Cynthia Kenyon, PhD
Professor
Biochemistry and Biophysics
School of Medicine
Cynthia Kenyon graduated valedictorian in chemistry and biochemistry from the University of Georgia in 1976. She received her PhD from MIT in 1981, where, in Graham Walker’s laboratory, she was the first to look for genes on the basis of their expression profiles, discovering that DNA damaging agents activate a battery of DNA repair genes in E. coli.
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She then did postdoctoral studies with Nobel laureate Sydney Brenner at the MRC Laboratory of Molecular Biology in Cambridge, UK, studying the development of C. elegans. Since 1986 she has been at the University of California, San Francisco, where she was the Herbert Boyer Distinguished Professor of Biochemistry and Biophysics and is now an American Cancer Society Professor. In 1993, Kenyon and colleagues’ discovery that a single-gene mutation could double the lifespan of C. elegans sparked an intensive study of the molecular biology of aging. These findings have now led to the discovery that an evolutionarily conserved hormone signaling system controls aging in other organisms as well, including mammals. Dr. Kenyon has received many honors and awards for her findings. She is a member of the US National Academy of Sciences, the American Academy of Arts and Sciences, and the Institute of Medicine and she is a past president of the Genetics Society of America. She is now the director of the Hillblom Center for the Biology of Aging at UCSF.
Websites
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- Kenyon Lab at UCSF (kenyonlab.ucsf.edu)
- Cynthia Kenyon: Future - Ageing - Facing the Challenge (coe.ucsf.edu)
Videos
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Grants and Projects
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- Signals from the reproductive system that regulate aging in C. elegans, NIH, 2009-2020
- Genetic Analysis of Aging in C. elegans, NIH, 1994-2020
- Translational Studies Linking Aging and Cancer, NIH, 2013-2019
- Human Gene Knockdowns that May Extend Lifespan, NIH, 2012-2018
- Bio-Organic Biomedical Mass Spectrometry Resource, NIH, 1982-2015
- Genetic Control of Aging in C. elegans, NIH, 1994-2014
- Lifespan regulation by the DAF-12 nuclear hormone receptor in C. elegans, NIH, 2002-2012
- Aging and Neurodegenerative Diseases, NIH, 2002-2008
- Antero Posterior Pattern Formation in C Elegans, NIH, 1986-2002
Publications (133)
Top publication keywords:
Insulin-Like Growth Factor ITranscription FactorsAgingCaenorhabditis elegans ProteinsProteostasisCaenorhabditisCaenorhabditis elegansSignal TransductionLongevityGenes, HelminthReceptor, InsulinHelminth ProteinsGerm CellsGenes, HomeoboxOocytes
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Individual cell types in C. elegans age differently and activate distinct cell-protective responses.
Cell reports 2023 Roux AE, Yuan H, Podshivalova K, Hendrickson D, Kerr R, Kenyon C, Kelley D -
LAMP2A, and other chaperone-mediated autophagy related proteins, do not decline with age in genetically heterogeneous UM-HET3 mice.
Aging 2023 Zhang KK, Zhang P, Kodur A, Erturk I, Burns CM, Kenyon C, Miller RA, Endicott SJ -
The C. elegans Observatory: High-throughput exploration of behavioral aging.
Frontiers in aging 2022 Kerr RA, Roux AE, Goudeau J, Kenyon C -
Diverse partial reprogramming strategies restore youthful gene expression and transiently suppress cell identity.
Cell systems 2022 Roux AE, Zhang C, Paw J, Zavala-Solorio J, Malahias E, Vijay T, Kolumam G, Kenyon C, Kimmel JC -
Novel insights from a multiomics dissection of the Hayflick limit.
eLife 2022 Chan M, Yuan H, Soifer I, Maile TM, Wang RY, Ireland A, O'Brien JJ, Goudeau J, Chan LJG, Vijay T, Freund A, Kenyon C, Bennett BD, McAllister FE, Kelley DR, Roy M, Cohen RL, Levinson AD, Botstein D, …
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The naked truth: a comprehensive clarification and classification of current 'myths' in naked mole-rat biology.
