David Solomon, MD, PhD
Assistant Professor
Pathology
School of Medicine

The cohesin complex is responsible for sister chromatid cohesion following DNA replication and helps ensure faithful chromosome segregation during mitosis, but has also been implicated in additional cellular processes such as regulation of chromatin architecture and gene transcription. Using a newly generated conditional STAG2 knockout mouse and isogenic sets of STAG2 proficient and deficient human cell lines, we are currently working to determine the function of STAG2 during development and tumorigenesis and to identify therapeutic vulnerabilities in the many cancers harboring cohesin gene alterations. Other ongoing studies in the Solomon Lab include functional genomics and epigenomics evaluation of the many different brain tumor subtypes including glioblastoma, low-grade glioneuronal tumors, and meningioma.

• Whole tumor analysis reveals early origin of the TERT promoter mutation and intercellular heterogeneity in TERT expression.
  Neuro-oncology 2024 Appin CL, Hong C, Suwala AK, Hilz S, Mathur R, Solomon DA, Smirnov IV, Stevers NO, Shai A, Wang A, Berger MS, Chang SM, Phillips JJ, Costello JF
• Glioblastoma evolution and heterogeneity from a 3D whole-tumor perspective.
  Cell 2024 Mathur R, Wang Q, Schupp PG, Nikolic A, Hilz S, Hong C, Grishanina NR, Kwok D, Stevers NO, Jin Q, Youngblood MW, Stasiak LA, Hou Y, Wang J, Yamaguchi TN, Lafontaine M, Shai A, Smirnov IV, Solomon DA, …
• "De novo replication repair deficient glioblastoma, IDH-wildtype" is a distinct glioblastoma subtype in adults that may benefit from immune checkpoint blockade.
  Acta neuropathologica 2023 Hadad S, Gupta R, Oberheim Bush NA, Taylor JW, Villanueva-Meyer JE, Young JS, Wu J, Ravindranathan A, Zhang Y, Warrier G, McCoy L, Shai A, Pekmezci M, Perry A, Bollen AW, Phillips JJ, Braunstein SE, …
• Novel SOX10 indel mutations drive schwannomas through impaired transactivation of myelination gene programs.
  Neuro-oncology 2023 Williams EA, Ravindranathan A, Gupta R, Stevers NO, Suwala AK, Hong C, Kim S, Yuan JB, Wu J, Barreto J, Lucas CG, Chan E, Pekmezci M, LeBoit PE, Mully T, Perry A, Bollen A, Van Ziffle J, Devine WP, …
• Everolimus for Children With Recurrent or Progressive Low-Grade Glioma: Results From the Phase II PNOC001 Trial.
  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2023 Haas-Kogan DA, Aboian MS, Minturn JE, Leary SES, Abdelbaki MS, Goldman S, Elster JD, Kraya A, Lueder MR, Ramakrishnan D, von Reppert M, Liu KX, Rokita JL, Resnick AC, Solomon DA, Phillips JJ, Prados M…
• Targeted gene expression profiling predicts meningioma outcomes and radiotherapy responses.
  Nature medicine 2023 Chen WC, Choudhury A, Youngblood MW, Polley MC, Lucas CG, Mirchia K, Maas SLN, Suwala AK, Won M, Bayley JC, Harmanci AS, Harmanci AO, Klisch TJ, Nguyen MP, Vasudevan HN, McCortney K, Yu TJ, Bhave V, …
• Clinical, genomic, and epigenomic analyses of H3K27M-mutant diffuse midline glioma long-term survivors reveal a distinct group of tumors with MAPK pathway alterations.
  Acta neuropathologica 2023 Roberts HJ, Ji S, Picca A, Sanson M, Garcia M, Snuderl M, Schüller U, Picart T, Ducray F, Green AL, Nakano Y, Sturm D, Abdullaev Z, Aldape K, Dang D, Kumar-Sinha C, Wu YM, Robinson D, Vo JN, …
• Somatic mosaic SOX10 indel mutations underlie a form of segmental schwannomatosis.
  Acta neuropathologica 2023 Terry M, Gupta R, Ravindranathan A, Wu J, Chan E, Bollen AW, Chang SM, Berger MS, Jacques L, Solomon DA
• Quantitative analysis of MGMT promoter methylation in glioblastoma suggests nonlinear prognostic effect.
  Neuro-oncology advances 2023 Gibson D, Ravi A, Rodriguez E, Chang S, Oberheim Bush N, Taylor J, Clarke J, Solomon D, Scheffler A, Witte J, Lambing H, Okada H, Berger M, Chehab F, Butowski NA
• Molecular profiling identifies at least 3 distinct types of posttransplant lymphoproliferative disorder involving the CNS.
  Blood advances 2023 Guney E, Lucas CG, Singh K, Pekmezci M, Fernandez-Pol S, Mirchia K, Toland A, Vogel H, Bannykh S, Schafernak KT, Alexandrescu S, Mobley BC, Powell S, Davidson CJ, Neltner J, Boué DR, Hattab E, Ferris …
• Loss of p16 expression is a sensitive marker of CDKN2A homozygous deletion in malignant meningiomas.
  Acta neuropathologica 2023 Tang V, Lu R, Mirchia K, Van Ziffle J, Devine P, Lee J, Phillips JJ, Perry A, Raleigh DR, Lucas CG, Solomon DA
• A single-cell atlas of glioblastoma evolution under therapy reveals cell-intrinsic and cell-extrinsic therapeutic targets.
  Nature cancer 2022 Wang L, Jung J, Babikir H, Shamardani K, Jain S, Feng X, Gupta N, Rosi S, Chang S, Raleigh D, Solomon D, Phillips JJ, Diaz AA
• EANO - EURACAN - SNO Guidelines on circumscribed astrocytic gliomas, glioneuronal, and neuronal tumors.
  Neuro-oncology 2022 Rudà R, Capper D, Waldman AD, Pallud J, Minniti G, Kaley TJ, Bouffet E, Tabatabai G, Aronica E, Jakola AS, Pfister SM, Schiff D, Lassman AB, Solomon DA, Soffietti R, Weller M, Preusser M, Idbaih A, …
• Amplification of the PLAG-family genes-PLAGL1 and PLAGL2-is a key feature of the novel tumor type CNS embryonal tumor with PLAGL amplification.
  Acta neuropathologica 2022 Keck MK, Sill M, Wittmann A, Joshi P, Stichel D, Beck P, Okonechnikow K, Sievers P, Wefers AK, Roncaroli F, Avula S, McCabe MG, Hayden JT, Wesseling P, Øra I, Nistér M, Kranendonk MEG, Tops BBJ, …
• Patterns of Extraneural Metastases in Children With Ependymoma.
  Journal of pediatric hematology/oncology 2022 Chan PP, Whipple NS, Ramani B, Solomon DA, Zhou H, Linscott LL, Kestle JRW, Bruggers CS
• Expanded analysis of high-grade astrocytoma with piloid features identifies an epigenetically and clinically distinct subtype associated with neurofibromatosis type 1.
