Claus Niemann, MD
Professor Emeritus
Anesthesia
School of Medicine

The goal of this research effort is to improve understanding of the impact of leptin on acute inflammatory cascade and metabolic response during hepatic ischemia-reperfusion. This will benefit patients by improving risk-stratification of candidates for hepatic surgery and possibly lead to preventive therapies for ischemia-reperfusion injury.

• Perioperative mortality in liver transplantation before and after the implementation of the organ allocation policy Share 35.
  Clinical transplantation 2022 Holm ZD, Kolodzie K, Galli AM, Meyhoff CS, Niemann CU, Adelmann D
• Advantages and Limitations of Clinical Scores for Donation After Circulatory Death Liver Transplantation.
  Frontiers in surgery 2022 Meier RPH, Kelly Y, Yamaguchi S, Braun HJ, Lunow-Luke T, Adelmann D, Niemann C, Maluf DG, Dietch ZC, Stock PG, Kang SM, Feng S, Posselt AM, Gardner JM, Syed SM, Hirose R, Freise CE, Ascher NL, Roberts…
• Expedited evaluation for liver transplantation: A critical look at processes and outcomes.
  Clinical transplantation 2021 Braun HJ, Mello A, Kothari R, Ku E, Yilma M, Tavakol M, Zhang L, Niemann CU, Ascher NL, Adelmann D
• Organ donor management goals and delayed graft function in adult kidney transplant recipients.
  Clinical transplantation 2021 Kothari R, Tolles J, Adelmann D, Lewis RJ, Malinoski DJ, Niemann CU
• Perioperative Normal Saline Administration and Delayed Graft Function in Patients Undergoing Kidney Transplantation: A Retrospective Cohort Study.
  Anesthesiology 2021 Kolodzie K, Cakmakkaya OS, Boparai ES, Tavakol M, Feiner JR, Kim MO, Newman TB, Niemann CU
• Machine Learning Prediction of Liver Allograft Utilization From Deceased Organ Donors Using the National Donor Management Goals Registry.
  Transplantation direct 2021 Bishara AM, Lituiev DS, Adelmann D, Kothari RP, Malinoski DJ, Nudel JD, Sally MB, Hirose R, Hadley DD, Niemann CU
• Enhanced recovery after surgery programs improve short-term outcomes after liver transplantation-A systematic review and meta-analysis.
  Clinical transplantation 2021 Tinguely P, Morare N, Ramirez-Del Val A, Berenguer M, Niemann CU, Pollok JM, Raptis DA, Spiro M
• Assessment of the global practice of living donor liver transplantation.
  Transplant international : official journal of the European Society for Organ Transplantation 2021 Emamaullee J, Conrad C, Kim M, Goldbeck C, Kwon Y, Singh P, Niemann CU, Sher L, Genyk Y
• Raster Thomson scattering in large-scale laser plasmas produced at high repetition rate.
  The Review of scientific instruments 2021 Kaloyan M, Ghazaryan S, Constantin CG, Dorst RS, Heuer PV, Pilgram JJ, Schaeffer DB, Niemann C
• Critical care and ventilatory management of deceased organ donors impact lung use and recipient graft survival.
  American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2021 Swanson EA, Patel MS, Hutchens MP, Niemann CU, Groat T, Malinoski DJ, Sally MB
• Shared B cell memory to coronaviruses and other pathogens varies in human age groups and tissues.
  Science (New York, N.Y.) 2021 Yang F, Nielsen SCA, Hoh RA, Röltgen K, Wirz OF, Haraguchi E, Jean GH, Lee JY, Pham TD, Jackson KJL, Roskin KM, Liu Y, Nguyen K, Ohgami RS, Osborne EM, Nadeau KC, Niemann CU, Parsonnet J, Boyd SD
• Prospective Multicenter Study of Early Antiviral Therapy in Liver and Kidney Transplant Recipients of HCV-Viremic Donors.
  Hepatology (Baltimore, Md.) 2021 Terrault NA, Burton J, Ghobrial M, Verna E, Bayer J, Klein C, Victor D, Mohan S, Trotter J, Dodge J, Niemann CU, Rubin RA
• Weighing the waitlist: Weight changes and access to kidney transplantation among obese candidates.
