Christine McDonald, ScD, MS
Associate Professor
Pediatrics
School of Medicine

Education & Training

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• Postdoctoral fellowship Global nutrition Boston Children's Hospital 10/2014
• ScD Nutritional Epidemiology Harvard TH Chan School of Public Health 05/2012
• MSc Food Policy and Applied Nutrition Tufts University Friedman School of Nutrition Science and Policy 05/2007
• BSc Food, Nutrition, and Health (Clinical Dietetics) University of British Columbia 04/2004

Publications (56)

Top publication keywords:
FlourFood, FortifiedMicronutrientsFolic Acid DeficiencyNutritional StatusTanzaniaLaboratoriesZincDietary SupplementsMalnutritionDiarrheaWasting SyndromeGrowth DisordersTrace ElementsFlagellin

• Women in Selected Communities of Punjab, India Have a High Prevalence of Iron, Zinc, Vitamin B12, and Folate Deficiencies: Implications for a Multiply-Fortified Salt Intervention.
  Nutrients 2023 Goh YE, Manger MS, Duggal M, Das R, Saklani S, Agarwal S, Budhija D, Jamwal M, Singh BL, Dahiya N, Luo H, Long JM, Westcott J, Krebs NF, Gibson RS, Brown KH, McDonald CM
• Estimating the cost and cost-effectiveness of adding zinc to, and improving the performance of, Burkina Faso's mandatory wheat flour fortification programme.
  Maternal & child nutrition 2023 Adams KP, Jarvis M, Vosti SA, Manger MS, Tarini A, Somé JW, Somda H, McDonald CM
• Anthropometric criteria for best-identifying children at high risk of mortality: a pooled analysis of twelve cohorts.
  Public health nutrition 2023 Khara T, Myatt M, Sadler K, Bahwere P, Berkley JA, Black RE, Boyd E, Garenne M, Isanaka S, Lelijveld N, McDonald C, Mertens A, Mwangome M, O'Brien K, Stobaugh H, Taneja S, West KP, Briend A
• Prognostic value of different anthropometric indices over different measurement intervals to predict mortality in 6-59-month-old children.
  Public health nutrition 2023 Briend A, Myatt M, Berkley JA, Black RE, Boyd E, Garenne M, Lelijveld N, Isanaka S, McDonald CM, Mwangwome M, O'Brien KS, Schwinger C, Stobaugh H, Taneja S, West KP, Khara T
• Effects of Different Doses, Forms, and Frequencies of Zinc Supplementation on Biomarkers of Iron and Zinc Status among Young Children in Dhaka, Bangladesh.
  Nutrients 2022 Islam MM, Black RE, Krebs NF, Westcott J, Long JM, Islam KM, Peerson JM, Sthity RA, Khandaker AM, Hasan M, El Arifeen S, Ahmed T, King JC, McDonald CM

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• Reply to R Pullakhandam et al.
  The Journal of nutrition 2022 McDonald CM, Black RE, Krebs NF, Islam MM
• Anthropometric deficits and the associated risk of death by age and sex in children aged 6-59 months: A meta-analysis.
  Maternal & child nutrition 2022 Thurstans S, Wrottesley SV, Fenn B, Khara T, Bahwere P, Berkley JA, Black RE, Boyd E, Garenne M, Isanaka S, Lelijveld N, McDonald CM, Mertens A, Mwangome M, O'Brien KS, Stobaugh H, Taneja S, West KP, …
• Quintuply-fortified salt for the improvement of micronutrient status among women of reproductive age and preschool-aged children in Punjab, India: protocol for a randomized, controlled, community-based trial.
  BMC nutrition 2022 McDonald CM, Brown KH, Goh YE, Manger MS, Arnold CD, Krebs NF, Westcott J, Long JM, Gibson RS, Jamwal M, Singh BL, Dahiya N, Budhija D, Das R, Duggal M
• Zinc Kinetics Correlate With Length-for-Age z Scores in Bangladeshi Infants.
