David Jablons, MD
Professor
Surgery
School of Medicine
David M. Jablons M.D., FACS is Professor and Chief of the Section of General Thoracic Surgery at UCSF, and Program Leader of Thoracic Oncology. Dr. Jablons is also Ada Distinguished Professor in Thoracic Oncology and Nan T. McEvoy Distinguished Professor of Thoracic Surgical Oncology.
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Dr. Jablons is Director of the Thoracic Oncology Lab, one of the largest in the Department of Surgery, with seven principal investigators, an enviable portfolio of NIH grants, and state-of-art-equipment. Utilizing next generation sequencing and leveraging one of the largest thoracic tissue banks in the world, the lab has compiled an enviable record of scientific discovery and invention including a life-saving prognostic assay that informs the decision for providing adjuvant therapy to early-stage lung cancer patients.
Dr. Jablons received his medical degree from Albany Medical College. During medical school, he was awarded an NCI preceptorship allowing him to train under Steven Rosenberg, a world-renowned surgeon and tumor immunologist. This experience kindled Dr. Jablons lifelong interest in translational and precision medicine. Dr. Jablons then completed his general surgery residency at Tufts-New England Medical Center and his thoracic surgery residency at what is now New York Presbyterian-Weill Cornell Medical Center. His mentors included Robert Ginsburg at Memorial Sloan-Kettering and David Sugarbaker at Brigham & Women's Hospital, both world-renown thoracic surgical oncologists. Dr. Jablons also served as a Navy commander while Chief of Thoracic Surgery at the Oakland Naval Hospital. In 1997, he was named Chief of General Thoracic Surgery at UCSF.
Dr. Jablons is a highly accomplished thoracic surgeon, widely sought out by patients in the Bay Area and world-wide. One patient, Bonnie J. Addario, after recovering from an arduous lung cancer surgery, started a foundation bearing her name she co-founded with Dr. Jablons. Today, the Addario Foundation is one of the leading underwriters of lung cancer research. Dr. Jablons has also been a dedicated teacher and outstanding mentor for both for clinical fellows and surgical residents, the latter including Dan Raz and Johannes Kratz, protégés with an enviable and prolific record of publications who helped spearhead development of predictive and prognostic tools for lung cancer treatment in the lab.
Dr. Jablons has been a trailblazer in educational outreach, co-founding the UCSF Thoracic Oncology Conference, an annual symposium that provided expert training for thousands of community surgeons for over a decade. He also was instrumental in establishing the China Clinical Trials Consortium to find more effective treatments for lung cancer, and to ameliorate the epidemic of lung cancer in China. In 2009, he led the effort to bring World Conference on Lung Cancer to San Francisco, the preeminent event in the field, in which he served as co-Chair.
He is a member of numerous professional organizations including the Society of Thoracic Surgeons, the American College of Chest Physicians, the American Association for Cancer Research and the International Association for the Study of Lung Cancer (IASLC). Highly respected by his peers, Dr. Jablons was named to the list of U.S. News "America's Top Doctors," a distinction reserved for the top 1% of physicians in the nation for a given specialty. Dr. Jablons was recently inducted into the American Surgical Society, the nation's most prestigious.
Awards
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- Surgical Resident Teaching Award, University of California, San Francisco, 2001
- Surgical Resident Teaching Award, University of California, San Francisco, 1999
Websites
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- UCSF Thoracic Oncology Laboratory (thoraciconcologylab.ucsf.edu)
- Clinical Profile at UCSF Medical Center (ucsfhealth.org)
- UCSF General Thoracic Surgery Website (thoracic.surgery.ucsf.edu)
- Academic Profile at UCSF Thoracic Oncology Program (top.ucsf.edu)
- Profile at UCSF Helen Diller Family Comprehensive Cancer Center (cancer.ucsf.edu)
Videos
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- New Lung Cancer Test Predicts Survival (youtube.com)
- The Times They are a Changing (youtube.com)
- A Passion for Research (youtube.com)
Grants and Projects
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Publications (266)
Top publication keywords:
Gene Expression Regulation, NeoplasticRepressor ProteinsErbB ReceptorsCarcinoma, Non-Small-Cell LungBiomarkers, TumorNeoplasm StagingAdaptor Proteins, Signal TransducingMesotheliomaAdenocarcinoma, Bronchiolo-AlveolarAdenocarcinomaLung NeoplasmsApoptosisPleural NeoplasmsGene SilencingWnt Proteins
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Rewiring of human lung cell lineage and mitotic networks in lung adenocarcinomas.
Nature communications 2013 Kim IJ, Quigley D, To MD, Pham P, Lin K, Jo B, Jen KY, Raz D, Kim J, Mao JH, Jablons D, Balmain A -
A prognostic assay to identify patients at high risk of mortality despite small, node-negative lung tumors.
JAMA 2012 Kratz JR, Van den Eeden SK, He J, Jablons DM, Mann MJ -
A practical molecular assay to predict survival in resected non-squamous, non-small-cell lung cancer: development and international validation studies.
Lancet (London, England) 2012 Kratz JR, He J, Van Den Eeden SK, Zhu ZH, Gao W, Pham PT, Mulvihill MS, Ziaei F, Zhang H, Su B, Zhi X, Quesenberry CP, Habel LA, Deng Q, Wang Z, Zhou J, Li H, Huang MC, Yeh CC, Segal MR, Ray MR, Jones… -
Evaluation of a chemical library of small-molecule Dishevelled antagonists that suppress tumor growth by down-regulating T-cell factor-mediated transcription.
Molecular cancer therapeutics 2008 You L, Xu Z, Punchihewa C, Jablons DM, Fujii N -
An antagonist of dishevelled protein-protein interaction suppresses beta-catenin-dependent tumor cell growth.
Cancer research 2007 Fujii N, You L, Xu Z, Uematsu K, Shan J, He B, Mikami I, Edmondson LR, Neale G, Zheng J, Guy RK, Jablons DM -
Targeting ADAM-mediated ligand cleavage to inhibit HER3 and EGFR pathways in non-small cell lung cancer.
Cancer cell 2006 Zhou BB, Peyton M, He B, Liu C, Girard L, Caudler E, Lo Y, Baribaud F, Mikami I, Reguart N, Yang G, Li Y, Yao W, Vaddi K, Gazdar AF, Friedman SM, Jablons DM, Newton RC, Fridman JS, Minna JD, Scherle … -
Randomized phase II trial comparing bevacizumab plus carboplatin and paclitaxel with carboplatin and paclitaxel alone in previously untreated locally advanced or metastatic non-small-cell lung cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2004 Johnson DH, Fehrenbacher L, Novotny WF, Herbst RS, Nemunaitis JJ, Jablons DM, Langer CJ, DeVore RF, Gaudreault J, Damico LA, Holmgren E, Kabbinavar F
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Novel dual action PARP and microtubule polymerization inhibitor AMXI-5001 powerfully inhibits growth of esophageal carcinoma both alone and in combination with radiotherapy.
American journal of cancer research 2024 Brand NR, Yang YW, Ding V, Dutta H, Peto CJ, Lemjabbar-Alaoui H, Jablons DM -
Randomized Phase II Trial Comparing Bevacizumab Plus Carboplatin and Paclitaxel With Carboplatin and Paclitaxel Alone in Previously Untreated Locally Advanced or Metastatic Non-Small-Cell Lung Cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2023 Johnson DH, Fehrenbacher L, Novotny WF, Herbst RS, Nemunaitis JJ, Jablons DM, Langer CJ, DeVore RF, Gaudreault J, Damico LA, Holmgren E, Kabbinavar F -
Comparative genomics between matched solid and lepidic portions of semi-solid lung adenocarcinomas.
Lung cancer (Amsterdam, Netherlands) 2023 Woodard GA, Ding V, Cho C, Brand NR, Kratz JR, Jones KD, Jablons DM -
SARS-CoV-2 infection of airway organoids reveals conserved use of Tetraspanin-8 by Ancestral, Delta, and Omicron variants.
Stem cell reports 2023 Hysenaj L, Little S, Kulhanek K, Magnen M, Bahl K, Gbenedio OM, Prinz M, Rodriguez L, Andersen C, Rao AA, Shen A, Lone JC, Lupin-Jimenez LC, Bonser LR, Serwas NK, Mick E, Khalid MM, Taha TY, Kumar R, … -
MK256 is a novel CDK8 inhibitor with potent antitumor activity in AML through downregulation of the STAT pathway.
Oncotarget 2022 Lee JC, Liu S, Wang Y, Liang Y, Jablons DM -
Genetic and immunologic features of recurrent stage I lung adenocarcinoma.
Scientific reports 2021 Kratz JR, Li JZ, Tsui J, Lee JC, Ding VW, Rao AA, Mann MJ, Chan V, Combes AJ, Krummel MF, Jablons DM -
Perioperative Lung Resection Outcomes After Implementation of a Multidisciplinary, Evidence-based Thoracic ERAS Program.
Annals of surgery 2021 Haro GJ, Sheu B, Marcus SG, Sarin A, Campbell L, Jablons DM, Kratz JR -
The effect of cullin 4A on lung cancer cell chemosensitivity to paclitaxel through p33ING1b regulation.
American journal of translational research 2021 Lung J, Chen YC, Lin YC, Li YC, You L, Jablons DM, Mao JH, Yang CT, Hung MS -
Improved outcomes and staging in non-small-cell lung cancer guided by a molecular assay.