  Acta neuropathologica 2022 Cimino PJ, Ketchum C, Turakulov R, Singh O, Abdullaev Z, Giannini C, Pytel P, Lopez GY, Colman H, Nasrallah MP, Santi M, Fernandes IL, Nirschl J, Dahiya S, Neill S, Solomon D, Perez E, Capper D, Mani …
• Prospective genomically guided identification of "early/evolving" and "undersampled" IDH-wildtype glioblastoma leads to improved clinical outcomes.
  Neuro-oncology 2022 Zhang Y, Lucas CG, Young JS, Morshed RA, McCoy L, Oberheim Bush NA, Taylor JW, Daras M, Butowski NA, Villanueva-Meyer JE, Cha S, Wrensch M, Wiencke JK, Lee JC, Pekmezci M, Phillips JJ, Perry A, Bollen…
• Conserved features of TERT promoter duplications reveal an activation mechanism that mimics hotspot mutations in cancer.
  Nature communications 2022 Barger CJ, Suwala AK, Soczek KM, Wang AS, Kim MY, Hong C, Doudna JA, Chang SM, Phillips JJ, Solomon DA, Costello JF
• PI3K/AKT/mTOR signaling pathway activity in IDH-mutant diffuse glioma and clinical implications.
  Neuro-oncology 2022 Mohamed E, Kumar A, Zhang Y, Wang AS, Chen K, Lim Y, Shai A, Taylor JW, Clarke J, Hilz S, Berger MS, Solomon DA, Costello JF, Molinaro AM, Phillips JJ
• Multiplatform molecular analyses refine classification of gliomas arising in patients with neurofibromatosis type 1.
  Acta neuropathologica 2022 Lucas CG, Sloan EA, Gupta R, Wu J, Pratt D, Vasudevan HN, Ravindranathan A, Barreto J, Williams EA, Shai A, Whipple NS, Bruggers CS, Maher O, Nabors B, Rodriguez M, Samuel D, Brown M, Carmichael J, Lu…
• Targeted Next-Generation Sequencing Reveals Divergent Clonal Evolution in Components of Composite Pleomorphic Xanthoastrocytoma-Ganglioglioma.
  Journal of neuropathology and experimental neurology 2022 Lucas CG, Davidson CJ, Alashari M, Putnam AR, Whipple NS, Bruggers CS, Mendez JS, Cheshier SH, Walker JB, Ramani B, Cadwell CR, Sullivan DV, Lu R, Mirchia K, Van Ziffle J, Devine P, Goldschmidt E, …
• Iris and Ciliary Body Melanocytomas Are Defined by Solitary GNAQ Mutation Without Additional Oncogenic Alterations.
  Ophthalmology 2022 Solomon DA, Ramani B, Eiger-Moscovich M, Milman T, Uludag G, Crawford JB, Phan I, Char DH, Shields CL, Eagle RC, Bastian BC, Bloomer MM, Pekmezci M
• CXCL14 Promotes a Robust Brain Tumor-Associated Immune Response in Glioma.
  Clinical cancer research : an official journal of the American Association for Cancer Research 2022 Kumar A, Mohamed E, Tong S, Chen K, Mukherjee J, Lim Y, Wong CM, Boosalis Z, Shai A, Pieper RO, Gupta N, Perry A, Bollen AW, Molinaro AM, Solomon DA, Shieh JTC, Phillips JJ
• Intratumor and informatic heterogeneity influence meningioma molecular classification.
  Acta neuropathologica 2022 Vasudevan HN, Choudhury A, Hilz S, Villanueva-Meyer JE, Chen WC, Lucas CG, Braunstein SE, Oberheim Bush NA, Butowski N, Pekmezci M, McDermott MW, Perry A, Solomon DA, Magill ST, Raleigh DR
• A genetically distinct pediatric subtype of primary CNS large B-cell lymphoma is associated with favorable clinical outcome.
  Blood advances 2022 Güney E, Lucas CG, Qi Z, Yu J, Zhang R, Ohgami RS, Rubenstein JL, Boué DR, Schafernak K, Wertheim GB, Dahiya S, Giulino-Roth L, Attarbaschi A, Barth MJ, Kothari S, Abla O, Cohen AL, Mendez JS, Bollen …
• Recurrent ACVR1 mutations in posterior fossa ependymoma.
  Acta neuropathologica 2022 Pratt D, Lucas CG, Selvam PP, Abdullaev Z, Ketchum C, Quezado M, Armstrong TS, Gilbert MR, Papanicolau-Sengos A, Raffeld M, Choo-Wosoba H, Chan P, Whipple N, Nasrallah M, Santi M, Ramaswamy V, …
• Meningioma DNA methylation groups identify biological drivers and therapeutic vulnerabilities.
  Nature genetics 2022 Choudhury A, Magill ST, Eaton CD, Prager BC, Chen WC, Cady MA, Seo K, Lucas CG, Casey-Clyde TJ, Vasudevan HN, Liu SJ, Villanueva-Meyer JE, Lam TC, Pu JK, Li LF, Leung GK, Swaney DL, Zhang MY, Chan JW,…
• Combining radiomics and deep convolutional neural network features from preoperative MRI for predicting clinically relevant genetic biomarkers in glioblastoma.
  Neuro-oncology advances 2022 Calabrese E, Rudie JD, Rauschecker AM, Villanueva-Meyer JE, Clarke JL, Solomon DA, Cha S
• High-grade glioma with pleomorphic and pseudopapillary features (HPAP): a proposed type of circumscribed glioma in adults harboring frequent TP53 mutations and recurrent monosomy 13.
  Acta neuropathologica 2022 Pratt D, Abdullaev Z, Papanicolau-Sengos A, Ketchum C, Panneer Selvam P, Chung HJ, Lee I, Raffeld M, Gilbert MR, Armstrong TS, Pytel P, Borys E, Klonoski JM, McCord M, Horbinski C, Brat D, Perry A, …
• Activating NTRK2 and ALK receptor tyrosine kinase fusions extend the molecular spectrum of pleomorphic xanthoastrocytomas of early childhood: a diagnostic overlap with infant-type hemispheric glioma.
  Acta neuropathologica 2021 Lucas CG, Abdullaev Z, Bruggers CS, Mirchia K, Whipple NS, Alashari MM, Lowichik A, Cheshier S, Phillips JJ, Devine P, Solomon DA, Quezado M, Aldape KD, Perry A
• EWSR1-BEND2 fusion defines an epigenetically distinct subtype of astroblastoma.
  Acta neuropathologica 2021 Lucas CG, Gupta R, Wu J, Shah K, Ravindranathan A, Barreto J, Gener M, Ginn KF, Prall OWJ, Xu H, Kee D, Ko HS, Yaqoob N, Zia N, Florez A, Cha S, Perry A, Clarke JL, Chang SM, Berger MS, Solomon DA
• Intracranial mesenchymal tumors with FET-CREB fusion are composed of at least two epigenetic subgroups distinct from meningioma and extracranial sarcomas.