Biological reviews of the Cambridge Philosophical Society 2021 Buffenstein R, Amoroso V, Andziak B, Avdieiev S, Azpurua J, Barker AJ, Bennett NC, Brieño-Enríquez MA, Bronner GN, Coen C, Delaney MA, Dengler-Crish CM, Edrey YH, Faulkes CG, Frankel D, Friedlander G,… -
Split-wrmScarlet and split-sfGFP: tools for faster, easier fluorescent labeling of endogenous proteins in Caenorhabditis elegans.
Genetics 2021 Goudeau J, Sharp CS, Paw J, Savy L, Leonetti MD, York AG, Updike DL, Kenyon C, Ingaramo M -
A genetic screen identifies new steps in oocyte maturation that enhance proteostasis in the immortal germ lineage.
eLife 2021 Samaddar M, Goudeau J, Sanchez M, Hall DH, Bohnert KA, Ingaramo M, Kenyon C -
Application of Transcriptional Gene Modules to Analysis of Caenorhabditis elegans' Gene Expression Data.
G3 (Bethesda, Md.) 2020 Cary M, Podshivalova K, Kenyon C -
Addendum: A lysosomal switch triggers proteostasis renewal in the immortal C. elegans germ lineage.
Nature 2020 Goudeau J, Samaddar M, Bohnert KA, Kenyon C -
Stress Resistance Screen in a Human Primary Cell Line Identifies Small Molecules That Affect Aging Pathways and Extend Caenorhabditis elegans' Lifespan.
G3 (Bethesda, Md.) 2020 Zhang P, Zhai Y, Cregg J, Ang KK, Arkin M, Kenyon C -
X Chromosome Domain Architecture Regulates Caenorhabditis elegans Lifespan but Not Dosage Compensation.
Developmental cell 2019 Anderson EC, Frankino PA, Higuchi-Sanabria R, Yang Q, Bian Q, Podshivalova K, Shin A, Kenyon C, Dillin A, Meyer BJ -
Containing a measles outbreak in Minnesota, 2017: methods and challenges.
Perspectives in public health 2019 Banerjee E, Griffith J, Kenyon C, Christianson B, Strain A, Martin K, McMahon M, Bagstad E, Laine E, Hardy K, Grilli G, Walters J, Dunn D, Roddy M, Ehresmann K -
Sydney Brenner (1927-2019).
Science (New York, N.Y.) 2019 Kenyon C -
The mTOR Target S6 Kinase Arrests Development in Caenorhabditis elegans When the Heat-Shock Transcription Factor Is Impaired.
Genetics 2018 Chisnell P, Parenteau TR, Tank E, Ashrafi K, Kenyon C -
Canadian Surgery Forum 2018: St. John's, NL Sept. 13-15, 2018.
Canadian journal of surgery. Journal canadien de chirurgie 2018 Jayaraman S, Lee L, Mata J, Droeser R, Kaneva P, Liberman S, Charlebois P, Stein B, Fried G, Feldman L, Schellenberg M, Inaba K, Cheng V, Bardes J, Lam L, Benjamin E, Matsushima K, Demetriades D, … -
Silencing the ASI gustatory neuron pair extends lifespan.
microPublication biology 2018 Chisnell P, Kenyon C -
Silencing the ASI gustatory neuron pair increases expression of the stress-resistance gene sod-3 in a daf-16 and daf-3 independent manner.
microPublication biology 2018 Chisnell P, Kenyon C -
A lysosomal switch triggers proteostasis renewal in the immortal C. elegans germ lineage.
Nature 2017 Bohnert KA, Kenyon C -
How a Mutation that Slows Aging Can Also Disproportionately Extend End-of-Life Decrepitude.
Cell reports 2017 Podshivalova K, Kerr RA, Kenyon C -
Deep Proteome Analysis Identifies Age-Related Processes in C. elegans.
Cell systems 2016 Narayan V, Ly T, Pourkarimi E, Murillo AB, Gartner A, Lamond AI, Kenyon C -
Reversible Age-Related Phenotypes Induced during Larval Quiescence in C. elegans.
Cell metabolism 2016 Roux AE, Langhans K, Huynh W, Kenyon C -
Roles for ROS and hydrogen sulfide in the longevity response to germline loss in Caenorhabditis elegans.
