David Fox, MD
Associate Clinical Professor
Psychiatry - Fresno
School of Medicine
Grants and Projects
Show all (9) Hide
- University of Michigan Clinical Autoimmunity Center of Excellence, NIH, 2019-2024
- Training of Arthritis Research Scientists, NIH, 1976-2023
- Roles of soluble CD13 and its receptor in angiogenesis, monocyte recruitment, and joint inflammation, NIH, 2020-2021
- Proinflammatory and Autoantigenic Properties of a Novel Citrullinated Form of IL-6 in Rheumatoid Arthritis, NIH, 2018-2020
- University of Michigan Autoimmunity Center of Excellence, Clinical Research Progr, NIH, 2014-2019
- Unique Surface Structures on Synovial Cells, NIH, 1986-2012
- University of Michigan Rheumatic Diseases Research Core Center, NIH, 2001-2011
- Arthritis and Musculoskeletal Diseases Center, NIH, 1900-2002
- Unique Surface Structures on Rheumatoid Synovial T Cells, NIH, 1986-1991
Publications (136)
Top publication keywords:
Antigens, Differentiation, T-LymphocyteSiliconesAntirheumatic AgentsInterleukin-4CD13 AntigensRheumatologySynovial MembraneTh17 CellsAntigens, CDArthritis, RheumatoidFibroblastsScleroderma, DiffuseArthritis, ExperimentalInterleukin-17Scleroderma, Systemic
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Soluble CD13 induces inflammatory arthritis by activating the bradykinin receptor B1.
The Journal of clinical investigation 2022 Tsou PS, Lu C, Gurrea-Rubio M, Muraoka S, Campbell PL, Wu Q, Model EN, Lind ME, Vichaikul S, Mattichak MN, Brodie WD, Hervoso JL, Ory S, Amarista CI, Pervez R, Junginger L, Ali M, Hodish G, O'Mara MM,… -
Inhibition of bromodomain extraterminal histone readers alleviates skin fibrosis in experimental models of scleroderma.
JCI insight 2022 Vichaikul S, Gurrea-Rubio M, Amin MA, Campbell PL, Wu Q, Mattichak MN, Brodie WD, Palisoc PJ, Ali M, Muraoka S, Ruth JH, Model EN, Rohraff DM, Hervoso JL, Mao-Draayer Y, Fox DA, Khanna D, Sawalha AH, … -
Characterization of humoral response to COVID mRNA vaccines in multiple sclerosis patients on disease modifying therapies.
Vaccine 2021 Ali A, Dwyer D, Wu Q, Wang Q, Dowling CA, Fox DA, Khanna D, Poland GA, Mao-Draayer Y -
CD6 is a target for cancer immunotherapy.
JCI insight 2021 Ruth JH, Gurrea-Rubio M, Athukorala KS, Rasmussen SM, Weber DP, Randon PM, Gedert RJ, Lind ME, Amin MA, Campbell PL, Tsou PS, Mao-Draayer Y, Wu Q, Lanigan TM, Keshamouni VG, Singer NG, Lin F, Fox DA -
Correction to: Lymphocyte subset abnormalities in early diffuse cutaneous systemic sclerosis.
Arthritis research & therapy 2021 Fox DA, Lundy SK, Whitfield ML, Berrocal V, Campbell P, Rasmussen S, Ohara R, Stinson A, Gurrea-Rubio M, Wiewiora E, Spino C, Bush E, Furst D, Pillai S, Khanna D
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Interferon-stimulated GTPases in autoimmune and inflammatory diseases: promising role for the guanylate-binding protein (GBP) family.
Rheumatology (Oxford, England) 2021 Haque M, Siegel RJ, Fox DA, Ahmed S -
A conformation-selective monoclonal antibody against a small molecule-stabilised signalling-deficient form of TNF.
Nature communications 2021 Lightwood DJ, Munro RJ, Porter J, McMillan D, Carrington B, Turner A, Scott-Tucker A, Hickford ES, Schmidt A, Fox D, Maloney A, Ceska T, Bourne T, O'Connell J, Lawson ADG -
Structural insights into the disruption of TNF-TNFR1 signalling by small molecules stabilising a distorted TNF.
Nature communications 2021 McMillan D, Martinez-Fleites C, Porter J, Fox D, Davis R, Mori P, Ceska T, Carrington B, Lawson A, Bourne T, O'Connell J -
Lymphocyte subset abnormalities in early diffuse cutaneous systemic sclerosis.
Arthritis research & therapy 2021 Fox DA, Lundy SK, Whitfield ML, Berrocal V, Campbell P, Rasmussen S, Ohara R, Stinson A, Gurrea-Rubio M, Wiewiora E, Spino C, Bush E, Furst D, Pillai S, Khanna D -
Neutrophil-mediated carbamylation promotes articular damage in rheumatoid arthritis.
