Christina Yoon, MD, MPH
Associate Professor
Medicine
School of Medicine

Awards

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• Early Career Achievement Award, ATS, Pulmonary Infections and Tuberculosis Assembly, 2018
• Travel Award for Mid-Level Faculty, UCSF, Chancellor's Fund, 2018
• Outstanding Early Investigator in HIV/TB Research, NIH/UCSF-GIVI CFAR, 2015
• Loan Repayment Program Award, NIH, Loan Repayment Program, 2011-pres

Grants and Projects

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• Point-of-care C-reactive protein-based tuberculosis screening in people living with HIV: a randomized trial, NIH, 2019-2025
• Improving the efficiency of clinic-based active tuberculosis case finding: evaluation of point-of-care C-reactive protein-based triage testing in Vietnam., NIH, 2020-2022
• Point-of-care C-reactive protein-based tuberculosis screening in people living with HIV: a randomized trial, NIH, 2019-2021
• Evaluation of novel tuberculosis screening strategies for people living with HIV, NIH, 2014-2020
• Maximizing the impact of a mass TB screening campaign in the Marshall Islands by combining mass TB preventive therapy to active TB case finding to treatment, TB REACH/WHO-STOP TB Partnership, 2018-2020
• Point-of-care C-reactive protein-based tuberculosis screening among people living with HIV: planning a comparative effectiveness trial, NIH, 2017-2019

Publications (30)

Top publication keywords:
TuberculosisLatent TuberculosisMycobacterium tuberculosisPoint-of-Care SystemsPoint-of-Care TestingCD4 Lymphocyte CountAntitubercular AgentsTuberculosis, PulmonaryTransaminasesUgandaCoinfectionHIV InfectionsSputumC-Reactive ProteinIsoniazid

• Point-of-care C-reactive protein and Xpert MTB/RIF Ultra for tuberculosis screening and diagnosis in unselected antiretroviral therapy initiators: a prospective, cross-sectional, diagnostic accuracy study.
  The Lancet. Global health 2024 Reeve BWP, Ndlangalavu G, Mishra H, Palmer Z, Tshivhula H, Rockman L, Naidoo S, Mbu DL, Naidoo CC, Derendinger B, Walzl G, Malherbe ST, van Helden PD, Semitala FC, Yoon C, Gupta RK, Noursadeghi M, …
• Clinical utility of WHO-recommended screening tools and development and validation of novel clinical prediction models for pulmonary tuberculosis screening among outpatients living with HIV: an individual participant data meta-analysis.
  European respiratory review : an official journal of the European Respiratory Society 2023 Dhana A, Gupta RK, Hamada Y, Kengne AP, Kerkhoff AD, Yoon C, Cattamanchi A, Reeve BWP, Theron G, Ndlangalavu G, Wood R, Drain PK, Calderwood CJ, Noursadeghi M, Boyles T, Meintjes G, Maartens G, Barr …
• Point-of-care C-reactive protein and Xpert MTB/RIF Ultra for tuberculosis screening and diagnosis in unselected antiretroviral therapy initiators: a prospective diagnostic accuracy study.
  medRxiv : the preprint server for health sciences 2023 Reeve BW, Ndlangalavu G, Mishra H, Palmer Z, Tshivhula H, Rockman L, Naidoo S, Mbu DL, Naidoo CC, Derendinger B, Walzl G, Malherbe ST, van Helden PD, Semitala FC, Yoon C, Gupta RK, Noursadeghi M, …
• Diagnostic yield of urine lipoarabinomannan and sputum tuberculosis tests in people living with HIV: a systematic review and meta-analysis of individual participant data.
  The Lancet. Global health 2023 Broger T, Koeppel L, Huerga H, Miller P, Gupta-Wright A, Blanc FX, Esmail A, Reeve BWP, Floridia M, Kerkhoff AD, Ciccacci F, Kasaro MP, Thit SS, Bastard M, Ferlazzo G, Yoon C, Van Hoving DJ, Sossen B,…
• Viral suppression among adults with HIV receiving routine dolutegravir-based antiretroviral therapy and 3 months weekly isoniazid-rifapentine.
  AIDS (London, England) 2023 Chaisson LH, Semitala FC, Nangobi F, Steinmetz S, Marquez C, Armstrong DT, Opira B, Kamya MR, Phillips PPJ, Dowdy DW, Yoon C