Future oncology (London, England) 2021 Gupta AR, Woodard GA, Jablons DM, Mann MJ, Kratz JR -
Molecular Risk Stratification is Independent of EGFR Mutation Status in Identifying Early-Stage Non-Squamous Non-Small Cell Lung Cancer Patients at Risk for Recurrence and Likely to Benefit From Adjuvant Chemotherapy.
Clinical lung cancer 2021 Woodard GA, Kratz JR, Haro G, Gubens MA, Blakely CM, Jones KD, Mann MJ, Jablons DM -
SARS-CoV-2 infection studies in lung organoids identify TSPAN8 as novel mediator.
bioRxiv : the preprint server for biology 2021 Hysenaj L, Little S, Kulhanek K, Gbenedio OM, Rodriguez L, Shen A, Lone JC, Lupin-Jimenez LC, Bonser LR, Serwas NK, Bahl K, Mick E, Li JZ, Ding VW, Matsumoto S, Maishan M, Simoneau C, Fragiadakis G, … -
Extracellular sulfatases as potential blood-based biomarkers for early detection of lung cancer.
Experimental lung research 2021 Yang YW, Jablons DM, Lemjabbar-Alaoui H -
Resectability, Recurrence, and Risk Stratification of Giant Solitary Fibrous Tumors in the Thoracic Cavity.
Annals of surgical oncology 2021 Woodard GA, Fels Elliott DR, Yap A, Haro GJ, Kratz JR, Mann MJ, Jones KD, Jablons DM -
Bioinformatic Approaches to Validation and Functional Analysis of 3D Lung Cancer Models.
Cancers 2021 Li PJ, Roose JP, Jablons DM, Kratz JR -
A novel isoform of Homeodomain-interacting protein kinase-2 promotes YAP/TEAD transcriptional activity in NSCLC cells.
Oncotarget 2021 Dai Y, Kyoyama H, Yang YL, Wang Y, Liu S, Wang Y, Mao JH, Xu Z, Uematsu K, Jablons DM, You L -
Development of novel monoclonal antibodies and immunoassays for sensitive and specific detection of SULF1 endosulfatase.
Biochimica et biophysica acta. General subjects 2020 Yang YW, Phillips JJ, Jablons DM, Lemjabbar-Alaoui H -
Ponatinib is a potential therapeutic approach for malignant pleural mesothelioma.
Experimental lung research 2020 Yang YW, Marrufo A, Chase J, Woodard GA, Jablons DM, Lemjabbar-Alaoui H -
Evaluation of a National Comprehensive Cancer Network Guidelines-Based Decision Support Tool in Patients With Non-Small Cell Lung Cancer: A Nonrandomized Clinical Trial.
JAMA network open 2020 Wu SY, Lazar AA, Gubens MA, Blakely CM, Gottschalk AR, Jablons DM, Jahan TM, Wang VEH, Dunbar TL, Wong ML, Chan JW, Guthrie W, Belkora J, Yom SS -
Therapy-Induced Evolution of Human Lung Cancer Revealed by Single-Cell RNA Sequencing.
Cell 2020 Maynard A, McCoach CE, Rotow JK, Harris L, Haderk F, Kerr DL, Yu EA, Schenk EL, Tan W, Zee A, Tan M, Gui P, Lea T, Wu W, Urisman A, Jones K, Sit R, Kolli PK, Seeley E, Gesthalter Y, Le DD, Yamauchi KA… -
AMXI-5001, a novel dual parp1/2 and microtubule polymerization inhibitor for the treatment of human cancers.
American journal of cancer research 2020 Lemjabbar-Alaoui H, Peto CJ, Yang YW, Jablons DM -
The Crosstalk between Src and Hippo/YAP Signaling Pathways in Non-Small Cell Lung Cancer (NSCLC).
Cancers 2020 Hsu PC, Yang CT, Jablons DM, You L -
Surgery for pleural mesothelioma, when it is indicated and why: arguments against surgery for malignant pleural mesothelioma.
Translational lung cancer research 2020 Woodard GA, Jablons DM -
Inhibition of cyclin-dependent kinase 7 down-regulates yes-associated protein expression in mesothelioma cells.
Journal of cellular and molecular medicine 2019 Miao J, Kyoyama H, Liu L, Chan G, Wang Y, Urisman A, Yang YL, Liu S, Xu Z, Bin H, Li H, Jablons DM, You L -
Differential gene expression identifies KRT7 and MUC1 as potential metastasis-specific targets in sarcoma.
Cancer management and research 2019 Jiang L, Tolani B, Yeh CC, Fan Y, Reza JA, Horvai AE, Xia E, Kratz JR, Jablons DM, Mann MJ -
Case report: recurrent metastatic breast cancer in internal mammary dissection bed discovered at the time of coronary bypass.
Journal of cardiothoracic surgery 2019 Woodard GA, Lee H, Fels Elliott DR, Jones KD, Wong J, Jablons DM, Ihnken K -
Epidermal Growth Factor Receptor (EGFR) Pathway, Yes-Associated Protein (YAP) and the Regulation of Programmed Death-Ligand 1 (PD-L1) in Non-Small Cell Lung Cancer (NSCLC).
International journal of molecular sciences 2019 Hsu PC, Jablons DM, Yang CT, You L -
The crystal structure of the protein kinase HIPK2 reveals a unique architecture of its CMGC-insert region.
The Journal of biological chemistry 2019 Agnew C, Liu L, Liu S, Xu W, You L, Yeung W, Kannan N, Jablons D, Jura N -
Mesothelioma: Scientific clues for prevention, diagnosis, and therapy.
CA: a cancer journal for clinicians 2019 Carbone M, Adusumilli PS, Alexander HR, Baas P, Bardelli F, Bononi A, Bueno R, Felley-Bosco E, Galateau-Salle F, Jablons D, Mansfield AS, Minaai M, de Perrot M, Pesavento P, Rusch V, Severson DT, … -
Cucurbitacin E inhibits the Yes‑associated protein signaling pathway and suppresses brain metastasis of human non‑small cell lung cancer in a murine model.
Oncology reports 2019 Hsu PC, Tian B, Yang YL, Wang YC, Liu S, Urisman A, Yang CT, Xu Z, Jablons DM, You L -
Cul4A Modulates Invasion and Metastasis of Lung Cancer Through Regulation of ANXA10.
Cancers 2019 Hung MS, Chen YC, Lin P, Li YC, Hsu CC, Lung JH, You L, Xu Z, Mao JH, Jablons DM, Yang CT -
Incorporation of a Molecular Prognostic Classifier Improves Conventional Non-Small Cell Lung Cancer Staging.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 2019 Kratz JR, Haro GJ, Cook NR, He J, Van Den Eeden SK, Woodard GA, Gubens MA, Jahan TM, Jones KD, Kim IJ, He B, Jablons DM, Mann MJ -
Applications of Next-Generation Sequencing in Neoantigen Prediction and Cancer Vaccine Development.
Genetic testing and molecular biomarkers 2019 Lancaster EM, Jablons D, Kratz JR -
The Role of Yes-Associated Protein (YAP) in Regulating Programmed Death-Ligand 1 (PD-L1) in Thoracic Cancer.
Biomedicines 2018 Hsu PC, Yang CT, Jablons DM, You L -
Central Airway Obstruction Due to Tracheal Glomus Tumor.
The Thoracic and cardiovascular surgeon reports 2018 Haro GJ, Seeley EJ, Jablons DM, Kratz JR -
Pathologic Complete Response to Neoadjuvant Crizotinib in a Lung Adenocarcinoma Patient With a MET Exon 14 Skipping Mutation.
Clinical lung cancer 2018 Rotow JK, Woodard GA, Urisman A, McCoach CE, Bivona TG, Elicker BM, Jablons DM, Blakely CM -
Scientific Advances and New Frontiers in Mesothelioma Therapeutics.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 2018 Mutti L, Peikert T, Robinson BWS, Scherpereel A, Tsao AS, de Perrot M, Woodard GA, Jablons DM, Wiens J, Hirsch FR, Yang H, Carbone M, Thomas A, Hassan R -
Expansion of hedgehog disrupts mesenchymal identity and induces emphysema phenotype.
The Journal of clinical investigation 2018 Wang C, de Mochel NSR, Christenson SA, Cassandras M, Moon R, Brumwell AN, Byrnes LE, Li A, Yokosaki Y, Shan P, Sneddon JB, Jablons D, Lee PJ, Matthay MA, Chapman HA, Peng T -
Transfer of multiple loci of donor's genes to induce recipient tolerance in organ transplantation.
Experimental and therapeutic medicine 2018 Li T, Zhang W, Xu Q, Li S, Tong X, Ding J, Li H, Hou S, Xu Z, Jablons DM, You L -
Inhibition of yes-associated protein down-regulates PD-L1 (CD274) expression in human malignant pleural mesothelioma.
Journal of cellular and molecular medicine 2018 Hsu PC, Miao J, Wang YC, Zhang WQ, Yang YL, Wang CW, Yang CT, Huang Z, You J, Xu Z, Jablons DM, You L -
Inhibition of yes-associated protein suppresses brain metastasis of human lung adenocarcinoma in a murine model.
Journal of cellular and molecular medicine 2018 Hsu PC, Miao J, Huang Z, Yang YL, Xu Z, You J, Dai Y, Yeh CC, Chan G, Liu S, Urisman A, Yang CT, Jablons DM, You L -
Preclinical characterization of therapeutic antibodies targeted at the carboxy-terminus of Sonic hedgehog.