  Brain pathology (Zurich, Switzerland) 2021 Sloan EA, Gupta R, Koelsche C, Chiang J, Villanueva-Meyer JE, Alexandrescu S, Eschbacher JM, Wang W, Mafra M, Ud Din N, Carr-Boyd E, Watson M, Punsoni M, Oviedo A, Gilani A, Kleinschmidt-DeMasters BK,…
• Diffuse hemispheric glioma, H3 G34-mutant: Genomic landscape of a new tumor entity and prospects for targeted therapy.
  Neuro-oncology 2021 Lucas CG, Mueller S, Reddy A, Taylor JW, Oberheim Bush NA, Clarke JL, Chang SM, Gupta N, Berger MS, Perry A, Phillips JJ, Solomon DA
• Temozolomide-induced hypermutation is associated with distant recurrence and reduced survival after high-grade transformation of low-grade IDH-mutant gliomas.
  Neuro-oncology 2021 Yu Y, Villanueva-Meyer J, Grimmer MR, Hilz S, Solomon DA, Choi S, Wahl M, Mazor T, Hong C, Shai A, Phillips JJ, Wainer BH, McDermott M, Haas-Kogan D, Taylor JW, Butowski N, Clarke JL, Berger MS, …
• Genetic and epigenetic characterization of posterior pituitary tumors.
  Acta neuropathologica 2021 Schmid S, Solomon DA, Perez E, Thieme A, Kleinschmidt-DeMasters BK, Giannini C, Reinhardt A, Asa SL, Mete O, Stichel D, Siewert C, Dittmayer C, Hasselblatt M, Paulus W, Nagel C, Harter PN, …
• Adjuvant Maintenance Larotrectinib Therapy in 2 Children With NTRK Fusion-positive High-grade Cancers.
  Journal of pediatric hematology/oncology 2021 Carter-Febres M, Schneller N, Fair D, Solomon D, Perry A, Roy A, Linscott L, Alashari M, Kestle JR, Bruggers CS
• Systemic and Craniospinal Rosai Dorfman Disease with Intraparenchymal, Intramedullary and Leptomeningeal Disease.
  International journal of hematology-oncology and stem cell research 2021 Li Y, Sloan E, Bollen A, Solomon D, Theodosopoulos P, Cha S
• Tumor DNA requirements for accurate epigenetic-based classification of CNS neoplasia.
  Neuro-oncology 2021 Wu J, Gupta R, Barreto J, Doo P, Joseph NM, Lee JC, Perry A, Chang SM, Berger MS, Solomon DA
• Sarcomatous Meningioma: Diagnostic Pitfalls and the Utility of Molecular Testing.
  Journal of neuropathology and experimental neurology 2021 Lucas CG, Devine P, Solomon DA, Giannini C, Reifenberger G, Dahiya S, Caccamo D, Perry A
• Deconvoluting Mechanisms of Acquired Resistance to RAF Inhibitors in BRAFV600E-Mutant Human Glioma.
  Clinical cancer research : an official journal of the American Association for Cancer Research 2021 Schreck KC, Morin A, Zhao G, Allen AN, Flannery P, Glantz M, Green AL, Jones C, Jones KL, Kilburn LB, Nazemi KJ, Samuel D, Sanford B, Solomon DA, Wang J, Pratilas CA, Nicolaides T, Mulcahy Levy JM
• A multicenter analysis of the prognostic value of histone H3 K27M mutation in adult high-grade spinal glioma.
  Journal of neurosurgery. Spine 2021 Akinduro OO, Garcia DP, Higgins DMO, Vivas-Buitrago T, Jentoft M, Solomon DA, Daniels DJ, Pennington Z, Sherman WJ, Delgardo M, Bydon M, Kalani MA, Zanazzi G, Tsankova N, Bendok BR, McCormick PC, …
• Low-grade glioneuronal tumors with FGFR2 fusion resolve into a single epigenetic group corresponding to 'Polymorphous low-grade neuroepithelial tumor of the young'.
  Acta neuropathologica 2021 Gupta R, Lucas CG, Wu J, Barreto J, Shah K, Simon IB, Casavilca-Zambrano S, Brathwaite C, Zhou H, Caccamo D, Gilani A, Kleinschmidt-DeMasters BK, Lee JC, Perry A, Clarke JL, Chang SM, Berger MS, …
• Molecular characterisation of sporadic endolymphatic sac tumours and comparison to von Hippel-Lindau disease-related tumours.
  Neuropathology and applied neurobiology 2021 Schweizer L, Thierfelder F, Thomas C, Soschinski P, Kim HY, Jödicke R, Woltering N, Förster A, Teichmann D, Siewert C, Klein K, Schmid S, Nunninger M, Thomale UW, Onken J, Mühleisen H, Schittenhelm J,…
• Letter: Patterns of Intermediate- and High-Risk Meningioma Recurrence After Treatment With Postoperative External Beam Radiotherapy.
  Neurosurgery 2021 Susko MS, Chen WC, Vasudevan HN, Magill ST, Lucas CG, Oberheim Bush NA, Solomon DA, Theodosopoulos PV, McDermott MW, Villanueva-Meyer JE, Boreta L, Nakamura JL, Sneed PK, Braunstein SE, Raleigh DR
• A subset of pediatric-type thalamic gliomas share a distinct DNA methylation profile, H3K27me3 loss and frequent alteration of EGFR.
  Neuro-oncology 2021 Sievers P, Sill M, Schrimpf D, Stichel D, Reuss DE, Sturm D, Hench J, Frank S, Krskova L, Vicha A, Zapotocky M, Bison B, Castel D, Grill J, Debily MA, Harter PN, Snuderl M, Kramm CM, Reifenberger G, …
• Intracranial mesenchymal tumor with FET-CREB fusion-A unifying diagnosis for the spectrum of intracranial myxoid mesenchymal tumors and angiomatoid fibrous histiocytoma-like neoplasms.
  Brain pathology (Zurich, Switzerland) 2021 Sloan EA, Chiang J, Villanueva-Meyer JE, Alexandrescu S, Eschbacher JM, Wang W, Mafra M, Ud Din N, Carr-Boyd E, Watson M, Punsoni M, Oviedo A, Gilani A, Kleinschmidt-DeMasters BK, Coss DJ, Lopes MB, …
• Eye-sparing Treatment of Localized Orbital Medulloepithelioma With Neoadjuvant Chemoradiation.
  Ophthalmic plastic and reconstructive surgery 2021 Gallo RA, Shoag J, Johnson TE, Solomon DA, Perry A, Podda A, Lee JY, Rong AJ
• A Prognostic Gene-Expression Signature and Risk Score for Meningioma Recurrence After Resection.
  Neurosurgery 2020 Chen WC, Vasudevan HN, Choudhury A, Pekmezci M, Lucas CG, Phillips J, Magill ST, Susko MS, Braunstein SE, Oberheim Bush NA, Boreta L, Nakamura JL, Villanueva-Meyer JE, Sneed PK, Perry A, McDermott MW,…
• Clinical, radiologic, and genetic characteristics of histone H3 K27M-mutant diffuse midline gliomas in adults.