Proceedings of the National Academy of Sciences of the United States of America 2016 Wei Y, Kenyon C -
Micro-proteomics with iterative data analysis: Proteome analysis in C. elegans at the single worm level.
Proteomics 2016 Bensaddek D, Narayan V, Nicolas A, Murillo AB, Gartner A, Kenyon CJ, Lamond AI -
Interventions to Slow Aging in Humans: Are We Ready?
Aging cell 2015 Longo VD, Antebi A, Bartke A, Barzilai N, Brown-Borg HM, Caruso C, Curiel TJ, de Cabo R, Franceschi C, Gems D, Ingram DK, Johnson TE, Kennedy BK, Kenyon C, Klein S, Kopchick JJ, Lepperdinger G, Madeo … -
A shift to organismal stress resistance in programmed cell death mutants.
PLoS genetics 2013 Judy ME, Nakamura A, Huang A, Grant H, McCurdy H, Weiberth KF, Gao F, Coppola G, Kenyon C, Kao AW -
The ire-1 ER stress-response pathway is required for normal secretory-protein metabolism in C. elegans.
Journal of cell science 2013 Safra M, Ben-Hamo S, Kenyon C, Henis-Korenblit S -
Direct and indirect gene regulation by a life-extending FOXO protein in C. elegans: roles for GATA factors and lipid gene regulators.
Cell metabolism 2013 Zhang P, Judy M, Lee SJ, Kenyon C -
Genes that act downstream of sensory neurons to influence longevity, dauer formation, and pathogen responses in Caenorhabditis elegans.
PLoS genetics 2012 Gaglia MM, Jeong DE, Ryu EA, Lee D, Kenyon C, Lee SJ -
Could a hormone point the way to life extension?
eLife 2012 Kenyon C -
New genes that extend Caenorhabditis elegans' lifespan in response to reproductive signals.
Aging cell 2011 McCormick M, Chen K, Ramaswamy P, Kenyon C -
The thrombospondin repeat containing protein MIG-21 controls a left-right asymmetric Wnt signaling response in migrating C. elegans neuroblasts.
Developmental biology 2011 Middelkoop TC, Williams L, Yang PT, Luchtenberg J, Betist MC, Ji N, van Oudenaarden A, Kenyon C, Korswagen HC -
QnAs with Cynthia Kenyon.
Proceedings of the National Academy of Sciences of the United States of America 2011 Kenyon C -
Canadian Surgery Forum: Abstracts of presentations to the Annual Meetings of the Canadian Association of Bariatric Physicians and Surgeons, Canadian Association of General Surgeons, Canadian Association of Thoracic Surgeons, Canadian Hepato-Pancreato-Biliary Society, Canadian Society of Surgical Oncology, Canadian Society of Colon and Rectal Surgeons, London, Ont. Sept. 15-18, 2011.
Canadian journal of surgery. Journal canadien de chirurgie 2011 Chiu JC, Shi X, Karmali S, Birch DW, Apriasz I, Alkhamesi NA, Lal A, Schlachta CM, Christou NV, Elkassem S, Lindsay D, Smith L, Sullivan P, Sockalingam S, Hawa R, Wnuk S, Jackson T, Okrainec A, Fayez … -
Spontaneous age-related neurite branching in Caenorhabditis elegans.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2011 Tank EM, Rodgers KE, Kenyon C -
A neurodegenerative disease mutation that accelerates the clearance of apoptotic cells.
Proceedings of the National Academy of Sciences of the United States of America 2011 Kao AW, Eisenhut RJ, Martens LH, Nakamura A, Huang A, Bagley JA, Zhou P, de Luis A, Neukomm LJ, Cabello J, Farese RV, Kenyon C -
The first long-lived mutants: discovery of the insulin/IGF-1 pathway for ageing.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences 2011 Kenyon C -
Liquorice and glycyrrhetinic acid increase DHEA and deoxycorticosterone levels in vivo and in vitro by inhibiting adrenal SULT2A1 activity.
Molecular and cellular endocrinology 2010 Al-Dujaili EA, Kenyon CJ, Nicol MR, Mason JI -
Inhibition of respiration extends C. elegans life span via reactive oxygen species that increase HIF-1 activity.
Current biology : CB 2010 Lee SJ, Hwang AB, Kenyon C -
The somatic reproductive tissues of C. elegans promote longevity through steroid hormone signaling.