Oncotarget 2018 Tolani B, Hoang NT, Acevedo LA, Giroux Leprieur E, Li H, He B, Jablons DM -
Old Sonic Hedgehog, new tricks: a new paradigm in thoracic malignancies.
Oncotarget 2018 Giroux Leprieur E, Jablons DM, He B -
YAP regulates PD-L1 expression in human NSCLC cells.
Oncotarget 2017 Miao J, Hsu PC, Yang YL, Xu Z, Dai Y, Wang Y, Chan G, Huang Z, Hu B, Li H, Jablons DM, You L -
Gli is activated and promotes epithelial-mesenchymal transition in human esophageal adenocarcinoma.
Oncotarget 2017 Wang L, Jin JQ, Zhou Y, Tian Z, Jablons DM, He B -
Membrane-bound full-length Sonic Hedgehog identifies cancer stem cells in human non-small cell lung cancer.
Oncotarget 2017 Giroux Leprieur E, Tolani B, Li H, Leguay F, Hoang NT, Acevedo LA, Jin JQ, Tseng HH, Yue D, Kim IJ, Wislez M, Wang C, Jablons DM, He B -
Checkpoint inhibitor is active against large cell neuroendocrine carcinoma with high tumor mutation burden.
Journal for immunotherapy of cancer 2017 Wang VE, Urisman A, Albacker L, Ali S, Miller V, Aggarwal R, Jablons D -
Hippo pathway in lung development.
Journal of thoracic disease 2017 Dai Y, Jablons D, You L -
Systematic comparison of two whole-genome amplification methods for targeted next-generation sequencing using frozen and FFPE normal and cancer tissues.
Scientific reports 2017 Mendez P, Fang LT, Jablons DM, Kim IJ -
Drug development against the hippo pathway in mesothelioma.
Translational lung cancer research 2017 Woodard GA, Yang YL, You L, Jablons DM -
Adjuvant Chemotherapy Guided by Molecular Profiling and Improved Outcomes in Early Stage, Non-Small-Cell Lung Cancer.
Clinical lung cancer 2017 Woodard GA, Wang SX, Kratz JR, Zoon-Besselink CT, Chiang CY, Gubens MA, Jahan TM, Blakely CM, Jones KD, Mann MJ, Jablons DM -
DCLK1 is correlated with MET and ERK5 expression, and associated with prognosis in malignant pleural mesothelioma.
International journal of oncology 2017 Wang H, Dai YY, Zhang WQ, Hsu PC, Yang YL, Wang YC, Chan G, Au A, Xu ZD, Jiang SJ, Wang W, Jablons DM, You L -
Targeting YAP in malignant pleural mesothelioma.
Journal of cellular and molecular medicine 2017 Zhang WQ, Dai YY, Hsu PC, Wang H, Cheng L, Yang YL, Wang YC, Xu ZD, Liu S, Chan G, Hu B, Li H, Jablons DM, You L -
Management of Lung Cancer Invading the Superior Sulcus.
Thoracic surgery clinics 2017 Kratz JR, Woodard G, Jablons DM -
Mobile Genome Express (MGE): A comprehensive automatic genetic analyses pipeline with a mobile device.
PloS one 2017 Yoon JH, Kim TW, Mendez P, Jablons DM, Kim IJ -
YAP1 regulates ABCG2 and cancer cell side population in human lung cancer cells.
Oncotarget 2017 Dai Y, Liu S, Zhang WQ, Yang YL, Hang P, Wang H, Cheng L, Hsu PC, Wang YC, Xu Z, Jablons DM, You L -
Gli promotes epithelial-mesenchymal transition in human lung adenocarcinomas.
Oncotarget 2016 Li H, Yue D, Jin JQ, Woodard GA, Tolani B, Luh TM, Giroux-Leprieur E, Mo M, Chen Z, Che J, Zhang Z, Zhou Y, Wang L, Hao X, Jablons D, Wang C, He B -
FAIM2, as a novel diagnostic maker and a potential therapeutic target for small-cell lung cancer and atypical carcinoid.
Scientific reports 2016 Kang HC, Kim JI, Chang HK, Woodard G, Choi YS, Ku JL, Jablons DM, Kim IJ -
Hybrid minimally invasive Ivor Lewis esophagectomy after neoadjuvant chemoradiation yields excellent long-term survival outcomes with minimal morbidity.
Journal of surgical oncology 2016 Woodard GA, Crockard JC, Clary-Macy C, Zoon-Besselink CT, Jones K, Korn WM, Ko AH, Gottschalk AR, Rogers SJ, Jablons DM -
Development of a robust DNA quality and quantity assessment qPCR assay for targeted next-generation sequencing library preparation.
International journal of oncology 2016 Dang J, Mendez P, Lee S, Kim JW, Yoon JH, Kim TW, Sailey CJ, Jablons DM, Kim IJ -
YAP promotes erlotinib resistance in human non-small cell lung cancer cells.
Oncotarget 2016 Hsu PC, You B, Yang YL, Zhang WQ, Wang YC, Xu Z, Dai Y, Liu S, Yang CT, Li H, Hu B, Jablons DM, You L -
Spotlight on afatinib and its potential in the treatment of squamous cell lung cancer: the evidence so far.
Therapeutics and clinical risk management 2016 Xu Y, Ding VW, Zhang H, Zhang X, Jablons D, He B -
Comprehensive evaluation and validation of targeted next-generation sequencing performance in two clinical laboratories.
International journal of oncology 2016 Mendez P, Dang J, Kim JW, Lee S, Yoon JH, Kim T, Sailey CJ, Jablons DM, Kim IJ -
Knockdown of cullin 4A inhibits growth and increases chemosensitivity in lung cancer cells.
Journal of cellular and molecular medicine 2016 Hung MS, Chen IC, You L, Jablons DM, Li YC, Mao JH, Xu Z, Lung JH, Yang CT, Liu ST -
SULF2 Expression Is a Potential Diagnostic and Prognostic Marker in Lung Cancer.
PloS one 2016 Lui NS, Yang YW, van Zante A, Buchanan P, Jablons DM, Lemjabbar-Alaoui H -
Whole exome and targeted deep sequencing identify genome-wide allelic loss and frequent SETDB1 mutations in malignant pleural mesotheliomas.
Oncotarget 2016 Kang HC, Kim HK, Lee S, Mendez P, Kim JW, Woodard G, Yoon JH, Jen KY, Fang LT, Jones K, Jablons DM, Kim IJ -
Lung Cancer Staging and Prognosis.
Cancer treatment and research 2016 Woodard GA, Jones KD, Jablons DM -
Knockdown of Cul4A increases chemosensitivity to gemcitabine through upregulation of TGFBI in lung cancer cells.
Oncology reports 2015 Hung MS, Chen IC, You L, Jablons DM, Li YC, Mao JH, Xu Z, Hsieh MJ, Lin YC, Yang CT, Liu ST, Tsai YH -
Cul4A overexpression associated with Gli1 expression in malignant pleural mesothelioma.
Journal of cellular and molecular medicine 2015 Yang YL, Ni J, Hsu PC, Mao JH, Hsieh D, Xu A, Chan G, Au A, Xu Z, Jablons DM, You L -
EMX2 Is a Predictive Marker for Adjuvant Chemotherapy in Lung Squamous Cell Carcinomas.
PloS one 2015 Yue D, Li H, Che J, Zhang Y, Tolani B, Mo M, Zhang H, Zheng Q, Yang Y, Cheng R, Jin JQ, Luh TW, Yang C, Tseng HH, Giroux-Leprieur E, Woodard GA, Hao X, Wang C, Jablons DM, He B -
Operative and Perioperative Pulmonary Emboli.
Thoracic surgery clinics 2015 Cox JC, Jablons DM -
Analysis of lung tumor initiation and progression in transgenic mice for Cre-inducible overexpression of Cul4A gene.
Thoracic cancer 2015 Wang Y, Xu Z, Mao JH, Hung MS, Hsieh D, Au A, Jablons DM, You L -
PR-Set7 is Degraded in a Conditional Cul4A Transgenic Mouse Model of Lung Cancer.
Zhongguo fei ai za zhi = Chinese journal of lung cancer 2015 Wang Y, Xu Z, Mao JH, Hsieh D, Au A, Jablons DM, Li H, You L -
Transforming Growth Factor-β and Interleukin-1β Signaling Pathways Converge on the Chemokine CCL20 Promoter.
The Journal of biological chemistry 2015 Brand OJ, Somanath S, Moermans C, Yanagisawa H, Hashimoto M, Cambier S, Markovics J, Bondesson AJ, Hill A, Jablons D, Wolters P, Lou J, Marks JD, Baron JL, Nishimura SL -
NF-κB-activating complex engaged in response to EGFR oncogene inhibition drives tumor cell survival and residual disease in lung cancer.
Cell reports 2015 Blakely CM, Pazarentzos E, Olivas V, Asthana S, Yan JJ, Tan I, Hrustanovic G, Chan E, Lin L, Neel DS, Newton W, Bobb KL, Fouts TR, Meshulam J, Gubens MA, Jablons DM, Johnson JR, Bandyopadhyay S, … -
Genetic variation in the functional ENG allele inherited from the non-affected parent associates with presence of pulmonary arteriovenous malformation in hereditary hemorrhagic telangiectasia 1 (HHT1) and may influence expression of PTPN14.