  Neuro-oncology advances 2020 Schulte JD, Buerki RA, Lapointe S, Molinaro AM, Zhang Y, Villanueva-Meyer JE, Perry A, Phillips JJ, Tihan T, Bollen AW, Pekmezci M, Butowski N, Oberheim Bush NA, Taylor JW, Chang SM, Theodosopoulos P,…
• The immunohistochemical, DNA methylation, and chromosomal copy number profile of cauda equina paraganglioma is distinct from extra-spinal paraganglioma.
  Acta neuropathologica 2020 Ramani B, Gupta R, Wu J, Barreto J, Bollen AW, Tihan T, Mummaneni PV, Ames C, Clark A, Oberheim Bush NA, Butowski N, Phillips D, King BE, Bator SM, Treynor EC, Zherebitskiy V, Quinn PS, Walker JB, …
• Comprehensive analysis of diverse low-grade neuroepithelial tumors with FGFR1 alterations reveals a distinct molecular signature of rosette-forming glioneuronal tumor.
  Acta neuropathologica communications 2020 Lucas CG, Gupta R, Doo P, Lee JC, Cadwell CR, Ramani B, Hofmann JW, Sloan EA, Kleinschmidt-DeMasters BK, Lee HS, Wood MD, Grafe M, Born D, Vogel H, Salamat S, Puccetti D, Scharnhorst D, Samuel D, …
• A novel PARD3B-NUTM1 fusion in an aggressive primary CNS embryonal tumor in a young adult.
  Acta neuropathologica communications 2020 Ko K, Kitani T, Harris BT, Anaizi AN, Solomon D, Perry A, Toretsky J, Ozdemirli M
• DNA methylation profiling demonstrates superior diagnostic classification to RNA-sequencing in a case of metastatic meningioma.
  Acta neuropathologica communications 2020 Vasudevan HN, Castro MRH, Lee JC, Villanueva-Meyer JE, Bush NAO, McDermott MW, Solomon DA, Perry A, Magill ST, Raleigh DR
• cIMPACT-NOW update 6: new entity and diagnostic principle recommendations of the cIMPACT-Utrecht meeting on future CNS tumor classification and grading.
  Brain pathology (Zurich, Switzerland) 2020 Louis DN, Wesseling P, Aldape K, Brat DJ, Capper D, Cree IA, Eberhart C, Figarella-Branger D, Fouladi M, Fuller GN, Giannini C, Haberler C, Hawkins C, Komori T, Kros JM, Ng HK, Orr BA, Park SH, Paulus…
• Infant High-Grade Gliomas Comprise Multiple Subgroups Characterized by Novel Targetable Gene Fusions and Favorable Outcomes.
  Cancer discovery 2020 Clarke M, Mackay A, Ismer B, Pickles JC, Tatevossian RG, Newman S, Bale TA, Stoler I, Izquierdo E, Temelso S, Carvalho DM, Molinari V, Burford A, Howell L, Virasami A, Fairchild AR, Avery A, Chalker J…
• Catastrophic stroke burden in a patient with uncontrolled psoriasis and psoriatic arthritis: a case report.
  BMC neurology 2020 Fan JM, Solomon DA, López GY, Hofmann JW, Colorado RA, Kim AS, Meisel K, Halabi C
• Gliomas arising in the setting of Li-Fraumeni syndrome stratify into two molecular subgroups with divergent clinicopathologic features.
  Acta neuropathologica 2020 Sloan EA, Hilz S, Gupta R, Cadwell C, Ramani B, Hofmann J, Kline CN, Banerjee A, Reddy A, Oberheim Bush NA, Chang S, Braunstein S, Chang EF, Raffel C, Gupta N, Sun PP, Kim JYH, Moes G, Alva E, Li R, …
• An update on the central nervous system manifestations of familial tumor predisposition syndromes.
  Acta neuropathologica 2020 Solomon DA
• Loss of H3K27 trimethylation by immunohistochemistry is frequent in oligodendroglioma, IDH-mutant and 1p/19q-codeleted, but is neither a sensitive nor a specific marker.
  Acta neuropathologica 2020 Pekmezci M, Phillips JJ, Dirilenoglu F, Atasever-Rezanko T, Tihan T, Solomon D, Bollen A, Perry A
• Multiregion exome sequencing of ovarian immature teratomas reveals 2N near-diploid genomes, paucity of somatic mutations, and extensive allelic imbalances shared across mature, immature, and disseminated components.
  Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2020 Heskett MB, Sanborn JZ, Boniface C, Goode B, Chapman J, Garg K, Rabban JT, Zaloudek C, Benz SC, Spellman PT, Solomon DA, Cho RJ
• Pathology of meningiomas.
  Handbook of clinical neurology 2020 Solomon DA, Pekmezci M
• Clinicopathologic and molecular features of intracranial desmoplastic small round cell tumors.
  Brain pathology (Zurich, Switzerland) 2019 Lee JC, Villanueva-Meyer JE, Ferris SP, Cham EM, Zucker J, Cooney T, Gilani A, Kleinschmidt-DeMasters BK, Trembath D, Mafra M, Chiang J, Ellison DW, Cho SJ, Horvai AE, Van Ziffle J, Onodera C, Devine …
• Next-Generation Sequencing of Retinoblastoma Identifies Pathogenic Alterations beyond RB1 Inactivation That Correlate with Aggressive Histopathologic Features.
  Ophthalmology 2019 Afshar AR, Pekmezci M, Bloomer MM, Cadenas NJ, Stevers M, Banerjee A, Roy R, Olshen AB, Van Ziffle J, Onodera C, Devine WP, Grenert JP, Bastian BC, Solomon DA, Damato BE
• Diffusion Characteristics of Pediatric Diffuse Midline Gliomas with Histone H3-K27M Mutation Using Apparent Diffusion Coefficient Histogram Analysis.
  AJNR. American journal of neuroradiology 2019 Aboian MS, Tong E, Solomon DA, Kline C, Gautam A, Vardapetyan A, Tamrazi B, Li Y, Jordan CD, Felton E, Weinberg B, Braunstein S, Mueller S, Cha S
• Myxoid glioneuronal tumor, PDGFRA p.K385-mutant: clinical, radiologic, and histopathologic features.
  Brain pathology (Zurich, Switzerland) 2019 Lucas CG, Villanueva-Meyer JE, Whipple N, Oberheim Bush NA, Cooney T, Chang S, McDermott M, Berger M, Cham E, Sun PP, Putnam A, Zhou H, Bollo R, Cheshier S, Poppe MM, Fung KM, Sung S, Glenn C, Fan X, …
• A review of recently described genetic alterations in central nervous system tumors.
  Human pathology 2019 Lucas CG, Solomon DA, Perry A
• Neuroglial stem cell-derived inflammatory pseudotumor (n-SCIPT): clinicopathologic characterization of a novel lesion of the lumbosacral spinal cord and nerve roots following intrathecal allogeneic stem cell intervention.
