Daniel Fried, PhD
Professor
Preventive & Restor Dent Sci
School of Dentistry

Grants and Projects

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• Imaging Dental Caries with SWIR Light, NIH, 2019-2024
• Optical Methods for Lesion Activity Assessment, NIH, 2018-2023
• Selective Ablation of Dental Caries and Composites, NIH, 2009-2019
• Early Caries Detection with Near-IR Light, NIH, 2002-2018
• Clinical Assessment of Tooth Demineralization & Remineralization with PS-OCT, NIH, 2006-2016
• Laser Ablation of Dental Hard Tissues, NIH, 2002-2008
• Ir Laser Ablation of Dental Hard Tissue, NIH, 1997-2003
• Multipurpose Co2 Tea Laser for Dental Applications, NIH, 2000-2001

Publications (196)

Top publication keywords:
Dental CariesDental EnamelMicroscopy, PolarizationTransilluminationFluoridesComposite ResinsLaser TherapyToothSpectroscopy, Near-InfraredRoot CariesTomography, Optical CoherenceDentinLasers, GasInfrared RaysTooth Demineralization

• Short-Wavelength Infrared Imaging of Infected and Affected Dentin.
  Diagnostics (Basel, Switzerland) 2024 Ng M, Ho YC, Wycoff S, Zhu Y, Fried D
• Special Section Guest Editorial: Short Wave Infrared Techniques and Applications in Biomedical Optics.
  Journal of biomedical optics 2023 Fried D, Pierce M, Roblyer D
• Longitudinal assessment of dental erosion-abrasion by cross-polarization optical coherence tomography in vitro.
  Brazilian oral research 2023 Romero MJR, Bezerra SJC, Fried D, Lippert F, Eckert GJ, Hara AT
• Diagnostic Performance of Multispectral SWIR Transillumination and Reflectance Imaging for Caries Detection.
  Diagnostics (Basel, Switzerland) 2023 Zhu Y, Ng C, Le O, Ho YC, Fried D
• Exploratory Analysis of Objective Outcome Measures for the Clinical Assessment of Erosive Tooth Wear.
  Diagnostics (Basel, Switzerland) 2023 Romero MJRH, Ungar PS, Fried D, Lippert F, Zero DT, Zunt S, Eckert GJ, Gossweiler AG, Elkington-Stauss DJ, Tamayo-Cabeza G, Kelly AB, Bartels T, Kita C, Wewers E, Hara AT

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• Time-resolved SWIR imaging for the assessment of the activity of occlusal caries lesions.
  Journal of biophotonics 2023 Ng M, Wycoff S, Zhu Y, Ho YC, Takasuka H, Fried D
• Monitoring lesion activity on primary teeth with CP-OCT and SWIR reflectance imaging.
  Lasers in surgery and medicine 2023 Zhu Y, Kim J, Lin B, Fried D
• Active Surveillance of Root Caries in Vivo with CP-OCT.
  Diagnostics (Basel, Switzerland) 2023 Zhu Y, Kim M, Curtis D, Wang J, Le O, Fried D
• Assessment of the activity of secondary caries lesions with short-wavelength infrared, thermal, and optical coherence tomographic imaging.
  Journal of biomedical optics 2023 Chang NN, Dillas T, Zhu Y, Fried D
• Assessing lesion activity of secondary lesions on extracted teeth by thermal dehydration measurement and optical coherence tomography.
  Proceedings of SPIE--the International Society for Optical Engineering 2022 Chang NN, Dillas T, Fried D
• Caries inhibition of simulated active caries lesions with CO2 laser irradiation and fluoride.
  Proceedings of SPIE--the International Society for Optical Engineering 2022 Tressel J, Kashirtsev F, Cheung K, Simon J, Fried D
• Dehydration imaging of dental fluorosis at 1950 nm.
  Proceedings of SPIE--the International Society for Optical Engineering 2022 Kashirtsev F, Tressel J, Fried D
• Evaluating interproximal and occlusal lesion severity with a dual SWIR transillumination/reflectance probe.
  Proceedings of SPIE--the International Society for Optical Engineering 2022 Zhu Y, Fried D
• Use of SWIR dehydration and OCT to assess the complete arrest of simulated incipient caries lesions.
  Proceedings of SPIE--the International Society for Optical Engineering 2022 Chang NY, Tressel J, Kashirtsev F, Fried D
• Measurement of the Depth of Lesions on Proximal Surfaces with SWIR Multispectral Transillumination and Reflectance Imaging.
  Diagnostics (Basel, Switzerland) 2022 Zhu Y, Fried D
• Monitoring silver diamine fluoride application with optical coherence tomography and thermal imaging: An in vitro proof of concept study.
  Lasers in surgery and medicine 2022 Abdelaziz M, Yang V, Chang NN, Darling C, Fried W, Seto J, Fried D
• High contrast imaging of dental fluorosis in the short wavelength infrared.
  Journal of biophotonics 2021 Kashirtsev F, Tressel J, Simon JC, Fried D
• Cross-polarization optical coherence tomographic assessment of in situ simulated erosive tooth wear.
  Journal of biophotonics 2021 Romero MJRH, Bezerra SJC, Fried D, Yang V, Lippert F, Eckert GJ, Zero DT, Hara AT
• Computer-Controlled CO2 Laser Ablation System for Cone-beam Computed Tomography and Digital Image Guided Endodontic Access: A Pilot Study.
  Journal of endodontics 2021 Simon JC, Kwok JW, Vinculado F, Fried D
• Dynamic SWIR imaging near the 1950-nm water absorption band for caries lesion diagnosis.