Frontiers in genetics 2015 Letteboer TG, Benzinou M, Merrick CB, Quigley DA, Zhau K, Kim IJ, To MD, Jablons DM, van Amstel JK, Westermann CJ, Giraud S, Dupuis-Girod S, Lesca G, Berg JH, Balmain A, Akhurst RJ -
Inhibition of ERK1/2 down-regulates the Hippo/YAP signaling pathway in human NSCLC cells.
Oncotarget 2015 You B, Yang YL, Xu Z, Dai Y, Liu S, Mao JH, Tetsu O, Li H, Jablons DM, You L -
Wnt7A is a putative prognostic and chemosensitivity marker in human malignant pleural mesothelioma.
Oncology reports 2015 Hirata T, Zheng Q, Chen Z, Kinoshita H, Okamoto J, Kratz J, Li H, Lui N, Do H, Cheng T, Tseng HH, Koizumi K, Shimizu K, Zhou HM, Jablons D, He B -
The Latest in Surgical Management of Stage IIIA Non-Small Cell Lung Cancer: Video-Assisted Thoracic Surgery and Tumor Molecular Profiling.
American Society of Clinical Oncology educational book. American Society of Clinical Oncology. Annual Meeting 2015 Woodard GA, Jablons DM -
CK2α, over-expressed in human malignant pleural mesothelioma, regulates the Hedgehog signaling pathway in mesothelioma cells.
Journal of experimental & clinical cancer research : CR 2014 Zhang S, Yang YL, Wang Y, You B, Dai Y, Chan G, Hsieh D, Kim IJ, Fang LT, Au A, Stoppler HJ, Xu Z, Jablons DM, You L -
Measurement of genome-wide DNA methylation predicts survival benefits from chemotherapy in non-small cell lung cancer.
Journal of cancer research and clinical oncology 2014 Mo ML, Ma J, Chen Z, Wei B, Li H, Zhou Y, Shi H, Tolani B, Jin JQ, Tseng HH, Shen D, Zhan Y, Li J, Jablons DM, Zhang RQ, Guo Y, He B, Zhou HM -
Identification of recurrent FGFR3-TACC3 fusion oncogenes from lung adenocarcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2014 Capelletti M, Dodge ME, Ercan D, Hammerman PS, Park SI, Kim J, Sasaki H, Jablons DM, Lipson D, Young L, Stephens PJ, Miller VA, Lindeman NI, Munir KJ, Richards WG, Jänne PA -
Prognostic molecular assay might improve identification of patients at risk for recurrence in early-stage non-small-cell lung cancer.
Clinical lung cancer 2014 Woodard GA, Gubens MA, Jahan TM, Jones KD, Kukreja J, Theodore PR, Cardozo S, Jew G, Clary-Macy C, Jablons DM, Mann MJ -
An alternative way to initiate Notch1 signaling in non-small cell lung cancer.
Translational lung cancer research 2014 Yang YL, Jablons D, You L -
Divergent management strategies for typical versus atypical carcinoid tumors of the thoracic cavity.
American journal of clinical oncology 2014 Okoye CC, Jablons DM, Jahan TM, Kukreja J, Cardozo S, Yom SS -
The homeobox gene EMX2 is a prognostic and predictive marker in malignant pleural mesothelioma.
Lung cancer (Amsterdam, Netherlands) 2014 Giroux Leprieur E, Hirata T, Mo M, Chen Z, Okamoto J, Clement G, Li H, Wislez M, Jablons DM, He B -
Selective targeting of TGF-β activation to treat fibroinflammatory airway disease.
Science translational medicine 2014 Minagawa S, Lou J, Seed RI, Cormier A, Wu S, Cheng Y, Murray L, Tsui P, Connor J, Herbst R, Govaerts C, Barker T, Cambier S, Yanagisawa H, Goodsell A, Hashimoto M, Brand OJ, Cheng R, Ma R, McKnelly KJ… -
Lung tumourigenesis in a conditional Cul4A transgenic mouse model.
The Journal of pathology 2014 Yang YL, Hung MS, Wang Y, Ni J, Mao JH, Hsieh D, Au A, Kumar A, Quigley D, Fang LT, Yeh CC, Xu Z, Jablons DM, You L -
Hedgehog/Gli promotes epithelial-mesenchymal transition in lung squamous cell carcinomas.
Journal of experimental & clinical cancer research : CR 2014 Yue D, Li H, Che J, Zhang Y, Tseng HH, Jin JQ, Luh TM, Giroux-Leprieur E, Mo M, Zheng Q, Shi H, Zhang H, Hao X, Wang C, Jablons DM, He B -
A positive feedback between p53 and miR-34 miRNAs mediates tumor suppression.
Genes & development 2014 Okada N, Lin CP, Ribeiro MC, Biton A, Lai G, He X, Bu P, Vogel H, Jablons DM, Keller AC, Wilkinson JE, He B, Speed TP, He L -
Aggressive and minimally invasive surgery for pulmonary metastasis of sarcoma.
The Journal of thoracic and cardiovascular surgery 2014 Reza J, Sammann A, Jin C, Horvai A, Hudnall M, Jablons DM, Jahan T, Kornak J, Mann MJ -
Comprehensive genomic analyses of a metastatic colon cancer to the lung by whole exome sequencing and gene expression analysis.
International journal of oncology 2013 Fang LT, Lee S, Choi H, Kim HK, Jew G, Kang HC, Chen L, Jablons D, Kim IJ -
VATS lobectomy facilitates the delivery of adjuvant docetaxel-carboplatin chemotherapy in patients with non-small cell lung cancer.
Journal of thoracic disease 2013 Zhi X, Gao W, Han B, Yang Y, Li H, Liu D, Wang C, Min G, Long H, Rigas JR, Carey M, Jahan T, Sammann A, Reza J, Wang D, Mann MJ, Jablons DM, He J, China Clinical Trials Consortium -
Hematein, a casein kinase II inhibitor, inhibits lung cancer tumor growth in a murine xenograft model.
International journal of oncology 2013 Hung MS, Xu Z, Chen Y, Smith E, Mao JH, Hsieh D, Lin YC, Yang CT, Jablons DM, You L -
Desmoplastic fibroma of the spine causing severe mediastinal compression and brachial plexus encasement: report of 2 cases.
Journal of neurosurgery. Spine 2013 Lau D, Yarlagadda J, Jahan T, Jablons D, Chou D -
Down-regulation of SIX3 is associated with clinical outcome in lung adenocarcinoma.
PloS one 2013 Mo ML, Okamoto J, Chen Z, Hirata T, Mikami I, Bosco-Clément G, Li H, Zhou HM, Jablons DM, He B -
Tumor-infiltrating regulatory T cells inhibit endogenous cytotoxic T cell responses to lung adenocarcinoma.
Journal of immunology (Baltimore, Md. : 1950) 2013 Ganesan AP, Johansson M, Ruffell B, Yagui-Beltrán A, Beltran A, Lau J, Jablons DM, Coussens LM -
Coumestrol from the national cancer Institute's natural product library is a novel inhibitor of protein kinase CK2.
BMC pharmacology & toxicology 2013 Liu S, Hsieh D, Yang YL, Xu Z, Peto C, Jablons DM, You L -
Frizzled-8 receptor is activated by the Wnt-2 ligand in non-small cell lung cancer.
BMC cancer 2013 Bravo DT, Yang YL, Kuchenbecker K, Hung MS, Xu Z, Jablons DM, You L -
Analytical validation of a practical molecular assay prognostic of survival in nonsquamous non-small cell lung cancer.
Diagnostic molecular pathology : the American journal of surgical pathology, part B 2013 Kratz JR, Tham PT, Mulvihill MS, Ziaei F, Ray MR, Hurst JW, Segal MR, Berryman DM, Chu W, He B, Jablons DM, Mann MJ -
International trial of adjuvant therapy in high risk stage I non-squamous cell carcinoma identified by a 14-gene prognostic signature.
Translational lung cancer research 2013 Kratz JR, Mann MJ, Jablons DM -
Detection of E2A-PBX1 fusion transcripts in human non-small-cell lung cancer.
Journal of experimental & clinical cancer research : CR 2013 Mo ML, Chen Z, Zhou HM, Li H, Hirata T, Jablons DM, He B -
Targeting Gli transcription activation by small molecule suppresses tumor growth.
Oncogene 2013 Bosco-Clément G, Zhang F, Chen Z, Zhou HM, Li H, Mikami I, Hirata T, Yagui-Beltran A, Lui N, Do HT, Cheng T, Tseng HH, Choi H, Fang LT, Kim IJ, Yue D, Wang C, Zheng Q, Fujii N, Mann M, Jablons DM, He … -
Inhibition of CK2α down-regulates Notch1 signalling in lung cancer cells.
Journal of cellular and molecular medicine 2013 Zhang S, Long H, Yang YL, Wang Y, Hsieh D, Li W, Au A, Stoppler HJ, Xu Z, Jablons DM, You L -
Gli as a novel therapeutic target in malignant pleural mesothelioma.
PloS one 2013 Li H, Lui N, Cheng T, Tseng HH, Yue D, Giroux-Leprieur E, Do HT, Sheng Q, Jin JQ, Luh TW, Jablons DM, He B -
Prognostic assay in small, node-negative non-small cell lung cancer--reply.
JAMA 2013 Mann MJ, Jablons DM, Kratz JR -
SMO expression level correlates with overall survival in patients with malignant pleural mesothelioma.