  Acta neuropathologica 2019 Sloan EA, Sampognaro PJ, Junn JC, Chin C, Jacques L, Ramachandran PS, DeRisi JL, Wilson MR, Kriegstein AR, Bollen AW, Solomon DA, Margeta M, Engstrom JW
• Recurrent non-canonical histone H3 mutations in spinal cord diffuse gliomas.
  Acta neuropathologica 2019 Sloan EA, Cooney T, Oberheim Bush NA, Buerki R, Taylor J, Clarke JL, Torkildson J, Kline C, Reddy A, Mueller S, Banerjee A, Butowski N, Chang S, Mummaneni PV, Chou D, Tan L, Theodosopoulos P, …
• A case of recurrent epilepsy-associated rosette-forming glioneuronal tumor with anaplastic transformation in the absence of therapy.
  Neuropathology : official journal of the Japanese Society of Neuropathology 2019 Halfpenny A, Ferris SP, Grafe M, Woltjer R, Selden N, Nazemi K, Perry A, Solomon DA, Gultekin SH, Moore S, Olson S, Lawce H, Lucas L, Corless CL, Wood MD
• An unusual recurrent high-grade glioneuronal tumor with MAP2K1 mutation and CDKN2A/B homozygous deletion.
  Acta neuropathologica communications 2019 Cheaney B, Bowden S, Krause K, Sloan EA, Perry A, Solomon DA, Han SJ, Wood MD
• Loss of ZNF750 in ocular and cutaneous sebaceous carcinoma.
  Journal of cutaneous pathology 2019 North JP, Solomon DA, Golovato J, Bloomer M, Benz SC, Cho RJ
• High-grade neuroepithelial tumor with BCOR exon 15 internal tandem duplication-a comprehensive clinical, radiographic, pathologic, and genomic analysis.
  Brain pathology (Zurich, Switzerland) 2019 Ferris SP, Velazquez Vega J, Aboian M, Lee JC, Van Ziffle J, Onodera C, Grenert JP, Saunders T, Chen YY, Banerjee A, Kline CN, Gupta N, Raffel C, Samuel D, Ruiz-Diaz I, Magaki S, Wilson D, Neltner J, …
• ALK-positive histiocytosis with KIF5B-ALK fusion in the central nervous system.
  Acta neuropathologica 2019 Lucas CG, Gilani A, Solomon DA, Liang X, Maher OM, Chamyan G, Kleinschmidt-Demasters BK, Perry A
• A pilot precision medicine trial for children with diffuse intrinsic pontine glioma-PNOC003: A report from the Pacific Pediatric Neuro-Oncology Consortium.
  International journal of cancer 2019 Mueller S, Jain P, Liang WS, Kilburn L, Kline C, Gupta N, Panditharatna E, Magge SN, Zhang B, Zhu Y, Crawford JR, Banerjee A, Nazemi K, Packer RJ, Petritsch CK, Truffaux N, Roos A, Nasser S, Phillips …
• Recurrent EP300-BCOR Fusions in Pediatric Gliomas With Distinct Clinicopathologic Features.
  Journal of neuropathology and experimental neurology 2019 Torre M, Meredith DM, Dubuc A, Solomon DA, Perry A, Vasudevaraja V, Serrano J, Snuderl M, Ligon KL, Alexandrescu S
• Recurrent KBTBD4 small in-frame insertions and absence of DROSHA deletion or DICER1 mutation differentiate pineal parenchymal tumor of intermediate differentiation (PPTID) from pineoblastoma.
  Acta neuropathologica 2019 Lee JC, Mazor T, Lao R, Wan E, Diallo AB, Hill NS, Thangaraj N, Wendelsdorf K, Samuel D, Kline CN, Banerjee A, Auguste K, Raffel C, Gupta N, Berger M, Raleigh DR, Shai A, Phillips JJ, Bollen AW, Tihan…
• Fertility treatment is associated with multiple meningiomas and younger age at diagnosis.
  Journal of neuro-oncology 2019 Shahin MN, Magill ST, Dalle Ore CL, Viner JA, Peters PN, Solomon DA, McDermott MW
• Preoperative MR Imaging to Differentiate Chordoid Meningiomas from Other Meningioma Histologic Subtypes.
  AJNR. American journal of neuroradiology 2019 Baal JD, Chen WC, Solomon DA, Pai JS, Lucas CH, Hara JH, Oberheim Bush NA, McDermott MW, Raleigh DR, Villanueva-Meyer JE
• Primary intracranial sarcomas with DICER1 mutation often contain prominent eosinophilic cytoplasmic globules and can occur in the setting of neurofibromatosis type 1.
  Acta neuropathologica 2019 Lee JC, Villanueva-Meyer JE, Ferris SP, Sloan EA, Hofmann JW, Hattab EM, Williams BJ, Guo H, Torkildson J, Florez A, Van Ziffle J, Onodera C, Grenert JP, Cho SJ, Horvai AE, Jones DTW, Pfister SM, …
• Clinicopathologic features of anaplastic myxopapillary ependymomas.
  Brain pathology (Zurich, Switzerland) 2019 Lee JC, Sharifai N, Dahiya S, Kleinschmidt-DeMasters BK, Rosenblum MK, Reis GF, Samuel D, Siongco AM, Santi M, Storm PB, Ferris SP, Bollen AW, Pekmezci M, Solomon DA, Tihan T, Perry A
• CRTC1-MAML2 fusion in mucoepidermoid carcinoma of the breast.
  Histopathology 2018 Bean GR, Krings G, Otis CN, Solomon DA, García JJ, van Zante A, Camelo-Piragua S, van Ziffle J, Chen YY
• The genetic landscape of anaplastic pleomorphic xanthoastrocytoma.
  Brain pathology (Zurich, Switzerland) 2018 Phillips JJ, Gong H, Chen K, Joseph NM, van Ziffle J, Bastian BC, Grenert JP, Kline CN, Mueller S, Banerjee A, Nicolaides T, Gupta N, Berger MS, Lee HS, Pekmezci M, Tihan T, Bollen AW, Perry A, Shieh …
• Oligodendrogliomas, IDH-mutant and 1p/19q-codeleted, arising during teenage years often lack TERT promoter mutation that is typical of their adult counterparts.
  Acta neuropathologica communications 2018 Lee J, Putnam AR, Chesier SH, Banerjee A, Raffel C, Van Ziffle J, Onodera C, Grenert JP, Bastian BC, Perry A, Solomon DA
• The genetic landscape of gliomas arising after therapeutic radiation.
  Acta neuropathologica 2018 López GY, Van Ziffle J, Onodera C, Grenert JP, Yeh I, Bastian BC, Clarke J, Oberheim Bush NA, Taylor J, Chang S, Butowski N, Banerjee A, Mueller S, Kline C, Torkildson J, Samuel D, Siongco A, Raffel C…
• Well-differentiated papillary mesothelioma of the peritoneum is genetically defined by mutually exclusive mutations in TRAF7 and CDC42.
  Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2018 Stevers M, Rabban JT, Garg K, Van Ziffle J, Onodera C, Grenert JP, Yeh I, Bastian BC, Zaloudek C, Solomon DA
• Myxoid glioneuronal tumor of the septum pellucidum and lateral ventricle is defined by a recurrent PDGFRA p.K385 mutation and DNT-like methylation profile.
  Acta neuropathologica 2018 Solomon DA, Korshunov A, Sill M, Jones DTW, Kool M, Pfister SM, Fan X, Bannykh S, Hu J, Danielpour M, Li R, Johnston J, Cham E, Cooney T, Sun PP, Oberheim Bush NA, McDermott M, Van Ziffle J, Onodera C…
• STAG2 Is a Biomarker for Prediction of Recurrence and Progression in Papillary Non-Muscle-Invasive Bladder Cancer.
  Clinical cancer research : an official journal of the American Association for Cancer Research 2018 Lelo A, Prip F, Harris BT, Solomon D, Berry DL, Chaldekas K, Kumar A, Simko J, Jensen JB, Bhattacharyya P, Mannion C, Kim JS, Philips G, Dyrskjøt L, Waldman T
• The genetic landscape of ganglioglioma.
  Acta neuropathologica communications 2018 Pekmezci M, Villanueva-Meyer JE, Goode B, Van Ziffle J, Onodera C, Grenert JP, Bastian BC, Chamyan G, Maher OM, Khatib Z, Kleinschmidt-DeMasters BK, Samuel D, Mueller S, Banerjee A, Clarke JL, Cooney …
• Cell of origin and mutation pattern define three clinically distinct classes of sebaceous carcinoma.
  Nature communications 2018 North JP, Golovato J, Vaske CJ, Sanborn JZ, Nguyen A, Wu W, Goode B, Stevers M, McMullen K, Perez White BE, Collisson EA, Bloomer M, Solomon DA, Benz SC, Cho RJ
• Spectrum and prevalence of genetic predisposition in medulloblastoma: a retrospective genetic study and prospective validation in a clinical trial cohort.
  The Lancet. Oncology 2018 Waszak SM, Northcott PA, Buchhalter I, Robinson GW, Sutter C, Groebner S, Grund KB, Brugières L, Jones DTW, Pajtler KW, Morrissy AS, Kool M, Sturm D, Chavez L, Ernst A, Brabetz S, Hain M, Zichner T, …
• STAG2 deficiency induces interferon responses via cGAS-STING pathway and restricts virus infection.
  Nature communications 2018 Ding S, Diep J, Feng N, Ren L, Li B, Ooi YS, Wang X, Brulois KF, Yasukawa LL, Li X, Kuo CJ, Solomon DA, Carette JE, Greenberg HB
• Genomic analysis of the origins and evolution of multicentric diffuse lower-grade gliomas.
  Neuro-oncology 2018 Hayes J, Yu Y, Jalbert LE, Mazor T, Jones LE, Wood MD, Walsh KM, Bengtsson H, Hong C, Oberndorfer S, Roetzer T, Smirnov IV, Clarke JL, Aghi MK, Chang SM, Nelson SJ, Woehrer A, Phillips JJ, Solomon DA,…
• A recurrent kinase domain mutation in PRKCA defines chordoid glioma of the third ventricle.
  Nature communications 2018 Goode B, Mondal G, Hyun M, Ruiz DG, Lin YH, Van Ziffle J, Joseph NM, Onodera C, Talevich E, Grenert JP, Hewedi IH, Snuderl M, Brat DJ, Kleinschmidt-DeMasters BK, Rodriguez FJ, Louis DN, Yong WH, Lopes…
• Early detection of recurrent medulloblastoma: the critical role of diffusion-weighted imaging.
  Neuro-oncology practice 2018 Aboian MS, Kline CN, Li Y, Solomon DA, Felton E, Banerjee A, Braunstein SE, Mueller S, Dillon WP, Cha S
• Deep sequencing of WNT-activated medulloblastomas reveals secondary SHH pathway activation.
  Acta neuropathologica 2018 Iorgulescu JB, Van Ziffle J, Stevers M, Grenert JP, Bastian BC, Chavez L, Stichel D, Buchhalter I, Samuel D, Nicolaides T, Banerjee A, Mueller S, Gupta N, Tihan T, Bollen AW, Northcott PA, Kool M, …
• Multinodular and vacuolating neuronal tumor of the cerebrum is a clonal neoplasm defined by genetic alterations that activate the MAP kinase signaling pathway.
  Acta neuropathologica 2018 Pekmezci M, Stevers M, Phillips JJ, Van Ziffle J, Bastian BC, Tsankova NM, Kleinschmidt-DeMasters BK, Rosenblum MK, Tihan T, Perry A, Solomon DA
• Personalized therapy: CNS HGNET-BCOR responsiveness to arsenic trioxide combined with radiotherapy.
  Oncotarget 2017 Paret C, Russo A, Otto H, Mayer A, Zahnreich S, Wagner W, Samuel D, Scharnhorst D, Solomon DA, Dhall G, Wong K, Bender H, Alt F, Wingerter A, Neu MA, Beck O, Prawitt D, Eder S, Henninger N, El Malki K…
• Adenomatoid tumors of the male and female genital tract are defined by TRAF7 mutations that drive aberrant NF-kB pathway activation.
  Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2017 Goode B, Joseph NM, Stevers M, Van Ziffle J, Onodera C, Talevich E, Grenert JP, Yeh I, Bastian BC, Phillips JJ, Garg K, Rabban JT, Zaloudek C, Solomon DA
• Multimodal molecular analysis of astroblastoma enables reclassification of most cases into more specific molecular entities.
  Brain pathology (Zurich, Switzerland) 2017 Wood MD, Tihan T, Perry A, Chacko G, Turner C, Pu C, Payne C, Yu A, Bannykh SI, Solomon DA
• Diffuse midline gliomas with subclonal H3F3A K27M mutation and mosaic H3.3 K27M mutant protein expression.
  Acta neuropathologica 2017 Lopez GY, Oberheim Bush NA, Phillips JJ, Bouffard JP, Moshel YA, Jaeckle K, Kleinschmidt-DeMasters BK, Rosenblum MK, Perry A, Solomon DA
• Familial melanoma-astrocytoma syndrome: synchronous diffuse astrocytoma and pleomorphic xanthoastrocytoma in a patient with germline CDKN2A/B deletion and a significant family history.
  Clinical neuropathology 2017 Chan AK, Han SJ, Choy W, Beleford D, Aghi MK, Berger MS, Shieh JT, Bollen AW, Perry A, Phillips JJ, Butowski N, Solomon DA
• Molecular testing for the clinical diagnosis of fibrolamellar carcinoma.
  Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2017 Graham RP, Yeh MM, Lam-Himlin D, Roberts LR, Terracciano L, Cruise MW, Greipp PT, Zreik RT, Jain D, Zaid N, Salaria SN, Jin L, Wang X, Rustin JG, Kerr SE, Sukov WR, Solomon DA, Kakar S, Waterhouse E, …
• Case-based review: pediatric medulloblastoma.
