Christine Miller, MD, PhD
RESIDENT
Pathology
School of Medicine

Education & Training

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• M.D., Ph.D. Immunology University of Chicago 06/2023
• B.S. Biomedical Engineering Columbia University, Fu Foundation School of Engineering and Applied Science 05/2013

Publications (10)

Top publication keywords:
Cell DifferentiationOsteoclastsOsteogenesisLymphopoiesisCD8-Positive T-LymphocytesReceptors, Antigen, T-CellThymus GlandBone ResorptionClonal Selection, Antigen-MediatedImmunoglobulin J Recombination Signal Sequence-Binding ProteinClone CellsTumor Necrosis Factor-alphaT-Lymphocytes, RegulatoryT-Box Domain ProteinsLymphocyte Activation

• The endogenous repertoire harbors self-reactive CD4+ T cell clones that adopt a follicular helper T cell-like phenotype at steady state.
  Nature immunology 2023 Lee V, Rodriguez DM, Ganci NK, Zeng S, Ai J, Chao JL, Walker MT, Miller CH, Klawon DEJ, Schoenbach MH, Kennedy DE, Maienschein-Cline M, Socci ND, Clark MR, Savage PA
• A local regulatory T cell feedback circuit maintains immune homeostasis by pruning self-activated T cells.
  Cell 2021 Wong HS, Park K, Gola A, Baptista AP, Miller CH, Deep D, Lou M, Boyd LF, Rudensky AY, Savage PA, Altan-Bonnet G, Tsang JS, Germain RN
• Altered selection on a single self-ligand promotes susceptibility to organ-specific T cell infiltration.
  The Journal of experimental medicine 2021 Klawon DEJ, Gilmore DC, Leonard JD, Miller CH, Chao JL, Walker MT, Duncombe RK, Tung KS, Adams EJ, Savage PA
• Eomes identifies thymic precursors of self-specific memory-phenotype CD8+ T cells.
  Nature immunology 2020 Miller CH, Klawon DEJ, Zeng S, Lee V, Socci ND, Savage PA
• Regulatory T Cell Development.
  Annual review of immunology 2020 Savage PA, Klawon DEJ, Miller CH

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• Def6 Restrains Osteoclastogenesis and Inflammatory Bone Resorption.
  Journal of immunology (Baltimore, Md. : 1950) 2017 Binder N, Miller C, Yoshida M, Inoue K, Nakano S, Hu X, Ivashkiv LB, Schett G, Pernis A, Goldring SR, Ross FP, Zhao B
• RBP-J-Regulated miR-182 Promotes TNF-α-Induced Osteoclastogenesis.
  Journal of immunology (Baltimore, Md. : 1950) 2016 Miller CH, Smith SM, Elguindy M, Zhang T, Xiang JZ, Hu X, Ivashkiv LB, Zhao B
• RBP-J imposes a requirement for ITAM-mediated costimulation of osteoclastogenesis.
  The Journal of clinical investigation 2014 Li S, Miller CH, Giannopoulou E, Hu X, Ivashkiv LB, Zhao B
• Morphological differences of primary cilia between human induced pluripotent stem cells and their parental somatic cells.
  Stem cells and development 2013 Nathwani BB, Miller CH, Yang TL, Solimano JL, Liao JC
• Superresolution STED microscopy reveals differential localization in primary cilia.
  Cytoskeleton (Hoboken, N.J.) 2012 Yang TT, Hampilos PJ, Nathwani B, Miller CH, Sutaria ND, Liao JC