Journal of experimental & clinical cancer research : CR 2013 Zhang Y, He J, Zhang F, Li H, Yue D, Wang C, Jablons DM, He B, Lui N -
Molecular prognostication of non-small cell lung cancer.
Seminars in thoracic and cardiovascular surgery 2013 Tsao MS, Jablons DM -
Identification of pY654-β-catenin as a critical co-factor in hypoxia-inducible factor-1α signaling and tumor responses to hypoxia.
Oncogene 2012 Xi Y, Wei Y, Sennino B, Ulsamer A, Kwan I, Brumwell AN, Tan K, Aghi MK, McDonald DM, Jablons DM, Chapman HA -
SULF2 expression by immunohistochemistry and overall survival in oesophageal cancer: a cohort study.
BMJ open 2012 Lui NS, van Zante A, Rosen SD, Jablons DM, Lemjabbar-Alaoui H -
The role of stem cells in airway repair: implications for the origins of lung cancer.
Chinese journal of cancer 2012 Mulvihill MS, Kratz JR, Pham P, Jablons DM, He B -
Gremlin is overexpressed in lung adenocarcinoma and increases cell growth and proliferation in normal lung cells.
PloS one 2012 Mulvihill MS, Kwon YW, Lee S, Fang LT, Choi H, Ray R, Kang HC, Mao JH, Jablons D, Kim IJ -
A somatic TSHR mutation in a patient with lung adenocarcinoma with bronchioloalveolar carcinoma, coronary artery disease and severe chronic obstructive pulmonary disease.
Oncology reports 2012 Kim JW, Lee S, Lui N, Choi H, Mulvihill M, Fang LT, Kang HC, Kwon YW, Jablons D, Kim IJ -
Inhibition of CK2α down-regulates Hedgehog/Gli signaling leading to a reduction of a stem-like side population in human lung cancer cells.
PloS one 2012 Zhang S, Wang Y, Mao JH, Hsieh D, Kim IJ, Hu LM, Xu Z, Long H, Jablons DM, You L -
The expression of Dishevelled-3 and glutamine metabolism in malignant pleural mesothelioma.
Journal of clinical pathology 2012 Li T, Hou SC, Mao JH, Wang YC, Lu XD, Tan JL, You B, Liu YP, Ni J, Au A, Jablons DM, Xu Z, You L -
One size does not fit all lung cancer patients.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 2012 Yom SS, Chen CP, Jahan TM, Jablons DM -
Development of a rapid and practical mutation screening assay for human lung adenocarcinoma.
International journal of oncology 2012 Choi H, Kratz J, Pham P, Lee S, Ray R, Kwon YW, Mao JH, Kang HC, Jablons D, Kim IJ -
Implications of delayed initiation of radiotherapy: accelerated repopulation after induction chemotherapy for stage III non-small cell lung cancer.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 2011 Chen CP, Weinberg VK, Jahan TM, Jablons DM, Yom SS -
Interleukin-1beta induces increased transcriptional activation of the transforming growth factor-beta-activating integrin subunit beta8 through altering chromatin architecture.
The Journal of biological chemistry 2011 Markovics JA, Araya J, Cambier S, Somanath S, Gline S, Jablons D, Hill A, Wolters PJ, Nishimura SL -
Wnt and hedgehog gene pathway expression in serous ovarian cancer.
International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 2011 Schmid S, Bieber M, Zhang F, Zhang M, He B, Jablons D, Teng NN -
The Bcl-2 repertoire of mesothelioma spheroids underlies acquired apoptotic multicellular resistance.
Cell death & disease 2011 Barbone D, Ryan JA, Kolhatkar N, Chacko AD, Jablons DM, Sugarbaker DJ, Bueno R, Letai AG, Coussens LM, Fennell DA, Broaddus VC -
Mouse and human lung fibroblasts regulate dendritic cell trafficking, airway inflammation, and fibrosis through integrin αvβ8-mediated activation of TGF-β.
The Journal of clinical investigation 2011 Kitamura H, Cambier S, Somanath S, Barker T, Minagawa S, Markovics J, Goodsell A, Publicover J, Reichardt L, Jablons D, Wolters P, Hill A, Marks JD, Lou J, Pittet JF, Gauldie J, Baron JL, Nishimura SL -
Downregulation of EMX2 is associated with clinical outcomes in lung adenocarcinoma patients.
Clinical lung cancer 2011 Okamoto J, Kratz JR, Hirata T, Mikami I, Raz D, Segal M, Chen Z, Zhou HM, Pham P, Li H, Yagui-Beltran A, Beltran A, Ray MR, Koizumi K, Shimizu K, Jablons D, He B -
Transgenic mice for cre-inducible overexpression of the Cul4A gene.
Genesis (New York, N.Y. : 2000) 2011 Li T, Hung MS, Wang Y, Mao JH, Tan JL, Jahan K, Roos H, Xu Z, Jablons DM, You L -
Cul4A is an oncogene in malignant pleural mesothelioma.
Journal of cellular and molecular medicine 2011 Hung MS, Mao JH, Xu Z, Yang CT, Yu JS, Harvard C, Lin YC, Bravo DT, Jablons DM, You L -
The expression of CXCR4, CXCL12 and CXCR7 in malignant pleural mesothelioma.
The Journal of pathology 2011 Li T, Li H, Wang Y, Harvard C, Tan JL, Au A, Xu Z, Jablons DM, You L -
Adenovirus-mediated SOCS3 gene transfer inhibits the growth and enhances the radiosensitivity of human non-small cell lung cancer cells.
Oncology reports 2010 Lin YC, Lin CK, Tsai YH, Weng HH, Li YC, You L, Chen JK, Jablons DM, Yang CT -
Inhibition of activated phosphatidylinositol 3-kinase/AKT pathway in malignant pleural mesothelioma leads to G1 cell cycle arrest.
Oncology reports 2010 Mikami I, Zhang F, Hirata T, Okamoto J, Koizumi K, Shimizu K, Jablons D, He B -
Lung cancer therapeutics that target signaling pathways: an update.
Expert review of respiratory medicine 2010 Ray MR, Jablons D, He B -
EMX2 is epigenetically silenced and suppresses growth in human lung cancer.
Oncogene 2010 Okamoto J, Hirata T, Chen Z, Zhou HM, Mikami I, Li H, Yagui-Beltran A, Beltran A, Johansson M, Coussens LM, Clement G, Shi Y, Zhang F, Koizumi K, Shimizu K, Jablons D, He B -
Functional polymorphism of the CK2alpha intronless gene plays oncogenic roles in lung cancer.
PloS one 2010 Hung MS, Lin YC, Mao JH, Kim IJ, Xu Z, Yang CT, Jablons DM, You L -
Transcription of the transforming growth factor beta activating integrin beta8 subunit is regulated by SP3, AP-1, and the p38 pathway.
The Journal of biological chemistry 2010 Markovics JA, Araya J, Cambier S, Jablons D, Hill A, Wolters PJ, Nishimura SL -
Cancer stem cells in lung tumorigenesis.
The Annals of thoracic surgery 2010 Kratz JR, Yagui-Beltrán A, Jablons DM -
Lack of NKX2.2 expression in bronchopulmonary typical carcinoid tumors: implications for patients with neuroendocrine tumor metastases and unknown primary site.
The Journal of surgical research 2010 Wang YC, Iezza G, Zuraek MB, Jablons DM, Theodore PR, Bergsland EK, Donner DB, Warren RS, Nakakura EK -
Organic cation transporters modulate the uptake and cytotoxicity of picoplatin, a third-generation platinum analogue.
Molecular cancer therapeutics 2010 More SS, Li S, Yee SW, Chen L, Xu Z, Jablons DM, Giacomini KM -
A safe and reproducible anastomotic technique for minimally invasive Ivor Lewis oesophagectomy: the circular-stapled anastomosis with the trans-oral anvil.
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 2010 Campos GM, Jablons D, Brown LM, Ramirez RM, Rabl C, Theodore P -
Procaine and procainamide inhibit the Wnt canonical pathway by promoter demethylation of WIF-1 in lung cancer cells.
Oncology reports 2009 Gao Z, Xu Z, Hung MS, Lin YC, Wang T, Gong M, Zhi X, Jablons DM, You L -
Discovery of molecular subtypes in leiomyosarcoma through integrative molecular profiling.
Oncogene 2009 Beck AH, Lee CH, Witten DM, Gleason BC, Edris B, Espinosa I, Zhu S, Li R, Montgomery KD, Marinelli RJ, Tibshirani R, Hastie T, Jablons DM, Rubin BP, Fletcher CD, West RB, van de Rijn M -
Sulf-2, a heparan sulfate endosulfatase, promotes human lung carcinogenesis.
Oncogene 2009 Lemjabbar-Alaoui H, van Zante A, Singer MS, Xue Q, Wang YQ, Tsay D, He B, Jablons DM, Rosen SD -
A translational approach to lung cancer research: From EGFRs to Wnt and cancer stem cells.
Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia 2009 Yagui-Beltrán A, Jablons DM -
Identification of hematein as a novel inhibitor of protein kinase CK2 from a natural product library.
BMC cancer 2009 Hung MS, Xu Z, Lin YC, Mao JH, Yang CT, Chang PJ, Jablons DM, You L -
Genomic prognostic models in early-stage lung cancer.
Clinical lung cancer 2009 Kratz JR, Jablons DM -
A multi-marker assay to distinguish malignant melanomas from benign nevi.