  Journal of biomedical optics 2021 Tressel JT, Abdelaziz M, Fried D
• Compact in vivo handheld dual SWIR transillumination/reflectance imaging system for the detection of proximal and occlusal lesions.
  Proceedings of SPIE--the International Society for Optical Engineering 2021 Zhu Y, Simon J, Ng C, Fried D
• High contrast reflectance imaging at 1950 nm for the assessment of lesion activity on extracted teeth.
  Proceedings of SPIE--the International Society for Optical Engineering 2021 Tressel J, Abdelaziz M, Fried D
• Imaging dental fluorosis at SWIR wavelengths from 1300 to 2000-nm.
  Proceedings of SPIE--the International Society for Optical Engineering 2021 Kashirtsev F, Simon JC, Fried D
• Infrared imaging confirms the role of the transparent surface zone in arresting dental caries.
  Proceedings of SPIE--the International Society for Optical Engineering 2021 Liu H, Chang NY, Gao W, Fried D
• Multispectral SWIR images of the pulp-chamber of posterior teeth in vitro.
  Proceedings of SPIE--the International Society for Optical Engineering 2021 Simon JC, Mogire EO, Yun SY, Fried D
• High Contrast Reflectance Imaging of Enamel Demineralization and Remineralization at 1950-nm for the Assessment of Lesion Activity.
  Lasers in surgery and medicine 2021 Fried WA, Abdelaziz M, Darling CL, Fried D
• Dual short wavelength infrared transillumination/reflectance mode imaging for caries detection.
  Journal of biomedical optics 2021 Zhu Y, Abdelaziz M, Simon J, Le O, Fried D
• Thermal Imaging of Root Caries In Vivo.
  Journal of dental research 2020 Yang V, Zhu Y, Curtis D, Le O, Chang NYN, Fried WA, Simon JC, Banan P, Darling CL, Fried D
• A SWIR imaging handpiece for the clinical assessment of lesion activity via dehydration. Preclinical Assessment.
  Proceedings of SPIE--the International Society for Optical Engineering 2020 Fried WA, Zhu Y, Yang V, Chang NY, Fried D
• A dual handheld SWIR transillumination/reflectance probe for imaging lesions on tooth occlusal and proximal surfaces.
  Proceedings of SPIE--the International Society for Optical Engineering 2020 Zhu Y, Chang NY, Fried WA, Yang V, Fried D
• A thermal imaging handpiece for the clinical assessment of lesion activity on root surfaces via dehydration.
  Proceedings of SPIE--the International Society for Optical Engineering 2020 Yang VB, Chang NY, Fried D
• In vivo spectral guided removal of composite from tooth surfaces with a CO2 laser.
  Proceedings of SPIE--the International Society for Optical Engineering 2020 Simon JC, Choi JH, Jang A, Fried D
• Optical Coherence Tomography (OCT) for the evaluation of internal adaptation of class V resin restorations on Dentin.
  Proceedings of SPIE--the International Society for Optical Engineering 2020 Abdelaziz M, Zuluaga AF, Betancourt F, Fried D, Krejci I, Bortolotto T
• SWIR, Thermal and CP-OCT imaging probes for the in vivo assessment of the activity of root caries lesions.
  Proceedings of SPIE--the International Society for Optical Engineering 2020 Chang NY, Zhu Y, Curtis D, Le O, Yang V, Fried WA, Simon JC, Banan P, Darling CL, Fried D
• Enhancing the detection of proximal cavities on near infrared transillumination images with Indocyanine Green (ICG) as a contrast medium: In vitro proof of concept studies.
  Journal of dentistry 2019 Abdelaziz M, Krejci I, Fried D
• Measurement of the shrinkage of natural and simulated lesions on root surfaces using CP-OCT.
  Journal of dentistry 2019 Yang V, Fried D
• In vitro longitudinal evaluation of enamel wear by cross-polarization optical coherence tomography.
  Dental materials : official publication of the Academy of Dental Materials 2019 Alghilan MA, Lippert F, Platt JA, Eckert GJ, González-Cabezas C, Fried D, Hara AT
• Image-Guided Ablation of Dental Calculus From Root Surfaces Using a DPSS Er:YAG Laser.
  Lasers in surgery and medicine 2019 Fried WA, Chan KH, Darling CL, Curtis DA, Fried D
• Near-infrared imaging of demineralization on the occlusal surfaces of teeth without the interference of stains.
  Journal of biomedical optics 2019 Ng C, Almaz E, Simon J, Fried D, Darling C
• An appliance for monitoring the shrinkage of root caries with OCT.
  Proceedings of SPIE--the International Society for Optical Engineering 2019 Yang VB, Fried D
• Image guided laser ablation of demineralization from root surfaces.
  Proceedings of SPIE--the International Society for Optical Engineering 2019 Dhillon N, Chan KH, Yang VB, Fried D
• Selective removal of dental calculus with a diode-pumped Er:YAG laser.
  Proceedings of SPIE--the International Society for Optical Engineering 2019 Fried WA, Chan KH, Darling CL, Fried D
• The Relationship of Dehydration Rate and Transparent Surface Layer Thickness for Coronal Lesions on Extracted Teeth.
  Proceedings of SPIE--the International Society for Optical Engineering 2019 Chang NN, Abdelaziz M, Fried D
• The contrast of demineralization on tooth occlusal surfaces from 405 to 1950-nm with varying depth.
