Danilo Bernardo, JR, MD
Assistant Professor
Neurology
School of Medicine

Dr. Bernardo is a pediatric neurologist and epileptologist in the Department of Neurology at UCSF. He has clinical interests in the treatment of early childhood-onset epilepsy, drug resistant epilepsy, and in surgical treatments for drug resistant epilepsy. His research involves the development of computational approaches to guide the diagnosis and treatment of childhood forms of epilepsy.

Education & Training

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• Pediatric Epilepsy UCLA 2019
• Clinical Neurophysiology UCLA 2018
• Child Neurology UCLA 2017
• Neurology University of North Carolina 2014
• MD University of North Carolina 2010

Publications (12)

Top publication keywords:
WakefulnessIntellectual DisabilitySeizuresVisual PerceptionSpasms, InfantileLearningEpilepsies, PartialBrain WavesTuberous SclerosisElectroencephalographyScalpPhosphotransferases (Alcohol Group Acceptor)BrainWavelet AnalysisEpilepsy

• Automated preprocessing and phase-amplitude coupling analysis of scalp EEG discriminates infantile spasms from controls during wakefulness.
  Epilepsy research 2021 Miyakoshi M, Nariai H, Rajaraman RR, Bernardo D, Shrey DW, Lopour BA, Sim MS, Staba RJ, Hussain SA
• PIGG variant pathogenicity assessment reveals characteristic features within 19 families.
  Genetics in medicine : official journal of the American College of Medical Genetics 2021 Tremblay-Laganière C, Maroofian R, Nguyen TTM, Karimiani EG, Kirmani S, Akbar F, Ibrahim S, Afroze B, Doosti M, Ashrafzadeh F, Babaei M, Efthymiou S, Christoforou M, Sultan T, Ladda RL, McLaughlin HM,…
• Scalp EEG interictal high frequency oscillations as an objective biomarker of infantile spasms.
  Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology 2020 Nariai H, Hussain SA, Bernardo D, Motoi H, Sonoda M, Kuroda N, Asano E, Nguyen JC, Elashoff D, Sankar R, Bragin A, Staba RJ, Wu JY
• Interictal scalp fast ripple occurrence and high frequency oscillation slow wave coupling in epileptic spasms.
  Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology 2020 Bernardo D, Nariai H, Hussain SA, Sankar R, Wu JY
• Prospective observational study: Fast ripple localization delineates the epileptogenic zone.
  Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology 2019 Nariai H, Hussain SA, Bernardo D, Fallah A, Murata KK, Nguyen JC, Rajaraman RR, Rao LM, Matsumoto JH, Lerner JT, Salamon N, Elashoff D, Sankar R, Wu JY

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• Interrater reliability in visual identification of interictal high-frequency oscillations on electrocorticography and scalp EEG.
  Epilepsia open 2018 Nariai H, Wu JY, Bernardo D, Fallah A, Sankar R, Hussain SA
• Automated Detection of High Frequency Oscillations in Human Scalp Electroencephalogram.
  Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference 2018 Charupanit K, Nunez MD, Bernardo D, Bebin M, Krueger DA, Northrup H, Sahin M, Wu JY, Lopour BA
• Visual and semi-automatic non-invasive detection of interictal fast ripples: A potential biomarker of epilepsy in children with tuberous sclerosis complex.
  Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology 2018 Bernardo D, Nariai H, Hussain SA, Sankar R, Salamon N, Krueger DA, Sahin M, Northrup H, Bebin EM, Wu JY, UCLA Pediatric Epilepsy Group, TACERN Study Group
• Toxoplasmic encephalitis during mycophenolate mofetil immunotherapy of neuromuscular disease.
  Neurology(R) neuroimmunology & neuroinflammation 2015 Bernardo DR, Chahin N
• Unsupervised learning of electrocorticography motifs with binary descriptors of wavelet features and hierarchical clustering.
  Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference 2014 Pluta T, Bernardo R, Shin HW, Bernardo DR
• Downregulation of NR3A-containing NMDARs is required for synapse maturation and memory consolidation.
  Neuron 2009 Roberts AC, Díez-García J, Rodriguiz RM, López IP, Luján R, Martínez-Turrillas R, Picó E, Henson MA, Bernardo DR, Jarrett TM, Clendeninn DJ, López-Mascaraque L, Feng G, Lo DC, Wesseling JF, Wetsel WC,…
• Ube3a is required for experience-dependent maturation of the neocortex.
  Nature neuroscience 2009 Yashiro K, Riday TT, Condon KH, Roberts AC, Bernardo DR, Prakash R, Weinberg RJ, Ehlers MD, Philpot BD