Claire Clelland, MD, PhD
Assistant Professor
Neurology
School of Medicine

Awards

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• Outstanding Mentoring Award, Gladstone Institues, 2022
• School of Medicine Dean’s Commendation for Exceptional Volunteerism and Community Service for, UCSF, 2021
• Weill Award for Clinician-Scientists in the Neurosciences, UCSF, 2021
• Marshall's Scholarship, UK Marshall Aid Commemoration Commission, British Parliament, 2006-2008
• Jack Kent Cooke Graduate Fellowship, Jack Kent Cooke Foundation, 2005-2013

Education & Training

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• Diversity, Equity, and Inclusion Champion Training University of California 2021
• Neurology Residency University of California, San Francisco 06/2017
• Medicine Internship University of California, San Francisco 06/2014
• M.D. Medicine University of California, Los Angeles 05/2013
• Ph.D. Neuroscience University of California, San Diego 08/2009
• M.Phil. Neuroscience University of Cambridge 07/2009

Websites

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• Clelland lab (clellandlab.ucsf.edu)

Publications (13)

Top publication keywords:
Dentate GyrusDiffusion Tensor ImagingCluster HeadacheDeep Brain StimulationCraniocerebral TraumaDiscrimination LearningHypothalamusAmyotrophic Lateral SclerosisHuntington DiseaseFrontotemporal DementiaCell- and Tissue-Based TherapyConnectomeClustered Regularly Interspaced Short Palindromic RepeatsCRISPR-Cas SystemsMicroglia

• Building CRISPR Gene Therapies for the Central Nervous System: A Review.
  JAMA neurology 2024 Salomonsson SE, Clelland CD
• Validated assays for the quantification of C9orf72 human pathology.
  Scientific reports 2024 Salomonsson SE, Maltos AM, Gill K, Aladesuyi Arogundade O, Brown KA, Sachdev A, Sckaff M, Lam KJK, Fisher IJ, Chouhan RS, Van Laar VS, Marley CB, McLaughlin I, Bankiewicz KS, Tsai YC, Conklin BR, …
• Novel avenues of tau research.
  Alzheimer's & dementia : the journal of the Alzheimer's Association 2024 Sexton CE, Bitan G, Bowles KR, Brys M, Buée L, Maina MB, Clelland CD, Cohen AD, Crary JF, Dage JL, Diaz K, Frost B, Gan L, Goate AM, Golbe LI, Hansson O, Karch CM, Kolb HC, La Joie R, Lee SE, …
• Functional characterization of Alzheimer's disease genetic variants in microglia.
  Nature genetics 2023 Yang X, Wen J, Yang H, Jones IR, Zhu X, Liu W, Li B, Clelland CD, Luo W, Wong MY, Ren X, Cui X, Song M, Liu H, Chen C, Eng N, Ravichandran M, Sun Y, Lee D, Van Buren E, Jiang MZ, Chan CSY, Ye CJ, …
• A CRISPRi/a platform in human iPSC-derived microglia uncovers regulators of disease states.
  Nature neuroscience 2022 Dräger NM, Sattler SM, Huang CT, Teter OM, Leng K, Hashemi SH, Hong J, Aviles G, Clelland CD, Zhan L, Udeochu JC, Kodama L, Singleton AB, Nalls MA, Ichida J, Ward ME, Faghri F, Gan L, Kampmann M

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• Astrocyte-derived extracellular vesicles enhance the survival and electrophysiological function of human cortical neurons in vitro.
  Biomaterials 2021 Chun C, Smith AST, Kim H, Kamenz DS, Lee JH, Lee JB, Mack DL, Bothwell M, Clelland CD, Kim DH
• Microglial microRNAs mediate sex-specific responses to tau pathology.
  Nature neuroscience 2019 Kodama L, Guzman E, Etchegaray JI, Li Y, Sayed FA, Zhou L, Zhou Y, Zhan L, Le D, Udeochu JC, Clelland CD, Cheng Z, Yu G, Li Q, Kosik KS, Gan L
• Differential effects of partial and complete loss of TREM2 on microglial injury response and tauopathy.
  Proceedings of the National Academy of Sciences of the United States of America 2018 Sayed FA, Telpoukhovskaia M, Kodama L, Li Y, Zhou Y, Le D, Hauduc A, Ludwig C, Gao F, Clelland C, Zhan L, Cooper YA, Davalos D, Akassoglou K, Coppola G, Gan L
• Dopaminergic manipulations and its effects on neurogenesis and motor function in a transgenic mouse model of Huntington's disease.
  Neurobiology of disease 2014 Choi ML, Begeti F, Oh JH, Lee SY, O'Keeffe GC, Clelland CD, Tyers P, Cho ZH, Kim YB, Barker RA
• Common cerebral networks associated with distinct deep brain stimulation targets for cluster headache.
  Cephalalgia : an international journal of headache 2013 Clelland CD, Zheng Z, Kim W, Bari A, Pouratian N
• Comprehensive review of stereotactic radiosurgery for medically and surgically refractory pituitary adenomas.
  Surgical neurology international 2012 Kim W, Clelland C, Yang I, Pouratian N
• A functional role for adult hippocampal neurogenesis in spatial pattern separation.
  Science (New York, N.Y.) 2009 Clelland CD, Choi M, Romberg C, Clemenson GD, Fragniere A, Tyers P, Jessberger S, Saksida LM, Barker RA, Gage FH, Bussey TJ
• Cell therapy in Huntington disease.
  Neurosurgical focus 2008 Clelland CD, Barker RA, Watts C