  Proceedings of SPIE--the International Society for Optical Engineering 2019 Mohajerani N, Chan KH, Yang VB, Fried D, Darling CL
• Impact of surface micromorphology and demineralization severity on enamel loss measurements by cross-polarization optical coherence tomography.
  Journal of dentistry 2018 Alghilan MA, Lippert F, Platt JA, Eckert GJ, González-Cabezas C, Fried D, Hara AT
• Use of a DPSS Er:YAG laser for the selective removal of composite from tooth surfaces.
  Biomedical optics express 2018 Fried WA, Chan KH, Darling CL, Fried D
• Selective ablation of dental caries using coaxial Co2 (9.3-μm) and near-IR (1880-nm) lasers.
  Lasers in surgery and medicine 2018 Chan KH, Fried D
• Cross-polarization reflectance imaging of root caries and dental calculus on extracted teeth at wavelengths from 400 to 2350 nm.
  Journal of biophotonics 2018 Yang VB, Curtis DA, Fried D
• Fluorescence and Near-Infrared Light Transillumination.
  Dental clinics of North America 2018 Amaechi BT, Owosho AA, Fried D
• Optical Coherence Tomography.
  Dental clinics of North America 2018 Katkar RA, Tadinada SA, Amaechi BT, Fried D
• Multispectral cross-polarization reflectance measurements suggest high contrast of demineralization on tooth surfaces at wavelengths beyond 1300 nm due to reduced light scattering in sound enamel.
  Journal of biomedical optics 2018 Chan KH, Fried D
• Image-guided Removal of Interproximal Lesions with a CO2 Laser.
  Proceedings of SPIE--the International Society for Optical Engineering 2018 Ngo A, Chan KH, Le O, Simon JC, Fried D
• Multispectral near-infrared reflectance and transillumination imaging of occlusal carious lesions: Variation in lesion contrast with lesion depth.
  Proceedings of SPIE--the International Society for Optical Engineering 2018 Simon JC, Curtis DA, Darling CL, Fried D
• SWIR reflectance imaging of demineralization on the occlusal surfaces of teeth beyond 1700 nm.
  Proceedings of SPIE--the International Society for Optical Engineering 2018 Ng C, Simon JC, Fried D, Darling CL
• Lesion Dehydration Rate Changes with the Surface Layer Thickness during Enamel Remineralization.
  Proceedings of SPIE--the International Society for Optical Engineering 2018 Chang NN, Jew JM, Fried D
• Selective Ablation of Carious Lesions using an Integrated Near-IR Imaging System and a Novel 9.3-µm CO2 Laser.
  Proceedings of SPIE--the International Society for Optical Engineering 2018 Chan KH, Fried NM, Fried D
• Influence of multi-wavelength laser irradiation of enamel and dentin surfaces at 0.355, 2.94, and 9.4 μm on surface morphology, permeability, and acid resistance.
  Lasers in surgery and medicine 2017 Chang NN, Jew JM, Simon JC, Chen KH, Lee RC, Fried WA, Cho J, Darling CL, Fried D
• Automated ablation of dental composite using an IR pulsed laser coupled to a plume emission spectral feedback system.
  Lasers in surgery and medicine 2017 Jang AT, Chan KH, Fried D
• Near-IR and CP-OCT imaging of suspected occlusal caries lesions.
  Lasers in surgery and medicine 2017 Simon JC, Kang H, Staninec M, Jang AT, Chan KH, Darling CL, Lee RC, Fried D
• Influence of a pulsed CO2 laser operating at 9.4  μm on the surface morphology, reflectivity, and acid resistance of dental enamel below the threshold for melting.
  Journal of biomedical optics 2017 Kim JW, Lee R, Chan KH, Jew JM, Fried D
• Assessment of cavitation in artificial approximal dental lesions with near-IR imaging.
  Proceedings of SPIE--the International Society for Optical Engineering 2017 Simon JC, Darling CL, Fried D
• Assessment of radicular dentin permeability after irradiation with CO2 laser and endodontic irrigation treatments with thermal imaging.
  Proceedings of SPIE--the International Society for Optical Engineering 2017 Cho H, Lee RC, Chan KH, Fried D
• Automated ablation of dental composite using an IR pulsed laser coupled to a plume emission spectral feedback system.
  Proceedings of SPIE--the International Society for Optical Engineering 2017 Jang AT, Chan KH, Fried D
• High-Contrast Reflectance Imaging of Composite Restorations Color-Matched to Tooth Structure at 1000-2300-nm.
  Proceedings of SPIE--the International Society for Optical Engineering 2017 Fried WA, Simon JC, Darling CL, Le O, Fried D
• Influence of Multi-Wavelength Laser Irradiation of Enamel and Dentin Surfaces on Surface Morphology and Permeability.
  Proceedings of SPIE--the International Society for Optical Engineering 2017 Chang NN, Jew J, Simon JC, Chan KH, Lee RC, Fried WA, Cho J, Darling CL, Fried D
• Near-infrared imaging of enamel hypomineralization due to developmental defects.
  Proceedings of SPIE--the International Society for Optical Engineering 2017 Lee RC, Jang A, Fried D
• Optical changes of dentin in the near-IR as a function of mineral content.
  Proceedings of SPIE--the International Society for Optical Engineering 2017 Berg RA, Simon JC, Fried D, Darling CL
• Selective Laser Ablation of Carious Lesions using Simultaneous Scanned Near-IR Diode and CO2 Lasers.
  Proceedings of SPIE--the International Society for Optical Engineering 2017 Chan KH, Fried D
• Selective removal of natural caries lesions from dentin and tooth occlusal surfaces using a diode-pumped Er:YAG laser.