  PloS one 2020 Ku E, Whelan AM, McCulloch CE, Lee B, Niemann CU, Roll GR, Grimes BA, Johansen KL
• COVID-19 and Abdominal Transplant: A Stepwise Approach to Practice During Pandemic Conditions.
  Transplantation 2020 Syed SM, Gardner J, Roll G, Webber A, Mehta N, Shoji J, Adelmann D, Niemann C, Braun HJ, Mello A, Yao F, Posselt A, Kang SM, Hirose R, Roberts J, Feng S, Ascher N, Stock P, Freise C
• The Association Between Vena Cava Implantation Technique and Acute Kidney Injury After Liver Transplantation.
  Transplantation 2020 Hannon V, Kothari RP, Zhang L, Bokoch MP, Hill R, Roll GR, Mello A, Feiner JR, Liu KD, Niemann CU, Adelmann D
• Measurements of ion velocity distributions in a large scale laser-produced plasma.
  The Review of scientific instruments 2020 Dorst RS, Heuer PV, Schaeffer DB, Constantin CG, Niemann C
• Longer Distance From Dialysis Facility to Transplant Center Is Associated With Lower Access to Kidney Transplantation.
  Transplantation direct 2020 Whelan AM, Johansen KL, McCulloch CE, Adelmann D, Niemann CU, Roll GR, Siyahian S, Grimes B, Ku E
• Senolytics prevent mt-DNA-induced inflammation and promote the survival of aged organs following transplantation.
  Nature communications 2020 Iske J, Seyda M, Heinbokel T, Maenosono R, Minami K, Nian Y, Quante M, Falk CS, Azuma H, Martin F, Passos JF, Niemann CU, Tchkonia T, Kirkland JL, Elkhal A, Tullius SG
• Impact of Deceased Donor Management on Donor Heart Use and Recipient Graft Survival.
  Journal of the American College of Surgeons 2020 Swanson EA, Adams T, Patel MS, De La Cruz S, Hutchens M, Khush K, Sally MB, Niemann CU, Groat T, Malinoski DJ
• Bacchus Listed for a Liver Transplant: Comment.
  Anesthesiology 2020 Niemann CU
• Vasopressor selection during critical care management of brain dead organ donors and the effects on kidney graft function.
  The journal of trauma and acute care surgery 2020 Swanson EA, Patel MS, Groat T, Jameson NE, Ellis MKM, Hutchens MP, Niemann CU, Malinoski DJ, Sally MB
• The role of deceased donor liver biopsy: An analysis of 5449 liver transplant recipients.
  Clinical transplantation 2020 Patel MS, Mohebali J, Coe TM, Sally M, Groat T, Niemann CU, Malinoski DJ, Vagefi PA
• Transplant anesthesia and critical care: Current research and possible future developments.
  Best practice & research. Clinical anaesthesiology 2020 Niemann CU, Biancofiore G
• Therapeutic Hypothermia in Organ Donors: Follow-up and Safety Analysis.
  Transplantation 2019 Malinoski D, Patel MS, Axelrod DA, Broglio K, Lewis RJ, Groat T, Niemann CU
• Modeling the economic benefit of targeted mild hypothermia in deceased donor kidney transplantation.
  Clinical transplantation 2019 Axelrod DA, Malinoski D, Patel MS, Broglio K, Lewis R, Groat T, Lentine KL, Schnitzler M, Niemann CU
• The Continued Need for Clinical Trials in Deceased Organ Donor Management.
  Transplantation 2019 Niemann CU, Matthay MA, Ware LB
• Deceased organ donor factors influencing pancreatic graft transplantation and survival.
  Clinical transplantation 2019 Sally MB, Ellis MK, Hutchens M, Groat T, Swanson E, Patel MS, Niemann CU, Malinoski DJ
• The Impact of Deceased Donor Liver Extraction Time on Early Allograft Function in Adult Liver Transplant Recipients.
  Transplantation 2018 Adelmann D, Roll GR, Kothari R, Syed S, Burdine LJ, Tavakol M, Niemann CU
• Intraoperative Management of Liver Transplant Patients Without the Routine Use of Renal Replacement Therapy.