  Journal of pediatric gastroenterology and nutrition 2022 Wastney ME, Long JM, McDonald CM, Krebs NF, Islam MM, Ahmed T, Khandaker AM, Sthity RA, Westcott JE, King JC
• Sex differences and associations between zinc deficiency and anemia among hospitalized adolescents and young adults with eating disorders.
  Eating and weight disorders : EWD 2022 Nagata JM, Bojorquez-Ramirez P, Nguyen A, Ganson KT, McDonald CM, Machen VI, Downey A, Buckelew SM, Garber AK
• Barriers to and Enablers of the Inclusion of Micronutrient Biomarkers in National Surveys and Surveillance Systems in Low- and Middle-Income Countries.
  Nutrients 2022 Manger MS, Brown KH, Osendarp SJM, Atkin RA, McDonald CM
• Correspondence on article by Pullakhandam et al. Reference cut-offs to define low serum zinc concentrations in healthy 1-19-year-old Indian children and adolescents.
  European journal of clinical nutrition 2022 McDonald CM, Manger MS, Krebs NF
• Different Doses, Forms, and Frequencies of Zinc Supplementation for the Prevention of Diarrhea and Promotion of Linear Growth among Young Bangladeshi Children: A Six-Arm, Randomized, Community-Based Efficacy Trial.
  The Journal of nutrition 2022 Islam MM, Black RE, Krebs NF, Westcott J, Long J, Islam KM, Peerson JM, Sthity RA, Khandaker AM, Hasan M, El Arifeen S, Ahmed T, King JC, McDonald CM
• Reconsidering the Tolerable Upper Levels of Zinc Intake among Infants and Young Children: A Systematic Review of the Available Evidence.
  Nutrients 2022 Wuehler S, Lopez de Romaña D, Haile D, McDonald CM, Brown KH
• Marginal Zinc Deficiency Alters Essential Fatty Acid Metabolism in Healthy Men.
  The Journal of nutrition 2022 Suh JH, Zyba SJ, Shigenaga M, McDonald CM, King JC
• The Role of Multiply-Fortified Table Salt and Bouillon in Food Systems Transformation.
  Nutrients 2022 Matthias D, McDonald CM, Archer N, Engle-Stone R
• Applying Zinc Nutrient Reference Values as Proposed by Different Authorities Results in Large Differences in the Estimated Prevalence of Inadequate Zinc Intake by Young Children and Women and in Cameroon.
  Nutrients 2022 Haile D, Brown KH, McDonald CM, Luo H, Jarvis M, Teta I, Ndjebayi A, Martial GAJ, Vosti SA, Engle-Stone R
• Exchangeable Zinc Pool Size Reflects Form of Zinc Supplementation in Young Children and Is Not Associated with Markers of Inflammation.
  Nutrients 2022 Long JM, Khandaker AM, Sthity RA, Westcott JE, Matveev A, Black RE, King JC, Islam KM, El Arifeen S, Ahmed T, Islam MM, McDonald CM, Krebs NF
• Zinc Supplementation with or without Additional Micronutrients Does Not Affect Peripheral Blood Gene Expression or Serum Cytokine Level in Bangladeshi Children.
  Nutrients 2021 Hayman T, Hickey P, Amann-Zalcenstein D, Bennett C, Ataide R, Sthity RA, Khandaker AM, Islam KM, Stracke K, Yassi N, Watson R, Long J, Westcott J, Krebs NF, King JC, Black RE, Islam MM, McDonald CM, …
• Effects of Foods Fortified with Zinc, Alone or Cofortified with Multiple Micronutrients, on Health and Functional Outcomes: A Systematic Review and Meta-Analysis.
  Advances in nutrition (Bethesda, Md.) 2021 Tsang BL, Holsted E, McDonald CM, Brown KH, Black R, Mbuya MNN, Grant F, Rowe LA, Manger MS
• Increasing the availability and utilization of reliable data on population micronutrient (MN) status globally: the MN Data Generation Initiative.