PLoS biology 2010 Yamawaki TM, Berman JR, Suchanek-Kavipurapu M, McCormick M, Gaglia MM, Lee SJ, Kenyon C -
Widespread protein aggregation as an inherent part of aging in C. elegans.
PLoS biology 2010 David DC, Ollikainen N, Trinidad JC, Cary MP, Burlingame AL, Kenyon C -
A pathway that links reproductive status to lifespan in Caenorhabditis elegans.
Annals of the New York Academy of Sciences 2010 Kenyon C -
Insulin/IGF-1 signaling mutants reprogram ER stress response regulators to promote longevity.
Proceedings of the National Academy of Sciences of the United States of America 2010 Henis-Korenblit S, Zhang P, Hansen M, McCormick M, Lee SJ, Cary M, Kenyon C -
The genetics of ageing.
Nature 2010 Kenyon CJ -
Impact papers on aging in 2009.
Aging 2010 Blagosklonny MV, Campisi J, Sinclair DA, Bartke A, Blasco MA, Bonner WM, Bohr VA, Brosh RM, Brunet A, Depinho RA, Donehower LA, Finch CE, Finkel T, Gorospe M, Gudkov AV, Hall MN, Hekimi S, Helfand SL,… -
Glucose shortens the life span of C. elegans by downregulating DAF-16/FOXO activity and aquaporin gene expression.
Cell metabolism 2009 Lee SJ, Murphy CT, Kenyon C -
A transcription elongation factor that links signals from the reproductive system to lifespan extension in Caenorhabditis elegans.
PLoS genetics 2009 Ghazi A, Henis-Korenblit S, Kenyon C -
Stimulation of movement in a quiescent, hibernation-like form of Caenorhabditis elegans by dopamine signaling.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2009 Gaglia MM, Kenyon C -
Regulation of the longevity response to temperature by thermosensory neurons in Caenorhabditis elegans.
Current biology : CB 2009 Lee SJ, Kenyon C -
A regulated response to impaired respiration slows behavioral rates and increases lifespan in Caenorhabditis elegans.
PLoS genetics 2009 Cristina D, Cary M, Lunceford A, Clarke C, Kenyon C -
A role for autophagy in the extension of lifespan by dietary restriction in C. elegans.
PLoS genetics 2008 Hansen M, Chandra A, Mitic LL, Onken B, Driscoll M, Kenyon C -
Distinct activities of the germline and somatic reproductive tissues in the regulation of Caenorhabditis elegans' longevity.
Genetics 2008 Yamawaki TM, Arantes-Oliveira N, Berman JR, Zhang P, Kenyon C -
Tissue entrainment by feedback regulation of insulin gene expression in the endoderm of Caenorhabditis elegans.
Proceedings of the National Academy of Sciences of the United States of America 2007 Murphy CT, Lee SJ, Kenyon C -
DAF-16/FOXO targets genes that regulate tumor growth in Caenorhabditis elegans.
Nature genetics 2007 Pinkston-Gosse J, Kenyon C -
Caenorhabditis elegans integrates food and reproductive signals in lifespan determination.
Aging cell 2007 Crawford D, Libina N, Kenyon C -
Regulation of Caenorhabditis elegans lifespan by a proteasomal E3 ligase complex.
Proceedings of the National Academy of Sciences of the United States of America 2007 Ghazi A, Henis-Korenblit S, Kenyon C -
A steroid hormone that extends the lifespan of Caenorhabditis elegans.
Aging cell 2007 Broué F, Liere P, Kenyon C, Baulieu EE -
Lifespan extension by conditions that inhibit translation in Caenorhabditis elegans.
Aging cell 2007 Hansen M, Taubert S, Crawford D, Libina N, Lee SJ, Kenyon C -
Mutations that increase the life span of C. elegans inhibit tumor growth.
Science (New York, N.Y.) 2006 Pinkston JM, Garigan D, Hansen M, Kenyon C -
Enrichment of regulatory motifs upstream of predicted DAF-16 targets.
Nature genetics 2006 Kenyon C, Murphy CT -
Germ-cell loss extends C. elegans life span through regulation of DAF-16 by kri-1 and lipophilic-hormone signaling.
