Daniel Vigneron, PhD
Professor
Radiology
School of Medicine

415-476-3343

Daniel B. Vigneron, PhD, is a Professor in the Departments of Radiology & Biomedical Imaging, Bioengineering & Therapeutic Sciences and Neurological Surgery at the University of California, San Francisco.

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He is also Director of the Advanced Imaging Technologies Specialized Resource Group, the UCSF Research Resource Programs’s (RRP) Human Imaging Core Services recharge and,the P41 NIH/NBIBI Hyperpolarized MRI Technology Resource Center. He is also the Operations Director of the Surbeck Laboratory for Advanced Imaging, Chair of the Radiology Research Safety & Compliance Committee, and a core member of the UCB/UCSF Graduate Group in Bioengineering at UCSF. Dr. Vigneron’s professional activities aims on the advancement of biomedical MRI research.

Dr. Vigneron’s research focuses on the development of advanced functional and metabolic Magnetic Resonance Imaging (MRI) techniques for both basic research and clinical assessments of human diseases. This requires the development of new hardware/software and MR protocols to provide biochemical information in addition to the anatomic information provided by clinical MRI. This research has been reported in over 330 publications resulting in over 33,000 citations and has been funded by 20+ NIH grant awards as PI and 6 NIH awards as the primary Mentor.

Dr. Vigneron’s research was initially focused on developing 3D MR spectroscopic imaging for the non-invasive assessment of brain tumor metabolism. Another major research interest of Dr. Vigneron’s is the characterization of prostate cancer using novel MR metabolic imaging techniques. Developing specialized acquisitions techniques for prostate cancer MRSI has been a major project for Dr. Vigneron and his group. These techniques have now been used in over 8000 research and clinical studies at UCSF. He also has led technical development aspects for the UCSF Hyperpolarized (HP) Carbon-13 MR molecular imaging program and is the PI for 6 projects including NIH P41 center grant, 2 RO1's, a P01, and a Bioengineering Research Partnership (BRP U01) focused on this new stable isotope molecular MR imaging approach. This exciting new technology detects not only the uptake of the HP molecule but also its metabolism in vivo.

Dr. Vigneron obtained his BA in Chemistry from Wesleyan University in Middletown, Connecticut in 1983, and he received his PhD in Pharmaceutical Chemistry from UCSF in 1988 for his graduate work on applying new MRI techniques for characterizing disease and therapy response. In 1990, he completed a postdoctoral fellowship from the Fox Chase Cancer Center in Philadelphia and in 1991 he completed a postdoctoral fellowship from UCSF.

Expertise: Radiology and Biomedical Imaging

Specialty: MRI, hyperpolarized MRI techniques, brain tumor, prostate cancer

Professional Interests: Magnetic Resonance Imaging, Magnetic Resonance Spectroscopy, Molecular Imaging, Metabolic Imaging, Diffusion tensor imaging, Oncologic Imaging, Prostate Cancer Imaging, Pediatric Imaging, Radiology.

Education and Training:

  • Bachelor of Arts: Wesleyan University, Middletown, Connecticut - Chemistry, Pre-Med Studies
  • Doctor of Philosophy: University of California, San Francisco - Pharmaceutical Chemistry
  • Research Fellow: Fox Chase Cancer Center, Philadelphia
  • Visiting Postdoctoral Scholar: University of California, San Francisco - Department of Radiology

Awards

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  • Gold Medal Award, World Molecular Imaging Society, 2014
  • Distinguished Investigator Award, Academy of Radiology Research, 2013
  • Distinguished Service Award as Reviewer for Journal of Magnetic Resonance Imaging, International Society of Magnetic Resonance in Medicine, 2011
  • Awarded Fellow of ISMRM, International Society of Magnetic Resonance in Medicine, 2009
  • Elected to the College of Fellow, American Institute for Medical and Biological Engineering, 2007
  • Outstanding Presentation Award, American Society of Neuroradiology, 2007
  • Outstanding Presentation Award in Pediatric Neuroradiology - The Derek Harwood-Nash Award, American Society of Neuroradiology, 2001
  • Prostate Cancer Research Award, CaP Cure Foundation, 2000
  • Prostate Cancer Research Award, CaP Cure Foundation, 1999
  • Prostate Cancer Research Award, CaP Cure Foundation, 1998
  • National Research Service Award, National Cancer Institute, National Institutes of Health, 1990
  • Hawk Prize for Most Effective Work in Biochemistry, Wesleyan University, 1983

Education & Training

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  • Ph.D. Visiting Postdoctoral Scholar Dept. of Radiology UC, San Francisco 1991
  • Research Fellow Fox Chase Cancer Center 1990
  • Ph.D. Graduate Division (Pharmaceutical Chemistry) University of California, San Francisco 1988
  • B.A. Chemistry, Pre-Med Studies Wesleyan University 1983

Interests

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  • Molecular Imaging
  • Magnetic Resonance Spectroscopy
  • Oncologic Imaging
  • Metabolic Imaging
  • Radiology
  • Diffusion tensor imaging
  • Prostate Cancer Imaging
  • Magnetic Resonance Imaging
  • Pediatric Imaging

Websites

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Videos

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Grants and Projects

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Publications (359)

Top publication keywords:
Molecular ImagingCarbon IsotopesMagnetic Resonance SpectroscopyImage Processing, Computer-AssistedPhantoms, ImagingMagnetic Resonance ImagingImage EnhancementCarbon-13 Magnetic Resonance SpectroscopyPyruvic AcidLactic AcidEcho-Planar ImagingImaging, Three-DimensionalProstatic NeoplasmsUreaAlanine

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