Science advances 2020 O'Neil LJ, Barrera-Vargas A, Sandoval-Heglund D, Merayo-Chalico J, Aguirre-Aguilar E, Aponte AM, Ruiz-Perdomo Y, Gucek M, El-Gabalawy H, Fox DA, Katz JD, Kaplan MJ, Carmona-Rivera C -
Safety and efficacy of abatacept in early diffuse cutaneous systemic sclerosis (ASSET): open-label extension of a phase 2, double-blind randomised trial.
The Lancet. Rheumatology 2020 Chung L, Spino C, McLain R, Johnson SR, Denton CP, Molitor JA, Steen VD, Lafyatis R, Simms RW, Kafaja S, Frech TM, Hsu V, Domsic RT, Pope JE, Gordon JK, Mayes MD, Sandorfi N, Hant FN, Bernstein EJ, … -
Attenuation of Murine Collagen-Induced Arthritis by Targeting CD6.
Arthritis & rheumatology (Hoboken, N.J.) 2020 Li Y, Ruth JH, Rasmussen SM, Athukorala KS, Weber DP, Amin MA, Campbell PL, Singer NG, Fox DA, Lin F -
Neutrophil extracellular traps mediate articular cartilage damage and enhance cartilage component immunogenicity in rheumatoid arthritis.
JCI insight 2020 Carmona-Rivera C, Carlucci PM, Goel RR, James E, Brooks SR, Rims C, Hoffmann V, Fox DA, Buckner JH, Kaplan MJ -
HGT in the human and skin commensal Malassezia: A bacterially derived flavohemoglobin is required for NO resistance and host interaction.
Proceedings of the National Academy of Sciences of the United States of America 2020 Ianiri G, Coelho MA, Ruchti F, Sparber F, McMahon TJ, Fu C, Bolejack M, Donovan O, Smutney H, Myler P, Dietrich F, Fox D, LeibundGut-Landmann S, Heitman J -
Real time visualization of cancer cell death, survival and proliferation using fluorochrome-transfected cells in an IncuCyte® imaging system.
Journal of biological methods 2020 Lanigan TM, Rasmussen SM, Weber DP, Athukorala KS, Campbell PL, Fox DA, Ruth JH -
IRAK4 inhibition: a promising strategy for treating RA joint inflammation and bone erosion.
Cellular & molecular immunology 2020 Umar S, Palasiewicz K, Van Raemdonck K, Volin MV, Romay B, Amin MA, Zomorrodi RK, Arami S, Gonzalez M, Rao V, Zanotti B, Fox DA, Sweiss N, Shahrara S -
Siponimod enriches regulatory T and B lymphocytes in secondary progressive multiple sclerosis.
JCI insight 2020 Wu Q, Mills EA, Wang Q, Dowling CA, Fisher C, Kirch B, Lundy SK, Fox DA, Mao-Draayer Y, AMS04 Study Group -
CD13/Aminopeptidase N Is a Potential Therapeutic Target for Inflammatory Disorders.
Journal of immunology (Baltimore, Md. : 1950) 2020 Lu C, Amin MA, Fox DA -
Georgia Abortion Law and Our Commitment to Patients.
Arthritis & rheumatology (Hoboken, N.J.) 2019 Craft JE, Crow MK, Lockshin MD, Salmon JE, Diamond B, Elkon KB, Flood J, Fox DA, Gabriel SE, Gilkeson GS, Hahn BH, Hardin J, Koopman WJ, Seaman WE, Wofsy D, Sergent JS, Uknis AB, Weinblatt ME -
Pharmacological inhibition of TAK1, with the selective inhibitor takinib, alleviates clinical manifestation of arthritis in CIA mice.
Arthritis research & therapy 2019 Scarneo SA, Eibschutz LS, Bendele PJ, Yang KW, Totzke J, Hughes P, Fox DA, Haystead TAJ -
Abatacept in Early Diffuse Cutaneous Systemic Sclerosis: Results of a Phase II Investigator-Initiated, Multicenter, Double-Blind, Randomized, Placebo-Controlled Trial.
Arthritis & rheumatology (Hoboken, N.J.) 2019 Khanna D, Spino C, Johnson S, Chung L, Whitfield ML, Denton CP, Berrocal V, Franks J, Mehta B, Molitor J, Steen VD, Lafyatis R, Simms RW, Gill A, Kafaja S, Frech TM, Hsu V, Domsic RT, Pope JE, Gordon … -
Harnessing calcineurin-FK506-FKBP12 crystal structures from invasive fungal pathogens to develop antifungal agents.
Nature communications 2019 Juvvadi PR, Fox D, Bobay BG, Hoy MJ, Gobeil SMC, Venters RA, Chang Z, Lin JJ, Averette AF, Cole DC, Barrington BC, Wheaton JD, Ciofani M, Trzoss M, Li X, Lee SC, Chen YL, Mutz M, Spicer LD, Schumacher… -
Patterns of glucocorticoid prescribing and provider-level variation in a commercially insured incident rheumatoid arthritis population: A retrospective cohort study.
Seminars in arthritis and rheumatism 2019 Wallace BI, Lin P, Kamdar N, Noureldin M, Hayward R, Fox DA, Curtis JR, Saag KG, Waljee AK -
Absence of complement component 3 does not prevent classical pathway-mediated hemolysis.