  Neuro-oncology practice 2017 Kline CN, Packer RJ, Hwang EI, Raleigh DR, Braunstein S, Raffel C, Bandopadhayay P, Solomon DA, Aboian M, Cha S, Mueller S
• Angiocentric glioma with MYB-QKI fusion located in the brainstem, rather than cerebral cortex.
  Acta neuropathologica 2017 Chan E, Bollen AW, Sirohi D, Van Ziffle J, Grenert JP, Kline CN, Tihan T, Perry A, Gupta N, Solomon DA
• Complete durable response of a pediatric anaplastic oligodendroglioma to temozolomide alone: Case report and review of literature.
  Pediatric blood & cancer 2017 Sorge C, Li R, Singh S, Reddy AT, Solomon DA, Perry A, Friedman GK
• Characterization of gliomas: from morphology to molecules.
  Virchows Archiv : an international journal of pathology 2017 Ferris SP, Hofmann JW, Solomon DA, Perry A
• Intraneural glomus tumor of "uncertain malignant potential" and with BRAF mutation in the median nerve - an unusual case.
  Clinical neuropathology 2017 Dahlin LB, Scherman P, Besjakov J, Lindberg E, Solomon DA, Horvai AE, Perry A
• Genomic profiling of breast secretory carcinomas reveals distinct genetics from other breast cancers and similarity to mammary analog secretory carcinomas.
  Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2017 Krings G, Joseph NM, Bean GR, Solomon D, Onodera C, Talevich E, Yeh I, Grenert JP, Hosfield E, Crawford ED, Jordan RC, van Zante A, Zaloudek C, Shin SJ, Chen YY
• Diffuse non-midline glioma with H3F3A K27M mutation: a prognostic and treatment dilemma.
  Acta neuropathologica communications 2017 López G, Oberheim Bush NA, Berger MS, Perry A, Solomon DA
• Targeted next-generation sequencing of pediatric neuro-oncology patients improves diagnosis, identifies pathogenic germline mutations, and directs targeted therapy.
  Neuro-oncology 2017 Kline CN, Joseph NM, Grenert JP, van Ziffle J, Talevich E, Onodera C, Aboian M, Cha S, Raleigh DR, Braunstein S, Torkildson J, Samuel D, Bloomer M, Campomanes AGA, Banerjee A, Butowski N, Raffel C, …
• Chordoid glioma of the third ventricle: report of a rapidly progressive case.
  Journal of neuro-oncology 2017 Erwood AA, Velazquez-Vega JE, Neill S, Solomon DA, Butowski N, Nowlan A, Dunbar E, Brat DJ
• Genetic confirmation that ependymoma can arise as part of multiple endocrine neoplasia type 1 (MEN1) syndrome.
  Acta neuropathologica 2017 Cuevas-Ocampo AK, Bollen AW, Goode B, Pajtler KW, Chavez L, Sharma T, Dai SC, McDermott M, Perry A, Korshunov A, Solomon DA
• Imaging Characteristics of Pediatric Diffuse Midline Gliomas with Histone H3 K27M Mutation.
  AJNR. American journal of neuroradiology 2017 Aboian MS, Solomon DA, Felton E, Mabray MC, Villanueva-Meyer JE, Mueller S, Cha S
• The role of histone modifications and telomere alterations in the pathogenesis of diffuse gliomas in adults and children.
  Journal of neuro-oncology 2017 Lee J, Solomon DA, Tihan T
• Uveal Ganglioneuroma due to Germline PTEN Mutation (Cowden Syndrome) Presenting as Unilateral Infantile Glaucoma.
  Ocular oncology and pathology 2016 DeParis SW, Bloomer M, Han Y, Vagefi MR, Shieh JTC, Solomon DA, Grenert J, de Alba Campomanes AG
• Genomic profiling of malignant peritoneal mesothelioma reveals recurrent alterations in epigenetic regulatory genes BAP1, SETD2, and DDX3X.
  Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2016 Joseph NM, Chen YY, Nasr A, Yeh I, Talevich E, Onodera C, Bastian BC, Rabban JT, Garg K, Zaloudek C, Solomon DA
• Activating NRF1-BRAF and ATG7-RAF1 fusions in anaplastic pleomorphic xanthoastrocytoma without BRAF p.V600E mutation.
  Acta neuropathologica 2016 Phillips JJ, Gong H, Chen K, Joseph NM, van Ziffle J, Jin LW, Bastian BC, Bollen AW, Perry A, Nicolaides T, Solomon DA, Shieh JT
• Pancreatic involvement by mesenchymal chondrosarcoma harboring the HEY1-NCOA2 gene fusion.
  Human pathology 2016 Cohen JN, Solomon DA, Horvai AE, Kakar S
• Correlation of exon 3 β-catenin mutations with glutamine synthetase staining patterns in hepatocellular adenoma and hepatocellular carcinoma.
  Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2016 Hale G, Liu X, Hu J, Xu Z, Che L, Solomon D, Tsokos C, Shafizadeh N, Chen X, Gill R, Kakar S
• Histopathologic review of pineal parenchymal tumors identifies novel morphologic subtypes and prognostic factors for outcome.
  Neuro-oncology 2016 Raleigh DR, Solomon DA, Lloyd SA, Lazar A, Garcia MA, Sneed PK, Clarke JL, McDermott MW, Berger MS, Tihan T, Haas-Kogan DA
• IDH1 mutation can be present in diffuse astrocytomas and giant cell glioblastomas of young children under 10 years of age.
  Acta neuropathologica 2016 Ferris SP, Goode B, Joseph NM, Kline CN, Samuel D, Gupta N, Bollen A, Perry A, Mueller S, Solomon DA
• Exploiting molecular biology for diagnosis and targeted management of pediatric low-grade gliomas.
  Future oncology (London, England) 2016 Garcia MA, Solomon DA, Haas-Kogan DA
• Inactivating MUTYH germline mutations in pediatric patients with high-grade midline gliomas.
  Neuro-oncology 2016 Kline CN, Joseph NM, Grenert JP, van Ziffle J, Yeh I, Bastian BC, Mueller S, Solomon DA
• Diffuse Midline Gliomas with Histone H3-K27M Mutation: A Series of 47 Cases Assessing the Spectrum of Morphologic Variation and Associated Genetic Alterations.
  Brain pathology (Zurich, Switzerland) 2015 Solomon DA, Wood MD, Tihan T, Bollen AW, Gupta N, Phillips JJ, Perry A
• Morphology and Immunohistochemistry for 2SC and FH Aid in Detection of Fumarate Hydratase Gene Aberrations in Uterine Leiomyomas From Young Patients.
  The American journal of surgical pathology 2015 Joseph NM, Solomon DA, Frizzell N, Rabban JT, Zaloudek C, Garg K
• Direct Cranial Nerve Involvement by Gliomas: Case Series and Review of the Literature.