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• The Role of C-Reactive Protein as a Triage Tool for Pulmonary Tuberculosis in Children.
  Journal of the Pediatric Infectious Diseases Society 2022 Jaganath D, Reza TF, Wambi P, Nakafeero J, Kiconco E, Nanyonga G, Oumo EA, Nsereko MC, Sekadde MP, Nabukenya-Mudiope MG, Kato-Maeda M, Andama A, Yoon C, Mohanty S, Wobudeya E, Cattamanchi A
• Transaminitis prevalence among HIV-infected adults eligible for tuberculosis preventive therapy.
  AIDS (London, England) 2022 Chaisson LH, Semitala FC, Mwebe S, Katende J, Asege L, Nakaye M, Andama AO, Atuhumuza E, Kamya M, Cattamanchi A, Yoon C
• Tuberculosis screening improves preventive therapy uptake (TB SCRIPT) trial among people living with HIV in Uganda: a study protocol of an individual randomized controlled trial.
  Trials 2022 Semitala FC, Chaisson LH, Dowdy DW, Armstrong DT, Opira B, Aman K, Kamya M, Phillips PPJ, Yoon C
• Tuberculosis screening among ambulatory people living with HIV: a systematic review and individual participant data meta-analysis.
  The Lancet. Infectious diseases 2021 Dhana A, Hamada Y, Kengne AP, Kerkhoff AD, Rangaka MX, Kredo T, Baddeley A, Miller C, Singh S, Hanifa Y, Grant AD, Fielding K, Affolabi D, Merle CS, Wachinou AP, Yoon C, Cattamanchi A, Hoffmann CJ, …
• C-Reactive Protein Testing for Active Tuberculosis among Inpatients without HIV in Uganda: a Diagnostic Accuracy Study.
  Journal of clinical microbiology 2020 Meyer AJ, Ochom E, Turimumahoro P, Byanyima P, Sanyu I, Lalitha R, Kaswabuli S, Andama A, Walter ND, Katamba A, Cattamanchi A, Worodria W, Huang L, Yoon C, Davis JL
• Impact of hematocrit on point-of-care C-reactive protein-based tuberculosis screening among people living with HIV initiating antiretroviral therapy in Uganda.
  Diagnostic microbiology and infectious disease 2020 Mwebe SZ, Yoon C, Asege L, Nakaye M, Katende J, Andama A, Cattamanchi A, Semitala FC
• Evaluation of multi-antigen serological screening for active tuberculosis among people living with HIV.
  PloS one 2020 Jaganath D, Rajan J, Yoon C, Ravindran R, Andama A, Asege L, Mwebe SZ, Katende J, Nakaye M, Semitala FC, Khan IH, Cattamanchi A
• Management and Outcomes of Critically-III Patients with COVID-19 Pneumonia at a Safety-net Hospital in San Francisco, a Region with Early Public Health Interventions: A Case Series.
  medRxiv : the preprint server for health sciences 2020 Vanderburg S, Alipanah N, Crowder R, Yoon C, Wang R, Thakur N, Slown K, Shete PB, Rofael M, Metcalfe JZ, Merrifield C, Marquez C, Malcolm K, Lipnick M, Jain V, Gomez A, Burns G, Brown LB, Berger C, …
• Brief Report: Yield and Efficiency of Intensified Tuberculosis Case-Finding Algorithms in 2 High-Risk HIV Subgroups in Uganda.
  Journal of acquired immune deficiency syndromes (1999) 2019 Semitala FC, Cattamanchi A, Andama A, Atuhumuza E, Katende J, Mwebe S, Asege L, Nakaye M, Kamya MR, Yoon C
• Guidance for Studies Evaluating the Accuracy of Tuberculosis Triage Tests.
  The Journal of infectious diseases 2019 Nathavitharana RR, Yoon C, Macpherson P, Dowdy DW, Cattamanchi A, Somoskovi A, Broger T, Ottenhoff THM, Arinaminpathy N, Lonnroth K, Reither K, Cobelens F, Gilpin C, Denkinger CM, Schumacher SG
• A Novel, 5-Transcript, Whole-blood Gene-expression Signature for Tuberculosis Screening Among People Living With Human Immunodeficiency Virus.
  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2019 Rajan JV, Semitala FC, Mehta T, Seielstad M, Montalvo L, Andama A, Asege L, Nakaye M, Katende J, Mwebe S, Kamya MR, Yoon C, Cattamanchi A
• Point-of-care C-reactive protein and risk of early mortality among adults initiating antiretroviral therapy.
  AIDS (London, England) 2019 Chaisson LH, Semitala FC, Asege L, Mwebe S, Katende J, Nakaye M, Andama AO, Marquez C, Atuhumuza E, Kamya M, Cattamanchi A, Yoon C