Blood advances 2019 Zhang L, Dai Y, Huang P, Saunders TL, Fox DA, Xu J, Lin F -
Citrullinated Inhibitor of DNA Binding 1 Is a Novel Autoantigen in Rheumatoid Arthritis.
Arthritis & rheumatology (Hoboken, N.J.) 2019 Ohara RA, Edhayan G, Rasmussen SM, Isozaki T, Remmer HA, Lanigan TM, Campbell PL, Urquhart AG, Lawton JN, Chung KC, Fox DA, Ruth JH -
Macrophages are the primary effector cells in IL-7-induced arthritis.
Cellular & molecular immunology 2019 Kim SJ, Chang HJ, Volin MV, Umar S, Van Raemdonck K, Chevalier A, Palasiewicz K, Christman JW, Volkov S, Arami S, Maz M, Mehta A, Zomorrodi RK, Fox DA, Sweiss N, Shahrara S -
Angiogenic and Arthritogenic Properties of the Soluble Form of CD13.
Journal of immunology (Baltimore, Md. : 1950) 2019 Du Y, Lu C, Morgan RL, Stinson WA, Campbell PL, Cealey E, Fu W, Lepore NJ, Hervoso JL, Cui H, Urquhart AG, Lawton JN, Chung KC, Fox DA, Amin MA -
Design and Synthesis of Selective Phosphodiesterase 4D (PDE4D) Allosteric Inhibitors for the Treatment of Fragile X Syndrome and Other Brain Disorders.
Journal of medicinal chemistry 2019 Gurney ME, Nugent RA, Mo X, Sindac JA, Hagen TJ, Fox D, O'Donnell JM, Zhang C, Xu Y, Zhang HT, Groppi VE, Bailie M, White RE, Romero DL, Vellekoop AS, Walker JR, Surman MD, Zhu L, Campbell RF -
5-Aryl-1,3,4-oxadiazol-2-ylthioalkanoic Acids: A Highly Potent New Class of Inhibitors of Rho/Myocardin-Related Transcription Factor (MRTF)/Serum Response Factor (SRF)-Mediated Gene Transcription as Potential Antifibrotic Agents for Scleroderma.
Journal of medicinal chemistry 2019 Kahl DJ, Hutchings KM, Lisabeth EM, Haak AJ, Leipprandt JR, Dexheimer T, Khanna D, Tsou PS, Campbell PL, Fox DA, Wen B, Sun D, Bailie M, Neubig RR, Larsen SD -
Identification of Pirin as a Molecular Target of the CCG-1423/CCG-203971 Series of Antifibrotic and Antimetastatic Compounds.
ACS pharmacology & translational science 2019 Lisabeth EM, Kahl D, Gopallawa I, Haynes SE, Misek SA, Campbell PL, Dexheimer TS, Khanna D, Fox DA, Jin X, Martin BR, Larsen SD, Neubig RR -
Inhibition of EZH2 prevents fibrosis and restores normal angiogenesis in scleroderma.
Proceedings of the National Academy of Sciences of the United States of America 2019 Tsou PS, Campbell P, Amin MA, Coit P, Miller S, Fox DA, Khanna D, Sawalha AH -
Memory enhancing effects of BPN14770, an allosteric inhibitor of phosphodiesterase-4D, in wild-type and humanized mice.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2018 Zhang C, Xu Y, Chowdhary A, Fox D, Gurney ME, Zhang HT, Auerbach BD, Salvi RJ, Yang M, Li G, O'Donnell JM -
Transcriptional Profiling of Synovial Macrophages Using Minimally Invasive Ultrasound-Guided Synovial Biopsies in Rheumatoid Arthritis.
Arthritis & rheumatology (Hoboken, N.J.) 2018 Mandelin AM, Homan PJ, Shaffer AM, Cuda CM, Dominguez ST, Bacalao E, Carns M, Hinchcliff M, Lee J, Aren K, Thakrar A, Montgomery AB, Bridges SL, Bathon JM, Atkinson JP, Fox DA, Matteson EL, Buckley CD… -
Role of Complement in a Rat Model of Paclitaxel-Induced Peripheral Neuropathy.
Journal of immunology (Baltimore, Md. : 1950) 2018 Xu J, Zhang L, Xie M, Li Y, Huang P, Saunders TL, Fox DA, Rosenquist R, Lin F -
Response to comment on "Synovial fibroblast-neutrophil interactions promote pathogenic adaptive immunity in rheumatoid arthritis".
Science immunology 2018 Carmona-Rivera C, Bicker KL, Thompson PR, Buckner JH, Robinson WH, Fox DA, Kaplan MJ -
The role of CD6 in autoimmune diseases.
Cellular & molecular immunology 2018 Fox DA -
Clinical and experimental evidence for targeting CD6 in immune-based disorders.
Autoimmunity reviews 2018 Consuegra-Fernández M, Lin F, Fox DA, Lozano F -
Targeting CD6 for the treatment of experimental autoimmune uveitis.
