Chuck Rickert, MD, PhD
Assistant Professor
Surgery
School of Medicine

Since 2014, I have been a general surgery resident at the Massachusetts General Hospital, in Boston, MA. In addition to working in all areas of general surgery, I have been particularly engaged in efforts to connect to the community and decrease the impact of prejudice and bias in the care for surgery patients. SERVICE ACTIVITIES SUMMARY In my residency at the Massachusetts General Hospital, I have participated in numerous activities for the community and the institution, including teaching medical students and resident, and performing community outreach. Contributions to Diversity, Equity & Inclusion Guidance Organized and led programming in implicit bias and publishing on the findings of our surgery department at Massachusetts General Hospital TEACHING SUMMARY Informal Teaching as a Resident in General Surgery, awarded the MGH Resident Teaching Award from the Harvard Medical School RESEARCH AND CREATIVE ACTIVITIES SUMMARY Primary research focus is on transplant immunology and the development of sustainable xenotransplantation systems. These efforts include fundamental research into the role of various immune regulatory cells, include regulatory T cells and B cells, in the development of allograft tolerance and large animal studies to understand the impact of genetic modifications on the survival of kidney and liver porcine allografts. Beyond basic science research, I also do research on the equitably distribution of transplant allografts, specifically liver allocation, as well as disparities in healthcare and bias.

• Surgeon crossover between pediatric and adult centers is associated with decreased rate of loss to follow-up among adolescent renal transplantation recipients.
  Pediatric transplantation 2019 Hung YC, Williams JE, Bababekov YJ, Rickert CG, Chang DC, Yeh H
• Health Literacy Burden Is Associated With Access to Liver Transplantation.
  Transplantation 2019 Bababekov YJ, Hung YC, Rickert CG, Njoku FC, Cao B, Adler JT, Brega AG, Pomposelli JJ, Chang DC, Yeh H
• Transplantation, Bioengineering, and Regeneration of the Endocrine Pancreas
  Progress Toward Islet Transplantation Tolerance 2019 Markmann, J.F. Rickert, C. G.
• Handbook of Immunosenescence: Basic Understanding and Clinical Applications
  Aging, Immunosenescence, and Transplantation Tolerance 2018 Rickert, C.G. Markmann, J.F.
• A surprising cross-species conservation in the genomic landscape of mouse and human oral cancer identifies a transcriptional signature predicting metastatic disease.
  Clinical cancer research : an official journal of the American Association for Cancer Research 2014 Onken MD, Winkler AE, Kanchi KL, Chalivendra V, Law JH, Rickert CG, Kallogjeri D, Judd NP, Dunn GP, Piccirillo JF, Lewis JS, Mardis ER, Uppaluri R
• Dysregulated STAT1-SOCS1 control of JAK2 promotes mammary luminal progenitor cell survival and drives ER+ tumorigenesis
  Cell Death and Differentiation 2014 Chan, S. R. Rickert, C. G. Vermi, W. Sheehan, K. C. F. Arthur, C. Allen, J. A. White, J. M. Archambault, J. Lonardi, S. McDevitt, T. M. Bhattacharya, D. Lorenzi, M. V. Allred, D. C. Schreiber, R. D.
• Cancer exome analysis reveals a T-cell-dependent mechanism of cancer immunoediting.
  Nature 2012 Matsushita H, Vesely MD, Koboldt DC, Rickert CG, Uppaluri R, Magrini VJ, Arthur CD, White JM, Chen YS, Shea LK, Hundal J, Wendl MC, Demeter R, Wylie T, Allison JP, Smyth MJ, Old LJ, Mardis ER, …
• STAT1-deficient mice spontaneously develop estrogen receptor α-positive luminal mammary carcinomas.
  Breast cancer research : BCR 2012 Chan SR, Vermi W, Luo J, Lucini L, Rickert C, Fowler AM, Lonardi S, Arthur C, Young LJ, Levy DE, Welch MJ, Cardiff RD, Schreiber RD
• Endoscopic surgical management of vidian nerve schwannoma.
  The Laryngoscope 2011 Hackman T, Rickert CG, Getz AE, Uppaluri R