  Transplantation 2018 Adelmann D, Olmos A, Liu LL, Feiner JR, Roll GR, Burdine L, Tavakol M, Syed S, Orandi BJ, Niemann CU
• Central venous pressure monitoring in living donor kidney recipients does not affect immediate graft function: A propensity score analysis.
  Clinical transplantation 2018 Adelmann D, Bicknell L, Niemann CU, Feiner J, Roll GR, Burdine L, Whitlock EL
• Organ Donor Management: Part 1. Toward a Consensus to Guide Anesthesia Services During Donation After Brain Death.
  Seminars in cardiothoracic and vascular anesthesia 2017 Souter MJ, Eidbo E, Findlay JY, Lebovitz DJ, Moguilevitch M, Neidlinger NA, Wagener G, Paramesh AS, Niemann CU, Roberts PR, Pretto EA
• Comments on "Impact of spontaneous donor hypothermia on graft outcomes after kidney transplantation".
  American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2017 Niemann CU, Broglio K, Malinoski D
• Potentially inappropriate liver transplantation in the era of the "sickest first" policy - A search for the upper limits.
  Journal of hepatology 2017 Linecker M, Krones T, Berg T, Niemann CU, Steadman RH, Dutkowski P, Clavien PA, Busuttil RW, Truog RD, Petrowsky H
• Protecting the Kidney in Liver Transplant Recipients: Practice-Based Recommendations From the American Society of Transplantation Liver and Intestine Community of Practice.
  American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2016 Levitsky J, O'Leary JG, Asrani S, Sharma P, Fung J, Wiseman A, Niemann CU
• Therapeutic Hypothermia in Deceased Organ Donors and Kidney-Graft Function.
  The New England journal of medicine 2015 Niemann CU, Malinoski D
• Impact of a quality improvement project on deceased organ donor management.
  Progress in transplantation (Aliso Viejo, Calif.) 2015 Olmos A, Feiner J, Hirose R, Swain S, Blasi A, Roberts JP, Niemann CU
• Therapeutic Hypothermia in Deceased Organ Donors and Kidney-Graft Function.
  The New England journal of medicine 2015 Niemann CU, Feiner J, Swain S, Bunting S, Friedman M, Crutchfield M, Broglio K, Hirose R, Roberts JP, Malinoski D
• Management of the Potential Organ Donor in the ICU: Society of Critical Care Medicine/American College of Chest Physicians/Association of Organ Procurement Organizations Consensus Statement.
  Critical care medicine 2015 Kotloff RM, Blosser S, Fulda GJ, Malinoski D, Ahya VN, Angel L, Byrnes MC, DeVita MA, Grissom TE, Halpern SD, Nakagawa TA, Stock PG, Sudan DL, Wood KE, Anillo SJ, Bleck TP, Eidbo EE, Fowler RA, …
• The Impact of Hydroxyethyl Starch Use in Deceased Organ Donors on the Development of Delayed Graft Function in Kidney Transplant Recipients: A Propensity-Adjusted Analysis.
  American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2015 Patel MS, Niemann CU, Sally MB, De La Cruz S, Zatarain J, Ewing T, Crutchfield M, Enestvedt CK, Malinoski DJ
• A role for Rac1 activity in malignant progression of sebaceous skin tumors.
  Oncogene 2015 Frances D, Sharma N, Pofahl R, Maneck M, Behrendt K, Reuter K, Krieg T, Klein CA, Haase I, Niemann C
• Exercise-induced changes in basal ganglia volume and cognition in older adults.
  Neuroscience 2014 Niemann C, Godde B, Staudinger UM, Voelcker-Rehage C
• Abdominal transplantation.
  Anesthesiology clinics 2013 Niemann CU
• Patients with chronic kidney disease.
  The Medical clinics of North America 2013 Kalamas AG, Niemann CU
• Peri-operative hyperglycemia is associated with delayed graft function in deceased donor renal transplantation.
  Clinical transplantation 2013 Parekh J, Roll GR, Feng S, Niemann CU, Hirose R
• Functional elements associated with hepatic regeneration in living donors after right hepatic lobectomy.
  Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 2013 Everson GT, Hoefs JC, Niemann CU, Olthoff KM, Dupuis R, Lauriski S, Herman A, Milne N, Gillespie BW, Goodrich NP, Everhart JE
• Deceased organ donor research: the last research frontier?
  Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 2013 Mone T, Heldens J, Niemann CU
• Liver transplantation outcome in patients with angiographically proven coronary artery disease: a multi-institutional study.
  American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2012 Wray C, Scovotti JC, Tobis J, Niemann CU, Planinsic R, Walia A, Findlay J, Wagener G, Cywinski JB, Markovic D, Hughes C, Humar A, Olmos A, Sierra R, Busuttil R, Steadman RH
• Infrared pupillometry to detect the light reflex during cardiopulmonary resuscitation: a case series.
  Resuscitation 2012 Behrends M, Niemann CU, Larson MD
• Optimizing cost-effectiveness in perioperative care for liver transplantation: a model for low- to medium-income countries.
  Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 2011 Rando K, Niemann CU, Taura P, Klinck J
• Intraoperative hyperglycemia augments ischemia reperfusion injury in renal transplantation: a prospective study.
  Journal of transplantation 2011 Parekh J, Niemann CU, Dang K, Hirose R
• Transplant critical care: standards for intensive care of the patient with liver failure before and after transplantation.
  Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 2011 Niemann CU, Kramer DJ
• Intraoperative management of liver transplant patients.
  Transplantation reviews (Orlando, Fla.) 2011 Liu LL, Niemann CU
• Donor pre-treatment with everolimus or cyclosporine does not reduce ischaemia-reperfusion injury in a rat kidney transplant model.
  Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2010 Martinez-Palli G, Hirose R, Liu T, Xu F, Dang K, Feiner J, Serkova NJ, Niemann CU
• Multivessel coronary artery disease predicts mortality, length of stay, and pressor requirements after liver transplantation.
  Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 2010 Yong CM, Sharma M, Ochoa V, Abnousi F, Roberts J, Bass NM, Niemann CU, Shiboski S, Prasad M, Tavakol M, Ports TA, Gregoratos G, Yeghiazarians Y, Boyle AJ
• Liver transplant perioperative pathways: which way towards high-quality care and better outcomes?
  Minerva anestesiologica 2010 Biancofiore G, Niemann CU
• Mapping the ionization state of laser-irradiated Ar gas jets with multiwavelength monochromatic x-ray imaging.
  The Review of scientific instruments 2010 Kugland NL, Döppner T, Kemp A, Schaeffer D, Glenzer SH, Niemann C
• 1H-NMR-based metabolic signatures of clinical outcomes in trauma patients--beyond lactate and base deficit.
  The Journal of trauma 2010 Cohen MJ, Serkova NJ, Wiener-Kronish J, Pittet JF, Niemann CU
• Chronic kidney disease: implications for the perioperative period.
  Minerva anestesiologica 2010 Eilers H, Liu KD, Gruber A, Niemann CU
• Induction of intestinal ischemia reperfusion injury by portal vein outflow occlusion in rats.
  Journal of gastroenterology 2010 Vincenti M, Behrends M, Dang K, Park YH, Hirose R, Blasi-Ibanez A, Liu T, Serkova NJ, Niemann CU
• Quality improvement in transplant anesthesia: which way forward?
  Current opinion in organ transplantation 2010 Niemann CU, Feiner J
• Short passive cooling protects rats during hepatectomy by inducing heat shock proteins and limiting the induction of pro-inflammatory cytokines.
  The Journal of surgical research 2010 Niemann CU, Xu F, Choi S, Behrends M, Park Y, Hirose R, Maher JJ
• Evolution of elastic x-ray scattering in laser-shocked warm dense lithium.
  Physical review. E, Statistical, nonlinear, and soft matter physics 2009 Kugland NL, Gregori G, Bandyopadhyay S, Brenner CM, Brown CR, Constantin C, Glenzer SH, Khattak FY, Kritcher AL, Niemann C, Otten A, Pasley J, Pelka A, Roth M, Spindloe C, Riley D
• Acute hyperglycemia worsens hepatic ischemia/reperfusion injury in rats.
  Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 2009 Behrends M, Martinez-Palli G, Niemann CU, Cohen S, Ramachandran R, Hirose R
• Acute kidney injury during liver transplantation as determined by neutrophil gelatinase-associated lipocalin.
  Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 2009 Niemann CU, Walia A, Waldman J, Davio M, Roberts JP, Hirose R, Feiner J
• Abdominal organ transplantation.
  Minerva anestesiologica 2009 Niemann CU, Eilers H
• Systemic inflammation, coagulopathy, and acute renal insufficiency following endovascular thoracoabdominal aortic aneurysm repair.
  Journal of vascular surgery 2009 Chang CK, Chuter TA, Niemann CU, Shlipak MG, Cohen MJ, Reilly LM, Hiramoto JS
• Predictors associated with terminal renal function in deceased organ donors in the intensive care unit.
  Anesthesiology 2009 Blasi-Ibanez A, Hirose R, Feiner J, Freise C, Stock PG, Roberts JP, Niemann CU
• Postoperative infectious complications of abdominal solid organ transplantation.
  Journal of intensive care medicine 2008 Hlava N, Niemann CU, Gropper MA, Melcher ML
• High contrast Kr gas jet K alpha x-ray source for high energy density physics experiments.
  The Review of scientific instruments 2008 Kugland NL, Neumayer P, Döppner T, Chung HK, Constantin CG, Girard F, Glenzer SH, Kemp A, Niemann C
• Alterations in the proteome of pulmonary alveolar type II cells in the rat after hepatic ischemia-reperfusion.
  Critical care medicine 2008 Hirsch J, Niemann CU, Hansen KC, Choi S, Su X, Frank JA, Fang X, Hirose R, Theodore P, Sapru A, Burlingame AL, Matthay MA
• Perioperative liver transplant best practices: weighing the evidence.
  Current opinion in organ transplantation 2008 Mandell MS, Niemann CU
• Transient hyperglycemia affects the extent of ischemia-reperfusion-induced renal injury in rats.
  Anesthesiology 2008 Hirose R, Xu F, Dang K, Liu T, Behrends M, Brakeman PR, Wiener-Kronish J, Niemann CU
• Green frequency-doubled laser-beam propagation in high-temperature hohlraum plasmas.
  Physical review letters 2008 Niemann C, Berger RL, Divol L, Froula DH, Jones O, Kirkwood RK, Meezan N, Moody JD, Ross J, Sorce C, Suter LJ, Glenzer SH
• Increased severity of renal ischemia-reperfusion injury with venous clamping compared to arterial clamping in a rat model.
  Surgery 2007 Park Y, Hirose R, Dang K, Xu F, Behrends M, Tan V, Roberts JP, Niemann CU
• A multicenter evaluation of safety of early extubation in liver transplant recipients.
  Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 2007 Mandell MS, Stoner TJ, Barnett R, Shaked A, Bellamy M, Biancofiore G, Niemann C, Walia A, Vater Y, Tran ZV, Kam I
• Remote renal injury following partial hepatic ischemia/reperfusion injury in rats.
  Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 2007 Behrends M, Hirose R, Park YH, Tan V, Dang K, Xu F, Park SH, Niemann CU
• Biochemical mechanisms of nephrotoxicity: application for metabolomics.
  Expert opinion on drug metabolism & toxicology 2007 Niemann CU, Serkova NJ
• Early detection of graft failure using the blood metabolic profile of a liver recipient.
  Transplantation 2007 Serkova NJ, Zhang Y, Coatney JL, Hunter L, Wachs ME, Niemann CU, Mandell MS
• Glutamine donor pretreatment in rat kidney transplants with severe preservation reperfusion injury.
  The Journal of surgical research 2007 Fuller TF, Rose F, Singleton KD, Linde Y, Hoff U, Freise CE, Dragun D, Niemann CU
• Central venous pressure monitoring during living right donor hepatectomy.
  Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 2007 Niemann CU, Feiner J, Behrends M, Eilers H, Ascher NL, Roberts JP
• Ischemia-reperfusion injury is more severe in older versus young rat livers.
  The Journal of surgical research 2006 Park Y, Hirose R, Coatney JL, Ferrell L, Behrends M, Roberts JP, Serkova NJ, Niemann CU
• Pattern recognition and biomarker validation using quantitative 1H-NMR-based metabolomics.