Journal of autoimmunity 2018 Zhang L, Li Y, Qiu W, Bell BA, Dvorina N, Baldwin WM, Singer N, Kern T, Caspi RR, Fox DA, Lin F -
A unique role for galectin-9 in angiogenesis and inflammatory arthritis.
Arthritis research & therapy 2018 O'Brien MJ, Shu Q, Stinson WA, Tsou PS, Ruth JH, Isozaki T, Campbell PL, Ohara RA, Koch AE, Fox DA, Amin MA -
IL-11 facilitates a novel connection between RA joint fibroblasts and endothelial cells.
Angiogenesis 2018 Elshabrawy HA, Volin MV, Essani AB, Chen Z, McInnes IB, Van Raemdonck K, Palasiewicz K, Arami S, Gonzalez M, Ashour HM, Kim SJ, Zhou G, Fox DA, Shahrara S -
Establishing clinical severity for PROMIS® measures in adult patients with rheumatic diseases.
Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation 2017 Nagaraja V, Mara C, Khanna PP, Namas R, Young A, Fox DA, Laing T, McCune WJ, Dodge C, Rizzo D, Almackenzie M, Khanna D -
Takinib, a Selective TAK1 Inhibitor, Broadens the Therapeutic Efficacy of TNF-α Inhibition for Cancer and Autoimmune Disease.
Cell chemical biology 2017 Totzke J, Gurbani D, Raphemot R, Hughes PF, Bodoor K, Carlson DA, Loiselle DR, Bera AK, Eibschutz LS, Perkins MM, Eubanks AL, Campbell PL, Fox DA, Westover KD, Haystead TAJ, Derbyshire ER -
CD318 is a ligand for CD6.
Proceedings of the National Academy of Sciences of the United States of America 2017 Enyindah-Asonye G, Li Y, Ruth JH, Spassov DS, Hebron KE, Zijlstra A, Moasser MM, Wang B, Singer NG, Cui H, Ohara RA, Rasmussen SM, Fox DA, Lin F -
Transforming growth factor β activated kinase 1: a potential therapeutic target for rheumatic diseases.
Rheumatology (Oxford, England) 2017 Fechtner S, Fox DA, Ahmed S -
Seven-Year Outcomes of the Silicone Arthroplasty in Rheumatoid Arthritis Prospective Cohort Study.
Arthritis care & research 2017 Chung KC, Kotsis SV, Burns PB, Burke FD, Wilgis EFS, Fox DA, Kim HM -
Synovial cellular and molecular markers in rheumatoid arthritis.
Seminars in immunopathology 2017 Asif Amin M, Fox DA, Ruth JH -
Synovial fibroblast-neutrophil interactions promote pathogenic adaptive immunity in rheumatoid arthritis.
Science immunology 2017 Carmona-Rivera C, Carlucci PM, Moore E, Lingampalli N, Uchtenhagen H, James E, Liu Y, Bicker KL, Wahamaa H, Hoffmann V, Catrina AI, Thompson P, Buckner JH, Robinson WH, Fox DA, Kaplan MJ -
Pharmacokinetic optimitzation of CCG-203971: Novel inhibitors of the Rho/MRTF/SRF transcriptional pathway as potential antifibrotic therapeutics for systemic scleroderma.
Bioorganic & medicinal chemistry letters 2017 Hutchings KM, Lisabeth EM, Rajeswaran W, Wilson MW, Sorenson RJ, Campbell PL, Ruth JH, Amin A, Tsou PS, Leipprandt JR, Olson SR, Wen B, Zhao T, Sun D, Khanna D, Fox DA, Neubig RR, Larsen SD -
CD6 as a potential target for treating multiple sclerosis.
Proceedings of the National Academy of Sciences of the United States of America 2017 Li Y, Singer NG, Whitbred J, Bowen MA, Fox DA, Lin F -
DEK-targeting DNA aptamers as therapeutics for inflammatory arthritis.
Nature communications 2017 Mor-Vaknin N, Saha A, Legendre M, Carmona-Rivera C, Amin MA, Rabquer BJ, Gonzales-Hernandez MJ, Jorns J, Mohan S, Yalavarthi S, Pai DA, Angevine K, Almburg SJ, Knight JS, Adams BS, Koch AE, Fox DA, … -
TLRs, future potential therapeutic targets for RA.
Autoimmunity reviews 2016 Elshabrawy HA, Essani AE, Szekanecz Z, Fox DA, Shahrara S -
Histone Deacetylase 5 Is Overexpressed in Scleroderma Endothelial Cells and Impairs Angiogenesis via Repression of Proangiogenic Factors.
Arthritis & rheumatology (Hoboken, N.J.) 2016 Tsou PS, Wren JD, Amin MA, Schiopu E, Fox DA, Khanna D, Sawalha AH -
Localization, Shedding, Regulation and Function of Aminopeptidase N/CD13 on Fibroblast like Synoviocytes.
PloS one 2016 Morgan RL, Behbahani-Nejad N, Endres J, Amin MA, Lepore NJ, Du Y, Urquhart A, Chung KC, Fox DA -
Inflammatory properties of inhibitor of DNA binding 1 secreted by synovial fibroblasts in rheumatoid arthritis.