  The American journal of clinical nutrition 2021 Brown KH, Moore SE, Hess SY, McDonald CM, Jones KS, Meadows SR, Manger MS, Coates J, Alayon S, Osendarp SJM
• Comparison of Serum, Plasma, and Liver Zinc Measurements by AAS, ICP-OES, and ICP-MS in Diverse Laboratory Settings.
  Biological trace element research 2021 Hall AG, King JC, McDonald CM
• Testing metal, proving mettle-findings from the 2016-2018 India Comprehensive National Nutrition Survey regarding the prevalence of low serum zinc concentrations among children and adolescents, and their implications for public health.
  The American journal of clinical nutrition 2021 Brown KH, McDonald CM, Wessells KR, Hess SY
• Zinc-Biofortified Wheat Intake and Zinc Status Biomarkers in Men: Randomized Controlled Trial.
  The Journal of nutrition 2021 Liong EM, McDonald CM, Suh J, Westcott JL, Wong CP, Signorell C, King JC
• Enablers and Barriers of Zinc Fortification; Experience from 10 Low- and Middle-Income Countries with Mandatory Large-Scale Food Fortification.
  Nutrients 2021 Tarini A, Manger MS, Brown KH, Mbuya MNN, Rowe LA, Grant F, Black RE, McDonald CM
• Associations between Zinc and Hemoglobin Concentrations in Preschool Children and Women of Reproductive Age: An Analysis of Representative Survey Data from the Biomarkers Reflecting Inflammation and Nutritional Determinants of Anemia (BRINDA) Project.
  The Journal of nutrition 2021 Greffeuille V, Fortin S, Gibson R, Rohner F, Williams A, Young MF, Houghton L, Ou J, Dijkhuizen MA, Wirth JP, Lander RL, McDonald CM, Suchdev PS, Berger J, Wieringa FT
• Adjusting plasma or serum zinc concentrations for inflammation: Biomarkers Reflecting Inflammation and Nutritional Determinants of Anemia (BRINDA) project.
  The American journal of clinical nutrition 2020 McDonald CM, Suchdev PS, Krebs NF, Hess SY, Wessells KR, Ismaily S, Rahman S, Wieringa FT, Williams AM, Brown KH, King JC
• Reply to C Fabiansen et al.
  The Journal of nutrition 2019 McDonald CM, Ackatia-Armah RS, Doumbia S, Brown KH
• Setting research priorities on multiple micronutrient supplementation in pregnancy.
  Annals of the New York Academy of Sciences 2019 Gomes F, Bourassa MW, Adu-Afarwuah S, Ajello C, Bhutta ZA, Black R, Catarino E, Chowdhury R, Dalmiya N, Dwarkanath P, Engle-Stone R, Gernand AD, Goudet S, Hoddinott J, Kaestel P, Manger MS, McDonald …
• Early life risk factors of motor, cognitive and language development: a pooled analysis of studies from low/middle-income countries.
  BMJ open 2019 Sania A, Sudfeld CR, Danaei G, Fink G, McCoy DC, Zhu Z, Fawzi MCS, Akman M, Arifeen SE, Barros AJD, Bellinger D, Black MM, Bogale A, Braun JM, van den Broek N, Carrara V, Duazo P, Duggan C, Fernald …
• Percent Fat Mass Increases with Recovery, But Does Not Vary According to Dietary Therapy in Young Malian Children Treated for Moderate Acute Malnutrition.
  The Journal of nutrition 2019 McDonald CM, Ackatia-Armah RS, Doumbia S, Kupka R, Duggan CP, Brown KH
• Cost-effectiveness of community-based screening and treatment of moderate acute malnutrition in Mali.