Cell 2006 Berman JR, Kenyon C -
The two isoforms of the Caenorhabditis elegans leukocyte-common antigen related receptor tyrosine phosphatase PTP-3 function independently in axon guidance and synapse formation.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2005 Ackley BD, Harrington RJ, Hudson ML, Williams L, Kenyon CJ, Chisholm AD, Jin Y -
New genes tied to endocrine, metabolic, and dietary regulation of lifespan from a Caenorhabditis elegans genomic RNAi screen.
PLoS genetics 2005 Hansen M, Hsu AL, Dillin A, Kenyon C -
The roles of two C. elegans HOX co-factor orthologs in cell migration and vulva development.
Development (Cambridge, England) 2005 Yang L, Sym M, Kenyon C -
The plasticity of aging: insights from long-lived mutants.
Cell 2005 Kenyon C -
Comparing genomic expression patterns across species identifies shared transcriptional profile in aging.
Nature genetics 2004 McCarroll SA, Murphy CT, Zou S, Pletcher SD, Chin CS, Jan YN, Kenyon C, Bargmann CI, Li H -
Regulation of C. elegans longevity by specific gustatory and olfactory neurons.
Neuron 2004 Alcedo J, Kenyon C -
My adventures with genes from the fountain of youth.
Harvey lectures 2004 Kenyon C -
Tissue-specific activities of C. elegans DAF-16 in the regulation of lifespan.
Cell 2003 Libina N, Berman JR, Kenyon C -
Healthy animals with extreme longevity.
Science (New York, N.Y.) 2003 Arantes-Oliveira N, Berman JR, Kenyon C -
Identification of genes that regulate a left-right asymmetric neuronal migration in Caenorhabditis elegans.
Genetics 2003 Ch'ng Q, Williams L, Lie YS, Sym M, Whangbo J, Kenyon C -
Genes that act downstream of DAF-16 to influence the lifespan of Caenorhabditis elegans.
Nature 2003 Murphy CT, McCarroll SA, Bargmann CI, Fraser A, Kamath RS, Ahringer J, Li H, Kenyon C -
Regulation of aging and age-related disease by DAF-16 and heat-shock factor.
Science (New York, N.Y.) 2003 Hsu AL, Murphy CT, Kenyon C -
Rates of behavior and aging specified by mitochondrial function during development.
Science (New York, N.Y.) 2002 Dillin A, Hsu AL, Arantes-Oliveira N, Lehrer-Graiwer J, Hsin H, Fraser AG, Kamath RS, Ahringer J, Kenyon C -
Genetic analysis of tissue aging in Caenorhabditis elegans: a role for heat-shock factor and bacterial proliferation.
Genetics 2002 Garigan D, Hsu AL, Fraser AG, Kamath RS, Ahringer J, Kenyon C -
The zinc finger protein REF-2 functions with the Hox genes to inhibit cell fusion in the ventral epidermis of C. elegans.
Development (Cambridge, England) 2002 Alper S, Kenyon C -
Regulation of life-span by germ-line stem cells in Caenorhabditis elegans.
Science (New York, N.Y.) 2002 Arantes-Oliveira N, Apfeld J, Dillin A, Kenyon C -
Regulation of Longevity by Insulin/Igf-1 Signaling, Sensory Neurons and the Germline in the Nematode C. Elegans.
TheScientificWorldJournal 2001 Kenyon C -
REF-1, a protein with two bHLH domains, alters the pattern of cell fusion in C. elegans by regulating Hox protein activity.
Development (Cambridge, England) 2001 Alper S, Kenyon C -
A conserved regulatory system for aging.
Cell 2001 Kenyon C -
Genetic pathways that regulate ageing in model organisms.
Nature 2000 Guarente L, Kenyon C -
Establishment of left/right asymmetry in neuroblast migration by UNC-40/DCC, UNC-73/Trio and DPY-19 proteins in C. elegans.
Development (Cambridge, England) 2000 Honigberg L, Kenyon C -
Multiple levels of regulation specify the polarity of an asymmetric cell division in C. elegans.
Development (Cambridge, England) 2000 Whangbo J, Harris J, Kenyon C -
Regulation of lifespan by sensory perception in Caenorhabditis elegans.