Arthritis research & therapy 2016 Edhayan G, Ohara RA, Stinson WA, Amin MA, Isozaki T, Ha CM, Haines GK, Morgan R, Campbell PL, Arbab AS, Friday SC, Fox DA, Ruth JH -
Phospholipase D enzymes facilitate IL-17- and TNFα-induced expression of proinflammatory genes in rheumatoid arthritis synovial fibroblasts (RASF).
Immunology letters 2016 Friday SC, Fox DA -
Activation of the Thromboxane A2 Receptor by 8-Isoprostane Inhibits the Pro-Angiogenic Effect of Vascular Endothelial Growth Factor in Scleroderma.
The Journal of investigative dermatology 2015 Tsou PS, Amin MA, Campbell PL, Zakhem G, Balogh B, Edhayan G, Ohara RA, Schiopu E, Khanna D, Koch AE, Fox DA -
Citrullination: A Specific Target for the Autoimmune Response in Rheumatoid Arthritis.
Journal of immunology (Baltimore, Md. : 1950) 2015 Fox DA -
Killer B lymphocytes and their fas ligand positive exosomes as inducers of immune tolerance.
Frontiers in immunology 2015 Lundy SK, Klinker MW, Fox DA -
The incidence of upper and lower extremity surgery for rheumatoid arthritis among Medicare beneficiaries.
The Journal of bone and joint surgery. American volume 2015 Waljee J, Zhong L, Baser O, Yuce H, Fox DA, Chung KC -
Loss of SH3 domain-binding protein 2 function suppresses bone destruction in tumor necrosis factor-driven and collagen-induced arthritis in mice.
Arthritis & rheumatology (Hoboken, N.J.) 2015 Mukai T, Gallant R, Ishida S, Kittaka M, Yoshitaka T, Fox DA, Morita Y, Nishida K, Rottapel R, Ueki Y -
Variation in rheumatoid hand and wrist surgery among medicare beneficiaries: a population-based cohort study.
The Journal of rheumatology 2015 Zhong L, Chung KC, Baser O, Fox DA, Yuce H, Waljee JF -
Expression and function of aminopeptidase N/CD13 produced by fibroblast-like synoviocytes in rheumatoid arthritis: role of CD13 in chemotaxis of cytokine-activated T cells independent of enzymatic activity.
Arthritis & rheumatology (Hoboken, N.J.) 2015 Morgan R, Endres J, Behbahani-Nejad N, Phillips K, Ruth JH, Friday SC, Edhayan G, Lanigan T, Urquhart A, Chung KC, Fox DA -
Current and future approaches to the treatment of immunologic diseases: new targets and new therapeutic agents.
Translational research : the journal of laboratory and clinical medicine 2014 Fox DA -
Patient expectations and long-term outcomes in rheumatoid arthritis patients: results from the SARA (Silicone Arthroplasty in Rheumatoid Arthritis) study.
Clinical rheumatology 2014 Chung KC, Nellans KW, Burns PB, Wilgis EF, Burke FD, Fox DA, Kim HM -
SH3BP2 gain-of-function mutation exacerbates inflammation and bone loss in a murine collagen-induced arthritis model.
PloS one 2014 Mukai T, Gallant R, Ishida S, Yoshitaka T, Kittaka M, Nishida K, Fox DA, Morita Y, Ueki Y -
Discovery of triazines as selective PDE4B versus PDE4D inhibitors.
Bioorganic & medicinal chemistry letters 2014 Hagen TJ, Mo X, Burgin AB, Fox D, Zhang Z, Gurney ME -
Synovial phenotypes in rheumatoid arthritis correlate with response to biologic therapeutics.
Arthritis research & therapy 2014 Dennis G, Holweg CT, Kummerfeld SK, Choy DF, Setiadi AF, Hackney JA, Haverty PM, Gilbert H, Lin WY, Diehl L, Fischer S, Song A, Musselman D, Klearman M, Gabay C, Kavanaugh A, Endres J, Fox DA, Martin … -
Targeting the myofibroblast genetic switch: inhibitors of myocardin-related transcription factor/serum response factor-regulated gene transcription prevent fibrosis in a murine model of skin injury.
The Journal of pharmacology and experimental therapeutics 2014 Haak AJ, Tsou PS, Amin MA, Ruth JH, Campbell P, Fox DA, Khanna D, Larsen SD, Neubig RR -
The histone-fold complex MHF is remodeled by FANCM to recognize branched DNA and protect genome stability.
Cell research 2014 Fox D, Yan Z, Ling C, Zhao Y, Lee DY, Fukagawa T, Yang W, Wang W -
Human B Cell-Derived Lymphoblastoid Cell Lines Constitutively Produce Fas Ligand and Secrete MHCII(+)FasL(+) Killer Exosomes.
Frontiers in immunology 2014 Klinker MW, Lizzio V, Reed TJ, Fox DA, Lundy SK -
T cell subsets and their role in the pathogenesis of rheumatic disease.
