David A. Kessler, MD
Professor
Pediatrics
School of Medicine

Grants and Projects

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• General Clinical Research Center, NIH, 1974-2009
• General Clinical Research Center, NIH, 1974-2007
• Pediatric Clinical Research Center, NIH, 1981-2007
• General Clinical Research Center, NIH, 1978-2006
• Tobacco Dependence and Risk Factors for Treatment Failur, NIH, 1999-2005
• General Clinical Research Center, NIH, 1989-2004
• UCSF ABSL-3 FACILITY, NIH, 2001-2004

Publications (57)

Top publication keywords:
Stochastic ProcessesModels, GeneticSelection, GeneticBiodiversityPopulation DensityBiological EvolutionEcosystemNamesPublic HealthComputer SimulationModels, BiologicalNutritive ValueEnvironmentPopulation DynamicsFood Labeling

• The dominant-egalitarian transition in species-rich communities.
  eLife 2025 Kessler DA, Shnerb NM
• Solutions of first-passage time problems: A biscaling approach.
  Physical review. E 2025 Baravi T, Kessler DA, Barkai E
• First Passage Times in Compact Domains Exhibit Biscaling.
  Physical review letters 2025 Baravi T, Kessler DA, Barkai E
• Interaction network structures in competitive ecosystems.
  Physical review. E 2025 Kessler DA, Shnerb NM
• Stretched-exponential relaxation in weakly confined Brownian systems through large deviation theory.
  Physical review. E 2024 Defaveri L, Barkai E, Kessler DA