Nature 1999 Apfeld J, Kenyon C -
A Wnt signaling system that specifies two patterns of cell migration in C. elegans.
Molecular cell 1999 Whangbo J, Kenyon C -
egl-27 generates anteroposterior patterns of cell fusion in C. elegans by regulating Hox gene expression and Hox protein function.
Development (Cambridge, England) 1999 Ch'ng Q, Kenyon C -
MIG-13 positions migrating cells along the anteroposterior body axis of C. elegans.
Cell 1999 Sym M, Robinson N, Kenyon C -
Signals from the reproductive system regulate the lifespan of C. elegans.
Nature 1999 Hsin H, Kenyon C -
EGL-27 is similar to a metastasis-associated factor and controls cell polarity and cell migration in C. elegans.
Development (Cambridge, England) 1999 Herman MA, Ch'ng Q, Hettenbach SM, Ratliff TM, Kenyon C, Herman RK -
Hox gene expression in a single Caenorhabditis elegans cell is regulated by a caudal homolog and intercellular signals that inhibit wnt signaling.
Development (Cambridge, England) 1999 Hunter CP, Harris JM, Maloof JN, Kenyon C -
A Wnt signaling pathway controls hox gene expression and neuroblast migration in C. elegans.
Development (Cambridge, England) 1999 Maloof JN, Whangbo J, Harris JM, Jongeward GD, Kenyon C -
Cell nonautonomy of C. elegans daf-2 function in the regulation of diapause and life span.
Cell 1998 Apfeld J, Kenyon C -
The beta-catenin homolog BAR-1 and LET-60 Ras coordinately regulate the Hox gene lin-39 during Caenorhabditis elegans vulval development.
Development (Cambridge, England) 1998 Eisenmann DM, Maloof JN, Simske JS, Kenyon C, Kim SK -
Analysis of a Caenorhabditis elegans Twist homolog identifies conserved and divergent aspects of mesodermal patterning.
Genes & development 1998 Harfe BD, Vaz Gomes A, Kenyon C, Liu J, Krause M, Fire A -
StAR protein is expressed in both medulla and cortex of the bovine and rat adrenal gland.
Endocrine research 1998 Lo YC, Brett L, Kenyon CJ, Morley SD, Mason JI, Williams BC -
The Hox gene lin-39 is required during C. elegans vulval induction to select the outcome of Ras signaling.
Development (Cambridge, England) 1998 Maloof JN, Kenyon C -
daf-16: An HNF-3/forkhead family member that can function to double the life-span of Caenorhabditis elegans.
Science (New York, N.Y.) 1997 Lin K, Dorman JB, Rodan A, Kenyon C -
Role of a new Rho family member in cell migration and axon guidance in C. elegans.
Cell 1997 Zipkin ID, Kindt RM, Kenyon CJ -
The role of lin-22, a hairy/enhancer of split homolog, in patterning the peripheral nervous system of C. elegans.
Development (Cambridge, England) 1997 Wrischnik LA, Kenyon CJ -
Isolation of actin-associated proteins from Caenorhabditis elegans oocytes and their localization in the early embryo.
The EMBO journal 1997 Aroian RV, Field C, Pruliere G, Kenyon C, Alberts BM -
The dance of the Hox genes: patterning the anteroposterior body axis of Caenorhabditis elegans.
Cold Spring Harbor symposia on quantitative biology 1997 Kenyon CJ, Austin J, Costa M, Cowing DW, Harris JM, Honigberg L, Hunter CP, Maloof JN, Muller-Immerglück MM, Salser SJ, Waring DA, Wang BB, Wrischnik LA -
Spatial and temporal controls target pal-1 blastomere-specification activity to a single blastomere lineage in C. elegans embryos.
Cell 1996 Hunter CP, Kenyon C -
Neuronal cell migration in C. elegans: regulation of Hox gene expression and cell position.
Development (Cambridge, England) 1996 Harris J, Honigberg L, Robinson N, Kenyon C -
Correct Hox gene expression established independently of position in Caenorhabditis elegans.
Nature 1996 Cowing D, Kenyon C -
Genes affecting sensitivity to serotonin in Caenorhabditis elegans.