Current opinion in rheumatology 2014 Gizinski AM, Fox DA -
Lipoic acid plays a role in scleroderma: insights obtained from scleroderma dermal fibroblasts.
Arthritis research & therapy 2014 Tsou PS, Balogh B, Pinney AJ, Zakhem G, Lozier A, Amin MA, Stinson WA, Schiopu E, Khanna D, Fox DA, Koch AE -
Plasma CXCL9 elevations correlate with chronic GVHD diagnosis.
Blood 2013 Kitko CL, Levine JE, Storer BE, Chai X, Fox DA, Braun TM, Couriel DR, Martin PJ, Flowers ME, Hansen JA, Chang L, Conlon M, Fiema BJ, Morgan R, Pongtornpipat P, Lamiman K, Ferrara JL, Lee SJ, Paczesny … -
Noxa in rheumatic diseases: present understanding and future impact.
Rheumatology (Oxford, England) 2013 Cottier KE, Fogle EM, Fox DA, Ahmed S -
Voriconazole-induced periostitis causing arthralgias mimicking a flare of granulomatosis with polyangiitis.
Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases 2013 Gladue HS, Fox DA -
Porphyromonas gingivalis oral infection exacerbates the development and severity of collagen-induced arthritis.
Arthritis research & therapy 2013 Marchesan JT, Gerow EA, Schaff R, Taut AD, Shin SY, Sugai J, Brand D, Burberry A, Jorns J, Lundy SK, Nuñez G, Fox DA, Giannobile WV -
The effect of swan neck and boutonniere deformities on the outcome of silicone metacarpophalangeal joint arthroplasty in rheumatoid arthritis.
Plastic and reconstructive surgery 2013 Chetta M, Burns PB, Kim HM, Burke FD, Wilgis EFS, Fox DA, Chung KC -
Interleukin-5 supports the expansion of fas ligand-expressing killer B cells that induce antigen-specific apoptosis of CD4(+) T cells and secrete interleukin-10.
PloS one 2013 Klinker MW, Reed TJ, Fox DA, Lundy SK -
Top3β is an RNA topoisomerase that works with fragile X syndrome protein to promote synapse formation.
Nature neuroscience 2013 Xu D, Shen W, Guo R, Xue Y, Peng W, Sima J, Yang J, Sharov A, Srikantan S, Yang J, Fox D, Qian Y, Martindale JL, Piao Y, Machamer J, Joshi SR, Mohanty S, Shaw AC, Lloyd TE, Brown GW, Ko MS, Gorospe M,… -
Metacarpophalangeal implant surgery: time for a randomized clinical trial? Reply.
Arthritis care & research 2013 Kim HM, Burns PB, Fox DA, Chung KC, Burke FD, Wilgis EF -
NETs are a source of citrullinated autoantigens and stimulate inflammatory responses in rheumatoid arthritis.
Science translational medicine 2013 Khandpur R, Carmona-Rivera C, Vivekanandan-Giri A, Gizinski A, Yalavarthi S, Knight JS, Friday S, Li S, Patel RM, Subramanian V, Thompson P, Chen P, Fox DA, Pennathur S, Kaplan MJ -
Citrullinated calreticulin potentiates rheumatoid arthritis shared epitope signaling.
Arthritis and rheumatism 2013 Ling S, Cline EN, Haug TS, Fox DA, Holoshitz J -
The roles of IFN-γ versus IL-17 in pathogenic effects of human Th17 cells on synovial fibroblasts.
Modern rheumatology 2013 Kato H, Endres J, Fox DA -
Regulation of Th17 maturation by interleukin 4.
Critical reviews in immunology 2013 Cooney LA, Fox DA -
Reflecting on early arthritis.
The Journal of rheumatology 2012 Kovacs D, Torralba KD, Fox DA, Solomon DH, Panush RS -
Long-term followup for rheumatoid arthritis patients in a multicenter outcomes study of silicone metacarpophalangeal joint arthroplasty.
Arthritis care & research 2012 Chung KC, Burns PB, Kim HM, Burke FD, Wilgis EF, Fox DA -
Kinase inhibition--a new approach to the treatment of rheumatoid arthritis.
The New England journal of medicine 2012 Fox DA -
Treg cells to the rescue.
Arthritis and rheumatism 2012 Fox DA -
A ubiquitin-binding protein, FAAP20, links RNF8-mediated ubiquitination to the Fanconi anemia DNA repair network.
Molecular cell 2012 Yan Z, Guo R, Paramasivam M, Shen W, Ling C, Fox D, Wang Y, Oostra AB, Kuehl J, Lee DY, Takata M, Hoatlin ME, Schindler D, Joenje H, de Winter JP, Li L, Seidman MM, Wang W -
Epilogue: how will we care for patients with early arthritis?
Rheumatic diseases clinics of North America 2012 Panush RS, Quismorio FP, Fox DA -
Sensitivity and resistance to regulation by IL-4 during Th17 maturation.
Journal of immunology (Baltimore, Md. : 1950) 2011 Cooney LA, Towery K, Endres J, Fox DA -
Properties of the International Classification for Functioning, Disability and Health in assessing hand outcomes in patients with rheumatoid arthritis.