  Expert review of molecular diagnostics 2006 Serkova NJ, Niemann CU
• Mild hypothermia reduces the inflammatory response and hepatic ischemia/reperfusion injury in rats.
  Liver international : official journal of the International Association for the Study of the Liver 2006 Behrends M, Hirose R, Serkova NJ, Coatney JL, Bedolli M, Yardi J, Park YH, Niemann CU
• Mild hypothermia protects obese rats from fulminant hepatic necrosis induced by ischemia-reperfusion.
  Surgery 2006 Niemann CU, Choi S, Behrends M, Hirose R, Noh J, Coatney JL, Roberts JP, Serkova NJ, Maher JJ
• Recombinant factor VIIa reduces transfusion requirements in liver transplant patients with high MELD scores.
  Transfusion medicine (Oxford, England) 2006 Niemann CU, Behrends M, Quan D, Eilers H, Gropper MA, Roberts JP, Hirose R
• Warm ischemia-induced alterations in oxidative and inflammatory proteins in hepatic Kupffer cells in rats.
  Molecular & cellular proteomics : MCP 2006 Hirsch J, Hansen KC, Choi S, Noh J, Hirose R, Roberts JP, Matthay MA, Burlingame AL, Maher JJ, Niemann CU
• Glutamine does not protect against hepatic warm ischemia/reperfusion injury in rats.
  Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 2006 Noh J, Behrends M, Choi S, Bedolli MA, Yardi J, Hirose R, Niemann CU
• Ischemic preconditioning improves energy state and transplantation survival in obese Zucker rat livers.
  Anesthesia and analgesia 2005 Niemann CU, Hirose R, Liu T, Behrends M, Brown JL, Kominsky DF, Roberts JP, Serkova N
• Metabolic profiling of livers and blood from obese Zucker rats.
  Journal of hepatology 2005 Serkova NJ, Jackman M, Brown JL, Liu T, Hirose R, Roberts JP, Maher JJ, Niemann CU
• H-NMR-based metabolic signatures of mild and severe ischemia/reperfusion injury in rat kidney transplants.
  Kidney international 2005 Serkova N, Fuller TF, Klawitter J, Freise CE, Niemann CU
• Mild hypothermia provides significant protection against ischemia/reperfusion injury in livers of obese and lean rats.
  Annals of surgery 2005 Choi S, Noh J, Hirose R, Ferell L, Bedolli M, Roberts JP, Niemann CU
• Ischemic preconditioning improves rat kidney graft function after severe ischemia/reperfusion injury.
  Transplantation proceedings 2005 Fuller TF, Freise CE, Feng S, Niemann CU
• Automated, fast, and sensitive quantification of drugs in human plasma by LC/LC-MS: quantification of 6 protease inhibitors and 3 nonnucleoside transcriptase inhibitors.
  Therapeutic drug monitoring 2004 Egge-Jacobsen W, Unger M, Niemann CU, Baluom M, Hirai S, Benet LZ, Christians U
• Beta-adrenergic blockade affects initial drug distribution due to decreased cardiac output and altered blood flow distribution.
  The Journal of pharmacology and experimental therapeutics 2004 Avram MJ, Krejcie TC, Henthorn TK, Niemann CU
• Intraoperative fluid management of living donor versus cadaveric liver transplant recipients.
  Transplantation proceedings 2004 Niemann CU, Hirose R, Stock P, Roberts JP, Mandell S, Spencer Yost C
• Influence of donor pretreatment with N-acetylcysteine on ischemia/reperfusion injury in rat kidney grafts.
  The Journal of urology 2004 Fuller TF, Serkova N, Niemann CU, Freise CE
• Sirolimus delays recovery of rat kidney transplants after ischemia-reperfusion injury.
  Transplantation 2003 Fuller TF, Freise CE, Serkova N, Niemann CU, Olson JL, Feng S
• Mechanism of pupillary reflex dilation in awake volunteers and in organ donors.
  Anesthesiology 2003 Yang LL, Niemann CU, Larson MD
• The effects of desflurane and propofol on portosystemic pressure in patients with portal hypertension.