Proceedings of the National Academy of Sciences of the United States of America 2009 Kashani-Sabet M, Rangel J, Torabian S, Nosrati M, Simko J, Jablons DM, Moore DH, Haqq C, Miller JR, Sagebiel RW -
Respiratory Homeostasis and Exploitation of the Immune System for Lung Cancer Vaccines.
US oncology 2009 Yagui-Beltrán A, Coussens LM, Jablons DM -
Epidemiology of non-small cell lung cancer in Asian Americans: incidence patterns among six subgroups by nativity.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 2008 Raz DJ, Gomez SL, Chang ET, Kim JY, Keegan TH, Pham J, Kukreja J, Hiatt RA, Jablons DM -
The role of cancer stem cells in neoplasia of the lung: past, present and future.
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2008 Yagui-Beltrán A, He B, Jablons DM -
Inhibition of Hsp90 leads to cell cycle arrest and apoptosis in human malignant pleural mesothelioma.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 2008 Okamoto J, Mikami I, Tominaga Y, Kuchenbecker KM, Lin YC, Bravo DT, Clement G, Yagui-Beltran A, Ray MR, Koizumi K, He B, Jablons DM -
A multigene assay is prognostic of survival in patients with early-stage lung adenocarcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008 Raz DJ, Ray MR, Kim JY, He B, Taron M, Skrzypski M, Segal M, Gandara DR, Rosell R, Jablons DM -
Three-gene expression signature predicts survival in early-stage squamous cell carcinoma of the lung.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008 Skrzypski M, Jassem E, Taron M, Sanchez JJ, Mendez P, Rzyman W, Gulida G, Raz D, Jablons D, Provencio M, Massuti B, Chaib I, Perez-Roca L, Jassem J, Rosell R -
Nasopharyngeal carcinoma--review of the molecular mechanisms of tumorigenesis.
Head & neck 2008 Chou J, Lin YC, Kim J, You L, Xu Z, He B, Jablons DM -
mTOR mediates survival signals in malignant mesothelioma grown as tumor fragment spheroids.
American journal of respiratory cell and molecular biology 2008 Wilson SM, Barbone D, Yang TM, Jablons DM, Bueno R, Sugarbaker DJ, Nishimura SL, Gordon GJ, Broaddus VC -
Adjuvant treatment of stage IB NSCLC: the problem of stage subset heterogeneity.
Oncology (Williston Park, N.Y.) 2008 Calhoun R, Jablons D, Lau D, Gandara DR -
Translational research in glioblastoma multiforme: molecular criteria for patient selection.
Future oncology (London, England) 2008 Rosell R, de Las Peñas R, Balaña C, Santarpia M, Salazar F, de Aguirre I, Reguart N, Villa S, Wei J, Ramirez JL, Molina MA, Ramon y Cajal S, Jablons D, Taron M -
Unmet need in lung cancer: can vaccines bridge the gap?
Clinical lung cancer 2008 Kim J, Raz D, Jablons D -
Pharmacogenomic approaches to individualizing chemotherapy for non-small-cell lung cancer: current status and new directions.
Clinical lung cancer 2008 Gautschi O, Mack PC, Davies AM, Jablons DM, Rosell R, Gandara DR -
Optimal surgical management of Stage I non-small-cell lung cancer in an increasingly aging population: challenges and recent progress.
Expert review of respiratory medicine 2007 Yagui-Beltrán A, Jablons DM -
Epigenetic regulation of RhoB loss of expression in lung cancer.
BMC cancer 2007 Mazières J, Tovar D, He B, Nieto-Acosta J, Marty-Detraves C, Clanet C, Pradines A, Jablons D, Favre G -
Epigenetic alteration of the Wnt inhibitory factor-1 promoter occurs early in the carcinogenesis of Barrett's esophagus.
Cancer science 2007 Clément G, Guilleret I, He B, Yagui-Beltrán A, Lin YC, You L, Xu Z, Shi Y, Okamoto J, Benhattar J, Jablons D -
Squamous metaplasia amplifies pathologic epithelial-mesenchymal interactions in COPD patients.
The Journal of clinical investigation 2007 Araya J, Cambier S, Markovics JA, Wolters P, Jablons D, Hill A, Finkbeiner W, Jones K, Broaddus VC, Sheppard D, Barzcak A, Xiao Y, Erle DJ, Nishimura SL -
Targeting the Wnt signaling pathway with dishevelled and cisplatin synergistically suppresses mesothelioma cell growth.
Anticancer research 2007 Uematsu K, Seki N, Seto T, Isoe C, Tsukamoto H, Mikami I, You L, He B, Xu Z, Jablons DM, Eguchi K -
Inhibition of Wnt-2 and galectin-3 synergistically destabilizes beta-catenin and induces apoptosis in human colorectal cancer cells.
International journal of cancer 2007 Shi Y, He B, Kuchenbecker KM, You L, Xu Z, Mikami I, Yagui-Beltran A, Clement G, Lin YC, Okamoto J, Bravo DT, Jablons DM -
Roles of secreted frizzled-related proteins in cancer.
Acta pharmacologica Sinica 2007 Shi Y, He B, You L, Jablons DM -
Adjuvant chemotherapy of stage I non-small cell lung cancer in North America.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 2007 Gandara DR, Wakelee H, Calhoun R, Jablons D -
Diagnosis and treatment of bronchioloalveolar carcinoma.
Current opinion in pulmonary medicine 2007 Raz DJ, Kim JY, Jablons DM -
Impact of induction treatment on postoperative complications in the treatment of non-small cell lung cancer.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 2007 Brouchet L, Bauvin E, Marcheix B, Bigay-Game L, Renaud C, Berjaud J, Falcoze PE, Venissac N, Raz D, Jablons D, Mazières J, Dahan M -
EGFR expression and mutational analysis as a predictive test.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2007 Raz DJ, Jablons DM -
Natural history of stage I non-small cell lung cancer: implications for early detection.
Chest 2007 Raz DJ, Zell JA, Ou SH, Gandara DR, Anton-Culver H, Jablons DM -
Risk of cerebral metastases and neurological death after pathological complete response to neoadjuvant therapy for locally advanced nonsmall-cell lung cancer: clinical implications for the subsequent management of the brain.
Cancer 2007 Chen AM, Jahan TM, Jablons DM, Garcia J, Larson DA -
Update on the molecular biology of malignant mesothelioma.
Cancer 2007 Lee AY, Raz DJ, He B, Jablons DM -
Five-gene signature in non-small-cell lung cancer.
The New England journal of medicine 2007 Raz DJ, Jablons DM -
Wnt inhibitory factor-1 gene transfer inhibits melanoma cell growth.
Human gene therapy 2007 Lin YC, You L, Xu Z, He B, Yang CT, Chen JK, Mikami I, Clément G, Shi Y, Kuchenbecker K, Okamoto J, Kashani-Sabet M, Jablons DM -
Targeting the Wnt signaling pathway to treat Barrett's esophagus.
Expert opinion on therapeutic targets 2007 Clément G, Jablons DM, Benhattar J -
Wnt inhibitory factor inhibits lung cancer cell growth.
The Journal of thoracic and cardiovascular surgery 2007 Kim J, You L, Xu Z, Kuchenbecker K, Raz D, He B, Jablons D -
Clinical characteristics and survival of patients with surgically resected, incidentally detected lung cancer.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 2007 Raz DJ, Glidden DV, Odisho AY, Jablons DM -
Patterns of metastasis in human solid cancers.
Cancer treatment and research 2007 Leong SP, Cady B, Jablons DM, Garcia-Aguilar J, Reintgen D, Werner JA, Kitagawa Y -
Stathmin is overexpressed in malignant mesothelioma.
Anticancer research 2007 Kim JY, Harvard C, You L, Xu Z, Kuchenbecker K, Baehner R, Jablons D -
Misclassification of bronchioloalveolar carcinoma with cytologic diagnosis of lung cancer.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 2006 Raz DJ, Zell JA, Karnezis AN, Odisho A, Ignatius Ou SH, Anton-Culver H, Jablons DM -
Novel therapies targeting signaling pathways in lung cancer.
Thoracic surgery clinics 2006 Yagui-Beltrán A, He B, Raz D, Kim J, Jablons DM -
Tumor fluoro-2-deoxy-D-glucose avidity on positron emission tomographic scan predicts mortality in patients with early-stage pure and mixed bronchioloalveolar carcinoma.
The Journal of thoracic and cardiovascular surgery 2006 Raz DJ, Odisho AY, Franc BL, Jablons DM -
Current concepts in bronchioloalveolar carcinoma biology.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006 Raz DJ, He B, Rosell R, Jablons DM -
Clinical patterns of metastasis.
Cancer metastasis reviews 2006 Leong SP, Cady B, Jablons DM, Garcia-Aguilar J, Reintgen D, Jakub J, Pendas S, Duhaime L, Cassell R, Gardner M, Giuliano R, Archie V, Calvin D, Mensha L, Shivers S, Cox C, Werner JA, Kitagawa Y, … -
Phase 1/2 trial of autologous tumor mixed with an allogeneic GVAX vaccine in advanced-stage non-small-cell lung cancer.
Cancer gene therapy 2006 Nemunaitis J, Jahan T, Ross H, Sterman D, Richards D, Fox B, Jablons D, Aimi J, Lin A, Hege K -
Bronchioloalveolar carcinoma is not associated with younger age at diagnosis: an analysis of the SEER database.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 2006 Raz DJ, Jablons DM -
Bronchioloalveolar carcinoma: a review.
