Christina Homer, MD, PhD
Clinical Fellow
Medicine
School of Medicine

Grants and Projects

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• Capsular-Independent Inhibition of Phagocytosis by Cryptococcus neoformans, NIH, 2015-2018

Publications (15)

Top publication keywords:
Fungal ProteinsCryptococcus neoformansrev Gene Products, Human Immunodeficiency VirusAspartic Acid ProteasesSchizosaccharomycesHeterochromatinGene Expression Regulation, FungalIntercellular Signaling Peptides and ProteinsVirulence FactorsCryptococcosisRNA SplicingSchizosaccharomyces pombe ProteinsMembrane Transport ProteinsRNA Polymerase IIQuorum Sensing

• Inferring the composition of a mixed culture of natural microbial isolates by deep sequencing.
  bioRxiv : the preprint server for biology 2024 Voorhies M, Joehnk B, Uehling J, Walcott K, Dubin C, Mead HL, Homer CM, Galgiani JN, Barker BM, Brem RB, Sil A
• Optimizing in vitro spherulation cues in the fungal pathogen Coccidioides.
  bioRxiv : the preprint server for biology 2024 Homer C, Ochoa E, Voorhies M, Sil A
• Proteome-wide Humoral Immune Profiling in Central Nervous System Coccidioidomycosis Using Programmable Phage Display (S25.004).
  Neurology 2024 Christine L. Boutros, Ravi Dandekar, Mark Voorhies, Christina Homer, George R. Thompson, Satya Dandekar, Anita Sil, Michael R. Wilson
• Embolic Hypodermic Needle Causing Traumatic Cardiac Tamponade: A Case Report.
  Critical care explorations 2019 Yen AF, Homer CM, Mohapatra A, Langnas E, Gomez A, Hendrickson CM
• Polymerase pausing induced by sequence-specific RNA-binding protein drives heterochromatin assembly.
  Genes & development 2018 Parsa JY, Boudoukha S, Burke J, Homer C, Madhani HD

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• Genome-wide analysis of the regulation of Cu metabolism in Cryptococcus neoformans.
  Molecular microbiology 2018 Garcia-Santamarina S, Festa RA, Smith AD, Yu CH, Probst C, Ding C, Homer CM, Yin J, Noonan JP, Madhani H, Perfect JR, Thiele DJ
• Polymerase pausing induced by sequence-specific RNA binding protein drives heterochromatin assembly.
  bioRxiv 2017 Jahan-Yar Parsa, Selim Boudoukha, Jordan Burke, Christina Homer, Hiten Madhani
• The histone variant H2A.Z promotes splicing of weak introns.
  Genes & development 2017 Nissen KE, Homer CM, Ryan CJ, Shales M, Krogan NJ, Patrick KL, Guthrie C
• Integrated Activity and Genetic Profiling of Secreted Peptidases in Cryptococcus neoformans Reveals an Aspartyl Peptidase Required for Low pH Survival and Virulence.
  PLoS pathogens 2016 Clarke SC, Dumesic PA, Homer CM, O'Donoghue AJ, La Greca F, Pallova L, Majer P, Madhani HD, Craik CS
• Phospho-site mutants of the RNA Polymerase II C-terminal domain alter subtelomeric gene expression and chromatin modification state in fission yeast.
  Nucleic acids research 2016 Inada M, Nichols RJ, Parsa JY, Homer CM, Benn RA, Hoxie RS, Madhani HD, Shuman S, Schwer B, Pleiss JA
• Intracellular Action of a Secreted Peptide Required for Fungal Virulence.
  Cell host & microbe 2016 Homer CM, Summers DK, Goranov AI, Clarke SC, Wiesner DL, Diedrich JK, Moresco JJ, Toffaletti D, Upadhya R, Caradonna I, Petnic S, Pessino V, Cuomo CA, Lodge JK, Perfect J, Yates JR, Nielsen K, Craik …
• Product binding enforces the genomic specificity of a yeast polycomb repressive complex.
  Cell 2014 Dumesic PA, Homer CM, Moresco JJ, Pack LR, Shanle EK, Coyle SM, Strahl BD, Fujimori DG, Yates JR, Madhani HD
• RNA-directed remodeling of the HIV-1 protein Rev orchestrates assembly of the Rev-Rev response element complex.
  eLife 2014 Jayaraman B, Crosby DC, Homer C, Ribeiro I, Mavor D, Frankel AD
• Using a Transcriptional Network to Approach the Mechanism of Fungal Meningitis.
  Biophysical Journal 2014 Christina M. Homer, Alexi Goranov, Dan Santos, Ippolito Caradonna, Sarah Petnic, Hiten D. Madhani
• Structural Basis for Phosphate Stabilization of the Uniquely Coordinated 2Fe-2S Cluster of the Outer Mitochondrial Membrane Protein MitoNEET.*.
  Biophysical Journal 2009 Christina Homer, David Yee, Herbert L. Axelrod, Aina E. Cohen, Edward C. Abresch, Charlene Chang, Rachel Nechushtai, Patricia A. Jennings, Mark L. Paddock