  Anesthesia and analgesia 2003 Mandell MS, Durham J, Kumpe D, Trotter JF, Everson GT, Niemann CU
• Organ-specific response to inhibition of mitochondrial metabolism by cyclosporine in the rat.
  Transplant international : official journal of the European Society for Organ Transplantation 2003 Serkova N, Klawitter J, Niemann CU
• Clinically important drug interactions with intravenous anaesthetics in older patients.
  Drugs & aging 2003 Eilers H, Niemann C
• Intraoperative hemodynamics and liver function in adult-to-adult living liver donors.
  Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 2002 Niemann CU, Roberts JP, Ascher NL, Yost CS
• Elimination of indocyanine green in the perioperative evaluation of donor liver function.
  Anesthesia and analgesia 2002 Mandell MS, Wachs M, Niemann CU, Henthorn TK
• Cyclosporine can increase isoflurane MAC.
  Anesthesia and analgesia 2002 Niemann CU, Stabernack C, Serkova N, Jacobsen W, Christians U, Eger EI
• Close association between the reduction in myocardial energy metabolism and infarct size: dose-response assessment of cyclosporine.
  The Journal of pharmacology and experimental therapeutics 2002 Niemann CU, Saeed M, Akbari H, Jacobsen W, Benet LZ, Christians U, Serkova N
• Evaluation of the splanchnic circulation with indocyanine green pharmacokinetics in liver transplant patients.
  Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 2002 Niemann CU, Yost CS, Mandell S, Henthorn TK
• Comparison of the effects of cyclosporin a on the metabolism of perfused rat brain slices during normoxia and hypoxia.
  Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2002 Serkova N, Donohoe P, Gottschalk S, Hainz C, Niemann CU, Bickler PE, Litt L, Benet LZ, Leibfritz D, Christians U
• Sirolimus, but not the structurally related RAD (everolimus), enhances the negative effects of cyclosporine on mitochondrial metabolism in the rat brain.
  British journal of pharmacology 2001 Serkova N, Jacobsen W, Niemann CU, Litt L, Benet LZ, Leibfritz D, Christians U
• Isoflurane alters the recirculatory pharmacokinetics of physiologic markers.
  Anesthesiology 2000 Avram MJ, Krejcie TC, Niemann CU, Enders-Klein C, Shanks CA, Henthorn TK
• Indocyanine green kinetics characterize blood volume and flow distribution and their alteration by propranolol.
  Clinical pharmacology and therapeutics 2000 Niemann CU, Henthorn TK, Krejcie TC, Shanks CA, Enders-Klein C, Avram MJ
• Ketamine distribution described by a recirculatory pharmacokinetic model is not stereoselective.
  Anesthesiology 1999 Henthorn TK, Krejcie TC, Niemann CU, Enders-Klein C, Shanks CA, Avram MJ
• Modifications of blood volume alter the disposition of markers of blood volume, extracellular fluid, and total body water.
  The Journal of pharmacology and experimental therapeutics 1999 Krejcie TC, Henthorn TK, Gentry WB, Niemann CU, Enders-Klein C, Shanks CA, Avram MJ
• The effect of halothane on the recirculatory pharmacokinetics of physiologic markers.
  Anesthesiology 1997 Avram MJ, Krejcie TC, Niemann CU, Klein C, Gentry WB, Shanks CA, Henthorn TK
• A recirculatory model of the pulmonary uptake and pharmacokinetics of lidocaine based on analysis of arterial and mixed venous data from dogs.
  Journal of pharmacokinetics and biopharmaceutics 1997 Krejcie TC, Avram MJ, Gentry WB, Niemann CU, Janowski MP, Henthorn TK
• Use of parallel Erlang density functions to analyze first-pass pulmonary uptake of multiple indicators in dogs.
  Journal of pharmacokinetics and biopharmaceutics 1996 Krejcie TC, Jacquez JA, Avram MJ, Niemann CU, Shanks CA, Henthorn TK
• Recirculatory pharmacokinetic models of markers of blood, extracellular fluid and total body water administered concomitantly.
  The Journal of pharmacology and experimental therapeutics 1996 Krejcie TC, Henthorn TK, Niemann CU, Klein C, Gupta DK, Gentry WB, Shanks CA, Avram MJ