Dave Graham-Squire, PhD, MA
Specialist
Family Health Care Nursing
School of Nursing
Dave Graham-Squire, PhD is a statistician working with multiple research groups in Family Health Care Nursing, the Division of Health and Society, and the Division of HIV, Infectious Diseases, and Global Medicine at San Francisco General Hospital. His research focuses on causal effects, particularly in observational studies and non-experimental settings, where randomized controlled studies are not possible.
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His methodological expertise includes statistical computation, large administrative dataset analysis, survey design, and machine learning techniques for prediction and classification. He has primarily applied these techniques to issues of public policy and medical research and has dedicated his career to improving the health of systematically marginalized populations such as persons experiencing homelessness, low-wage workers, undocumented children, and uninsured individuals and families. His work focuses on the intersection of health, income inequality, homelessness and policy, and in opportunities to draw meaningful conclusions about which policy interventions are effective at addressing these pressing issues.
His current roles include: biostatistician of an NIH-funded randomized controlled trial on community driven interventions to improve the uptake of the RSV vaccine in older Latino adults; lead analyst and data pipeline architect of a large international longitudinal study of family health outcomes; consulting statistician on public sector integrated health-social serve-housing database to understand how to best serve, and house, people experiencing homelessness.
Prior to his current position, Dr. Graham-Squire led a team of quantitative analysts as the Director of Statistics and Data Science at the UCSF Benioff Housing and Homeless Initiative (2020-2024). In that role he led the survey design of the California Statewide Survey of People Experiencing Homelessness (CASPEH), a groundbreaking representative sample of people experiencing homelessness, in the service of reducing homelessness and better serving unhoused individuals.
Before UCSF, Dr. Graham-Squire was the Lead Statistician and programmer at the UC Berkeley Center for Labor Research and Education (2006-2020), where he developed influential policy analysis tools. As sole programmer and architect, he built the initial version of the California Simulation of Insurance Markets (CalSIM), an economic microsimulation model that has generated dozens of policy briefs and become a key planning tool for Covered California. His 2014 CalSIM analysis, "A little investment goes a long way...", demonstrated how modest program changes could provide coverage to hundreds of thousands of undocumented Californians, contributing to the passage of Senate Bill 1005, the Health for All Act. He also developed a novel method combining administrative data with national survey data to estimate public program costs for specific worker groups. This methodology generated a series of reports documenting how public assistance programs effectively subsidize low-wage employers—work that proved influential in campaigns to raise the minimum wage to $15/hour across numerous states, counties, and cities, and was cited by New York Governor Andrew Cuomo when signing that state's $15 minimum wage law.
At UCSF, Dr. Graham-Squire has served on the mentorship committees of graduate student researchers, post-docs, and assistant professors, and supervised and mentored early career analysts. He received a doctorate in Statistics from the University of California at Berkeley in 2018.
Education & Training
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- Ph.D. Statistics University of California at Berkeley 08/2018
Interests
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- Causal Inference
- Biostatistics
- Systematically Marginalized Populations
- Administrative Data
- Health Insurance Coverage
- Longitudinal Analysis
- Matching Methods
- Statistical Computing
- Data Science
- Uninsured
- Homelessness
- Public Policy
- Immigration
- Pseudo Experimental Studies
Publications (13)
Top publication keywords:
Patient ReadmissionPatient IsolationSan FranciscoHospitals, PublicTrauma CentersSubstance-Related DisordersQuarantineTime-to-TreatmentMandatory ReportingWounds and InjuriesHousingFinancial SupportLength of StayHealth Insurance ExchangesEmergency Service, Hospital
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Timeliness of injury care and housing status.
Injury 2025 Decker H, Evans J, Squire DG, Colom S, Perez K, Raven M, Plevin R, Kanzaria HK, Stey A -
Housing Status and Longitudinal Care Patterns After Injury.
Annals of emergency medicine 2025 Decker H, Evans J, Squire DG, Colom S, Perez K, Raven M, Plevin R, Kanzaria HK, Stey A -
Novel methods to construct a representative sample for surveying California's unhoused population: the California Statewide Study of People Experiencing Homelessness.
American journal of epidemiology 2025 Wesson P, Graham-Squire D, Perry E, Assaf RD, Kushel M -
Association of housing status and cancer diagnosis, care coordination and outcomes in a public hospital: a retrospective cohort study.
BMJ open 2024 Decker H, Colom S, Evans JL, Graham-Squire D, Perez K, Kushel M, Wick E, Raven MC, Kanzaria HK -
Housing Status and Acute Care Use After Cancer Diagnosis.
JAMA network open 2024 Decker H, Colom S, Graham-Squire D, Wick E, Kushel MB, Raven M, Kanzaria HK
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Association of Homelessness with Before Medically Advised Discharge After Surgery.
Joint Commission journal on quality and patient safety 2024 Decker HC, Silver CM, Graham-Squire D, Pierce L, Kanzaria HK, Wick EC -
Cluster Analysis of the Highest Users of Medical, Behavioral Health, and Social Services in San Francisco.
Journal of general internal medicine 2022 Hewlett MM, Raven MC, Graham-Squire D, Evans JL, Cawley C, Kushel M, Kanzaria HK -
Analysis of Emergency Department Encounters Among High Users of Health Care and Social Service Systems Before and During the COVID-19 Pandemic.
JAMA network open 2022 Molina M, Evans J, Montoy JC, Cawley C, Graham-Squire D, Perez K, Raven M, Kanzaria HK -
Association of Shelter-in-Place Hotels With Health Services Use Among People Experiencing Homelessness During the COVID-19 Pandemic.
JAMA network open 2022 Fleming MD, Evans JL, Graham-Squire D, Cawley C, Kanzaria HK, Kushel MB, Raven MC -
Implementation of rapid and frequent SARS-CoV2 antigen testing and response in congregate homeless shelters.
PloS one 2022 Aranda-Díaz A, Imbert E, Strieff S, Graham-Squire D, Evans JL, Moore J, McFarland W, Fuchs J, Handley MA, Kushel M -
Assessment of a Hotel-Based COVID-19 Isolation and Quarantine Strategy for Persons Experiencing Homelessness.
JAMA network open 2021 Fuchs JD, Carter HC, Evans J, Graham-Squire D, Imbert E, Bloome J, Fann C, Skotnes T, Sears J, Pfeifer-Rosenblum R, Moughamian A, Eveland J, Reed A, Borne D, Lee M, Rosenthal M, Jain V, Bobba N, … -
Large repayments of premium subsidies may be owed to the IRS if family income changes are not promptly reported.
Health affairs (Project Hope) 2013 Jacobs K, Graham-Squire D, Gould E, Roby D -
Proposed regulations could limit access to affordable health coverage for workers' children and family members.
Policy brief (UCLA Center for Health Policy Research) 2011 Jacobs K, Graham-Squire D, Roby DH, Kominski GF, Kinane CM, Needleman J, Watson G, Gans D