  BMJ global health 2019 Isanaka S, Barnhart DA, McDonald CM, Ackatia-Armah RS, Kupka R, Doumbia S, Brown KH, Menzies NA
• Markers of Systemic Inflammation and Environmental Enteric Dysfunction Are Not Reduced by Zinc or Multivitamins in Tanzanian Infants: A Randomized, Placebo-Controlled Trial.
  The Journal of pediatrics 2019 Lauer JM, McDonald CM, Kisenge R, Aboud S, Fawzi WW, Liu E, Tran HQ, Gewirtz AT, Manji KP, Duggan CP
• Nutritional, Socioeconomic, and Delivery Characteristics Are Associated with Neurodevelopment in Tanzanian Children.
  The Journal of pediatrics 2018 Blakstad MM, Smith ER, Etheredge A, Locks LM, McDonald CM, Kupka R, Kisenge R, Aboud S, Bellinger D, Sudfeld CR, Fawzi WW, Manji K, Duggan CP
• From evidence to national scale: An implementation framework for micronutrient powders in Rwanda.
  Maternal & child nutrition 2018 McLean J, Northrup-Lyons M, Reid RJ, Smith L, Ho K, Mucumbitsi A, Kayumba J, Omwega A, McDonald C, Schauer C, Zlotkin S
• Biomarkers of Systemic Inflammation and Growth in Early Infancy are Associated with Stunting in Young Tanzanian Children.
  Nutrients 2018 Syed S, Manji KP, McDonald CM, Kisenge R, Aboud S, Sudfeld C, Locks L, Liu E, Fawzi WW, Duggan CP
• Markers of Environmental Enteric Dysfunction Are Associated With Neurodevelopmental Outcomes in Tanzanian Children.
  Journal of pediatric gastroenterology and nutrition 2018 Etheredge AJ, Manji K, Kellogg M, Tran H, Liu E, McDonald CM, Kisenge R, Aboud S, Fawzi W, Bellinger D, Gewirtz AT, Duggan CP
• A dynamic model for predicting growth in zinc-deficient stunted infants given supplemental zinc.
  The American journal of clinical nutrition 2018 Wastney ME, McDonald CM, King JC
• Study Protocol for a Randomized, Double-Blind, Community-Based Efficacy Trial of Various Doses of Zinc in Micronutrient Powders or Tablets in Young Bangladeshi Children.
  Nutrients 2018 Islam MM, McDonald CM, Krebs NF, Westcott J, Rahman AE, El Arifeen S, Ahmed T, King JC, Black RE
• Delayed Breastfeeding Initiation Is Associated with Infant Morbidity.
  The Journal of pediatrics 2017 Smith ER, Locks LM, Manji KP, McDonald CM, Kupka R, Kisenge R, Aboud S, Fawzi WW, Duggan CP
• Infant Nutritional Status and Markers of Environmental Enteric Dysfunction are Associated with Midchildhood Anthropometry and Blood Pressure in Tanzania.
  The Journal of pediatrics 2017 Locks LM, Mwiru RS, Mtisi E, Manji KP, McDonald CM, Liu E, Kupka R, Kisenge R, Aboud S, Gosselin K, Gillman M, Gewirtz AT, Fawzi WW, Duggan CP
• Etiology of Diarrhea, Nutritional Outcomes, and Novel Intestinal Biomarkers in Tanzanian Infants.
  Journal of pediatric gastroenterology and nutrition 2017 Gosselin KB, Aboud S, McDonald CM, Moyo S, Khavari N, Manji K, Kisenge R, Fawzi W, Kellogg M, Tran HQ, Kibiki G, Gratz J, Liu J, Gewirtz A, Houpt E, Duggan C
• High Burden of Morbidity and Mortality but Not Growth Failure in Infants Exposed to but Uninfected with Human Immunodeficiency Virus in Tanzania.
  The Journal of pediatrics 2016 Locks LM, Manji KP, Kupka R, Liu E, Kisenge R, McDonald CM, Aboud S, Wang M, Fawzi WW, Duggan CP
• The effect of daily zinc and/or multivitamin supplements on early childhood development in Tanzania: results from a randomized controlled trial.
