample concentrations.
  Methods in enzymology 2022 Trenker R, Diwanji D, Verba KA, Jura N
• Efficient expression, purification, and visualization by cryo-EM of unliganded near full-length HER3.
  Methods in enzymology 2022 Diwanji D, Trenker R, Jura N, Verba KA
• An Evidence-based and Inclusive Breast Cancer Screening Strategy: Summary of Current Guidelines from the American College of Radiology and Society of Breast Imaging.
  Radiology. Imaging cancer 2022 Diwanji D, Joe B
• Author Correction: Structures of the HER2-HER3-NRG1β complex reveal a dynamic dimer interface.
  Nature 2022 Diwanji D, Trenker R, Thaker TM, Wang F, Agard DA, Verba KA, Jura N
• Structures of the HER2-HER3-NRG1β complex reveal a dynamic dimer interface.
  Nature 2021 Diwanji D, Trenker R, Thaker TM, Wang F, Agard DA, Verba KA, Jura N
• 18F-FDG PET/CT Predicts Response to HER2-directed Neoadjuvant Therapy.
  Radiology. Imaging cancer 2021 Diwanji D, Ray K, Hylton N
• Mutant HER2 needs mutant HER3 to be an effective oncogene.
  Cell reports. Medicine 2021 Trenker R, Diwanji D, Jura N
• CryoEM and AI reveal a structure of SARS-CoV-2 Nsp2, a multifunctional protein involved in key host processes.
  Research square 2021 Gupta M, Azumaya CM, Moritz M, Pourmal S, Diallo A, Merz GE, Jang G, Bouhaddou M, Fossati A, Brilot AF, Diwanji D, Hernandez E, Herrera N, Kratochvil HT, Lam VL, Li F, Li Y, Nguyen HC, Nowotny C, …
• CryoEM and AI reveal a structure of SARS-CoV-2 Nsp2, a multifunctional protein involved in key host processes.
  bioRxiv : the preprint server for biology 2021 Gupta M, Azumaya CM, Moritz M, Pourmal S, Diallo A, Merz GE, Jang G, Bouhaddou M, Fossati A, Brilot AF, Diwanji D, Hernandez E, Herrera N, Kratochvil HT, Lam VL, Li F, Li Y, Nguyen HC, Nowotny C, …
• Sentinel cells enable genetic detection of SARS-CoV-2 Spike protein.
  bioRxiv : the preprint server for biology 2021 Weinberg ZY, Hilburger CE, Kim M, Cao L, Khalid M, Elmes S, Diwanji D, Hernandez E, Lopez J, Schaefer K, Smith AM, Zhou F, QCRG Structural Biology Consortium, Kumar GR, Ott M, Baker D, El-Samad H
• Human ACE2 receptor polymorphisms and altered susceptibility to SARS-CoV-2.
  Communications biology 2021 Suryamohan K, Diwanji D, Stawiski EW, Gupta R, Miersch S, Liu J, Chen C, Jiang YP, Fellouse FA, Sathirapongsasuti JF, Albers PK, Deepak T, Saberianfar R, Ratan A, Washburn G, Mis M, Santhosh D, …
• An ultrapotent synthetic nanobody neutralizes SARS-CoV-2 by stabilizing inactive Spike.
  Science (New York, N.Y.) 2020 Schoof M, Faust B, Saunders RA, Sangwan S, Rezelj V, Hoppe N, Boone M, Billesbølle CB, Puchades C, Azumaya CM, Kratochvil HT, Zimanyi M, Deshpande I, Liang J, Dickinson S, Nguyen HC, Chio CM, Merz GE,…
• Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.
  Science (New York, N.Y.) 2020 Gordon DE, Hiatt J, Bouhaddou M, Rezelj VV, Ulferts S, Braberg H, Jureka AS, Obernier K, Guo JZ, Batra J, Kaake RM, Weckstein AR, Owens TW, Gupta M, Pourmal S, Titus EW, Cakir M, Soucheray M, McGregor…
• An ultra-potent synthetic nanobody neutralizes SARS-CoV-2 by locking Spike into an inactive conformation.
  bioRxiv : the preprint server for biology 2020 Schoof M, Faust B, Saunders RA, Sangwan S, Rezelj V, Hoppe N, Boone M, Billesbølle CB, Puchades C, Azumaya CM, Kratochvil HT, Zimanyi M, Deshpande I, Liang J, Dickinson S, Nguyen HC, Chio CM, Merz GE,…
• More than the sum of the parts: Toward full-length receptor tyrosine kinase structures.
  IUBMB life 2019 Diwanji D, Thaker T, Jura N
• Structure of a cleavage-independent HIV Env recapitulates the glycoprotein architecture of the native cleaved trimer.
  Nature communications 2018 Sarkar A, Bale S, Behrens AJ, Kumar S, Sharma SK, de Val N, Pallesen J, Irimia A, Diwanji DC, Stanfield RL, Ward AB, Crispin M, Wyatt RT, Wilson IA
• Correction: Minimally Mutated HIV-1 Broadly Neutralizing Antibodies to Guide Reductionist Vaccine Design.
  PLoS pathogens 2016 Jardine JG, Sok D, Julien JP, Briney B, Sarkar A, Liang CH, Scherer EM, Henry Dunand CJ, Adachi Y, Diwanji D, Hsueh J, Jones M, Kalyuzhniy O, Kubitz M, Spencer S, Pauthner M, Saye-Francisco KL, …
• Minimally Mutated HIV-1 Broadly Neutralizing Antibodies to Guide Reductionist Vaccine Design.
  PLoS pathogens 2016 Jardine JG, Sok D, Julien JP, Briney B, Sarkar A, Liang CH, Scherer EA, Henry Dunand CJ, Adachi Y, Diwanji D, Hsueh J, Jones M, Kalyuzhniy O, Kubitz M, Spencer S, Pauthner M, Saye-Francisco KL, …
• Broadly neutralizing antibody PGT121 allosterically modulates CD4 binding via recognition of the HIV-1 gp120 V3 base and multiple surrounding glycans.
  PLoS pathogens 2013 Julien JP, Sok D, Khayat R, Lee JH, Doores KJ, Walker LM, Ramos A, Diwanji DC, Pejchal R, Cupo A, Katpally U, Depetris RS, Stanfield RL, McBride R, Marozsan AJ, Paulson JC, Sanders RW, Moore JP, …
• Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9.
  Nature 2011 McLellan JS, Pancera M, Carrico C, Gorman J, Julien JP, Khayat R, Louder R, Pejchal R, Sastry M, Dai K, O'Dell S, Patel N, Shahzad-ul-Hussan S, Yang Y, Zhang B, Zhou T, Zhu J, Boyington JC, Chuang GY,…