  Proceedings of SPIE--the International Society for Optical Engineering 2017 Jew J, Chan KH, Darling CL, Fried D
• Synergistic effect of fluoride and laser irradiation for the inhibition of the demineralization of dental enamel.
  Proceedings of SPIE--the International Society for Optical Engineering 2017 Lee R, Chan KH, Jew J, Simon JC, Fried D
• Use of an optical clearing agent to enhance the visibility of subsurface structures and lesions from tooth occlusal surfaces.
  Journal of biomedical optics 2016 Kang H, Darling CL, Fried D
• Enamel Thickness Determination by Optical Coherence Tomography: In vitro Validation.
  Caries research 2016 Algarni A, Kang H, Fried D, Eckert GJ, Hara AT
• Near-IR transillumination and reflectance imaging at 1,300 nm and 1,500-1,700 nm for in vivo caries detection.
  Lasers in surgery and medicine 2016 Simon JC, Lucas SA, Staninec M, Tom H, Chan KH, Darling CL, Cozin MJ, Lee RC, Fried D
• Activity assessment of root caries lesions with thermal and near-IR imaging methods.
  Journal of biophotonics 2016 Lee RC, Darling CL, Staninec M, Ragadio A, Fried D
• Infrared Methods for Assessment of the Activity of Natural Enamel Caries Lesions.
  IEEE journal of selected topics in quantum electronics : a publication of the IEEE Lasers and Electro-optics Society 2016 Lee RC, Staninec M, Le O, Fried D
• Clinical monitoring of smooth surface enamel lesions using CP-OCT during nonsurgical intervention.
  Lasers in surgery and medicine 2016 Chan KH, Tom H, Lee RC, Kang H, Simon JC, Staninec M, Darling CL, Pelzner RB, Fried D
• A new sealed RF-excited CO2 laser for enamel ablation operating at 9.4-μm with a pulse duration of 26-μs.
  Proceedings of SPIE--the International Society for Optical Engineering 2016 Chan KH, Jew JM, Fried D
• A system for simultaneous near-infrared reflectance and transillumination imaging of occlusal carious lesions.
  Proceedings of SPIE--the International Society for Optical Engineering 2016 Simon JC, Darling CL, Fried D
• Assessment of remineralized dentin lesions with thermal and near-infrared reflectance imaging.
  Proceedings of SPIE--the International Society for Optical Engineering 2016 Lee RC, Darling CL, Fried D
• Assessment of simulated lesions on primary teeth with near-infrared imaging.
  Proceedings of SPIE--the International Society for Optical Engineering 2016 Tam W, Lee RC, Lin B, Simon JC, Fried D
• Enhancement of OCT images with vinyl polysiloxane (VPS).
  Proceedings of SPIE--the International Society for Optical Engineering 2016 Kang H, Darling CL, Fried D
• Evaluation of enamel surface modification using PS-OCT after laser treatment to increase resistance to demineralization.
  Proceedings of SPIE--the International Society for Optical Engineering 2016 Kim JW, Chan KH, Fried D
• Influence of stains on lesion contrast in the pits and fissures of tooth occlusal surfaces from 800-1600-nm.
  Proceedings of SPIE--the International Society for Optical Engineering 2016 Almaz EC, Simon JC, Fried D, Darling CL
• Selective removal of dental composite with a diode-pumped Er:YAG laser.
  Proceedings of SPIE--the International Society for Optical Engineering 2016 Fried WA, Chan KH, Darling CL, Fried D
• Selective removal of esthetic composite restorations with spectral guided laser ablation.
  Proceedings of SPIE--the International Society for Optical Engineering 2016 Yi I, Chan KH, Tsuji GH, Staninec M, Darling CL, Fried D
• Near-infrared imaging of secondary caries lesions around composite restorations at wavelengths from 1300-1700-nm.
  Dental materials : official publication of the Academy of Dental Materials 2016 Simon JC, A Lucas S, Lee RC, Darling CL, Staninec M, Vaderhobli R, Pelzner R, Fried D
• Near-IR image-guided laser ablation of demineralization on tooth occlusal surfaces.
  Lasers in surgery and medicine 2016 Tom H, Chan KH, Darling CL, Fried D
• Assessment of remineralization via measurement of dehydration rates with thermal and near-IR reflectance imaging.
  Journal of dentistry 2015 Lee RC, Darling CL, Fried D
• Assessment of remineralization in simulated enamel lesions via dehydration with near-IR reflectance imaging.
  Proceedings of SPIE--the International Society for Optical Engineering 2015 Lee RC, Darling CL, Fried D
• Enhanced detection of dentinal lesions in OCT images using the RKT transformation.
  Proceedings of SPIE--the International Society for Optical Engineering 2015 Kang H, Darling CL, Tom H, Fried D
• Image-guided removal of occlusal caries lesions with a λ= 9.3-µm CO2 laser using near-IR transillumination.
  Proceedings of SPIE--the International Society for Optical Engineering 2015 Chung LC, Tom H, Chan KH, Simon JC, Fried D, Darling CL
• In vitro near-infrared imaging of natural secondary caries.
  Proceedings of SPIE--the International Society for Optical Engineering 2015 Simon JC, Lucas S, Lee R, Darling CL, Staninec M, Vanderhobli R, Pelzner R, Fried D
• Selective removal of demineralized enamel using a CO2 laser coupled with near-IR reflectance imaging.
  Proceedings of SPIE--the International Society for Optical Engineering 2015 Tom H, Chan KH, Saltiel D, Fried D
• Selective removal of dental caries with a diode-pumped Er:YAG laser.