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• Extinction time distributions of populations and genotypes.
  Physical review. E 2023 Kessler DA, Shnerb NM
• Non-normalizable quasiequilibrium states under fractional dynamics.
  Physical review. E 2023 Defaveri L, Dos Santos MAF, Kessler DA, Barkai E, Anteneodo C
• Brownian particles in periodic potentials: Coarse-graining versus fine structure.
  Physical review. E 2023 Defaveri L, Barkai E, Kessler DA
• Minimal frustration underlies the usefulness of incomplete regulatory network models in biology.
  Proceedings of the National Academy of Sciences of the United States of America 2022 Tripathi S, Kessler DA, Levine H
• Phenomenological Approach to Cancer Cell Persistence.
  Physical review letters 2022 Kessler DA, Levine H
• Discrete Sampling of Extreme Events Modifies Their Statistics.
  Physical review letters 2022 Zarfaty L, Barkai E, Kessler DA
• Ordered hexagonal patterns via notch-delta signaling.
  Physical biology 2021 Teomy E, Kessler DA, Levine H
• Non-Normalizable Quasi-Equilibrium Solution of the Fokker-Planck Equation for Nonconfining Fields.
  Entropy (Basel, Switzerland) 2021 Anteneodo C, Defaveri L, Barkai E, Kessler DA
• Saffman-Taylor fingers at intermediate noise.
  Physical review. E 2020 Shafir D, Kessler DA
• Biological Networks Regulating Cell Fate Choice Are Minimally Frustrated.
  Physical review letters 2020 Tripathi S, Kessler DA, Levine H
• From Non-Normalizable Boltzmann-Gibbs Statistics to Infinite-Ergodic Theory.
  Physical review letters 2019 Aghion E, Kessler DA, Barkai E
• Seven Former FDA Commissioners: The FDA Should Be An Independent Federal Agency.
  Health affairs (Project Hope) 2019 Califf RM, Hamburg M, Henney JE, Kessler DA, McClellan M, von Eschenbach AC, Young F
• Darwinian selection of host and bacteria supports emergence of Lamarckian-like adaptation of the system as a whole.
  Biology direct 2018 Osmanovic D, Kessler DA, Rabin Y, Soen Y
• Simulation of spatial systems with demographic noise.
  Physical review. E 2018 Weissmann H, Shnerb NM, Kessler DA
• Front propagation and clustering in the stochastic nonlocal Fisher equation.
  Physical review. E 2018 Ganan YA, Kessler DA
• First Detected Arrival of a Quantum Walker on an Infinite Line.
  Physical review letters 2018 Thiel F, Barkai E, Kessler DA
• Stability of two-species communities: Drift, environmental stochasticity, storage effect and selection.
  Theoretical population biology 2017 Danino M, Kessler DA, Shnerb NM
• Stochastic maps, continuous approximation, and stable distribution.
  Physical review. E 2017 Kessler DA, Burov S
• Effects of thymic selection on T cell recognition of foreign and tumor antigenic peptides.
  Proceedings of the National Academy of Sciences of the United States of America 2017 George JT, Kessler DA, Levine H
• Alternative steady states in ecological networks.
  Physical review. E 2017 Fried Y, Shnerb NM, Kessler DA
• Mechanical bounds to transcriptional noise.
  Proceedings of the National Academy of Sciences of the United States of America 2016 Sevier SA, Kessler DA, Levine H
• Communities as cliques.
  Scientific reports 2016 Fried Y, Kessler DA, Shnerb NM
• The effect of environmental stochasticity on species richness in neutral communities.
  Journal of theoretical biology 2016 Danino M, Shnerb NM, Azaele S, Kunin WE, Kessler DA
• Size distribution of ring polymers.
  Scientific reports 2016 Medalion S, Aghion E, Meirovitch H, Barkai E, Kessler DA
• Singularity screening in generic optical fields.
  Optics letters 2015 Freund I, Kessler DA, Vasyl'ev V, Soskin MS
• Emergence of structured communities through evolutionary dynamics.
  Journal of theoretical biology 2015 Shtilerman E, Kessler DA, Shnerb NM
• Scaling solution in the large population limit of the general asymmetric stochastic Luria-Delbrück evolution process.
  Journal of statistical physics 2014 Kessler DA, Levine H
• Resistance to chemotherapy: patient variability and cellular heterogeneity.
  Cancer research 2014 Kessler DA, Austin RH, Levine H
• Toward more comprehensive food labeling.
  The New England journal of medicine 2014 Kessler DA
• Temporal fluctuation scaling in populations and communities.
  Ecology 2014 Kalyuzhny M, Schreiber Y, Chocron R, Flather CH, Kadmon R, Kessler DA, Shnerb NM
• Growth feedback as a basis for persister bistability.
  Proceedings of the National Academy of Sciences of the United States of America 2013 Feng J, Kessler DA, Ben-Jacob E, Levine H
• Neutral-like abundance distributions in the presence of selection in a continuous fitness landscape.
  Journal of theoretical biology 2013 Kessler DA, Shnerb NM
• Large population solution of the stochastic Luria-Delbruck evolution model.
  Proceedings of the National Academy of Sciences of the United States of America 2013 Kessler DA, Levine H
• Model for macroevolutionary dynamics.
  Proceedings of the National Academy of Sciences of the United States of America 2013 Maruvka YE, Shnerb NM, Kessler DA, Ricklefs RE
• Coexistence in an inhomogeneous environment.
  PloS one 2013 Weisman S, Kessler DA
• A tribute to C. Everett Koop.
  Proceedings of the National Academy of Sciences of the United States of America 2013 Kessler DA, Nesbit JA, Westmoreland TM, Albright MB
• You name it--memory and delay govern first name dynamics.
  PloS one 2012 Kessler DA, Maruvka YE, Ouren J, Shnerb NM
• The birth-death-mutation process: a new paradigm for fat tailed distributions.
  PloS one 2011 Maruvka YE, Kessler DA, Shnerb NM
• Effect of spontaneous twist on DNA minicircles.
  Biophysical journal 2010 Medalion S, Kessler DA, Rabin Y
• Optimal strategy for competence differentiation in bacteria.
  PLoS genetics 2010 Wylie CS, Trout AD, Kessler DA, Levine H
• Universal features of surname distribution in a subsample of a growing population.
  Journal of theoretical biology 2009 Maruvka YE, Shnerb NM, Kessler DA
• Singularities in speckled speckle: screening.
  Journal of the Optical Society of America. A, Optics, image science, and vision 2008 Kessler DA, Freund I
• Singularities in speckled speckle.
  Optics letters 2008 Freund I, Kessler DA
• Deconstructing the vanilla milkshake: the dominant effect of sucrose on self-administration of nutrient-flavor mixtures.
  Appetite 2007 Naleid AM, Grimm JW, Kessler DA, Sipols AJ, Aliakbari S, Bennett JL, Wells J, Figlewicz DP
• Direct-to-consumer advertising: is it too late to manage the risks?
  Annals of family medicine 2007 Kessler DA, Levy DA
• FDA regulation of stem-cell-based therapies.
  The New England journal of medicine 2006 Halme DG, Kessler DA
• Directional sensing in eukaryotic chemotaxis: a balanced inactivation model.
  Proceedings of the National Academy of Sciences of the United States of America 2006 Levine H, Kessler DA, Rappel WJ
• Alcohol marketing and youth: the challenge for public health.
  Journal of public health policy 2005 Kessler DA
• Equilibrium state of molecular breeding.
  Journal of mathematical biology 2005 Cohen E, Kessler DA
• Mesenchymoma: an unusual tumour of the lip.
  The British journal of oral & maxillofacial surgery 2004 Kessler DA, Kademani D, Feldman RS, Howlett P
• Distribution functions for filaments under tension.
  The Journal of chemical physics 2004 Kessler DA, Rabin Y
• Lissajous singularities.
  Optics letters 2003 Kessler DA, Freund I