Daniel Kerr
Junior Specialist
Medicine
School of Medicine

Education & Training

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• B.S. Chemical Biology University of California, Berkeley 05/2019

Publications (9)

Top publication keywords:
ras ProteinsNitroreductasesProtein Tyrosine Phosphatase, Non-Receptor Type 11Nucleic AcidsAntineoplastic AgentsPenicillin AmidaseReceptor Protein-Tyrosine KinasesMitogen-Activated Protein KinasesLung NeoplasmsAllosteric RegulationSulfhydryl CompoundsDrug Resistance, NeoplasmEnzyme InhibitorsFactor XSurface-Active Agents

• AXL and Error-Prone DNA Replication Confer Drug Resistance and Offer Strategies to Treat EGFR-Mutant Lung Cancer.
  Cancer discovery 2022 Noronha A, Belugali Nataraj N, Lee JS, Zhitomirsky B, Oren Y, Oster S, Lindzen M, Mukherjee S, Will R, Ghosh S, Simoni-Nieves A, Verma A, Chatterjee R, Borgoni S, Robinson W, Sinha S, Brandis A, Kerr …
• Deficiency of the splicing factor RBM10 limits EGFR inhibitor response in EGFR-mutant lung cancer.
  The Journal of clinical investigation 2022 Nanjo S, Wu W, Karachaliou N, Blakely CM, Suzuki J, Chou YT, Ali SM, Kerr DL, Olivas VR, Shue J, Rotow J, Mayekar MK, Haderk F, Chatterjee N, Urisman A, Yeo JC, Skanderup AJ, Tan AC, Tam WL, Arrieta O…
• Small-molecule targeted therapies induce dependence on DNA double-strand break repair in residual tumor cells.
  Science translational medicine 2022 Ali M, Lu M, Ang HX, Soderquist RS, Eyler CE, Hutchinson HM, Glass C, Bassil CF, Lopez OM, Kerr DL, Falcon CJ, Yu HA, Hata AN, Blakely CM, McCoach CE, Bivona TG, Wood KC
• A self-immolative linker that releases thiols detects penicillin amidase and nitroreductase with high sensitivity via absorption spectroscopy.
  Chemical communications (Cambridge, England) 2022 Espinoza EM, Røise JJ, He M, Li IC, Agatep AK, Udenyi P, Han H, Jackson N, Kerr DL, Chen D, Stentzel MR, Ruan E, Riley L, Murthy N
• Acid-Sensitive Surfactants Enhance the Delivery of Nucleic Acids.
  Molecular pharmaceutics 2021 Røise JJ, Han H, Li J, Kerr DL, Taing C, Behrouzi K, He M, Ruan E, Chan LY, Espinoza EM, Reinhard S, Thakker K, Kwon J, Mofrad MRK, Murthy N

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• Allosteric SHP2 inhibitors in cancer: Targeting the intersection of RAS, resistance, and the immune microenvironment.
  Current opinion in chemical biology 2021 Kerr DL, Haderk F, Bivona TG
• Therapy-Induced Evolution of Human Lung Cancer Revealed by Single-Cell RNA Sequencing.
  Cell 2020 Maynard A, McCoach CE, Rotow JK, Harris L, Haderk F, Kerr DL, Yu EA, Schenk EL, Tan W, Zee A, Tan M, Gui P, Lea T, Wu W, Urisman A, Jones K, Sit R, Kolli PK, Seeley E, Gesthalter Y, Le DD, Yamauchi KA…
• A novel fluorescent surfactant enhances the delivery of the Cas9 ribonucleoprotein and enables the identification of edited cells.
  Chemical communications (Cambridge, England) 2019 Li J, Røise JJ, Zhang J, Yang J, Kerr DL, Han H, Murthy N
• Nitro Sulfonyl Fluorides are a new pharmacophore for the development of antibiotics.
  Molecular systems design & engineering 2018 Sadlowski C, Park B, Araújo C, Das S, Kerr DL, He M, Han H, Riley L, Murthy N