  Proceedings of SPIE--the International Society for Optical Engineering 2015 Yan R, Chan KH, Tom H, Simon JC, Darling CL, Fried D
• Serial removal of caries lesions from tooth occlusal surfaces using near-IR image-guided IR laser ablation.
  Proceedings of SPIE--the International Society for Optical Engineering 2015 Chan KH, Tom H, Darling CL, Fried D
• A method for monitoring enamel erosion using laser irradiated surfaces and optical coherence tomography.
  Lasers in surgery and medicine 2014 Chan KH, Tom H, Darling CL, Fried D
• Automated assessment of the remineralization of artificial enamel lesions with polarization-sensitive optical coherence tomography.
  Biomedical optics express 2014 Lee RC, Kang H, Darling CL, Fried D
• Longitudinal monitoring of demineralization peripheral to orthodontic brackets using cross polarization optical coherence tomography.
  Journal of dentistry 2014 Nee A, Chan K, Kang H, Staninec M, Darling CL, Fried D
• Attenuation of near-IR light through dentin at wavelengths from 1300-1650-nm.
  Proceedings of SPIE--the International Society for Optical Engineering 2014 Chan AC, Darling CL, Chan KH, Fried D
• Automated detection of remineralization in simulated enamel lesions with PS-OCT.
  Proceedings of SPIE--the International Society for Optical Engineering 2014 Lee RC, Darling CL, Fried D
• Enhancing the detection of hidden occlusal caries lesions with OCT using high index liquids.
  Proceedings of SPIE--the International Society for Optical Engineering 2014 Kang H, Darling CL, Fried D
• High contrast optical imaging methods for image guided laser ablation of dental caries lesions.
  Proceedings of SPIE--the International Society for Optical Engineering 2014 Lamantia NR, Tom H, Chan KH, Simon JC, Darling CL, Fried D
• Monitoring the inhibition of erosion by a CO2 laser with OCT.
  Proceedings of SPIE--the International Society for Optical Engineering 2014 Chan KH, Tom H, Fried D
• Near-IR imaging of cracks in teeth.
  Proceedings of SPIE--the International Society for Optical Engineering 2014 Fried WA, Simon JC, Lucas S, Chan KH, Darling CL, Staninec M, Fried D
• Near-IR imaging of demineralization under sealants.
  Proceedings of SPIE--the International Society for Optical Engineering 2014 Tom H, Chan KH, Darling CL, Fried D
• Transillumination and reflectance probes for in vivo near-IR imaging of dental caries.
  Proceedings of SPIE--the International Society for Optical Engineering 2014 Simon JC, Lucas SA, Staninec M, Tom H, Chan KH, Darling CL, Fried D
• Analysis of enamel surface damage after selective laser ablation of composite from tooth surfaces.
  Photonics & lasers in medicine 2014 Chan KH, Hirasuna K, Fried D
• Near-infrared imaging of demineralization under sealants.
  Journal of biomedical optics 2014 Tom H, Simon JC, Chan KH, Darling CL, Fried D
• Multispectral near-IR reflectance imaging of simulated early occlusal lesions: variation of lesion contrast with lesion depth and severity.
  Lasers in surgery and medicine 2013 Simon JC, Chan KH, Darling CL, Fried D
• Use of 2D images of depth and integrated reflectivity to represent the severity of demineralization in cross-polarization optical coherence tomography.
  Journal of biophotonics 2013 Chan KH, Chan AC, Fried WA, Simon JC, Darling CL, Fried D
• High contrast reflectance imaging of simulated lesions on tooth occlusal surfaces at near-IR wavelengths.
  Lasers in surgery and medicine 2013 Fried WA, Fried D, Chan KH, Darling CL
• Clinical Monitoring of Early Caries Lesions using Cross Polarization Optical Coherence Tomography.
  Proceedings of SPIE--the International Society for Optical Engineering 2013 Fried D, Staninec M, Darling CL, Chan KH, Pelzner RB
• Imaging Early Demineralization on Tooth Occlusal Surfaces with a High Definition InGaAs Camera.
  Proceedings of SPIE--the International Society for Optical Engineering 2013 Fried WA, Fried D, Chan KH, Darling CL
• Methods for Monitoring Erosion Using Optical Coherence Tomography.
  Proceedings of SPIE--the International Society for Optical Engineering 2013 Chan KH, Chan AC, Darling CL, Fried D
• Monitoring the Remineralization of Early Simulated Lesions using a pH Cycling Model with CP-OCT.
  Proceedings of SPIE--the International Society for Optical Engineering 2013 Kang H, Chan K, Darling CL, Fried D
• Investigation of Acid-Etched CO2 Laser Ablated Enamel Surfaces Using Polarization Sensitive Optical Coherence Tomography.
  Proceedings of SPIE--the International Society for Optical Engineering 2012 Nahm BJ, Kang H, Chan K, Fried D
• Monitoring tooth demineralization using a cross polarization optical coherence tomographic system with an integrated MEMS scanner.
  Proceedings of SPIE--the International Society for Optical Engineering 2012 Fried D, Staninec M, Darling C, Kang H, Chan K
• Nondestructive Monitoring of the Repair of Natural Occlusal Lesions using Cross - Polarization Optical Coherence Tomography.
  Proceedings of SPIE--the International Society for Optical Engineering 2012 Kang H, Darling CL, Fried D
• Remineralization of Root Caries Monitored Using Cross-Polarization Optical Coherence Tomography.