  AJNR. American journal of neuroradiology 2015 Mabray MC, Glastonbury CM, Mamlouk MD, Punch GE, Solomon DA, Cha S
• Clinicopathologic features of a second patient with Ewing-like sarcoma harboring CIC-FOXO4 gene fusion.
  The American journal of surgical pathology 2014 Solomon DA, Brohl AS, Khan J, Miettinen M
• Pharmacologic inhibition of histone demethylation as a therapy for pediatric brainstem glioma.
  Nature medicine 2014 Hashizume R, Andor N, Ihara Y, Lerner R, Gan H, Chen X, Fang D, Huang X, Tom MW, Ngo V, Solomon D, Mueller S, Paris PL, Zhang Z, Petritsch C, Gupta N, Waldman TA, James CD
• Aneurysm of the posterior meningeal artery embedded within a dorsal exophytic medullary hemangioblastoma: surgical management and review of literature.
  Journal of cerebrovascular and endovascular neurosurgery 2014 Raygor KP, Rowland NC, Cooke DL, Solomon DA, Huang MC
• Mutational and functional analysis of the tumor-suppressor PTPRD in human melanoma.
  Human mutation 2014 Walia V, Prickett TD, Kim JS, Gartner JJ, Lin JC, Zhou M, Rosenberg SA, Elble RC, Solomon DA, Waldman T, Samuels Y
• Cohesin gene mutations in tumorigenesis: from discovery to clinical significance.
  BMB reports 2014 Solomon DA, Kim JS, Waldman T
• Glioblastoma cells containing mutations in the cohesin component STAG2 are sensitive to PARP inhibition.
  Molecular cancer therapeutics 2013 Bailey ML, O'Neil NJ, van Pel DM, Solomon DA, Waldman T, Hieter P
• Hemosiderotic fibrolipomatous tumor, not an entirely benign entity.
  The American journal of surgical pathology 2013 Solomon DA, Antonescu CR, Link TM, O'Donnell RJ, Folpe AL, Horvai AE
• Targeted therapy for BRAFV600E malignant astrocytoma.
  Clinical cancer research : an official journal of the American Association for Cancer Research 2011 Nicolaides TP, Li H, Solomon DA, Hariono S, Hashizume R, Barkovich K, Baker SJ, Paugh BS, Jones C, Forshew T, Hindley GF, Hodgson JG, Kim JS, Rowitch DH, Weiss WA, Waldman TA, James CD
• Mechanistic analysis of a DNA damage-induced, PTEN-dependent size checkpoint in human cells.
  Molecular and cellular biology 2011 Kim JS, Xu X, Li H, Solomon D, Lane WS, Jin T, Waldman T
• Integrated genomic analyses identify ERRFI1 and TACC3 as glioblastoma-targeted genes.
  Oncotarget 2010 Duncan CG, Killela PJ, Payne CA, Lampson B, Chen WC, Liu J, Solomon D, Waldman T, Towers AJ, Gregory SG, McDonald KL, McLendon RE, Bigner DD, Yan H
• IDH1(R132) mutation identified in one human melanoma metastasis, but not correlated with metastases to the brain.
  Biochemical and biophysical research communications 2010 Lopez GY, Reitman ZJ, Solomon D, Waldman T, Bigner DD, McLendon RE, Rosenberg SA, Samuels Y, Yan H
• Pharmacologic inhibition of cyclin-dependent kinases 4 and 6 arrests the growth of glioblastoma multiforme intracranial xenografts.
  Cancer research 2010 Michaud K, Solomon DA, Oermann E, Kim JS, Zhong WZ, Prados MD, Ozawa T, James CD, Waldman T
• Sample type bias in the analysis of cancer genomes.
  Cancer research 2009 Solomon DA, Kim JS, Ressom HW, Sibenaller Z, Ryken T, Jean W, Bigner D, Yan H, Waldman T
• Lack of inherited mutations of PTPRD in familial melanoma and melanoma-astrocytoma syndrome.
  Pigment cell & melanoma research 2009 Solomon DA, Kim JS, Yang XR, Tucker MA, Goldstein AM, Samuels Y, Waldman T
• Retinoblastoma/p107/p130 pocket proteins: protein dynamics and interactions with target gene promoters.
  The Journal of biological chemistry 2009 Stengel KR, Thangavel C, Solomon DA, Angus SP, Zheng Y, Knudsen ES
• Mutational inactivation of PTPRD in glioblastoma multiforme and malignant melanoma.
  Cancer research 2008 Solomon DA, Kim JS, Cronin JC, Sibenaller Z, Ryken T, Rosenberg SA, Ressom H, Jean W, Bigner D, Yan H, Samuels Y, Waldman T
• Conspirators in a capital crime: co-deletion of p18INK4c and p16INK4a/p14ARF/p15INK4b in glioblastoma multiforme.
  Cancer research 2008 Solomon DA, Kim JS, Jean W, Waldman T
• WAVE1 is required for oligodendrocyte morphogenesis and normal CNS myelination.
  The Journal of neuroscience : the official journal of the Society for Neuroscience 2006 Kim HJ, DiBernardo AB, Sloane JA, Rasband MN, Solomon D, Kosaras B, Kwak SP, Vartanian TK
• Dynamic targeting of the replication machinery to sites of DNA damage.
  The Journal of cell biology 2004 Solomon DA, Cardoso MC, Knudsen ES
• RB reversibly inhibits DNA replication via two temporally distinct mechanisms.
  Molecular and cellular biology 2004 Angus SP, Mayhew CN, Solomon DA, Braden WA, Markey MP, Okuno Y, Cardoso MC, Gilbert DM, Knudsen ES
• Hierarchical requirement of SWI/SNF in retinoblastoma tumor suppressor-mediated repression of Plk1.
  The Journal of biological chemistry 2004 Gunawardena RW, Siddiqui H, Solomon DA, Mayhew CN, Held J, Angus SP, Knudsen ES
• Analysis of RB action in DNA damage checkpoint response.
  Methods in molecular biology (Clifton, N.J.) 2004 Mayhew CN, Bosco EE, Solomon DA, Knudsen ES, Angus SP
• Histone deacetylation of RB-responsive promoters: requisite for specific gene repression but dispensable for cell cycle inhibition.
  Molecular and cellular biology 2003 Siddiqui H, Solomon DA, Gunawardena RW, Wang Y, Knudsen ES
• Retinoblastoma tumor suppressor: analyses of dynamic behavior in living cells reveal multiple modes of regulation.
  Molecular and cellular biology 2003 Angus SP, Solomon DA, Kuschel L, Hennigan RF, Knudsen ES
• Cyclin D1 splice variants. Differential effects on localization, RB phosphorylation, and cellular transformation.
  The Journal of biological chemistry 2003 Solomon DA, Wang Y, Fox SR, Lambeck TC, Giesting S, Lan Z, Senderowicz AM, Conti CJ, Knudsen ES
• Growth factor control of CNS myelination.
  Developmental neuroscience 2001 Park SK, Solomon D, Vartanian T