• Reply to Parker: Implications of Tuberculosis Sputum Culture Test Sensitivity on Accuracy of Other Diagnostic Modalities.
  American journal of respiratory and critical care medicine 2019 Yoon C, Semitala FC, Cattamanchi A
• Screening for tuberculosis: time to move beyond symptoms.
  The Lancet. Respiratory medicine 2019 Yoon C, Dowdy DW, Esmail H, MacPherson P, Schumacher SG
• Yield and Efficiency of Novel Intensified Tuberculosis Case-Finding Algorithms for People Living with HIV.
  American journal of respiratory and critical care medicine 2019 Yoon C, Semitala FC, Asege L, Katende J, Mwebe S, Andama AO, Atuhumuza E, Nakaye M, Armstrong DT, Dowdy DW, McCulloch CE, Kamya M, Cattamanchi A
• Diagnostic performance of blood inflammatory markers for tuberculosis screening in people living with HIV.
  PloS one 2018 Farr K, Ravindran R, Strnad L, Chang E, Chaisson LH, Yoon C, Worodria W, Andama A, Ayakaka I, Bbosa Nalwanga P, Byanyima P, Kalema N, Kaswabuli S, Katagira W, Aman KD, Musisi E, Tumwine NW, Sanyu I, …
• Diagnostic accuracy of C-reactive protein for active pulmonary tuberculosis: a meta-analysis.
  The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 2017 Yoon C, Chaisson LH, Patel SM, Allen IE, Drain PK, Wilson D, Cattamanchi A
• Point-of-care C-reactive protein-based tuberculosis screening for people living with HIV: a diagnostic accuracy study.
  The Lancet. Infectious diseases 2017 Yoon C, Semitala FC, Atuhumuza E, Katende J, Mwebe S, Asege L, Armstrong DT, Andama AO, Dowdy DW, Davis JL, Huang L, Kamya M, Cattamanchi A
• Blood Transcriptional Biomarkers for Active Tuberculosis among Patients in the United States: a Case-Control Study with Systematic Cross-Classifier Evaluation.
  Journal of clinical microbiology 2015 Walter ND, Miller MA, Vasquez J, Weiner M, Chapman A, Engle M, Higgins M, Quinones AM, Rosselli V, Canono E, Yoon C, Cattamanchi A, Davis JL, Phang T, Stearman RS, Datta G, Garcia BJ, Daley CL, Strong…
• Serum biomarkers of treatment response within a randomized clinical trial for pulmonary tuberculosis.
  Tuberculosis (Edinburgh, Scotland) 2015 Jayakumar A, Vittinghoff E, Segal MR, MacKenzie WR, Johnson JL, Gitta P, Saukkonen J, Anderson J, Weiner M, Engle M, Yoon C, Kato-Maeda M, Nahid P, Tuberculosis Trials Consortium
• Point-of-care C-reactive protein testing to facilitate implementation of isoniazid preventive therapy for people living with HIV.
  Journal of acquired immune deficiency syndromes (1999) 2014 Yoon C, Davis JL, Huang L, Muzoora C, Byakwaga H, Scibetta C, Bangsberg DR, Nahid P, Semitala FC, Hunt PW, Martin JN, Cattamanchi A
• Absence of peripheral blood chimerism in graft-vs-host disease following orthotopic liver transplantation: case report and review of the literature.
  International journal of dermatology 2013 Schulman JM, Yoon C, Schwarz J, Vagefi PA, Mully TW, Shinkai K
• C-reactive protein and tuberculosis screening: a new trick for an old dog?
  The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 2013 Yoon C, Davis JL, Cattamanchi A
• Dihydropteroate synthase mutations in Pneumocystis pneumonia: impact of applying different definitions of prophylaxis, mortality endpoints and mutant in a single cohort.
  Medical mycology 2013 Yoon C, Subramanian A, Chi A, Crothers K, Meshnick SR, Taylor SM, Beard CB, Jarlsberg LG, Lawrence GG, Avery M, Swartzman A, Fong S, Roth B, Huang L, International HIV-Associated Opportunistic …
• Impact of Xpert MTB/RIF testing on tuberculosis management and outcomes in hospitalized patients in Uganda.
  PloS one 2012 Yoon C, Cattamanchi A, Davis JL, Worodria W, den Boon S, Kalema N, Katagira W, Kaswabuli S, Miller C, Andama A, Albert H, Nabeta P, Gray C, Ayakaka I, Huang L