  Proceedings of SPIE--the International Society for Optical Engineering 2012 Darling CL, Staninec M, Chan KH, Kang H, Fried D
• Selective Removal of Demineralization Using Near Infrared Cross Polarization Reflectance and a Carbon Dioxide Laser.
  Proceedings of SPIE--the International Society for Optical Engineering 2012 Chan KH, Fried D
• Nondestructive monitoring of the repair of enamel artificial lesions by an acidic remineralization model using polarization-sensitive optical coherence tomography.
  Dental materials : official publication of the Academy of Dental Materials 2011 Kang H, Darling CL, Fried D
• Non-destructive clinical assessment of occlusal caries lesions using near-IR imaging methods.
  Lasers in surgery and medicine 2011 Staninec M, Douglas SM, Darling CL, Chan K, Kang H, Lee RC, Fried D
• Multispectral near-IR reflectance and transillumination imaging of teeth.
  Biomedical optics express 2011 Chung S, Fried D, Staninec M, Darling CL
• Rapid and selective removal of composite from tooth surfaces with a 9.3 µm CO2 laser using spectral feedback.
  Lasers in surgery and medicine 2011 Chan KH, Hirasuna K, Fried D
• Caries inhibition in vital teeth using 9.6-μm CO2-laser irradiation.
  Journal of biomedical optics 2011 Rechmann P, Fried D, Le CQ, Nelson G, Rapozo-Hilo M, Rechmann BM, Featherstone JD
• High-speed scanning ablation of dental hard tissues with a λ = 9.3 μm CO2 laser: adhesion, mechanical strength, heat accumulation, and peripheral thermal damage.
  Journal of biomedical optics 2011 Nguyen D, Chang K, Hedayatollahnajafi S, Staninec M, Chan K, Lee R, Fried D
• In vivo Near-IR Imaging of Occlusal Lesions at 1310-nm.
  Proceedings of SPIE--the International Society for Optical Engineering 2011 Fried D, Staninec M, Darling CL, Lee C, Kang H, Chan KH
• Repair of Artificial Lesions using an Acidic Remineralization Model Monitored with Cross - Polarization Optical Coherence Tomography.
  Proceedings of SPIE--the International Society for Optical Engineering 2011 Kang H, Darling CL, Fried D
• Adhesion studies on dental enamel surfaces irradiated by a rapidly scanned carbon dioxide laser.
  Proceedings of SPIE--the International Society for Optical Engineering 2011 Chang KK, Staninec M, Chan KH, Fried D
• Near infrared imaging of teeth at wavelengths between 1200 and 1600 nm.
  Proceedings of SPIE--the International Society for Optical Engineering 2011 Chung S, Fried D, Staninec M, Darling CL
• Polarization Resolved Near-IR Imaging of Sound and Carious Dental Enamel.
  Proceedings of SPIE--the International Society for Optical Engineering 2011 Darling CL, Chan KH, Fried D
• Selective Removal of Dental Composite using a Rapidly Scanned Carbon Dioxide Laser.
  Proceedings of SPIE--the International Society for Optical Engineering 2011 Chan KH, Fried D
• Clinical assessment of early tooth demineralization using polarization sensitive optical coherence tomography.
  Lasers in surgery and medicine 2010 Louie T, Lee C, Hsu D, Hirasuna K, Manesh S, Staninec M, Darling CL, Fried D
• Nondestructive Assessment of Early Tooth Demineralization Using Cross-Polarization Optical Coherence Tomography.
  IEEE journal of selected topics in quantum electronics : a publication of the IEEE Lasers and Electro-optics Society 2010 Kang H, Jiao JJ, Lee C, Le MH, Darling CL, Fried D
• Nondestructive assessment of the severity of occlusal caries lesions with near-infrared imaging at 1310 nm.
  Journal of biomedical optics 2010 Lee C, Lee D, Darling CL, Fried D
• In vivo near-IR imaging of approximal dental decay at 1,310 nm.
  Lasers in surgery and medicine 2010 Staninec M, Lee C, Darling CL, Fried D
• Imaging Simulated Secondary Caries Lesions with Cross Polarization OCT.
  Proceedings of SPIE--the International Society for Optical Engineering 2010 Stahl J, Kang H, Fried D
• Near-IR Imaging of Thermal Changes in Enamel during Laser Ablation.
  Proceedings of SPIE--the International Society for Optical Engineering 2010 Maung LH, Lee C, Fried D
• In vitro near-infrared imaging of occlusal dental caries using germanium enhanced CMOS camera.
  Proceedings of SPIE--the International Society for Optical Engineering 2010 Lee C, Darling CL, Fried D
• Automated analysis of lesion depth and integrated reflectivity in PS-OCT scans of tooth demineralization.
  Lasers in surgery and medicine 2010 Le MH, Darling CL, Fried D
• Imaging Natural Occlusal Caries Lesions with Optical Coherence Tomography.
  Proceedings of SPIE--the International Society for Optical Engineering 2010 Douglas SM, Fried D, Darling CL
• Imaging early demineralization with PS-OCT.
  Proceedings of SPIE--the International Society for Optical Engineering 2010 Kang H, Jiao JJ, Lee C, Darling CL, Fried D
• Near-IR Polarization Imaging of Sound and Carious Dental Enamel.
  Proceedings of SPIE--the International Society for Optical Engineering 2010 Darling CL, Jiao JJ, Lee C, Kang H, Fried D
• Near-infrared image-guided laser ablation of dental decay.
  Journal of biomedical optics 2009 Tao YC, Fried D
• Nondestructive assessment of dentin demineralization using polarization-sensitive optical coherence tomography after exposure to fluoride and laser irradiation.