Journal of rehabilitation medicine 2011 Chung KC, Burns PB, Reichert HA, Fox DA, Burke FD, Wilgis EF, Regan M, Kim HM -
A polymorphism in the interleukin-4 receptor affects the ability of interleukin-4 to regulate Th17 cells: a possible immunoregulatory mechanism for genetic control of the severity of rheumatoid arthritis.
Arthritis research & therapy 2011 Wallis SK, Cooney LA, Endres JL, Lee MJ, Ryu J, Somers EC, Fox DA -
Advances in the medical treatment of rheumatoid arthritis.
Hand clinics 2011 Kahlenberg JM, Fox DA -
Historical perspective on the etiology of rheumatoid arthritis.
Hand clinics 2011 Entezami P, Fox DA, Clapham PJ, Chung KC -
Are Th17 cells an appropriate new target in the treatment of rheumatoid arthritis?
Clinical and translational science 2010 Kato H, Fox DA -
Rif1 provides a new DNA-binding interface for the Bloom syndrome complex to maintain normal replication.
The EMBO journal 2010 Xu D, Muniandy P, Leo E, Yin J, Thangavel S, Shen X, Ii M, Agama K, Guo R, Fox D, Meetei AR, Wilson L, Nguyen H, Weng NP, Brill SJ, Li L, Vindigni A, Pommier Y, Seidman M, Wang W -
Pharmacotherapy: concepts of pathogenesis and emerging treatments. Co-stimulation and T cells as therapeutic targets.
Best practice & research. Clinical rheumatology 2010 Gizinski AM, Fox DA, Sarkar S -
Validity and responsiveness of the Michigan Hand Questionnaire in patients with rheumatoid arthritis: a multicenter, international study.
Arthritis care & research 2010 Waljee JF, Chung KC, Kim HM, Burns PB, Burke FD, Wilgis EF, Fox DA -
Cell-cell interactions in rheumatoid arthritis synovium.
Rheumatic diseases clinics of North America 2010 Fox DA, Gizinski A, Morgan R, Lundy SK -
Involvement of the renin-angiotensin system in the development of vascular damage in a rat model of arthritis: effect of angiotensin receptor blockers.
Arthritis and rheumatism 2010 Sakuta T, Morita Y, Satoh M, Fox DA, Kashihara N -
Preface: rheumatoid arthritis--halfway there.
Rheumatic diseases clinics of North America 2010 Fox DA -
Targeting IL-17 and Th17 cells in rheumatoid arthritis.
Rheumatic diseases clinics of North America 2010 Sarkar S, Fox DA -
Differences between the United States and the United Kingdom in the treatment of rheumatoid arthritis: analyses from a hand arthroplasty trial.
Clinical rheumatology 2010 Chung KC, Kotsis SV, Fox DA, Regan M, Burke FD, Wilgis EF, Kim HM -
RecQL5 promotes genome stabilization through two parallel mechanisms--interacting with RNA polymerase II and acting as a helicase.
Molecular and cellular biology 2010 Islam MN, Fox D, Guo R, Enomoto T, Wang W -
Outcomes of silicone arthroplasty for rheumatoid metacarpophalangeal joints stratified by fingers.
The Journal of hand surgery 2009 Chung KC, Kotsis SV, Wilgis EF, Fox DA, Regan M, Kim HM, Burke FD -
Regulation of pathogenic IL-17 responses in collagen-induced arthritis: roles of endogenous interferon-gamma and IL-4.
Arthritis research & therapy 2009 Sarkar S, Cooney LA, White P, Dunlop DB, Endres J, Jorns JM, Wasco MJ, Fox DA -
Reduced Fas ligand-expressing splenic CD5+ B lymphocytes in severe collagen-induced arthritis.
Arthritis research & therapy 2009 Lundy SK, Fox DA -
A prospective study comparing outcomes after reconstruction in rheumatoid arthritis patients with severe ulnar drift deformities.
Plastic and reconstructive surgery 2009 Chung KC, Burke FD, Wilgis EFS, Regan M, Kim HM, Fox DA -
A multicenter clinical trial in rheumatoid arthritis comparing silicone metacarpophalangeal joint arthroplasty with medical treatment.
The Journal of hand surgery 2009 Chung KC, Burns PB, Wilgis EF, Burke FD, Regan M, Kim HM, Fox DA -
The future of ILAR.
Clinical rheumatology 2009 Fox DA -
Unity in the field of rheumatology: the role of the ACR.
Arthritis and rheumatism 2009 Fox DA -
Etanercept-associated pulmonary granulomatous inflammation in patients with rheumatoid arthritis.
The Journal of rheumatology 2008 Ognenovski VM, Ojo TC, Fox DA -
Regulatory T cells in rheumatoid arthritis.
Current rheumatology reports 2008 Sarkar S, Fox DA -
CD19+CD5+ B cells in primary IgA nephropathy.
