Debajyoti Datta, MD, PhD
Assistant Professor
Medicine
School of Medicine

Education & Training

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• Hematology/Oncology Fellowship University of California, San Francisco 06/2018
• Internal Medicine Residency Thomas Jefferson University Hospital 06/2015
• MD University of California, San Francisco 06/2012
• PhD Biophysics University of California, San Francisco 06/2010
• AB Physics Harvard University 06/2002

Publications (10)

Top publication keywords:
Caspase 3Allosteric SiteUltracentrifugationCaspasesAmino Acid Chloromethyl KetonesProtein AggregatesGene Expression Regulation, EnzymologicLewy Bodiesalpha-SynucleinDimerizationMolecular ConformationKineticsInflammasomesCaspase 1Biophysics

• ALK Inhibitor Treatment Patterns and Outcomes in Real-World Patients with ALK-Positive Non-Small-Cell Lung Cancer: A Retrospective Cohort Study.
  Targeted oncology 2023 Wang M, Slatter S, Sussell J, Lin CW, Ogale S, Datta D, Butte AJ, Bazhenova L, Rudrapatna VA
• PatientExploreR: an extensible application for dynamic visualization of patient clinical history from electronic health records in the OMOP common data model.
  Bioinformatics (Oxford, England) 2019 Glicksberg BS, Oskotsky B, Thangaraj PM, Giangreco N, Badgeley MA, Johnson KW, Datta D, Rudrapatna VA, Rappoport N, Shervey MM, Miotto R, Goldstein TC, Rutenberg E, Frazier R, Lee N, Israni S, Larsen …
• Abstract 1695: Linking clinical molecular profiles of tumors to the electronic medical record.
  Cancer Research 2019 Debajyoti Datta, Atul Butte, Theodore Goldstein
• Assessing real-world outcomes in precision oncology by linking clinical genomic testing to electronic medical records.
  Journal of Clinical Oncology 2019 Debajyoti Datta, Theodore Goldstein, Atul Butte
• ROMOP: a light-weight R package for interfacing with OMOP-formatted electronic health record data.
  JAMIA open 2019 Glicksberg BS, Oskotsky B, Giangreco N, Thangaraj PM, Rudrapatna V, Datta D, Frazier R, Lee N, Larsen R, Tatonetti NP, Butte AJ

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• Abstract LB-006: Oncology model fidelity scores.
  Bioinformatics and Systems Biology 2017 Debajyoti Datta, Theodore Goldstein, Zhiping Gu, Atul Butte
• Caspase-1 causes truncation and aggregation of the Parkinson's disease-associated protein α-synuclein.
  Proceedings of the National Academy of Sciences of the United States of America 2016 Wang W, Nguyen LT, Burlak C, Chegini F, Guo F, Chataway T, Ju S, Fisher OS, Miller DW, Datta D, Wu F, Wu CX, Landeru A, Wells JA, Cookson MR, Boxer MB, Thomas CJ, Gai WP, Ringe D, Petsko GA, Hoang QQ
• Substrate and inhibitor-induced dimerization and cooperativity in caspase-1 but not caspase-3.
  The Journal of biological chemistry 2013 Datta D, McClendon CL, Jacobson MP, Wells JA
• Abstract SY11-03: Turning enzymes on with small molecules.
  Cancer Chemistry 2010 James A. Wells, Dennis Wolan, Julie Zorn, Debajyoti Datta, Daniel Gray, Jack Sadowsky
• An allosteric circuit in caspase-1.
  Journal of molecular biology 2008 Datta D, Scheer JM, Romanowski MJ, Wells JA