  Journal of biomedical materials research. Part B, Applied biomaterials 2009 Manesh SK, Darling CL, Fried D
• Polarization-sensitive optical coherence tomography for the nondestructive assessment of the remineralization of dentin.
  Journal of biomedical optics 2009 Manesh SK, Darling CL, Fried D
• Pulpal effects of enamel ablation with a microsecond pulsed lambda = 9.3-microm CO2 laser.
  Lasers in surgery and medicine 2009 Staninec M, Darling CL, Goodis HE, Pierre D, Cox DP, Fan K, Larson M, Parisi R, Hsu D, Manesh SK, Ho C, Hosseini M, Fried D
• Non-destructive measurement of demineralization & remineralization in the occlusal pits and fissures of extracted 3 molars with PS-OCT.
  Proceedings of SPIE--the International Society for Optical Engineering 2009 Lee C, Hsu DJ, Le MH, Darling CL, Fried D
• High contrast near-infrared polarized reflectance images of demineralization on tooth buccal and occlusal surfaces at lambda = 1310-nm.
  Lasers in surgery and medicine 2009 Wu J, Fried D
• An Automated Digital Microradiography System for Assessing Tooth Demineralization.
  Proceedings of SPIE--the International Society for Optical Engineering 2009 Darling CL, Le CQ, Featherstone JD, Fried D
• Dentin bond strength after ablation using a CO(2) laser operating at high pulse repetition rates.
  Proceedings of SPIE--the International Society for Optical Engineering 2009 Hedayatollahnajafi S, Staninec M, Watanabe L, Lee C, Fried D
• Methods for calculating the severity of demineralization on tooth surfaces from PS-OCT scans.
  Proceedings of SPIE--the International Society for Optical Engineering 2009 Le MH, Darling CL, Fried D
• Polarization-sensitive optical coherence tomographic imaging of artificial demineralization on exposed surfaces of tooth roots.
  Dental materials : official publication of the Academy of Dental Materials 2009 Lee C, Darling CL, Fried D
• Assessment of Dentin Remineralization with PS-OCT.
  Proceedings of SPIE--the International Society for Optical Engineering 2009 Manesh SK, Darling CL, Fried D
• Dentin caries zones: mineral, structure, and properties.
  Journal of dental research 2009 Pugach MK, Strother J, Darling CL, Fried D, Gansky SA, Marshall SJ, Marshall GW
• Near-IR Multi-modal Imaging of Natural Occlusal Lesions.
  Proceedings of SPIE--the International Society for Optical Engineering 2009 Lee D, Fried D, Darling CL
• Weakening of dentin from cracks resulting from laser irradiation.
  Dental materials : official publication of the Academy of Dental Materials 2008 Staninec M, Meshkin N, Manesh SK, Ritchie RO, Fried D
• Nondestructive assessment of the inhibition of enamel demineralization by CO2 laser treatment using polarization sensitive optical coherence tomography.
  Journal of biomedical optics 2008 Hsu DJ, Darling CL, Lachica MM, Fried D
• Near-infrared imaging of developmental defects in dental enamel.
  Journal of biomedical optics 2008 Hirasuna K, Fried D, Darling CL
• Non-destructive assessment of inhibition of demineralization in dental enamel irradiated by a lambda=9.3-microm CO2 laser at ablative irradiation intensities with PS-OCT.
  Lasers in surgery and medicine 2008 Can AM, Darling CL, Ho C, Fried D
• High-resolution PS-OCT of Enamel Remineralization.
  Proceedings of SPIE--the International Society for Optical Engineering 2008 Can AM, Darling CL, Fried D
• Imaging laser irradiated enamel surfaces with polarization sensitive optical coherence tomography.
  Proceedings of SPIE--the International Society for Optical Engineering 2008 Hsu DJ, Darling CL, Fried D
• Selective Removal of Natural Occlusal Caries by Coupling Near-infrared Imaging with a CO(2) Laser.
  Proceedings of SPIE--the International Society for Optical Engineering 2008 Tao YC, Fried D
• Real-time near IR (1310 nm) imaging of CO2 laser ablation of enamel.
  Optics express 2008 Darling CL, Fried D
• Near-IR imaging of Erbium Laser Ablation with a Water Spray.
  Proceedings of SPIE--the International Society for Optical Engineering 2008 Darling CL, Maffei ME, Fried WA, Fried D
• Ablation of Dental Hard Tissues with a Microsecond Pulsed Carbon Dioxide Laser Operating at 9.3-μm with an Integrated Scanner.
  Proceedings of SPIE--the International Society for Optical Engineering 2008 Assa S, Meyer S, Fried D
• Imaging natural and artificial demineralization on dentin surfaces with polarization sensitive optical coherence tomography.
  Proceedings of SPIE--the International Society for Optical Engineering 2008 Manesh SK, Darling CL, Fried D
• Nondestructive measurement of the inhibition of demineralization on smooth surfaces using polarization-sensitive optical coherence tomography.
  Lasers in surgery and medicine 2007 Chong SL, Darling CL, Fried D
• Near-infrared image-guided laser ablation of artificial caries lesions.
  Proceedings of SPIE--the International Society for Optical Engineering 2007 Tao YC, Fan K, Fried D
• Rapid and conservative ablation and modification of enamel, dentin, and alveolar bone using a high repetition rate transverse excited atmospheric pressure CO2 laser operating at lambda=9.3 micro.