Genetics 1996 Schafer WR, Sanchez BM, Kenyon CJ -
A C. elegans Hox gene switches on, off, on and off again to regulate proliferation, differentiation and morphogenesis.
Development (Cambridge, England) 1996 Salser SJ, Kenyon C -
Ponce d'elegans: genetic quest for the fountain of youth.
Cell 1996 Kenyon C -
The age-1 and daf-2 genes function in a common pathway to control the lifespan of Caenorhabditis elegans.
Genetics 1995 Dorman JB, Albinder B, Shroyer T, Kenyon C -
Specification of anteroposterior cell fates in Caenorhabditis elegans by Drosophila Hox proteins.
Nature 1995 Hunter CP, Kenyon C -
A perfect vulva every time: gradients and signaling cascades in C. elegans.
Cell 1995 Kenyon C -
A calcium-channel homologue required for adaptation to dopamine and serotonin in Caenorhabditis elegans.
Nature 1995 Schafer WR, Kenyon CJ -
Characterization of beta pat-3 heterodimers, a family of essential integrin receptors in C. elegans.
The Journal of cell biology 1995 Gettner SN, Kenyon C, Reichardt LF -
If birds can fly, why can't we? Homeotic genes and evolution.
Cell 1994 Kenyon C -
Patterning C. elegans: homeotic cluster genes, cell fates and cell migrations.
Trends in genetics : TIG 1994 Salser SJ, Kenyon C -
Developmental timekeeping. Marking time with antisense.
Current biology : CB 1994 Austin J, Kenyon C -
Cell contact regulates neuroblast formation in the Caenorhabditis elegans lateral epidermis.
Development (Cambridge, England) 1994 Austin J, Kenyon C -
A C. elegans mutant that lives twice as long as wild type.
Nature 1993 Kenyon C, Chang J, Gensch E, Rudner A, Tabtiang R -
Serotonin-deficient mutants and male mating behavior in the nematode Caenorhabditis elegans.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1993 Loer CM, Kenyon CJ -
Multiple HOM-C gene interactions specify cell fates in the nematode central nervous system.
Genes & development 1993 Salser SJ, Loer CM, Kenyon C -
A homeotic gene cluster patterns the anteroposterior body axis of C. elegans.
Cell 1993 Wang BB, Müller-Immergluck MM, Austin J, Robinson NT, Chisholm A, Kenyon C -
Two wnt genes in Caenorhabditis elegans.
Oncogene 1993 Shackleford GM, Shivakumar S, Shiue L, Mason J, Kenyon C, Varmus HE -
Cell signals allow the expression of a pre-existent neural pattern in C. elegans.
Development (Cambridge, England) 1992 Waring DA, Wrischnik L, Kenyon C -
Expression of the homeotic gene mab-5 during Caenorhabditis elegans embryogenesis.
Development (Cambridge, England) 1992 Cowing DW, Kenyon C -
Activation of a C. elegans Antennapedia homologue in migrating cells controls their direction of migration.
Nature 1992 Salser SJ, Kenyon C -
A cluster of Antennapedia-class homeobox genes in a nonsegmented animal.
Science (New York, N.Y.) 1991 Kenyon C, Wang B -
Regulation of cellular responsiveness to inductive signals in the developing C. elegans nervous system.
Nature 1991 Waring DA, Kenyon C -
Ras proteins. Some signal developments.
Nature 1990 Bourne HR, Wrischnik L, Kenyon C -
Selective silencing of cell communication influences anteroposterior pattern formation in C. elegans.
Cell 1990 Waring DA, Kenyon C -
Cellular dialogs during development.
Cell 1989 Kenyon C, Kamb A -
Identification of genes from pattern formation, tyrosine kinase, and potassium channel families by DNA amplification.
Proceedings of the National Academy of Sciences of the United States of America 1989 Kamb A, Weir M, Rudy B, Varmus H, Kenyon C -
Posterior pattern formation in C. elegans involves position-specific expression of a gene containing a homeobox.
Cell 1988 Costa M, Weir M, Coulson A, Sulston J, Kenyon C -
The nematode Caenorhabditis elegans.
Science (New York, N.Y.) 1988 Kenyon C -
A gene involved in the development of the posterior body region of C. elegans.
Cell 1986 Kenyon C