  Maternal & child nutrition 2016 Locks LM, Manji KP, McDonald CM, Kupka R, Kisenge R, Aboud S, Wang M, Bellinger DC, Fawzi WW, Duggan CP
• Estimating the cost of delivering direct nutrition interventions at scale: national and subnational level insights from India.
  Maternal & child nutrition 2016 Menon P, McDonald CM, Chakrabarti S
• Elevations in serum anti-flagellin and anti-LPS Igs are related to growth faltering in young Tanzanian children.
  The American journal of clinical nutrition 2016 McDonald CM, Manji KP, Gosselin K, Tran H, Liu E, Kisenge R, Aboud S, Fawzi WW, Gewirtz AT, Duggan CP
• Effect of zinc and multivitamin supplementation on the growth of Tanzanian children aged 6-84 wk: a randomized, placebo-controlled, double-blind trial.
  The American journal of clinical nutrition 2016 Locks LM, Manji KP, McDonald CM, Kupka R, Kisenge R, Aboud S, Wang M, Fawzi WW, Duggan CP
• Daily Zinc but Not Multivitamin Supplementation Reduces Diarrhea and Upper Respiratory Infections in Tanzanian Infants: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial.
  The Journal of nutrition 2015 McDonald CM, Manji KP, Kisenge R, Aboud S, Spiegelman D, Fawzi WW, Duggan CP
• Malian children with moderate acute malnutrition who are treated with lipid-based dietary supplements have greater weight gains and recovery rates than those treated with locally produced cereal-legume products: a community-based, cluster-randomized trial.
  The American journal of clinical nutrition 2015 Ackatia-Armah RS, McDonald CM, Doumbia S, Erhardt JG, Hamer DH, Brown KH
• Correlates of household food insecurity and low dietary diversity in rural Cambodia.
  Asia Pacific journal of clinical nutrition 2015 McDonald CM, McLean J, Kroeun H, Talukder A, Lynd LD, Green TJ
• Effect of multivitamin supplementation on the neurodevelopment of HIV-exposed Tanzanian infants: a randomized, double-blind, placebo-controlled clinical trial.
  Journal of tropical pediatrics 2014 Manji KP, McDonald CM, Kupka R, Bosch RJ, Kisenge R, Aboud S, Bellinger DC, Fawzi WW, Duggan CP
• Associations of suboptimal growth with all-cause and cause-specific mortality in children under five years: a pooled analysis of ten prospective studies.
  PloS one 2013 Olofin I, McDonald CM, Ezzati M, Flaxman S, Black RE, Fawzi WW, Caulfield LE, Danaei G, Nutrition Impact Model Study (anthropometry cohort pooling)
• The effect of multiple anthropometric deficits on child mortality: meta-analysis of individual data in 10 prospective studies from developing countries.
  The American journal of clinical nutrition 2013 McDonald CM, Olofin I, Flaxman S, Fawzi WW, Spiegelman D, Caulfield LE, Black RE, Ezzati M, Danaei G, Nutrition Impact Model Study
• Stunting and wasting are associated with poorer psychomotor and mental development in HIV-exposed Tanzanian infants.
  The Journal of nutrition 2012 McDonald CM, Manji KP, Kupka R, Bellinger DC, Spiegelman D, Kisenge R, Msamanga G, Fawzi WW, Duggan CP
• Overweight is more prevalent than stunting and is associated with socioeconomic status, maternal obesity, and a snacking dietary pattern in school children from Bogota, Colombia.
  The Journal of nutrition 2008 McDonald CM, Baylin A, Arsenault JE, Mora-Plazas M, Villamor E
• Nutrition and exercise environment available to outpatients, visitors, and staff in Children's hospitals in Canada and the United States.
  Archives of pediatrics & adolescent medicine 2006 McDonald CM, Karamlou T, Wengle JG, Gibson J, McCrindle BW