  Journal of biomedical optics 2006 Fan K, Bell P, Fried D
• Adhesion of composite to enamel and dentin surfaces irradiated by IR laser pulses of 0.5-35 micros duration.
  Journal of biomedical materials research. Part B, Applied biomaterials 2006 Staninec M, Gardner AK, Le CQ, Sarma AV, Fried D
• Dissolution studies of bovine dental enamel surfaces modified by high-speed scanning ablation with a lambda = 9.3-microm TEA CO(2) laser.
  Lasers in surgery and medicine 2006 Fried D, Featherstone JD, Le CQ, Fan K
• Remineralization of enamel caries can decrease optical reflectivity.
  Journal of dental research 2006 Jones RS, Fried D
• Light scattering properties of natural and artificially demineralized dental enamel at 1310 nm.
  Journal of biomedical optics 2006 Darling CL, Huynh GD, Fried D
• Imaging artificial caries on the occlusal surfaces with polarization-sensitive optical coherence tomography.
  Caries research 2006 Jones RS, Darling CL, Featherstone JD, Fried D
• Remineralization of in vitro dental caries assessed with polarization-sensitive optical coherence tomography.
  Journal of biomedical optics 2006 Jones RS, Darling CL, Featherstone JD, Fried D
• Early caries imaging and monitoring with near-infrared light.
  Dental clinics of North America 2005 Fried D, Featherstone JD, Darling CL, Jones RS, Ngaotheppitak P, Bühler CM
• Measurement of the severity of natural smooth surface (interproximal) caries lesions with polarization sensitive optical coherence tomography.
  Lasers in surgery and medicine 2005 Ngaotheppitak P, Darling CL, Fried D
• Imaging of occlusal dental caries (decay) with near-IR light at 1310-nm.
  Optics express 2005 Bühler C, Ngaotheppitak P, Fried D
• Selective removal of composite sealants with near-ultraviolet laser pulses of nanosecond duration.
  Journal of biomedical optics 2005 Louie TM, Jones RS, Sarma AV, Fried D
• Transmission of Q-switched erbium:YSGG (lambda=2.79 microm) and erbium:YAG (lambda=2.94 microm) laser radiation through germanium oxide and sapphire optical fibres at high pulse energies.
  Lasers in medical science 2004 Fried NM, Yang Y, Chaney CA, Fried D
• Imaging artificial caries under composite sealants and restorations.
  Journal of biomedical optics 2004 Jones RS, Staninec M, Fried D
• Peripheral thermal and mechanical damage to dentin with microsecond and sub-microsecond 9.6 microm, 2.79 microm, and 0.355 microm laser pulses.
  Lasers in surgery and medicine 2004 Dela Rosa A, Sarma AV, Le CQ, Jones RS, Fried D
• Pulpal safety of 9.6 microm TEA CO2 laser used for caries prevention.
  Lasers in surgery and medicine 2004 Goodis HE, Fried D, Gansky S, Rechmann P, Featherstone JD
• Selective targeting of protein, water, and mineral in dentin using UV and IR pulse lasers: the effect on the bond strength to composite restorative materials.
  Lasers in surgery and medicine 2004 Sheth KK, Staninec M, Sarma AV, Fried D
• Near-infrared transillumination at 1310-nm for the imaging of early dental decay.
  Optics express 2003 Jones R, Huynh G, Jones G, Fried D
• Influence of an optically thick water layer on the bond-strength of composite resin to dental enamel after IR laser ablation.
  Lasers in surgery and medicine 2003 Staninec M, Xie J, Le CQ, Fried D
• Irradiation of dental enamel with Q-switched lambda = 355-nm laser pulses: surface morphology, fluoride adsorption, and adhesion to composite resin.
  Lasers in surgery and medicine 2003 Wheeler CR, Fried D, Featherstone JD, Watanabe LG, Le CQ
• Mechanism of water augmentation during IR laser ablation of dental enamel.
  Lasers in surgery and medicine 2002 Fried D, Ashouri N, Breunig T, Shori R
• Selective ablation of surface enamel caries with a pulsed Nd:YAG dental laser.
  Lasers in surgery and medicine 2002 Harris DM, White JM, Goodis H, Arcoria CJ, Simon J, Carpenter WM, Fried D, Burkart J, Yessik M, Myers T
• Selective removal of residual composite from dental enamel surfaces using the third harmonic of a Q-switched Nd:YAG laser.
  Lasers in surgery and medicine 2002 Alexander R, Xie J, Fried D
• Dental hard tissue modification and removal using sealed transverse excited atmospheric-pressure lasers operating at lambda=9.6 and 10.6 microm.
  Journal of biomedical optics 2001 Fried D, Ragadio J, Akrivou M, Featherstone JD, Murray MW, Dickenson KM
• Selective ablation of orthodontic composite by using sub-microsecond IR laser pulses with optical feedback.
  Lasers in surgery and medicine 2000 Dumore T, Fried D
• Modeling the modification depth of carbon dioxide laser-treated dental enamel.
  Lasers in surgery and medicine 1999 Zuerlein MJ, Fried D, Featherstone JD
• CO2 laser inhibitor of artificial caries-like lesion progression in dental enamel.
  Journal of dental research 1998 Featherstone JD, Barrett-Vespone NA, Fried D, Kantorowitz Z, Seka W
• Permanent and transient changes in the reflectance of CO2 laser-irradiated dental hard tissues at lambda = 9.3, 9.6, 10.3, and 10.6 microns and at fluences of 1-20 J/cm2.
  Lasers in surgery and medicine 1997 Fried D, Glena RE, Featherstone JD, Seka W