Daniel Ramos, DDS, PhD
Professor Emeritus
Orofacial Sciences
School of Dentistry

Education & Training

Show all (2) Hide

• Ph.D. Dentistry (Oral Biology) University of California, San Francisco 1994
• D.D.S. Dentistry University of California, San Francisco 1988

Websites

Show all (1) Hide

• Profile at UCSF Cancer Center (cancer.ucsf.edu)

Grants and Projects

Show all (6) Hide

• Regulatory function of fyn in oral SCC invasion, NIH, 1997-2009
• Oral Melanoma: Alpha v Beta 3 Expression and Metastasis, NIH, 2000-2007
• Matrix Remodeling in Oral Squamous Cell Carcinoma, NIH, 1999-2004
• Molecular Mechanisms of Invasion in Oral Cancer, NIH, 1900-2004
• Regulated Expression of Tenascin and Avb6 in Oral Cancer, NIH, 1997-2003
• Lymphatic Metastasis of Melanoma Tumor Cells, NIH, 1988-1994

Publications (38)

Top publication keywords:
Epithelial-Mesenchymal TransitionIntegrinsBasiginIntegrin alphaVbeta3Antigens, NeoplasmStem Cell ResearchIntegrin beta ChainsTenascinCarcinoma, Squamous CellMouth NeoplasmsFocal Epithelial HyperplasiaTongue NeoplasmsSpheroids, CellularHereditary Sensory and Autonomic NeuropathiesProto-Oncogene Proteins c-fyn

• Mis-spliced transcripts generate de novo proteins in TDP-43-related ALS/FTD.
  Science translational medicine 2024 Seddighi S, Qi YA, Brown AL, Wilkins OG, Bereda C, Belair C, Zhang YJ, Prudencio M, Keuss MJ, Khandeshi A, Pickles S, Kargbo-Hill SE, Hawrot J, Ramos DM, Yuan H, Roberts J, Sacramento EK, Shah SI, …
• An ANXA11 P93S variant dysregulates TDP-43 and causes corticobasal syndrome.
  Research square 2023 Snyder A, Ryan VH, Hawrot J, Lawton S, Ramos DM, Qi YA, Johnson K, Reed X, Johnson NL, Kollasch AW, Duffy M, VandeVrede L, Cochran JN, Miller BL, Toro C, Bielekova B, Yokoyama JS, Marks DS, Kwan JY, …
• Application of Aligned-UMAP to longitudinal biomedical studies.
  Patterns (New York, N.Y.) 2023 Dadu A, Satone VK, Kaur R, Koretsky MJ, Iwaki H, Qi YA, Ramos DM, Avants B, Hesterman J, Gunn R, Cookson MR, Ward ME, Singleton AB, Campbell RH, Nalls MA, Faghri F
• Mis-spliced transcripts generate de novo proteins in TDP-43-related ALS/FTD.
  bioRxiv : the preprint server for biology 2023 Seddighi S, Qi YA, Brown AL, Wilkins OG, Bereda C, Belair C, Zhang Y, Prudencio M, Keuss MJ, Khandeshi A, Pickles S, Hill SE, Hawrot J, Ramos DM, Yuan H, Roberts J, Kelmer Sacramento E, Shah SI, Nalls…
• Maximizing CRISPRi efficacy and accessibility with dual-sgRNA libraries and optimal effectors.
  eLife 2022 Replogle JM, Bonnar JL, Pogson AN, Liem CR, Maier NK, Ding Y, Russell BJ, Wang X, Leng K, Guna A, Norman TM, Pak RA, Ramos DM, Ward ME, Gilbert LA, Kampmann M, Weissman JS, Jost M