Clinical lung cancer 2006 Raz DJ, He B, Rosell R, Jablons DM -
Wnt inhibitory factor-1, a Wnt antagonist, is silenced by promoter hypermethylation in malignant pleural mesothelioma.
Biochemical and biophysical research communications 2006 Batra S, Shi Y, Kuchenbecker KM, He B, Reguart N, Mikami I, You L, Xu Z, Lin YC, Clément G, Jablons DM -
Future directions in the second-line treatment of non-small cell lung cancer.
Seminars in oncology 2006 Rosell R, Cecere F, Cognetti F, Cuello M, Sanchez JM, Taron M, Reguart N, Jablons D -
Wnt signaling activation and WIF-1 silencing in nasopharyngeal cancer cell lines.
Biochemical and biophysical research communications 2006 Lin YC, You L, Xu Z, He B, Mikami I, Thung E, Chou J, Kuchenbecker K, Kim J, Raz D, Yang CT, Chen JK, Jablons DM -
Wnt signaling in stem cells and lung cancer.
Ernst Schering Foundation symposium proceedings 2006 He B, Jablons DM -
Wnt-1 signal as a potential cancer therapeutic target.
Drug news & perspectives 2006 You L, Kim J, He B, Xu Z, McCormick F, Jablons DM -
The role of Wnt signaling in cancer and stem cells.
Future oncology (London, England) 2005 Reguart N, He B, Taron M, You L, Jablons DM, Rosell R -
Wnt2 as a new therapeutic target in malignant pleural mesothelioma.
International journal of cancer 2005 Mazieres J, You L, He B, Xu Z, Twogood S, Lee AY, Reguart N, Batra S, Mikami I, Jablons DM -
A novel in vitro model of human mesothelioma for studying tumor biology and apoptotic resistance.
American journal of respiratory cell and molecular biology 2005 Kim KU, Wilson SM, Abayasiriwardana KS, Collins R, Fjellbirkeland L, Xu Z, Jablons DM, Nishimura SL, Broaddus VC -
Activating mutations in the tyrosine kinase domain of the epidermal growth factor receptor are associated with improved survival in gefitinib-treated chemorefractory lung adenocarcinomas.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005 Taron M, Ichinose Y, Rosell R, Mok T, Massuti B, Zamora L, Mate JL, Manegold C, Ono M, Queralt C, Jahan T, Sanchez JJ, Sanchez-Ronco M, Hsue V, Jablons D, Sanchez JM, Moran T -
Inhibition of Wnt16 in human acute lymphoblastoid leukemia cells containing the t(1;19) translocation induces apoptosis.
Oncogene 2005 Mazieres J, You L, He B, Xu Z, Lee AY, Mikami I, McCormick F, Jablons DM -
Wnt signaling in stem cells and non-small-cell lung cancer.
Clinical lung cancer 2005 He B, Barg RN, You L, Xu Z, Reguart N, Mikami I, Batra S, Rosell R, Jablons DM -
Efficacy of Wnt-1 monoclonal antibody in sarcoma cells.
BMC cancer 2005 Mikami I, You L, He B, Xu Z, Batra S, Lee AY, Mazieres J, Reguart N, Uematsu K, Koizumi K, Jablons DM -
Wnt signaling in lung cancer.
Cancer letters 2005 Mazieres J, He B, You L, Xu Z, Jablons DM -
Blockade of Wnt-1 signaling induces apoptosis in human colorectal cancer cells containing downstream mutations.
Oncogene 2005 He B, Reguart N, You L, Mazieres J, Xu Z, Lee AY, Mikami I, McCormick F, Jablons DM -
Unusual thoracic problems in patients with malignancies: case 3. Carcinoid tumor of the thymus.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2005 Hansen EK, Krieg RM, Azar RJ, Jablons DM, Jahan TM, Zaloudek CJ -
Changes in radiographic abnormalities in organ donors: associations with lung transplantation.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 2005 McCowin MJ, Hall TS, Babcock WD, Solinger LL, Hall KW, Jablons DM -
Phase III intergroup study of talc poudrage vs talc slurry sclerosis for malignant pleural effusion.
Chest 2005 Dresler CM, Olak J, Herndon JE, Richards WG, Scalzetti E, Fleishman SB, Kernstine KH, Demmy T, Jablons DM, Kohman L, Daniel TM, Haasler GB, Sugarbaker DJ, Cooperative Groups Cancer and Leukemia Group … -
Secreted frizzled-related protein 4 is silenced by hypermethylation and induces apoptosis in beta-catenin-deficient human mesothelioma cells.
Cancer research 2005 He B, Lee AY, Dadfarmay S, You L, Xu Z, Reguart N, Mazieres J, Mikami I, McCormick F, Jablons DM -
Salmonella infection in an anterior mediastinal mass.
The Journal of thoracic and cardiovascular surgery 2005 Carter YM, Shagrun L, Klein H, Katz J, Jablons DM -
Dickkopf-1 antagonizes Wnt signaling independent of beta-catenin in human mesothelioma.
Biochemical and biophysical research communications 2004 Lee AY, He B, You L, Xu Z, Mazieres J, Reguart N, Mikami I, Batra S, Jablons DM -
Cloning and characterization of the promoter of human Wnt inhibitory factor-1.
Biochemical and biophysical research communications 2004 Reguart N, He B, Xu Z, You L, Lee AY, Mazieres J, Mikami I, Batra S, Rosell R, McCormick F, Jablons DM -
Expression of the secreted frizzled-related protein gene family is downregulated in human mesothelioma.
Oncogene 2004 Lee AY, He B, You L, Dadfarmay S, Xu Z, Mazieres J, Mikami I, McCormick F, Jablons DM -
Inhibition of Wnt-2-mediated signaling induces programmed cell death in non-small-cell lung cancer cells.
Oncogene 2004 You L, He B, Xu Z, Uematsu K, Mazieres J, Mikami I, Reguart N, Moody TW, Kitajewski J, McCormick F, Jablons DM -
An anti-Wnt-2 monoclonal antibody induces apoptosis in malignant melanoma cells and inhibits tumor growth.
Cancer research 2004 You L, He B, Xu Z, Uematsu K, Mazieres J, Fujii N, Mikami I, Reguart N, McIntosh JK, Kashani-Sabet M, McCormick F, Jablons DM -
Interleukin-4 receptor cytotoxin as therapy for human malignant pleural mesothelioma xenografts.
The Annals of thoracic surgery 2004 Beseth BD, Cameron RB, Leland P, You L, Varricchio F, Kreitman RJ, Maki RA, Jablons DM, Husain SR, Puri RK -
Wnt inhibitory factor-1 is silenced by promoter hypermethylation in human lung cancer.
Cancer research 2004 Mazieres J, He B, You L, Xu Z, Lee AY, Mikami I, Reguart N, Rosell R, McCormick F, Jablons DM -
Inhibition of Wnt-1 signaling induces apoptosis in beta-catenin-deficient mesothelioma cells.
Cancer research 2004 You L, He B, Uematsu K, Xu Z, Mazieres J, Lee A, McCormick F, Jablons DM -
Activity of the suppressor of cytokine signaling-3 promoter in human non-small-cell lung cancer.
Clinical lung cancer 2004 He B, You L, Xu Z, Mazieres J, Lee AY, Jablons DM -
Granulocyte-macrophage colony-stimulating factor gene-modified autologous tumor vaccines in non-small-cell lung cancer.
Journal of the National Cancer Institute 2004 Nemunaitis J, Sterman D, Jablons D, Smith JW, Fox B, Maples P, Hamilton S, Borellini F, Lin A, Morali S, Hege K -
Isolated pulmonary arteriovenous malformations requiring anatomic resection.
The Journal of thoracic and cardiovascular surgery 2004 Mann MJ, Kramer MJ, Hall TS, Anastassiou P, Katz J, Golden J, Jones K, Jablons DM -
A monoclonal antibody against Wnt-1 induces apoptosis in human cancer cells.
Neoplasia (New York, N.Y.) 2004 He B, You L, Uematsu K, Xu Z, Lee AY, Matsangou M, McCormick F, Jablons DM -
Future directions: oncolytic viruses.
Clinical lung cancer 2004 You L, He B, Xu Z, McCormick F, Jablons DM -
Malignant pleural mesothelioma: evaluation with CT, MR imaging, and PET.
Radiographics : a review publication of the Radiological Society of North America, Inc 2004 Wang ZJ, Reddy GP, Gotway MB, Higgins CB, Jablons DM, Ramaswamy M, Hawkins RA, Webb WR -
Mechanisms of and potential treatment strategies for metastatic disease in non-small cell lung cancer.
Seminars in thoracic and cardiovascular surgery 2004 Maslyar DJ, Jahan TM, Jablons DM -
Retrocardiac parathyroid tumor: a rare mediastinal site.
Surgery 2004 Corvera CU, Jablons D, Morita E, Clark OH -
SOCS-3 is frequently silenced by hypermethylation and suppresses cell growth in human lung cancer.
Proceedings of the National Academy of Sciences of the United States of America 2003 He B, You L, Uematsu K, Zang K, Xu Z, Lee AY, Costello JF, McCormick F, Jablons DM -
Activation of the Wnt pathway in non small cell lung cancer: evidence of dishevelled overexpression.
Oncogene 2003 Uematsu K, He B, You L, Xu Z, McCormick F, Jablons DM -
Intraoperative radiation therapy in the multimodality approach to upper aerodigestive tract cancer.