Journal of the American Society of Nephrology : JASN 2008 Yuling H, Ruijing X, Xiang J, Yanping J, Lang C, Li L, Dingping Y, Xinti T, Jingyi L, Zhiqing T, Yongyi B, Bing X, Xinxing W, Youxin J, Fox DA, Lundy SK, Guohua D, Jinquan T -
Th17 cells in human disease.
Immunological reviews 2008 Tesmer LA, Lundy SK, Sarkar S, Fox DA -
High-throughput profiling of ion channel activity in primary human lymphocytes.
Analytical chemistry 2008 Estes DJ, Memarsadeghi S, Lundy SK, Marti F, Mikol DD, Fox DA, Mayer M -
Interactions of T cells with fibroblast-like synoviocytes: role of the B7 family costimulatory ligand B7-H3.
Journal of immunology (Baltimore, Md. : 1950) 2008 Tran CN, Thacker SG, Louie DM, Oliver J, White PT, Endres JL, Urquhart AG, Chung KC, Fox DA -
The past and the future of Arthritis & Rheumatism: a view from the American College of Rheumatology.
Arthritis and rheumatism 2008 Fox DA -
Molecular interactions between T cells and fibroblast-like synoviocytes: role of membrane tumor necrosis factor-alpha on cytokine-activated T cells.
The American journal of pathology 2007 Tran CN, Lundy SK, White PT, Endres JL, Motyl CD, Gupta R, Wilke CM, Shelden EA, Chung KC, Urquhart AG, Fox DA -
Fluvastatin reverses endothelial dysfunction and increased vascular oxidative stress in rat adjuvant-induced arthritis.
Arthritis and rheumatism 2007 Haruna Y, Morita Y, Yada T, Satoh M, Fox DA, Kashihara N -
Presentation of arthritogenic peptide to antigen-specific T cells by fibroblast-like synoviocytes.
Arthritis and rheumatism 2007 Tran CN, Davis MJ, Tesmer LA, Endres JL, Motyl CD, Smuda C, Somers EC, Chung KC, Urquhart AG, Lundy SK, Kovats S, Fox DA -
Regulatory T cell defects in rheumatoid arthritis.
Arthritis and rheumatism 2007 Sarkar S, Fox DA -
Cells of the synovium in rheumatoid arthritis. T lymphocytes.
Arthritis research & therapy 2007 Lundy SK, Sarkar S, Tesmer LA, Fox DA -
Interleukin-17 as a molecular target in immune-mediated arthritis: immunoregulatory properties of genetically modified murine dendritic cells that secrete interleukin-4.
Arthritis and rheumatism 2007 Sarkar S, Tesmer LA, Hindnavis V, Endres JL, Fox DA -
Endothelial dysfunction in rat adjuvant-induced arthritis: vascular superoxide production by NAD(P)H oxidase and uncoupled endothelial nitric oxide synthase.
Arthritis and rheumatism 2006 Haruna Y, Morita Y, Komai N, Yada T, Sakuta T, Tomita N, Fox DA, Kashihara N -
Treatment for rheumatic disorders.
The New England journal of medicine 2006 Tindall EA, Fox DA -
Immunocompetent properties of human osteoblasts: interactions with T lymphocytes.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2005 Stanley KT, VanDort C, Motyl C, Endres J, Fox DA -
Synovial biology and T cells in rheumatoid arthritis.
Pathophysiology : the official journal of the International Society for Pathophysiology 2005 Tran CN, Lundy SK, Fox DA -
Cytokine production by dendritic cells genetically engineered to express IL-4: induction of Th2 responses and differential regulation of IL-12 and IL-23 synthesis.
The journal of gene medicine 2005 Morita Y, Gupta R, Seidl KM, McDonagh KT, Fox DA -
Dendritic cells in rheumatoid arthritis.
Frontiers in bioscience : a journal and virtual library 2005 Sarkar S, Fox DA -
Expression and characterization of a novel CD6 ligand in cells derived from joint and epithelial tissues.
Journal of immunology (Baltimore, Md. : 1950) 2004 Saifullah MK, Fox DA, Sarkar S, Abidi SM, Endres J, Piktel J, Haqqi TM, Singer NG -
Xenogeneic cells and superantigen induce human T-cell activation in the absence of T-cell recognition of xenoantigen.
The Journal of laboratory and clinical medicine 2003 Diaz LA, Pai R, Endres J, Anthony P, Duzyj C, Bishu S, Morita Y, Fox DA -
Surgical management of the rheumatoid hand: consensus and controversy among rheumatologists and hand surgeons.
The Journal of rheumatology 2003 Alderman AK, Ubel PA, Kim HM, Fox DA, Chung KC -
Effectiveness of rheumatoid hand surgery: contrasting perceptions of hand surgeons and rheumatologists.
The Journal of hand surgery 2003 Alderman AK, Chung KC, Kim HM, Fox DA, Ubel PA -
CD6: expression during development, apoptosis and selection of human and mouse thymocytes.
International immunology 2002 Singer NG, Fox DA, Haqqi TM, Beretta L, Endres JS, Prohaska S, Parnes JR, Bromberg J, Sramkoski RM