Show all (33 more) Hide

• A reference human induced pluripotent stem cell line for large-scale collaborative studies.
  Cell stem cell 2022 Pantazis CB, Yang A, Lara E, McDonough JA, Blauwendraat C, Peng L, Oguro H, Kanaujiya J, Zou J, Sebesta D, Pratt G, Cross E, Blockwick J, Buxton P, Kinner-Bibeau L, Medura C, Tompkins C, Hughes S, …
• Tackling neurodegenerative diseases with genomic engineering: A new stem cell initiative from the NIH.
  Neuron 2021 Ramos DM, Skarnes WC, Singleton AB, Cookson MR, Ward ME
• Patient and providers' satisfaction with tele(oral)medicine during the COVID-19 pandemic.
  Oral diseases 2020 Villa A, Sankar V, Shazib MA, Ramos D, Veluppillai P, Wu A, Shiboski C
• Focal Epithelial Hyperplasia in a Child with Hereditary Sensory and Autonomic Neuropathy type IV: A Rare Co-Occurrence.
  Journal of dentistry for children (Chicago, Ill.) 2019 Calvo JM, Stewart R, Ramos D
• αvβ6-Fyn Kinase Promotes Epithelial Phenotype in SYF Cells.
  Anticancer research 2018 Lee C, Ramos DM
• Multicellular Spheroids as a Model for Hypoxia-induced EMT.
  Anticancer research 2016 Lee C, Siu A, Ramos DM
• Regulation of Multicellular Spheroids by MAPK and FYN Kinase.
  Anticancer research 2016 Lee C, Ramos DM
• Differential diagnosis and management of oral ulcers.
  Seminars in cutaneous medicine and surgery 2015 Siu A, Landon K, Ramos DM
• Gingival pustules and sterile diffuse sclerosing osteomyelitis as a feature of synovitis, acne, pustulosis, hyperostosis, osteitis (SAPHO) syndrome.
  Oral surgery, oral medicine, oral pathology and oral radiology 2015 Chou A, Schulman JM, Gross AJ, Jordan RC, Ramos DM
• Differential spheroid formation by oral cancer cells.
  Anticancer research 2014 Lee C, Lee C, Atakilit A, Siu A, Ramos DM
• Wnt signaling regulates pulp volume and dentin thickness.
  Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2014 Lim WH, Liu B, Cheng D, Hunter DJ, Zhong Z, Ramos DM, Williams BO, Sharpe PT, Bardet C, Mah SJ, Helms JA
• The cytoplasmic extension of the integrin β6 subunit regulates epithelial-to-mesenchymal transition.
  Anticancer research 2014 Lee C, Lee C, Lee S, Siu A, Ramos DM
• Expression of EMMPRIN modulates mediators of tumor invasion in oral squamous cell carcinoma.
  Journal of the California Dental Association 2013 Siu A, Chang J, Lee C, Lee S, Lee C, Ramos DM
• Alphavbeta3 suppresses the RhoA-LIMK1 pathway in K1735 melanoma.
  Journal of the California Dental Association 2012 Lee C, Siu A, Chang J, Dang D, Ramos DM
• Revisiting epithelial-to-mesenchymal transition through adenoid cystic carcinoma.
  Anticancer research 2012 Siu A, Lee C, Pham E, Ramos DM
• Stem cell markers as predictors of oral cancer invasion.
  Anticancer research 2012 Siu A, Lee C, Dang D, Lee C, Ramos DM
• EMMPRIN expression in oral SCC is regulated by FYN kinase.
  Anticancer research 2011 Ramos DM, Dang D
• Expression of Fyn kinase modulates EMT in oral cancer cells.
  Anticancer research 2010 Lewin B, Siu A, Baker C, Dang D, Schnitt R, Eisapooran P, Ramos DM
• Modulation of EGFR by oral squamous cell carcinoma cell lines.
  Journal of the California Dental Association 2009 Dang D, Sadler S, Ramos DM
• Identification of {alpha}v{beta}6-positive stem cells in oral squamous cell carcinoma.
  Anticancer research 2009 Dang D, Ramos DM
• The role of the integrin alpha v beta6 in regulating the epithelial to mesenchymal transition in oral cancer.
  Anticancer research 2009 Ramos DM, Dang D, Sadler S
• EMMPRIN modulates migration and deposition of TN-C in oral squamous carcinoma.
  Anticancer research 2008 Dang D, Atakilit A, Ramos DM
• Alphavbeta3 integrin and cofilin modulate K1735 melanoma cell invasion.
  Experimental cell research 2005 Dang D, Bamburg JR, Ramos DM
• The expression of integrin alpha(v)beta6 promotes the epithelial cell morphology and suppresses invasive behavior in transformed oral keratinocytes.
  Anticancer research 2005 Mogi S, Dang D, Van Waes C, Ellis D, Atakilit A, Ramos DM
• Beta-6 Integrin, tenascin-C, and MMP-1 expression in salivary gland neoplasms.
  Oral oncology 2005 Westernoff TH, Jordan RC, Regezi JA, Ramos DM, Schmidt BL
• Tenascin-C deposition requires beta3 integrin and Src.
  Biochemical and biophysical research communications 2004 Yang Y, Dang D, Mogi S, Ramos DM
• Matrix metalloproteinases and TGFbeta1 modulate oral tumor cell matrix.
  Biochemical and biophysical research communications 2004 Dang D, Yang Y, Li X, Atakilit A, Regezi J, Eisele D, Ellis D, Ramos DM
• Specific alpha v integrin receptors modulate K1735 murine melanoma cell behavior.
  Biochemical and biophysical research communications 2003 Yang Y, Dang D, Atakilit A, Schmidt B, Regezi J, Li X, Eisele D, Ellis D, Ramos DM
• Alphavbeta6-Fyn signaling promotes oral cancer progression.
  The Journal of biological chemistry 2003 Li X, Yang Y, Hu Y, Dang D, Regezi J, Schmidt BL, Atakilit A, Chen B, Ellis D, Ramos DM
• Proliferation and invasion factors in HIV-associated dysplastic and nondysplastic oral warts and in oral squamous cell carcinoma: an immunohistochemical and RT-PCR evaluation.
  Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics 2002 Regezi JA, Dekker NP, Ramos DM, Li X, Macabeo-Ong M, Jordan RC
• Oral mucosal carcinogenesis in SENCAR mice.
  Anticancer research 2002 Kim TW, Chen Q, Shen X, Regezi JA, Ramos DM, Tanaka H, Jordan RC, Kramer RH
• Tenascin and beta 6 integrin are overexpressed in floor of mouth in situ carcinomas and invasive squamous cell carcinomas.
  Oral oncology 2002 Regezi JA, Ramos DM, Pytela R, Dekker NP, Jordan RC
• Expression of integrin beta 6 enhances invasive behavior in oral squamous cell carcinoma.
  Matrix biology : journal of the International Society for Matrix Biology 2002 Ramos DM, But M, Regezi J, Schmidt BL, Atakilit A, Dang D, Ellis D, Jordan R, Li X