Surgical oncology clinics of North America 2003 Carter YM, Jablons DM, DuBois JB, Thomas CR -
Potential of mobile intraoperative radiotherapy technology.
Surgical oncology clinics of North America 2003 Goer DA, Musslewhite CW, Jablons DM -
1st International Lung Cancer Conference in Beijing, October 27-30, 2002.
Lung cancer (Amsterdam, Netherlands) 2003 Jablons DM, Cheng SJ, Carolyn Clary-Macy RN, Hirsch FR -
Integrin alphavbeta8-mediated activation of transforming growth factor-beta inhibits human airway epithelial proliferation in intact bronchial tissue.
The American journal of pathology 2003 Fjellbirkeland L, Cambier S, Broaddus VC, Hill A, Brunetta P, Dolganov G, Jablons D, Nishimura SL -
Wnt pathway activation in mesothelioma: evidence of Dishevelled overexpression and transcriptional activity of beta-catenin.
Cancer research 2003 Uematsu K, Kanazawa S, You L, He B, Xu Z, Li K, Peterlin BM, McCormick F, Jablons DM -
c-Kit is not expressed in malignant mesothelioma.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2003 Horvai AE, Li L, Xu Z, Kramer MJ, Jablons DM, Treseler PA -
Genomic alterations in human mesothelioma including high resolution mapping of common regions of DNA loss in chromosome arm 6q.
Anticancer research 2003 Jensen RH, Tiirikainen M, You L, Ginzinger D, He B, Uematsu K, Xu Z, Treseler P, McCormick F, Jablons DM -
Malignant mesothelioma does not demonstrate overexpression or gene amplification despite cytoplasmic immunohistochemical staining for c-Erb-B2.
Archives of pathology & laboratory medicine 2003 Horvai AE, Li L, Xu Z, Kramer MJ, Jablons DM, Treseler PA -
Cloning and characterization of a functional promoter of the human SOCS-3 gene.
Biochemical and biophysical research communications 2003 He B, You L, Uematsu K, Matsangou M, Xu Z, He M, McCormick F, Jablons DM -
Pericardial retraction sutures facilitate intrapericardial pneumonectomy.
The Journal of cardiovascular surgery 2003 Brevetti GR, Lin SC, Jablons DM, Napierkowski MT, Brevetti LS, Hall TS -
A comparison analysis of anti-tumor efficacy of adenoviral gene replacement therapy (p14ARF and p16INK4A) in human mesothelioma cells.
Anticancer research 2003 Yang CT, You L, Lin YC, Lin CL, Mccormick F, Jablons DM -
Emergent surgery for massive pulmonary embolism on the basis of clinical diagnosis.
Texas Heart Institute journal 2003 Brevetti GR, O'Brien B, Coomer CL, Hall TS, Brevetti LS, Jablons DM -
Contralateral tension pneumothorax during one-lung ventilation for lobectomy: diagnosis aided by fiberoptic bronchoscopy.
Anesthesia and analgesia 2002 Malik S, Shapiro WA, Jablons D, Katz JA -
Genomic copy number analysis of non-small cell lung cancer using array comparative genomic hybridization: implications of the phosphatidylinositol 3-kinase pathway.
Cancer research 2002 Massion PP, Kuo WL, Stokoe D, Olshen AB, Treseler PA, Chin K, Chen C, Polikoff D, Jain AN, Pinkel D, Albertson DG, Jablons DM, Gray JW -
Induction of apoptosis in mesothelioma cells by antisurvivin oligonucleotides.
Molecular cancer therapeutics 2002 Xia C, Xu Z, Yuan X, Uematsu K, You L, Li K, Li L, McCormick F, Jablons DM -
Aberrations in the fragile histidine triad (FHIT) gene in idiopathic pulmonary fibrosis.
Cancer research 2001 Uematsu K, Yoshimura A, Gemma A, Mochimaru H, Hosoya Y, Kunugi S, Matsuda K, Seike M, Kurimoto F, Takenaka K, Koizumi K, Fukuda Y, Tanaka S, Chin K, Jablons DM, Kudoh S -
p14(ARF) modulates the cytolytic effect of ONYX-015 in mesothelioma cells with wild-type p53.
Cancer research 2001 Yang CT, You L, Uematsu K, Yeh CC, McCormick F, Jablons DM -
Prostaglandin E2 and vasoactive intestinal peptide increase vascular endothelial cell growth factor mRNAs in lung cancer cells.
Lung cancer (Amsterdam, Netherlands) 2001 Casibang M, Purdom S, Jakowlew S, Neckers L, Zia F, Ben-Av P, Hla T, You L, Jablons DM, Moody TW -
Stage II (N1) lung cancer.
Chest surgery clinics of North America 2001 Choy O, Jahan T, Roach M, You L, Jablons D -
The impact of changes in radiographic abnormalities in organ donors on successful lung donation.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 2001 McCowin M, Hall TS, Babcock W, Solinger LL, Hall KW, Jablons D -
Expression sequence tag-specific full-length cDNA cloning: actin cDNAs.
Gene 2001 Xu Z, Jablons DM, Gruenert DC -
Giant tumors of the chest: preoperative embolization and resection.
The Journal of cardiovascular surgery 2000 Brevetti GR, Sasse KC, Khan JH, Wilson MW, Clary-Macy C, Brevetti LS, Hall TS, Jablons D -
Positron emission tomography with f18-fluorodeoxyglucose in the staging and preoperative evaluation of malignant pleural mesothelioma.
The Journal of thoracic and cardiovascular surgery 2000 Schneider DB, Clary-Macy C, Challa S, Sasse KC, Merrick SH, Hawkins R, Caputo G, Jablons D -
Adenovirus-mediated p14(ARF) gene transfer in human mesothelioma cells.
Journal of the National Cancer Institute 2000 Yang CT, You L, Yeh CC, Chang JW, Zhang F, McCormick F, Jablons DM -
ONYX-015 works synergistically with chemotherapy in lung cancer cell lines and primary cultures freshly made from lung cancer patients.
Cancer research 2000 You L, Yang CT, Jablons DM -
Pulmonary placental transmogrification: diagnosis and treatment.
The Journal of thoracic and cardiovascular surgery 1999 Brevetti GR, Clary-Macy C, Jablons DM -
Tumor-derived EMMPRIN (extracellular matrix metalloproteinase inducer) stimulates collagenase transcription through MAPK p38.
FEBS letters 1998 Lim M, Martinez T, Jablons D, Cameron R, Guo H, Toole B, Li JD, Basbaum C -
Giant solitary fibrous tumor of the pleura.
The Annals of thoracic surgery 1998 Khan JH, Rahman SB, Clary-Macy C, Kerlan RK, George TI, Hall TS, Jablons DM -
Resection and IORT followed by three-dimensional conformal radiotherapy with or without adjuvant chemotherapy for malignant mesothelioma.
Frontiers of radiation therapy and oncology 1997 Jablons DM, Roach M, Jahan T, Cameron RB -
The heimlich device in thoracic surgery.
Surgical technology international 1997 Key SP, Cameron RC, Jablons DM -
Interleukin 6 reduces lipoprotein lipase activity in adipose tissue of mice in vivo and in 3T3-L1 adipocytes: a possible role for interleukin 6 in cancer cachexia.
Cancer research 1992 Greenberg AS, Nordan RP, McIntosh J, Calvo JC, Scow RO, Jablons D -
IL-2-based immunotherapy alters circulating neutrophil Fc receptor expression and chemotaxis.
Journal of immunology (Baltimore, Md. : 1950) 1990 Jablons D, Bolton E, Mertins S, Rubin M, Pizzo P, Rosenberg SA, Lotze MT -
Interleukin-3 induces proliferation but not lymphokine activated killer activity from human and murine mononuclear cells.
European cytokine network 1990 Jablons DM, Donohue R, Kawakami Y, Young JD, Lotze MT -
Antitumor activity of recombinant interleukin 6 in mice.
The Journal of experimental medicine 1990 Mulé JJ, McIntosh JK, Jablons DM, Rosenberg SA -
In vivo induction of IL-6 by administration of exogenous cytokines and detection of de novo serum levels of IL-6 in tumor-bearing mice.
Journal of immunology (Baltimore, Md. : 1950) 1989 McIntosh JK, Jablons DM, Mulé JJ, Nordan RP, Rudikoff S, Lotze MT, Rosenberg SA -
Metastasectomy for soft tissue sarcoma. Further evidence for efficacy and prognostic indicators.
The Journal of thoracic and cardiovascular surgery 1989 Jablons D, Steinberg SM, Roth J, Pittaluga S, Rosenberg SA, Pass HI -
IL-6/IFN-beta-2 as a circulating hormone. Induction by cytokine administration in humans.
Journal of immunology (Baltimore, Md. : 1950) 1989 Jablons DM, Mulé JJ, McIntosh JK, Sehgal PB, May LT, Huang CM, Rosenberg SA, Lotze MT -
Induction of interferon-beta 2/interleukin-6 (IL-6) by cytokine administration and detection of circulating interleukin-6 in the tumor-bearing state.
Annals of the New York Academy of Sciences 1989 Jablons DM, McIntosh JK, Mulé JJ, Nordan RP, Rudikoff S, Lotze MT -
Derivation of cells with lytic activity against fresh and cultured tumors from human bone marrow.
The Journal of surgical research 1988 Jablons DM, Lotze MT